Page last updated: 2024-09-03

garenoxacin and carbostyril

garenoxacin has been researched along with carbostyril in 89 studies

Compound Research Comparison

Studies (garenoxacin)	Trials (garenoxacin)	Recent Studies (post-2010) (garenoxacin)	Studies (carbostyril)	Trials (carbostyril)	Recent Studies (post-2010) (carbostyril)
195	19	46	12,855	1,323	5,611

Research

Studies (89)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	81 (91.01)	29.6817
2010's	8 (8.99)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Aleksunes, L; Bonner, DP; Fung-Tomc, JC; Gradelski, E; Huczko, E; Kolek, B; Minassian, B; Stickle, T; Valera, L; Washo, T	1
Appelbaum, PC; Hoellman, DB; Jacobs, MR; Kelly, LM	1
Jones, RN; Pfaller, MA; Stilwell, M	1
Gales, A; Jones, RN; Sader, H	1
Biedenbach, DJ; Jones, RN; Pfaller, MA	1
Bonner, D; Fung-Tomc, J; Gradelski, E; Kolek, B; Valera, L	1
Barrett, JF; Card, A; Casperson, M; Denbleyker, K; Fan, L; Gouveia, KE; Lawrence, LE; Wu, P	1
Andrews, JM; Wise, R	1
Beach, ML; Biedenbach, DJ; Fix, AM; Jones, RN; Pfaller, MA	1
Bonner, D; Fung-Tomc, J; Kolek, B; Warr, G	1
Andrews, JM; Boswell, FJ; Wise, R	1
Barrett, JF; DenBleyker, K; Dougherty, TJ; Hartman-Neumann, S; Lawrence, LE; Pelosi, LA	1
Boos, M; Fluit, AC; Hafner, D; Jagusch, H; Mayer, S; Schmitz, FJ	1
Ghaffar, F; Hardy, RD; Iglehart, J; McCracken, GH; Michelow, IC; Olsen, K; Rodriguez-Cerrato, V; Saavedra, J	1
Barrett, JF; Denbleyker, KL; Discotto, LF; Lawrence, LE	1
Edelstein, MA; Edelstein, PH; Shinzato, T	1
Bonner, D; Fung-Tomc, J; Gradelski, E; Minassian, B; Valera, L	1
Belian, B; Manzor, O; Pawlak, J; Saravolatz, L	1
Barrett, JF; Denbleyker, KL; Lawrence, LE; Wu, P	1
Biedenbach, DJ; Deshpande, L; Jones, RN	1
Acosta, F; Cottagnoud, M; Cottagnoud, P; Pfister, M; Täuber, MG	1
Barrett, JF; Chaniewski, S; Frosco, M; Hooper, DC; Lawrence, LE; Ryan, B; Yang, H	1
Andriole, VT; Bassetti, M; Callan, DA; Dembry, LM; Farrel, PA	1
Andrews, JM; Gee, T; Marshall, G; Wise, R	1
Appelbaum, PC; Davies, TA; Jacobs, MR; Nagai, K; Pankuch, GA	1
Andrews, JM; Jevons, G; Weller, TM; Wise, R	1
Biedenbach, DJ; Jones, RN	2
Hammerschlag, MR; Kutlin, A; Malay, S; Reznik, T; Roblin, PM	1
Boos, M; Fluit, AC; Jagusch, H; Mayer, S; Schmitz, FJ	1
Nicolau, DP; Nightingale, CH; Turley, C; Xuan, D	1
Bello, A; Christopher, L; Gajjar, DA; Ge, Z; Grasela, DM; Sukoneck, SC	1
Bell, JM; Jones, RN; Turnidge, JD	1
Citron, DM; Fernandez, H; Goldstein, EJ; Merriam, CV; Tyrrell, KL; Warren, YA	2
Boos, M; Fluit, AC; Köhrer, K; Mayer, S; Scheuring, S; Schmitz, FJ	1
Beach, ML; Gordon, KA; Jones, RN; Pfaller, MA	1
Bast, DJ; de Azavedo, JC; Duncan, CL; Kreiswirth, BN; Low, DE; McGeer, A; Muller, M; Pong-Porter, S; Willey, BM	1
Boos, M; Fluit, AC; Mayer, S; Milatovic, D; Schmitz, FJ	1
Barrett, JF; Frosco, M; Ho, H; Lawrence, LE; Mazzucco, CE; Ryan, BM; Warr, G	1
Gordon, KA; Jones, RN; Pfaller, MA	1
Gajjar, DA; Grasela, DM; Nord, CE	1
Biedenbach, DJ; Howard, W; Jones, RN	1
Appelbaum, PC; Bozdogan, B; Clark, CL; Davies, TA; Dewasse, B; Jacobs, MR; Nagai, K	1
Fung-Tomc, J; Gradelski, E; Huczko, E; Valera, L; Washo, T; Yigit, H	1
Bonner, DP; Fung-Tomc, JC; Gradelski, E; Huczko, E; Valera, L	1
Biedenbach, DJ; Jones, RN; Kirby, JT; Mutnick, AH; Pfaller, MA	1
Goldstein, EJ	1
Citron, DM; Fernandez, HT; Goldstein, EJ; Merriam, CV; Tyrrell, KL; Warren, YA	2
Cevenini, R; Donati, M; Fortugno, MT; Laghi, E; Pollini, GM; Sparacino, M	1
Finegold, S; Goldstein, E; Gorbach, SL; Harrell, L; Hecht, DW; Jacobus, NV; Jenkins, S; McDermott, LA; Pierson, C; Rihs, J; Ruthazer, R; Snydman, DR; Venezia, R	1
Bello, A; Kappel, EM; Shakibaei, M; Stahlmann, R	1
Fukumoto, H; Furubo, S; Hayakawa, H; Kawamura, Y; Kizawa, K; Miyazaki, M; Morita, T; Nagai, A; Sanzen, T	1
Hooper, DC; Ince, D; Silver, LC; Zhang, X	1
Frisbee-Hume, S; Ho, DH; LeBlanc, BM; Rolston, KV; Streeter, H	1
Lister, PD	1
Bing, X; Crabb, DM; Duffy, LB; Waites, KB	1
Barton, T; Bowlware, K; Hardy, RD; Iglehart, J; Katz, K; McCoig, CC; McCracken, GH; Michelow, IC; Rodriguez-Cerrato, V; Saavedra, J	1
Hayashi, K; Kawamura, Y; Takahata, M; Todo, Y	1
García-Rodríguez, JA; Gutiérrez Zufiaurre, N	1
Hecht, DW; Osmolski, JR	1
Drlica, K; Eisner, W; Kreiswirth, B; Perl-Rosenthal, N; Zhao, X	1
Appelbaum, PC; Jacobs, MR; Pankuch, GA	1
Andrews, J; Bello, A; Boyce, M; Gajjar, D; Honeybourne, D; Jevons, G; Wise, R	1
Appelbaum, PC; Credito, KL; Jacobs, MR	1
Fukuda, H; Kawamura, Y; Morita, Y; Nakamura, T; Soumi, K	1
Banevicius, M; Mattoes, HM; Nicolau, DP; Nightingale, CH; Xuan, D	1
Bellyou, T; Hoban, DJ; Low, DE; Nichol, KA; Palatnick, L; Zhanel, GG	1
Hammerschlag, MR; Reznik, T; Roblin, PM	1
Anderegg, TR; Biedenbach, DJ; Jones, RN	1
Bello, A; Christopher, L; Gajjar, DA; Ge, Z; Grasela, DM	1
Ameyama, S; Shinmura, Y; Takahata, M	1
Bello, A; Gajjar, DA; Grasela, DM; Meurling, L; Nord, CE; Russo, RL	1
Almaraz, F; Baquero, F; Cantón, R; del Campo, R; Loza, E; Morosini, MI	1
Gordon, KA; Jones, RN; Rhomberg, PR	1
Aracil, B; Campos, J; Cantón, R; Pérez-Vázquez, M; Román, F	1
Aubert, A; Grohs, P; Gutmann, L; Houssaye, S; Varon, E	1
Bébéar, C; Bébéar, CM; Pereyre, S; Renaudin, H	1
Michot, JM; Mingeot-Leclercq, MP; Seral, C; Tulkens, PM; Van Bambeke, F	1
Brown, DL; Drusano, GL; Liu, W; Louie, A; Rice, LB	1
Brandenburg, K; Grüger, T; Reiners, AL; Schnitzler, N; Zündorf, J	1
Fukuda, Y; Nomura, N; Shinmura, Y; Sugiura, Y; Takahata, M	1
Mizunaga, S; Nakatani, M; Nomura, N; Takahata, M	1
Aubry, A; Chauffour, A; Escolano, S; Henquet, S; Jarlier, V; Matsuoka, M; Veziris, N	1
Hsu, MC; Leunk, R; Makin, K; Roychoudhury, S; Twinem, T	1
Mikamo, H; Mitsuyama, J; Nakagawa, S; Nomura, N; Shibata, T; Yamagishi, Y	1
Hasegawa, H; Izumikawa, K; Kaku, N; Kosai, K; Miyazaki, T; Morinaga, Y; Mukae, H; Murata, M; Sasaki, D; Uno, N; Yamauchi, S; Yanagihara, K	1
Fukuda, Y; Fukushima, K; Hashiguchi, K; Higashiyama, Y; Imamura, Y; Inoue, Y; Izumikawa, K; Kobayashi, T; Koga, H; Kohno, S; Kondo, A; Mikushi, S; Miyazaki, T; Morinaga, Y; Mukae, H; Nagayoshi, Y; Nakamura, S; Saijo, T; Sasaki, E; Takazono, T; Yamamoto, K; Yanagihara, K; Yoshida, M	1

Trials

6 trial(s) available for garenoxacin and carbostyril

Article	Year
Single-dose pharmacokinetics and penetration of BMS 284756 into an inflammatory exudate. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:1 Topics: Adult; Anti-Infective Agents; Cantharidin; Fluoroquinolones; Humans; Indoles; Inflammation; Male; Metabolic Clearance Rate; Quinolones	2002
Effect of a high-fat meal on the pharmacokinetics of the des-F(6)-quinolone BMS-284756. Pharmacotherapy, 2002, Volume: 22, Issue:2 Topics: Administration, Oral; Adult; Anti-Infective Agents; Area Under Curve; Biological Availability; Chromatography, Liquid; Cross-Over Studies; Dietary Fats; Drug Interactions; Fasting; Female; Fluoroquinolones; Half-Life; Humans; Indoles; Male; Mass Spectrometry; Quinolones	2002
Ecological impact of the des-F(6)-quinolone, BMS-284756, on the normal intestinal microflora. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2002, Volume: 8, Issue:4 Topics: Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Enterobacteriaceae; Feces; Female; Fluoroquinolones; Humans; Indoles; Intestines; Male; Microbial Sensitivity Tests; Middle Aged; Placebos; Quinolones	2002
Multiple-dose safety and pharmacokinetics of oral garenoxacin in healthy subjects. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:7 Topics: Administration, Oral; Adult; Electrocardiography; Fluoroquinolones; Helicobacter Infections; Helicobacter pylori; Humans; Indoles; Placebos; Psychometrics; Quinolones	2003
Effect of garenoxacin on eubacteria in the normal intestinal microflora when administered concomitantly with digoxin. Journal of chemotherapy (Florence, Italy), 2003, Volume: 15, Issue:3 Topics: Administration, Oral; Adolescent; Biological Availability; Colony Count, Microbial; Digoxin; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Eubacterium; Feces; Female; Fluoroquinolones; Gram-Positive Bacterial Infections; Humans; Indoles; Intestinal Mucosa; Male; Microbial Sensitivity Tests; Prospective Studies; Quinolones; Sensitivity and Specificity	2003
The efficacy and safety of sitafloxacin and garenoxacin for the treatment of pneumonia in elderly patients: A randomized, multicenter, open-label trial. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2019, Volume: 25, Issue:11 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Community-Acquired Infections; Female; Fluoroquinolones; Humans; Japan; Male; Pneumonia; Quinolones	2019

Other Studies

83 other study(ies) available for garenoxacin and carbostyril

Article	Year
Antibacterial spectrum of a novel des-fluoro(6) quinolone, BMS-284756. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:12 Topics: Anti-Infective Agents; Bacteria, Anaerobic; Fluoroquinolones; Gram-Negative Aerobic Bacteria; Gram-Positive Bacteria; Indoles; Microbial Sensitivity Tests; Quinolones	2000
Comparative antianaerobic activity of BMS 284756. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:2 Topics: Anti-Infective Agents; Bacteria, Anaerobic; beta-Lactamase Inhibitors; Clavulanic Acid; Drug Resistance, Microbial; Enzyme Inhibitors; Fluoroquinolones; Indoles; Microbial Sensitivity Tests; Quinolones	2001
Activity and spectrum of BMS 284756, a new des-F (6) quinolone, tested against strains of ciprofloxacin-resistant Gram-positive cocci. Diagnostic microbiology and infectious disease, 2001, Volume: 39, Issue:2 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Indoles; Microbial Sensitivity Tests; Quinolones	2001
Activities of BMS 284756 (T-3811) against Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae isolates from SENTRY antimicrobial surveillance program medical centers in Latin America (1999). Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:5 Topics: Anti-Infective Agents; Fluoroquinolones; Haemophilus influenzae; Humans; Indoles; Latin America; Microbial Sensitivity Tests; Moraxella catarrhalis; Quinolones; Sentinel Surveillance; Streptococcus pneumoniae	2001
Activity of BMS284756 against 2,681 recent clinical isolates of Haemophilus influenzae and Moraxella catarrhalis: Report from The SENTRY Antimicrobial Surveillance Program (2000) in Europe, Canada and the United States. Diagnostic microbiology and infectious disease, 2001, Volume: 39, Issue:4 Topics: Anti-Infective Agents; Aza Compounds; Canada; Ciprofloxacin; Europe; Fluoroquinolones; Gatifloxacin; Haemophilus influenzae; Humans; Indoles; Levofloxacin; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; United States	2001
Comparative killing kinetics of the novel des-fluoro(6) quinolone BMS-284756, fluoroquinolones, vancomycin and beta-lactams. International journal of antimicrobial agents, 2001, Volume: 18, Issue:1 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; beta-Lactams; Enterobacteriaceae; Enterococcus faecalis; Fluoroquinolones; Indoles; Kinetics; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Staphylococcus aureus; Streptococcus; Vancomycin	2001
The inhibition and selectivity of bacterial topoisomerases by BMS-284756 and its analogues. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:2 Topics: Anti-Infective Agents; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Escherichia coli; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Quinolones; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors	2001
In vitro susceptibility testing of BMS-284756 by the BSAC standardized disc testing method. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:2 Topics: Anti-Infective Agents; Bacteria; Bacteriological Techniques; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Quinolones	2001
Comparative antimicrobial spectrum and activity of BMS284756 (T-3811, a desfluoroquinolone) tested against 656 Enterobacteriaceae, including preliminary in vitro susceptibility test comparisons and development. International journal of antimicrobial agents, 2001, Volume: 18, Issue:2 Topics: Anti-Infective Agents; Enterobacteriaceae; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Quinolones	2001
Intracellular penetration and bactericidal activity of the novel des-fluoro(6) quinolone, BMS-284756. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:3 Topics: Animals; Anti-Infective Agents; Biological Transport; Cells, Cultured; Fluoroquinolones; Humans; Indoles; Mice; Microbial Sensitivity Tests; Phagocytes; Quinolones; Staphylococcus	2001
Comparison of the in vitro activities of BMS-284756 and four fluoroquinolones against Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:3 Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Moxifloxacin; Norfloxacin; Quinolines; Quinolones; Streptococcus pneumoniae	2001
Selection and genetic characterization of Streptococcus pneumoniae mutants resistant to the des-F(6) quinolone BMS-284756. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:10 Topics: Anti-Infective Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Microbial; Fluoroquinolones; Indoles; Microbial Sensitivity Tests; Mutation; Polymerase Chain Reaction; Quinolones; Selection, Genetic; Streptococcus pneumoniae	2001
Induction of in vitro resistance to BMS-284756 by Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:4 Topics: Anti-Infective Agents; Culture Media; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Mutation; Pneumococcal Infections; Quinolones; Streptococcus pneumoniae	2001
BMS-284756 in experimental cephalosporin-resistant pneumococcal meningitis. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:11 Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ceftriaxone; Cephalosporin Resistance; Fluoroquinolones; Indoles; Male; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Penicillin Resistance; Quinolones; Rabbits; Vancomycin	2001
Staphylococcus aureus mutants selected by BMS-284756. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:11 Topics: Anti-Infective Agents; Ciprofloxacin; DNA Gyrase; DNA, Bacterial; Drug Resistance, Microbial; Fluoroquinolones; Indoles; Mutation; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcus aureus	2001
BMS-284756 (T-3811ME) a new fluoroquinolone: in vitro activity against Legionella, efficacy in a guinea pig model of L. pneumophila pneumonia and pharmacokinetics in guinea pigs. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:5 Topics: Animals; Anti-Infective Agents; Culture Media; Disease Models, Animal; Fluoroquinolones; Guinea Pigs; Indoles; Legionella pneumophila; Legionnaires' Disease; Male; Quinolones	2001
Activity of the novel des-fluoro(6) quinolone BMS-284756 against methicillin-susceptible and -resistant staphylococci. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:5 Topics: Anti-Infective Agents; Fluoroquinolones; Humans; Indoles; Methicillin; Methicillin Resistance; Penicillins; Quinolones; Staphylococcus	2001
Antimicrobial activity of BMS 284756, a novel des-fluoro (6) quinolone and seven fluoroquinolones against Streptococcus pneumoniae. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2001, Volume: 7, Issue:10 Topics: Anti-Infective Agents; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Quinolones; Streptococcus pneumoniae	2001
Mechanism of action of the des-F(6) quinolone BMS-284756 measured by supercoiling inhibition and cleavable complex assays. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:12 Topics: Anti-Infective Agents; DNA, Bacterial; DNA, Superhelical; Enzyme Inhibitors; Escherichia coli; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Indoles; Microbial Sensitivity Tests; Quinolones; Topoisomerase II Inhibitors	2001
Antimicrobial activity of BMS 284756 (T-3811) against Neisseria gonorrhoeae tested by three methods. International journal of antimicrobial agents, 2001, Volume: 18, Issue:5 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gonorrhea; Humans; Indoles; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillin Resistance; Penicillins; Quinolones	2001
Efficacies of BMS 284756 against penicillin-sensitive, penicillin-resistant, and quinolone-resistant pneumococci in experimental meningitis. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:1 Topics: 4-Quinolones; Animals; Anti-Infective Agents; Disease Models, Animal; Fluoroquinolones; Indoles; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Penicillin Resistance; Quinolones; Rabbits; Streptococcus pneumoniae; Treatment Outcome	2002
Bactericidal activities of BMS-284756, a novel Des-F(6)-quinolone, against Staphylococcus aureus strains with topoisomerase mutations. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:1 Topics: Anti-Infective Agents; Aza Compounds; DNA Topoisomerases, Type I; Fluoroquinolones; Indoles; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Ofloxacin; Quinolines; Quinolones; Staphylococcus aureus	2002
Antimicrobial activities of BMS-284756 compared with those of fluoroquinolones and beta-lactams against gram-positive clinical isolates. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:1 Topics: Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactams; Fluoroquinolones; Gram-Positive Bacteria; Humans; Indoles; Microbial Sensitivity Tests; Quinolones	2002
Antipneumococcal activity of BMS 284756 compared to those of six other agents. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:1 Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Penicillin Resistance; Quinolones; Streptococcus pneumoniae; Time Factors	2002
The in vitro activity of BMS-284756, a new des-fluorinated quinolone. The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:1 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Indoles; Lactams; Microbial Sensitivity Tests; Quinolones; Serum Bactericidal Test	2002
Assessment of BMS284756 MIC and 5-microg disk diffusion quality control studies tested against seven American type culture collection strains. Diagnostic microbiology and infectious disease, 2001, Volume: 41, Issue:4 Topics: Anti-Infective Agents; Enterococcus faecalis; Escherichia coli; Fluoroquinolones; Haemophilus influenzae; Indoles; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Quality Control; Quinolones; Staphylococcus aureus; Streptococcus pneumoniae	2001
In vitro activities of BMS-284756 against Chlamydia trachomatis and recent clinical isolates of Chlamydia pneumoniae. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:2 Topics: Anti-Infective Agents; Chlamydia trachomatis; Chlamydophila pneumoniae; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Quinolones	2002
Increased in vitro activity of the novel des-fluoro(6) quinolone BMS-284756 against genetically defined clinical isolates of Staphylococcus aureus. The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:2 Topics: Anti-Infective Agents; Drug Evaluation, Preclinical; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Quinolones; Staphylococcus aureus	2002
Determination of BMS-284756, a new quinolone, in mouse serum by high-performance liquid chromatography with fluorescence detection. Journal of chromatography. B, Biomedical sciences and applications, 2001, Dec-05, Volume: 765, Issue:1 Topics: Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Fluoroquinolones; Indoles; Mice; Quinolones; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence	2001
Antimicrobial resistance trends in community-acquired respiratory tract pathogens in the Western Pacific Region and South Africa: report from the SENTRY antimicrobial surveillance program, (1998-1999) including an in vitro evaluation of BMS284756. International journal of antimicrobial agents, 2002, Volume: 19, Issue:2 Topics: Anti-Infective Agents; Asia; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Haemophilus Infections; Haemophilus influenzae; Humans; Indoles; Microbial Sensitivity Tests; Moraxella catarrhalis; Neisseriaceae Infections; Pneumococcal Infections; Population Surveillance; Prevalence; Quinolones; Respiratory Tract Diseases; South Africa; Streptococcus pneumoniae	2002
In vitro activities of the des-fluoro(6) Quinolone BMS-284756 against aerobic and anaerobic pathogens isolated from skin and soft tissue animal and human bite wound infections. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:3 Topics: Animals; Anti-Infective Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bites and Stings; Cats; Dogs; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Quinolones; Skin Diseases, Infectious; Soft Tissue Infections	2002
In vitro activities of novel des-fluoro(6) quinolone BMS-284756 against mutants of Streptococcus pneumoniae, Streptococcus pyogenes, and Staphylococcus aureus selected with different quinolones. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:3 Topics: Anti-Infective Agents; DNA Topoisomerase IV; Drug Resistance, Microbial; Fluoroquinolones; Indoles; Microbial Sensitivity Tests; Quinolones; Staphylococcus aureus; Streptococcus pneumoniae; Streptococcus pyogenes	2002
Comparative antimicrobial spectrum and activity of BMS284756 (T-3811; a desfluoroquinolone) tested against an international collection of staphylococci and enterococci, including in vitro test development and intermethod comparisons. Journal of chemotherapy (Florence, Italy), 2002, Volume: 14, Issue:1 Topics: Anti-Infective Agents; Drug Resistance, Bacterial; Enterococcus; Fluoroquinolones; Indoles; Microbial Sensitivity Tests; Quinolones; Staphylococcus	2002
Activity of BMS-284756, a novel des-fluoro(6) quinolone, against Staphylococcus aureus, including contributions of mutations to quinolone resistance. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:4 Topics: Amino Acid Substitution; Anti-Infective Agents; DNA Gyrase; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Microbial; Fluoroquinolones; Humans; Indoles; Methicillin Resistance; Microbial Sensitivity Tests; Mutation; Quinolones; Staphylococcal Infections; Staphylococcus aureus; Topoisomerase II Inhibitors	2002
In vitro activities of a new des-fluoroquinolone, BMS 284756, and seven other antimicrobial agents against 151 isolates of Eikenella corrodens. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:4 Topics: Anti-Infective Agents; Drug Resistance, Microbial; Eikenella corrodens; Fluoroquinolones; Gram-Negative Bacterial Infections; Humans; Indoles; Microbial Sensitivity Tests; Quinolones	2002
In vitro activity of the novel des-F(6) quinolone BMS-284756 against genetically characterized clinical streptococcal isolates, including isolates with reduced quinolone susceptibility. The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:4 Topics: Anti-Infective Agents; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Quinolones; Streptococcus	2002
Comparison of the bactericidal activities and post-antibiotic effects of the Des-F(6)-quinolone BMS-284756, levofloxacin, and ciprofloxacin against methicillin-susceptible and methicillin-resistant Staphylococcus aureus. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2002, Volume: 21, Issue:1 Topics: Anti-Infective Agents; Blood Bactericidal Activity; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Indoles; Levofloxacin; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Quinolones; Sensitivity and Specificity; Staphylococcus aureus	2002
BMS284756 (formerly T-3811, a des-fluoroquinolone) potency and spectrum tested against over 10,000 bacterial bloodstream infection isolates from the SENTRY antimicrobial surveillance programme (2000). The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:5 Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Drug Resistance, Microbial; Fluoroquinolones; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Indoles; Microbial Sensitivity Tests; Population Surveillance; Quinolones	2002
Comparative antimicrobial spectrum and activity of the desfluoroquinolone BMS284756 (T-3811) tested against non-fermentative Gram-negative bacilli. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2002, Volume: 8, Issue:6 Topics: Anti-Infective Agents; Bacillus; Fluoroquinolones; Gram-Negative Bacteria; Humans; Indoles; Microbial Sensitivity Tests; Quinolones	2002
Single- and multistep selection study of the antipneumococcal activity of BMS-284756 compared to ciprofloxacin, levofloxacin, trovafloxacin and moxifloxacin. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2002, Volume: 8, Issue:6 Topics: Anti-Infective Agents; Aza Compounds; Biological Transport; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Humans; Indoles; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Streptococcus pneumoniae	2002
In vitro activity of a novel des-fluoro(6) quinolone, garenoxacin (BMS-284756), against rapidly growing mycobacteria and Nocardia isolates. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:1 Topics: Anti-Bacterial Agents; Fluoroquinolones; Indoles; Microbial Sensitivity Tests; Mycobacterium; Nocardia; Quinolones; Species Specificity	2002
Synergistic activity of the novel des-fluoro(6) quinolone, garenoxacin (BMS-284756), in combination with other antimicrobial agents against Pseudomonas aeruginosa and related species. International journal of antimicrobial agents, 2002, Volume: 20, Issue:1 Topics: Anti-Infective Agents; Drug Combinations; Drug Synergism; Fluoroquinolones; Gram-Negative Aerobic Bacteria; Indoles; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Quinolones	2002
Geographic variations in garenoxacin (BMS284756) activity tested against pathogens associated with skin and soft tissue infections: report from the SENTRY Antimicrobial Surveillance Program (2000). Diagnostic microbiology and infectious disease, 2002, Volume: 43, Issue:4 Topics: Anti-Infective Agents; Bacteria; Drug Resistance, Bacterial; Europe; Fluoroquinolones; Humans; Indoles; Latin America; Microbial Sensitivity Tests; North America; Population Surveillance; Quinolones; Skin Diseases, Bacterial; Soft Tissue Infections	2002
Intra-abdominal anaerobic infections: bacteriology and therapeutic potential of newer antimicrobial carbapenem, fluoroquinolone, and desfluoroquinolone therapeutic agents. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Sep-01, Volume: 35, Issue:Suppl 1 Topics: Abdominal Abscess; Anti-Bacterial Agents; Aza Compounds; Bacteremia; Bacteria, Anaerobic; Bacteroides fragilis; Bacteroides Infections; beta-Lactams; Carbapenems; Clinical Trials as Topic; Ertapenem; Fluoroquinolones; Gemifloxacin; Humans; Indoles; Lactams; Moxifloxacin; Naphthyridines; Quinolines; Quinolones	2002
In vitro activities of garenoxacin (BMS-284756) against 170 clinical isolates of nine Pasteurella species. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:9 Topics: Anti-Infective Agents; Bites and Stings; Culture Media; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Pasteurella; Pasteurella Infections; Quinolones; United States	2002
Comparative in vitro activity of garenoxacin against Chlamydia spp. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:3 Topics: Animals; Anti-Bacterial Agents; Chlamydia Infections; Chlamydia trachomatis; Chlamydophila pneumoniae; Chlamydophila psittaci; Fluoroquinolones; Humans; Indoles; Macrolides; Microbial Sensitivity Tests; Quinolones; Tetracyclines	2002
In vitro activities of newer quinolones against bacteroides group organisms. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:10 Topics: Anti-Infective Agents; Aza Compounds; Bacteroides; Bacteroides fragilis; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Quinolines; Quinolones	2002
Effects of the Des-F(6)-quinolone garenoxacin (BMS-284756), in comparison to those of ciprofloxacin and ofloxacin, on joint cartilage in immature rats. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:10 Topics: Administration, Oral; Animals; Anti-Infective Agents; Cartilage Diseases; Cartilage, Articular; Ciprofloxacin; Fluoroquinolones; Indoles; Knee Joint; Ofloxacin; Quinolones; Rats; Rats, Wistar	2002
Comparative articular toxicity of garenoxacin, a novel quinolone antimicrobial agent, in juvenile beagle dogs. The Journal of toxicological sciences, 2002, Volume: 27, Issue:3 Topics: Administration, Oral; Animals; Anti-Infective Agents; Cartilage, Articular; Ciprofloxacin; Dogs; Dose-Response Relationship, Drug; Female; Fluoroquinolones; Indoles; Injections, Intravenous; Joint Diseases; Male; Norfloxacin; Quinolones; Toxicity Tests	2002
Dual targeting of DNA gyrase and topoisomerase IV: target interactions of garenoxacin (BMS-284756, T-3811ME), a new desfluoroquinolone. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:11 Topics: Alleles; Anti-Infective Agents; Ciprofloxacin; Cloning, Molecular; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gene Expression Regulation, Enzymologic; Indoles; Microbial Sensitivity Tests; Mutation; Plasmids; Quinolones; Staphylococcus aureus; Topoisomerase II Inhibitors	2002
In vitro activities of Garenoxacin (BMS 284756) against 108 clinical isolates of Gardnerella vaginalis. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:12 Topics: Drug Resistance, Bacterial; Fluoroquinolones; Gardnerella vaginalis; Indoles; Microbial Sensitivity Tests; Quinolones	2002
Antimicrobial activity of a novel des-fluoro (6) quinolone, garenoxacin (BMS-284756), compared to other quinolones, against clinical isolates from cancer patients. Diagnostic microbiology and infectious disease, 2002, Volume: 44, Issue:2 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Female; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Indoles; Levofloxacin; Male; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Sensitivity and Specificity	2002
Impact of AUC/MIC ratios on the pharmacodynamics of the des-F(6) quinolone garenoxacin (BMS-284756) is similar to other fluoroquinolones. The Journal of antimicrobial chemotherapy, 2003, Volume: 51, Issue:1 Topics: Anti-Infective Agents; Area Under Curve; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Quinolones; Streptococcus pneumoniae	2003
In vitro susceptibilities to and bactericidal activities of garenoxacin (BMS-284756) and other antimicrobial agents against human mycoplasmas and ureaplasmas. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:1 Topics: Anti-Bacterial Agents; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Mycoplasma; Quinolones; Ureaplasma	2003
Garenoxacin (BMS-284756) and moxifloxacin in experimental meningitis caused by vancomycin-tolerant pneumococci. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:1 Topics: Animals; Anti-Infective Agents; Aza Compounds; Fluoroquinolones; Indoles; Male; Meningitis, Bacterial; Microbial Sensitivity Tests; Moxifloxacin; Quinolines; Quinolones; Rabbits; Streptococcus pneumoniae; Vancomycin; Vancomycin Resistance	2003
Synthesis, antibacterial activity, and toxicity of 7-(isoindolin-5-yl)-4-oxoquinoline-3-carboxylic acids. Discovery of the novel des-F(6)-quinolone antibacterial agent garenoxacin (T-3811 or BMS-284756). Arzneimittel-Forschung, 2002, Volume: 52, Issue:12 Topics: Animals; Anti-Infective Agents; Bacteria; Fluoroquinolones; Indicators and Reagents; Indoles; Injections, Intraventricular; Magnetic Resonance Spectroscopy; Mice; Microbial Sensitivity Tests; Micronucleus Tests; Mutagens; Quinolones; Seizures; Structure-Activity Relationship	2002
[Desfluoroquinolones vs. fluoroquinolones]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2002, Volume: 15, Issue:4 Topics: Animals; Anti-Infective Agents; Fluoroquinolones; Indoles; Quinolones	2002
Activities of garenoxacin (BMS-284756) and other agents against anaerobic clinical isolates. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:3 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria, Anaerobic; Bacterial Infections; Chicago; Culture Media; Fluoroquinolones; Indoles; Microbial Sensitivity Tests; Quinolones	2003
Mutant prevention concentration of garenoxacin (BMS-284756) for ciprofloxacin-susceptible or -resistant Staphylococcus aureus. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:3 Topics: Anti-Infective Agents; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Mutation; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcal Infections; Staphylococcus aureus	2003
Postantibiotic effects of garenoxacin (BMS-284756) against 12 gram-positive or -negative organisms. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:3 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Colony Count, Microbial; Culture Media; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Indoles; Microbial Sensitivity Tests; Quinolones; Time Factors	2003
Concentrations of garenoxacin in plasma, bronchial mucosa, alveolar macrophages and epithelial lining fluid following a single oral 600 mg dose in healthy adult subjects. The Journal of antimicrobial chemotherapy, 2003, Volume: 51, Issue:3 Topics: Administration, Oral; Adult; Bronchi; Bronchoalveolar Lavage Fluid; Female; Fluoroquinolones; Humans; Indoles; Macrophages, Alveolar; Male; Quinolones; Respiratory Mucosa	2003
Time-kill studies of the antianaerobe activity of garenoxacin compared with those of nine other agents. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:4 Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Fluoroquinolones; Humans; Indoles; Microbial Sensitivity Tests; Quinolones	2003
Pharmacological evaluation of garenoxacin, a novel des-F(6)-quinolone antimicrobial agent: effects on the central nervous system. The Journal of toxicological sciences, 2003, Volume: 28, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System; Drug Interactions; Fluoroquinolones; gamma-Aminobutyric Acid; Injections, Intravenous; Injections, Intraventricular; Male; Mice; Models, Animal; Quinolones; Rats; Rats, Wistar; Receptors, GABA; Seizures	2003
Pharmacodynamics of a novel des-F(6)-quinolone, BMS-284756, against Streptococcus pneumoniae in the thigh infection model. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:5 Topics: Animals; Anti-Infective Agents; Area Under Curve; Disease Models, Animal; Fluoroquinolones; Indoles; Mice; Mice, Inbred CBA; Mice, Inbred ICR; Microbial Sensitivity Tests; Pneumococcal Infections; Protein Binding; Quinolones; Streptococcus pneumoniae; Thigh	2003
Comparative activity of garenoxacin (BMS 284756), a novel desfluoroquinolone, tested against 8,331 isolates from community-acquired respiratory tract infections: North American results from the SENTRY Antimicrobial Surveillance Program (1999-2001). Diagnostic microbiology and infectious disease, 2003, Volume: 45, Issue:4 Topics: Anti-Bacterial Agents; Community-Acquired Infections; Drug Resistance, Microbial; Female; Fluoroquinolones; Haemophilus influenzae; Humans; Indoles; Male; Microbial Sensitivity Tests; Moraxella catarrhalis; North America; Quinolones; Respiratory Tract Infections; Sensitivity and Specificity; Streptococcus pneumoniae	2003
Antimicrobial resistance in respiratory tract Streptococcus pneumoniae isolates: results of the Canadian Respiratory Organism Susceptibility Study, 1997 to 2002. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:6 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; beta-Lactam Resistance; Canada; Drug Resistance, Multiple, Bacterial; Erythromycin; Female; Fluoroquinolones; Humans; Indoles; Ketolides; Longitudinal Studies; Male; Microbial Sensitivity Tests; Middle Aged; Minocycline; Pneumococcal Infections; Quinolones; Respiratory Tract Infections; Streptococcus pneumoniae; Tigecycline	2003
In vitro activity of garenoxacin against recent clinical isolates of Chlamydia pneumoniae. International journal of antimicrobial agents, 2003, Volume: 21, Issue:6 Topics: Adult; Anti-Infective Agents; Canada; Chlamydophila Infections; Chlamydophila pneumoniae; Community-Acquired Infections; Fluoroquinolones; Humans; Indoles; Japan; Microbial Sensitivity Tests; Pneumonia, Bacterial; Quinolones; United States	2003
Re-evaluation of quality control guidelines for gatifloxacin and garenoxacin (BMS284756) when susceptibility testing Haemophilus influenzae and Streptococcus pneumoniae. Diagnostic microbiology and infectious disease, 2003, Volume: 46, Issue:2 Topics: Anti-Infective Agents; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Guidelines as Topic; Haemophilus influenzae; Humans; Indoles; Microbial Sensitivity Tests; Quality Control; Quinolones; Sensitivity and Specificity; Streptococcus pneumoniae	2003
Inhibitory activities of quinolones against DNA gyrase of Chlamydia pneumoniae. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:7 Topics: Anti-Infective Agents; Aza Compounds; Chlamydophila pneumoniae; DNA Gyrase; Fluoroquinolones; Gatifloxacin; Genes, Bacterial; Indoles; Levofloxacin; Molecular Sequence Data; Moxifloxacin; Ofloxacin; Quinolines; Quinolones; Topoisomerase II Inhibitors	2003
Fluoroquinolone-resistant Streptococcus pneumoniae in Spain: activities of garenoxacin against clinical isolates including strains with altered topoisomerases. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:8 Topics: Anti-Infective Agents; DNA Gyrase; DNA Topoisomerases; DNA, Bacterial; Drug Resistance, Bacterial; Fluoroquinolones; Genes, Bacterial; Humans; Indoles; Methyltransferases; Microbial Sensitivity Tests; Pneumococcal Infections; Prospective Studies; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; Spain; Streptococcus pneumoniae	2003
Commercial broth microdilution panel validation and reproducibility trials for garenoxacin (BMS-284756), a novel desfluoroquinolone. Journal of clinical microbiology, 2003, Volume: 41, Issue:8 Topics: Anti-Infective Agents; Culture Media; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacteria; Indoles; Microbial Sensitivity Tests; Quinolones; Reagent Kits, Diagnostic; Reproducibility of Results	2003
In vitro activities of garenoxacin (BMS-284756) against Haemophilus influenzae isolates with different fluoroquinolone susceptibilities. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:11 Topics: Amino Acid Substitution; Anti-Infective Agents; DNA Gyrase; DNA Topoisomerase IV; Fluoroquinolones; Haemophilus Infections; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Mutation; Quinolones; Reverse Transcriptase Polymerase Chain Reaction	2003
In vitro activities of garenoxacin (BMS-284756) against Streptococcus pneumoniae, viridans group streptococci, and Enterococcus faecalis compared to those of six other quinolones. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:11 Topics: Anti-Bacterial Agents; Colony Count, Microbial; Drug Resistance, Bacterial; Enterococcus faecalis; Fluoroquinolones; Genes, Bacterial; Microbial Sensitivity Tests; Quinolones; Streptococcus oralis; Streptococcus pneumoniae; Viridans Streptococci	2003
In vitro activities of the newer quinolones garenoxacin, gatifloxacin, and gemifloxacin against human mycoplasmas. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:8 Topics: Anti-Infective Agents; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Microbial Sensitivity Tests; Mycoplasma; Mycoplasma Infections; Naphthyridines; Quinolones	2004
Influence of efflux transporters on the accumulation and efflux of four quinolones (ciprofloxacin, levofloxacin, garenoxacin, and moxifloxacin) in J774 macrophages. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:6 Topics: Anti-Infective Agents; Aza Compounds; Cell Line; Ciprofloxacin; Fluoroquinolones; Heat-Shock Response; Humans; Kinetics; Levofloxacin; Macrophages; Moxifloxacin; Ofloxacin; Quinolines; Quinolones	2005
Impact of short-course quinolone therapy on susceptible and resistant populations of Staphylococcus aureus. The Journal of infectious diseases, 2009, Jan-15, Volume: 199, Issue:2 Topics: Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Models, Biological; Quinolones; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome	2009
Garenoxacin-induced increase of CD11b expression on human polymorphonuclear neutrophils does not affect phagocytosis and killing of Staphylococcus aureus. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2011, Volume: 17, Issue:2 Topics: Anti-Bacterial Agents; CD11b Antigen; Colony Count, Microbial; Flow Cytometry; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Neutrophils; Phagocytosis; Quinolones; Respiratory Burst; Staphylococcal Infections; Staphylococcus aureus; Up-Regulation	2011
In vitro pharmacodynamic evaluation of garenoxacin against quinolone-resistant Streptococcus pneumoniae. International journal of antimicrobial agents, 2012, Volume: 39, Issue:2 Topics: Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Microbial Viability; Mutation, Missense; Quinolones; Streptococcus pneumoniae; Time Factors	2012
Inhibitory activity of garenoxacin against DNA gyrase of Mycoplasma pneumoniae. The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:8 Topics: Anti-Bacterial Agents; DNA Gyrase; Enzyme Inhibitors; Escherichia coli; Fluoroquinolones; Gene Expression; Inhibitory Concentration 50; Mycoplasma pneumoniae; Plasmids; Protein Subunits; Quinolones; Recombinant Proteins; Topoisomerase II Inhibitors	2012
Resistance of M. leprae to quinolones: a question of relativity? PLoS neglected tropical diseases, 2013, Volume: 7, Issue:11 Topics: Animals; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Leprosy; Mice; Moxifloxacin; Mycobacterium leprae; Quinolines; Quinolones	2013
In Vitro Resistance Development to Nemonoxacin in Streptococcus pneumoniae: A Unique Profile for a Novel Nonfluorinated Quinolone. Microbial drug resistance (Larchmont, N.Y.), 2016, Volume: 22, Issue:7 Topics: Anti-Bacterial Agents; Ciprofloxacin; Culture Media; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gatifloxacin; Gene Expression; Microbial Sensitivity Tests; Mutation; Quinolones; Sequence Analysis, DNA; Streptococcus pneumoniae; Structure-Activity Relationship	2016
Proposed Pharmacokinetic-Pharmacodynamic Breakpoint of Garenoxacin and Other Quinolones. Japanese journal of infectious diseases, 2017, Nov-22, Volume: 70, Issue:6 Topics: Administration, Oral; Anti-Bacterial Agents; Area Under Curve; Community-Acquired Infections; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Monte Carlo Method; Pneumonia, Bacterial; Quinolones; Streptococcus pneumoniae	2017
Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:4 Topics: Drug Resistance, Bacterial; Fluoroquinolones; Levofloxacin; Microbial Sensitivity Tests; Mutation; Quinolones; Streptococcus pneumoniae	2018