Page last updated: 2024-09-03

gastrodin and 4-hydroxybenzyl alcohol

gastrodin has been researched along with 4-hydroxybenzyl alcohol in 26 studies

Compound Research Comparison

Studies
(gastrodin)
Trials
(gastrodin)
Recent Studies (post-2010)
(gastrodin)
Studies
(4-hydroxybenzyl alcohol)
Trials
(4-hydroxybenzyl alcohol)
Recent Studies (post-2010) (4-hydroxybenzyl alcohol)
3023234101048

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.85)18.7374
1990's5 (19.23)18.2507
2000's7 (26.92)29.6817
2010's9 (34.62)24.3611
2020's4 (15.38)2.80

Authors

AuthorsStudies
Tang, XQ; Tao, YH; Xu, HB; Yang, XL; Yuan, Z1
Guo, Z; Tan, T; Wu, C; Zhong, Y1
Li, L; Zhu, Q1
Chen, YR; Han, GZ; Liu, KX; Su, CY; Tang, NY; Zhang, YL1
He, S; Kuang, A; Tan, T; You, J; Zhong, Y1
Chang, YS; Chen, CF; Hsieh, MT; Huang, SC; Peng, WH; Wu, CR1
Chen, CF; Hsieh, MT; Wu, CR1
Gong, JS; Ma, WP; Pu, JX; Xiao, CJ; Xu, SG; Zheng, SQ1
Sheng, YX; Sun, SQ; Xu, JT; Zhang, JL; Zhang, W1
Cai, Z; Hou, S; Li, Y; Pu, J; Xu, S; Yang, Z; Zhao, B1
Sheng, YX; Zhang, JL; Zhang, W1
Cai, Z; Chen, QH; Hou, SX; Li, YB; Song, XR; Yang, ZX; Zhao, BB1
Chen, YF; Lee, WC; Lin, LC; Tsai, TH; Wu, YT1
Chen, Q; Dong, Y; Fan, L; Xu, T; Zhang, H1
Bhandary, B; Chae, HJ; Chae, SW; Han, SY; Jo, KS; Kim, DS; Kim, HR; Kim, MG; Kim, SY; Lee, BH; Lee, GH; Seo, HN; So, BO1
Jia, Y; Kong, L; Li, X; Liu, Q; Luo, J; Shen, J; Wang, J; Wang, KD; Xie, H2
Chen, WC; Ho, CT; Lai, YS; Lin, SH; Lin, YE; Lu, KH; Panyod, S; Sheen, LY1
Huang, G; Liu, Y1
Tang, C; Wu, B; Wu, J; Yu, B; Zhang, Z1
Ding, A; Fu, Y; Hu, M; Jiang, Y; Shan, M; Wu, Q; Yan, H; Yao, W; Yu, S; Zhang, L1
Cheng, H; Guo, S; Ke, G; Liu, M; Mao, Y; Mi, Y; Wang, M; Wei, P1
Huang, CW; Lai, MC; Liu, PY; Lo, YC; Wu, SN; Yang, CS1
Gao, YG; Gu, PP; He, ZM; Zang, P; Zhang, ZL; Zhao, Y; Zhu, HY1
Cheng, R; Li, YH; Liu, TR; Yuan, Y; Zhao, YY; Zhou, JH1
Cui, C; Kong, M; Liu, Y; Ming, H; Su, Q; Yan, J; Zhang, Z; Zhou, C1

Reviews

1 review(s) available for gastrodin and 4-hydroxybenzyl alcohol

ArticleYear
[Research progress on mechanism of gastrodin and p-hydroxybenzyl alcohol on central nervous system].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2020, Volume: 45, Issue:2

    Topics: Benzyl Alcohols; Central Nervous System; Gastrodia; Glucosides; Humans; Plant Extracts

2020

Other Studies

25 other study(ies) available for gastrodin and 4-hydroxybenzyl alcohol

ArticleYear
Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives.
    Bioorganic & medicinal chemistry letters, 2006, Volume: 16, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Benzaldehydes; Binding Sites; Enzyme Inhibitors; Humans; Structure-Activity Relationship; Succinate-Semialdehyde Dehydrogenase

2006
[Study of the mechanism of gastrodin and derivatives of gastrodigenin].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1991, Volume: 22, Issue:1

    Topics: Animals; Benzyl Alcohols; Butanols; Glucosides; Hypnotics and Sedatives; Rats; Receptors, GABA-A

1991
[A trial of utilizing TDP (specific electromagnetic wave) in cultivating Gastrodia elata Bl].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1990, Volume: 15, Issue:8

    Topics: Benzyl Alcohols; Glucosides; Plants, Medicinal; Radiation

1990
[Determination of gastrodin in biological specimens and in pharmacokinetics].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1987, Volume: 8, Issue:5

    Topics: Animals; Benzyl Alcohols; Biological Availability; Chromatography, High Pressure Liquid; Dogs; Female; Glucosides; Glycosides; Male; Rabbits; Rats; Species Specificity; Tissue Distribution

1987
[Biodistribution and metabolism of 3H-gastrodigenin and 3H-gastrodin in mice].
    Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1994, Volume: 25, Issue:3

    Topics: Animals; Benzyl Alcohols; Enterohepatic Circulation; Female; Glucosides; Mice; Tissue Distribution

1994
Effects of Gastrodia elata and its active constituents on scopolamine-induced amnesia in rats.
    Planta medica, 1996, Volume: 62, Issue:4

    Topics: Amnesia; Animals; Avoidance Learning; Benzyl Alcohols; Drugs, Chinese Herbal; Glucosides; Hypnotics and Sedatives; Male; Memory; Plant Extracts; Rats; Rats, Sprague-Dawley; Scopolamine

1996
Gastrodin and p-hydroxybenzyl alcohol facilitate memory consolidation and retrieval, but not acquisition, on the passive avoidance task in rats.
    Journal of ethnopharmacology, 1997, Volume: 56, Issue:1

    Topics: Animals; Apomorphine; Avoidance Learning; Benzyl Alcohols; Cycloheximide; Dopamine Agonists; Drugs, Chinese Herbal; Electroshock; Glucosides; Hypnotics and Sedatives; Male; Memory; Muscarinic Antagonists; Nootropic Agents; Piracetam; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Scopolamine

1997
[The production of gastrodin through biotransformation of p-hydroxybenzaldehyde by cell suspension culture of Datura stramonium].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:10

    Topics: Benzaldehydes; Benzyl Alcohols; Biotransformation; Cell Culture Techniques; Cells, Cultured; Datura stramonium; Glucosides; Plant Stems; Plants, Medicinal

2006
[Evaluation of the quality of Gastrodia elata Bl. by HPLC-DAD/MS].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2007, Volume: 42, Issue:4

    Topics: Benzyl Alcohols; Chromatography, High Pressure Liquid; Gastrodia; Glucosides; Mass Spectrometry; Plants, Medicinal; Quality Control; Rhizome

2007
Effect of borneol on the distribution of gastrodin to the brain in mice via oral administration.
    Journal of drug targeting, 2008, Volume: 16, Issue:2

    Topics: Administration, Oral; Animals; Benzyl Alcohols; Biological Availability; Brain; Camphanes; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Delivery Systems; Drug Interactions; Glucosides; Intestinal Absorption; Male; Medicine, Chinese Traditional; Mice; Tissue Distribution

2008
Determination and pharmacokinetics of gastrodin and p-hydroxybenzylalcohol after oral administration of Gastrodia elata Bl. extract in rats by high-performance liquid chromatography-electrospray ionization mass spectrometric method.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2008, Volume: 15, Issue:10

    Topics: Administration, Oral; Animals; Benzyl Alcohols; Calibration; Chromatography, High Pressure Liquid; Gastrodia; Glucosides; Plant Extracts; Rats; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2008
[Brain targeting of gastrodin nasal in situ gel].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2008, Volume: 39, Issue:3

    Topics: Administration, Intranasal; Animals; Area Under Curve; Benzyl Alcohols; Brain; Cerebellum; Cerebrum; Drug Delivery Systems; Female; Gels; Glucosides; Injections, Intravenous; Male; Olfactory Bulb; Random Allocation; Rats; Rats, Sprague-Dawley; Tissue Distribution

2008
Pharmacokinetics of gastrodin and its metabolite p-hydroxybenzyl alcohol in rat blood, brain and bile by microdialysis coupled to LC-MS/MS.
    Journal of pharmaceutical and biomedical analysis, 2008, Nov-04, Volume: 48, Issue:3

    Topics: Animals; Benzyl Alcohols; Bile; Brain; Calibration; Chromatography, Liquid; Glucosides; Male; Microdialysis; Molecular Structure; Plant Roots; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors

2008
Gastrodin production from p-2-hydroxybenzyl alcohol through biotransformation by cultured cells of Aspergillus foetidus and Penicillium cyclopium.
    Applied biochemistry and biotechnology, 2013, Volume: 170, Issue:1

    Topics: Aspergillus; Benzyl Alcohols; Biotransformation; Culture Media; Gastrodia; Glucose; Glucosides; Magnetic Resonance Spectroscopy; Oleic Acid; Penicillium; Polysorbates; Spectrometry, Mass, Electrospray Ionization

2013
Gastrodia elata Blume and its pure compounds protect BV-2 microglial-derived cell lines against β-amyloid: the involvement of GRP78 and CHOP.
    Biological research, 2012, Volume: 45, Issue:4

    Topics: Amyloid; Animals; Benzyl Alcohols; Cell Death; Cell Survival; Endoplasmic Reticulum Chaperone BiP; Gastrodia; Glucosides; Mice; Microglia

2012
Identification and analysis of gastrodin and its five metabolites using ultra fast liquid chromatography electrospray ionization tandem mass spectrometry to investigate influence of multiple-dose and food.
    Journal of chromatography. A, 2014, Sep-05, Volume: 1358

    Topics: Animals; Benzaldehydes; Benzyl Alcohols; Central Nervous System Agents; Chromatography, High Pressure Liquid; Female; Glucosides; Hydroxybenzoates; Limit of Detection; Male; Rats; Rats, Sprague-Dawley; Reference Standards; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2014
Analysis and pharmacokinetics studies of gastrodin and p-hydroxybenzyl alcohol in dogs using ultra fast liquid chromatography-tandem mass spectrometry method.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 99

    Topics: Administration, Oral; Animals; Benzyl Alcohols; Calibration; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Drug Stability; Glucosides; Limit of Detection; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2014
Anti-depressant effects of Gastrodia elata Blume and its compounds gastrodin and 4-hydroxybenzyl alcohol, via the monoaminergic system and neuronal cytoskeletal remodeling.
    Journal of ethnopharmacology, 2016, Apr-22, Volume: 182

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Behavior, Animal; Benzyl Alcohols; Brain; Cell Line, Tumor; Cytoskeleton; Dopamine; Exploratory Behavior; Gastrodia; Glucosides; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Neurons; Plant Extracts; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin

2016
The Content Analysis of Gastrodin and Gastrodigenin Obtained by Different Processing Methods.
    Journal of chromatographic science, 2018, Jan-01, Volume: 56, Issue:1

    Topics: Benzyl Alcohols; Chromatography, High Pressure Liquid; Gastrodia; Glucosides; Plant Extracts

2018
Novel Strategies Using Total Gastrodin and Gastrodigenin, or Total Gastrodigenin for Quality Control of Gastrodia elata.
    Molecules (Basel, Switzerland), 2018, Jan-29, Volume: 23, Issue:2

    Topics: Benzyl Alcohols; Drugs, Chinese Herbal; Gastrodia; Glucosides; Plants, Medicinal; Quality Control

2018
Optimal Extraction Study of Gastrodin-Type Components from
    Molecules (Basel, Switzerland), 2019, Feb-02, Volume: 24, Issue:3

    Topics: Antioxidants; Benzyl Alcohols; Chromatography, High Pressure Liquid; Citrates; Gastrodia; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Medicine, Chinese Traditional; Phytochemicals; Plant Extracts; Surface Properties

2019
Pharmacokinetic comparative study of tetramethylpyrazine and ferulic acid and their compatibility with different concentration of gastrodin and gastrodigenin on blood-stasis migraine model by blood-brain microdialysis method.
    Journal of pharmaceutical and biomedical analysis, 2020, Jan-05, Volume: 177

    Topics: Administration, Oral; Animals; Benzyl Alcohols; Blood-Brain Barrier; Cold Temperature; Coumaric Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drugs, Chinese Herbal; Extracellular Fluid; Gastrodia; Glucosides; Humans; Ligusticum; Male; Microdialysis; Migraine Disorders; Permeability; Pyrazines; Rats; Specific Pathogen-Free Organisms; Vasoconstriction

2020
Characterization of the Inhibitory Effect of Gastrodigenin and Gastrodin on M-type K
    International journal of molecular sciences, 2019, Dec-23, Volume: 21, Issue:1

    Topics: Benzyl Alcohols; Cell Line, Tumor; Glucosides; Hippocampus; Humans; Membrane Potentials; Neurons; Pituitary Gland; Potassium

2019
[Screening of an Armillaria gallica strain for Gastrodia elata cultivation].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2023, Volume: 48, Issue:2

    Topics: Armillaria; Gastrodia; Polysaccharides

2023
One-pot biosynthesis of gastrodin using UDP-glycosyltransferase itUGT2 with an in situ UDP-glucose recycling system.
    Enzyme and microbial technology, 2023, Volume: 166

    Topics: Escherichia coli; Glucose; Glycosyltransferases; Uridine Diphosphate Glucose

2023