Page last updated: 2024-09-03

gefitinib and cryptotanshinone

gefitinib has been researched along with cryptotanshinone in 2 studies

Compound Research Comparison

Studies
(gefitinib)
Trials
(gefitinib)
Recent Studies (post-2010)
(gefitinib)
Studies
(cryptotanshinone)
Trials
(cryptotanshinone)
Recent Studies (post-2010) (cryptotanshinone)
5,2315662,9193700268

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)cryptotanshinone (IC50)
Chain A, RNA-directed RNA polymerase NS5Dengue virus 2 16681-PDK5390.06
Lysine-specific histone demethylase 1AHomo sapiens (human)9.02
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirus0.8
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 23.722
Indoleamine 2,3-dioxygenase 1Homo sapiens (human)10
Signal transducer and activator of transcription 3Homo sapiens (human)4.6
Tryptophan 2,3-dioxygenaseHomo sapiens (human)9.8
Hypoxia-inducible factor 1-alphaHomo sapiens (human)1.47
Endothelial PAS domain-containing protein 1Homo sapiens (human)1.47

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Fu, J; Han, S; Jia, Q; Lin, Y; Lv, Y1
Bai, X; Cai, P; Cao, L; Hong, W; Huang, M; Jin, J; Xu, C; Zhao, Z1

Other Studies

2 other study(ies) available for gefitinib and cryptotanshinone

ArticleYear
Dual-mixed/CMC model for screening target components from traditional Chinese medicines simultaneously acting on EGFR & FGFR4 receptors.
    Talanta, 2019, Jan-15, Volume: 192

    Topics: Abietanes; Alkenes; Cell Proliferation; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; ErbB Receptors; Gefitinib; HEK293 Cells; Humans; Phenanthrenes; Polyphenols; Protein Kinase Inhibitors; Receptor, Fibroblast Growth Factor, Type 4; Salvia miltiorrhiza; Sorafenib; Spectrometry, Mass, Electrospray Ionization

2019
Cryptotanshinone strengthens the effect of gefitinib against non-small cell lung cancer through inhibiting transketolase.
    European journal of pharmacology, 2021, Jan-05, Volume: 890

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Female; Fibroblasts; Gefitinib; Gene Knockdown Techniques; Humans; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; NF-E2-Related Factor 2; Phenanthrenes; Transketolase; Up-Regulation; Xenograft Model Antitumor Assays

2021