gefarnate has been researched along with cetraxate* in 3 studies
3 other study(ies) available for gefarnate and cetraxate
| Article | Year |
|---|---|
[Drug administration schedule of anti-ulcer agents to prevent recurrence of peptic ulcer; administration of synergistic drugs for protective factors in peptic ulcer--criteria of drug selection according to clinical symptoms and administration methods].
Topics: Anti-Ulcer Agents; Cyclohexanecarboxylic Acids; Diterpenes; Gefarnate; Humans; Peptic Ulcer; Recurrence; Sucralfate; Tranexamic Acid | 1988 |
[Drug administration schedule of anti-ulcer agents to prevent recurrence of peptic ulcer; combination therapy of inhibitors of attacking factors and synergistic drugs for protective factors in peptic ulcer--selection of drug combinations and clinical effi
Topics: Anti-Ulcer Agents; Cimetidine; Drug Administration Schedule; Drug Therapy, Combination; Gefarnate; Humans; Peptic Ulcer; Ranitidine; Recurrence; Sulpiride; Tranexamic Acid | 1988 |
A new screening method for anti-ulcer agents: psychological stress produced by intraspecies emotional communication.
Psychological stress produced by intraspecies emotional communication in a communication box was studied to see whether it could be applied to a new screening method for anti-ulcer agents. There were two groups of mice, the 'sender' mice that received electrical foot shocks and showed emotional responses such as piloerection, abnormal squealing and jumping, and the 'responder' mice that were affected by the sender's emotional responses without foot shock. The gastric lesions (erosions) produced by conditioned emotional stimuli were observed in both groups. The effects of the anti-ulcer drugs cetraxate, cimetidine and gefarnate were examined. In 'senders', the gastric lesions were significantly suppressed by the administration of cetraxate at a dose of 200 mg/kg (p.o.) or cimetidine at doses of 30 and 100 mg/kg (p.o.). The gastric lesions in 'responders' were significantly suppressed by two administrations of cetraxate at doses of 100 and 200 mg/kg (p.o.), cimetidine at doses of 10-100 mg/kg (p.o.) or gefarnate at a dose of 200 mg/kg (p.o.). The gastric lesions of 'responders' were more sensitive to anti-ulcer drugs. The present results indicate that the gastric erosions of 'responders' are useful for the evaluation of anti-ulcer agents. Topics: Animal Communication; Animals; Anti-Ulcer Agents; Cimetidine; Drug Evaluation, Preclinical; Electroshock; Gastric Mucosa; Gefarnate; Male; Mice; Peptic Ulcer; Stress, Psychological; Tranexamic Acid | 1987 |