ganglioside--gd1a and 1-2-oleoylphosphatidylcholine

ganglioside--gd1a has been researched along with 1-2-oleoylphosphatidylcholine* in 1 studies

Other Studies

1 other study(ies) available for ganglioside--gd1a and 1-2-oleoylphosphatidylcholine

Article	Year
Modulation by gangliosides of the lamellar-inverted micelle (hexagonal II) phase transition in mixtures containing phosphatidylethanolamine and dioleoylglycerol. Proceedings of the National Academy of Sciences of the United States of America, 1994, Oct-11, Volume: 91, Issue:21 We studied the effect of gangliosides GD1a and GM1 on the lamellar-to-hexagonal II phase transition of mixtures of dioleoylphosphatidylethanolamine/dioleoylphosphatidyl choline, 3:1, and of transphosphatidylated phosphatidylethanolamine with dioleoylglycerol by high-sensitivity differential scanning calorimetry, 31P-NMR, and pyrene fluorescence of a phosphatidylcholine probe. Gangliosides had a dual effect. Below 1 mol % ganglioside the hexagonal II phase transition was affected but still occurred at lower temperature than in the absence of gangliosides. The presence of between 1 and 2 mol % gangliosides increased the temperature for formation of the hexagonal II phase and progressively decreased its cooperativity. Above 3 mol % gangliosides totally inhibited the formation of both the temperature-induced and composition-induced hexagonal phase, probably by opposing the geometric distortions necessary for the inverted micellar structures. Topics: Diglycerides; Gangliosides; Lipid Bilayers; Magnetic Resonance Spectroscopy; Micelles; Phosphatidylcholines; Phosphatidylethanolamines; Phosphorus; Thermodynamics	1994

Article

Year

Modulation by gangliosides of the lamellar-inverted micelle (hexagonal II) phase transition in mixtures containing phosphatidylethanolamine and dioleoylglycerol.

Proceedings of the National Academy of Sciences of the United States of America, 1994, Oct-11, Volume: 91, Issue:21

We studied the effect of gangliosides GD1a and GM1 on the lamellar-to-hexagonal II phase transition of mixtures of dioleoylphosphatidylethanolamine/dioleoylphosphatidyl choline, 3:1, and of transphosphatidylated phosphatidylethanolamine with dioleoylglycerol by high-sensitivity differential scanning calorimetry, 31P-NMR, and pyrene fluorescence of a phosphatidylcholine probe. Gangliosides had a dual effect. Below 1 mol % ganglioside the hexagonal II phase transition was affected but still occurred at lower temperature than in the absence of gangliosides. The presence of between 1 and 2 mol % gangliosides increased the temperature for formation of the hexagonal II phase and progressively decreased its cooperativity. Above 3 mol % gangliosides totally inhibited the formation of both the temperature-induced and composition-induced hexagonal phase, probably by opposing the geometric distortions necessary for the inverted micellar structures.

Topics: Diglycerides; Gangliosides; Lipid Bilayers; Magnetic Resonance Spectroscopy; Micelles; Phosphatidylcholines; Phosphatidylethanolamines; Phosphorus; Thermodynamics

1994