Page last updated: 2024-09-03

gamma-glutamyl dopa and dihydroxyphenylalanine

gamma-glutamyl dopa has been researched along with dihydroxyphenylalanine in 42 studies

Compound Research Comparison

Studies (gamma-glutamyl dopa)	Trials (gamma-glutamyl dopa)	Recent Studies (post-2010) (gamma-glutamyl dopa)	Studies (dihydroxyphenylalanine)	Trials (dihydroxyphenylalanine)	Recent Studies (post-2010) (dihydroxyphenylalanine)
43	6	2	8,823	322	833

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (35.71)	18.7374
1990's	23 (54.76)	18.2507
2000's	2 (4.76)	29.6817
2010's	2 (4.76)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
McGrath, BP; Trigg, L; Wang, ZQ; Way, D	1
Barber, HE; Boateng, YA; Lee, MR; MacDonald, TM; Petrie, JC	1
Barthelmebs, M; Caillette, A; Ehrhardt, JD; Imbs, JL; Velly, J	1
Cummings, J; Matheson, LM; Maurice, L; Smyth, JF	1
Dupont, AG; Schoors, DF	1
Girbes, AR; Meijer, S; Reitsma, WD; Smit, AJ	1
Ellis, R; Freestone, S; Lee, MR; MacDonald, TM	1
Barthelmebs, M; Ehrhardt, JD; Grima, M; Imbs, JL; Vailly, B; Velly, J	1
Cummings, J; Matheson, LM; Smyth, JF	1
Barber, HE; Boateng, YA; Lee, MR; MacDonald, TM; Petrie, JC; Whiting, PH	1
Lee, MR	3
Casagrande, C; Ferrini, R; Merlo, L; Miragoli, G; Semeraro, C	1
Jeffrey, RF; Lee, MR; MacDonald, TM	2
Brown, J; Jeffrey, RF; Lee, MR; Macdonald, TM; Rae, PW	1
Brown, J; Harvey, JN; Lee, MR; Worth, DP	2
Brown, J; Harvey, JN; Lee, MR; Worral, A; Worth, DP	1
Ichinose, H; Kumagai, H; Nagatsu, T; Suzuki, H; Togari, A	1
Jeffrey, RF; Lee, MR; MacDonald, TM; Marwick, K	1
Freestone, S; Jeffrey, RF; Lee, MR; MacDonald, TM	1
Caillette, A; Ehrhardt, JD; Imbs, JL; Schmidt, M	1
Casson, IF; Clayden, DA; Cope, GF; Lee, MR	1
Anderson, CK; Casson, IF; Cope, GF; Lee, MR	1
McGrath, BP; Secombe, J; Shimizu, K; Wang, ZQ; Way, D	4
Fong, F; McGrath, BP; Shimizu, K; Trigg, L; Wang, ZQ; Way, D	1
Drieman, JC; Smits, JF; Struijker Boudier, HA; Thijssen, HH; van Essen, H; van Kan, FJ	1
Pestana, M; Soares-da-Silva, P	1
Freestone, S; Johnston, NR; Lee, MR; Li Kam Wa, TC; Samson, RR	1
Carey, RM; Felder, RA; Siragy, HM; Wang, ZQ	2
Aperia, A; Chen, S; Eklöf, AC; Holtbäck, U; Sundelöf, M	1
Bolliger, C; de Toledo, FG; Dousa, TP; Thompson, MA; Tyce, GM	1
Berndt, TJ; Knox, FG; Nath, KA; Sadiq, S	1
Berndt, TJ; Knox, FG; Liang, M; Tyce, GM	1
Di Sole, F; Hu, MC; McLeroy, P; Moe, OW; Zhang, J	1
Capdevila, JH; Gewin, L; Harris, RC; Wang, Y; Wei, S; Yao, B; Zhang, MZ	1

Reviews

4 review(s) available for gamma-glutamyl dopa and dihydroxyphenylalanine

Article	Year
Five years' experience with gamma-L-glutamyl-L-dopa: a relatively renally specific dopaminergic prodrug in man. Journal of autonomic pharmacology, 1990, Volume: 10 Suppl 1 Topics: Biological Availability; Blood Pressure; Dihydroxyphenylalanine; Humans; Kidney; Natriuresis; Prodrugs; Receptors, Dopamine	1990
Cardiovascular and renal action of dopaminergic prodrugs. Journal of cardiovascular pharmacology, 1989, Volume: 14 Suppl 8 Topics: Animals; Cardiotonic Agents; Cats; Chemical Phenomena; Chemistry; Deoxyepinephrine; Dihydroxyphenylalanine; Dogs; Dopamine; Dopamine Agents; Drug Design; Female; Heart Failure; Hemodynamics; Humans; Kidney; Levodopa; Male; Prodrugs; Rabbits; Rats; Vasodilator Agents	1989
Dopamine, the kidney and essential hypertension studies with gludopa. Clinical and experimental hypertension. Part A, Theory and practice, 1987, Volume: 9, Issue:5-6 Topics: Dihydroxyphenylalanine; Dopamine; Humans; Hypertension; Kidney	1987
Dopamine and the kidney. Clinical science (London, England : 1979), 1982, Volume: 62, Issue:5 Topics: Animals; Dihydroxyphenylalanine; Dogs; Dopamine; Edema; Female; Glutamates; Humans; Hypertension; Kidney; Kidney Failure, Chronic; Levodopa; Rats; Receptors, Dopamine; Renin-Angiotensin System; Sodium Chloride	1982

Trials

6 trial(s) available for gamma-glutamyl dopa and dihydroxyphenylalanine

Article	Year
Lithium and the renal response to gludopa, fenoldopam and dopamine. British journal of clinical pharmacology, 1990, Volume: 30, Issue:4 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Blood Pressure; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Drug Interactions; Fenoldopam; Humans; Kidney Tubules, Proximal; Lithium; Natriuresis; Receptors, Dopamine	1990
Effect of prolonged intravenous infusion of gludopa in humans and a preliminary study of its oral bioavailability. American journal of hypertension, 1990, Volume: 3, Issue:6 Pt 2 Topics: Absorption; Administration, Oral; Adult; Biological Availability; Blood Pressure; Dihydroxyphenylalanine; Dopamine; Female; Humans; Infusions, Intravenous; Male; Time Factors; Urine	1990
The renal and haemodynamic effects of a 10 h infusion of glutamyl-L-dopa in normal man. British journal of clinical pharmacology, 1989, Volume: 27, Issue:6 Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Dihydroxyphenylalanine; Dopamine; Electrolytes; Heart Rate; Hemodynamics; Humans; Infusions, Intravenous; Kallikreins; Kidney; Male; Potassium; Renin; Sodium	1989
A comparison of the renal actions of gamma-L-glutamyl-L-dopa and gamma-L-glutamyl-L-tyrosine in normal man. Clinical science (London, England : 1979), 1988, Volume: 74, Issue:1 Topics: Adult; Dihydroxyphenylalanine; Dipeptides; Dopamine; Humans; Kidney; Pharmaceutical Preparations; Prodrugs; Renin; Sodium	1988
gamma-L-Glutamyl-L-dopa is a dopamine pro-drug, relatively specific for the kidney in normal subjects. Clinical science (London, England : 1979), 1985, Volume: 69, Issue:2 Topics: Adult; Blood Pressure; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Heart Rate; Humans; Kidney; Male; Renal Circulation; Renin; Sodium Chloride	1985
Renal metabolism and effects of the glutamyl derivatives of L-dopa and 5-hydroxytryptophan in man. Clinical science (London, England : 1979), 1996, Volume: 91, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Adult; Cross-Over Studies; Dihydroxyphenylalanine; Dipeptides; Dopamine; Humans; Hydroxyindoleacetic Acid; Kidney; Levodopa; Male; Serotonin; Single-Blind Method; Sodium	1996

Other Studies

32 other study(ies) available for gamma-glutamyl dopa and dihydroxyphenylalanine

Article	Year
DA-1 receptors mediate renal effects of the dopamine prodrug, gludopa, in conscious rabbits. Clinical and experimental pharmacology & physiology, 1992, Volume: 19, Issue:5 Topics: Animals; Benzazepines; Blood Pressure; Consciousness; Dihydroxyphenylalanine; Dopamine Antagonists; Heart Rate; Hindlimb; Kidney; Male; Natriuresis; Prodrugs; Rabbits; Receptors, Dopamine; Renal Circulation; Urodynamics; Vascular Resistance	1992
Disposition of gamma-glutamyl levodopa (gludopa) after intravenous bolus injection in healthy volunteers. British journal of clinical pharmacology, 1991, Volume: 31, Issue:4 Topics: Adult; Dihydroxyphenylalanine; Dopamine; Humans; Injections, Intravenous; Levodopa; Male; Metabolic Clearance Rate	1991
Metabolism and vascular effects of gamma-L-glutamyl-L-dopa on the isolated rat kidney. Kidney international, 1990, Volume: 37, Issue:6 Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Dihydroxyphenylalanine; gamma-Glutamyltransferase; Kidney; Kidney Glomerulus; Male; Perfusion; Prodrugs; Rats; Rats, Inbred Strains; Receptors, Dopamine; Renal Circulation; Vasodilation	1990
Pharmacokinetics, bioavailability, metabolism, tissue distribution and urinary excretion of gamma-L-glutamyl-L-dopa in the rat. The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biological Availability; Dihydroxyphenylalanine; Dopamine; Female; Humans; Kidney; Levodopa; Liver; Middle Aged; Rats; Rats, Inbred Strains; Tissue Distribution	1990
Lithium and the natriuretic response to gludopa, fenoldopam and dopamine. British journal of clinical pharmacology, 1990, Volume: 30, Issue:4 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Blood Pressure; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Drug Interactions; Fenoldopam; Humans; Kidney Tubules, Proximal; Lithium; Natriuresis; Receptors, Dopamine	1990
Renal dopamine synthesis from precursors. American journal of hypertension, 1990, Volume: 3, Issue:6 Pt 2 Topics: Animals; Dihydroxyphenylalanine; Dopamine; In Vitro Techniques; Kidney; Levodopa; Male; Perfusion; Prodrugs; Rats; Rats, Inbred Strains	1990
Method for the determination of gamma-L-glutamyl-L-dihydroxyphenylalanine and its major metabolites L-dihydroxyphenylalanine, dopamine and 3,4-dihydroxyphenylacetic acid by high-performance liquid chromatography with electrochemical detection. Journal of chromatography, 1990, Jun-08, Volume: 528, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Humans; Kidney; Levodopa; Liver; Phenylacetates; Rats	1990
The pharmacokinetics of gamma-glutamyl-L-dopa in normal and anephric rats and rats with glycerol-induced acute renal failure. British journal of pharmacology, 1990, Volume: 101, Issue:2 Topics: Acute Kidney Injury; Animals; Dihydroxyphenylalanine; Glycerol; Kidney Diseases; Male; Nephrectomy; Rats; Rats, Inbred Strains	1990
The effect of lithium on the renal response to the dopamine prodrug gludopa in normal man. British journal of clinical pharmacology, 1988, Volume: 25, Issue:6 Topics: Adult; Atrial Natriuretic Factor; Cyclic AMP; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Hemodynamics; Humans; Kidney; Lithium; Male; Middle Aged; Prodrugs; Renin; Sodium	1988
Patients with essential hypertension have an exaggerated natriuretic response to the dopamine pro-drug glutamyl-dopa. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1985, Volume: 3, Issue:3 Topics: Adult; Dihydroxyphenylalanine; Female; Humans; Hypertension; Male; Middle Aged; Natriuresis; Prodrugs	1985
Domperidone treatment in man inhibits the fall in plasma renin activity induced by intravenous gamma-L-glutamyl-L-dopa. British journal of clinical pharmacology, 1986, Volume: 21, Issue:5 Topics: Adult; Dihydroxyphenylalanine; Domperidone; Humans; Injections, Intravenous; Kidney; Male; Potassium; Receptors, Dopamine; Renin; Sodium	1986
Increase of catecholamines in mouse brain by systemic administration of gamma-glutamyl L-3,4-dihydroxyphenylalanine. Journal of neurochemistry, 1987, Volume: 49, Issue:3 Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Brain; Catecholamines; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Levodopa; Mice; Norepinephrine; Time Factors	1987
The effect of carbidopa and indomethacin on the renal response to gamma-L-glutamyl-L-dopa in normal man. British journal of clinical pharmacology, 1988, Volume: 25, Issue:2 Topics: Adult; Carbidopa; Dihydroxyphenylalanine; Dopamine; Humans; Indomethacin; Kallikreins; Kidney; Male; Renin; Sodium	1988
(+)-sulpiride antagonises the renal effects of gamma-L-glutamyl-L-dopa in man. British journal of clinical pharmacology, 1988, Volume: 25, Issue:2 Topics: Adult; Dihydroxyphenylalanine; Glomerular Filtration Rate; Hemodynamics; Humans; Kidney; Male; Natriuresis; Receptors, Dopamine; Renin; Sulpiride	1988
[Metabolism and vascular effects of gammaglutamyl L-dopa on the isolated kidney of the rat]. Archives des maladies du coeur et des vaisseaux, 1988, Volume: 81 Spec No Topics: Animals; Dihydroxyphenylalanine; Dopamine; Kidney; Male; Perfusion; Rats; Rats, Inbred Strains; Vasodilation	1988
The protective effect of gamma-glutamyl L-dopa on the glycerol treated rat model of acute renal failure. Clinical science (London, England : 1979), 1983, Volume: 65, Issue:2 Topics: Acute Kidney Injury; Animals; Creatinine; Dihydroxyphenylalanine; Dopamine; Glycerol; Male; Rats; Rats, Inbred Strains; Sodium	1983
The effect of dietary sodium chloride and gamma-glutamyl dopa on tubular necrosis following glycerol administration in the rat. British journal of experimental pathology, 1982, Volume: 63, Issue:4 Topics: Acute Kidney Injury; Administration, Oral; Animals; Dihydroxyphenylalanine; Glycerol; Kidney; Kidney Tubular Necrosis, Acute; Male; Rats; Rats, Inbred Strains; Sodium Chloride	1982
Sympatho-inhibitory effects of gamma-l-glutamyl-l-dopa are not mediated by activation of dopamine-2 receptors in conscious rabbits. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:3 Topics: Animals; Benzamides; Blood-Brain Barrier; Brain; Dihydroxyphenylalanine; Dopamine Antagonists; Infusions, Intravenous; Male; Norepinephrine; Rabbits; Receptors, Dopamine D2	1995
Beneficial acute effects of selective modulation of renal dopamine system by gamma-L-glutamyl-L-dopa in rabbits with congestive heart failure. Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:6 Topics: Animals; Benzazepines; Blood Pressure; Dihydroxyphenylalanine; Dopamine; Doxorubicin; Heart Failure; Heart Rate; Hemodynamics; Hindlimb; Male; Rabbits; Renal Circulation; Renin; Sodium; Ultrasonography; Vascular Resistance	1993
Sympatho-inhibitory effects of r-l-glutamyl-l-dopa in conscious rabbits. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1994, Volume: 15, Issue:1 Topics: Animals; Dihydroxyphenylalanine; Dopamine; Heart Rate; Kidney; Levodopa; Male; Norepinephrine; Prodrugs; Rabbits	1994
Regional haemodynamic effects of dopamine and its prodrugs L-dopa and gludopa in the rat and in the glycerol-treated rat as a model for acute renal failure. British journal of pharmacology, 1994, Volume: 111, Issue:4 Topics: Acute Kidney Injury; Animals; Dihydroxyphenylalanine; Dopamine; Glycerol; Hemodynamics; Kidney; Levodopa; Male; Rats; Rats, Wistar; Renal Circulation	1994
The renal handling of dopamine originating from L-dopa and gamma-glutamyl-L-dopa. British journal of pharmacology, 1994, Volume: 112, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Electrochemistry; In Vitro Techniques; Kidney; Levodopa; Male; Rats; Rats, Wistar	1994
The dopamine prodrug, gludopa, decreases both renal and extrarenal noradrenaline spillover in conscious rabbits. Clinical and experimental pharmacology & physiology, 1993, Volume: 20, Issue:5 Topics: Animals; Blood Pressure; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Heart Rate; Kidney; Levodopa; Male; Norepinephrine; Rabbits	1993
Suppression of noradrenaline spillover by the dopamine prodrug gamma-L-glutamyl-L-dopa: a central effect? Hypertension research : official journal of the Japanese Society of Hypertension, 1995, Volume: 18 Suppl 1 Topics: Animals; Benzamides; Brain Chemistry; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Hemodynamics; Kidney; Kinetics; Male; Norepinephrine; p-Aminohippuric Acid; Prodrugs; Rabbits; Receptors, Dopamine D2	1995
Intrarenal dopamine production and distribution in the rat. Physiological control of sodium excretion. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:1 Pt 2 Topics: Animals; Dihydroxyphenylalanine; Dopamine; Female; Kidney; Microdialysis; Prodrugs; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium; Sodium Chloride, Dietary	1997
Inhibition of COMT induces dopamine-dependent natriuresis and inhibition of proximal tubular Na+,K+-ATPase. Kidney international, 1997, Volume: 52, Issue:3 Topics: Animals; Benzazepines; Catechol O-Methyltransferase Inhibitors; Catechols; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Enzyme Inhibitors; Kidney Tubules, Proximal; Male; Natriuresis; Pentanones; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase	1997
Renal dopamine production and release in the rat: a microdialysis study. Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42 Topics: Angiotensin II; Animals; Dihydroxyphenylalanine; Diuresis; Dopamine; Kidney; Microdialysis; Natriuresis; Rats; Renal Circulation; Sodium, Dietary	1998
gamma-L-glutamyl-L-DOPA inhibits Na(+)-phosphate cotransport across renal brush border membranes and increases renal excretion of phosphate. Kidney international, 1999, Volume: 55, Issue:5 Topics: Alanine; Animals; Biological Transport; Calcium; Carrier Proteins; Cyclic AMP; Cyclic GMP; Dihydroxyphenylalanine; Dopamine; gamma-Glutamyltransferase; Kidney Tubules, Proximal; Levodopa; Male; Microvilli; Norepinephrine; Parathyroidectomy; Phosphates; Potassium; Proline; Rats; Sodium; Sodium-Phosphate Cotransporter Proteins; Symporters; Tritium	1999
Effect of gamma-L-glutamyl-L-dopa on phosphate excretion. The Journal of laboratory and clinical medicine, 2000, Volume: 135, Issue:1 Topics: Animals; Benzazepines; Blood Pressure; Dihydroxyphenylalanine; Dipeptides; Dopamine Antagonists; Glomerular Filtration Rate; Injections, Intravenous; Kidney; Levodopa; Male; Phosphates; Rats; Rats, Sprague-Dawley	2000
Intrarenal serotonin, dopamine, and phosphate handling in remnant kidneys. Kidney international, 2001, Volume: 59, Issue:2 Topics: Animals; Dihydroxyphenylalanine; Dopamine; Kidney; Male; Methiothepin; Nephrectomy; Phosphates; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists	2001
Chronic regulation of the renal Na(+)/H(+) exchanger NHE3 by dopamine: translational and posttranslational mechanisms. American journal of physiology. Renal physiology, 2013, May-01, Volume: 304, Issue:9 Topics: Animals; Cell Line; Cells, Cultured; Dihydroxyphenylalanine; Dopamine; Dopamine Agents; Gene Expression Regulation; Half-Life; In Vitro Techniques; Kidney; Models, Animal; Opossums; Protein Biosynthesis; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Ubiquitination	2013
Role of epoxyeicosatrienoic acids (EETs) in mediation of dopamine's effects in the kidney. American journal of physiology. Renal physiology, 2013, Dec-15, Volume: 305, Issue:12 Topics: Animals; Arachidonic Acid; Aromatic-L-Amino-Acid Decarboxylases; Catechol O-Methyltransferase; Cells, Cultured; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Diet, Sodium-Restricted; Dihydroxyphenylalanine; Disease Models, Animal; Diuresis; Dopamine; Dopamine Agents; Hypertension; Kidney; Male; Mice; Mice, Knockout; Natriuresis; Sodium Chloride, Dietary	2013