gamma-carboline has been researched along with latrepirdine in 4 studies
| Studies (gamma-carboline) | Trials (gamma-carboline) | Recent Studies (post-2010) (gamma-carboline) | Studies (latrepirdine) | Trials (latrepirdine) | Recent Studies (post-2010) (latrepirdine) |
|---|---|---|---|---|---|
| 44 | 0 | 26 | 126 | 7 | 59 |
| Protein | Taxonomy | gamma-carboline (IC50) | latrepirdine (IC50) |
|---|---|---|---|
| Cholinesterase | Homo sapiens (human) | 7.9 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.8695 | |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 1.58 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.98 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 1.58 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 1.58 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 1.58 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 1.58 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 1.58 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 1.58 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frolov, EB; Ivachtchenko, AV; Khvat, AV; Kysil, VM; Mitkin, OD; Okun, IM; Tkachenko, SE | 1 |
| Dong, H; Driver, TG; Latka, RT | 1 |
| Aksinenko, A; Bachurin, S; Bahzenova, N; Fisenko, V; Grigoriev, V; Lesch, KP; Lillesaar, C; Markova, N; Redkozubova, O; Schmitt-Böhrer, AG; Serkova, T; Shevtsova, E; Sokolov, V; Strekalova, T; Trofimov, A; Umriukhin, A; Vinogradova, D; Zamoyski, V | 1 |
| Amaladass, P; Chidara, S; Damerla, VSB; Gupta, S; Karmakar, A; Mogili, P; Pasunooti, KK; Puli, VS; Voggu, R | 1 |
4 other study(ies) available for gamma-carboline and latrepirdine
| Article | Year |
|---|---|
Synthesis and biological evaluation of novel gamma-carboline analogues of Dimebon as potent 5-HT6 receptor antagonists.
Topics: Carbolines; Cell Line; Histamine H1 Antagonists; Humans; Indoles; Inhibitory Concentration 50; Receptors, Histamine H1; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship | 2009 |
Ruthenium-catalyzed γ-carbolinium ion formation from aryl azides; synthesis of dimebolin.
Topics: Azides; Carbolines; Catalysis; Combinatorial Chemistry Techniques; Indoles; Molecular Structure; Ruthenium | 2011 |
Pro-neurogenic, Memory-Enhancing and Anti-stress Effects of DF302, a Novel Fluorine Gamma-Carboline Derivative with Multi-target Mechanism of Action.
Topics: Animals; Carbolines; Drug Delivery Systems; Fluorine Compounds; Indoles; Male; Memory; Mice; Mice, Inbred C57BL; Neurogenesis; Rats; Receptors, Serotonin; Stress, Psychological | 2018 |
Design, Synthesis, Molecular Docking Study and Biological Evaluation of Novel γ-Carboline Derivatives of Latrepirdine (Dimebon) as Potent Anticancer Agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2023 |