Page last updated: 2024-09-03

gefitinib and bms 754807

gefitinib has been researched along with bms 754807 in 2 studies

Compound Research Comparison

Studies
(gefitinib)
Trials
(gefitinib)
Recent Studies (post-2010)
(gefitinib)
Studies
(bms 754807)
Trials
(bms 754807)
Recent Studies (post-2010) (bms 754807)
5,2315662,91955046

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)bms 754807 (IC50)
G1/S-specific cyclin-E2Homo sapiens (human)1.035
High affinity nerve growth factor receptorHomo sapiens (human)0.007
Insulin receptorHomo sapiens (human)0.0017
Insulin-like growth factor 1 receptorHomo sapiens (human)0.0036
Cytochrome P450 3A4Homo sapiens (human)7
Cytochrome P450 2D6Homo sapiens (human)0.0021
G1/S-specific cyclin-E1Homo sapiens (human)1.035
Cyclin-dependent kinase 2Homo sapiens (human)1.035
RAC-alpha serine/threonine-protein kinase Mus musculus (house mouse)0.022
BDNF/NT-3 growth factors receptorHomo sapiens (human)0.004
Insulin-like growth factor 1 receptorMus musculus (house mouse)0.013
Serine/threonine-protein kinase LMTK3Homo sapiens (human)3.161

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aiche, S; Bassermann, F; Becker, W; Canevari, G; Casale, E; Depaolini, SR; Ehrlich, HC; Felder, ER; Feuchtinger, A; Garz, AK; Gohlke, BO; Götze, K; Greif, PA; Hahne, H; Heinzlmeir, S; Helm, D; Huenges, J; Jeremias, I; Kayser, G; Klaeger, S; Koch, H; Koenig, PA; Kramer, K; Kuster, B; Médard, G; Meng, C; Petzoldt, S; Polzer, H; Preissner, R; Qiao, H; Reinecke, M; Reiter, K; Rueckert, L; Ruland, J; Ruprecht, B; Schlegl, J; Schmidt, T; Schneider, S; Schoof, M; Spiekermann, K; Tõnisson, N; Vick, B; Vooder, T; Walch, A; Wilhelm, M; Wu, Z; Zecha, J; Zolg, DP1
Ahn, JH; Kim, EJ; Kim, SW; Kim, SY; Lee, HJ; Lee, SJ; Moon, DH; Oh, SJ; Ryu, JS1

Other Studies

2 other study(ies) available for gefitinib and bms 754807

ArticleYear
The target landscape of clinical kinase drugs.
    Science (New York, N.Y.), 2017, 12-01, Volume: 358, Issue:6367

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytokines; Drug Discovery; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Mice; Molecular Targeted Therapy; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proteomics; Xenograft Model Antitumor Assays

2017
A pilot study for the early assessment of the effects of BMS-754807 plus gefitinib in an H292 tumor model by [(18)F]fluorothymidine-positron emission tomography.
    Investigational new drugs, 2013, Volume: 31, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Fluorine Radioisotopes; Gefitinib; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Pilot Projects; Positron-Emission Tomography; Protein Kinase Inhibitors; Pyrazoles; Quinazolines; Receptor, IGF Type 1; Thymidine; Triazines; Tumor Burden

2013