Compounds > gefitinib
Page last updated: 2024-09-03

gefitinib and indirubin-3'-monoxime

gefitinib has been researched along with indirubin-3'-monoxime in 2 studies

Compound Research Comparison

Studies
(gefitinib)		Trials
(gefitinib)		Recent Studies (post-2010)
(gefitinib)		Studies
(indirubin-3'-monoxime)		Trials
(indirubin-3'-monoxime)		Recent Studies (post-2010) (indirubin-3'-monoxime)
5,2315662,919139082

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)indirubin-3'-monoxime (IC50)
Chain A, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)0.022
Chain B, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)0.022
Chain A, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)0.022
Glycogen synthase kinase-3 beta Sus scrofa (pig)0.022
[Tau protein] kinase Sus scrofa (pig)0.022
Serine/threonine-protein kinase Sgk1Homo sapiens (human)0.38
Aurora kinase AHomo sapiens (human)4
Cyclin-T1Homo sapiens (human)2.4
Serine/threonine-protein kinase 17BHomo sapiens (human)0.71
G2/mitotic-specific cyclin-B2Homo sapiens (human)0.099
Tyrosine-protein kinase LckHomo sapiens (human)0.3
Cyclin-dependent kinase 1Homo sapiens (human)0.126
Insulin-like growth factor 1 receptorHomo sapiens (human)5.3
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)8.2
Fibroblast growth factor receptor 1Homo sapiens (human)2.5
Cyclin-dependent kinase 4Homo sapiens (human)3.33
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.099
Interferon-induced, double-stranded RNA-activated protein kinaseHomo sapiens (human)0.1
Cyclin-A2Homo sapiens (human)0.515
G1/S-specific cyclin-D1Homo sapiens (human)3.33
G1/S-specific cyclin-E1Homo sapiens (human)0.7
Cyclin-dependent kinase 2Homo sapiens (human)0.5767
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.0785
Glycogen synthase kinase-3 alphaHomo sapiens (human)0.022
Glycogen synthase kinase-3 betaHomo sapiens (human)0.0599
Cyclin-dependent kinase 9Homo sapiens (human)2.4
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.1
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)0.1
G2/mitotic-specific cyclin-B3Homo sapiens (human)0.099
Aurora kinase BHomo sapiens (human)2.3
Aurora kinase CHomo sapiens (human)0.3

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1

Other Studies

2 other study(ies) available for gefitinib and indirubin-3'-monoxime

ArticleYear
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013