Compounds > gefitinib
Page last updated: 2024-09-03

gefitinib and methapyrilene

gefitinib has been researched along with methapyrilene in 2 studies

Compound Research Comparison

Studies
(gefitinib)		Trials
(gefitinib)		Recent Studies (post-2010)
(gefitinib)		Studies
(methapyrilene)		Trials
(methapyrilene)		Recent Studies (post-2010) (methapyrilene)
5,2315662,919206325

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)methapyrilene (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.744
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.391
Muscarinic acetylcholine receptor M2Homo sapiens (human)1.665
Muscarinic acetylcholine receptor M5Homo sapiens (human)3.265
Alpha-2A adrenergic receptorHomo sapiens (human)1.165
Cytochrome P450 2D6Homo sapiens (human)2.7564
Muscarinic acetylcholine receptor M1Homo sapiens (human)4.773
Alpha-2B adrenergic receptorHomo sapiens (human)3.318
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.391
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.628
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.744
Sodium-dependent serotonin transporterHomo sapiens (human)0.2
Histamine H1 receptorHomo sapiens (human)0.016
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.843
5-hydroxytryptamine receptor 6Homo sapiens (human)3.091
Sodium-dependent dopamine transporter Homo sapiens (human)2.757

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Ekins, S; Williams, AJ; Xu, JJ1

Other Studies

2 other study(ies) available for gefitinib and methapyrilene

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010