Page last updated: 2024-09-03

gefitinib and d-alpha tocopherol

gefitinib has been researched along with d-alpha tocopherol in 7 studies

Compound Research Comparison

Studies
(gefitinib)
Trials
(gefitinib)
Recent Studies (post-2010)
(gefitinib)
Studies
(d-alpha tocopherol)
Trials
(d-alpha tocopherol)
Recent Studies (post-2010) (d-alpha tocopherol)
5,2315662,91932,1982,9037,258

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)d-alpha tocopherol (IC50)
Glutathione S-transferase PHomo sapiens (human)0.5

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (85.71)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dvorák, J; Hyspler, R; Kalábová, H; Kasparová, M; Krcmová, L; Melichar, B; Solichová, D; Urbánek, L1
Bachawal, SV; Sylvester, PW; Wali, VB2
Chen, JN; Chen, SY; Lin, PS; Liu, HC; Wei, CW; Yiang, GT1
Alanazi, FK; Alqahtani, AS; Harisa, GI; Nasr, FA; Sherif, AY1

Reviews

1 review(s) available for gefitinib and d-alpha tocopherol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

6 other study(ies) available for gefitinib and d-alpha tocopherol

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Intestinal permeability, vitamin A absorption and serum alpha-tocopherol during therapy with gefitinib.
    Scandinavian journal of clinical and laboratory investigation, 2010, Apr-19, Volume: 70, Issue:3

    Topics: Adult; Aged; alpha-Tocopherol; Case-Control Studies; Female; Gefitinib; Humans; Intestinal Absorption; Intestines; Male; Middle Aged; Permeability; Quinazolines; Vitamin A

2010
Enhanced antiproliferative and apoptotic response to combined treatment of gamma-tocotrienol with erlotinib or gefitinib in mammary tumor cells.
    BMC cancer, 2010, Mar-08, Volume: 10

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromans; Culture Media, Serum-Free; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Mammary Neoplasms, Animal; Mice; Quinazolines; Signal Transduction; Trastuzumab; Vitamin E

2010
Combined gamma-tocotrienol and erlotinib/gefitinib treatment suppresses Stat and Akt signaling in murine mammary tumor cells.
    Anticancer research, 2010, Volume: 30, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cell Proliferation; Chromans; Erlotinib Hydrochloride; Female; Gefitinib; Mammary Neoplasms, Animal; Mice; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; STAT Transcription Factors; Vitamin E

2010
Combined treatment with vitamin E and gefitinib has synergistic effects to inhibit TGF-β1-induced renal fibroblast proliferation.
    Molecular medicine reports, 2016, Volume: 13, Issue:6

    Topics: Animals; Cell Line; Cell Proliferation; Drug Synergism; Fibroblasts; Gefitinib; Gene Expression Regulation; Kidney; MAP Kinase Signaling System; Quinazolines; Rats; Transforming Growth Factor beta1; Vitamin E

2016
Engineered Nanoscale Lipid-Based Formulation as Potential Enhancer of Gefitinib Lymphatic Delivery: Cytotoxicity and Apoptotic Studies Against the A549 Cell Line.
    AAPS PharmSciTech, 2022, Jul-01, Volume: 23, Issue:6

    Topics: A549 Cells; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Gefitinib; Humans; Lipids; Lung Neoplasms; Nanoparticles; Particle Size; Vitamin E

2022