gamma-aminobutyric acid and phenytoin

gamma-aminobutyric acid has been researched along with phenytoin in 185 studies

Research

Studies (185)

TimeframeStudies, this research(%)All Research%
pre-199071 (38.38)18.7374
1990's48 (25.95)18.2507
2000's36 (19.46)29.6817
2010's30 (16.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brahce, L; Gregor, VE; Lobbestael, SJ; Mayhugh, DR; Nugiel, D; Pavia, MR; Schwarz, RD; Taylor, CP; Vartanian, MG1
Andrews, PR; Craik, DJ; Martin, JL1
Bartholini, G; Desarmenien, M; Feltz, P; Headley, PM; Kaplan, JP; Lloyd, KG; Raizon, BM; Worms, P1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Berl, S; Nicklas, WJ; Weinberger, J1
Markovich, VV; Ostrovskaia, RU1
Kozhechkin, SN; Markovich, VV; Molodavkin, GM; Ostrovskaya, RU; Voronina, TA; Zakusov, VV1
Bruni, J; Wilder, BJ1
Costa, E; Guidotti, A; Mao, CC; Suria, A1
Nistico, G1
Kacz, D; Stach, R1
Feussner, GK; Lust, WD; McCandless, DW; Passonneau, JV1
Meldrum, BS1
Costa, E; Guidotti, A; Mao, CC1
Drucker-Colín, RR; Durán, L; Levi, G; Meza-Ruíz, G; Tapia, R1
Ngo, TT; Smith, JA; Tunnicliff, G1
Hansen, S; Kennedy, J; Perry, TL; Thompson, GB; Wada, JA1
Ayala, GF; Dichter, HN; Johnston, D; Lin, S1
Snider, RS; Snider, SR1
Gabra-Sanders, T; Hitchcock, E1
Anlezark, G; Balzamo, E; Horton, RW; Meldrum, BS; Trimble, M1
Barker, JL1
Ayala, GF; Raabe, W1
Cavalheiro, EA; Dziki, M; Kleinrok, Z; Parada, J; Turski, W1
Jackson, HC; Nutt, DJ1
Fredow, G; Löscher, W1
Fromm, GH; Kondo, T; Schmidt, B1
Higuchi, T; Kato, N; Minatogawa, Y; Nagaki, S1
Birnstiel, S; Haas, HL1
Macdonald, RL; McLean, MJ; Skerritt, JH1
Kater, SB; Mattson, MP1
Morselli, PL1
Theodore, WH1
Fukushima, Y; Hirano, T; Hishida, R; Kaneko, S; Kondo, T; Matsunaga, M; Otani, K1
Clayton, RM; Sedowofia, SK1
Macdonald, RL; McLean, MJ5
Teo, WL; Wong, PT1
Lloyd, KG1
Graves, NM; Holmes, GB; Leppik, IE1
Chadwick, D; Crawford, P1
Kantarev, N; Parisheva, Z; Toreva, D1
Lee, HS; Tan, SF; Wong, PT1
Bowman, T; Cloyd, J; Crosby, C; Dreifuss, FE; Graves, N; Jacobs, M; Leppik, IE; Porter, R; Santilli, N; Stackman, J1
Brundage, RC; Cloyd, JC; Graves, NM; Leppik, IE; Welty, TE1
Schmidt, D; Utech, K1
Rock, DM; Taylor, CP1
Brailowsky, S; Efron, R; Knight, RT1
Chweh, AY; Swinyard, EA; Wolf, HH1
Burke, JT; Thénot, JP1
Lux, HD1
Iversen, LL; Minchin, MC1
Lascelles, PT; Patsalos, PN1
Alphs, L; Davis, JM1
de Boer, T; Stoof, JC; van Duijn, H1
Axelrod, J; Gallager, DW; Hirata, F; Mallorga, P; Strittmatter, W; Tallman, JF; Thomas, JW1
Smythies, JR1
Nicoll, RA; Wojtowicz, JM1
Czuczwar, SJ; Kleinrok, Z; Kozicka, M1
Connors, BW1
Adams, PR; Banks, FW; Constanti, A2
Gallager, DW; Wakeman, EA1
Folbergrová, J1
Burnham, WM; Livingston, KE; Madras, BK; Okazaki, MM; Spero, L1
Imura, H; Kato, Y; Tatsuoka, Y; Yoshida, K1
Kulkarni, SK; Mehta, AK1
Battistin, L; Berlese, G; Roman, G; Varotto, M1
Fariello, RG; Golden, GT1
Chmielewska, B; Czuczwar, SJ; Kleinrok, Z; Turski, WA1
Hitchcock, E; Teixeira, M1
Neale, EA; Nelson, PG; Schrier, BK; Swaiman, KF1
Aickin, CC; Deisz, RA; Lux, HD2
Battistin, L; Roman, G; Varotto, M1
Buti, D; Cianchetti, C; Dalla Bernardina, B; Fontana, E; Fusco, L; Galeone, D; Gnanasakthy, A; Iudice, A; Torelli, D; Vigevano, F1
Becker, A; Grecksch, G; Ostner, C; Piönnigs, B1
Haas, KZ; Moshé, SL; Sperber, EF; Velísek, L; Velísková, J1
Tyndel, F1
Hekster, YA; Keyser, A; Lammers, MW; Meinardi, H; Renier, WO; van Lier, H; Wijsman, DJ1
Okamoto, Y; Ota, K1
Avanzini, G; Battino, D; Estienne, M1
Marsden, CA; Martin, KF; Rowley, HL1
Kelly, KM; Macdonald, RL1
Gram, L; Rogvi-Hansen, B1
George, B; Kulkarni, SK1
Fleisher, D; Kim, J; Stevenson, CM1
Brown-Croyts, LM; Ko, GY; Teyler, TJ1
Mercadé Cerdá, JM1
Chaushu, G; Givol, N; Katz, J; Shemer, J; Taicher, S1
Brunko, E; Caroyer, JM; Mavroudakis, N; Zegers de Beyl, D1
Chapman, DP; Giles, WH1
Vossler, DG; Wyler, AR1
De Feo, MR; Del Priore, D; Mecarelli, O1
Cheng, LL; Gean, PW; Tsai, JJ; Wang, SJ1
Curry, WJ; Kulling, DL1
Bazil, CW; Pedley, TA1
Boothe, DM1
Beck, H; Elger, CE; Schramm, J; Schumacher, TB; Steinhäuser, C1
Luer, MS; Winkler, SR1
Bruni, J2
Anderson, GD1
Hagan, RM; Higgins, GA; Kirkby, D; Southam, E1
Arroyo, S; Martínez, I; Ribalta, T; Rumiá, J1
Chang, KH; Cheon, JE; Han, MH; Jeong, SW; Kim, SS; Kim, ST; Lee, SK; Suh, DC1
Bernardi, G; Calabresi, P; Centonze, D; Marfia, GA; Pisani, A1
Tennison, M1
Hamer, HM; Morris, HH1
Bernstein, P; Faught, RE; Holmes, GL; Magnus-Miller, L; McLean, MJ; Morrell, MJ; Privitera, MD; Rose-Legatt, A; Willmore, LJ1
Allen, E; Reece, PA; Sedman, AJ; Tsanaclis, LM; Wroe, SJ1
Covey, DF; de la Cruz, MA; Hill, MW; Rothman, SM1
Brodie, MJ1
Fariello, RG; Maj, R; McArthur, RA; Pevarello, P; Salvati, P; Varasi, M1
Cunningham, MO; Dhillon, A; Jones, RS; Wood, SJ1
Brückner, C; Heinemann, U1
Carwile, ST; Husain, AM; Miller, PP; Radtke, RA1
Bac, P; Delcourt, P; Herrenknecht, C; Maurois, P; Stables, JP; Vamecq, J1
Ebert, U; Löscher, W; Reissmüller, E1
Al-Hassan, MI; Bawazir, SA; Matar, KM; Nicholls, PJ; Tekle, A1
Harden, CL1
Janowsky, DS1
Jagoda, A; Yoon, Y1
Cunningham, MO; Jones, RS1
Desiena, G; Lensu, S; Malmberg-Aiello, P; Tuomisto, L1
Covington, EC1
Backonja, MM1
Rekling, JC1
Bergin, AM; Connolly, M1
Annovazzi, PO; Colombo, B; Comi, G1
Jevtovic-Todorovic, V; Rastogi, AJ; Todorovic, SM1
BHARGAVA, KP; BHATTACHARYA, SS; KISHOR, K; SAXENA, PN1
Berlowitz, D; Charbonneau, A; Cramer, J; Kazis, L; Knoefel, J; Mandell, A; Pugh, MJ1
Feeney, L; Jacobs, B; McKeever, C; Reynolds, ER; Rojahn, E; Stauffer, EA1
Gau, CS; Lin, CJ; Liou, HH; Shyu, MK; Wu, SP1
Hevia, A; Hinchey, P; Hobgood, C1
Yatham, LN1
Papp, Z; Török, L1
Watson, CP1
Alvey, CW; Bockbrader, HN; Brodie, MJ; Bron, NJ; Gibson, GL; Hounslow, NJ; Posvar, EL; Randinitis, EJ; Wesche, DL; Wilson, EA1
Graeme Shaw, D; Hoang, BX; Hoang, C; Levine, SA; Pham, P1
Bröcker, EB; Pfeuffer, P; Raith, P; Seitz, CS; Trautmann, A1
Crofoot, K; Filtz, TM; Rodriguez-Proteau, R; von Borstel Smith, M1
Takahashi, Y1
Abend, NS; Bonnemann, CG; Licht, DJ1
Jones, RS; Wetterstrand, C; Yang, J1
Shetty, AJ1
Jimmy, B; Jose, J; Saravu, K; Shastry, BA1
Aykac, B; Bingol, CA; Karlikaya, G; Sayin, M; Türe, H; Türe, U1
Cano Ruiz, A; Cobo Ibañez, N; Crespo Pérez, L; Gobernado Serrano, JM; Milicua Salamero, JM; Moreira Vicente, V1
Gottschalk, A1
Alcantara-Gonzalez, D; Cuellar-Herrera, M; Neri-Bazan, L; Peña, F; Rocha, L1
Mula, M1
Ahmad, S; Akhtar, M; Basu, A; Basu, M; Dev, A; Jayaprakash, V; Mishra, N; Oraon, A; Pattnaik, AK; Swaroop, S; Tripapthi, SN1
Bogo, MR; Bonan, CD; Capiotti, KM; Cusinato, CT; Franco, TM; Piato, AL; Rico, EP; Siebel, AM1
Arif, H; Bazil, CW; Buchsbaum, R; Hirsch, LJ; Pierro, J; Resor, SR; Sims, J; Whalen, M1
Bostanci, N; Sarıkaya, R; Yüksel, M1
Lang, SY; Shi, XB; Tian, HJ; Wang, RF; Wang, XQ; Yang, F1
Feuerstein, TJ; Freiman, TM; Kammerer, M; Rassner, MP1
Luna-Munguia, H; Orozco-Suarez, S; Rocha, L1
Aldana, BI; Chiu, LM; Guarneros, A; Sanchez-Tafolla, BM; Sitges, M1
Heyward, PM; Igelström, KM; Shirley, CH1
Doreswamy, M; Gingrich, KJ; Kolls, BJ; Swisher, CB; Vredenburgh, JJ1
Ariyawardana, A; Pallegama, R; Ranasinghe, A; Sitheeque, M1
Baines, RA; Günay, C; Lin, WH; Marley, R; Prinz, AA1
Bogo, MR; Bonan, CD; Nery, LR; Piato, AL; Schaefer, IC; Siebel, AM1
Dambach, H; Faustmann, PM; Haase, CG; Hinkerohe, D; Hufnagel, A; Moinfar, Z; Prochnow, N; Stienen, MN1
Donevan, S; Galvin, S; Hain, H; Lotarski, S; Offord, J; Peterson, J; Strenkowski, B1
Deeb, S; Logan, BK; McKeown, DA; Scott, KS; Torrance, HJ; Wylie, FM1
Buchsbaum, R; Chen, B; Choi, H; Detyniecki, K; Hirsch, LJ; Javed, A; Kato, K; Legge, A; Moeller, J1
Cock, HR1
Baines, RA; Fan, YN; Masullo, L; Streit, AK1
Biegstraaten, M; Hollak, CE; Linthorst, GE; Schuller, Y; Van Schaik, IN1
Bártfai, G; Devosa, I; Szok, D; Vanya, M1
Bastin, ML; Cook, AM; Oyler, DR; Smetana, KS1
Hsieh, CY; Huang, CW; Lai, EC; Lin, SJ; Setoguchi, S; Su, CC; Yang, YK1
Beydemir, Ş; Demir, Y1
Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J2
Izumo, N; Kanda, J; Kobayashi, Y; Onodera, K; Shimakura, T; Takahashi, HE; Wakabayashi, H; Yamamoto, N1
Ishii, K; Miyake, Z; Tamaoka, A1

Reviews

37 review(s) available for gamma-aminobutyric acid and phenytoin

ArticleYear
Valproic acid. Review of a new antiepileptic drug.
    Archives of neurology, 1979, Volume: 36, Issue:7

    Topics: Adolescent; Adult; Animals; Brain Chemistry; Drug Interactions; Electric Stimulation; Electroencephalography; Epilepsies, Myoclonic; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; gamma-Aminobutyric Acid; Half-Life; Humans; Intestinal Absorption; Mice; Phenobarbital; Phenytoin; Seizures; Sleep Stages; Valproic Acid

1979
New concepts on the mechanism of action of benzodiazepines.
    Life sciences, 1975, Jul-15, Volume: 17, Issue:2

    Topics: Animals; Benzodiazepines; Cerebellum; Chlordiazepoxide; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Ganglia, Autonomic; Glycine; Humans; Isoniazid; Medulla Oblongata; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Receptors, Drug; Seizures; Sensory Receptor Cells; Spinal Cord; Strychnine; Substantia Nigra

1975
Anticonvulsant drugs: mechanisms of action.
    Advances in neurology, 1986, Volume: 44

    Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Biomechanical Phenomena; Carbamazepine; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents; Phenytoin; Primidone; Succinimides; Synapses; Synaptic Transmission; Valproic Acid

1986
[GABAergic theory of epilepsy].
    La Revue du praticien, 1986, Jan-21, Volume: 36, Issue:5

    Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Benzodiazepines; Bicuculline; Brain; Dogs; Epilepsy; gamma-Aminobutyric Acid; Humans; Mice; Nerve Endings; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Receptors, GABA-A; Synapses; Valproic Acid

1986
Determination of antiepileptic drugs.
    Journal of chromatography, 1985, May-10, Volume: 340

    Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, Gas; Chromatography, Liquid; Clonazepam; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Mephenytoin; Monitoring, Physiologic; Phenytoin; Primidone; Succinimides; Valproic Acid

1985
The development of epilepsy in the paediatric brain.
    Seizure, 1994, Volume: 3, Issue:4

    Topics: Age Factors; Animals; Baclofen; Child; Epilepsy; gamma-Aminobutyric Acid; Hippocampus; Humans; Infant, Newborn; Kainic Acid; Kindling, Neurologic; Phenytoin; Rats; Receptors, GABA-A; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate

1994
[Diagnosis and therapy of epilepsy and myoclonus].
    Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51, Issue:11

    Topics: Acetates; Amines; Cerebral Cortex; Cyclohexanecarboxylic Acids; Electrophysiology; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Myoclonus; Phenytoin

1993
Clinical pharmacokinetics of antiepileptic drugs in paediatric patients. Part II. Phenytoin, carbamazepine, sulthiame, lamotrigine, vigabatrin, oxcarbazepine and felbamate.
    Clinical pharmacokinetics, 1995, Volume: 29, Issue:5

    Topics: Adult; Anticonvulsants; Carbamazepine; Child; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenytoin; Thiazines; Triazines; Vigabatrin

1995
Antiepileptic drug mechanisms of action.
    Epilepsia, 1995, Volume: 36 Suppl 2

    Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Calcium Channels; Carbamazepine; Central Nervous System; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Phenytoin; Rats; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium Channels; Triazines; Trimethadione; Valproic Acid; Vigabatrin

1995
Adverse effects of established and new antiepileptic drugs: an attempted comparison.
    Pharmacology & therapeutics, 1995, Volume: 68, Issue:3

    Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Humans; Nervous System Diseases; Oxcarbazepine; Phenobarbital; Phenytoin; Sleep Stages; Vigabatrin

1995
[Antiepileptic drugs: mechanism of action].
    Neurologia (Barcelona, Spain), 1996, Volume: 11 Suppl 4

    Topics: Anticonvulsants; Barbiturates; Carbamazepine; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenytoin; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Triazines; Vigabatrin

1996
Pharmacologic and dietary therapies in epilepsy: conventional treatments and recent advances.
    Southern medical journal, 1997, Volume: 90, Issue:5

    Topics: Acetates; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketone Bodies; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Triazines; Valproic Acid; Vigabatrin

1997
Recent advancements in epilepsy.
    Surgical neurology, 1997, Volume: 48, Issue:2

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Neurosurgery; Phenylcarbamates; Phenytoin; Pia Mater; Propylene Glycols; Temporal Lobe; Topiramate; Triazines; Vigabatrin

1997
Newer antiepileptic drugs: gabapentin, lamotrigine, felbamate, topiramate and fosphenytoin.
    American family physician, 1998, Feb-01, Volume: 57, Issue:3

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines

1998
Advances in the medical treatment of epilepsy.
    Annual review of medicine, 1998, Volume: 49

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diazepam; Drug Approval; Drug Design; Drug Interactions; Drug Resistance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Ketones; Lamotrigine; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Phenylcarbamates; Phenytoin; Prodrugs; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Valproic Acid; Vigabatrin

1998
Anticonvulsant therapy in small animals.
    The Veterinary clinics of North America. Small animal practice, 1998, Volume: 28, Issue:2

    Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Clonazepam; Clorazepate Dipotassium; Cyclohexanecarboxylic Acids; Diazepam; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Mephenytoin; Pentobarbital; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Seizures; Valproic Acid

1998
Antiepileptic drug review: part 2.
    Surgical neurology, 1998, Volume: 49, Issue:5

    Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Cyclohexanecarboxylic Acids; Drug Interactions; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines

1998
A mechanistic approach to antiepileptic drug interactions.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:5

    Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin

1998
Monostars: an aid to choosing an antiepileptic drug as monotherapy.
    Epilepsia, 1999, Volume: 40 Suppl 6

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Practice Patterns, Physicians'; Triazines; Valproic Acid; Vigabatrin

1999
Therapeutic safety monitoring: what to look for and when to look for it.
    Epilepsia, 2000, Volume: 41 Suppl 8

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Topiramate; Triazines; Valproic Acid; Vigabatrin

2000
New treatments of bipolar disorder.
    Current psychiatry reports, 1999, Volume: 1, Issue:2

    Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Olanzapine; Phenytoin; Pirenzepine; Topiramate; Treatment Outcome; Triazines

1999
New antiepileptic drugs and preparations.
    Emergency medicine clinics of North America, 2000, Volume: 18, Issue:4

    Topics: Acetates; Administration, Rectal; Age Factors; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diazepam; Drug Overdose; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines; Valproic Acid

2000
Anticonvulsants for neuropathic pain and detoxification.
    Cleveland Clinic journal of medicine, 1998, Volume: 65 Suppl 1

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clonazepam; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Inactivation, Metabolic; Lamotrigine; Neuralgia; Phenytoin; Substance Withdrawal Syndrome; Triazines; Valproic Acid

1998
Use of anticonvulsants for treatment of neuropathic pain.
    Neurology, 2002, Sep-10, Volume: 59, Issue:5 Suppl 2

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nervous System Diseases; Pain; Phenytoin; Triazines; Zonisamide

2002
New antiepileptic drug therapies.
    Neurologic clinics, 2002, Volume: 20, Issue:4

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Phenytoin; Piracetam; Propylene Glycols; Thiazines; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2002
Neuropathic cranial pain.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2003, Volume: 24 Suppl 2

    Topics: Acetates; Amines; Analgesics; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Fructose; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Lamotrigine; Nervous System Diseases; Phenytoin; Topiramate; Triazines

2003
Newer anticonvulsants in the treatment of bipolar disorder.
    The Journal of clinical psychiatry, 2004, Volume: 65 Suppl 10

    Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Depressive Disorder; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide

2004
Management issues of neuropathic trigeminal pain from a medical perspective.
    Journal of orofacial pain, 2004,Fall, Volume: 18, Issue:4

    Topics: Amines; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents; Baclofen; Carbamazepine; Cranial Nerve Injuries; Cyclohexanecarboxylic Acids; Facial Neuralgia; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Lamotrigine; Narcotics; Phenytoin; Triazines; Trigeminal Nerve Injuries; Trigeminal Neuralgia

2004
[Neuromuscular disorders caused by adverse effects of antiepileptics].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2007, Aug-10, Volume: 96, Issue:8

    Topics: Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Neuromuscular Diseases; Phenobarbital; Phenytoin; Topiramate; Valproic Acid; Zonisamide

2007
[Anticonvulsant hypersensitivity syndrome: an entity to be remembered].
    Gastroenterologia y hepatologia, 2009, Volume: 32, Issue:10

    Topics: Adolescent; Amines; Anemia, Hemolytic; Anticonvulsants; Astrocytoma; Brain Neoplasms; Carbamazepine; Chemical and Drug Induced Liver Injury; Cyclohexanecarboxylic Acids; Diagnostic Errors; Drug Eruptions; Drug Therapy, Combination; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Female; Gabapentin; gamma-Aminobutyric Acid; Ganglioneuroma; Humans; Lymphatic Diseases; Parahippocampal Gyrus; Phenytoin; Radiosurgery

2009
New antiepileptic drugs: molecular targets.
    Central nervous system agents in medicinal chemistry, 2009, Volume: 9, Issue:2

    Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Carbamazepine; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Monitoring; Electroshock; Epilepsy; Ethosuximide; gamma-Aminobutyric Acid; Humans; Molecular Structure; Neurotransmitter Transport Proteins; Phenytoin; Randomized Controlled Trials as Topic; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship; Synaptic Transmission; Treatment Outcome; Valproic Acid

2009
Drug-induced status epilepticus.
    Epilepsy & behavior : E&B, 2015, Volume: 49

    Topics: Animals; Anti-Bacterial Agents; Anticonvulsants; gamma-Aminobutyric Acid; Humans; Nipecotic Acids; Phenobarbital; Phenytoin; Status Epilepticus; Tiagabine

2015
Pain management strategies for neuropathic pain in Fabry disease--a systematic review.
    BMC neurology, 2016, Feb-24, Volume: 16

    Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Fabry Disease; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Phenytoin

2016
[Preconceptional and perinatal challenges of pregnancy in women with epilepsy].
    Orvosi hetilap, 2016, Apr-10, Volume: 157, Issue:15

    Topics: Adult; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Parturition; Perinatal Care; Phenobarbital; Phenytoin; Piracetam; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Teratogens; Triazines; Valproic Acid

2016
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy.
    Journal of critical care, 2016, Volume: 36

    Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide

2016
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
    The Cochrane database of systematic reviews, 2017, 06-29, Volume: 6

    Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide

2017
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
    The Cochrane database of systematic reviews, 2017, 12-15, Volume: 12

    Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide

2017

Trials

12 trial(s) available for gamma-aminobutyric acid and phenytoin

ArticleYear
Compliant populations: variability in serum concentrations.
    Epilepsy research. Supplement, 1988, Volume: 1

    Topics: Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Felbamate; Female; gamma-Aminobutyric Acid; Humans; Male; Patient Compliance; Phenylcarbamates; Phenytoin; Propylene Glycols; Random Allocation

1988
A comparative study of progabide, valproate, and placebo as add-on therapy in patients with refractory epilepsy.
    Journal of neurology, neurosurgery, and psychiatry, 1986, Volume: 49, Issue:11

    Topics: Adolescent; Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Patient Compliance; Phenytoin; Valproic Acid

1986
A controlled study of progabide in partial seizures: methodology and results.
    Neurology, 1987, Volume: 37, Issue:6

    Topics: Adolescent; Adult; Carbamazepine; Clinical Trials as Topic; Female; gamma-Aminobutyric Acid; Humans; Male; Phenytoin; Seizures

1987
Effect of progabide on serum phenytoin and carbamazepine concentrations.
    Clinical neuropharmacology, 1987, Volume: 10, Issue:6

    Topics: Adult; Carbamazepine; Convulsants; Double-Blind Method; Drug Evaluation; Female; gamma-Aminobutyric Acid; Humans; Male; Phenytoin; Random Allocation; Seizures

1987
Progabide for refractory partial epilepsy: a controlled add-on trial.
    Neurology, 1986, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Random Allocation

1986
Efficacy and tolerability of vigabatrin in children with refractory partial seizures: a single-blind dose-increasing study.
    Epilepsia, 1995, Volume: 36, Issue:7

    Topics: Anticonvulsants; Child; Child, Preschool; Data Interpretation, Statistical; Epilepsies, Partial; Female; gamma-Aminobutyric Acid; Humans; Male; Phenytoin; Placebos; Single-Blind Method; Time Factors; Vigabatrin

1995
Effects of vigabatrin on motor potentials evoked with magnetic stimulation.
    Electroencephalography and clinical neurophysiology, 1997, Volume: 105, Issue:2

    Topics: Adult; Anticonvulsants; Differential Threshold; Electromyography; Evoked Potentials, Motor; gamma-Aminobutyric Acid; Hand; Humans; Magnetics; Male; Middle Aged; Muscles; Phenytoin; Physical Stimulation; Vigabatrin

1997
Outcome evaluation of gabapentin as add-on therapy for partial seizures. "NEON" Study Investigators Group. Neurontin Evaluation of Outcomes in Neurological Practice.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1998, Volume: 25, Issue:2

    Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurologic Examination; Phenobarbital; Phenytoin; Primidone; Quality of Life; Valproic Acid

1998
Safety and tolerability of gabapentin as adjunctive therapy in a large, multicenter study.
    Epilepsia, 1999, Volume: 40, Issue:7

    Topics: Acetates; Adolescent; Adult; Ambulatory Care; Amines; Anticonvulsants; Asthenia; Carbamazepine; Cyclohexanecarboxylic Acids; Dizziness; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Male; Patient Dropouts; Phenytoin; Prospective Studies; Treatment Outcome; Valproic Acid

1999
Gabapentin does not affect antipyrine clearance.
    Journal of clinical pharmacology, 1999, Volume: 39, Issue:9

    Topics: Acetates; Adult; Amines; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antipyrine; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Male; Phenytoin; Saliva

1999
Gabapentin as adjunctive therapy for partial seizures.
    Epilepsia, 1999, Volume: 40 Suppl 6

    Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dizziness; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Patient Dropouts; Phenytoin; Prospective Studies; Quality of Life; Sleep Stages; Treatment Outcome

1999
The analgesic effect of gabapentin as a prophylactic anticonvulsant drug on postcraniotomy pain: a prospective randomized study.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:5

    Topics: Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Intravenous; Anticonvulsants; Craniotomy; Cyclohexanecarboxylic Acids; Dizziness; Drug Administration Schedule; Fatigue; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intubation, Intratracheal; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Phenytoin; Piperidines; Preanesthetic Medication; Propofol; Prospective Studies; Remifentanil; Sleep; Supratentorial Neoplasms; Time Factors; Treatment Outcome

2009

Other Studies

136 other study(ies) available for gamma-aminobutyric acid and phenytoin

ArticleYear
Structure-activity studies on benzhydrol-containing nipecotic acid and guvacine derivatives as potent, orally-active inhibitors of GABA uptake.
    Journal of medicinal chemistry, 1992, Oct-30, Volume: 35, Issue:22

    Topics: Administration, Oral; Animals; Anticonvulsants; Benzhydryl Compounds; Blood-Brain Barrier; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Mice; Neurotransmitter Uptake Inhibitors; Nicotinic Acids; Nipecotic Acids; Proline; Rats; Structure-Activity Relationship

1992
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
New anticonvulsants: Schiff bases of gamma-aminobutyric acid and gamma-aminobutyramide.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:6

    Topics: Animals; Anticonvulsants; Bicuculline; Brain; Cerebellum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ganglia, Spinal; Humans; In Vitro Techniques; Lethal Dose 50; Male; Mice; Rats; Schiff Bases

1980
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Mechanism of action of anticonvulsants. Role of the differential effects on the active uptake of putative neurotransmitters.
    Neurology, 1976, Volume: 26, Issue:2

    Topics: Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Hypnotics and Sedatives; In Vitro Techniques; Neurotransmitter Agents; Norepinephrine; Pentobarbital; Phenytoin; Rats

1976
[Inhibitory processes in the cerebral cortex and the anticonvulsive action of benzodiazepine derivatives].
    Biulleten' eksperimental'noi biologii i meditsiny, 1977, Volume: 84, Issue:10

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Brain; Cats; Cerebral Cortex; Clonazepam; Diazepam; Electrophysiology; gamma-Aminobutyric Acid; Lorazepam; Medazepam; Neural Inhibition; Phenobarbital; Phenytoin; Seizures; Semicarbazides

1977
Further evidence for GABA-ergic mechanisms in the action of benzodiazepines.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 229, Issue:2

    Topics: Aminobutyrates; Animals; Anti-Anxiety Agents; Benzodiazepines; Bicuculline; Cats; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; Male; Mice; Phenobarbital; Phenytoin; Rabbits; Rats; Reflex; Sciatic Nerve; Thiosemicarbazones

1977
Effects of gaba, gabob and some anticonvulsant drugs on dibutyryl cyclic AMP evoked seizures.
    International journal of clinical pharmacology and biopharmacy, 1977, Volume: 15, Issue:1

    Topics: Aminobutyrates; Animals; Anticonvulsants; Bucladesine; Chickens; Diazepam; Electroencephalography; Female; gamma-Aminobutyric Acid; Phenobarbital; Phenytoin; Seizures

1977
Effect of combined dopaminergic and GABA-ergic stimulation on ouabain-induced epileptiform activity.
    Epilepsia, 1977, Volume: 18, Issue:4

    Topics: Aminooxyacetic Acid; Animals; Apomorphine; Cerebral Cortex; Drug Combinations; Drug Synergism; Electroencephalography; gamma-Aminobutyric Acid; Hydroxybutyrates; Male; Ouabain; Phenytoin; Rabbits; Receptors, Dopamine; Receptors, Neurotransmitter; Seizures

1977
Metabolite levels in brain following experimental seizures: the effects of maximal electroshock and phenytoin in cerebellar layers.
    Journal of neurochemistry, 1979, Volume: 32, Issue:3

    Topics: Adenosine Triphosphate; Animals; Brain; Cyclic AMP; Cyclic GMP; Electroshock; gamma-Aminobutyric Acid; Glucose; Glycogen; Kinetics; Lactates; Male; Mice; Phenytoin; Phosphocreatine; Purkinje Cells; Seizures

1979
Photosensitive epilepsy in Papio papio as a model for drug studies.
    Electroencephalography and clinical neurophysiology. Supplement, 1978, Issue:34

    Topics: Animals; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Haplorhini; Papio; Phenytoin; Photic Stimulation; Seizures; Serotonin; Synaptic Transmission

1978
Evidence for an involvement of GABA in the mediation of the cerebellar cGMP decrease and the anticonvulsant action diazepam.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 289, Issue:4

    Topics: Aminobutyrates; Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Cerebellum; Cyclic AMP; Cyclic GMP; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Isoniazid; Male; Pentylenetetrazole; Phenytoin; Picrotoxin; Rats; Strychnine

1975
Neurophysiological and neurochemical studies on the action of the anticonvulsant gamma-hydroxy, gamma-ethyl, gamma-phenyl-butyramide.
    Epilepsia, 1979, Volume: 20, Issue:2

    Topics: Amygdala; Animals; Anticonvulsants; Bicuculline; Brain; Cats; Cerebral Cortex; Drug Synergism; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Mice; Phenylbutyrates; Phenytoin; Potassium; Seizures; Strychnine; Substantia Nigra

1979
Competition for diazepam receptor binding by diphenylhydantoin and its enhancement by gamma-aminobutyric acid.
    Biochemical and biophysical research communications, 1979, Dec-14, Volume: 91, Issue:3

    Topics: Animals; Binding, Competitive; Cerebral Cortex; Diazepam; gamma-Aminobutyric Acid; Kinetics; Male; Phenytoin; Rats; Receptors, Drug; Synaptic Membranes

1979
Amino acids in human epileptogenic foci.
    Archives of neurology, 1975, Volume: 32, Issue:11

    Topics: Adolescent; Adult; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Child; Cystathionine; Epilepsies, Partial; gamma-Aminobutyric Acid; Glutamates; Glycine; Humans; Phenytoin; Rats; Taurine

1975
The mechanism of action of diphenylhydantoin on invertebrate neurons. II. Effects on synaptic mechanisms.
    Brain research, 1977, Volume: 121, Issue:2

    Topics: Acetylcholine; Action Potentials; Animals; Astacoidea; gamma-Aminobutyric Acid; Ganglia; In Vitro Techniques; Mechanoreceptors; Membrane Potentials; Mollusca; Neural Inhibition; Phenytoin; Synapses; Time Factors

1977
Phenytoin and cerebellar lesions. Similar effects on cerebral catecholamine metabolism.
    Archives of neurology, 1977, Volume: 34, Issue:3

    Topics: Animals; Brain; Catecholamines; Cerebellum; Dopamine; gamma-Aminobutyric Acid; Male; Norepinephrine; Phenytoin; Rats; Serotonin

1977
Effect of diphenylhydantoin on gamma aminobutyric acid (GABA) and succinate activity in rat Purkinje cells.
    Journal of neurology, neurosurgery, and psychiatry, 1977, Volume: 40, Issue:6

    Topics: Aminobutyrates; Animals; Cerebellum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Histocytochemistry; Injections, Intraperitoneal; Phenytoin; Purkinje Cells; Rats; Succinate Dehydrogenase

1977
Photically induced epilepsy in Papio papio as a model for drug studies.
    Advances in neurology, 1975, Volume: 10

    Topics: Acetylcholine; Animals; Carbamazepine; Clonazepam; Diazepam; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Glycine; Humans; Norepinephrine; Papio; Phenobarbital; Phenytoin; Photic Stimulation; Serotonin; Spasms, Infantile

1975
CNS depressants: effects on post-synaptic pharmacology.
    Brain research, 1975, Jul-04, Volume: 92, Issue:1

    Topics: Acetylcholine; Animals; Astacoidea; Chloralose; Chlorides; Chloroform; Dopamine; Dose-Response Relationship, Drug; Ethanol; gamma-Aminobutyric Acid; Glutamates; Membrane Potentials; Nephropidae; Neuromuscular Junction; Pentobarbital; Phenytoin; Potassium; Serotonin; Snails; Sodium; Synapses; Urethane; Vasopressins

1975
Diphenylhydantoin increases cortical postsynaptic inhibition.
    Brain research, 1976, Apr-09, Volume: 105, Issue:3

    Topics: Animals; Cats; Cerebral Cortex; gamma-Aminobutyric Acid; Membrane Potentials; Neural Inhibition; Phenytoin; Stimulation, Chemical; Synaptic Membranes

1976
Age dependency of the susceptibility of rats to aminooxyacetic acid seizures.
    Brain research. Developmental brain research, 1992, Jun-19, Volume: 67, Issue:2

    Topics: Aging; Aminooxyacetic Acid; Animals; Anticonvulsants; Body Temperature; Brain; Carbamazepine; Clonazepam; Disease Susceptibility; Electroencephalography; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Organ Specificity; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Time Factors; Valproic Acid

1992
Differential effects of selective mu-, kappa- and delta-opioid antagonists on electroshock seizure threshold in mice.
    Psychopharmacology, 1991, Volume: 103, Issue:3

    Topics: Animals; Anticonvulsants; Bicuculline; Dose-Response Relationship, Drug; Electroshock; gamma-Aminobutyric Acid; Indoles; Male; Mice; Mice, Inbred Strains; Morphinans; Naloxone; Naltrexone; Narcotic Antagonists; Phenytoin; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1991
Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.
    European journal of pharmacology, 1991, Jan-10, Volume: 192, Issue:2

    Topics: Animals; Baclofen; Carbamazepine; Cricetinae; Diazepam; Disease Models, Animal; Dystonia; gamma-Aminobutyric Acid; Mesocricetus; Mutation; Pentylenetetrazole; Phenobarbital; Phenytoin; Synaptic Transmission; Valproic Acid

1991
Comparison of gabapentin with other antiepileptic and GABAergic drugs.
    Epilepsy research, 1991, Volume: 8, Issue:3

    Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Carbamazepine; Cats; Cyclohexanecarboxylic Acids; Electric Stimulation; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Injections, Intravenous; Maxillary Nerve; Phenytoin; Reaction Time; Trigeminal Nuclei

1991
Effects of anticonvulsants and gamma-aminobutyric acid (GABA)-mimetic drugs on immunoreactive somatostatin and GABA contents in the rat brain.
    Life sciences, 1990, Volume: 46, Issue:22

    Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Brain Chemistry; Carbamazepine; Chromatography, Gel; Drug Interactions; Ethanolamines; gamma-Aminobutyric Acid; Male; Muscimol; Phenytoin; Rats; Rats, Inbred Strains; Somatostatin; Valproic Acid

1990
Anticonvulsants do not suppress long-term potentiation (LTP) in the rat hippocampus.
    Neuroscience letters, 1991, Jan-14, Volume: 122, Issue:1

    Topics: Animals; Anticonvulsants; Evoked Potentials; Female; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Midazolam; Phenytoin; Rats; Rats, Inbred Strains; Synapses

1991
Anticonvulsant drug mechanisms of action.
    Federation proceedings, 1985, Volume: 44, Issue:10

    Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Clonazepam; Electroshock; gamma-Aminobutyric Acid; Humans; Ion Channels; Membrane Potentials; Mice; Neurons; Phenobarbital; Phenytoin; Seizures; Valproic Acid

1985
Excitatory and inhibitory neurotransmitters in the generation and degeneration of hippocampal neuroarchitecture.
    Brain research, 1989, Jan-30, Volume: 478, Issue:2

    Topics: Animals; Anticonvulsants; Carbamazepine; Cell Survival; Cells, Cultured; Dendrites; Diazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Phenytoin; Rats

1989
[Mechanism of action of antiepileptic drugs].
    Revue neurologique, 1987, Volume: 143, Issue:5

    Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; gamma-Aminobutyric Acid; Ion Exchange; Phenobarbital; Phenytoin; Receptors, Neurotransmitter; Synaptic Transmission; Valproic Acid

1987
Antiepileptic drugs and cerebral glucose metabolism.
    Epilepsia, 1988, Volume: 29 Suppl 2

    Topics: Anticonvulsants; Brain; Carbamazepine; gamma-Aminobutyric Acid; Glucose; Humans; Phenobarbital; Phenytoin; Receptors, GABA-A; Tomography, Emission-Computed

1988
Antiepileptic drug phenytoin potentiates GABA in the rat cuneate nucleus.
    The Japanese journal of psychiatry and neurology, 1988, Volume: 42, Issue:3

    Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; Hypothalamus; Male; Mesencephalon; Phenytoin; Rats; Rats, Inbred Strains; Receptors, GABA-A

1988
Effects of anticonvulsant drugs on brain cultures from chick embryos: a comparison with cultures from embryos treated in ovo.
    Teratogenesis, carcinogenesis, and mutagenesis, 1985, Volume: 5, Issue:3

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Brain; Carbonic Anhydrases; Cells, Cultured; Chick Embryo; Choline O-Acetyltransferase; gamma-Aminobutyric Acid; Kinetics; Neurons; Phenobarbital; Phenytoin; Valproic Acid

1985
Carbamazepine and 10,11-epoxycarbamazepine produce use- and voltage-dependent limitation of rapidly firing action potentials of mouse central neurons in cell culture.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:2

    Topics: Action Potentials; Animals; Carbamazepine; Cells, Cultured; Central Nervous System; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Membrane Potentials; Mice; Neurons; Phenytoin; Sodium; Spinal Cord

1986
The effect of phenytoin on glutamate and GABA transport.
    Neurochemical research, 1986, Volume: 11, Issue:9

    Topics: Animals; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Neurotransmitter Uptake Inhibitors; Phenytoin; Rats; Synaptosomes

1986
Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3

    Topics: Action Potentials; Animals; Carbamazepine; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Ethosuximide; gamma-Aminobutyric Acid; Magnesium; Mice; Neurons; Phenytoin; Seizures; Sodium; Spinal Cord; Valproic Acid

1986
Changes in GABA content of the brain and sensitivity to GABA-antagonists during and after repetitive treatment of rats with diphenilhydantoin.
    Folia medica, 1988, Volume: 30, Issue:3

    Topics: Animals; Brain; Electroshock; GABA Antagonists; gamma-Aminobutyric Acid; Male; Pentylenetetrazole; Phenytoin; Picrotoxin; Rats; Rats, Inbred Strains; Seizures

1988
N-demethylation of methyl and dimethyl derivatives of phenytoin and their anticonvulsant activities in mice.
    Japanese journal of pharmacology, 1988, Volume: 48, Issue:4

    Topics: Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Electroshock; gamma-Aminobutyric Acid; Hydantoins; Injections, Intraperitoneal; Male; Mephenytoin; Mice; Mice, Inbred Strains; Phenytoin; Radioligand Assay

1988
Effects of diazepam, pentobarbital, phenytoin and pentylenetetrazol on hippocampal paired-pulse inhibition in vivo.
    Neuroscience letters, 1986, Apr-24, Volume: 65, Issue:3

    Topics: Action Potentials; Animals; Behavior, Animal; Diazepam; Electroshock; gamma-Aminobutyric Acid; Hippocampus; Injections, Intraperitoneal; Male; Neural Inhibition; Pentobarbital; Pentylenetetrazole; Phenytoin; Rats; Rats, Inbred Strains; Seizures

1986
Phenytoin increases the severity of cortical hemiplegia in rats.
    Brain research, 1986, Jun-18, Volume: 376, Issue:1

    Topics: Animals; gamma-Aminobutyric Acid; Hemiplegia; Male; Motor Activity; Motor Cortex; Phenytoin; Rats; Rats, Inbred F344; Severity of Illness Index

1986
Involvement of a GABAergic mechanism in the pharmacologic action of phenytoin.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:5

    Topics: Animals; Anticonvulsants; Baclofen; Electroshock; gamma-Aminobutyric Acid; Male; Mice; Phenytoin; Postural Balance; Seizures

1986
Fast recording ion specific microelectrodes: their use in pharmacological studies in the CNS.
    Neuropharmacology, 1974, Volume: 13, Issue:6

    Topics: Acetylcholine; Animals; Bucladesine; Cats; Central Nervous System; Cerebral Cortex; Chlorides; Electric Conductivity; Electric Stimulation; Extracellular Space; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamates; Ion Exchange; Iontophoresis; Microelectrodes; Neurons; Norepinephrine; Pentobarbital; Phenytoin; Potassium; Potassium Chloride; Quaternary Ammonium Compounds; Tracheotomy

1974
Release of (3H)gamma-aminobutyric acid from glial cells in rat dorsal root ganglia.
    Journal of neurochemistry, 1974, Volume: 23, Issue:3

    Topics: Acetates; Alanine; Aminobutyrates; Animals; Calcium; Carbon Radioisotopes; gamma-Aminobutyric Acid; Ganglia, Spinal; Glutamates; Glycine; Hydroxylamines; Kinetics; L-Lactate Dehydrogenase; Lanthanum; Leucine; Magnesium; Neuroglia; Osmolar Concentration; Phenytoin; Potassium; Rats; Time Factors; Tritium

1974
Changes in regional brain levels of amino acid putative neurotransmitters after prolonged treatment with the anticonvulsant drugs diphenylhydantoin, phenobarbitone, sodium valproate, ethosuximide, and sulthiame in the rat.
    Journal of neurochemistry, 1981, Volume: 36, Issue:2

    Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Ethosuximide; gamma-Aminobutyric Acid; Glutamates; Male; Neurotransmitter Agents; Organ Specificity; Phenobarbital; Phenytoin; Rats; Taurine; Thiazines; Valproic Acid

1981
Noncatecholaminergic treatments of tardive dyskinesia.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:6

    Topics: Amantadine; Anti-Anxiety Agents; Benzodiazepines; Cyproheptadine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Double-Blind Method; Dyskinesia, Drug-Induced; Enkephalin, Methionine; gamma-Aminobutyric Acid; Humans; Lithium; Parasympathomimetics; Phenytoin; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, GABA-A; Substance Withdrawal Syndrome; Tryptophan

1982
The effects of convulsant and anticonvulsant drugs on the release of radiolabeled GABA, glutamate, noradrenaline, serotonin and acetylcholine from rat cortical slices.
    Brain research, 1982, Dec-16, Volume: 253, Issue:1-2

    Topics: Acetylcholine; Animals; Anticonvulsants; Cerebral Cortex; Culture Techniques; Diazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Norepinephrine; Phenobarbital; Phenytoin; Potassium; Prohibitins; Rats; Rats, Inbred Strains; Seizures; Serotonin

1982
Studies on benzodiazepine receptors.
    Advances in biochemical psychopharmacology, 1980, Volume: 21

    Topics: Animals; Benzodiazepines; Binding Sites; Cerebral Cortex; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ligands; Methyltransferases; Muscimol; Neural Inhibition; Phenytoin; Phospholipids; Rats; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter

1980
Receptor modeling for anticonvulsant and convulsant drugs.
    Advances in neurology, 1980, Volume: 27

    Topics: Acetylcholine; Animals; Anticonvulsants; Convulsants; gamma-Aminobutyric Acid; Humans; Ion Channels; Lipid Metabolism; Models, Biological; Phenytoin; Protein Binding; Receptors, Drug; Receptors, Nicotinic; Structure-Activity Relationship; Strychnine

1980
The effects of pentobarbital and related compounds on frog motoneurons.
    Brain research, 1980, Jun-02, Volume: 191, Issue:1

    Topics: Amino Acids; Animals; Anura; Bicuculline; Chloralose; Chlordiazepoxide; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Motor Neurons; Muscimol; Pentobarbital; Phenobarbital; Phenytoin; Picrotoxin; Spinal Cord; Strychnine; Synaptic Transmission

1980
Effect of dopaminergic and GABA-ergic drugs given alone or in combination on the anticonvulsant action of phenobarbital and diphenylhydantoin in the electroshock test in mice.
    Epilepsia, 1980, Volume: 21, Issue:5

    Topics: Amantadine; Aminooxyacetic Acid; Amphetamine; Animals; Apomorphine; Baclofen; Dopamine; Electroshock; Female; Fluphenazine; gamma-Aminobutyric Acid; Haloperidol; Hydroxybutyrates; Levodopa; Male; Mice; Phenobarbital; Phenytoin; Receptors, Neurotransmitter; Seizures

1980
A comparison of the effects of pentobarbital and diphenylhydantoin on the GABA sensitivity and excitability of adult sensory ganglion cells.
    Brain research, 1981, Mar-02, Volume: 207, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Pentobarbital; Phenytoin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Tetrodotoxin; Veratridine

1981
Voltage clamp analysis of inhibitory synaptic action in crayfish stretch receptor neurons.
    Federation proceedings, 1981, Volume: 40, Issue:11

    Topics: Animals; Astacoidea; Electric Conductivity; gamma-Aminobutyric Acid; Ion Channels; Mechanoreceptors; Membrane Potentials; Neural Inhibition; Phenytoin; Picrotoxin; Synapses

1981
Prenatal exposure to electroconvulsive seizures and phenytoin: development of benzodiazepine binding sites, reflex behaviors and seizure thresholds in exposed offspring.
    European journal of pharmacology, 1982, Nov-19, Volume: 85, Issue:2

    Topics: Animals; Animals, Newborn; Brain; Electroshock; Female; Fetus; gamma-Aminobutyric Acid; Phenytoin; Pregnancy; Rats; Receptors, Cell Surface; Receptors, GABA-A; Reflex; Seizures

1982
Cyclic GMP and cyclic AMP in the cerebral cortex of mice during seizures induced by 3-mercaptopropionic acid: effects of anticonvulsant agents.
    Neuroscience letters, 1980, Volume: 16, Issue:3

    Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Cerebral Cortex; Cyclic AMP; Cyclic GMP; gamma-Aminobutyric Acid; Hybridization, Genetic; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Phenobarbital; Phenytoin; Seizures

1980
Enhancement of 3H-phenytoin binding by diazepam and (+)bicuculline.
    Life sciences, 1983, Aug-01, Volume: 33, Issue:5

    Topics: Animals; Bicuculline; Brain; Diazepam; gamma-Aminobutyric Acid; Kinetics; Male; Phenytoin; Rats; Receptors, Cell Surface; Receptors, GABA-A

1983
Multiple actions of phenytoin on mouse spinal cord neurons in cell culture.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:3

    Topics: Action Potentials; Animals; Anticonvulsants; Calcium; Cells, Cultured; Culture Media; Depression, Chemical; Embryo, Mammalian; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Mice; Microelectrodes; Neurons; Phenytoin; Spinal Cord; Synaptic Transmission

1983
In vivo effects of phenytoin and phenobarbital on GABA receptors in rat cerebral cortex and cerebellum.
    Neuroscience letters, 1984, May-18, Volume: 46, Issue:3

    Topics: Animals; Cerebellum; Cerebral Cortex; gamma-Aminobutyric Acid; Kinetics; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A

1984
Possible mechanism of digoxin-induced convulsions.
    Psychopharmacology, 1983, Volume: 79, Issue:2-3

    Topics: Animals; Calcium Chloride; Clonidine; Diazepam; Digoxin; Female; gamma-Aminobutyric Acid; Magnesium; Magnesium Chloride; Male; Phenytoin; Piracetam; Potassium Chloride; Rats; Rats, Inbred Strains; Seizures

1983
Effects of some anticonvulsant drugs on brain GABA level and GAD and GABA-T activities.
    Neurochemical research, 1984, Volume: 9, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Oxidoreductases; Phenobarbital; Phenytoin; Valproic Acid

1984
Penicillin spikes in rats. Limitations of a simple model for the study of anticonvulsants.
    Neuropharmacology, 1984, Volume: 23, Issue:9

    Topics: Action Potentials; Animals; Anticonvulsants; Dimethyl Sulfoxide; Disease Models, Animal; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Isoxazoles; Male; Penicillins; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Taurine; Time Factors

1984
Differential effects of baclofen, gamma-hydroxybutyric acid and muscimol on the protective action of phenobarbital and diphenylhydantoin against maximal electroshock-induced seizures in mice.
    Neuropharmacology, 1984, Volume: 23, Issue:2A

    Topics: Animals; Anticonvulsants; Baclofen; Drug Interactions; Electroshock; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections, Intraventricular; Male; Mice; Muscimol; Oxazoles; Phenobarbital; Phenytoin; Sodium Oxybate

1984
Anticonvulsant activation of pain-suppressive systems.
    Applied neurophysiology, 1982, Volume: 45, Issue:6

    Topics: Aldehyde Oxidoreductases; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Male; Neural Inhibition; Nociceptors; Periaqueductal Gray; Phenytoin; Rats; Rats, Inbred Strains; Succinate-Semialdehyde Dehydrogenase; Valproic Acid

1982
Toxic effect of phenytoin on developing cortical neurons in culture.
    Annals of neurology, 1983, Volume: 13, Issue:1

    Topics: Animals; Cell Count; Cells, Cultured; Cerebral Cortex; Fetus; gamma-Aminobutyric Acid; Mice; Neurons; Phenytoin

1983
Cellular bases of barbiturate and phenytoin anticonvulsant drug action.
    Epilepsia, 1982, Volume: 23 Suppl 1

    Topics: Animals; Barbiturates; Bicuculline; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Neurons; Pentobarbital; Phenobarbital; Phenytoin; Synapses

1982
Opposite effects of 5,5-diphenylhydantoin and picrotoxin on GABAergic inhibition in crayfish stretch receptor.
    Advances in biochemical psychopharmacology, 1981, Volume: 29

    Topics: Animals; Astacoidea; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Mechanoreceptors; Membrane Potentials; Phenytoin; Picrotoxin

1981
Opposing actions of convulsants and anticonvulsants on GABA responses of crayfish stretch receptors.
    Advances in biochemical psychopharmacology, 1981, Volume: 29

    Topics: Animals; Anticonvulsants; Astacoidea; Convulsants; gamma-Aminobutyric Acid; In Vitro Techniques; Mechanoreceptors; Membrane Potentials; Phenytoin; Picrotoxin; Synapses

1981
[Pharmacological influences on the brain level and transport of GABA. I) Effect of various antipileptic drugs on brain levels of GABA].
    Bollettino della Societa italiana di biologia sperimentale, 1981, Apr-30, Volume: 57, Issue:8

    Topics: Animals; Biological Transport; Brain; Carbamazepine; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Mice; Phenobarbital; Phenytoin

1981
On the action of the anticonvulsant 5,5-diphenylhydantoin and the convulsant picrotoxin in crayfish stretch receptor.
    The Journal of physiology, 1981, Volume: 315

    Topics: Action Potentials; Animals; Astacoidea; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Mechanoreceptors; Membrane Potentials; Neural Inhibition; Phenytoin; Picrotoxin

1981
Effects of the peptide BCH-325 upon the efficacy of common antiepileptic drugs.
    Peptides, 1994, Volume: 15, Issue:7

    Topics: Amino Acid Sequence; Animals; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Molecular Sequence Data; Peptide Fragments; Phenobarbital; Phenytoin; Seizures; Sodium Channels; Synaptic Transmission; Valproic Acid

1994
Interaction of gabapentin with other antiepileptics.
    Lancet (London, England), 1994, May-28, Volume: 343, Issue:8909

    Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Phenytoin

1994
Epilepsy treatment in The Netherlands. Comparison of matched groups of two medical centres.
    Acta neurologica Scandinavica, 1994, Volume: 89, Issue:6

    Topics: Adolescent; Adult; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Female; gamma-Aminobutyric Acid; Humans; Male; Netherlands; Phenobarbital; Phenytoin; Primidone; Quality of Health Care; Statistics, Nonparametric; Treatment Outcome; Valproic Acid; Vigabatrin

1994
Differential effects of phenytoin and sodium valproate on seizure-induced changes in gamma-aminobutyric acid and glutamate release in vivo.
    European journal of pharmacology, 1995, Dec-29, Volume: 294, Issue:2-3

    Topics: Animals; Anticonvulsants; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Phenytoin; Rats; Seizures; Valproic Acid

1995
Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus.
    Methods and findings in experimental and clinical pharmacology, 1996, Volume: 18, Issue:5

    Topics: Animals; Anticonvulsants; Baclofen; Clonazepam; Diazepam; Dizocilpine Maleate; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Lithium Chloride; Male; Neuroprotective Agents; Pentobarbital; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid

1996
Colonic absorption of antiepileptic agents.
    Epilepsia, 1997, Volume: 38, Issue:1

    Topics: Acetates; Amines; Animals; Anticonvulsants; Biological Transport; Chromatography, High Pressure Liquid; Colon; Cyclohexanecarboxylic Acids; Dogs; Drug Overdose; Gabapentin; gamma-Aminobutyric Acid; Instillation, Drug; Intestinal Absorption; Intestine, Small; Phenytoin

1997
The effects of anticonvulsant drugs on NMDA-EPSP, AMPA-EPSP, and GABA-IPSP in the rat hippocampus.
    Brain research bulletin, 1997, Volume: 42, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; Male; N-Methylaspartate; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Valproic Acid

1997
Vigabatrin-induced gingival overgrowth.
    Journal of clinical periodontology, 1997, Volume: 24, Issue:3

    Topics: Adult; Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Epilepsy, Complex Partial; Female; Follow-Up Studies; gamma-Aminobutyric Acid; Gingival Overgrowth; Humans; Immunosuppressive Agents; Phenytoin; Vigabatrin

1997
Vigabatrin versus carbamazepine and phenytoin in kainic acid-treated pubescent rats.
    Pharmacological research, 1997, Volume: 36, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Enzyme Inhibitors; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Kainic Acid; Male; Phenytoin; Rats; Rats, Wistar; Vigabatrin

1997
Effects of phenytoin on the amygdala neurons in vitro.
    Pharmacology, 1997, Volume: 55, Issue:5

    Topics: Amygdala; Animals; Anticonvulsants; Calcium; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Phenytoin; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission

1997
Effects of phenytoin, carbamazepine, and gabapentin on calcium channels in hippocampal granule cells from patients with temporal lobe epilepsy.
    Epilepsia, 1998, Volume: 39, Issue:4

    Topics: Acetates; Adult; Amines; Anticonvulsants; Calcium Channels; Carbamazepine; Cyclohexanecarboxylic Acids; Dentate Gyrus; Epilepsy, Temporal Lobe; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Humans; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phenytoin; Pyramidal Cells

1998
Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats.
    European journal of pharmacology, 1998, Sep-25, Volume: 358, Issue:1

    Topics: Acetates; Amines; Animals; Anticonvulsants; Biogenic Amines; Blood Platelets; Brain; Carbamazepine; Cyclohexanecarboxylic Acids; Dopamine; Dopamine Uptake Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium; Male; Norepinephrine; p-Chloroamphetamine; Phenytoin; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Syndrome; Synaptosomes; Tetrodotoxin; Triazines; Valproic Acid; Zonisamide

1998
[Drug-resistant epilepsy].
    Revista de neurologia, 1998, Volume: 27, Issue:159

    Topics: Adult; Anticonvulsants; Brain Neoplasms; Calcinosis; Carbamazepine; Diagnosis, Differential; Drug Resistance; Drug Therapy, Combination; Electroencephalography; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Glioma; Humans; Magnetic Resonance Imaging; Neoplasms, Germ Cell and Embryonal; Neoplasms, Neuroepithelial; Phenytoin; Temporal Lobe; Tomography, Emission-Computed, Single-Photon; Valproic Acid; Vigabatrin

1998
Focal lesion in the splenium of the corpus callosum in epileptic patients: antiepileptic drug toxicity?
    AJNR. American journal of neuroradiology, 1999, Volume: 20, Issue:1

    Topics: Adult; Anticonvulsants; Corpus Callosum; Epilepsy, Complex Partial; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Male; Phenytoin; Vigabatrin

1999
An in vitro electrophysiological study on the effects of phenytoin, lamotrigine and gabapentin on striatal neurons.
    British journal of pharmacology, 1999, Volume: 126, Issue:3

    Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Cerebral Cortex; Corpus Striatum; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Lamotrigine; Male; Membrane Potentials; Neurons; Phenytoin; Rats; Rats, Wistar; Triazines

1999
Focal lesion in the splenium of the corpus callosum in epileptic patients: antiepileptic drug toxicity?
    AJNR. American journal of neuroradiology, 1999, Volume: 20, Issue:1

    Topics: Anticonvulsants; Corpus Callosum; Epilepsy, Complex Partial; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Phenytoin; Vigabatrin

1999
Successful treatment with gabapentin in the presence of hypersensitivity syndrome to phenytoin and carbamazepine: a report of three cases.
    Seizure, 1999, Volume: 8, Issue:3

    Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Hypersensitivity; Drug Interactions; Epilepsy, Complex Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Phenytoin; Valproic Acid

1999
Effects of anticonvulsant lactams on in vitro seizures in the hippocampal slice preparation.
    Epilepsy research, 1999, Volume: 37, Issue:2

    Topics: 4-Butyrolactone; Animals; Anticonvulsants; Calcium Channel Blockers; Electrophysiology; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Lactams; Mice; Phenytoin; Piperidines; Potassium Channel Blockers; Receptors, GABA-A; Seizures; Sodium Channel Blockers; Synaptic Transmission

1999
Anticonvulsant activity of PNU-151774E in the amygdala kindled model of complex partial seizures.
    Epilepsia, 1999, Volume: 40, Issue:11

    Topics: Acetates; Alanine; Amines; Amygdala; Animals; Anticonvulsants; Behavior, Animal; Benzylamines; Carbamazepine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Gabapentin; gamma-Aminobutyric Acid; Kindling, Neurologic; Lamotrigine; Male; Phenytoin; Rats; Rats, Wistar; Severity of Illness Index; Triazines

1999
Reciprocal modulation of glutamate and GABA release may underlie the anticonvulsant effect of phenytoin.
    Neuroscience, 2000, Volume: 95, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Brain Chemistry; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neural Inhibition; Patch-Clamp Techniques; Phenytoin; Phosphinic Acids; Propanolamines; Rats; Rats, Wistar; Synapses; Synaptic Transmission

2000
Effects of standard anticonvulsant drugs on different patterns of epileptiform discharges induced by 4-aminopyridine in combined entorhinal cortex-hippocampal slices.
    Brain research, 2000, Mar-17, Volume: 859, Issue:1

    Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbamazepine; Entorhinal Cortex; Epilepsies, Partial; Female; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Male; Pentobarbital; Phenobarbital; Phenytoin; Prohibitins; Rats; Rats, Wistar; Valproic Acid

2000
Improved sexual function in three men taking lamotrigine for epilepsy.
    Southern medical journal, 2000, Volume: 93, Issue:3

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Erectile Dysfunction; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sexual Dysfunctions, Psychological; Triazines; Valproic Acid

2000
Synthesis and anticonvulsant and neurotoxic properties of substituted N-phenyl derivatives of the phthalimide pharmacophore.
    Journal of medicinal chemistry, 2000, Apr-06, Volume: 43, Issue:7

    Topics: Administration, Oral; Animals; Anticonvulsants; Batrachotoxins; Cerebral Cortex; Convulsants; Electroshock; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; Kainic Acid; Magnesium Deficiency; Mice; N-Methylaspartate; Patch-Clamp Techniques; Pentylenetetrazole; Phenytoin; Phthalimides; Rats; Seizures; Sodium Channel Blockers; Structure-Activity Relationship; Synaptosomes; Tumor Cells, Cultured

2000
Anticonvulsant efficacy of gabapentin and levetiracetam in phenytoin-resistant kindled rats.
    Epilepsy research, 2000, Volume: 40, Issue:1

    Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Evaluation; Drug Resistance; Female; Gabapentin; gamma-Aminobutyric Acid; Kindling, Neurologic; Levetiracetam; Phenytoin; Piracetam; Rats; Rats, Wistar; Seizures

2000
Effect of vigabatrin and gabapentin on phenytoin pharmacokinetics in the dog.
    Pharmacological research, 2000, Volume: 42, Issue:6

    Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dogs; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Male; Phenytoin; Vigabatrin

2000
Dendrotoxin sensitive potassium channels modulate GABA but not glutamate release in the rat entorhinal cortex in vitro.
    Neuroscience, 2001, Volume: 107, Issue:3

    Topics: Animals; Anticonvulsants; Elapid Venoms; Entorhinal Cortex; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Neural Inhibition; Neurotoxins; Peptides; Phenytoin; Potassium Channels; Rats; Rats, Wistar; Synaptic Transmission

2001
Effect of some antiepileptic drugs on brain histaminergic systems in the rat.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51 Suppl 1

    Topics: Acetates; Amines; Animals; Anticonvulsants; Brain Chemistry; Cyclohexanecarboxylic Acids; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Histamine; Methylhistamines; Phenytoin; Rats; Rats, Wistar

2002
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
    Neuroscience letters, 2003, Jan-02, Volume: 335, Issue:3

    Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid

2003
Potent analgesic effects of anticonvulsants on peripheral thermal nociception in rats.
    British journal of pharmacology, 2003, Volume: 140, Issue:2

    Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Female; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Neurons, Afferent; Pain Measurement; Peripheral Nervous System Diseases; Phenytoin; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers

2003
A NEUROPHARMACOLOGICAL STUDY OF GAMMA-AMINOBUTYRIC ACID (GABA).
    Archives internationales de pharmacodynamie et de therapie, 1964, Aug-01, Volume: 150

    Topics: Aminobutyrates; Anesthesia; Anesthesia, Intravenous; Behavior, Animal; Brain Chemistry; Cats; Chlorpromazine; Electroencephalography; Electroshock; gamma-Aminobutyric Acid; Hydroxylamines; Metabolism; Neuropharmacology; Pentobarbital; Pentylenetetrazole; Pharmacology; Phenytoin; Research; Reserpine; Seizures; Strychnine; Toxicology

1964
Potentially inappropriate antiepileptic drugs for elderly patients with epilepsy.
    Journal of the American Geriatrics Society, 2004, Volume: 52, Issue:3

    Topics: Acetates; Aged; Amines; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Phenytoin; Retrospective Studies; Triazines

2004
Treatment with the antiepileptic drugs phenytoin and gabapentin ameliorates seizure and paralysis of Drosophila bang-sensitive mutants.
    Journal of neurobiology, 2004, Volume: 58, Issue:4

    Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drosophila; Drosophila Proteins; Gabapentin; gamma-Aminobutyric Acid; Mutation; Paralysis; Phenytoin; Seizures

2004
Interaction between anticonvulsants and human placental carnitine transporter.
    Epilepsia, 2004, Volume: 45, Issue:3

    Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techniques; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Models, Biological; Nipecotic Acids; Organic Cation Transport Proteins; Phenytoin; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Proteins; Solute Carrier Family 22 Member 5; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin

2004
Profiles in patient safety: when an error occurs.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2004, Volume: 11, Issue:7

    Topics: Acetates; Aged; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Administration Schedule; Emergency Medicine; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypotension; Hypoxia; Medication Errors; Pain; Phenytoin; Treatment Outcome

2004
[Anticonvulsant hypersensitivity syndrome].
    Orvosi hetilap, 2004, Aug-08, Volume: 145, Issue:32

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Hypersensitivity; Ethosuximide; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lymphatic Diseases; Phenobarbital; Phenytoin; Syndrome; Triazines; Valproic Acid

2004
Pregabalin drug interaction studies: lack of effect on the pharmacokinetics of carbamazepine, phenytoin, lamotrigine, and valproate in patients with partial epilepsy.
    Epilepsia, 2005, Volume: 46, Issue:9

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsies, Partial; Female; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Pregabalin; Triazines; Valproic Acid

2005
Bronchial epilepsy or broncho-pulmonary hyper-excitability as a model of asthma pathogenesis.
    Medical hypotheses, 2006, Volume: 67, Issue:5

    Topics: Airway Obstruction; Asthma; Bronchi; Bronchial Hyperreactivity; Cell Membrane; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hyperventilation; Lidocaine; Male; Membrane Potentials; Models, Biological; Neurotransmitter Agents; Phenytoin; Respiration Disorders; Sodium Channels

2006
Anticonvulsant hypersensitivity syndrome: cross-reactivity with tricyclic antidepressant agents.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Benzodiazepines; Carbamazepine; Cross Reactions; Cyclohexanecarboxylic Acids; Doxepin; Drug Hypersensitivity; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Molecular Structure; Phenytoin; Skin Tests; Syndrome; Valproic Acid

2006
Effects of phenytoin and carbamazepine on calcium transport in Caco-2 cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2007, Volume: 21, Issue:5

    Topics: Amines; Anticonvulsants; Biological Transport, Active; Bone Diseases; Caco-2 Cells; Calcium; Carbamazepine; Cell Membrane Permeability; Cyclohexanecarboxylic Acids; Epithelial Cells; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenytoin; Topiramate; Vitamin D

2007
Status epilepticus secondary to hypertensive encephalopathy as the presenting manifestation of Guillain-Barré syndrome.
    Pediatric emergency care, 2007, Volume: 23, Issue:9

    Topics: Adolescent; Amines; Anticonvulsants; Antihypertensive Agents; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Electroencephalography; Female; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Humans; Hypertensive Encephalopathy; Immunoglobulins; Labetalol; Phenytoin; Spinal Puncture; Status Epilepticus; Tomography, X-Ray Computed

2007
Felbamate but not phenytoin or gabapentin reduces glutamate release by blocking presynaptic NMDA receptors in the entorhinal cortex.
    Epilepsy research, 2007, Volume: 77, Issue:2-3

    Topics: 2-Amino-5-phosphonovalerate; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Patch-Clamp Techniques; Phenylcarbamates; Phenytoin; Propylene Glycols; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic

2007
The effect of gabapentin and phenytoin on sperm-morphology in Wistar rats.
    Reproductive biology, 2007, Volume: 7, Issue:3

    Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Cyclophosphamide; Gabapentin; gamma-Aminobutyric Acid; Male; Mutagens; Phenytoin; Rats; Rats, Wistar; Spermatozoa

2007
Drug use in porphyria: a therapeutic dilemma.
    Singapore medical journal, 2008, Volume: 49, Issue:10

    Topics: Abdominal Pain; Adult; Amines; Anticonvulsants; Antiemetics; Antihypertensive Agents; Chest Pain; Cyclohexanecarboxylic Acids; Diazepam; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenytoin; Porphyria, Acute Intermittent; Promethazine; Propranolol; Vomiting

2008
Craniotomy pain: trying to do better.
    Anesthesia and analgesia, 2009, Volume: 109, Issue:5

    Topics: Administration, Oral; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anticonvulsants; Craniotomy; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; Pain Measurement; Pain, Postoperative; Phenytoin; Preanesthetic Medication; Supratentorial Neoplasms; Time Factors; Treatment Outcome

2009
Antiepileptic drugs combined with high-frequency electrical stimulation in the ventral hippocampus modify pilocarpine-induced status epilepticus in rats.
    Epilepsia, 2010, Volume: 51, Issue:3

    Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electric Stimulation; Electrodes, Implanted; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Lithium Chloride; Male; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Synaptic Transmission

2010
Anticonvulsant activity of Benkara malabarica (Linn.) root extract: In vitro and in vivo investigation.
    Journal of ethnopharmacology, 2010, Mar-24, Volume: 128, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Diazepam; Drug Interactions; Enzyme Assays; gamma-Aminobutyric Acid; Lethal Dose 50; Male; Mice; Phenytoin; Phytotherapy; Plant Extracts; Plant Roots; Rats; Rats, Wistar; Rubiaceae; Scopoletin; Seizures

2010
In vitro effects of antiepileptic drugs on acetylcholinesterase and ectonucleotidase activities in zebrafish (Danio rerio) brain.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:4

    Topics: 5'-Nucleotidase; Acetylcholinesterase; Amines; Animals; Anticonvulsants; Brain; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Phenytoin; Zebrafish

2010
Comparative effectiveness of 10 antiepileptic drugs in older adults with epilepsy.
    Archives of neurology, 2010, Volume: 67, Issue:4

    Topics: Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Resistance; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Treatment Outcome; Triazines

2010
Genotoxic evaluation of antiepileptic drugs by Drosophila somatic mutation and recombination test.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:10

    Topics: Abnormalities, Drug-Induced; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drosophila melanogaster; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Mutagenicity Tests; Mutagens; Phenytoin; Pregabalin; Recombination, Genetic; Survival; Wings, Animal

2010
Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population.
    Seizure, 2010, Volume: 19, Issue:9

    Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Child; China; Clonazepam; Cyclohexanecarboxylic Acids; Exanthema; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Medicine, Chinese Traditional; Middle Aged; Phenobarbital; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Triazines; Valproic Acid; Young Adult

2010
Effects of antiepileptic drugs on GABA release from rat and human neocortical synaptosomes.
    Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 384, Issue:1

    Topics: Adolescent; Adult; Aged; Amines; Animals; Anticonvulsants; Calcium; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Neocortex; Nipecotic Acids; Oximes; Phenytoin; Piracetam; Potassium; Pregabalin; Rats; Rats, Wistar; Synaptosomes; Tetanus Toxin; Tetrodotoxin; Triazines; Valproic Acid; Veratridine; Young Adult

2011
Effects of high frequency electrical stimulation and R-verapamil on seizure susceptibility and glutamate and GABA release in a model of phenytoin-resistant seizures.
    Neuropharmacology, 2011, Volume: 61, Issue:4

    Topics: Animals; Disease Models, Animal; Disease Susceptibility; Drug Resistance; Electric Stimulation; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Male; Phenytoin; Rats; Rats, Wistar; Seizures; Stereoisomerism; Verapamil

2011
Vinpocetine inhibits glutamate release induced by the convulsive agent 4-aminopyridine more potently than several antiepileptic drugs.
    Epilepsy research, 2011, Volume: 96, Issue:3

    Topics: 4-Aminopyridine; Animals; Anticonvulsants; Calcium; Carbamazepine; Drug Interactions; Epilepsy; Fructose; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Lamotrigine; Male; Nerve Endings; Oxcarbazepine; Phenytoin; Potassium Channel Blockers; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Tetrodotoxin; Topiramate; Triazines; Tritium; Vinca Alkaloids

2011
Low-magnesium medium induces epileptiform activity in mouse olfactory bulb slices.
    Journal of neurophysiology, 2011, Volume: 106, Issue:5

    Topics: Action Potentials; Acute Disease; Animals; Animals, Outbred Strains; Anticonvulsants; Culture Media; Electrophysiology; Epilepsy, Generalized; gamma-Aminobutyric Acid; Glutamic Acid; Magnesium; Magnesium Deficiency; Male; Mice; Neural Inhibition; Neurons; Olfactory Bulb; Organ Culture Techniques; Phenytoin; Potassium; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sodium

2011
Phenytoin, levetiracetam, and pregabalin in the acute management of refractory status epilepticus in patients with brain tumors.
    Neurocritical care, 2012, Volume: 16, Issue:1

    Topics: Acute Disease; Aged; Anticonvulsants; Brain Neoplasms; Drug Therapy, Combination; Female; gamma-Aminobutyric Acid; Humans; Levetiracetam; Male; Middle Aged; Phenytoin; Piracetam; Pregabalin; Retrospective Studies; Status Epilepticus; Treatment Outcome

2012
Use of single- and multi-drug regimens in the management of classic (idiopathic) trigeminal neuralgia: an 11-year experience at a single Sri Lankan institution.
    Journal of investigative and clinical dentistry, 2012, Volume: 3, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Pain Measurement; Phenytoin; Retrospective Studies; Sri Lanka; Treatment Outcome; Trigeminal Neuralgia; Valproic Acid

2012
Activity-dependent alternative splicing increases persistent sodium current and promotes seizure.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, May-23, Volume: 32, Issue:21

    Topics: Alternative Splicing; Animals; Drosophila Proteins; Exons; gamma-Aminobutyric Acid; Membrane Potentials; Molecular Sequence Data; Mutant Proteins; Phenytoin; Picrotoxin; Ribonucleoproteins; Seizures; Sodium Channels; Synaptic Transmission

2012
Antiepileptic drugs prevent changes in adenosine deamination during acute seizure episodes in adult zebrafish.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 104

    Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Gene Expression; Male; Pentylenetetrazole; Phenytoin; Seizures; Valproic Acid; Zebrafish

2013
Glia and epilepsy: experimental investigation of antiepileptic drugs in an astroglia/microglia co-culture model of inflammation.
    Epilepsia, 2014, Volume: 55, Issue:1

    Topics: Amines; Animals; Anticonvulsants; Astrocytes; Blotting, Western; Carbamazepine; Cells, Cultured; Coculture Techniques; Connexin 43; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Gap Junctions; Inflammation; Microglia; Neuroglia; Phenytoin; Rats; Rats, Wistar; Transforming Growth Factor beta1; Valproic Acid

2014
Anticonvulsant activity of pregabalin in the maximal electroshock-induced seizure assay in α2δ1 (R217A) and α2δ2 (R279A) mouse mutants.
    Epilepsy research, 2014, Volume: 108, Issue:5

    Topics: Animals; Anticonvulsants; Calcium Channels; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; gamma-Aminobutyric Acid; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Mutation, Missense; Phenytoin; Pregabalin; Seizures; Species Specificity; Time Factors

2014
Simultaneous analysis of 22 antiepileptic drugs in postmortem blood, serum and plasma using LC-MS-MS with a focus on their role in forensic cases.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:8

    Topics: Amines; Anticonvulsants; Carbamazepine; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Limit of Detection; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tiagabine; Topiramate; Triazines; Valproic Acid

2014
Cosmetic side effects of antiepileptic drugs in adults with epilepsy.
    Epilepsy & behavior : E&B, 2015, Volume: 42

    Topics: Acne Vulgaris; Adult; Alopecia; Anticonvulsants; Epilepsy; Female; gamma-Aminobutyric Acid; Gingival Diseases; Hirsutism; Humans; Levetiracetam; Male; Middle Aged; Phenytoin; Piracetam; Pregabalin; Risk Factors; Sex Factors; Valproic Acid; Weight Gain

2015
Calcium Imaging of Neuronal Activity in Drosophila Can Identify Anticonvulsive Compounds.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: 4-Aminopyridine; Adult; Amines; Animals; Anticonvulsants; Antipain; Calcium; Calmodulin; Central Nervous System; Convulsants; Cyclohexanecarboxylic Acids; Dipyridamole; Drosophila melanogaster; Drosophila Proteins; Female; Gabapentin; gamma-Aminobutyric Acid; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Larva; Male; Molecular Imaging; Motor Neurons; Phenytoin; Picrotoxin; Primary Cell Culture; Sodium Channels

2016
Comparative persistence of antiepileptic drugs in patients with epilepsy: A STROBE-compliant retrospective cohort study.
    Medicine, 2016, Volume: 95, Issue:35

    Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Lamotrigine; Male; Medication Adherence; Middle Aged; Oxcarbazepine; Phenytoin; Proportional Hazards Models; Retrospective Studies; Risk Factors; Taiwan; Topiramate; Triazines; Valproic Acid; Young Adult

2016
Antiepileptic drugs: Impacts on human serum paraoxonase-1.
    Journal of biochemical and molecular toxicology, 2017, Volume: 31, Issue:6

    Topics: Amines; Anticonvulsants; Aryldialkylphosphatase; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Kinetics; Levetiracetam; Phenytoin; Piracetam; Primidone; Turkey; Valproic Acid

2017
Effects of the Antiepileptic Drugs Phenytoin, Gabapentin, and Levetiracetam on Bone Strength, Bone Mass, and Bone Turnover in Rats.
    Biological & pharmaceutical bulletin, 2017, Volume: 40, Issue:11

    Topics: Administration, Oral; Amines; Animals; Anticonvulsants; Bone Density; Bone Remodeling; Bone Resorption; Cancellous Bone; Cyclohexanecarboxylic Acids; Epilepsy; Femur; Fractures, Bone; Gabapentin; gamma-Aminobutyric Acid; Humans; Levetiracetam; Male; Osteoclasts; Phenytoin; Piracetam; Rats; Rats, Sprague-Dawley; Tibia; Tomography, X-Ray Computed

2017
Hypothyroidism induced by phenytoin and gabapentin: A Case Report.
    Medicine, 2018, Volume: 97, Issue:43

    Topics: Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypothyroidism; Male; Phenytoin; Thyroxine

2018