gastrins and 5-methoxysalicylic-acid

gastrins has been researched along with 5-methoxysalicylic-acid* in 1 studies

Other Studies

1 other study(ies) available for gastrins and 5-methoxysalicylic-acid

Article	Year
Enhanced rectal bioavailability of polypeptides using sodium 5-methoxysalicylate as an absorption promoter. Journal of pharmaceutical sciences, 1982, Volume: 71, Issue:5 The absorption-promoting effect of sodium 5-methoxysalicylate was studied in the rat with respect to rectal delivery of pentagastrin and gastrin. Rectal bioavailability was quantitated by direct comparison of pharmacological effect with intravenous dose response. Coadministration of the absorption adjuvant greatly enhanced the rectal bioavailability of the model polypeptides. Sodium 5-methoxysalicylate, therefore, is representative of a new type of absorption promoter which appears to facilitate rectal absorption of polypeptide drug entities. Topics: Animals; Biological Availability; Gastric Juice; Gastrins; Hydroxybenzoate Ethers; Intestinal Absorption; Male; Pentagastrin; Peptides; Rats; Salicylates; Suppositories	1982

Article

Year

Enhanced rectal bioavailability of polypeptides using sodium 5-methoxysalicylate as an absorption promoter.

Journal of pharmaceutical sciences, 1982, Volume: 71, Issue:5

The absorption-promoting effect of sodium 5-methoxysalicylate was studied in the rat with respect to rectal delivery of pentagastrin and gastrin. Rectal bioavailability was quantitated by direct comparison of pharmacological effect with intravenous dose response. Coadministration of the absorption adjuvant greatly enhanced the rectal bioavailability of the model polypeptides. Sodium 5-methoxysalicylate, therefore, is representative of a new type of absorption promoter which appears to facilitate rectal absorption of polypeptide drug entities.

Topics: Animals; Biological Availability; Gastric Juice; Gastrins; Hydroxybenzoate Ethers; Intestinal Absorption; Male; Pentagastrin; Peptides; Rats; Salicylates; Suppositories

1982