gefitinib has been researched along with ebastine in 2 studies
| Studies (gefitinib) | Trials (gefitinib) | Recent Studies (post-2010) (gefitinib) | Studies (ebastine) | Trials (ebastine) | Recent Studies (post-2010) (ebastine) |
|---|---|---|---|---|---|
| 5,231 | 566 | 2,919 | 237 | 75 | 58 |
| Protein | Taxonomy | gefitinib (IC50) | ebastine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.2375 | |
| Epidermal growth factor receptor | Homo sapiens (human) | 0.5591 | |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | 1.0575 | |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 0.8101 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.4603 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.786 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.8279 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 1.5 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.047 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.3378 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.8316 | |
| Adenosine receptor A3 | Homo sapiens (human) | 3.1953 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 0.92 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.8734 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 0.1048 | |
| Beta-3 adrenergic receptor | Homo sapiens (human) | 2.5455 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.605 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 1.1871 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.7389 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.2757 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.6475 | |
| Substance-K receptor | Homo sapiens (human) | 1.9329 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 1.1929 | |
| D(4) dopamine receptor | Homo sapiens (human) | 1.2996 | |
| Acetylcholinesterase | Homo sapiens (human) | 7.4799 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.183 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.4603 | |
| Histamine H2 receptor | Homo sapiens (human) | 2.9157 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.9771 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.0904 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.2375 | |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | 0.047 | |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | 0.045 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 1.2287 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 0.183 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.0283 | |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | 0.183 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.1216 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.3126 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 1.1871 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 2.1974 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.0987 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 1.152 | |
| 5-hydroxytryptamine receptor 4 | Homo sapiens (human) | 0.061 | |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | 0.1048 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Capuzzi, SJ; Fisher, EG; García-Sastre, A; He, S; Li, H; Martínez-Romero, C; Muratov, EN; Qiu, X; Shinn, P; Sun, W; Tawa, G; Tropsha, A; Xu, M; Zheng, W; Zhu, W | 1 |
2 other study(ies) available for gefitinib and ebastine
| Article | Year |
|---|---|
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Computer-Aided Discovery and Characterization of Novel Ebola Virus Inhibitors.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Drug Discovery; Drug Evaluation, Preclinical; Ebolavirus; HeLa Cells; Humans; Molecular Structure; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Virus Internalization | 2018 |