gastrins and rosaprostol

gastrins has been researched along with rosaprostol* in 1 studies

Other Studies

1 other study(ies) available for gastrins and rosaprostol

Article	Year
The effects of 9-hydroxy-19,20-bis-norprostanoic acid on mucus, acid and gastrin secretion in duodenal ulcer patients. Prostaglandins, leukotrienes, and medicine, 1984, Volume: 15, Issue:2 The effects of 9-hydroxy-19,20-bis norprostanoic acid (rosaprostol, IBI), a new prostaglandin analogue, on gastric secretion and gastrin release were studied in 15 patients with duodenal ulcer. In acute experiments, rosaprostol lowered pentagastrin-stimulated acid secretion by 27-36%, whereas after chronic administration there were no changes in acid secretion or gastrin release (fasting and oxo-stimulated) but N-acetylneuraminic acid (NANA)-glycoproteins increased significantly. Our results indicate that the antisecretory and mucopoietic activities of 9-hydroxy-19,20-bis-norprostanoic acid are the basis of its healing effect in duodenal ulcer patients. Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Duodenal Ulcer; Fatty Acids; Gastric Acid; Gastric Mucosa; Gastrins; Humans; Male; Middle Aged; Prostanoic Acids	1984

Article

Year

The effects of 9-hydroxy-19,20-bis-norprostanoic acid on mucus, acid and gastrin secretion in duodenal ulcer patients.

Prostaglandins, leukotrienes, and medicine, 1984, Volume: 15, Issue:2

The effects of 9-hydroxy-19,20-bis norprostanoic acid (rosaprostol, IBI), a new prostaglandin analogue, on gastric secretion and gastrin release were studied in 15 patients with duodenal ulcer. In acute experiments, rosaprostol lowered pentagastrin-stimulated acid secretion by 27-36%, whereas after chronic administration there were no changes in acid secretion or gastrin release (fasting and oxo-stimulated) but N-acetylneuraminic acid (NANA)-glycoproteins increased significantly. Our results indicate that the antisecretory and mucopoietic activities of 9-hydroxy-19,20-bis-norprostanoic acid are the basis of its healing effect in duodenal ulcer patients.

Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Duodenal Ulcer; Fatty Acids; Gastric Acid; Gastric Mucosa; Gastrins; Humans; Male; Middle Aged; Prostanoic Acids

1984