Page last updated: 2024-09-03

gefitinib and ml-3000

gefitinib has been researched along with ml-3000 in 3 studies

Compound Research Comparison

Studies
(gefitinib)
Trials
(gefitinib)
Recent Studies (post-2010)
(gefitinib)
Studies
(ml-3000)
Trials
(ml-3000)
Recent Studies (post-2010) (ml-3000)
5,2315662,919130956

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)ml-3000 (IC50)
Prostaglandin E synthaseHomo sapiens (human)6.14
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.1925
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.21
Prostaglandin G/H synthase 1Ovis aries (sheep)0.185
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)0.3017
Polyunsaturated fatty acid 5-lipoxygenaseRattus norvegicus (Norway rat)3.6
Prostaglandin G/H synthase 1Homo sapiens (human)2.7425
Prostaglandin G/H synthase 2Homo sapiens (human)0.422
5-lipoxygenase Bos taurus (cattle)0.47

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Brewer, M; Janakiram, NB; Mohammed, A; Rao, CV; Steele, VE; Vedala, K1
Biddick, L; Brewer, M; Devarkonda, V; Janakiram, NB; Lightfoot, S; Madka, V; Mohammed, A; Rao, CV; Steele, VE1

Other Studies

3 other study(ies) available for gefitinib and ml-3000

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Multitargeted low-dose GLAD combination chemoprevention: a novel and promising approach to combat colon carcinogenesis.
    Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:5

    Topics: Adenomatous Polyps; Animals; Antineoplastic Combined Chemotherapy Protocols; Atorvastatin; Carcinogenesis; Cell Proliferation; Chemoprevention; Colon; Colonic Neoplasms; Cytokines; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Eflornithine; Female; Gefitinib; Heptanoic Acids; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Targeted Therapy; Pyrroles; Quinazolines

2013
Simultaneous targeting of 5-LOX-COX and EGFR blocks progression of pancreatic ductal adenocarcinoma.
    Oncotarget, 2015, Oct-20, Volume: 6, Issue:32

    Topics: Animals; Antineoplastic Agents; Arachidonate 5-Lipoxygenase; Carcinoma, Pancreatic Ductal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Synergism; ErbB Receptors; Female; Gefitinib; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pancreatic Neoplasms; Pyrroles; Quinazolines; Signal Transduction

2015