Page last updated: 2024-09-03

gastrodin and glutamic acid

gastrodin has been researched along with glutamic acid in 10 studies

Compound Research Comparison

Studies
(gastrodin)
Trials
(gastrodin)
Recent Studies (post-2010)
(gastrodin)
Studies
(glutamic acid)
Trials
(glutamic acid)
Recent Studies (post-2010) (glutamic acid)
302323441,75745212,876

Protein Interaction Comparison

ProteinTaxonomygastrodin (IC50)glutamic acid (IC50)
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2Rattus norvegicus (Norway rat)0.821
Chain A, Glutamate Receptor Subunit 2Rattus norvegicus (Norway rat)0.821
Chain B, Glutamate Receptor Subunit 2Rattus norvegicus (Norway rat)0.821
Metabotropic glutamate receptor 8Homo sapiens (human)0.0057
Glutamate receptor ionotropic, NMDA 2DHomo sapiens (human)0.07
Glutamate receptor ionotropic, NMDA 3BHomo sapiens (human)0.07
Glutamate receptor 1Rattus norvegicus (Norway rat)0.5885
Glutamate receptor 2Rattus norvegicus (Norway rat)0.5885
Glutamate receptor 3Rattus norvegicus (Norway rat)0.5885
Glutamate receptor 4Rattus norvegicus (Norway rat)0.5885
Glutamate receptor ionotropic, kainate 1Rattus norvegicus (Norway rat)0.38
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)0.1533
Glutamate receptor ionotropic, kainate 2Rattus norvegicus (Norway rat)0.38
Glutamate receptor 1Homo sapiens (human)0.613
Glutamate receptor 2Homo sapiens (human)0.613
Glutamate receptor 3Homo sapiens (human)0.613
Glutamate receptor ionotropic, kainate 3Rattus norvegicus (Norway rat)0.38
Excitatory amino acid transporter 1Homo sapiens (human)207
Glutamate receptor 4Homo sapiens (human)0.613
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.1533
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.1533
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.1533
Glutamate receptor ionotropic, kainate 4Rattus norvegicus (Norway rat)0.38
Glutamate receptor ionotropic, NMDA 1Homo sapiens (human)0.07
Glutamate receptor ionotropic, NMDA 2AHomo sapiens (human)0.07
Glutamate receptor ionotropic, NMDA 2BHomo sapiens (human)0.07
Glutamate receptor ionotropic, NMDA 2CHomo sapiens (human)0.07
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.1533
Glutamate receptor ionotropic, kainate 5Rattus norvegicus (Norway rat)0.38
Glutamate receptor ionotropic, NMDA 3AHomo sapiens (human)0.07
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.1533
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.1533

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's5 (50.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Zeng, X; Zhang, K; Zhang, L; Zhang, S; Zheng, X1
Zeng, X; Zhang, S; Zhang, Y; Zheng, X1
Bie, X; Lu, Y; Xu, X1
Gao, YS; Liu, W; Song, SW; Su, BL; Wang, ZS; Zhang, X1
Hu, Y; Jiang, G; Li, J; Li, Q; Wu, H1
Chen, A; Li, S; Ma, J; Wang, C; Wang, X; Xin, Z; Zhang, J1
Li, Q; Liao, XY; Liu, XJ; Liu, YD; Lu, D; Mu, ZH; Qi, YH; Qian, ZY; Wan, Q; Wang, Q; Wang, X; Yang, ZH; Zhang, MY; Zhu, R; Zou, YY1
Huang, Y; Long, H; Ruan, J; Wang, C; Zhang, M1
Cheng, H; Chu, J; Jiang, T; Li, Q; Su, J; Wang, Q; Wang, X1
Chang, CY; Chen, MF; Chiou, TW; Chiu, IM; Harn, HJ; Ho, TJ; Li, X; Lin, SZ; Liu, CA; Su, HL; Ting, HC; Tsai, YJ; Yang, HI1

Other Studies

10 other study(ies) available for gastrodin and glutamic acid

ArticleYear
A study of the neuroprotective effect of the phenolic glucoside gastrodin during cerebral ischemia in vivo and in vitro.
    Planta medica, 2006, Volume: 72, Issue:15

    Topics: Animals; Benzyl Alcohols; Brain Ischemia; Cell Hypoxia; Chromatography, High Pressure Liquid; Gastrodia; Glucosides; Glutamic Acid; Hippocampus; Male; Neuroprotective Agents; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhizome

2006
A microdialysis study of effects of gastrodin on neurochemical changes in the ischemic/reperfused rat cerebral hippocampus.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:4

    Topics: Animals; Benzyl Alcohols; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Extracellular Space; gamma-Aminobutyric Acid; Glucosides; Glutamic Acid; Hippocampus; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Ischemic Attack, Transient; Male; Microdialysis; Neurons; Neuroprotective Agents; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors

2007
Protective effects of gastrodin on hypoxia-induced toxicity in primary cultures of rat cortical neurons.
    Planta medica, 2007, Volume: 73, Issue:7

    Topics: Animals; Benzyl Alcohols; Brain Ischemia; Cell Hypoxia; Cerebral Cortex; Chromatography, High Pressure Liquid; Gastrodia; Glucosides; Glutamic Acid; Neuroprotective Agents; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhizome

2007
Gastrodin improved baroreflex sensitivity and increased gamma-amino butyric acid content in brains without decreasing blood pressure in spontaneously hypertensive rats.
    CNS neuroscience & therapeutics, 2012, Volume: 18, Issue:10

    Topics: Animals; Baroreflex; Benzyl Alcohols; Blood Pressure; Brain; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glucosides; Glutamic Acid; Mass Spectrometry; Rats; Rats, Inbred SHR

2012
Gastrodin inhibits glutamate-induced apoptosis of PC12 cells via inhibition of CaMKII/ASK-1/p38 MAPK/p53 signaling cascade.
    Cellular and molecular neurobiology, 2014, Volume: 34, Issue:4

    Topics: Animals; Apoptosis; Benzyl Alcohols; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Survival; Cytochromes c; Glucosides; Glutamic Acid; MAP Kinase Kinase Kinase 5; Membrane Potential, Mitochondrial; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Rats; Signal Transduction; Tumor Suppressor Protein p53

2014
Effect of Gastrodin on Early Brain Injury and Neurological Outcome After Subarachnoid Hemorrhage in Rats.
    Neuroscience bulletin, 2019, Volume: 35, Issue:3

    Topics: Animals; Apoptosis; Astrocytes; Benzyl Alcohols; Blood-Brain Barrier; Brain; Brain Edema; Calcium; Glucosides; Glutamic Acid; Male; Microglia; Neurons; Neuroprotective Agents; Oxidative Stress; Rats, Sprague-Dawley; Subarachnoid Hemorrhage

2019
Early intervention with gastrodin reduces striatal neurotoxicity in adult rats with experimentally‑induced diabetes mellitus.
    Molecular medicine reports, 2019, Volume: 19, Issue:4

    Topics: Animals; Benzyl Alcohols; Biomarkers; Brain-Derived Neurotrophic Factor; Corpus Striatum; Diabetes Mellitus, Experimental; Gene Expression; Glucosides; Glutamic Acid; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Neurons; Rats; Receptor, trkB

2019
Gastrodin alleviates Tourette syndrome via Nrf-2/HO-1/HMGB1/NF-кB pathway.
    Journal of biochemical and molecular toxicology, 2019, Volume: 33, Issue:10

    Topics: Animals; Benzyl Alcohols; Corpus Striatum; Cytokines; gamma-Aminobutyric Acid; Glucosides; Glutamic Acid; Heme Oxygenase-1; HMGB1 Protein; Male; Malondialdehyde; NF-E2-Related Factor 2; NF-kappa B; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tourette Syndrome

2019
Gastrodin protects against glutamate-induced ferroptosis in HT-22 cells through Nrf2/HO-1 signaling pathway.
    Toxicology in vitro : an international journal published in association with BIBRA, 2020, Volume: 62

    Topics: Animals; Benzyl Alcohols; Cell Line; Ferroptosis; Gastrodia; Glucosides; Glutamic Acid; Heme Oxygenase-1; L-Lactate Dehydrogenase; Lipid Peroxidation; Membrane Proteins; Mice; Neurons; NF-E2-Related Factor 2; Protective Agents; Reactive Oxygen Species; Signal Transduction; Translocation, Genetic

2020
Coactivation of GSK3β and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons.
    Cells, 2021, 10-16, Volume: 10, Issue:10

    Topics: Amyotrophic Lateral Sclerosis; Animals; Axons; Benzyl Alcohols; Calcium; Cell Differentiation; Glucosides; Glutamic Acid; Glycogen Synthase Kinase 3 beta; Humans; Induced Pluripotent Stem Cells; Insulin-Like Growth Factor I; MAP Kinase Signaling System; Mice, Transgenic; Motor Neurons; Mutation; Nerve Degeneration; Nerve Fibers; Neurites; Superoxide Dismutase-1; Survival Analysis

2021