Compounds > gefitinib
Page last updated: 2024-09-03

gefitinib and lonafarnib

gefitinib has been researched along with lonafarnib in 2 studies

Compound Research Comparison

Studies
(gefitinib)		Trials
(gefitinib)		Recent Studies (post-2010)
(gefitinib)		Studies
(lonafarnib)		Trials
(lonafarnib)		Recent Studies (post-2010) (lonafarnib)
5,2315662,9192243490

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)lonafarnib (IC50)
Chain A, Protein farnesyltransferase alpha subunitRattus norvegicus (Norway rat)0.0019
Chain B, Protein farnesyltransferase beta subunitRattus norvegicus (Norway rat)0.0019
GTPase HRasHomo sapiens (human)0.07
ATP-dependent translocase ABCB1Homo sapiens (human)2.7
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaBos taurus (cattle)0.0081
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaHomo sapiens (human)0.1498
Protein farnesyltransferase subunit betaBos taurus (cattle)0.0081
Protein farnesyltransferase subunit betaHomo sapiens (human)0.1498
Protein farnesyltransferase subunit betaRattus norvegicus (Norway rat)0.0019
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaRattus norvegicus (Norway rat)0.0019

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kurisu, K; Okamura, T1
Bernhard, JC; Ferrière, JM; Ravaud, A; Robert, G; Wallerand, H1

Reviews

2 review(s) available for gefitinib and lonafarnib

ArticleYear
[Molecular targeted therapy for malignant brain tumors].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 9

    Topics: Antineoplastic Agents; Benzamides; Brain Neoplasms; Drug Delivery Systems; Drug Design; Drug Resistance, Neoplasm; Drug Therapy, Combination; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Glioma; Humans; Imatinib Mesylate; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperazines; Piperidines; Protein Kinases; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Quinazolines; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2005
[Targeted therapy for locally advanced and/or metastatic bladder cancer].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2008, Volume: 18, Issue:7

    Topics: Angiogenesis Inhibitors; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Disease Progression; Erlotinib Hydrochloride; Gefitinib; Genetic Therapy; Humans; Immunosuppressive Agents; Mutation; Piperidines; Protein Kinase Inhibitors; Pyridines; Quinazolines; Randomized Controlled Trials as Topic; Signal Transduction; Sirolimus; Targeted Gene Repair; Trastuzumab; Urinary Bladder Neoplasms

2008