gamma-cyclodextrin has been researched along with efavirenz* in 1 studies
1 other study(ies) available for gamma-cyclodextrin and efavirenz
| Article | Year |
|---|---|
Inclusion Compound of Efavirenz and γ-Cyclodextrin: Solid State Studies and Effect on Solubility.
Efavirenz is an antiretroviral drug of widespread use in the management of infections with human immunodeficiency virus type 1 (HIV-1). Efavirenz is also used in paediatrics, but due to its very poor aqueous solubility the liquid formulations available resort to oil-based excipients. In this report we describe the interaction of γ-cyclodextrin with efavirenz in solution and in the solid state. In aqueous solution, the preferential host-guest stoichiometry was determined by the continuous variation method using Topics: Alkynes; Benzoxazines; Chemistry, Pharmaceutical; Cyclopropanes; Freeze Drying; gamma-Cyclodextrins; Humans; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2021 |