Compounds > gefitinib
Page last updated: 2024-09-03

gefitinib and bafilomycin a1

gefitinib has been researched along with bafilomycin a1 in 3 studies

Compound Research Comparison

Studies
(gefitinib)		Trials
(gefitinib)		Recent Studies (post-2010)
(gefitinib)		Studies
(bafilomycin a1)		Trials
(bafilomycin a1)		Recent Studies (post-2010) (bafilomycin a1)
5,2315662,9191,1201484

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)bafilomycin a1 (IC50)
P2X purinoceptor 3Homo sapiens (human)0.755
V-type proton ATPase subunit S1Homo sapiens (human)0.1
Vacuolar proton pump subunit B Gallus gallus (chicken)0.03

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chang, YH; Hong, SE; Hong, SI; Hong, YJ; Jin, HO; Kim, B; Kim, CS; Kim, JH; Kim, JY; Lee, JK; Park, IC; Park, JA1
He, KW; Huo, ZJ; Liu, ZY; Ma, QH; Song, XG; Wang, XW; Wang, XZ; Yu, ZY; Zhuo, PY1
He, K; Liu, C; Liu, Z; Ma, Q; Ndege, I; Wang, X; Yu, Q; Yu, Z1

Other Studies

3 other study(ies) available for gefitinib and bafilomycin a1

ArticleYear
Combined effects of EGFR tyrosine kinase inhibitors and vATPase inhibitors in NSCLC cells.
    Toxicology and applied pharmacology, 2015, Aug-15, Volume: 287, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lapatinib; Lung Neoplasms; Macrolides; Membrane Proteins; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Quinazolines; RNA Interference; Transfection; Vacuolar Proton-Translocating ATPases

2015
[Effect of autophagy inhibitor combined with EGFR inhibitor on triple-negative breast cancer MDA-MB-468 and MDA-MB-231 cells].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2016, Jun-23, Volume: 38, Issue:6

    Topics: Adenine; Antineoplastic Agents; Autophagy; Autophagy-Related Proteins; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Gefitinib; Humans; Macrolides; MCF-7 Cells; Microtubule-Associated Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Quinazolines; Triple Negative Breast Neoplasms

2016
Autophagy inhibitor facilitates gefitinib sensitivity in vitro and in vivo by activating mitochondrial apoptosis in triple negative breast cancer.
    PloS one, 2017, Volume: 12, Issue:5

    Topics: Adenine; Animals; Autophagy; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Cytochromes c; Drug Synergism; Female; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Macrolides; Mice; Mice, Nude; Mitochondria; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays

2017