gastrodin has been researched along with glucose, (beta-d)-isomer in 271 studies
| Studies (gastrodin) | Trials (gastrodin) | Recent Studies (post-2010) (gastrodin) | Studies (glucose, (beta-d)-isomer) | Trials (glucose, (beta-d)-isomer) | Recent Studies (post-2010) (glucose, (beta-d)-isomer) |
|---|---|---|---|---|---|
| 302 | 3 | 234 | 21,956 | 883 | 10,747 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (4.80) | 18.7374 |
| 1990's | 10 (3.69) | 18.2507 |
| 2000's | 36 (13.28) | 29.6817 |
| 2010's | 155 (57.20) | 24.3611 |
| 2020's | 57 (21.03) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, Z; Tan, T; Wu, C; Zhong, Y | 1 |
| Li, L; Zhu, Q | 1 |
| Li, JS; Li, JX; Wang, YZ; Wu, QA; Zhu, JH | 1 |
| Huang, JH | 1 |
| Huang, JH; Wang, GL | 1 |
| Gan, ZJ | 1 |
| Huang, XF | 1 |
| Chu, DQ; Huang, J; Lu, GW; Mo, QZ; Ye, DY; Zou, YJ | 1 |
| Huang, ZL | 1 |
| Hu, GC; Yang, Q | 1 |
| Chen, YR; Han, GZ; Liu, KX; Su, CY; Tang, NY; Zhang, YL | 1 |
| Chang, YL; Chen, YR; Han, GZ; Liu, KX; Su, CY; Tang, NY | 1 |
| Chi, XP; Li, TL; Lu, B; Luo, R; Wang, BN | 1 |
| Yang, Q | 1 |
| Lu, GW; Mo, QZ; Zou, YJ | 1 |
| He, S; Kuang, A; Tan, T; You, J; Zhong, Y | 1 |
| Chang, YS; Chen, CF; Hsieh, MT; Huang, SC; Peng, WH; Wu, CR | 1 |
| Chen, CF; Hsieh, MT; Wu, CR | 1 |
| Su, J; Wang, B | 1 |
| Ahn, EM; Baek, NI; Bahn, JH; Cho, SW; Choi, SY; Jeon, SG; Kim, YK; Lee, BR; Park, JK; Shon, IH | 1 |
| Guo, H; Luo, H; Xiao, J; Yuan, S | 1 |
| Pan, R; Xu, J | 1 |
| An, SJ; Baek, NI; Choi, SY; Hwang, IK; Jung, SJ; Kang, TC; Kim, SK; Kwon, OS; Lee, HY; Park, SK; Won, MH | 1 |
| Liu, N; Long, Q; Wu, Y | 1 |
| Hu, SL; Huang, SY; Shi, JG; Yang, YC | 1 |
| Chen, F; Li, HB | 1 |
| Feng, GF; Hu, HT; Liu, ZH; Mao, NY; Zhao, ZY | 1 |
| Deng, L; Gong, T; He, LL; Li, LL; Zhang, ZR | 1 |
| Li, K; Liu, F; Liu, Y; Pei, J; Tang, X; Zhang, L | 1 |
| Fu, TX; Hu, WX; Liu, SP; Luo, ZY; Shu, XS; Tao, J; Tao, Y; Wang, ZC; Wen, L | 1 |
| Gong, JS; Ma, WP; Pu, JX; Xiao, CJ; Xu, SG; Zheng, SQ | 2 |
| Zeng, X; Zhang, K; Zhang, L; Zhang, S; Zheng, X | 1 |
| Huang, GH; Li, LJ; Xi, YW | 1 |
| Huang, JX; Ma, ZY; Song, JR; Yang, MY; Zhang, J; Zhu, HL | 1 |
| Bie, X; Chen, Y; Dai, H; Han, J; Wan, H; Zhao, T | 1 |
| Zeng, X; Zhang, S; Zhang, Y; Zheng, X | 1 |
| Chen, YF; Lin, LC; Tsai, TH; Tsai, TR | 1 |
| Chen, G; Wang, Q; Zeng, S | 2 |
| Dai, Z; Lin, B; Ma, B; Qin, J; Wang, G; Zhou, X | 1 |
| Bie, X; Lu, Y; Xu, X | 1 |
| Heng, MY; Hew, CS; Hong Yong, JW; Koh, H; Ong, ES; Tan, SN; Teo, CC | 1 |
| Sheng, YX; Sun, SQ; Xu, JT; Zhang, JL; Zhang, W | 1 |
| Hew, CS; Ong, ES; Tan, SN; Teo, CC; Yong, JW | 1 |
| Cai, Z; Hou, S; Li, Y; Pu, J; Xu, S; Yang, Z; Zhao, B | 1 |
| Sheng, YX; Zhang, JL; Zhang, W | 1 |
| Liu, J; Ye, YH; Yu, ZB; Zhou, YW | 1 |
| Cai, Z; Chen, QH; Hou, SX; Li, YB; Song, XR; Yang, ZX; Zhao, BB | 1 |
| Cai, Z; Hou, SX; Song, XR; Yang, ZX; Zhao, BB; Zheng, Y | 1 |
| Yang, YM; Yu, GY; Zhang, Q | 1 |
| Fu, L; Gao, Y; Li, LC; Liu, L; Mao, YH; Wang, ZP | 1 |
| Chen, YF; Lee, WC; Lin, LC; Tsai, TH; Wu, YT | 1 |
| Hu, WX; Liu, RX; Liu, SP; Luo, ZY; Msangi, CI; Shu, XS; Tao, J; Wen, L; Zhou, CQ | 1 |
| Chen, JT; Chen, L; Hu, P; Li, CC; Ruan, DY; Wang, HL; Wang, M; Wang, S; Xing, TR; Yong, W | 1 |
| Du, X; Li, Y; Liu, Y; Mao, R; Shan, Y | 1 |
| Cheng, F; Fang, YX; Zhang, K; Zhao, SQ; Zheng, J | 1 |
| Feng, Y; Hong, YL; Li, JS; Lin, X; Xu, DS; Zhang, YJ | 1 |
| Li, A; Liu, F; Lv, H; Ma, H; Yao, B | 1 |
| Bai, ZQ; Hu, CF; Sun, LP | 1 |
| Cui, X; Guo, DM; Ju, XH; Liu, N; Shi, Y | 1 |
| Chen, C; Chen, E; Cui, Y; Dai, P; Han, W; Zhang, W; Zhu, H | 1 |
| Ma, P; Xu, Y; Yao, S; Zhan, M; Zhang, S; Zhang, Y; Zhang, Z | 1 |
| Wang, XD; Zeng, S | 1 |
| Choi, DK; Koppula, S; Suk, K | 1 |
| Chen, Y; Du, P; Han, FM; Yang, Y | 1 |
| Hu, PY; Wu, B; Wu, ZF; Yang, M; Yue, PF; Zheng, Q | 1 |
| Ai, QL; Bian, LG; Dai, JN; Li, YM; Liu, YD; Lu, D; Sun, J; Zhang, W; Zhong, LM; Zong, Y | 1 |
| Bian, Z; Chen, C; Dai, J; Dong, X; Guo, H; Shu, C; Tang, Q; Zhang, DP; Zhang, Y; Zhou, H; Zong, J | 1 |
| Feng, Y; Lin, X; Wei, Y; Zhang, N | 1 |
| Cai, Z; Hou, S; Liu, Z; Song, X; Sun, F; Yang, Z | 1 |
| Cao, YX; Fan, WJ; Lü, SM; Luo, GG; Xu, CB; Yuan, BB; Yuan, XY | 1 |
| Duan, JH; Han, WJ; Hu, SJ; Luo, C; Miao, B; Sun, W; Wang, WT; Wang, XC; Ye, X | 1 |
| Gao, YS; Liu, W; Song, SW; Su, BL; Wang, ZS; Zhang, X | 1 |
| Cui, C; Guan, H; Jiang, H; Tian, S; Wang, L; Wang, X; Yang, D; Zhang, S; Zhu, L | 1 |
| Dong, M; Fan, L; Guo, H; Li, G; Li, X; Xu, H; Zhang, X; Zhao, X; Zou, Y | 1 |
| Bian, X; Liu, Y; Xu, J; Yu, T; Zhang, Y | 1 |
| Dai, J; Du, Q; Huang, Z; Jiang, L; Lin, J; Wang, Y | 1 |
| Chen, YL; Gui, L; Guo, JZ; Han, Y; Lu, D; Song, R; Sun, J; Sun, L; Xie, YN; Yang, P | 1 |
| Cai, Z; Huang, J; Lei, X; Liu, Z; Luo, H; Mai, Y; Yang, Z | 1 |
| Chen, Q; Dong, Y; Fan, L; Xu, T; Zhang, H | 1 |
| He, WY; Ji, XY; Jiang, JD; Li, YH; Li, ZR; Ma, LL; Wang, B; Wang, HQ; Xue, ST; Zhang, T; Zheng, GH | 1 |
| Bhandary, B; Chae, HJ; Chae, SW; Han, SY; Jo, KS; Kim, DS; Kim, HR; Kim, MG; Kim, SY; Lee, BH; Lee, GH; Seo, HN; So, BO | 1 |
| Shu, G; Su, H; Wang, C; Xiang, M; Yang, T | 1 |
| Qian, J; Zhang, L; Zhang, W; Zhu, Y | 1 |
| Liu, YH; Xu, DQ; Zhou, JJ | 1 |
| Liu, XQ; Yuan, QY | 2 |
| Fu, Q; Liu, X; Wang, Y; Wu, Z | 1 |
| Jiang, SX | 1 |
| Chen, Y; Nie, H; Peng, Z; Tan, Q; Wang, H; Wang, Y; Wu, D; Xue, F; Zhang, R | 1 |
| Chen, Y; Peng, Z; Tan, Q; Wang, H; Wang, Y; Xue, F; Zhang, R | 1 |
| Nie, H; Peng, Z; Qiao, Y; Tan, Q; Wang, H; Wang, Y; Xue, F; Zhang, R; Zhang, Z | 1 |
| Hu, Y; Jiang, G; Li, J; Li, Q; Wu, H | 1 |
| Hu, WP; Liu, TT; Qiu, CY; Qiu, F; Qu, ZW; Yang, Z | 1 |
| Hu, Y; Li, C; Shen, W | 1 |
| Chen, L; Gao, Q; Geng, Y; Huang, L; Ji, W; Ma, X; Wang, X | 1 |
| Li, Y; Wang, A; Wang, X; Yan, S; Zhang, F | 1 |
| Cai, J; Hu, Y; Jiang, G; Li, Q; Liu, L; Peng, C | 1 |
| Li, C; Li, YR; Wang, ZM; Yang, LX | 1 |
| Jia, Y; Kong, L; Li, X; Liu, Q; Luo, J; Shen, J; Wang, J; Wang, KD; Xie, H | 2 |
| Xu, DQ; Zhou, JJ | 1 |
| Dong, MX; Hong, B; Li, XM; Wang, XL; Xing, GH; Zhang, XJ; Zou, Y | 1 |
| Gong, XJ; Kang, ZJ; Zhao, Y; Zhou, X | 1 |
| Huang, TX; Liang, P; Zhang, JM; Zhao, XM; Zhu, R | 1 |
| Li, A; Zhang, F | 2 |
| Chen, Z; Lin, Y; Liu, X; Wang, S; Yang, C; Yang, R | 1 |
| Chen, S; Fang, H; Li, J; Peng, H; Qiu, B; Wang, Z; Yang, E; Zheng, H; Zhou, J | 1 |
| Li, LJ; Yan, R | 1 |
| Chen, PZ; Chen, Y; Hu, B; Ji, WG; Jiang, HH; Ren, SC; Wen, B; Xu, F; Zhang, J; Zhu, ZR | 1 |
| Li, YY; Wang, YY; Xie, Q; Xie, YM; Yang, W; Zhao, W; Zhuang, Y | 1 |
| Fan, J; Fan, JZ; Gao, B; Han, YH; Huang, Q; Li, XJ; Liu, J; Luo, ZJ; Shi, J; Yang, L; Zhang, HY; Zhang, JK | 1 |
| Cai, M; Chen, G; Deng, J; Hai, C; Liu, J; Liu, R; Peng, Z; Tan, Q; Wang, S; Zhang, T | 1 |
| Chi, XF; Dong, Q; Hu, FZ; Tan, L; Xiao, YC | 1 |
| Tan, Y; Wang, X; Zhang, F | 1 |
| Liu, JJ; Ma, HH; Wang, X; Xie, YL; Zhou, M | 1 |
| Cheng, M; Li, J; Liu, X; Tang, C; Wang, L; Xiao, H | 1 |
| He, Y; Li, W; Lin, Y; Weng, W; Xu, H; Yang, H; Zhang, S; Zheng, H; Zhou, Z; Zhu, L | 1 |
| Jiang, L; Wang, YR; Xu, GL; Yan, XJ; Yu, LB; Zhang, QY | 1 |
| Dong, Z; Lu, XQ; Xia, YP; Zheng, YY; Zhu, SB | 1 |
| Cheng, M; Liu, X; Tang, C; Wang, L; Xiao, H | 1 |
| Cheng, M; Liu, X; Qu, Y; Tang, C; Wang, L; Xiao, H | 1 |
| Ge, M; He, H; Li, N; Li, Y; Shao, RG; Yu, B; Zhao, S; Zhen, Y | 1 |
| Huang, Y; Jin, H; Sun, W; Sun, Y | 1 |
| Huang, L; Ji, W; Liu, J; Wang, D; Wang, X; Zhang, M | 1 |
| Jiang, JD; Jiang, WX; Kong, WJ; Li, Z; Qu, LL; Yu, B | 1 |
| Guo, HL; Han, J; Liu, SB; Tian, Z; Wang, XS; Zhang, N; Zhao, MG | 1 |
| Chen, C; Du, JR; Long, FY; Mao, XN; Wan, JY; Wang, PH; Zhang, L; Zhang, S; Zhao, LX | 1 |
| Bai, Y; Bi, H; Liu, T; Ma, Y; Yin, H; Zhuang, Y | 1 |
| Li, Y; Zhang, Z | 1 |
| Jin, X; Li, L; Li, P; Liu, J; Sun, P; Wang, X; Zhang, D | 1 |
| Li, HB; Miao, HC; Wu, F; Xiong, KR; Zhu, XL | 1 |
| Chen, WC; Ho, CT; Lai, YS; Lin, SH; Lin, YE; Lu, KH; Panyod, S; Sheen, LY | 1 |
| Chiang, TY; Chiang, YC; Chou, CH; Huang, CY; Li, SJ; Tsai, CC; Wu, KM | 1 |
| Deng, JB; Guo, JN; He, WY; Liang, HM; Wang, Q; Zhang, JS; Zhou, SF | 1 |
| Chen, WC; Ho, CT; Lai, YS; Lin, SH; Lin, YE; Panyod, S; Sheen, LY | 1 |
| Li, M; Qian, S | 1 |
| Ding, J; Huang, R; Li, HB; Miao, HC; Wu, F; Xiong, KR; Zhao, J | 1 |
| Fan, YX; Jin, CC; Li, HJ; Li, P; Ma, XD; Wang, F; Xin, GZ | 1 |
| Hung, WC; Min, MY; Wong, SB | 1 |
| Hu, PY; Liu, D; Wu, B; Yang, M; Yue, PF; Zhang, GS; Zheng, Q | 1 |
| Huang, LQ; Kang, L; Lai, CJ; Li, F; Liu, DH; Ma, X; Nan, TG; Yang, J; Yuan, Y; Zha, L; Zhan, ZL | 1 |
| Hahm, DH; Lee, B; Lee, H; Shim, I; Sur, B; Yeom, M | 1 |
| Diao, Y; Du, F; Fang, J; Li, A; Shang, B; Wang, X; Xi, Y | 1 |
| Li, Y; Lou, C; Wang, X | 1 |
| Xu, F; Zhang, K; Zhao, J; Zheng, L; Zuo, W | 1 |
| Cao, XY; Hong, P; Ji, WG; Qi, AP; Shao, H; Yang, Y; Zhu, GX; Zhu, ZR | 1 |
| Deng, Y; Gong, Q; Li, F; Liu, B; Shi, J; Yang, D | 1 |
| Alves, G; Falcão, A; Matias, M; Silvestre, S | 1 |
| Feng, D; Li, X; Li, YJ; Shi, WL; Sun, T; Wang, J; Wang, JB; Wu, YM; Zhao, MG | 1 |
| Liang, P; Zhao, XM; Zhou, NN; Zhu, R | 1 |
| Cao, Z; Dong, H; Han, WJ; Hu, SJ; Lin, Z; Lu, N; Luo, C; Wang, WT; Wu, SX; Xiao, MM; Xie, RG; Zhang, YQ | 1 |
| Chen, L; Liu, X; Qu, M; Wang, H | 1 |
| Gong, X; Jiang, Z; Yan, Y; Zhao, C; Zhao, Y; Zheng, X; Zhou, X | 1 |
| Chen, X; Liu, B; Peng, D; Shen, Y; Wan, L; Zhou, F | 1 |
| Gao, J; Guo, X; Hua, Q; Jia, J; Jing, X; Li, J; Lin, CI; Liu, M; Shi, X | 1 |
| Jiang, X; Liao, C; Song, D; Sun, Y; Zhang, Z; Zhou, J | 1 |
| Hsu, SS; Jan, CR; Liang, WZ | 1 |
| Akerman, S; Goadsby, PJ; Martins-Oliveira, M; Zhao, Y | 1 |
| Hou, J; Li, YJ; Luo, M; Qin, J; Wang, J; Wang, JX; Wang, LM; Wu, LH | 1 |
| Cao, W; Chen, H; Chen, S; Hao, X; Yu, L; Zhang, P; Zhu, D | 1 |
| Chang, S; Feng, B; Guan, J; Wang, L; Zhang, X; Zhao, D; Zhao, T; Zhu, H | 1 |
| Huang, G; Liu, Y | 1 |
| Chen, J; Chen, L; Gu, YT; Guo, WJ; Wang, XY; Wu, CC; Wu, YS; Xiao, J; Xie, JJ; Xuan, J; Yan, YZ; Zhang, XL | 1 |
| Chen, JT; Chung, HH; Huang, B; Shi, SK | 1 |
| Chen, S; Cheng, J; Liu, A; Liu, J; Wang, Y; Zhang, J | 1 |
| Li, B; Li, X; Liu, Y; Yang, Z; Zhu, Q | 1 |
| Huang, F; Ouyang, MA; Song, LY; Wang, Y; Wu, ZJ | 1 |
| Brasil, FB; de Oliveira, MR; Fürstenau, CR | 2 |
| Tang, C; Wu, B; Wu, J; Yu, B; Zhang, Z | 1 |
| Chen, Z; Fang, T; Fu, Q; Liu, S; Mu, S; Yang, L | 1 |
| Cui, Y; Han, L; He, Q; Jin, M; Liu, K; Zhang, S | 1 |
| Li, JJ; Ling, EA; Liu, SJ; Liu, XY | 1 |
| Ding, J; Huang, R; Li, HB; Wu, F; Xiong, KR; Zhao, J | 1 |
| Haddadi, R; Nadi, F; Poursina, M; Zeraati, F | 1 |
| Gao, X; Hao, LL; Huang, CM; Ji, Q; Wang, JW; Zhang, TH | 1 |
| Dong, HJ; Guo, LP; Li, Y; Liu, DH; Mu, Y; Wang, X; Wang, ZW; Zhou, HL | 1 |
| Jiang, JD; Kong, WJ; Wang, C; Yu, B; Zhang, Y | 1 |
| Liang, P; Zhang, JM; Zhao, XM; Zhou, NN; Zhu, R | 1 |
| Liu, ZH; Ma, H; Shi, JG; Wang, L; Wang, WP; Wang, XL; Xu, SF | 1 |
| Chen, A; Chen, L; Fu, S; Liu, H; Tang, L; Tang, Y; Wang, S; Wang, X; Wu, Y; Zhong, Y | 1 |
| de Bittencourt Brasil, F; de Oliveira, MR; Fürstenau, CR | 1 |
| Gui, Y; Guo, J; Li, F; Li, JH; Li, JJ; Li, XH; Liu, SJ; Liu, XY; Wu, CY; Yang, L; Yuan, Y | 1 |
| Dai, BL; Ding, ZS; Jiang, FS; Jin, B; Li, MY; Qian, CD; Yu, HS | 1 |
| Deng, W; Di, S; Liu, D; Qin, M; Yi, B; Zhu, M | 1 |
| Huang, H; Qu, S; Yang, S; Yuan, B; Zeng, Z; Zhang, H | 1 |
| Chen, C; Jiang, ZH; Li, XX; Zhang, XY; Zhou, B | 1 |
| Han, X; He, M; Li, X; Pi, J; Sun, Y; Tian, W; Xu, J; Xu, S; Yu, R | 1 |
| He, S; Meng, X; Sun, G; Sun, X; Wang, R; Ye, T; Zhang, C | 1 |
| Gong, D; Li, Y; Luo, N; Qin, B; Tan, X; Zheng, J; Zheng, W | 1 |
| Chen, A; Li, S; Ma, J; Wang, C; Wang, X; Xin, Z; Zhang, J | 1 |
| Li, L; Xing, Y | 1 |
| He, JY; Li, F; Liu, SY; Liu, ZY; Qiu, CW; Xiao, ZC; Zhang, FL; Zhang, L | 1 |
| Ding, A; Fu, Y; Hu, M; Jiang, Y; Shan, M; Wu, Q; Yan, H; Yao, W; Yu, S; Zhang, L | 1 |
| Ai, Q; Bian, L; Fu, X; Gao, H; Li, S; Lu, D; Sui, Y; Zhang, A; Zhong, L | 1 |
| Hu, J; Ma, Z; Mao, Z; Sun, H | 1 |
| Huang, Y; Long, H; Ruan, J; Wang, C; Zhang, M | 2 |
| Li, Q; Liao, XY; Liu, XJ; Liu, YD; Lu, D; Mu, ZH; Qi, YH; Qian, ZY; Wan, Q; Wang, Q; Wang, X; Yang, ZH; Zhang, MY; Zhu, R; Zou, YY | 1 |
| Jiao, M; Wu, C; Wu, Q; Yin, K; Zhang, T; Zhang, Y; Zhao, X | 1 |
| Cui, X; Hu, Y; Li, Y; Xiong, Y; Zhang, Y; Zhang, Z | 1 |
| Ahmad, O; Cheng, L; Deng, Y; Li, M; Ma, K; Shang, J; Wang, B; Yang, L; Yang, Y; Zhao, J; Zhou, Q | 1 |
| Ai, QL; Bian, LG; Chen, YL; Li, R; Lu, D; Sui, Y; Sun, L; Yang, P; Yao, YY; Zhong, LM | 1 |
| He, Y; Hong, S; Huang, J; Leung, CK; Li, J; Li, L; Li, Z; Yang, G; Zeng, X; Zhang, D | 1 |
| Cao, X; Li, Z; Yan, J; Yang, Z; Zhao, N | 1 |
| Ai, Q; Bian, L; Fu, X; Gao, H; Lu, D; Sui, Y; Yao, Y; Yu, M; Zhang, A; Zhong, L | 1 |
| Bai, H; Fang, K; Guo, X; Lei, H; Ma, Q; Wang, H; Xiong, X | 1 |
| Dong, J; Li, L; Liu, Z; Wang, B; Wang, S; Wang, Y; Zhang, J; Zhang, L | 1 |
| Li, L; Lin, Z; Lu, D; Lu, H; Lyu, L; Sun, L; Sun, W; Yang, P | 1 |
| Cheng, H; Guo, S; Ke, G; Liu, M; Mao, Y; Mi, Y; Wang, M; Wei, P | 1 |
| Ji, XY; Jiang, CR; Li, ZL; Liu, MF; OuYang, B; Zhang, HS | 1 |
| Cheng, H; Chu, J; Jiang, T; Li, Q; Su, J; Wang, Q; Wang, X | 1 |
| Hu, XF; Jin, XP; Ke, SF; Liu, XC; Wang, E; Wang, TL; Wu, CZ; Wu, G | 1 |
| Bai, C; Chen, C; Dai, Z; Du, T; Ji, B; Li, X; Rao, Q; Shi, R; Tian, M; Wang, H; Weng, Z; Xiao, C; Yang, W; Yu, X; Zhang, C; Zheng, CB | 1 |
| Huang, CW; Lai, MC; Liu, PY; Lo, YC; Wu, SN; Yang, CS | 1 |
| Hong, SJ; Li, L; Li, LH; Ma, CL; Xue, FL; Yan, QW; Yang, GM; Yu, Y; Zeng, XF; Zhang, DX; Zhao, YN; Zhou, YQ | 1 |
| Cao, Y; Chen, H; Cheng, H; Chu, J; Jiang, T; Li, Q; Su, J; Tian, S; Wang, X | 1 |
| Dai, M; Li, L; Li, Q; Li, Y; Lu, D; Sun, L; Yang, J; Yu, M; Zheng, M; Zhong, L | 1 |
| Cheng, QQ; He, HY; Liu, X; Tian, MH; Wan, YW; Wang, YC; Yang, WM; Zhang, WD | 1 |
| Gao, YG; Gu, PP; He, ZM; Zang, P; Zhang, ZL; Zhao, Y; Zhu, HY | 1 |
| Cheng, OM; Jiang, QS; Ma, XJ; Qiu, HM; Xiao, H | 1 |
| Liu, CM; Ma, JQ; Ming, QL; Sun, YZ; Tian, ZK; Zhang, YJ | 1 |
| Cui, G; Deng, CK; Huang, YJ; Lei, B; Miao, YH; Mu, ZH; Qian, ZY; Shen, X; Song, JL; Wang, YY; Wu, XY; Zhang, F; Zhang, WQ; Zhang, Y; Zhou, RD; Zou, YY | 1 |
| Ji, H; Li, S; Liu, Y; Lv, H; Zhang, B; Zheng, Y | 1 |
| Ji, LP; Liu, CM; Ma, JQ; Ming, QL; Tian, ZK; Zhang, YJ | 1 |
| Fang, Z; Li, Y; Qian, L; Wang, Y; Wu, L; Yan, S; Zheng, Y | 1 |
| Huang, H; Jin, L; Lin, J; Qu, S; Yang, S; Yuan, B; Zeng, Z; Zhang, H | 1 |
| Cao, H; Chu, L; Lv, Y; Peng, H; Shen, X; Yang, H | 1 |
| Cheng, H; Li, S; Liu, M; Mi, Y; Wang, M | 1 |
| Abdullah, AO; He, J; Liu, Y; Muhammed, FK; Shi, C; Zheng, B | 1 |
| Bao, ZR; Guo, J; Li, F; Li, JJ; Li, LS; Wu, CY; Yang, XK; Yuan, Y; Zhang, XL; Zi, Y | 1 |
| Luo, T; Shu, Y; Wang, M; Wang, Q; Xiao, Z; Xu, S; Yu, C; Yu, S; Yu, T; Zhang, L; Zhang, Q; Zhang, Y; Zhou, L; Zou, J | 1 |
| Bao, H; Chen, L; Wang, W; Wang, X; Wang, Y; Xu, Y; Zhang, Z; Zheng, J | 1 |
| Hu, T; Liu, T; Yin, H; Zhuang, Y | 1 |
| Bian, X; Chen, J; Hu, X; Huang, Y; Nian, S | 1 |
| Chiu, SC; Huang, CW; Lai, MC; Liu, PY; Wu, SN; Yang, CS | 1 |
| Chen, B; Chen, H; Jiang, J; Li, B; Liu, J; Luo, X; Wu, H; Zhang, C; Zhao, B | 1 |
| Li, AY; Wang, Y; Zhao, L | 1 |
| Dong, MX; Li, X; Liu, LK; Xu, TJ | 1 |
| Han, J; Li, Y; Wang, Y; Yang, Y | 1 |
| Chen, TT; Fu, LY; Hu, XX; Li, Y; Shen, XC; Tao, L; Wu, XY; Xiang, Q; Xu, YN; Zhou, X | 1 |
| Jin, S; Liu, F; Qiao, YL; Xiang, WQ | 1 |
| Ji, XY; Liu, MF; Ouyang, B; Zhang, HS | 1 |
| Cai, Z; Guo, K; Huang, B; Lin, Z; Shen, S; Wang, X; Wu, X; Zhao, J | 1 |
| Guo, J; Jiao, J; Lu, D; Pu, Y; Sun, L; Tao, J; Xie, L; Yang, P | 1 |
| Chen, H; Guan, Z; Shao, F; Zhang, Y; Zhou, L | 1 |
| Ai, QL; Guo, JZ; Guo, YJ; Li, R; Lu, D; Yao, YY; Zhao, Y; Zhong, LM | 1 |
| Han, SS; Hou, J; Li, CX; Liu, FY; Pang, WL; Sun, CB; Wang, C; Wen, J; Xing, HJ; Yan, JY; Yang, ZS; Yin, W; Ying, Y; Yuan, JL; Zhang, SQ; Zhou, LC | 1 |
| He, J; Li, X; Li, Y; Lin, X; Liu, Y; Xiu, M; Yang, S | 1 |
| Ding, Y; Fang, Q; Hu, S; Liang, Y; Liu, Z; Tian, S; Wan, J; Yang, D; Yang, L; Zhang, Y | 1 |
| Cheng, O; Jiang, Q; Ma, X; Qiu, H; Wu, K; Xiao, H; Yang, J | 1 |
| Wang, J; Wu, M | 1 |
| Ao, L; Chen, M; Chen, WS; Hsiao, MY; Kung, Y; Liao, WH; Wen, TY; Wu, CH; Yang, SM | 1 |
| Chen, WJ; Fan, XM; Fu, GJ; Gong, X; Guo, CL; Jin, XL; Liao, X; Piao, JZ; Wei, JJ; Yan, Y; Zhang, YL | 1 |
| Chang, CY; Chen, MF; Chiou, TW; Chiu, IM; Harn, HJ; Ho, TJ; Li, X; Lin, SZ; Liu, CA; Su, HL; Ting, HC; Tsai, YJ; Yang, HI | 1 |
| Ma, S; Sun, Y; Yang, Y; Zheng, X | 1 |
| Bai, F; Zhang, N; Zheng, Y | 1 |
| Ao, L; Chen, M; Chen, S; Chen, WS; Feng, X; Liao, C; Liao, Y; Liu, Y; Luo, K; Wang, Y | 1 |
| Huichao, Y; Xiaowei, W; Yanxiang, Z; Yongguang, L | 1 |
| Jiang, L; Liu, H; Liu, R; Nie, P; Tu, Y; Xiong, Y; Xu, G; Yan, X; Zhang, Q; Zhang, W | 1 |
| Li, G; Lin, B; Yang, F; Zhang, K | 1 |
| Chou, AH; Hu, LM; Lee, HC; Liao, CC; Liu, FC; Yu, HP | 1 |
| Fu, M; Hao, K; Li, S; Liu, Y; Yang, Q; Yang, X; Zhou, Z | 1 |
| Chen, AX; Li, HZ; Li, QX; Wang, HX; Wang, JJ; Wang, XX; Xie, ST; Zhang, Q; Zhang, XY; Zhang, YX; Zhou, S; Zhu, JN | 1 |
| Chen, J; Gu, X; Yao, Z; Zhou, Y | 1 |
| Berezutsky, MA; Durnova, NA; Romanteeva, YV | 1 |
| Chen, T; Chen, Y; Li, Y; Shen, X; Tao, L; Xu, Y; Yang, H; Zhang, E | 1 |
| Chen, TT; Chen, Y; Chen, YX; Shen, XC; Tao, L; Wang, DS; Yang, H; Yao, YT | 1 |
7 review(s) available for gastrodin and glucose, (beta-d)-isomer
| Article | Year |
|---|---|
[Recent developments in pharmacological study and clinical application of Gastrodia elata in China].
Topics: Animals; Benzyl Alcohols; Glucosides; Glycosides; Humans; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Plant Extracts; Plants, Medicinal | 1985 |
Inhibitors of microglial neurotoxicity: focus on natural products.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzyl Alcohols; Biological Products; Biphenyl Compounds; Catechin; Catechols; Curcumin; Encephalitis; Fatty Alcohols; Ginsenosides; Glucosides; Microglia; Molecular Structure; Nerve Degeneration; Neuroprotective Agents; Phenyl Ethers; Plant Extracts; Resveratrol; Stilbenes | 2011 |
Gastrodia elata and epilepsy: Rationale and therapeutic potential.
Topics: Anticonvulsants; Benzyl Alcohols; Drugs, Chinese Herbal; Epilepsy; Gastrodia; Glucosides; Humans; Phenols; Phytotherapy; Rhizome | 2016 |
Herbal Compounds with Special Reference to Gastrodin as Potential Therapeutic Agents for Microglia Mediated Neuroinflammation.
Topics: Apigenin; Benzyl Alcohols; Glucosides; Glucuronates; Humans; Inflammation; Isoflavones; Microglia; Neurodegenerative Diseases; Neuroprotective Agents; Plants, Medicinal; Renin-Angiotensin System | 2018 |
[Research progress on mechanism of gastrodin and p-hydroxybenzyl alcohol on central nervous system].
Topics: Benzyl Alcohols; Central Nervous System; Gastrodia; Glucosides; Humans; Plant Extracts | 2020 |
The effects of gastrodin injection on hypertension: A systematic review and meta-analysis.
Topics: Benzyl Alcohols; Blood Pressure; Glucosides; Humans; Hypertension; Injections | 2020 |
[Systematic review and Meta-analysis of efficacy and safety of gastrodin in treatment of tension-type headache].
Topics: Adult; Benzyl Alcohols; Drugs, Chinese Herbal; Glucosides; Humans; Middle Aged; Reproducibility of Results; Tension-Type Headache | 2021 |
3 trial(s) available for gastrodin and glucose, (beta-d)-isomer
| Article | Year |
|---|---|
[Effect of synthetic gastrodin in an injectable form on neurasthenia].
Topics: Adult; Analgesics; Benzyl Alcohols; Clinical Trials as Topic; Double-Blind Method; Female; Glucosides; Glycosides; Humans; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Neurasthenia | 1985 |
[Effects of gastrodin injection on blood pressure and vasoactive substances in treatment of old patients with refractory hypertension: a randomized controlled trial].
Topics: Aged; Aged, 80 and over; Benzyl Alcohols; Blood Pressure; Endothelins; Female; Glucosides; Humans; Hypertension; Infusions, Intravenous; Male; Nitric Oxide; Phytotherapy | 2008 |
Preventive effect of gastrodin on cognitive decline after cardiac surgery with cardiopulmonary bypass: a double-blind, randomized controlled study.
Topics: Adult; Benzyl Alcohols; Cardiopulmonary Bypass; Cardiovascular Surgical Procedures; Cognition Disorders; Double-Blind Method; Female; Glucosides; Heart Valve Prosthesis Implantation; Humans; Male; Middle Aged; Mitral Valve; Young Adult | 2011 |
261 other study(ies) available for gastrodin and glucose, (beta-d)-isomer
| Article | Year |
|---|---|
[Study of the mechanism of gastrodin and derivatives of gastrodigenin].
Topics: Animals; Benzyl Alcohols; Butanols; Glucosides; Hypnotics and Sedatives; Rats; Receptors, GABA-A | 1991 |
[A trial of utilizing TDP (specific electromagnetic wave) in cultivating Gastrodia elata Bl].
Topics: Benzyl Alcohols; Glucosides; Plants, Medicinal; Radiation | 1990 |
[Studies on the quality of Gastrodia elata Bl. cultivated with various kinds of fungus-growing materials].
Topics: Agaricales; Benzyl Alcohols; Drugs, Chinese Herbal; Glucosides; Glycosides; Plants, Medicinal; Trees | 1989 |
[Comparison studies on pharmacological properties of injectio gastrodia elata, gastrodin-free fraction and gastrodin].
Topics: Animals; Autonomic Nervous System; Benzyl Alcohols; Drugs, Chinese Herbal; Glucosides; Glycosides; Heart; Hypnotics and Sedatives; Hypoxia; Mice; Motor Activity | 1989 |
[Studies on some pharmacological effects of gastrodia injection and gastrodin].
Topics: Animals; Benzyl Alcohols; Glucosides; Glycosides; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Mice; Plant Extracts; Plants, Medicinal | 1985 |
[Processing of Gastrodia elata where it is produced].
Topics: Benzyl Alcohols; China; Glucosides; Glycosides; Hot Temperature; Medicine, Chinese Traditional; Plants, Medicinal | 1986 |
[Effect of synthetic gastrodin on the beating and histochemical changes of cultured heart cells of neonatal rats].
Topics: Animals; Benzyl Alcohols; Cells, Cultured; Glucosides; Glycosides; Medicine, Chinese Traditional; Myocardial Contraction; Myocardium; Rats | 1986 |
[Circadian effect on gastrodin pharmacokinetics in rats].
Topics: Animals; Benzyl Alcohols; Circadian Rhythm; Glucosides; Glycosides; Kinetics; Male; Plants, Medicinal; Rats; Rats, Inbred Strains; Tritium | 1986 |
[Effect of sapogenins from the leaves of Panax notoginseng on migraine].
Topics: Adult; Benzyl Alcohols; Double-Blind Method; Female; Ginsenosides; Glucosides; Humans; Male; Middle Aged; Migraine Disorders; Saponins | 1988 |
[Determination of gastrodin in biological specimens and in pharmacokinetics].
Topics: Animals; Benzyl Alcohols; Biological Availability; Chromatography, High Pressure Liquid; Dogs; Female; Glucosides; Glycosides; Male; Rabbits; Rats; Species Specificity; Tissue Distribution | 1987 |
Simultaneous determination of gastrodin and its metabolite by HPLC.
Topics: Animals; Benzyl Alcohols; Bile; Chromatography, High Pressure Liquid; Feces; Glucosides; Glycosides; Liver; Rabbits; Rats | 1987 |
[Study on the stability of gastrodin injection].
Topics: Benzyl Alcohols; Drug Stability; Glucosides; Glycosides; Hydrogen-Ion Concentration; Hydrolysis; Injections | 1986 |
[Kinetic aspects of absorption, distribution, metabolism and excretion of 3H-gastrodin in rats].
Topics: Absorption; Animals; Autoradiography; Benzyl Alcohols; Female; Glucosides; Glycosides; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Mice; Plants, Medicinal; Rats; Rats, Inbred Strains; Tissue Distribution | 1985 |
[Biodistribution and metabolism of 3H-gastrodigenin and 3H-gastrodin in mice].
Topics: Animals; Benzyl Alcohols; Enterohepatic Circulation; Female; Glucosides; Mice; Tissue Distribution | 1994 |
Effects of Gastrodia elata and its active constituents on scopolamine-induced amnesia in rats.
Topics: Amnesia; Animals; Avoidance Learning; Benzyl Alcohols; Drugs, Chinese Herbal; Glucosides; Hypnotics and Sedatives; Male; Memory; Plant Extracts; Rats; Rats, Sprague-Dawley; Scopolamine | 1996 |
Gastrodin and p-hydroxybenzyl alcohol facilitate memory consolidation and retrieval, but not acquisition, on the passive avoidance task in rats.
Topics: Animals; Apomorphine; Avoidance Learning; Benzyl Alcohols; Cycloheximide; Dopamine Agonists; Drugs, Chinese Herbal; Electroshock; Glucosides; Hypnotics and Sedatives; Male; Memory; Muscarinic Antagonists; Nootropic Agents; Piracetam; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Scopolamine | 1997 |
[Quantitative method for the determination of contents of gastrodin in zhennaonin capsules].
Topics: Benzyl Alcohols; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucosides; Tablets | 1996 |
Isolation and identification of succinic semialdehyde dehydrogenase inhibitory compound from the rhizome of Gastrodia elata Blume.
Topics: Aldehyde Oxidoreductases; Animals; Anticonvulsants; Benzyl Alcohols; Cattle; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glucosides; Plants, Medicinal; Succinate-Semialdehyde Dehydrogenase | 1999 |
[The effect of Tianma injection on cultured vascular smooth muscle cells proliferation].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Benzyl Alcohols; Cell Division; Cells, Cultured; Drugs, Chinese Herbal; Glucosides; Muscle, Smooth, Vascular; Rabbits | 1997 |
[Analysis gastrodin in various types of Gastrodia elata Bl].
Topics: Benzyl Alcohols; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drugs, Chinese Herbal; Glucosides; Magnoliopsida; Plants, Medicinal | 1998 |
Gastrodin decreases immunoreactivities of gamma-aminobutyric acid shunt enzymes in the hippocampus of seizure-sensitive gerbils.
Topics: Animals; Benzyl Alcohols; gamma-Aminobutyric Acid; Gerbillinae; Glucosides; Glutamate Decarboxylase; Hippocampus; Immunochemistry; Isoenzymes; Seizures | 2003 |
[Effect of various nutrient solutions on quality of Gastrodia elata].
Topics: Amino Acids; Benzyl Alcohols; Fertilizers; Gastrodia; Glucosides; Plants, Medicinal; Solutions; Trace Elements | 1998 |
[Studies on chemical constituents from Tibetan medicine wangla(rhizome of Coeloglossum viride var. bracteatum)].
Topics: Benzyl Alcohols; Glucosides; Orchidaceae; Plants, Medicinal; Rhizome; Sitosterols; Tibet | 2002 |
Preparative isolation and purification of gastrodin from the Chinese medicinal plant Gastrodia elata by high-speed counter-current chromatography.
Topics: Benzyl Alcohols; Countercurrent Distribution; Gastrodia; Glucosides; Plants, Medicinal | 2004 |
[Protective effects of gastrodin on the cellular model of Alzheimer's disease induced by Abeta25-35].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Benzyl Alcohols; Cells, Cultured; Cerebral Cortex; Glucosides; Hippocampus; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2005 |
Simultaneous determination of Gastrodin and Ligustrazine hydrochloride in dog plasma by gradient high-performance liquid chromatography.
Topics: Administration, Oral; Animals; Area Under Curve; Benzyl Alcohols; Chromatography, High Pressure Liquid; Dogs; Female; Glucosides; Half-Life; Male; Platelet Aggregation Inhibitors; Pyrazines; Reproducibility of Results | 2006 |
Gastrodin interaction with human fibrinogen: anticoagulant effects and binding studies.
Topics: Animals; Anticoagulants; Benzyl Alcohols; Biosensing Techniques; Fibrinogen; Gastrodia; Glucosides; Humans; Protein Binding; Rats | 2006 |
[Cloning of distinguishing DNA sequences of Gastrodia elata Blume and application of them in identifying gastrodia tuber].
Topics: Base Sequence; Benzyl Alcohols; Cloning, Molecular; Computational Biology; DNA, Plant; Gastrodia; Glucosides; Plant Tubers | 2006 |
[Production of gastrodin through biotransformation of p-hydroxybenzaldehyde by cell suspension cultures of Datura tatula L].
Topics: Benzaldehydes; Benzyl Alcohols; Bioreactors; Biotransformation; Datura; Glucosides; Salicylic Acid; Suspensions | 2006 |
A study of the neuroprotective effect of the phenolic glucoside gastrodin during cerebral ischemia in vivo and in vitro.
Topics: Animals; Benzyl Alcohols; Brain Ischemia; Cell Hypoxia; Chromatography, High Pressure Liquid; Gastrodia; Glucosides; Glutamic Acid; Hippocampus; Male; Neuroprotective Agents; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhizome | 2006 |
[The production of gastrodin through biotransformation of p-hydroxybenzaldehyde by cell suspension culture of Datura stramonium].
Topics: Benzaldehydes; Benzyl Alcohols; Biotransformation; Cell Culture Techniques; Cells, Cultured; Datura stramonium; Glucosides; Plant Stems; Plants, Medicinal | 2006 |
[Preparation and stability investigation of gastrodin dispersible tablets].
Topics: Area Under Curve; Benzyl Alcohols; Chemistry, Pharmaceutical; Drug Stability; Drugs, Chinese Herbal; Glucosides; Lactose; Pharmaceutic Aids; Plants, Medicinal; Solubility; Tablets; Technology, Pharmaceutical | 2006 |
[Synthesis of gastrodin by microbial transformation].
Topics: Benzaldehydes; Benzyl Alcohols; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Glucosides; Models, Biological; Molecular Structure; Rhizopus | 2006 |
Effects of gastrodin on amino acids after cerebral ischemia-reperfusion injury in rat striatum.
Topics: Amino Acids; Animals; Benzyl Alcohols; Chromatography, High Pressure Liquid; Corpus Striatum; Glucosides; Infarction, Middle Cerebral Artery; Male; Microdialysis; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2007 |
A microdialysis study of effects of gastrodin on neurochemical changes in the ischemic/reperfused rat cerebral hippocampus.
Topics: Animals; Benzyl Alcohols; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Extracellular Space; gamma-Aminobutyric Acid; Glucosides; Glutamic Acid; Hippocampus; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Ischemic Attack, Transient; Male; Microdialysis; Neurons; Neuroprotective Agents; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors | 2007 |
Analysis of brain distribution and biliary excretion of a nutrient supplement, gastrodin, in rat.
Topics: Animals; Benzyl Alcohols; Bile; Brain; Calibration; Chromatography, High Pressure Liquid; Glucosides; Male; Microdialysis; Rats; Rats, Sprague-Dawley | 2007 |
Pharmacokinetics of Gastrodin in rat plasma and CSF after i.n. and i.v.
Topics: Administration, Intranasal; Animals; Area Under Curve; Benzyl Alcohols; Biological Availability; Blood-Brain Barrier; Central Nervous System Agents; Chromatography, High Pressure Liquid; Glucosides; Injections, Intravenous; Male; Olfactory Mucosa; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2007 |
A hybrid microdevice with a thin PDMS membrane on the detection window for UV absorbance detection.
Topics: Absorption; Benzyl Alcohols; Dimethylpolysiloxanes; Electrophoresis, Microchip; Glucosides; Membranes; Microfluidic Analytical Techniques; Quartz; Spectrophotometry, Ultraviolet | 2007 |
Protective effects of gastrodin on hypoxia-induced toxicity in primary cultures of rat cortical neurons.
Topics: Animals; Benzyl Alcohols; Brain Ischemia; Cell Hypoxia; Cerebral Cortex; Chromatography, High Pressure Liquid; Gastrodia; Glucosides; Glutamic Acid; Neuroprotective Agents; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhizome | 2007 |
Determination of gastrodin and vanillyl alcohol in Gastrodia elata Blume by pressurized liquid extraction at room temperature.
Topics: Benzyl Alcohols; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Ethanol; Gastrodia; Glucosides; Mass Spectrometry; Medicine, Chinese Traditional; Molecular Structure; Plant Extracts; Plants, Medicinal; Reference Standards; Temperature | 2007 |
[Evaluation of the quality of Gastrodia elata Bl. by HPLC-DAD/MS].
Topics: Benzyl Alcohols; Chromatography, High Pressure Liquid; Gastrodia; Glucosides; Mass Spectrometry; Plants, Medicinal; Quality Control; Rhizome | 2007 |
Distribution and metabolism of gastrodin in rat brain.
Topics: Animals; Benzyl Alcohols; Brain; Chromatography, High Pressure Liquid; Glucosides; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrophotometry, Ultraviolet | 2008 |
Evaluation of the extraction efficiency of thermally labile bioactive compounds in Gastrodia elata Blume by pressurized hot water extraction and microwave-assisted extraction.
Topics: Benzyl Alcohols; Chemical Fractionation; Chromatography, High Pressure Liquid; Gastrodia; Glucosides; Microwaves; Plant Extracts; Plants, Medicinal; Reproducibility of Results; Temperature; Water | 2008 |
Effect of borneol on the distribution of gastrodin to the brain in mice via oral administration.
Topics: Administration, Oral; Animals; Benzyl Alcohols; Biological Availability; Brain; Camphanes; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Delivery Systems; Drug Interactions; Glucosides; Intestinal Absorption; Male; Medicine, Chinese Traditional; Mice; Tissue Distribution | 2008 |
Determination and pharmacokinetics of gastrodin and p-hydroxybenzylalcohol after oral administration of Gastrodia elata Bl. extract in rats by high-performance liquid chromatography-electrospray ionization mass spectrometric method.
Topics: Administration, Oral; Animals; Benzyl Alcohols; Calibration; Chromatography, High Pressure Liquid; Gastrodia; Glucosides; Plant Extracts; Rats; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2008 |
[Chemical constituents from the tuber of Cremastra appendiculata].
Topics: Benzyl Alcohols; Glucosides; Hydroxybenzoates; Molecular Structure; Orchidaceae; Plant Tubers; Plants, Medicinal; Succinic Acid | 2008 |
[Brain targeting of gastrodin nasal in situ gel].
Topics: Administration, Intranasal; Animals; Area Under Curve; Benzyl Alcohols; Brain; Cerebellum; Cerebrum; Drug Delivery Systems; Female; Gels; Glucosides; Injections, Intravenous; Male; Olfactory Bulb; Random Allocation; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2008 |
[Study on drug release of gastrodin ion-activated nasal in situ gel in vitro].
Topics: Adhesiveness; Benzyl Alcohols; Calibration; Diffusion; Gels; Glucosides; Kinetics; Models, Chemical; Nasal Mucosa; Solubility | 2008 |
[Expression of NR1 mRNA of NMDA receptor by gastrodine on hypoxia injury in cultured rat cerebral cortical neurons].
Topics: Animals; Benzyl Alcohols; Cells, Cultured; Cerebral Cortex; Female; Gene Expression Regulation; Glucosides; Hypoxia; Neurons; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
Pharmacokinetics of gastrodin and its metabolite p-hydroxybenzyl alcohol in rat blood, brain and bile by microdialysis coupled to LC-MS/MS.
Topics: Animals; Benzyl Alcohols; Bile; Brain; Calibration; Chromatography, Liquid; Glucosides; Male; Microdialysis; Molecular Structure; Plant Roots; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors | 2008 |
Relationships among genetic makeup, active ingredient content, and place of origin of the medicinal plant Gastrodia tuber.
Topics: Benzyl Alcohols; Chromatography, High Pressure Liquid; DNA, Plant; Gastrodia; Glucosides; Phylogeny; Plant Tubers; Plants, Medicinal | 2009 |
Protective effects of gastrodin on lead-induced synaptic plasticity deficits in rat hippocampus.
Topics: Animals; Benzyl Alcohols; Excitatory Postsynaptic Potentials; Female; Glucosides; Hippocampus; Male; Neuronal Plasticity; Rats; Rats, Wistar; Synapses | 2009 |
[Gastrodine represses expression of IL-1 beta, IL-6 induced by hyperglycemia in gitter cells].
Topics: Animals; Benzyl Alcohols; Cells, Cultured; Down-Regulation; Gene Expression; Glucose; Glucosides; Interleukin-1beta; Interleukin-6; Mice; Microglia | 2009 |
[The determination of three effective constituents in wild and cultivated Gastrodia elata from Bomi].
Topics: Amino Acids; Benzyl Alcohols; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fertilizers; Flavonoids; Gastrodia; Glucosides; Plants, Medicinal; Spectrophotometry, Ultraviolet | 2009 |
[Study on the preparation of sustained-release pellets containing active components from Gastrodia elata by fluid-bed coating].
Topics: Acrylic Resins; Benzyl Alcohols; Delayed-Action Preparations; Drug Carriers; Drugs, Chinese Herbal; Gastrodia; Glucosides; Microspheres; Plants, Medicinal; Polymers; Solubility; Technology, Pharmaceutical | 2009 |
Effects of gastrodin on the dopamine system of Tourette's syndrome rat models.
Topics: Animals; Apomorphine; Benzyl Alcohols; Dopamine; Glucosides; Homovanillic Acid; Injections, Intraperitoneal; Male; Medicine, Chinese Traditional; Rats; Tourette Syndrome | 2009 |
[The effect of gastrodine on hepatitic cell line L02 injury induced by ethanol].
Topics: Benzyl Alcohols; Cell Line; Cell Proliferation; Ethanol; Glucosides; Humans; Liver; Membrane Potential, Mitochondrial; Reactive Oxygen Species | 2010 |
Determination and pharmacokinetics of gastrodin in human plasma by HPLC coupled with photodiode array detector.
Topics: Benzyl Alcohols; Chromatography, High Pressure Liquid; Glucosides; Humans | 2010 |
Enzymic synthesis of gastrodin through microbial transformation and purification of gastrodin biosynthesis enzyme.
Topics: Benzaldehydes; Benzyl Alcohols; Biotransformation; Gastrodia; Glucosides; Glucosyltransferases; Hydrogen-Ion Concentration; Molecular Structure; Plant Extracts; Rhizopus; Temperature | 2010 |
The transport of gastrodin in Caco-2 cells and uptake in Bcap37 and Bcap37/MDR1 cells.
Topics: Acridines; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzyl Alcohols; Biological Transport; Blood-Brain Barrier; Breast Neoplasms; Caco-2 Cells; Cell Line, Tumor; Drug Resistance, Multiple; Gastrodia; Glucosides; Humans; Plants, Medicinal; Prohibitins; Rhodamine 123; Tetrahydroisoquinolines; Verapamil | 2010 |
[Pharmacokinetics of gastrodin from compound Tianma granule in rats].
Topics: Animals; Benzyl Alcohols; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drugs, Chinese Herbal; Female; Gastrodia; Glucosides; Male; Ophiopogon; Plants, Medicinal; Rats; Rats, Wistar; Schisandra | 2010 |
Pharmacokinetics comparative study of a novel Chinese traditional herbal formula and its compatibility.
Topics: Administration, Oral; Animals; Benzyl Alcohols; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Interactions; Drugs, Chinese Herbal; Female; Glucosides; Ligusticum; Models, Biological; Rats; Rats, Wistar; Reproducibility of Results; Spectrophotometry, Ultraviolet | 2011 |
Gastrodin inhibits expression of inducible NO synthase, cyclooxygenase-2 and proinflammatory cytokines in cultured LPS-stimulated microglia via MAPK pathways.
Topics: Animals; Benzyl Alcohols; Cell Line; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Cytokines; Glucosides; I-kappa B Proteins; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Microglia; Mitogen-Activated Protein Kinases; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Phosphorylation; Protein Biosynthesis; RNA, Messenger; Transcription Factor RelA; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2011 |
Gastrodin protects against cardiac hypertrophy and fibrosis.
Topics: Animals; Benzyl Alcohols; Cardiomegaly; Collagen; Fibrosis; GATA4 Transcription Factor; Glucosides; Male; MAP Kinase Signaling System; Mice | 2012 |
[UPLC-MS analysis of constituents of dachuanxiong fang active parts absorbed into blood].
Topics: Animals; Benzofurans; Benzyl Alcohols; Chromatography, High Pressure Liquid; Coumaric Acids; Drugs, Chinese Herbal; Glucosides; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley | 2011 |
Formulation and evaluation of in situ gelling systems for intranasal administration of gastrodin.
Topics: Absorption; Acetic Acid; Adhesiveness; Administration, Intranasal; Animals; Anura; Benzyl Alcohols; Chemistry, Pharmaceutical; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Stability; Drugs, Chinese Herbal; Elasticity; Gels; Glucosides; Male; Nasal Mucosa; Pain; Parabens; Permeability; Polysaccharides, Bacterial; Preservatives, Pharmaceutical; Rats; Rats, Sprague-Dawley; Rheology; Sleep; Technology, Pharmaceutical; Temperature; Time Factors; Viscosity; Water | 2011 |
[The pharmacological mechanism of gastrodin on calcitonin gene-related peptide of cultured rat trigeminal ganglion].
Topics: Animals; Benzyl Alcohols; Butadienes; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Flavonoids; Flunarizine; Gastrodia; Glucosides; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Organ Culture Techniques; Plants, Medicinal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sumatriptan; Trigeminal Ganglion; Vasoconstrictor Agents; Vasodilator Agents | 2011 |
Gastrodin inhibits allodynia and hyperalgesia in painful diabetic neuropathy rats by decreasing excitability of nociceptive primary sensory neurons.
Topics: Animals; Benzyl Alcohols; Capsaicin; Diabetic Neuropathies; Glucosides; Hyperalgesia; Rats; Sensory Receptor Cells; Streptozocin | 2012 |
Gastrodin improved baroreflex sensitivity and increased gamma-amino butyric acid content in brains without decreasing blood pressure in spontaneously hypertensive rats.
Topics: Animals; Baroreflex; Benzyl Alcohols; Blood Pressure; Brain; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glucosides; Glutamic Acid; Mass Spectrometry; Rats; Rats, Inbred SHR | 2012 |
Gastrodin inhibits cell proliferation in vascular smooth muscle cells and attenuates neointima formation in vivo.
Topics: Animals; Becaplermin; Benzyl Alcohols; Cell Cycle; Cell Proliferation; Cells, Cultured; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Glucosides; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Muscle Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley | 2012 |
Gastrodin protect primary cultured rat hippocampal neurons against amyloid-beta peptide-induced neurotoxicity via ERK1/2-Nrf2 pathway.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Benzyl Alcohols; Cells, Cultured; Dose-Response Relationship, Drug; Drug Administration Schedule; Embryo, Mammalian; Enzyme Inhibitors; Female; Flavonoids; Glucosides; Hippocampus; MAP Kinase Signaling System; Neurons; NF-E2-Related Factor 2; Peptide Fragments; Pregnancy; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Up-Regulation | 2012 |
[Effect and mechanism of gastrodin in relaxing isolated thoracic aorta rings in rats].
Topics: Animals; Aorta, Thoracic; Benzyl Alcohols; Calcium; Endothelium, Vascular; Glucosides; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Vasodilation | 2012 |
Simultaneous determination of gastrodin and puerarin in rat plasma by HPLC and the application to their interaction on pharmacokinetics.
Topics: Animals; Benzyl Alcohols; Biological Availability; Chromatography, High Pressure Liquid; Drug Interactions; Drugs, Chinese Herbal; Gastrodia; Glucosides; Isoflavones; Male; Pueraria; Random Allocation; Rats; Rats, Wistar; Reproducibility of Results | 2013 |
Gastrodin attenuation of the inflammatory response in H9c2 cardiomyocytes involves inhibition of NF-κB and MAPKs activation via the phosphatidylinositol 3-kinase signaling.
Topics: Androstadienes; Animals; Anti-Inflammatory Agents; Benzyl Alcohols; Cell Survival; Cells, Cultured; Enzyme Activation; Glucosides; Interleukin-6; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; NF-kappa B; Nitric Oxide Synthase Type II; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Signal Transduction; Tumor Necrosis Factor-alpha; Wortmannin | 2013 |
Role of glucose transporters in the intestinal absorption of gastrodin, a highly water-soluble drug with good oral bioavailability.
Topics: Animals; Benzyl Alcohols; Biological Availability; Caco-2 Cells; Cell Line, Tumor; Diabetes Mellitus, Experimental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Humans; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 1; Solubility | 2013 |
Gastrodin production from p-2-hydroxybenzyl alcohol through biotransformation by cultured cells of Aspergillus foetidus and Penicillium cyclopium.
Topics: Aspergillus; Benzyl Alcohols; Biotransformation; Culture Media; Gastrodia; Glucose; Glucosides; Magnetic Resonance Spectroscopy; Oleic Acid; Penicillium; Polysorbates; Spectrometry, Mass, Electrospray Ionization | 2013 |
Synthesis and anti-influenza virus activities of a novel class of gastrodin derivatives.
Topics: Animals; Antiviral Agents; Benzyl Alcohols; Female; Glucosides; Hemagglutination; Influenza A Virus, H1N1 Subtype; Inhibitory Concentration 50; Mice; Neuraminidase; Oseltamivir; Structure-Activity Relationship; Viral Matrix Proteins | 2013 |
Gastrodia elata Blume and its pure compounds protect BV-2 microglial-derived cell lines against β-amyloid: the involvement of GRP78 and CHOP.
Topics: Amyloid; Animals; Benzyl Alcohols; Cell Death; Cell Survival; Endoplasmic Reticulum Chaperone BiP; Gastrodia; Glucosides; Mice; Microglia | 2012 |
Gastrodin stimulates anticancer immune response and represses transplanted H22 hepatic ascitic tumor cell growth: Involvement of NF-κB signaling activation in CD4+ T cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzyl Alcohols; CD4-Positive T-Lymphocytes; Dose-Response Relationship, Drug; Flow Cytometry; Glucosides; Immunity, Cellular; Liver Neoplasms, Experimental; Male; Mice; Neoplasm Transplantation; NF-kappa B; Real-Time Polymerase Chain Reaction; Signal Transduction | 2013 |
The characteristics of open-tubular capillary electrochromatography columns with series/mixed stationary phases constructed with magnetic nanoparticle coating.
Topics: Benzaldehydes; Benzyl Alcohols; Capillary Electrochromatography; Citric Acid; Gastrodia; Glucosides; Magnetite Nanoparticles; Microscopy, Electron, Scanning; Organosilicon Compounds; Plant Extracts; Polyamines; Rhizome; Silicon Dioxide | 2013 |
[Research the extraction and detection method of gastrodin content in Gastrodia elata].
Topics: Benzyl Alcohols; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Gastrodia; Glucosides; Liquid-Liquid Extraction; Plant Roots; Plants, Medicinal; Solvents; Technology, Pharmaceutical; Temperature; Time Factors; Water | 2012 |
[Chemical constituents from Pleione bulbocodioides].
Topics: Benzaldehydes; Benzyl Alcohols; Biflavonoids; Glucosides; Hydroquinones; Magnetic Resonance Spectroscopy; Molecular Structure; Orchidaceae; Phenols; Rhizome; Stilbenes | 2012 |
Gastrodin ameliorates Parkinson's disease by downregulating connexin 43.
Topics: Animals; Astrocytes; Benzyl Alcohols; Cell Communication; Connexin 43; Disease Models, Animal; Down-Regulation; Gap Junctions; Gene Expression Regulation; Glucosides; Parkinson Disease; Phosphorylation; Rats; Rotenone | 2013 |
[Eighty-seven cases of vertigo treated by acupuncture and acupoint injection of gastrodin].
Topics: Acupuncture Points; Acupuncture Therapy; Adult; Aged; Aged, 80 and over; Benzyl Alcohols; Female; Glucosides; Humans; Male; Middle Aged; Vertigo | 2013 |
Gastrodin ameliorates anxiety-like behaviors and inhibits IL-1beta level and p38 MAPK phosphorylation of hippocampus in the rat model of posttraumatic stress disorder.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzyl Alcohols; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Hippocampus; Interleukin-1beta; Interleukin-6; Male; Motor Activity; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Stress Disorders, Post-Traumatic; Time Factors | 2013 |
Gastrodin ameliorates depressive-like behaviors and up-regulates the expression of BDNF in the hippocampus and hippocampal-derived astrocyte of rats.
Topics: Animals; Antidepressive Agents; Astrocytes; Behavior, Animal; Benzyl Alcohols; Brain-Derived Neurotrophic Factor; Depressive Disorder; Glial Fibrillary Acidic Protein; Glucosides; Helplessness, Learned; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Stress, Psychological; Up-Regulation | 2014 |
Gastrodin ameliorates depression-like behaviors and up-regulates proliferation of hippocampal-derived neural stem cells in rats: involvement of its anti-inflammatory action.
Topics: Animals; Antidepressive Agents; Benzyl Alcohols; Cell Survival; Cells, Cultured; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Food Preferences; Glucosides; Hippocampus; Male; Maze Learning; Neural Stem Cells; Rats; Stress, Psychological; Sucrose; Swimming; Up-Regulation | 2014 |
Gastrodin inhibits glutamate-induced apoptosis of PC12 cells via inhibition of CaMKII/ASK-1/p38 MAPK/p53 signaling cascade.
Topics: Animals; Apoptosis; Benzyl Alcohols; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Survival; Cytochromes c; Glucosides; Glutamic Acid; MAP Kinase Kinase Kinase 5; Membrane Potential, Mitochondrial; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Rats; Signal Transduction; Tumor Suppressor Protein p53 | 2014 |
Gastrodin inhibits the activity of acid-sensing ion channels in rat primary sensory neurons.
Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Animals; Benzyl Alcohols; Cell Membrane; Dose-Response Relationship, Drug; Electrophysiological Phenomena; Formaldehyde; Ganglia, Spinal; Glucosides; Male; Nociception; Protons; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells | 2014 |
Gastrodin alleviates memory deficits and reduces neuropathology in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Benzyl Alcohols; Brain; Cytokines; Disease Models, Animal; Glucosides; Maze Learning; Memory Disorders; Mice; Mice, Transgenic; Microglia; Neuroprotective Agents; RNA, Messenger | 2014 |
Molecularly imprinted polymers with novel functional monomer for selective solid-phase extraction of gastrodin from the aqueous extract of Gastrodia elata.
Topics: Allyl Compounds; Benzyl Alcohols; Gastrodia; Glucosides; Hydrogen Bonding; Molecular Imprinting; Plant Extracts; Plant Roots; Polymerization; Polymers; Solid Phase Extraction; Solvents; Styrenes; Water | 2014 |
Gastrodin ameliorates memory deficits in 3,3'-iminodipropionitrile-induced rats: possible involvement of dopaminergic system.
Topics: Animals; Benzyl Alcohols; Dopamine; Glucosides; Hippocampus; Male; Memory Disorders; Nitriles; Rats; Rats, Wistar; Receptors, Dopamine D2 | 2014 |
Gastrodin protects against MPP(+)-induced oxidative stress by up regulates heme oxygenase-1 expression through p38 MAPK/Nrf2 pathway in human dopaminergic cells.
Topics: 1-Methyl-4-phenylpyridinium; Base Sequence; Benzyl Alcohols; Cell Line, Tumor; DNA Primers; Dopamine; Gastrodia; Glucosides; Heme Oxygenase-1; Humans; NF-E2-Related Factor 2; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2014 |
[Chemical constituents from whole plants of Aconitum tanguticum (III)].
Topics: Aconitum; Benzyl Alcohols; Furaldehyde; Glucosides; Molecular Structure; Phenols; Plant Extracts; Spectrometry, Mass, Electrospray Ionization | 2014 |
Identification and analysis of gastrodin and its five metabolites using ultra fast liquid chromatography electrospray ionization tandem mass spectrometry to investigate influence of multiple-dose and food.
Topics: Animals; Benzaldehydes; Benzyl Alcohols; Central Nervous System Agents; Chromatography, High Pressure Liquid; Female; Glucosides; Hydroxybenzoates; Limit of Detection; Male; Rats; Rats, Sprague-Dawley; Reference Standards; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
[Exploring the best dried processing condition of fresh Gastrodia elata].
Topics: Analysis of Variance; Benzyl Alcohols; Chromatography, High Pressure Liquid; Desiccation; Drug Storage; Gastrodia; Glucosides; Hot Temperature; Plant Tubers; Quality Control; Technology, Pharmaceutical; Time Factors | 2014 |
Analysis and pharmacokinetics studies of gastrodin and p-hydroxybenzyl alcohol in dogs using ultra fast liquid chromatography-tandem mass spectrometry method.
Topics: Administration, Oral; Animals; Benzyl Alcohols; Calibration; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Drug Stability; Glucosides; Limit of Detection; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
Gastrodin prevents motor deficits and oxidative stress in the MPTP mouse model of Parkinson's disease: involvement of ERK1/2-Nrf2 signaling pathway.
Topics: Analysis of Variance; Animals; Ataxia; Benzyl Alcohols; Blotting, Western; DNA Primers; Glucosides; Glutathione; Heme Oxygenase-1; Malondialdehyde; MAP Kinase Signaling System; Mesencephalon; Mice; Molecular Structure; NF-E2-Related Factor 2; Oxidative Stress; Parkinsonian Disorders; Real-Time Polymerase Chain Reaction; Rotarod Performance Test; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2014 |
Relative bioavailability of gastrodin and parishin from extract and powder of Gastrodiae rhizoma in rat.
Topics: Administration, Oral; Animals; Benzyl Alcohols; Biological Availability; Calibration; Chromatography, High Pressure Liquid; Citrates; Drug Stability; Gastrodia; Glucosides; Male; Phytotherapy; Plant Extracts; Plants, Medicinal; Powders; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Rhizome; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
[Screening of 10 types of Chinese herbal compounds inhibiting Abeta and their possible related mechanism in vitro].
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Apoptosis; Benzyl Alcohols; Cell Line; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Glucosides; Humans; Monoterpenes; Phenanthrenes; Saponins | 2014 |
Dual regulating effects of gastrodin on extracellular dopamine concentration in rats models of Tourette's syndrome.
Topics: Animals; Apomorphine; Benzyl Alcohols; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Down-Regulation; Glucosides; Haloperidol; Homovanillic Acid; Male; Nitriles; Rats; Stereotyped Behavior; Tourette Syndrome; Up-Regulation | 2015 |
Highly efficient and enzymatic regioselective undecylenoylation of gastrodin in 2-methyltetrahydrofuran-containing systems.
Topics: Acylation; Benzyl Alcohols; Burkholderia cepacia; Enzyme Stability; Furans; Glucosides; Kinetics; Lipase; Solvents; Stereoisomerism; Substrate Specificity; Undecylenic Acids | 2014 |
Gastrodin prevents steroid-induced osteonecrosis of the femoral head in rats by anti-apoptosis.
Topics: Animals; Apoptosis; Benzyl Alcohols; Femur Head Necrosis; Glucosides; Lipopolysaccharides; Male; Rats; Rats, Wistar; Steroids | 2014 |
[Pharmacokinetics of gastrodin from Tiangou Jiangya capsule in rats].
Topics: Administration, Oral; Animals; Benzyl Alcohols; Blood Pressure; Female; Flavonoids; Furans; Gastrodia; Glucosides; Lignans; Male; Rats; Rats, Sprague-Dawley; Software | 2014 |
Gastrodin suppresses the amyloid β-induced increase of spontaneous discharge in the entorhinal cortex of rats.
Topics: Action Potentials; Amyloid beta-Peptides; Animals; Benzyl Alcohols; Entorhinal Cortex; Glucosides; Male; Neurons; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2014 |
[Characteristics and drug analysis associated with vertigo disease in real world].
Topics: Adolescent; Adult; Aged; Benzyl Alcohols; Betahistine; Diagnosis, Differential; Female; Glucosides; Humans; Male; Medicine, Chinese Traditional; Middle Aged; Vertigo; Young Adult | 2014 |
Dual restoring effects of gastrodin on dopamine in rat models of Tourette's syndrome.
Topics: Animals; Benzyl Alcohols; Corpus Striatum; Dopamine; Glucosides; Male; Rats, Wistar; Receptors, Dopamine D2; Stereotyped Behavior; Tourette Syndrome | 2015 |
Gastrodin: an ancient Chinese herbal medicine as a source for anti-osteoporosis agents via reducing reactive oxygen species.
Topics: Animals; Benzyl Alcohols; Cell Differentiation; Cell Line; Drugs, Chinese Herbal; Female; Glucosides; Humans; Interleukin-6; Mice; Mice, Inbred BALB C; Osteoporosis; Ovariectomy; RANK Ligand; Reactive Oxygen Species | 2015 |
Gastrodin alleviates cerebral ischemic damage in mice by improving anti-oxidant and anti-inflammation activities and inhibiting apoptosis pathway.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Benzyl Alcohols; Brain Ischemia; Cytokines; Glucosides; Inflammation Mediators; Mice; Mice, Inbred C57BL; Oxidative Stress | 2015 |
[Simultaneous determination of gastrodin and eight nucleosides and nucleobases in Tibet cultured gastrodia elata by HPLC method].
Topics: Benzyl Alcohols; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Gastrodia; Glucosides; Nucleosides; Nucleotides | 2014 |
Ameliorative effect of gastrodin on 3,3'-iminodipropionitrile-induced memory impairment in rats.
Topics: Animals; Avoidance Learning; Benzyl Alcohols; Cognition; Environmental Pollutants; Glucosides; Hippocampus; Male; Memory Disorders; Nitriles; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Plasma Membrane Transport Proteins | 2015 |
Vasorelaxation effect of gastrodin on isolated thoracic aorta rings of rats.
Topics: Animals; Aorta, Thoracic; Benzyl Alcohols; Calcium; Endothelium, Vascular; Female; Glucosides; In Vitro Techniques; Male; Phenylephrine; Rats; Rats, Wistar; Vasodilation | 2015 |
Analysis of the metabolic profile of parishin by ultra-performance liquid chromatography/quadrupole-time of flight mass spectrometry.
Topics: Animals; Benzyl Alcohols; Chromatography, High Pressure Liquid; Citrates; Glucosides; Glucuronides; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Sulfates | 2015 |
Anticonvulsive and neuroprotective effects of synergetic combination of phenytoin and gastrodin on the convulsion induced by penicillin in mice.
Topics: Animals; Anticonvulsants; Benzyl Alcohols; Dose-Response Relationship, Drug; Drug Synergism; Glucosides; Hippocampus; Male; Memory; Memory Disorders; Mice; Neurons; Neuroprotective Agents; Penicillins; Phenytoin; Postural Balance; Psychomotor Performance; Seizures; Survival Rate; Transcription Factor RelA | 2015 |
[Pharmacokinetic study on combined application of gastrodin and puerarin in rats].
Topics: Administration, Oral; Animals; Benzyl Alcohols; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucosides; Isoflavones; Male; Rats; Rats, Wistar | 2015 |
[Analysis on 315 cases of clinical adverse drug reaction/event induced by gastrodin].
Topics: Adolescent; Adult; Aged; Benzyl Alcohols; Child; Child, Preschool; China; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Female; Gastrointestinal Tract; Glucosides; Humans; Male; Middle Aged; Retrospective Studies; Skin; Young Adult | 2015 |
[Chemical Constituents from Cremastra appendiculata].
Topics: Benzyl Alcohols; Cinnamates; Glucosides; Orchidaceae; Phenols; Phytochemicals; Plant Tubers; Plants, Medicinal; Propionates | 2015 |
Pharmacokinetic study of Gastrodia elata in rats.
Topics: Administration, Intravenous; Animals; Area Under Curve; Benzyl Alcohols; Citrates; Female; Gastrodia; Glucosides; Male; Plant Extracts; Rats; Rats, Sprague-Dawley | 2015 |
Comparative pharmacokinetics of gastrodin in rats after intragastric administration of free gastrodin, parishin and Gastrodia elata extract.
Topics: Animals; Benzyl Alcohols; Chromatography, High Pressure Liquid; Citrates; Gastrodia; Glucosides; Infusions, Parenteral; Plant Extracts; Rats, Sprague-Dawley; Rhizome | 2015 |
Protective effect of gastrodin on bile duct ligation-induced hepatic fibrosis in rats.
Topics: Animals; Benzyl Alcohols; Bile; Blood Chemical Analysis; Cholestasis; Glucosides; Ligation; Liver; Liver Cirrhosis; Rats; Urinalysis | 2015 |
Report of cold agglutinins in a patient with acute ischemic stroke.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Basal Ganglia; Benzyl Alcohols; Brain; Brain Ischemia; Cerebral Infarction; Cryoglobulins; Diffusion Magnetic Resonance Imaging; Glucosides; Humans; Magnetic Resonance Angiography; Male; Paresis; Risk Factors; Stroke; Temperature; Tomography, X-Ray Computed | 2015 |
Superhydrophilic molecularly imprinted polymers based on a water-soluble functional monomer for the recognition of gastrodin in water media.
Topics: Benzyl Alcohols; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Gastrodia; Glucosides; Limit of Detection; Plant Roots; Polymerization; Polymers; Reproducibility of Results; Solid Phase Extraction; Water | 2015 |
Gastrodin Ameliorates Oxidative Stress and Proinflammatory Response in Nonalcoholic Fatty Liver Disease through the AMPK/Nrf2 Pathway.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Antioxidants; Benzyl Alcohols; Gastrodia; Glucosides; Heme Oxygenase-1; Hep G2 Cells; Humans; Inflammation; Male; Malondialdehyde; Mice, Inbred C57BL; NF-E2-Related Factor 2; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phytotherapy; Plant Extracts; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Triglycerides | 2016 |
Protective Effects of Gastrodin Against Autophagy-Mediated Astrocyte Death.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Astrocytes; Autophagy; Beclin-1; Benzyl Alcohols; Biomarkers; Cell Survival; Cells, Cultured; Down-Regulation; Gastrodia; Glucosides; Humans; Membrane Proteins; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Plant Extracts; Rhizome; Signal Transduction; TOR Serine-Threonine Kinases | 2016 |
Pharmacological characterization of a novel gastrodin derivative as a potential anti-migraine agent.
Topics: Analgesics; Animals; Benzyl Alcohols; Calcitonin Gene-Related Peptide; Female; Glucosides; Male; Mice; Mice, Inbred ICR; Migraine Disorders; Molecular Structure; Nitric Oxide; Nitroglycerin; Pain; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Toxicity Tests; Trigeminal Nuclei | 2016 |
De novo biosynthesis of Gastrodin in Escherichia coli.
Topics: Bacterial Proteins; Benzyl Alcohols; Escherichia coli; Glucosides; Glycosyltransferases; Nocardia; Oxidoreductases; Plant Proteins; Rhodiola | 2016 |
Gastrodin improves cognitive dysfunction and decreases oxidative stress in vascular dementia rats induced by chronic ischemia.
Topics: Alcohol Dehydrogenase; Animals; Antioxidants; Apoptosis; Behavior, Animal; Benzyl Alcohols; Brain; Brain Ischemia; Cell Line, Tumor; Cerebrovascular Circulation; Chronic Disease; Cognition; Dementia, Vascular; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Glutathione Peroxidase; Humans; Male; Malondialdehyde; Maze Learning; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Sulfhydryl Compounds; Time Factors | 2015 |
Gastrodin Attenuates Cognitive Deficits Induced by 3,3'-Iminodipropionitrile.
Topics: Animals; Benzyl Alcohols; Cognition Disorders; gamma-Aminobutyric Acid; Gastrodia; Glucosides; Hippocampus; Male; Maze Learning; Nitriles; Random Allocation; Rats; Rats, Wistar | 2016 |
[Effects of Electroacupuncture Intervention Combined with Gastrodin on Expression of Proteins Related to Proliferation-differentiation of Neural Stem Cells in Hippocampal CA 1 and CA 3 Regions in Focal Cerebral Ischemia Rats].
Topics: Animals; Benzyl Alcohols; Brain Ischemia; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cell Differentiation; Cell Proliferation; Combined Modality Therapy; Disease Models, Animal; Drugs, Chinese Herbal; Electroacupuncture; Glial Fibrillary Acidic Protein; Glucosides; Humans; Male; Nestin; Neural Stem Cells; Rats; Rats, Sprague-Dawley | 2015 |
Anti-depressant effects of Gastrodia elata Blume and its compounds gastrodin and 4-hydroxybenzyl alcohol, via the monoaminergic system and neuronal cytoskeletal remodeling.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Behavior, Animal; Benzyl Alcohols; Brain; Cell Line, Tumor; Cytoskeleton; Dopamine; Exploratory Behavior; Gastrodia; Glucosides; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Neurons; Plant Extracts; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin | 2016 |
Comparative transcriptome analysis of Gastrodia elata (Orchidaceae) in response to fungus symbiosis to identify gastrodin biosynthesis-related genes.
Topics: Agaricales; Benzyl Alcohols; Gastrodia; Gene Expression Regulation, Plant; Gene Ontology; Glucosides; High-Throughput Nucleotide Sequencing; Molecular Sequence Annotation; Mycorrhizae; Plant Tubers; RNA, Plant; Sequence Analysis, RNA; Symbiosis; Transcriptome | 2016 |
Gastrodin suppresses BACE1 expression under oxidative stress condition via inhibition of the PKR/eIF2α pathway in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Benzyl Alcohols; Cell Line, Tumor; Disease Models, Animal; eIF-2 Kinase; Glucosides; Hippocampus; Humans; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Signal Transduction; Spatial Memory | 2016 |
Antidepressant-like effects of water extract of Gastrodia elata Blume in rats exposed to unpredictable chronic mild stress via modulation of monoamine regulatory pathways.
Topics: Animals; Antidepressive Agents; Benzyl Alcohols; Brain; Corticosterone; Depression; Dopamine; Gastrodia; Glucosides; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; PC12 Cells; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhizome; Serotonin; Solvents; Stress, Psychological; Tyrosine 3-Monooxygenase; Water | 2016 |
Gastrodin Protects Neural Progenitor Cells Against Amyloid β (1-42)-Induced Neurotoxicity and Improves Hippocampal Neurogenesis in Amyloid β (1-42)-Injected Mice.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Benzyl Alcohols; Cell Line, Tumor; Cells, Cultured; Cytokines; Doublecortin Domain Proteins; Doublecortin Protein; Glucosides; Hippocampus; Humans; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinases; Neural Stem Cells; Neurogenesis; Neuropeptides; Neuroprotective Agents; Nitric Oxide; Peptide Fragments; SOXB1 Transcription Factors | 2016 |
[Effect of Electroacupuncture Intervention Combined with Gastrodin Administration on Neurological Function, Nogo-A and NgR Expression in the Frontal Lobe Cortex of Focal Cerebral Ischemia Rats].
Topics: Animals; Benzyl Alcohols; Brain Ischemia; Combined Modality Therapy; Electroacupuncture; Frontal Lobe; Gene Expression; Glucosides; GPI-Linked Proteins; Humans; Male; Myelin Proteins; Nogo Proteins; Nogo Receptor 1; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface | 2016 |
Specific targeted quantification combined with non-targeted metabolite profiling for quality evaluation of Gastrodia elata tubers from different geographical origins and cultivars.
Topics: Benzyl Alcohols; China; Chromatography, High Pressure Liquid; Discriminant Analysis; Drugs, Chinese Herbal; Gastrodia; Geographic Mapping; Glucosides; Least-Squares Analysis; Mass Spectrometry; Metabolome; Metabolomics; Plant Roots; Plants, Medicinal; Principal Component Analysis; Support Vector Machine | 2016 |
The Role of Gastrodin on Hippocampal Neurons after N-Methyl-D-Aspartate Excitotoxicity and Experimental Temporal Lobe Seizures.
Topics: Animals; Anticonvulsants; Benzyl Alcohols; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Dentate Gyrus; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Glucosides; Hippocampus; Injections, Intraventricular; Kindling, Neurologic; N-Methylaspartate; Neurons; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Seizures | 2016 |
Pharmacokinetic comparative study of gastrodin after oral administration of Gastrodia elata Bl. extract and its compatibility with the different indigents of Ligusticum chuanxiong Hort. to rats.
Topics: Administration, Oral; Alkaloids; Animals; Area Under Curve; Benzyl Alcohols; Chromatography, High Pressure Liquid; Coumaric Acids; Drug Interactions; Female; Gastrodia; Glucosides; Half-Life; Hydroxybenzoates; Ligusticum; Metabolic Clearance Rate; Phytotherapy; Plant Extracts; Plants, Medicinal; Pyrazines; Rats, Wistar | 2016 |
Global profiling and rapid matching of natural products using diagnostic product ion network and in silico analogue database: Gastrodia elata as a case study.
Topics: Benzyl Alcohols; Biological Products; Chromatography, High Pressure Liquid; Computer Simulation; Data Mining; Databases, Factual; Drug Discovery; Gastrodia; Glucosides; Mass Spectrometry; Nucleosides; Phospholipids; Plant Extracts; Structure-Activity Relationship | 2016 |
Gastrodin reversed the traumatic stress-induced depressed-like symptoms in rats.
Topics: Animals; Antidepressive Agents; Benzyl Alcohols; Brain-Derived Neurotrophic Factor; Depression; Depressive Disorder; Disease Models, Animal; Gastrodia; Glucosides; Hippocampus; Locus Coeruleus; Male; Neuropeptide Y; Norepinephrine; Phytotherapy; Plant Extracts; Rats, Sprague-Dawley; Stress Disorders, Post-Traumatic; Swimming; Tyrosine 3-Monooxygenase | 2016 |
Gastrodin ameliorates spinal cord injury via antioxidant and anti-inflammatory effects.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Benzyl Alcohols; Blood-Brain Barrier; Drug Evaluation, Preclinical; Glucosides; Male; Neuroprotective Agents; Oxidative Stress; Permeability; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries | 2016 |
Gastrodin Pretreatment Impact on Sarcoplasmic Reticulum Calcium Transport ATPase (SERCA) and Calcium Phosphate (PLB) Expression in Rats with Myocardial Ischemia Reperfusion.
Topics: Animals; Benzyl Alcohols; Calcium; Calcium Phosphates; Calcium-Binding Proteins; Coronary Artery Disease; Glucosides; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2016 |
Proliferation-enhancing effects of gastrodin on RSC96 Schwann cells by regulating ERK1/2 and PI3K signaling pathways.
Topics: Animals; Benzyl Alcohols; Cell Proliferation; Glucosides; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Rats; Schwann Cells; Signal Transduction | 2016 |
Gastrodin Reduces the Severity of Status Epilepticus in the Rat Pilocarpine Model of Temporal Lobe Epilepsy by Inhibiting Nav1.6 Sodium Currents.
Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Temporal Lobe; Glucosides; Male; NAV1.6 Voltage-Gated Sodium Channel; Pilocarpine; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Sodium Channel Blockers; Status Epilepticus | 2017 |
Gastrodin ameliorates subacute phase cerebral ischemia‑reperfusion injury by inhibiting inflammation and apoptosis in rats.
Topics: Animals; Apoptosis; Benzyl Alcohols; Brain Ischemia; Caspase 3; Cyclooxygenase 2; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Regulation; Glucosides; Humans; Inflammation; Interleukin-1beta; Nitric Oxide Synthase Type II; Rats; Reperfusion Injury | 2016 |
Gastrodin relieved complete Freund's adjuvant-induced spontaneous pain by inhibiting inflammatory response.
Topics: Analgesics; Animals; Anti-Anxiety Agents; Anti-Inflammatory Agents; Anxiety; Astrocytes; Benzyl Alcohols; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Freund's Adjuvant; Glial Fibrillary Acidic Protein; Glucosides; Gyrus Cinguli; Hot Temperature; Hyperalgesia; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Pain; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Touch; Tumor Necrosis Factor-alpha | 2016 |
[Effect and mechanism of traditional Chinese herbs against Aβ expression in brain tissues of mice with Alzheimer's disease].
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Benzyl Alcohols; Brain; Disease Models, Animal; Glucosides; Hippocampus; Memory; Mice; Mice, Transgenic; Monoterpenes; Plaque, Amyloid; Random Allocation; Saponins; Triterpenes | 2016 |
Gastrodin protects against chronic inflammatory pain by inhibiting spinal synaptic potentiation.
Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Analgesia; Animals; Benzyl Alcohols; Chronic Pain; Glucosides; Inflammation; Mice; Spine; Synaptic Potentials | 2016 |
Gastrodin Attenuates Pentylenetetrazole-Induced Seizures by Modulating the Mitogen-Activated Protein Kinase-Associated Inflammatory Responses in Mice.
Topics: Animals; Anti-Inflammatory Agents; Benzyl Alcohols; Convulsants; CREB-Binding Protein; Disease Models, Animal; Glucosides; Inflammation; Interleukin-10; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; Pentylenetetrazole; Seizures; Tumor Necrosis Factor-alpha | 2017 |
Relative tissue distribution and excretion studies of gastrodin and parishin from powder and extract of Gastrodiae Rhizoma in rat by UHPLC-ESI-MS/MS.
Topics: Animals; Benzyl Alcohols; Biological Availability; Chromatography, High Pressure Liquid; Gastrodia; Glucosides; Limit of Detection; Male; Plant Extracts; Powders; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tissue Distribution | 2017 |
Gastrodin inhibits osteoclastogenesis via down-regulating the NFATc1 signaling pathway and stimulates osseointegration in vitro.
Topics: Animals; Benzyl Alcohols; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Glucosides; Mice; Mice, Inbred C57BL; Osseointegration; Osteoclasts; Osteogenesis; Signal Transduction | 2017 |
BCL6 mediates the effects of Gastrodin on promoting M2-like macrophage polarization and protecting against oxidative stress-induced apoptosis and cell death in macrophages.
Topics: Animals; Antioxidants; Apoptosis; Arginase; Benzyl Alcohols; Biomarkers; Case-Control Studies; Caspase 3; Cell Differentiation; Cell Line; Cerebral Palsy; Child, Preschool; Female; Gene Expression Regulation; Glucosides; Humans; Hydrogen Peroxide; Infant; Lectins, C-Type; Macrophages; Male; Membrane Glycoproteins; Mice; Proto-Oncogene Proteins c-bcl-6; Psychomotor Performance; Receptors, Cell Surface; Receptors, Immunologic; RNA, Small Interfering; Signal Transduction | 2017 |
Gastrodin protects against LPS-induced acute lung injury by activating Nrf2 signaling pathway.
Topics: Acute Lung Injury; Animals; Benzyl Alcohols; Biomarkers; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Glucosides; Heme Oxygenase-1; Inflammation Mediators; Lipopolysaccharides; Mice; NF-E2-Related Factor 2; NF-kappa B; Peroxidase; Protective Agents; Respiratory Function Tests; Signal Transduction | 2017 |
Cytotoxic effects of gastrodin extracted from the rhizome of Gastrodia elata Blume in glioblastoma cells, but not in normal astrocytes, via the induction of oxidative stress-associated apoptosis that involved cell cycle arrest and p53 activation.
Topics: Animals; Apoptosis; Astrocytes; Benzyl Alcohols; Cell Cycle Checkpoints; Cell Line, Tumor; Gastrodia; Glioblastoma; Glucosides; Humans; Mitochondria; Oxidative Stress; Plant Extracts; Rats; Reactive Oxygen Species; Rhizome; Tumor Suppressor Protein p53 | 2017 |
Comparative effects of traditional Chinese and Western migraine medicines in an animal model of nociceptive trigeminovascular activation.
Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Dura Mater; Glucosides; Levetiracetam; Male; Medicine, Chinese Traditional; Migraine Disorders; Neurons, Afferent; Nociceptive Pain; Pain Management; Propranolol; Pyrazines; Rats, Sprague-Dawley; Trigeminal Nerve | 2018 |
[Effect of combination of gastrodia and uncaria on pharmacokinetics of gastrodin and rhynchophylline].
Topics: Animals; Benzyl Alcohols; Gastrodia; Glucosides; Indole Alkaloids; Medicine, Chinese Traditional; Oxindoles; Uncaria | 2017 |
Gastrodin causes vasodilation by activating K
Topics: Animals; Benzyl Alcohols; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Drugs, Chinese Herbal; Gastrodia; Glucosides; Humans; Intracellular Signaling Peptides and Proteins; Isoquinolines; KATP Channels; Mesenteric Arteries; Muscle, Smooth, Vascular; Organ Culture Techniques; Patch-Clamp Techniques; Phenylephrine; Rats; Signal Transduction; Sulfonamides; Vasodilation | 2017 |
Simultaneous determination of ferulic acid and gastrodin of Tianshu Capsule in rat plasma by ultra-fast liquid chromatography with tandem mass spectrometry and its application to a comparative pharmacokinetic study in normal and migraine rats.
Topics: Animals; Benzyl Alcohols; Chromatography, High Pressure Liquid; Coumaric Acids; Drugs, Chinese Herbal; Glucosides; Migraine Disorders; Rats; Reproducibility of Results; Tandem Mass Spectrometry | 2017 |
The Content Analysis of Gastrodin and Gastrodigenin Obtained by Different Processing Methods.
Topics: Benzyl Alcohols; Chromatography, High Pressure Liquid; Gastrodia; Glucosides; Plant Extracts | 2018 |
Gastrodin reduces IL-1β-induced apoptosis, inflammation, and matrix catabolism in osteoarthritis chondrocytes and attenuates rat cartilage degeneration in vivo.
Topics: Animals; Apoptosis; Benzyl Alcohols; Bone Matrix; Cartilage, Articular; Chondrocytes; Dose-Response Relationship, Drug; Gastrodia; Glucosides; Inflammation; Interleukin-1beta; Male; Metabolism; Osteoarthritis; Rats; Rats, Sprague-Dawley | 2018 |
Enhanced Agronomic Traits and Medicinal Constituents of Autotetraploids in Anoectochilus formosanus Hayata, a Top-Grade Medicinal Orchid.
Topics: Benzyl Alcohols; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Glucosides; Orchidaceae; Plant Leaves; Plant Roots; Plant Stems; Quantitative Trait Loci; Tandem Mass Spectrometry; Tetraploidy | 2017 |
An Optimized and Sensitive Pharmacokinetic Quantitative Method of Investigating Gastrodin, Parishin, and Parishin B, C and E in Beagle Dog Plasma using LC-MS/MS after Intragastric Administration of Tall Gastrodia Capsules.
Topics: Animals; Benzyl Alcohols; Capsules; Chromatography, High Pressure Liquid; Citrates; Dogs; Drug Administration Routes; Gastrodia; Glucosides; Male; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Time Factors | 2017 |
Gastrodin protects myocardial cells against hypoxia/reoxygenation injury in neonatal rats by inhibiting cell autophagy through the activation of mTOR signals in PI3K-Akt pathway.
Topics: Animals; Animals, Newborn; Autophagosomes; Autophagy; Autophagy-Related Protein-1 Homolog; Benzyl Alcohols; Cell Proliferation; Cell Survival; Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; Female; Glucosides; Male; Microtubule-Associated Proteins; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Sequestosome-1 Protein; Signal Transduction; TOR Serine-Threonine Kinases | 2018 |
New Alkaloid and Aromatic Glucoside from the Flowers of Cymbidium Lunagrad Eternal Green.
Topics: Alkaloids; Arbutin; Benzyl Alcohols; Flavonoids; Flowers; Glucosides; Magnetic Resonance Spectroscopy; Molecular Structure; Orchidaceae; Plant Extracts | 2018 |
Evaluation of the Mitochondria-Related Redox and Bioenergetics Effects of Gastrodin in SH-SY5Y Cells Exposed to Hydrogen Peroxide.
Topics: Adenosine Triphosphate; Antioxidants; Benzyl Alcohols; Cell Line, Tumor; Glucosides; Humans; Hydrogen Peroxide; Mitochondria; NF-E2-Related Factor 2; Oxidation-Reduction | 2018 |
Novel Strategies Using Total Gastrodin and Gastrodigenin, or Total Gastrodigenin for Quality Control of Gastrodia elata.
Topics: Benzyl Alcohols; Drugs, Chinese Herbal; Gastrodia; Glucosides; Plants, Medicinal; Quality Control | 2018 |
Gastrodin protects MC3T3-E1 osteoblasts from dexamethasone-induced cellular dysfunction and promotes bone formation via induction of the NRF2 signaling pathway.
Topics: Animals; Benzyl Alcohols; Cell Line; Dexamethasone; Drugs, Chinese Herbal; Female; Gastrodia; Glucocorticoids; Glucosides; Mice; NF-E2-Related Factor 2; Osteoblasts; Osteogenesis; Osteoporosis; Protective Agents; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Gastrodin Suppresses Pentylenetetrazole-Induced Seizures Progression by Modulating Oxidative Stress in Zebrafish.
Topics: Animals; Benzyl Alcohols; Convulsants; Disease Progression; Dose-Response Relationship, Drug; Glucosides; Oxidative Stress; Pentylenetetrazole; Reactive Oxygen Species; Seizures; Zebrafish | 2018 |
[Electroacupuncture plus Gastrodin Improves Learning-memory Ability Possibly by Up-regulating Expression of SIRT 1 and PGC-1 ɑ in Hippocampal CA 1 Region of Alzheimer's Disease Rats].
Topics: Alzheimer Disease; Animals; Benzyl Alcohols; Electroacupuncture; Glucosides; Hippocampus; Male; Memory; Rats; Rats, Sprague-Dawley | 2018 |
Gastrodin microinjection suppresses 6-OHDA-induced motor impairments in parkinsonian rats: insights into oxidative balance and microglial activation in SNc.
Topics: Animals; Benzyl Alcohols; Catalepsy; Glucosides; Lipid Peroxidation; Male; Microglia; Microinjections; Nitric Oxide; Oxidation-Reduction; Oxidopamine; Parkinsonian Disorders; Pars Compacta; Peroxidase; Rats; Rats, Wistar | 2018 |
Gastrodin inhibits high glucose‑induced human retinal endothelial cell apoptosis by regulating the SIRT1/TLR4/NF‑κBp65 signaling pathway.
Topics: Apoptosis; Benzyl Alcohols; Cell Survival; Endothelial Cells; Glucose; Glucosides; Humans; Oxidative Stress; Reactive Oxygen Species; Retina; Signal Transduction; Sirtuin 1; Toll-Like Receptor 4; Transcription Factor RelA | 2018 |
Four new phenolic constituents from the rhizomes of Gastrodia elata Blume.
Topics: Animals; Benzyl Alcohols; Cell Death; Cell Line; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Gastrodia; Glucosides; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Neurons; Neuroprotective Agents; Oxidopamine; Phenols; Plant Extracts; Rhizome | 2019 |
Gastrodin Protects against Ethanol-Induced Liver Injury and Apoptosis in HepG2 Cells and Animal Models of Alcoholic Liver Disease.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Benzyl Alcohols; Cell Survival; Disease Models, Animal; Ethanol; Glucosides; Hep G2 Cells; Humans; Liver; Liver Diseases, Alcoholic; Male; Membrane Potential, Mitochondrial; Mice, Inbred ICR; Protective Agents; Rats, Sprague-Dawley | 2018 |
[Effect and mechanism of gastrodin inhibiting β-amyloid plaques in brain of mice].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzyl Alcohols; Brain; Disease Models, Animal; Glucosides; Memory; Memory Disorders; Mice; Mice, Transgenic; Plaque, Amyloid | 2016 |
[Structure-activity relationship of gastrodin and parishins on learning and memory deficits induced by scopolamine].
Topics: Animals; Benzyl Alcohols; Citrates; Gastrodia; Glucosides; Memory Disorders; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats; Rhizome; Scopolamine; Spatial Learning; Structure-Activity Relationship | 2016 |
Gastrodin pretreatment alleviates myocardial ischemia/reperfusion injury through promoting autophagic flux.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Apoptosis; Autophagy; Benzyl Alcohols; Cardiotonic Agents; Cells, Cultured; Gastrodia; Glucosides; Male; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phosphorylation; Protein Kinases; Rats; TOR Serine-Threonine Kinases | 2018 |
Inhibition of the Nrf2/HO-1 Axis Suppresses the Mitochondria-Related Protection Promoted by Gastrodin in Human Neuroblastoma Cells Exposed to Paraquat.
Topics: Benzyl Alcohols; Cell Line, Tumor; Cytoprotection; Glucosides; Heme Oxygenase-1; Herbicides; Humans; Membrane Potential, Mitochondrial; Mitochondria; Neuroblastoma; NF-E2-Related Factor 2; Paraquat; Reactive Oxygen Species | 2019 |
Gastrodin attenuates microglia activation through renin-angiotensin system and Sirtuin3 pathway.
Topics: Animals; Benzyl Alcohols; Glucosides; Inflammation Mediators; Lipopolysaccharides; Microglia; NADPH Oxidases; Neurodegenerative Diseases; Rats, Sprague-Dawley; Renin-Angiotensin System; Sirtuin 3 | 2018 |
[Antibacterial Activity of Chemical Constituents Isolated from Fibrous Roots of Bletilla striata].
Topics: Anti-Bacterial Agents; Benzyl Alcohols; Drugs, Chinese Herbal; Glucosides; Orchidaceae; Phenanthrenes; Plant Roots; Staphylococcus aureus | 2016 |
Gastrodin Protects Cardiomyocytes from Anoxia/Reoxygenation Injury by 14-3-3
Topics: 14-3-3 Proteins; Animals; Benzyl Alcohols; Gastrodia; Glucosides; Hypoxia; Myocytes, Cardiac | 2018 |
Gastrodin induced HO-1 and Nrf2 up-regulation to alleviate H2O2-induced oxidative stress in mouse liver sinusoidal endothelial cells through p38 MAPK phosphorylation.
Topics: Animals; Apoptosis; Benzyl Alcohols; Cell Survival; Endothelial Cells; Glucosides; Heme Oxygenase-1; Hydrogen Peroxide; Liver; Malondialdehyde; Mice; Models, Theoretical; NF-E2-Related Factor 2; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Up-Regulation | 2018 |
Hepatoprotective effect of gastrodin against alcohol-induced liver injury in mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Benzyl Alcohols; Catalase; Chemical and Drug Induced Liver Injury; Chemokine CXCL1; Cytochrome P-450 CYP2E1; Ethanol; Female; Gene Expression Regulation; Glucosides; Glutathione Peroxidase; Humans; Interferon-gamma; Interleukin-6; Liver; Mice; NF-E2-Related Factor 2; NF-kappa B; Signal Transduction; STAT3 Transcription Factor; Superoxide Dismutase; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2019 |
[Role of mitochondrial permeability transition pore in mediating the inhibitory effect of gastrodin on oxidative stress in cardiac myocytes
Topics: Adenosine Triphosphate; Apoptosis; Benzyl Alcohols; Caspase 3; Cell Line; Cell Survival; Cyclosporine; Cytochromes c; Glucosides; Humans; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocytes, Cardiac; Oxidative Stress; Reactive Oxygen Species | 2018 |
Gastrodin Alleviates Cognitive Dysfunction and Depressive-Like Behaviors by Inhibiting ER Stress and NLRP3 Inflammasome Activation in db/db Mice.
Topics: Animals; Apoptosis; Behavior, Animal; Benzyl Alcohols; Blood Glucose; Body Weight; Cognitive Dysfunction; Depression; Dyslipidemias; Endoplasmic Reticulum Stress; Glucosides; Inflammasomes; Insulin Resistance; Male; Memory; Mice; Models, Biological; Neurons; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein | 2018 |
Protective effect of gastrodin on peripheral neuropathy induced by anti-tumor treatment with vincristine in rat models.
Topics: Analgesics; Animals; Antineoplastic Agents, Phytogenic; Benzyl Alcohols; Breast Neoplasms; Chemokine CX3CL1; CX3C Chemokine Receptor 1; Female; Glucosides; Interleukin-1beta; Microglia; Neuralgia; p38 Mitogen-Activated Protein Kinases; Pain Threshold; Peripheral Nervous System Diseases; Rats, Sprague-Dawley; Signal Transduction; Spine; Tumor Necrosis Factor-alpha; Vincristine | 2021 |
Effect of Gastrodin on Early Brain Injury and Neurological Outcome After Subarachnoid Hemorrhage in Rats.
Topics: Animals; Apoptosis; Astrocytes; Benzyl Alcohols; Blood-Brain Barrier; Brain; Brain Edema; Calcium; Glucosides; Glutamic Acid; Male; Microglia; Neurons; Neuroprotective Agents; Oxidative Stress; Rats, Sprague-Dawley; Subarachnoid Hemorrhage | 2019 |
Gastrodin protects rat cardiomyocytes H9c2 from hypoxia-induced injury by up-regulation of microRNA-21.
Topics: Animals; Benzyl Alcohols; Cell Hypoxia; Cell Line; Cell Proliferation; Cell Survival; Cytoprotection; Down-Regulation; Glucosides; MicroRNAs; Myocytes, Cardiac; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Signal Transduction; Up-Regulation | 2019 |
Post-stroke gastrodin treatment ameliorates ischemic injury and increases neurogenesis and restores the Wnt/β-Catenin signaling in focal cerebral ischemia in mice.
Topics: Animals; Apoptosis; Benzyl Alcohols; beta Catenin; Brain; Brain Ischemia; Disease Models, Animal; Doublecortin Protein; Glucosides; Infarction, Middle Cerebral Artery; Ischemia; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neuroprotective Agents; Stroke; Wnt Signaling Pathway | 2019 |
Optimal Extraction Study of Gastrodin-Type Components from
Topics: Antioxidants; Benzyl Alcohols; Chromatography, High Pressure Liquid; Citrates; Gastrodia; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Medicine, Chinese Traditional; Phytochemicals; Plant Extracts; Surface Properties | 2019 |
Gastrodin pretreatment alleviates rat brain injury caused by cerebral ischemic-reperfusion.
Topics: Animals; Benzyl Alcohols; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Brain Ischemia; Capillary Permeability; Glucosides; Infarction, Middle Cerebral Artery; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Microglia; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury | 2019 |
Efficacy of combination therapy in adolescent and adult patients with total-deafness sudden sensorineural hearing loss.
Topics: Adolescent; Age Factors; Anti-Inflammatory Agents; Batroxobin; Benzyl Alcohols; Drug Therapy, Combination; Female; Fibrinolytic Agents; Glucosides; Hearing Loss, Sudden; Humans; Male; Methylprednisolone; Middle Aged | 2019 |
Gastrodin attenuates neuroinflammation in DOI-induce Tourette syndrome in rats.
Topics: Amphetamines; Animals; Behavior, Animal; Benzyl Alcohols; Cytokines; Disease Models, Animal; Glucosides; Inflammation; Male; MAP Kinase Signaling System; Rats; Rats, Sprague-Dawley; Tourette Syndrome | 2019 |
Early intervention with gastrodin reduces striatal neurotoxicity in adult rats with experimentally‑induced diabetes mellitus.
Topics: Animals; Benzyl Alcohols; Biomarkers; Brain-Derived Neurotrophic Factor; Corpus Striatum; Diabetes Mellitus, Experimental; Gene Expression; Glucosides; Glutamic Acid; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Neurons; Rats; Receptor, trkB | 2019 |
Effect of the SSeCKS-TRAF6 interaction on gastrodin-mediated protection against 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced astrocyte activation and neuronal death.
Topics: Animals; Astrocytes; Benzyl Alcohols; Cell Death; Female; Glucosides; Mice; Neurons; NF-kappa B; Polychlorinated Dibenzodioxins; Transfection | 2019 |
Quality Evaluation of
Topics: Benzyl Alcohols; Chromatography, High Pressure Liquid; Citrates; Gastrodia; Glucosides; Plant Extracts; Plant Tubers; Quality Control | 2019 |
Lipid Modulating Anti-oxidant Stress Activity of Gastrodin on Nonalcoholic Fatty Liver Disease Larval Zebrafish Model.
Topics: Animals; Antioxidants; Benzyl Alcohols; Disease Models, Animal; Gastrodia; Gene Expression Regulation; Glucosides; Larva; Lipid Metabolism; Non-alcoholic Fatty Liver Disease; Zebrafish | 2019 |
Gastrodin attenuates proliferation and inflammatory responses in activated microglia through Wnt/β-catenin signaling pathway.
Topics: Animals; Benzyl Alcohols; Cell Cycle; Cell Line; Cyclin D1; Glucosides; Glycogen Synthase Kinase 3 beta; Ki-67 Antigen; Macrophage Activation; Macrophages; Microglia; Neuroimmunomodulation; Nitric Oxide Synthase Type II; Primary Cell Culture; Rats; Tumor Necrosis Factor-alpha; Wnt Signaling Pathway | 2019 |
Protective effect of gastrodin against methamphetamine-induced autophagy in human dopaminergic neuroblastoma SH-SY5Y cells via the AKT/mTOR signaling pathway.
Topics: Autophagy; Benzyl Alcohols; Cell Line, Tumor; Central Nervous System Stimulants; Dopaminergic Neurons; Glucosides; Humans; Methamphetamine; Neuroblastoma; Neuroprotective Agents; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases | 2019 |
Nrf2 Mediates the Anti-apoptotic and Anti-inflammatory Effects Induced by Gastrodin in Hydrogen Peroxide-Treated SH-SY5Y Cells.
Topics: Apoptosis; Benzyl Alcohols; Cell Line, Tumor; DNA Fragmentation; Glucosides; Humans; Hydrogen Peroxide; Interleukin-1beta; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; NF-kappa B; Poly(ADP-ribose) Polymerases; Tumor Necrosis Factor-alpha | 2019 |
Gastrodin protects dopaminergic neurons via insulin-like pathway in a Parkinson's disease model.
Topics: alpha-Synuclein; Animals; Animals, Genetically Modified; Benzyl Alcohols; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Chemotaxis; Dopaminergic Neurons; Dose-Response Relationship, Drug; Forkhead Transcription Factors; Glucosides; Neuroprotection; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Receptor, Insulin; Signal Transduction | 2019 |
Gastrodin Inhibits Inflammasome Through the STAT3 Signal Pathways in TNA2 Astrocytes and Reactive Astrocytes in Experimentally Induced Cerebral Ischemia in Rats.
Topics: Animals; Astrocytes; Benzyl Alcohols; Biomarkers; Cell Line, Transformed; Cells, Cultured; Drug Evaluation, Preclinical; Glucose; Glucosides; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Inflammasomes; Male; Nerve Tissue Proteins; Neuroprotective Agents; NF-kappa B; Oxygen; Phytotherapy; Premedication; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor | 2019 |
[Determination of seven indicative ingredients in oral liquids of Chinese medicine by liquid chromatography-electrospray ionization-ion mobility spectrometry].
Topics: Benzyl Alcohols; Chlorogenic Acid; Chromatography, Liquid; Drugs, Chinese Herbal; Flavonoids; Glucosides; Glycyrrhizic Acid; Ion Mobility Spectrometry; Isoflavones; Lactates; Limit of Detection; Mass Spectrometry; Rutin; Spectrometry, Mass, Electrospray Ionization | 2019 |
Gastrodin, a traditional Chinese medicine monomer compound, can be used as adjuvant to enhance the immunogenicity of melanoma vaccines.
Topics: Adjuvants, Immunologic; Animals; B7-1 Antigen; B7-2 Antigen; Benzyl Alcohols; Cancer Vaccines; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Female; Glucosides; Humans; Immunomodulation; Lymphocyte Activation; Medicine, Chinese Traditional; Melanoma; Mice; Mice, Inbred C57BL; Tumor Burden | 2019 |
Gastrodin ameliorates microvascular reperfusion injury-induced pyroptosis by regulating the NLRP3/caspase-1 pathway.
Topics: Animals; Benzyl Alcohols; Caspase 1; Cell Line; Endothelial Cells; Glucosides; Humans; Inflammasomes; Interleukin-1beta; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Myocardium; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis | 2019 |
Gastrodin alleviates Tourette syndrome via Nrf-2/HO-1/HMGB1/NF-кB pathway.
Topics: Animals; Benzyl Alcohols; Corpus Striatum; Cytokines; gamma-Aminobutyric Acid; Glucosides; Glutamic Acid; Heme Oxygenase-1; HMGB1 Protein; Male; Malondialdehyde; NF-E2-Related Factor 2; NF-kappa B; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tourette Syndrome | 2019 |
Pharmacokinetic comparative study of tetramethylpyrazine and ferulic acid and their compatibility with different concentration of gastrodin and gastrodigenin on blood-stasis migraine model by blood-brain microdialysis method.
Topics: Administration, Oral; Animals; Benzyl Alcohols; Blood-Brain Barrier; Cold Temperature; Coumaric Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drugs, Chinese Herbal; Extracellular Fluid; Gastrodia; Glucosides; Humans; Ligusticum; Male; Microdialysis; Migraine Disorders; Permeability; Pyrazines; Rats; Specific Pathogen-Free Organisms; Vasoconstriction | 2020 |
Gastrodin combined with rhynchophylline inhibits cerebral ischaemia-induced inflammasome activation via upregulating miR-21-5p and miR-331-5p.
Topics: Animals; Benzyl Alcohols; Brain Ischemia; Glucosides; Infarction, Middle Cerebral Artery; Inflammasomes; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Neuroprotective Agents; Oxindoles; Transcriptional Activation | 2019 |
Gastrodin protects against glutamate-induced ferroptosis in HT-22 cells through Nrf2/HO-1 signaling pathway.
Topics: Animals; Benzyl Alcohols; Cell Line; Ferroptosis; Gastrodia; Glucosides; Glutamic Acid; Heme Oxygenase-1; L-Lactate Dehydrogenase; Lipid Peroxidation; Membrane Proteins; Mice; Neurons; NF-E2-Related Factor 2; Protective Agents; Reactive Oxygen Species; Signal Transduction; Translocation, Genetic | 2020 |
Gastrodin Attenuates Neuronal Apoptosis and Neurological Deficits after Experimental Intracerebral Hemorrhage.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Behavior, Animal; Benzyl Alcohols; Brain Edema; Cells, Cultured; Cerebral Cortex; Cerebral Hemorrhage; Disease Models, Animal; Glucosides; Male; Motor Activity; Neurons; Neuroprotective Agents; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Gastrodin Alleviates Vascular Dementia in a 2-VO-Vascular Dementia Rat Model by Altering Amyloid and Tau Levels.
Topics: Amyloid beta-Peptides; Animals; Benzyl Alcohols; Brain Ischemia; Carotid Stenosis; Dementia, Vascular; Disease Models, Animal; Glucosides; Hippocampus; Male; Maze Learning; Memory; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; tau Proteins | 2020 |
Characterization of the Inhibitory Effect of Gastrodigenin and Gastrodin on M-type K
Topics: Benzyl Alcohols; Cell Line, Tumor; Glucosides; Hippocampus; Humans; Membrane Potentials; Neurons; Pituitary Gland; Potassium | 2019 |
The Potential Role of PKA/CREB Signaling Pathway Concerned with Gastrodin Administration on Methamphetamine-Induced Conditioned Place Preference Rats and SH-SY5Y Cell Line.
Topics: Animals; Benzyl Alcohols; Cell Line, Tumor; Central Nervous System Stimulants; Conditioning, Psychological; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Glucosides; Humans; Male; Methamphetamine; Prefrontal Cortex; Random Allocation; Rats; Rats, Sprague-Dawley | 2020 |
Gastrodin Inhibits H
Topics: Animals; Antioxidants; Benzyl Alcohols; Cell Death; Cell Line; Ferroptosis; Glucosides; Hydrogen Peroxide; Phospholipid Hydroperoxide Glutathione Peroxidase; Rats; Reactive Oxygen Species | 2020 |
Elastomeric polyurethane porous film functionalized with gastrodin for peripheral nerve regeneration.
Topics: Animals; Benzyl Alcohols; Biocompatible Materials; Elastomers; Glucosides; Nerve Regeneration; Neuroprotective Agents; PC12 Cells; Polyurethanes; Porosity; Rats; Tissue Engineering; Tissue Scaffolds | 2020 |
Gastrodin protects H9c2 cardiomyocytes against oxidative injury by ameliorating imbalanced mitochondrial dynamics and mitochondrial dysfunction.
Topics: Animals; Apoptosis; Benzyl Alcohols; Cardiotonic Agents; Cell Line; Gene Knockdown Techniques; Glucosides; Hydrogen Peroxide; Mitochondria; Mitochondrial Dynamics; Myocytes, Cardiac; NF-E2-Related Factor 2; Oxidative Stress; Rats | 2020 |
[Gastrodin improves hippocampal neurogenesis by NO-cGMP-PKG signaling pathway in cerebral ischemic mice].
Topics: Animals; Benzyl Alcohols; Brain Ischemia; CA1 Region, Hippocampal; Cognition; Glucosides; Mice; Mice, Inbred C57BL; Neurogenesis; Signal Transduction | 2019 |
Effects of gastrodin against carbon tetrachloride induced kidney inflammation and fibrosis in mice associated with the AMPK/Nrf2/HMGB1 pathway.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Benzyl Alcohols; Carbon Tetrachloride; Disease Models, Animal; Fibrosis; Glucosides; HMGB1 Protein; Inflammation; Kidney Diseases; Male; Mice; Mice, Inbred ICR; NF-E2-Related Factor 2; Phytotherapy; Protein Kinases | 2020 |
Early Intervention of Gastrodin Improved Motor Learning in Diabetic Rats Through Ameliorating Vascular Dysfunction.
Topics: Animals; Apoptosis; Behavior, Animal; Benzyl Alcohols; Cerebellar Cortex; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Endothelium, Vascular; Glucosides; Locomotion; Male; Nitric Oxide; Nitric Oxide Synthase; Purkinje Cells; Rats, Sprague-Dawley; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2020 |
The improvement effect of gastrodin on LPS/GalN-induced fulminant hepatitis via inhibiting inflammation and apoptosis and restoring autophagy.
Topics: Acetyl-CoA Carboxylase; Alanine Transaminase; AMP-Activated Protein Kinase Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspartate Aminotransferases; Autophagy; Benzyl Alcohols; Cytokines; Galactosamine; Glucosides; Hep G2 Cells; Humans; Inflammasomes; Inflammation; Lipopolysaccharides; Male; Massive Hepatic Necrosis; Mice, Inbred C57BL; NF-kappa B p50 Subunit; NLR Family, Pyrin Domain-Containing 3 Protein; Protein Kinases; Survival Rate | 2020 |
Effects of Gastrodin against Lead-Induced Brain Injury in Mice Associated with the Wnt/Nrf2 Pathway.
Topics: Animals; Benzyl Alcohols; Brain Injuries; Disease Models, Animal; Glucosides; Hippocampus; Lead; Lead Poisoning; Male; Mice; Mice, Inbred ICR; Neuroprotective Agents; NF-E2-Related Factor 2; Wnt Signaling Pathway | 2020 |
Gastrodin Pretreatment Protects Liver Against Ischemia-Reperfusion Injury via Activation of the Nrf2/HO-1 Pathway.
Topics: Animals; Antioxidants; Benzyl Alcohols; Cytokines; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Glucosides; Heme Oxygenase-1; Liver; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phytotherapy; Preoperative Care; Reperfusion Injury; Signal Transduction; Toll-Like Receptor 4 | 2020 |
Effects of Gastrodin on BV2 cells under oxygen-glucose deprivation and its mechanism.
Topics: Animals; Apoptosis; Benzyl Alcohols; Cell Hypoxia; Cell Line; Glucose; Glucosides; Mice; Microglia; Neuroprotection; Oxygen; Signal Transduction | 2021 |
Pharmacokinetic comparative study of GAS with different concentration of tetramethylpyrazine and ferulic acid on liver-yang hyperactivity migraine model by blood-brain microdialysis method.
Topics: Animals; Benzyl Alcohols; Brain; Coumaric Acids; Glucosides; Liver; Microdialysis; Migraine Disorders; Pyrazines | 2020 |
Gastrodin alleviates bone damage by modulating protein expression and tissue redox state.
Topics: Animals; Apoptosis; Benzyl Alcohols; Bone and Bones; Cancellous Bone; Cell Line; Cell Proliferation; Chronic Disease; Femur; Fluorides; Fluorosis, Dental; Glucosides; Humans; Male; Oxidation-Reduction; Oxidative Stress; Proteins; Rats, Wistar | 2020 |
Gastrodin Regulates the Notch Signaling Pathway and Sirt3 in Activated Microglia in Cerebral Hypoxic-Ischemia Neonatal Rats and in Activated BV-2 Microglia.
Topics: Animals; Animals, Newborn; Benzyl Alcohols; Carotid Artery, Common; Cells, Cultured; Cerebral Cortex; Corpus Callosum; Diamines; Disease Models, Animal; Drug Synergism; Gene Expression Regulation; Glucosides; Hypoxia-Ischemia, Brain; Ligation; Lipopolysaccharides; Microglia; Neuroinflammatory Diseases; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Notch1; Signal Transduction; Sirtuins; Thiazoles; Tumor Necrosis Factor-alpha | 2021 |
Gastrodin promotes CNS myelination via a lncRNA Gm7237/miR-142a/MRF pathway.
Topics: Animals; Benzyl Alcohols; Central Nervous System; Gene Expression Regulation; Glucosides; Mice; Mice, Inbred C57BL; MicroRNAs; Myelin Sheath; RNA, Long Noncoding; Transcription Factors | 2021 |
Gastrodin alleviates perioperative neurocognitive dysfunction of aged mice by suppressing neuroinflammation.
Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Benzyl Alcohols; Cognition; Disease Models, Animal; Fear; Glucosides; Glycogen Synthase Kinase 3 beta; Hippocampus; Inflammation Mediators; Interleukin-10; Interleukin-1beta; Interleukin-6; Male; Maze Learning; Mice, Inbred C57BL; Microglia; Perioperative Period; Phosphorylation; Postoperative Cognitive Complications; tau Proteins; Tumor Necrosis Factor-alpha | 2021 |
Metabolic engineering of Saccharomyces cerevisiae for high-level production of gastrodin from glucose.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Bacterial Proteins; Benzyl Alcohols; Biosynthetic Pathways; Genetic Engineering; Glucose; Glucosides; Glucosyltransferases; Industrial Microbiology; Metabolic Engineering; Oxidoreductases; Oxo-Acid-Lyases; Plant Proteins; Saccharomyces cerevisiae; Transferases (Other Substituted Phosphate Groups) | 2020 |
Gastrodin prevents homocysteine-induced human umbilical vein endothelial cells injury via PI3K/Akt/eNOS and Nrf2/ARE pathway.
Topics: Benzyl Alcohols; Glucosides; Homocysteine; Human Umbilical Vein Endothelial Cells; Humans; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt | 2021 |
Gastrodin alleviates seizure severity and neuronal excitotoxicities in the rat lithium-pilocarpine model of temporal lobe epilepsy via enhancing GABAergic transmission.
Topics: Animals; Anticonvulsants; Benzyl Alcohols; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Gastrodia; Glucosides; Hippocampus; Lithium; Male; Medicine, Chinese Traditional; Neurons; Neuroprotective Agents; Pilocarpine; Rats, Sprague-Dawley; Receptors, GABA-A; Rhizome; Seizures; Status Epilepticus | 2021 |
Gastrodin Promotes the Survival of Random-Pattern Skin Flaps via Autophagy Flux Stimulation.
Topics: Animals; Apoptosis; Autophagy; Benzyl Alcohols; Glucosides; Graft Survival; Male; Necrosis; Neovascularization, Physiologic; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Skin | 2021 |
Gastrodin - A potential drug used for the treatment of Tourette Syndrome.
Topics: Animals; Benzyl Alcohols; Brain; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Gastrodia; Glucosides; Male; Molecular Imaging; Phytotherapy; Positron-Emission Tomography; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tourette Syndrome | 2021 |
[Antioxidant mechanism of gastrodin combined with isorhynchophylline in inhibiting MPP~+-induced apoptosis of PC12 cells].
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antioxidants; Apoptosis; Benzyl Alcohols; Cell Survival; Glucosides; Glycogen Synthase Kinase 3 beta; Oxindoles; PC12 Cells; Rats | 2021 |
Gastrodin attenuates lithium-pilocarpine-induced epilepsy by activating AMPK-mediated PPARα in a juvenile rat model.
Topics: Adenylate Kinase; Animals; Behavior, Animal; Benzyl Alcohols; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Electroencephalography; Enzyme Activation; Epilepsy; Glucosides; Lithium Compounds; Nerve Growth Factor; Pilocarpine; PPAR alpha; Rats; Rats, Sprague-Dawley; Signal Transduction | 2021 |
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca
Topics: Animals; Autophagy; Benzyl Alcohols; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Dementia, Vascular; Glucosides; Hippocampus; Learning; Male; Maze Learning; Memory; Memory Disorders; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction | 2021 |
Clinical therapeutic effects of gastrodin in combination with betahistine on vertigo: A protocol for systematic review and meta-analysis.
Topics: Benzyl Alcohols; Betahistine; China; Drug Therapy, Combination; Glucosides; Humans; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Systematic Reviews as Topic; Treatment Outcome; Vertigo | 2021 |
Gastrodin Alleviates Cerebral Ischaemia/Reperfusion Injury by Inhibiting Pyroptosis by Regulating the lncRNA NEAT1/miR-22-3p Axis.
Topics: Animals; Benzyl Alcohols; Brain; Cell Hypoxia; Glucose; Glucosides; Infarction, Middle Cerebral Artery; Inflammation; Male; MicroRNAs; Neurons; Neuroprotective Agents; Oxygen; Pyroptosis; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Long Noncoding | 2021 |
Comparative study on the intestinal absorption of three gastrodin analogues via the glucose transport pathway.
Topics: Animals; Benzyl Alcohols; Caco-2 Cells; Glucose; Glucosides; Humans; Intestinal Absorption; Intestinal Mucosa; Molecular Docking Simulation; Rats; Sodium-Glucose Transporter 1 | 2021 |
Gastrodin induces lysosomal biogenesis and autophagy to prevent the formation of foam cells via AMPK-FoxO1-TFEB signalling axis.
Topics: AMP-Activated Protein Kinases; Animals; Atherosclerosis; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Benzyl Alcohols; Foam Cells; Forkhead Box Protein O1; Gene Expression Regulation; Glucosides; Lysosomes; Macrophages; Mice | 2021 |
Gastrodin alleviates inflammatory injury of cardiomyocytes in septic shock mice via inhibiting NLRP3 expression.
Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Glucosides; Inflammation; Interleukin-1beta; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; NLR Family, Pyrin Domain-Containing 3 Protein; Shock, Septic | 2021 |
Gastrodin Attenuates Lipopolysaccharide-Induced Inflammatory Response and Migration via the Notch-1 Signaling Pathway in Activated Microglia.
Topics: Animals; Anti-Inflammatory Agents; Benzyl Alcohols; Glucosides; Inflammation; Lipopolysaccharides; Microglia; Rats; Signal Transduction | 2022 |
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Topics: Acetic Acid; Animals; Aorta; Atherosclerosis; Benzyl Alcohols; Butyric Acid; Disease Models, Animal; Drugs, Chinese Herbal; Fatty Acids, Volatile; Gastrodia; Gastrointestinal Microbiome; Glucosides; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1beta; Intestinal Mucosa; Lipids; Mice, Inbred C57BL; Propionates; Tight Junction Proteins; Tumor Necrosis Factor-alpha | 2021 |
Gastrodin extends the lifespan and protects against neurodegeneration in the Drosophila PINK1 model of Parkinson's disease.
Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Drugs, Chinese Herbal; Female; Gastrodia; Glucosides; Humans; Longevity; Male; Neuroprotection; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Protein Serine-Threonine Kinases | 2021 |
Gastrodin Improves Nonalcoholic Fatty Liver Disease Through Activation of the Adenosine Monophosphate-Activated Protein Kinase Signaling Pathway.
Topics: AMP-Activated Protein Kinases; Animals; Benzyl Alcohols; Diet, High-Fat; Disease Models, Animal; Glucosides; Humans; Lipid Metabolism; Male; Mice; Non-alcoholic Fatty Liver Disease; Signal Transduction | 2021 |
Gastrodin promotes hippocampal neurogenesis via PDE9-cGMP-PKG pathway in mice following cerebral ischemia.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Animals, Newborn; Benzyl Alcohols; Brain Ischemia; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Gastrodia; Glucosides; Hippocampus; Male; Maze Learning; Mice; Mice, Inbred C57BL; Neurogenesis; Rats; Rats, Sprague-Dawley; Signal Transduction | 2021 |
The up-regulation of miR-21 by gastrodin to promote the angiogenesis ability of human umbilical vein endothelial cells by activating the signaling pathway of PI3K/Akt.
Topics: Benzyl Alcohols; Cells, Cultured; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; MicroRNAs; Neovascularization, Physiologic; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Up-Regulation | 2021 |
A single low-energy shockwave pulse opens blood-cerebrospinal fluid barriers and facilitates gastrodin delivery to alleviate epilepsy.
Topics: Animals; Benzyl Alcohols; Blood-Brain Barrier; Choroid Plexus; Epilepsy; Glucosides; Rats | 2021 |
Coactivation of GSK3β and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons.
Topics: Amyotrophic Lateral Sclerosis; Animals; Axons; Benzyl Alcohols; Calcium; Cell Differentiation; Glucosides; Glutamic Acid; Glycogen Synthase Kinase 3 beta; Humans; Induced Pluripotent Stem Cells; Insulin-Like Growth Factor I; MAP Kinase Signaling System; Mice, Transgenic; Motor Neurons; Mutation; Nerve Degeneration; Nerve Fibers; Neurites; Superoxide Dismutase-1; Survival Analysis | 2021 |
Gastrodin attenuates perfluorooctanoic acid-induced liver injury by regulating gut microbiota composition in mice.
Topics: Animals; Benzyl Alcohols; Caprylates; Cecum; Cytokines; Disease Models, Animal; Fatty Acids, Volatile; Fluorocarbons; Gastrointestinal Microbiome; Glucosides; Hepatomegaly; Inflammation Mediators; Liver; Male; Mice, Inbred C57BL; Oxidative Stress; Phylogeny; Protective Agents | 2021 |
Gastrodin Pretreatment Alleviates Renal Ischemia-Reperfusion Injury.
Topics: Animals; Antioxidants; Apoptosis; Benzyl Alcohols; Glucosides; Humans; Kidney; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2022 |
Treatment Combining Focused Ultrasound with Gastrodin Alleviates Memory Deficit and Neuropathology in an Alzheimer's Disease-Like Experimental Mouse Model.
Topics: Alzheimer Disease; Animals; Benzyl Alcohols; Blood-Brain Barrier; Brain; Combined Modality Therapy; Disease Models, Animal; Glucosides; Maze Learning; Memory Disorders; Mice; Neuroprotective Agents; Ultrasonography, Interventional | 2022 |
Gastrodin promotes the regeneration of peripheral nerves by regulating miR-497/BDNF axis.
Topics: Animals; Benzyl Alcohols; Brain-Derived Neurotrophic Factor; Glucosides; Hydrogen Peroxide; MicroRNAs; Rats; Schwann Cells | 2022 |
Elucidation of the Transport Mechanism of Puerarin and Gastrodin and Their Interaction on the Absorption in a Caco-2 Cell Monolayer Model.
Topics: Benzyl Alcohols; Biological Transport; Caco-2 Cells; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Glucosides; Humans; Intestinal Absorption; Isoflavones; Kinetics; Molecular Structure; Permeability; Reproducibility of Results | 2022 |
Gastrodin suppresses pyroptosis and exerts neuroprotective effect in traumatic brain injury model by inhibiting NLRP3 inflammasome signaling pathway.
Topics: Animals; Benzyl Alcohols; Brain Injuries, Traumatic; Glucosides; Inflammasomes; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Rats; Signal Transduction | 2022 |
Gastrodin Alleviates Acetaminophen-Induced Liver Injury in a Mouse Model Through Inhibiting MAPK and Enhancing Nrf2 Pathways.
Topics: Acetaminophen; Animals; Antioxidants; Benzyl Alcohols; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Disease Models, Animal; Glucosides; Liver; Mice; NF-E2-Related Factor 2; Oxidative Stress | 2022 |
Gastrodin protects retinal ganglion cells from ischemic injury by activating phosphatidylinositol 3-kinase/protein kinase B/nuclear factor erythroid 2-related factor 2 (PI3K/AKT/Nrf2) signaling pathway.
Topics: Apoptosis; Benzyl Alcohols; Glucose; Glucosides; Humans; Ischemia; NF-E2-Related Factor 2; Oxidative Stress; Oxygen; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Reperfusion Injury; Retinal Ganglion Cells; Signal Transduction | 2022 |
A comparative study of vestibular improvement and gastrointestinal effect of betahistine and gastrodin in mice.
Topics: Animals; Benzyl Alcohols; Betahistine; Glucosides; Mice; Receptors, Histamine H3; Vestibular Nuclei; Vestibule, Labyrinth | 2022 |
Gastrodin ameliorates Concanavalin A-induced acute hepatitis via the IL6/JAK2/STAT3 pathway.
Topics: Animals; Chemical and Drug Induced Liver Injury; Concanavalin A; Cytokines; Glucosides; Hepatitis; Mice; Mice, Inbred C57BL | 2022 |
[Neurobiological effects of gastrodin and its possible use in neurology and psychiatry].
Topics: Amyloid beta-Peptides; Benzyl Alcohols; Glucosides; Humans; Neurology; Psychiatry | 2022 |
Gastrodin Ameliorates Cognitive Dysfunction in Vascular Dementia Rats by Suppressing Ferroptosis via the Regulation of the Nrf2/Keap1-GPx4 Signaling Pathway.
Topics: Animals; Benzyl Alcohols; Cognitive Dysfunction; Cyclooxygenase 2; Dementia, Vascular; Ferroptosis; Glucosides; Glutathione; Kelch-Like ECH-Associated Protein 1; Malondialdehyde; NF-E2-Related Factor 2; Oleanolic Acid; Phospholipid Hydroperoxide Glutathione Peroxidase; Rats; Signal Transduction | 2022 |
Gastrodin relieves cognitive impairment by regulating autophagy via PI3K/AKT signaling pathway in vascular dementia.
Topics: Animals; Autophagy; Cognitive Dysfunction; Dementia, Vascular; Glucosides; Hypoxia; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2023 |