Page last updated: 2024-09-04

ge 68 and verapamil

ge 68 has been researched along with verapamil in 2 studies

*Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent. [MeSH]

*Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent. [MeSH]

Compound Research Comparison

Studies
(ge 68)
Trials
(ge 68)
Recent Studies (post-2010)
(ge 68)
Studies
(verapamil)
Trials
(verapamil)
Recent Studies (post-2010) (verapamil)
70117,6211,5272,067

Protein Interaction Comparison

ProteinTaxonomyge 68 (IC50)verapamil (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)6.8
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.297
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
ATP-dependent translocase ABCB1Homo sapiens (human)2.2346
Cytochrome P450 3A4Homo sapiens (human)3.8008
Alpha-2A adrenergic receptorHomo sapiens (human)0.579
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)3.02
ATP-dependent translocase ABCB1Mus musculus (house mouse)10
Catechol O-methyltransferaseHomo sapiens (human)0.2
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)8
Histamine H2 receptorHomo sapiens (human)2.59
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.442
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.297
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)3.02
Sodium-dependent serotonin transporterHomo sapiens (human)0.24
Multidrug resistance-associated protein 1 Homo sapiens (human)5.598
D(3) dopamine receptorHomo sapiens (human)0.186
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.165
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)6.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.2
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.3945
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.2
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.175
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.1934

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burghofer, S; Chiba, P; Ecker, G; Moser, A; Richter, E; Tell, B1
Chiba, P; Cordes, HP; Csöllei, J; Ecker, G; Hitzler, M; Schaper, KJ; Schmid, D; Seydel, JK; Visser, K1

Other Studies

2 other study(ies) available for ge 68 and verapamil

ArticleYear
Synthesis, pharmacologic activity, and structure-activity relationships of a series of propafenone-related modulators of multidrug resistance.
    Journal of medicinal chemistry, 1995, Jul-07, Volume: 38, Issue:14

    Topics: Daunorubicin; Drug Resistance, Multiple; Drug Synergism; Etoposide; Humans; Magnetic Resonance Spectroscopy; Propafenone; Structure-Activity Relationship; Tumor Cells, Cultured

1995
Structure-activity relationship studies on benzofuran analogs of propafenone-type modulators of tumor cell multidrug resistance.
    Journal of medicinal chemistry, 1996, Nov-22, Volume: 39, Issue:24

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzofurans; Calorimetry, Differential Scanning; Cells, Cultured; Daunorubicin; Drug Resistance, Multiple; Ethanolamines; Liposomes; Magnetic Resonance Spectroscopy; Membranes, Artificial; Propafenone; Regression Analysis; Rhodamine 123; Rhodamines; Structure-Activity Relationship

1996