ganglioside--gm4 and hydroxide-ion

ganglioside--gm4 has been researched along with hydroxide-ion* in 1 studies

Other Studies

1 other study(ies) available for ganglioside--gm4 and hydroxide-ion

Article	Year
Chemical approach for the syntheses of GM4 isomers with sialic acid to non-natural linkage positions on galactose. Carbohydrate research, 2015, Jan-12, Volume: 401 Cell-surface glycans containing sialic acid are involved in various biological phenomena. However, the syntheses of GM4 derivatives with (2 → 2) and (2 → 4) linkages have not been investigated to date. In this study, sialylation of all of the hydroxyl groups on galactose were investigated for the syntheses of GM4 isomers. Regioselective sialylation was achieved via protection of galactosyl acceptors using electron-rich benzyl groups. These synthetic sialylated glycans will prove to be useful tools for studying unidentified carbohydrate-mediated biological roles. Topics: Chemistry Techniques, Synthetic; Galactose; Gangliosides; Glycosylation; Hydroxides; N-Acetylneuraminic Acid; Stereoisomerism; Substrate Specificity	2015

Article

Year

Chemical approach for the syntheses of GM4 isomers with sialic acid to non-natural linkage positions on galactose.

Carbohydrate research, 2015, Jan-12, Volume: 401

Cell-surface glycans containing sialic acid are involved in various biological phenomena. However, the syntheses of GM4 derivatives with (2 → 2) and (2 → 4) linkages have not been investigated to date. In this study, sialylation of all of the hydroxyl groups on galactose were investigated for the syntheses of GM4 isomers. Regioselective sialylation was achieved via protection of galactosyl acceptors using electron-rich benzyl groups. These synthetic sialylated glycans will prove to be useful tools for studying unidentified carbohydrate-mediated biological roles.

Topics: Chemistry Techniques, Synthetic; Galactose; Gangliosides; Glycosylation; Hydroxides; N-Acetylneuraminic Acid; Stereoisomerism; Substrate Specificity

2015