gamendazole has been researched along with lonidamine* in 1 studies
1 other study(ies) available for gamendazole and lonidamine
| Article | Year |
|---|---|
The lonidamine derivative H2-gamendazole reduces cyst formation in polycystic kidney disease.
Autosomal dominant polycystic kidney disease (ADPKD) is a debilitating renal neoplastic disorder with limited treatment options. It is characterized by the formation of large fluid-filled cysts that develop from kidney tubules through abnormal cell proliferation and cyst-filling fluid secretion driven by cAMP-dependent Cl Topics: Actins; Animals; Carboxylic Acids; Cell Proliferation; Cells, Cultured; Colforsin; Cyclin-Dependent Kinase 4; Cystic Fibrosis Transmembrane Conductance Regulator; Cysts; EGF Family of Proteins; Heat-Shock Proteins; Humans; Indazoles; Kidney; Mice; Polycystic Kidney Diseases; Polycystic Kidney, Autosomal Dominant; Proto-Oncogene Proteins c-akt; Receptors, Cell Surface | 2022 |