ganoderic-acid-a and ergosterol-5-8-peroxide

To study the chemical constituents of the sporoderm-broken spores of Ganoderma lucidum.. Chemical constituents were isolated and purified by silica gel and Sephadex LH-20 column chromatography. The structures were identified by means of physicochemical and spectral data.. From the ethyl acetate extract of the material, eight compounds were isolated. Their structures were identified as ganoderic acid A (I), methyl ganoderate A (II), methyl ganoderate B (III), ganoderic acid C2 (IV), ganoderic acid G(V), ergosta-7,22-diene-3beta, 5alpha, 6beta-triol (VI), ergosterol peroxide (VII) and ergosta-7,22-diene-3beta-yl pentadecanoate (VIII), respectively.. Compounds II, III, VII and VIII are isolated from the spores of G. lucidum for the first time.

Topics: Ergosterol; Ganoderma; Heptanoic Acids; Lanosterol; Magnetic Resonance Spectroscopy; Molecular Structure; Spores, Fungal; Triterpenes