gamma-tert-butyl methotrexate has been researched along with methotrexate in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bader, H; Cucchi, CA; Freisheim, JH; Kohler, W; Moran, RG; Rosowsky, A | 1 |
| Bader, H; Cucchi, CA; Forsch, RA; Frei, E; Freisheim, JH; Rosowsky, A; Susten, SS | 1 |
| Forsch, R; Rosowsky, A; Uren, J; Wick, M | 1 |
| Cucchi, CA; Flatow, J; Frei, E; Rosowsky, A; Trites, D; Waxman, DJ; Wright, JE | 1 |
| Cucchi, CA; Flatow, J; Frei, E; Rosowsky, A; Wright, JE | 1 |
5 other study(ies) available for gamma-tert-butyl methotrexate and methotrexate
| Article | Year |
|---|---|
Methotrexate analogues. 33. N delta-acyl-N alpha-(4-amino-4-deoxypteroyl)-L-ornithine derivatives: synthesis and in vitro antitumor activity.
Topics: Aminopterin; Animals; Cell Division; Chemical Phenomena; Chemistry; Drug Resistance; Folic Acid Antagonists; Humans; Leukemia L1210; Methotrexate; Mice; Neoplasms, Experimental; Ornithine; Peptide Synthases; Pterins; Structure-Activity Relationship; Tumor Cells, Cultured | 1988 |
Methotrexate analogues. 25. Chemical and biological studies on the gamma-tert-butyl esters of methotrexate and aminopterin.
Topics: Aminopterin; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Drug Resistance; Esterification; Folic Acid Antagonists; Humans; In Vitro Techniques; Leukemia; Leukemia L1210; Methotrexate; Mice; T-Lymphocytes | 1985 |
Methotrexate analogues. 14. Synthesis of new gamma-substituted derivatives as dihydrofolate reductase inhibitors and potential anticancer agents.
Topics: Animals; Antineoplastic Agents; Folic Acid Antagonists; In Vitro Techniques; Lacticaseibacillus casei; Leukemia L1210; Methotrexate; Mice | 1981 |
Metabolism of methotrexate and gamma-tert-butyl methotrexate by human leukemic cells in culture and by hepatic aldehyde oxidase in vitro.
Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Cell Line; Chromatography, High Pressure Liquid; Humans; Kinetics; Leukemia, Lymphoid; Liver; Male; Methotrexate; Polyglutamic Acid; Rabbits; T-Lymphocytes | 1987 |
Methotrexate and gamma-tert-butyl methotrexate transport in CEM and CEM/MTX human leukemic lymphoblasts.
Topics: Cell Line; Drug Resistance; Humans; Kinetics; Leukemia, Lymphoid; Methotrexate; Tetrahydrofolate Dehydrogenase; Trimetrexate | 1993 |