gamma-sitosterol and corosolic-acid

Phytochemical investigation of the chemical constituents of the aerial parts of Scabiosa prolifera L. led to the isolation of one new flavonol glycoside, kaempferol-3-O-(4″,6″-di-E-p-coumaroyl)-β-D-galactopyranoside (1), along with ten other known compounds including luteolin-7-O-(2″-O-ethyl-β-glucopyranoside), β-sitosterol, β-sitosterylglucoside, ursolic acid, corosolic acid, ursolic acid 3-O-β-D-arabinopyranoside, apigenin, methyl-α-D-glucopyranoside, luteolin-7-O-β-glucopyranoside and isoorientin. The structures of all isolated compounds were established using chemical methods and spectroscopic methods including IR, UV, NMR (1D and 2D) and HRESIMS. All compounds were isolated for the first time from the plant. The antioxidant and cytotoxic activities of compounds 1 and 2 were also investigated.

Topics: Antioxidants; Cardiac Glycosides; Cytotoxins; Dipsacaceae; Flavonols; Glycosides; Kaempferols; Molecular Structure; Plant Components, Aerial; Plant Extracts; Sitosterols; Triterpenes

To study the chemical constituents of Rubus stans.. The chemical constituents were isolated and purified by silica gel and Sephadex LH-20 column chromatography. The structures were identified on the basis of spectroscopic analysis and physicochemical properties.. Eleven compounds were isolated and purified from the ethanol extract of Rubus stans. They were identified as β-sitosterol( 1),betulinic acid( 2),euscaphic acid( 3),ursolic acid( 4),corosolic acid( 5),kaempferol( 6),quercetin( 7),2α,3β,19α,23-tetrahydroxy-urs-12-en-28-oic acid( 8),β-daucosterol( 9),quercetin-3-O-β-D-glucoside( 10) and kaempferol-3-O-β-D-6-O-( p-hydroxycinnamoyl)-glucopyranoside( 11).. All the compounds are isolated from this plant for the first time.

Topics: Betulinic Acid; Kaempferols; Pentacyclic Triterpenes; Rubus; Sitosterols; Triterpenes; Ursolic Acid

To study the chemical constituents of Exochorda racemosa.. Compounds were isolated and purified by silica gel, Sephadex LH-20, MCI gel and RP-18 column chromatography, and their structures were determined by spectroscopic analysis.. Twenty compounds were isolated and identified as N-p-coumaroyl-N'-caffeoylputrescine (1), sutherlandin trans-p-coumarate (2), apigenin 7-O-methylglucuronide (3), astragalin (4), nicotiflorin (5), kaempferol 3-neohesperidoside (6), rutin (7), apigenin (8), luteolin (9), linalool-1-oic acid (10), betulalbuside A (11), ursolic acid (12) , corosolic acid (13), gynuramide II (14), beta-sitosterol (15), daucosterol (16), uridine (17), adenosine (18), syringin (19), and trans4-hydroxycinnamic acid (20), respectively.. All compounds were obtained from this plant for the first time, moreover, 1 was reported as a new natural product, and 2 is a naturally rare cyanogenic glycoside.

Topics: Apigenin; Flavonoids; Glucosides; Glucuronides; Kaempferols; Luteolin; Magnetic Resonance Spectroscopy; Phenols; Phenylpropionates; Rosaceae; Sitosterols; Triterpenes; Ursolic Acid

To investigate the chemical constituents of root of Rubus biflorus.. Isolation and purification were carried out by silica gel column chromatography and recrystallization and so on. Structural determination of the pure compounds was based on physico-chemical properties and various spectral data analysis (1H-NMR, 13C-NMR, IR, EI-MS).. Five compounds were isolated and identified as follows: lupeol acetate (I), corosolic acid (II), oleanic acid (III), 2alpha-hydroxyoleanolic acid (IV), sitosterol (V).. All these compounds are isolated from this plant for the first time.

Topics: Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Plant Roots; Plants, Medicinal; Rosaceae; Sitosterols; Steroids; Triterpenes