gamma-glutamyl dopa has been researched along with levodopa in 14 studies
| Studies (gamma-glutamyl dopa) | Trials (gamma-glutamyl dopa) | Recent Studies (post-2010) (gamma-glutamyl dopa) | Studies (levodopa) | Trials (levodopa) | Recent Studies (post-2010) (levodopa) |
|---|---|---|---|---|---|
| 43 | 6 | 2 | 17,774 | 1,900 | 4,946 |
| Protein | Taxonomy | gamma-glutamyl dopa (IC50) | levodopa (IC50) |
|---|---|---|---|
| integrase, partial | Human immunodeficiency virus 1 | 0.5939 | |
| lens epithelium-derived growth factor p75 | Homo sapiens (human) | 0.5939 | |
| Epidermal growth factor receptor | Homo sapiens (human) | 2.88 | |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | 3.729 | |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 2.146 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 2.258 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 10 (71.43) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barber, HE; Boateng, YA; Lee, MR; MacDonald, TM; Petrie, JC | 1 |
| Cummings, J; Matheson, LM; Maurice, L; Smyth, JF | 1 |
| Barthelmebs, M; Ehrhardt, JD; Grima, M; Imbs, JL; Vailly, B; Velly, J | 1 |
| Cummings, J; Matheson, LM; Smyth, JF | 1 |
| Casagrande, C; Ferrini, R; Merlo, L; Miragoli, G; Semeraro, C | 1 |
| Ichinose, H; Kumagai, H; Nagatsu, T; Suzuki, H; Togari, A | 1 |
| Lee, MR | 1 |
| McGrath, BP; Secombe, J; Shimizu, K; Wang, ZQ; Way, D | 2 |
| Drieman, JC; Smits, JF; Struijker Boudier, HA; Thijssen, HH; van Essen, H; van Kan, FJ | 1 |
| Pestana, M; Soares-da-Silva, P | 1 |
| Freestone, S; Johnston, NR; Lee, MR; Li Kam Wa, TC; Samson, RR | 1 |
| Bolliger, C; de Toledo, FG; Dousa, TP; Thompson, MA; Tyce, GM | 1 |
| Berndt, TJ; Knox, FG; Nath, KA; Sadiq, S | 1 |
2 review(s) available for gamma-glutamyl dopa and levodopa
| Article | Year |
|---|---|
Cardiovascular and renal action of dopaminergic prodrugs.
Topics: Animals; Cardiotonic Agents; Cats; Chemical Phenomena; Chemistry; Deoxyepinephrine; Dihydroxyphenylalanine; Dogs; Dopamine; Dopamine Agents; Drug Design; Female; Heart Failure; Hemodynamics; Humans; Kidney; Levodopa; Male; Prodrugs; Rabbits; Rats; Vasodilator Agents | 1989 |
Dopamine and the kidney.
Topics: Animals; Dihydroxyphenylalanine; Dogs; Dopamine; Edema; Female; Glutamates; Humans; Hypertension; Kidney; Kidney Failure, Chronic; Levodopa; Rats; Receptors, Dopamine; Renin-Angiotensin System; Sodium Chloride | 1982 |
1 trial(s) available for gamma-glutamyl dopa and levodopa
| Article | Year |
|---|---|
Renal metabolism and effects of the glutamyl derivatives of L-dopa and 5-hydroxytryptophan in man.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Adult; Cross-Over Studies; Dihydroxyphenylalanine; Dipeptides; Dopamine; Humans; Hydroxyindoleacetic Acid; Kidney; Levodopa; Male; Serotonin; Single-Blind Method; Sodium | 1996 |
11 other study(ies) available for gamma-glutamyl dopa and levodopa
| Article | Year |
|---|---|
Disposition of gamma-glutamyl levodopa (gludopa) after intravenous bolus injection in healthy volunteers.
Topics: Adult; Dihydroxyphenylalanine; Dopamine; Humans; Injections, Intravenous; Levodopa; Male; Metabolic Clearance Rate | 1991 |
Pharmacokinetics, bioavailability, metabolism, tissue distribution and urinary excretion of gamma-L-glutamyl-L-dopa in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biological Availability; Dihydroxyphenylalanine; Dopamine; Female; Humans; Kidney; Levodopa; Liver; Middle Aged; Rats; Rats, Inbred Strains; Tissue Distribution | 1990 |
Renal dopamine synthesis from precursors.
Topics: Animals; Dihydroxyphenylalanine; Dopamine; In Vitro Techniques; Kidney; Levodopa; Male; Perfusion; Prodrugs; Rats; Rats, Inbred Strains | 1990 |
Method for the determination of gamma-L-glutamyl-L-dihydroxyphenylalanine and its major metabolites L-dihydroxyphenylalanine, dopamine and 3,4-dihydroxyphenylacetic acid by high-performance liquid chromatography with electrochemical detection.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Humans; Kidney; Levodopa; Liver; Phenylacetates; Rats | 1990 |
Increase of catecholamines in mouse brain by systemic administration of gamma-glutamyl L-3,4-dihydroxyphenylalanine.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Brain; Catecholamines; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Levodopa; Mice; Norepinephrine; Time Factors | 1987 |
Sympatho-inhibitory effects of r-l-glutamyl-l-dopa in conscious rabbits.
Topics: Animals; Dihydroxyphenylalanine; Dopamine; Heart Rate; Kidney; Levodopa; Male; Norepinephrine; Prodrugs; Rabbits | 1994 |
Regional haemodynamic effects of dopamine and its prodrugs L-dopa and gludopa in the rat and in the glycerol-treated rat as a model for acute renal failure.
Topics: Acute Kidney Injury; Animals; Dihydroxyphenylalanine; Dopamine; Glycerol; Hemodynamics; Kidney; Levodopa; Male; Rats; Rats, Wistar; Renal Circulation | 1994 |
The renal handling of dopamine originating from L-dopa and gamma-glutamyl-L-dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Electrochemistry; In Vitro Techniques; Kidney; Levodopa; Male; Rats; Rats, Wistar | 1994 |
The dopamine prodrug, gludopa, decreases both renal and extrarenal noradrenaline spillover in conscious rabbits.
Topics: Animals; Blood Pressure; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Heart Rate; Kidney; Levodopa; Male; Norepinephrine; Rabbits | 1993 |
gamma-L-glutamyl-L-DOPA inhibits Na(+)-phosphate cotransport across renal brush border membranes and increases renal excretion of phosphate.
Topics: Alanine; Animals; Biological Transport; Calcium; Carrier Proteins; Cyclic AMP; Cyclic GMP; Dihydroxyphenylalanine; Dopamine; gamma-Glutamyltransferase; Kidney Tubules, Proximal; Levodopa; Male; Microvilli; Norepinephrine; Parathyroidectomy; Phosphates; Potassium; Proline; Rats; Sodium; Sodium-Phosphate Cotransporter Proteins; Symporters; Tritium | 1999 |
Effect of gamma-L-glutamyl-L-dopa on phosphate excretion.
Topics: Animals; Benzazepines; Blood Pressure; Dihydroxyphenylalanine; Dipeptides; Dopamine Antagonists; Glomerular Filtration Rate; Injections, Intravenous; Kidney; Levodopa; Male; Phosphates; Rats; Rats, Sprague-Dawley | 2000 |