Page last updated: 2024-09-03

gefitinib and benzo(a)pyrene

gefitinib has been researched along with benzo(a)pyrene in 2 studies

Compound Research Comparison

Studies (gefitinib)	Trials (gefitinib)	Recent Studies (post-2010) (gefitinib)	Studies (benzo(a)pyrene)	Trials (benzo(a)pyrene)	Recent Studies (post-2010) (benzo(a)pyrene)
5,231	566	2,919	7,311	17	2,154

Protein Interaction Comparison

Protein	Taxonomy	gefitinib (IC50)	benzo(a)pyrene (IC50)
Cytochrome P450 1A2	Homo sapiens (human)		0.04
Amine oxidase [flavin-containing] A	Homo sapiens (human)		5.972

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hong, JH; Ko, JC; Lin, YW; Wang, LH	1
Kometani, T; Maehara, Y; Miura, N; Ohba, T; Okazaki, H; Shoji, F; Takenaka, T; Yano, T; Yoshino, I	1

Other Studies

2 other study(ies) available for gefitinib and benzo(a)pyrene

Article	Year
The role of repair protein Rad51 in synergistic cytotoxicity and mutagenicity induced by epidermal growth factor receptor inhibitor (Gefitinib, IressaR) and benzo[a]pyrene in human lung cancer. Experimental cell research, 2008, May-01, Volume: 314, Issue:8 Topics: Antineoplastic Agents; Benzo(a)pyrene; Cell Line, Tumor; Cell Proliferation; Drug Synergism; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Humans; Lung Neoplasms; MAP Kinase Kinase 1; Mutagens; Proteasome Endopeptidase Complex; Quinazolines; Rad51 Recombinase; RNA Interference	2008
Benzo[a]pyrene promotes proliferation of human lung cancer cells by accelerating the epidermal growth factor receptor signaling pathway. Cancer letters, 2009, Jun-08, Volume: 278, Issue:1 Topics: Adenocarcinoma; Antineoplastic Agents; Benzo(a)pyrene; Cell Culture Techniques; Cell Division; Cell Proliferation; ErbB Receptors; Gefitinib; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Signal Transduction	2009

Article

Year

The role of repair protein Rad51 in synergistic cytotoxicity and mutagenicity induced by epidermal growth factor receptor inhibitor (Gefitinib, IressaR) and benzo[a]pyrene in human lung cancer.

Experimental cell research, 2008, May-01, Volume: 314, Issue:8

Topics: Antineoplastic Agents; Benzo(a)pyrene; Cell Line, Tumor; Cell Proliferation; Drug Synergism; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Humans; Lung Neoplasms; MAP Kinase Kinase 1; Mutagens; Proteasome Endopeptidase Complex; Quinazolines; Rad51 Recombinase; RNA Interference

2008

Benzo[a]pyrene promotes proliferation of human lung cancer cells by accelerating the epidermal growth factor receptor signaling pathway.

Cancer letters, 2009, Jun-08, Volume: 278, Issue:1

Topics: Adenocarcinoma; Antineoplastic Agents; Benzo(a)pyrene; Cell Culture Techniques; Cell Division; Cell Proliferation; ErbB Receptors; Gefitinib; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Signal Transduction

2009