Page last updated: 2024-08-16

gatifloxacin and pyrazinamide

gatifloxacin has been researched along with pyrazinamide in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (25.00)	29.6817
2010's	13 (65.00)	24.3611
2020's	2 (10.00)	2.80

Authors

Authors	Studies
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Feng, LS; Gao, C; Hu, YQ; Lv, ZS; Wu, X; Xu, Z; Zhang, S; Zhao, F	1
Dhawan, S; Girase, PS; Karpoormath, R; Kumar, V; Palkar, MB; Shinde, SR	1
Kubendiran, G; Mitchison, DA; Paramasivan, CN; Sulochana, S	1
Fourie, PB; Horton, J; Kanyok, TP; McIlleron, H; Norman, J; Smith, PJ	1
Krinke, GJ; Wells, MY	1
Allen, J; Coleman, DJ; Davies, GR; Fourie, B; Kanyok, T; Levin, J; Lienhardt, C; Mitchison, DA; Mthiyane, T; Reddy, C; Rustomjee, R; Sirgel, FA; Sturm, AW	1
Ambrose, PG; Bhavnani, SM; Caws, M; Chau, TT; Dung, NT; Farrar, J; Hammel, JP; Hien, TT; Kulawy, R; Mai, PP; Reynolds, DK; Thwaites, GE; Török, ME; Van Wart, SA	1
Bah-Sow, O; Gninafon, M; Horton, J; Lienhardt, C; Lo, MB; McIlleron, H; Merle, CS; Olliaro, PL; Rustomjee, R; Simonsson, US; Smith, P; Smythe, W	1
Aung, KJ; Das, PK; Declercq, E; Hossain, MA; Rieder, HL; Sarker, MR; Van Deun, A	1
Boukary, I; Daouda, M; Hanki, Y; Harouna, SH; Morou, S; Piubello, A; Souleymane, MB; Van Deun, A	1
Amukoye, E; Bah, B; de Jong, BC; Fielding, K; Gninafon, M; Horton, J; Kassa, F; Lapujade, O; Lienhardt, C; Lo, MB; Merle, CS; Mthiyane, T; N'Diaye, A; Odhiambo, J; Olliaro, PL; Perronne, C; Rustomjee, R; Sismanidis, C; Sow, OB	1
Abena Foe, JL; Aït-Khaled, N; Kuaban, C; Noeske, J; Rieder, HL; Trébucq, A	1
Alvarez-Uria, G; Midde, M	1
Deshpande, D; Gumbo, T; Magombedze, G; McIlleron, H; Merle, CS; Olliaro, PL; Pasipanodya, JG; Smythe, W	1
Chen, H; Chen, N; Huang, C; Li, Y; Nie, Q; Tang, Q; Tao, L; Wang, X; Wang, Y; Yang, C; Zhou, Y	1

Reviews

2 review(s) available for gatifloxacin and pyrazinamide

Article	Year
Isoniazid derivatives and their anti-tubercular activity. European journal of medicinal chemistry, 2017, Jun-16, Volume: 133 Topics: Animals; Antitubercular Agents; Drug Discovery; Humans; Isoniazid; Mycobacterium tuberculosis; Tuberculosis; Tuberculosis, Multidrug-Resistant	2017
An appraisal of anti-mycobacterial activity with structure-activity relationship of piperazine and its analogues: A review. European journal of medicinal chemistry, 2021, Jan-15, Volume: 210 Topics: Animals; Antitubercular Agents; Drug Design; Drug Discovery; Humans; Mycobacterium tuberculosis; Piperazine; Structure-Activity Relationship; Tuberculosis	2021

Trials

5 trial(s) available for gatifloxacin and pyrazinamide

Article	Year
A Phase II study of the sterilising activities of ofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2008, Volume: 12, Issue:2 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antitubercular Agents; Aza Compounds; Colony Count, Microbial; Drug Therapy, Combination; Female; Fluoroquinolones; Gatifloxacin; Humans; Isoniazid; Male; Middle Aged; Moxifloxacin; Nonlinear Dynamics; Ofloxacin; Pyrazinamide; Quinolines; Rifampin; Sputum	2008
Randomized pharmacokinetic and pharmacodynamic comparison of fluoroquinolones for tuberculous meningitis. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:7 Topics: Administration, Oral; Adolescent; Adult; Aged; Ciprofloxacin; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Injections, Intramuscular; Isoniazid; Levofloxacin; Male; Middle Aged; Multivariate Analysis; Ofloxacin; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Meningeal; Young Adult	2011
Evaluation of initial and steady-state gatifloxacin pharmacokinetics and dose in pulmonary tuberculosis patients by using monte carlo simulations. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:9 Topics: Adult; Antitubercular Agents; Area Under Curve; Coinfection; Drug Administration Schedule; Drug Dosage Calculations; Drug Synergism; Drug Therapy, Combination; Female; Fluoroquinolones; Gatifloxacin; HIV Infections; Humans; Isoniazid; Male; Monte Carlo Method; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary	2013
A four-month gatifloxacin-containing regimen for treating tuberculosis. The New England journal of medicine, 2014, Oct-23, Volume: 371, Issue:17 Topics: Adult; Antitubercular Agents; Blood Glucose; Drug Administration Schedule; Drug Therapy, Combination; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Intention to Treat Analysis; Isoniazid; Male; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary	2014
Artificial intelligence-derived 3-Way Concentration-dependent Antagonism of Gatifloxacin, Pyrazinamide, and Rifampicin During Treatment of Pulmonary Tuberculosis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018, 11-28, Volume: 67, Issue:suppl_3 Topics: Adolescent; Adult; Antitubercular Agents; Artificial Intelligence; Dose-Response Relationship, Drug; Female; Gatifloxacin; Humans; Male; Middle Aged; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Young Adult	2018

Other Studies

13 other study(ies) available for gatifloxacin and pyrazinamide

Article	Year
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Moxifloxacin and gatifloxacin in an acid model of persistent Mycobacterium tuberculosis. Journal of chemotherapy (Florence, Italy), 2006, Volume: 18, Issue:6 Topics: Antitubercular Agents; Aza Compounds; Colony Count, Microbial; Drug Synergism; Fluoroquinolones; Gatifloxacin; Hydrogen-Ion Concentration; Isoniazid; Moxifloxacin; Mycobacterium tuberculosis; Pyrazinamide; Quinolines; Rifampin; Time Factors	2006
Elevated gatifloxacin and reduced rifampicin concentrations in a single-dose interaction study amongst healthy volunteers. The Journal of antimicrobial chemotherapy, 2007, Volume: 60, Issue:6 Topics: Aged; Antibiotics, Antitubercular; Area Under Curve; Cross-Over Studies; Drug Interactions; Female; Fluoroquinolones; Gatifloxacin; Humans; Isoniazid; Male; Middle Aged; Pyrazinamide; Rifampin	2007
Cerebral vacuolation induced in rats by the administration of LUP-3FDC, an anti-tuberculosis cocktail. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2008, Volume: 59, Issue:6 Topics: Administration, Oral; Animals; Antitubercular Agents; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluoroquinolones; Gatifloxacin; Isoniazid; Male; Microscopy, Electron; Pyrazinamide; Rats; Rats, Wistar; Rifampin; Toxicity Tests, Chronic; Ultrasonography; Vacuoles	2008
Successful '9-month Bangladesh regimen' for multidrug-resistant tuberculosis among over 500 consecutive patients. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2014, Volume: 18, Issue:10 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bangladesh; Child; Clofazimine; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Follow-Up Studies; Gatifloxacin; Humans; Kanamycin; Logistic Models; Male; Middle Aged; Multivariate Analysis; Mycobacterium tuberculosis; Prospective Studies; Pyrazinamide; Risk Factors; Sputum; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult	2014
High cure rate with standardised short-course multidrug-resistant tuberculosis treatment in Niger: no relapses. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2014, Volume: 18, Issue:10 Topics: Adolescent; Adult; Aged; Body Mass Index; Body Weight; Clofazimine; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Multiple, Bacterial; Ethambutol; Female; Fluoroquinolones; Follow-Up Studies; Gatifloxacin; HIV Infections; Humans; Kanamycin; Male; Middle Aged; Niger; Prospective Studies; Pyrazinamide; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult	2014
High effectiveness of a 12-month regimen for MDR-TB patients in Cameroon. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2015, Volume: 19, Issue:5 Topics: Adolescent; Adult; Aged; Antitubercular Agents; Cameroon; Clofazimine; Cohort Studies; Confidence Intervals; Developing Countries; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Ethambutol; Female; Fluoroquinolones; Gatifloxacin; Humans; Isoniazid; Kanamycin; Male; Medication Adherence; Middle Aged; Odds Ratio; Prospective Studies; Prothionamide; Pyrazinamide; Risk Assessment; Time Factors; Treatment Outcome; Tuberculosis, Multidrug-Resistant; Young Adult	2015
Sex differences and factors influencing the duration of the QT interval in patients on anti-tuberculosis therapy. The European respiratory journal, 2018, Volume: 51, Issue:2 Topics: Antitubercular Agents; Clinical Trials as Topic; Electrocardiography; Ethambutol; Female; Gatifloxacin; Heart Rate; Humans; Isoniazid; Male; Models, Theoretical; Multivariate Analysis; Pyrazinamide; Rifampin; Sex Factors; Tuberculosis	2018
High-dose gatifloxacin-based shorter treatment regimens for MDR/RR-TB. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022, Volume: 115 Topics: Antitubercular Agents; Gatifloxacin; Humans; Isoniazid; Pyrazinamide; Treatment Outcome; Tuberculosis, Multidrug-Resistant	2022