Page last updated: 2024-09-03

gefitinib and n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide

gefitinib has been researched along with n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide in 2 studies

Compound Research Comparison

Studies
(gefitinib)
Trials
(gefitinib)
Recent Studies (post-2010)
(gefitinib)
Studies
(n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide)
Trials
(n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide)
Recent Studies (post-2010) (n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide)
5,2315662,9191,2203229

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide (IC50)
Prostaglandin E synthaseHomo sapiens (human)10
Prostaglandin G/H synthase 1Ovis aries (sheep)2.1
AromataseHomo sapiens (human)0.68
Prostaglandin G/H synthase 1Mus musculus (house mouse)1.67
Prostaglandin G/H synthase 1Homo sapiens (human)3
Prostaglandin G/H synthase 2Homo sapiens (human)0.9037
Prostaglandin G/H synthase 2Ovis aries (sheep)2.4333
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.1522
Carboxypeptidase B2Homo sapiens (human)1.8
Prostaglandin E synthaseMus musculus (house mouse)0.007

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Attoub, S; Bruyneel, E; Emami, S; Gespach, C; Mareel, M; May, FE; Nguyen, QD; Rodrigues, S; Thim, L; Van Aken, E; Van Bocxlaer, S; Westley, BR1
Lin, J; Pan, W; Shi, H; Wu, H; Yu, H; Zhu, J1

Other Studies

2 other study(ies) available for gefitinib and n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide

ArticleYear
Trefoil peptides as proangiogenic factors in vivo and in vitro: implication of cyclooxygenase-2 and EGF receptor signaling.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:1

    Topics: Allantois; Angiogenesis Inducing Agents; Animals; Capillaries; Cells, Cultured; Chick Embryo; Chorion; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; ErbB Receptors; Gefitinib; Growth Substances; Humans; Isoenzymes; Membrane Proteins; Morphogenesis; Mucins; Muscle Proteins; Neovascularization, Physiologic; Neuropeptides; Nitrobenzenes; Peptides; Prostaglandin-Endoperoxide Synthases; Quinazolines; Signal Transduction; Sulfonamides; Trefoil Factor-2; Trefoil Factor-3

2003
Combined inhibition of epidermal growth factor receptor and cyclooxygenase-2 leads to greater anti-tumor activity of docetaxel in advanced prostate cancer.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cell Proliferation; Cyclooxygenase 2; Docetaxel; ErbB Receptors; Flow Cytometry; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Staging; NF-kappa B; Nitrobenzenes; Prostatic Neoplasms; Quinazolines; Sulfonamides; Taxoids; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2013