Compounds > gefitinib
Page last updated: 2024-09-03

gefitinib and cucurbitacin b

gefitinib has been researched along with cucurbitacin b in 3 studies

Compound Research Comparison

Studies
(gefitinib)		Trials
(gefitinib)		Recent Studies (post-2010)
(gefitinib)		Studies
(cucurbitacin b)		Trials
(cucurbitacin b)		Recent Studies (post-2010) (cucurbitacin b)
5,2315662,9191760130

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Alp, E; Elmazoglu, Z; Menevse, S; Yar Saglam, AS1
Chen, S; Liu, P; Liu, X; Liu, Y; Si, Y; Xiang, Y; Xu, L; Yang, R; Yu, Q; Zhang, L; Zhang, T; Zhao, H1
Lin, Y; Tang, H; Wang, W; Yu, B; Zheng, L1

Other Studies

3 other study(ies) available for gefitinib and cucurbitacin b

ArticleYear
Treatment with cucurbitacin B alone and in combination with gefitinib induces cell cycle inhibition and apoptosis via EGFR and JAK/STAT pathway in human colorectal cancer cell lines.
    Human & experimental toxicology, 2016, Volume: 35, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Cell Survival; ErbB Receptors; Gefitinib; HCT116 Cells; HT29 Cells; Humans; Janus Kinases; Microscopy, Fluorescence; Quinazolines; Real-Time Polymerase Chain Reaction; Signal Transduction; STAT Transcription Factors; Triterpenes

2016
Cucurbitacin B Induces the Lysosomal Degradation of EGFR and Suppresses the CIP2A/PP2A/Akt Signaling Axis in Gefitinib-Resistant Non-Small Cell Lung Cancer.
    Molecules (Basel, Switzerland), 2019, Feb-12, Volume: 24, Issue:3

    Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Autoantigens; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Lysosomes; Male; Membrane Proteins; Mice; Mice, Nude; Protein Kinase Inhibitors; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Signal Transduction; Triterpenes

2019
Cucurbitacin B enhances apoptosis in gefitinib resistant non‑small cell lung cancer by modulating the miR‑17‑5p/STAT3 axis.
    Molecular medicine reports, 2021, Volume: 24, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Resistance, Neoplasm; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; STAT3 Transcription Factor; Triterpenes

2021