Compounds > gefitinib
Page last updated: 2024-09-03

gefitinib and masoprocol

gefitinib has been researched along with masoprocol in 3 studies

Compound Research Comparison

Studies
(gefitinib)		Trials
(gefitinib)		Recent Studies (post-2010)
(gefitinib)		Studies
(masoprocol)		Trials
(masoprocol)		Recent Studies (post-2010) (masoprocol)
5,2315662,919138063
5,2315662,9191,5278163

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)masoprocol (IC50)
RNA polymerase beta subunit (EC 2.7.7.6), partialEscherichia coli12.4362
90-kda heat shock protein beta HSP90 beta, partialHomo sapiens (human)2.6232
Estrogen receptor 1Homo sapiens (human)22.1937
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonasePlasmodium berghei61.65
heat shock protein HSP 90-alpha isoform 2Homo sapiens (human)2.6232
Proto-oncogene c-FosHomo sapiens (human)0.0079
Transcription factor AP-1Homo sapiens (human)0.0079
Insulin-like growth factor 1 receptorHomo sapiens (human)0.9
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)3.5
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)0.2915
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 22.59
AromataseHomo sapiens (human)0.011
Polyunsaturated fatty acid 5-lipoxygenaseRattus norvegicus (Norway rat)0.752
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)0.11
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)5.5
Polyunsaturated fatty acid lipoxygenase ALOX15Homo sapiens (human)1.5114
Polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)2.778
17-beta-hydroxysteroid dehydrogenase type 2Homo sapiens (human)0.38
Alpha-synucleinHomo sapiens (human)0.215
Polyunsaturated fatty acid 5-lipoxygenaseMus musculus (house mouse)0.4
Leukotriene B4 receptor 1Homo sapiens (human)0.085
Lipoxygenase Glycine max (soybean)4.865
5-lipoxygenase Bos taurus (cattle)0.7
large T antigenBetapolyomavirus macacae21.86
Prostaglandin G/H synthase 1Ovis aries (sheep)3.5
Prostaglandin G/H synthase 2Homo sapiens (human)3.5

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP1
Allan, G; Campbell, MJ; Goldfine, ID; Hodges, L; Kerner, JA; Kushner, P; Maddux, BA; Shiry, L; Youngren, JF; Zavodovskaya, M1

Other Studies

3 other study(ies) available for gefitinib and masoprocol

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water

2010
Nordihydroguaiaretic acid (NDGA), an inhibitor of the HER2 and IGF-1 receptor tyrosine kinases, blocks the growth of HER2-overexpressing human breast cancer cells.
    Journal of cellular biochemistry, 2008, Feb-01, Volume: 103, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Apoptosis; Breast Neoplasms; Cell Division; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drug Synergism; Female; Gefitinib; Humans; Insulin-Like Growth Factor Binding Protein 3; Masoprocol; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Quinazolines; Receptor, ErbB-2; Receptor, IGF Type 1; Selective Estrogen Receptor Modulators; Tamoxifen

2008