gallamine triethiodide has been researched along with n-methylscopolamine in 52 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (32.69) | 18.7374 |
| 1990's | 17 (32.69) | 18.2507 |
| 2000's | 14 (26.92) | 29.6817 |
| 2010's | 4 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bernhardt, G; Gmeiner, P; Hübner, H; Keller, M; Pegoli, A; She, X; Wifling, D | 1 |
| el-Fakahany, EE; Hu, J; Lee, NH | 1 |
| Brann, MR; Ellis, J; Huyler, J | 1 |
| el-Fakahany, EE; Lee, NH | 3 |
| Delmendo, RE; Lopez, M; Michel, AD; Whiting, RL | 1 |
| Ellis, J; Hoss, W | 1 |
| Cross, AJ; Green, AR; Hunter, AJ; Jones, JA; Murray, TK | 1 |
| Delen, FM; Ehlert, FJ; Friedman, DJ; Self, DW; Yun, SH | 1 |
| Brown, DA; Marrion, NV; Marsh, SJ; Smart, TG | 1 |
| Ellis, J; Seidenberg, M | 2 |
| Ehlert, FJ | 1 |
| Christophe, J; De Neef, P; Robberecht, P; Waelbroeck, M | 1 |
| el-Fakahany, EE; Kim, ON; Lai, WS; Lee, NH; Surichamorn, W | 1 |
| Michel, AD; Whiting, RL | 1 |
| Christophe, J; Gillard, M; Waelbroeck, M | 1 |
| Aronstam, RS; Narayanan, TK | 1 |
| Ehlert, FJ; Jenden, DJ | 1 |
| Cortés, R; Palacios, JM | 1 |
| Ellis, J; Lenox, RH | 2 |
| Proska, J; Tucek, S | 1 |
| Christopoulos, A; Mitchelson, F | 1 |
| Brann, MR; Ellis, J; Seidenberg, M | 1 |
| Birdsall, NJ; Lazareno, S; Matsui, H | 1 |
| Eck, M; Leppik, RA; Miller, RC; Paquet, JL | 1 |
| Burgmer, U; Kostenis, E; Mohr, K; Tränkle, C | 1 |
| Ellis, J; Gnagey, A | 1 |
| Christopoulos, A; Lanzafame, A; Mitchelson, F; Ziegler, A | 1 |
| Christopoulos, A; Lanzafame, A; Mitchelson, F | 2 |
| Potter, LT; Purkerson, SL | 1 |
| Mohr, K; Schröter, A; Tränkle, C; Weyand, O | 1 |
| Franken, C; Mohr, K; Tränkle, C | 1 |
| Mohr, K; Schröter, A; Tränkle, C | 1 |
| Kostenis, E; Mohr, K; Tränkle, C | 1 |
| Krejcí, A; Tucek, S | 1 |
| Corsini, GU; Maggio, R; Novi, F; Scarselli, M | 1 |
| Antony, J; Grossmüller, M; Holzgrabe, U; Mohr, K; Tränkle, C | 1 |
| Ellis, J; Höltje, HD; Mohr, K; Prilla, S; Schrobang, J | 1 |
| Ellis, J; Huang, XP | 1 |
| Appadu, BL; Cembala, TM; Forde, SC; Lambert, DG | 1 |
| Ehlert, FJ; Griffin, MT | 1 |
| Avlani, VA; Christopoulos, A; McLoughlin, DJ; Sexton, PM | 1 |
| Pisterzi, LF; Redka, DS; Wells, JW | 1 |
| Ehlert, FJ; Figueroa, KW; Suga, H | 1 |
| Ehlert, FJ; Suga, H | 1 |
| Ellis, J; Huang, XP; Seidenberg, M; Shivnaraine, RV; Wells, JW | 1 |
| Birdsall, NJ; Lazareno, S | 1 |
| Bonnet, D; Daval, SB; Galzi, JL; Hibert, M; Ilien, B; Kellenberger, E; Valant, C | 1 |
1 review(s) available for gallamine triethiodide and n-methylscopolamine
| Article | Year |
|---|---|
Muscarinic receptor subtypes in the central nervous system.
Topics: Adenylyl Cyclases; Affinity Labels; Animals; Brain; Brain Chemistry; Copper; Disulfides; Gallamine Triethiodide; Guanosine Triphosphate; Guanylate Cyclase; Hormones; Ion Channels; Male; Metals; N-Methylscopolamine; Phosphatidylinositols; Phosphorylation; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Sulfhydryl Compounds | 1985 |
51 other study(ies) available for gallamine triethiodide and n-methylscopolamine
| Article | Year |
|---|---|
Radiolabeled Dibenzodiazepinone-Type Antagonists Give Evidence of Dualsteric Binding at the M
Topics: Benzodiazepinones; Binding Sites; Molecular Dynamics Simulation; Muscarinic Antagonists; Radioisotopes; Receptor, Muscarinic M2 | 2017 |
Modulation by certain conserved aspartate residues of the allosteric interaction of gallamine at the m1 muscarinic receptor.
Topics: Animals; Asparagine; Aspartic Acid; Cells, Cultured; Cricetinae; Cricetulus; Drug Residues; Female; Gallamine Triethiodide; N-Methylscopolamine; Ovary; Receptors, Muscarinic; Scopolamine Derivatives | 1992 |
Allosteric regulation of cloned m1-m5 muscarinic receptor subtypes.
Topics: Animals; Binding Sites; Cell Line; Gallamine Triethiodide; Humans; Kinetics; N-Methylscopolamine; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Tubocurarine; Verapamil | 1991 |
Allosteric interactions at the m1, m2 and m3 muscarinic receptor subtypes.
Topics: Allosteric Regulation; Animals; Cells, Cultured; Cricetinae; Gallamine Triethiodide; N-Methylscopolamine; Parasympatholytics; Pertussis Toxin; Phenethylamines; Potassium Channels; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Verapamil; Virulence Factors, Bordetella | 1991 |
The allosteric binding profile of himbacine: a comparison with other cardioselective muscarinic antagonists.
Topics: Alkaloids; Allosteric Regulation; Animals; Atropine; Binding, Competitive; Diamines; Dose-Response Relationship, Drug; Furans; Gallamine Triethiodide; Male; Myocardium; N-Methylscopolamine; Naphthalenes; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
On the interaction of gallamine with muscarinic receptor subtypes.
Topics: Animals; Binding, Competitive; Cells, Cultured; Chickens; Culture Techniques; Diamines; Female; Gallamine Triethiodide; Guinea Pigs; Heart; Humans; Kinetics; Membranes; Myocardium; N-Methylscopolamine; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
The cholinergic pharmacology of tetrahydroaminoacridine in vivo and in vitro.
Topics: Aminoacridines; Animals; Behavior, Animal; Brain Chemistry; Cholinesterase Inhibitors; Gallamine Triethiodide; In Vitro Techniques; Male; Mice; Myocardium; N-Methylscopolamine; Nicotine; Oxotremorine; Parasympathetic Nervous System; Physostigmine; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Tacrine | 1989 |
Coupling of subtypes of the muscarinic receptor to adenylate cyclase in the corpus striatum and heart.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Binding, Competitive; Corpus Striatum; Gallamine Triethiodide; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Pirenzepine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; RNA, Messenger; Scopolamine Derivatives | 1989 |
Muscarinic suppression of the M-current in the rat sympathetic ganglion is mediated by receptors of the M1-subtype.
Topics: Animals; Calcium; Gallamine Triethiodide; Ganglia, Spinal; Ganglia, Sympathetic; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Piperidines; Pirenzepine; Potassium Channels; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1989 |
Gallamine exerts biphasic allosteric effects at muscarinic receptors.
Topics: Allosteric Regulation; Animals; Gallamine Triethiodide; Male; N-Methylscopolamine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1989 |
Gallamine allosterically antagonizes muscarinic receptor-mediated inhibition of adenylate cyclase activity in the rat myocardium.
Topics: Adenylyl Cyclase Inhibitors; Algorithms; Animals; Dose-Response Relationship, Drug; Gallamine Triethiodide; Heart; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1988 |
Effects of d-tubocurarine on rat cardiac muscarinic receptors: a comparison with gallamine.
Topics: Animals; Binding, Competitive; Gallamine Triethiodide; Heart; In Vitro Techniques; Kinetics; Male; N-Methylscopolamine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Tubocurarine | 1988 |
Effects of aging on the interaction of quinuclidinyl benzilate, N-methylscopolamine, pirenzepine, and gallamine with brain muscarinic receptors.
Topics: Aging; Animals; Binding, Competitive; Cerebellum; Cerebral Cortex; Corpus Striatum; Gallamine Triethiodide; Hippocampus; In Vitro Techniques; Male; N-Methylscopolamine; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptors, Muscarinic; Scopolamine Derivatives | 1988 |
Influence of ligand choice on the apparent binding profile of gallamine to cardiac muscarinic receptors. Identification of three main types of gallamine-muscarinic receptor interactions.
Topics: Algorithms; Alkylation; Animals; Atropine; Binding Sites; Gallamine Triethiodide; Male; Myocardium; N-Methylscopolamine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1988 |
Direct binding studies on ileal and cardiac muscarinic receptors.
Topics: Animals; Gallamine Triethiodide; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Male; Membranes; Muscle, Smooth; Myocardium; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1987 |
Interactions between gallamine and muscarinic receptors: allosterism and subpopulation specificity are separate phenomena.
Topics: Animals; Brain Stem; Gallamine Triethiodide; In Vitro Techniques; Male; Molecular Conformation; N-Methylscopolamine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Verapamil | 1987 |
In vitro effects of gallamine on dissociation kinetics of (3H)N-methylscopolamine and (3H)pirenzepine from rat brain muscarinic receptors.
Topics: Animals; Atropine; Benzodiazepinones; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Gallamine Triethiodide; Hippocampus; Kinetics; Male; Myocardium; N-Methylscopolamine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Substrate Specificity | 1986 |
Allosteric effect of gallamine on muscarinic cholinergic receptor binding: influence of guanine nucleotides and conformational state.
Topics: Allosteric Regulation; Animals; Brain; Cell Membrane; Gallamine Triethiodide; Guanine Nucleotides; Kinetics; Male; N-Methylscopolamine; Protein Conformation; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1986 |
The binding of a 2-chloroethylamine derivative of oxotremorine (BM 123) to muscarinic receptors in the rat cerebral cortex.
Topics: Alkylation; Animals; Atropine; Benzodiazepinones; Binding Sites; Binding, Competitive; Cerebral Cortex; Gallamine Triethiodide; Kinetics; N-Methylscopolamine; Oxotremorine; Pirenzepine; Pyrrolidinones; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Thiosulfates | 1985 |
Muscarinic cholinergic receptor subtypes in the rat brain. I. Quantitative autoradiographic studies.
Topics: Animals; Autoradiography; Binding Sites; Brain; Classification; Gallamine Triethiodide; Kinetics; Male; Muscarine; N-Methylscopolamine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Tissue Distribution; Tritium | 1986 |
Quaternary forms of classical muscarinic antagonists distinguish subpopulations of muscarinic receptors: correlation with gallamine-defined subpopulations.
Topics: Allosteric Site; Animals; Atropine; Atropine Derivatives; Binding, Competitive; Brain; Gallamine Triethiodide; In Vitro Techniques; Male; N-Methylscopolamine; Parasympatholytics; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives | 1985 |
Characterization of the interactions of gallamine with muscarinic receptors from brain.
Topics: Animals; Brain; Gallamine Triethiodide; In Vitro Techniques; Male; N-Methylscopolamine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Tritium | 1985 |
Competition between positive and negative allosteric effectors on muscarinic receptors.
Topics: Alcuronium; Allosteric Site; Animals; Binding, Competitive; Gallamine Triethiodide; Kinetics; Mathematical Computing; Models, Biological; Myocardium; N-Methylscopolamine; Nicotinic Antagonists; Poisons; Radioligand Assay; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Strychnine; Tritium | 1995 |
[3H]N-methylscopolamine dissociation from muscarine receptors affected by low concentrations of allosteric modulators.
Topics: Allosteric Regulation; Animals; Atropine; Binding, Competitive; Gallamine Triethiodide; Guinea Pigs; In Vitro Techniques; Kinetics; Ligands; Muscarinic Antagonists; N-Methylscopolamine; Nicotinic Antagonists; Parasympatholytics; Receptors, Muscarinic; Scopolamine Derivatives | 1995 |
Use of chimeric muscarinic receptors to investigate epitopes involved in allosteric interactions.
Topics: Allosteric Site; Animals; Cell Line; Epitopes; Gallamine Triethiodide; Humans; In Vitro Techniques; N-Methylscopolamine; Rats; Receptors, Muscarinic; Recombinant Fusion Proteins; Scopolamine Derivatives | 1993 |
Probing of the location of the allosteric site on m1 muscarinic receptors by site-directed mutagenesis.
Topics: Acetylcholine; Alanine; Allosteric Regulation; Animals; Base Sequence; Binding Sites; Binding, Competitive; Gallamine Triethiodide; Kinetics; Molecular Sequence Data; Muscarinic Antagonists; Mutagenesis, Site-Directed; Mutation; N-Methylscopolamine; Receptors, Muscarinic; Scopolamine Derivatives; Tritium; Tryptophan | 1995 |
Role of acidic amino acids in the allosteric modulation by gallamine of antagonist binding at the m2 muscarinic acetylcholine receptor.
Topics: Allosteric Regulation; Amino Acid Sequence; Amino Acids; Animals; Base Sequence; Binding Sites; Cells, Cultured; Gallamine Triethiodide; Hydrogen-Ion Concentration; Mice; Molecular Sequence Data; Muscarinic Antagonists; Mutagenesis, Site-Directed; N-Methylscopolamine; Oligodeoxyribonucleotides; Receptors, Muscarinic; Scopolamine Derivatives | 1994 |
Search for lead structures to develop new allosteric modulators of muscarinic receptors.
Topics: Alcuronium; Allosteric Regulation; Animals; Dose-Response Relationship, Drug; Gallamine Triethiodide; N-Methylscopolamine; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Swine | 1996 |
Allosteric regulation of the binding of [3H]acetylcholine to m2 muscarinic receptors.
Topics: Acetylcholine; Acetylcholinesterase; Allosteric Regulation; Animals; Cell Membrane; CHO Cells; Cricetinae; Gallamine Triethiodide; Gallic Acid; N-Methylscopolamine; Receptors, Muscarinic; Scopolamine Derivatives | 1996 |
Kinetic studies of co-operativity at atrial muscarinic M2 receptors with an "infinite dilution" procedure.
Topics: Allosteric Regulation; Animals; Female; Gallamine Triethiodide; Guinea Pigs; Heart Atria; Kinetics; Male; Muscarinic Antagonists; N-Methylscopolamine; Receptor, Muscarinic M2; Receptors, Muscarinic; Scopolamine Derivatives | 1997 |
Three allosteric modulators act at a common site, distinct from that of competitive antagonists, at muscarinic acetylcholine M2 receptors.
Topics: Alcuronium; Allosteric Regulation; Animals; Atropine; Female; Gallamine Triethiodide; Guinea Pigs; Male; Muscarinic Antagonists; N-Methylscopolamine; Receptor, Muscarinic M2; Receptors, Muscarinic; Scopolamine Derivatives | 1997 |
Use of antimuscarinic toxins to facilitate studies of striatal m4 muscarinic receptors.
Topics: Alkaloids; Animals; Benzodiazepines; Binding, Competitive; Cats; CHO Cells; Corpus Striatum; Cricetinae; Elapid Venoms; Furans; Gallamine Triethiodide; Humans; Male; Muscarinic Antagonists; N-Methylscopolamine; Naphthalenes; Neurotoxins; Piperidines; Pirenzepine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptor, Muscarinic M4; Receptors, Muscarinic; Recombinant Proteins | 1998 |
Using a radioalloster to test predictions of the cooperativity model for gallamine binding to the allosteric site of muscarinic acetylcholine M(2) receptors.
Topics: Allosteric Site; Animals; Binding, Competitive; Drug Interactions; Gallamine Triethiodide; In Vitro Techniques; Isoindoles; Models, Biological; Myocardium; N-Methylscopolamine; Nicotinic Antagonists; Phthalimides; Receptor, Muscarinic M2; Receptors, Muscarinic; Swine | 1999 |
Testing the specificity of allosteric modulators of muscarinic receptors in phylogenetically closely related histamine H1-receptors.
Topics: Alcuronium; Allosteric Regulation; Animals; Binding Sites; Gallamine Triethiodide; Guinea Pigs; Isoindoles; N-Methylscopolamine; Phthalimides; Pyrilamine; Receptors, Histamine H1; Receptors, Muscarinic | 2000 |
Modes of allosteric interactions with free and [3H]N-methylscopolamine-occupied muscarinic M2 receptors as deduced from buffer-dependent potency shifts.
Topics: Alcuronium; Animals; Binding Sites; Binding, Competitive; Buffers; Cholinergic Agents; Dose-Response Relationship, Drug; Gallamine Triethiodide; Kinetics; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Nicotinic Agonists; Pyridinium Compounds; Receptor, Muscarinic M2; Receptors, Muscarinic; Swine; Tritium | 2000 |
The allosteric interaction of otenzepad (AF-DX 116) at muscarinic M2 receptors in guinea pig atria.
Topics: Acetylcholine; Allosteric Regulation; Animals; Atropine; Carbachol; Cardiotonic Agents; Dexetimide; Electric Stimulation; Female; Gallamine Triethiodide; Guinea Pigs; Heart Atria; In Vitro Techniques; Kinetics; Male; Muscarinic Antagonists; N-Methylscopolamine; Nicotinic Antagonists; Parasympatholytics; Phthalimides; Pirenzepine; Quaternary Ammonium Compounds; Radioligand Assay; Receptor, Muscarinic M2; Receptors, Muscarinic | 2001 |
Muscarinic allosteric modulation: M2/M3 subtype selectivity of gallamine is independent of G-protein coupling specificity.
Topics: Allosteric Regulation; Animals; Cell Line; Dose-Response Relationship, Drug; Gallamine Triethiodide; GTP-Binding Proteins; Humans; N-Methylscopolamine; Neuromuscular Nondepolarizing Agents; Parasympatholytics; Rats; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic | 2001 |
Changes of cooperativity between N-methylscopolamine and allosteric modulators alcuronium and gallamine induced by mutations of external loops of muscarinic M(3) receptors.
Topics: Alcuronium; Allosteric Regulation; Amino Acid Sequence; Arginine; Binding Sites; Gallamine Triethiodide; Glycine; Humans; Molecular Sequence Data; Mutation; N-Methylscopolamine; Nicotinic Antagonists; Parasympatholytics; Protein Conformation; Radioligand Assay; Receptor, Muscarinic M3; Receptors, Muscarinic; Sequence Homology, Amino Acid; Tritium | 2001 |
An unusual form of the association binding kinetics of N-[3H]methylscopolamine to the split muscarinic M2trunk/M2tail receptor.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cells, Cultured; Chlorocebus aethiops; COS Cells; Gallamine Triethiodide; Guanosine 5'-O-(3-Thiotriphosphate); Indicators and Reagents; Kinetics; Muscarinic Antagonists; N-Methylscopolamine; Nicotinic Antagonists; Parasympatholytics; Peptide Fragments; Plasmids; Quinuclidinyl Benzilate; Receptor, Muscarinic M2; Receptors, Muscarinic | 2003 |
Allosteric site in M2 acetylcholine receptors: evidence for a major conformational change upon binding of an orthosteric agonist instead of an antagonist.
Topics: Allosteric Regulation; Allosteric Site; Animals; Binding, Competitive; Gallamine Triethiodide; In Vitro Techniques; Isoindoles; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Obidoxime Chloride; Oxotremorine; Phthalimides; Protein Conformation; Pyridinium Compounds; Receptor, Muscarinic M2; Swine | 2006 |
Allosteric interactions with muscarinic acetylcholine receptors: complex role of the conserved tryptophan M2422Trp in a critical cluster of amino acids for baseline affinity, subtype selectivity, and cooperativity.
Topics: Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Binding Sites; Binding, Competitive; Gallamine Triethiodide; Humans; Isoindoles; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutant Proteins; Mutation; N-Methylscopolamine; Phthalimides; Receptors, Muscarinic; Threonine; Tryptophan | 2006 |
Mutational disruption of a conserved disulfide bond in muscarinic acetylcholine receptors attenuates positive homotropic cooperativity between multiple allosteric sites and has subtype-dependent effects on the affinities of muscarinic allosteric ligands.
Topics: Allosteric Site; Amino Acid Sequence; Base Sequence; Disulfides; Gallamine Triethiodide; Isoindoles; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylscopolamine; Phthalimides; Receptors, Muscarinic; Structure-Activity Relationship; Tacrine | 2007 |
Allosteric interaction of the neuromuscular blockers vecuronium and pancuronium with recombinant human muscarinic M2 receptors.
Topics: Allosteric Regulation; Animals; Atropine; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Gallamine Triethiodide; Humans; Kinetics; Muscarinic Antagonists; N-Methylscopolamine; Neuromuscular Blocking Agents; Pancuronium; Radioligand Assay; Receptor, Muscarinic M2; Recombinant Proteins; Tritium; Vecuronium Bromide | 2007 |
Two-state models and the analysis of the allosteric effect of gallamine at the M2 muscarinic receptor.
Topics: Allosteric Regulation; Animals; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Gallamine Triethiodide; Humans; Models, Biological; Muscarinic Agonists; N-Methylscopolamine; Receptor, Muscarinic M2 | 2008 |
The impact of orthosteric radioligand depletion on the quantification of allosteric modulator interactions.
Topics: Alcuronium; Allosteric Regulation; Animals; Atropine; Carbachol; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Gallamine Triethiodide; Ligands; Models, Biological; N-Methylscopolamine; Radioligand Assay; Receptor, Muscarinic M2; Tritium | 2008 |
Binding of orthosteric ligands to the allosteric site of the M(2) muscarinic cholinergic receptor.
Topics: Allosteric Regulation; Allosteric Site; Animals; Binding, Competitive; Cell Line; Gallamine Triethiodide; Humans; Insecta; Kinetics; Ligands; N-Methylscopolamine; Obidoxime Chloride; Protein Structure, Quaternary; Receptor, Muscarinic M2; Solubility | 2008 |
Use of acetylcholine mustard to study allosteric interactions at the M(2) muscarinic receptor.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkylation; Allosteric Regulation; Androstanes; Animals; Benzimidazoles; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Gallamine Triethiodide; Humans; N-Methylscopolamine; Receptor, Muscarinic M2 | 2008 |
Investigating the interaction of McN-A-343 with the M2 muscarinic receptor using its nitrogen mustard derivative.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkylation; Alkynes; Androstanes; Animals; Benzimidazoles; Carbamates; CHO Cells; Cricetinae; Cricetulus; Gallamine Triethiodide; Male; N-Methylscopolamine; Nitrogen Mustard Compounds; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2 | 2010 |
Heterotropic cooperativity within and between protomers of an oligomeric M(2) muscarinic receptor.
Topics: Allosteric Regulation; Allosteric Site; Animals; CHO Cells; Cholinergic Antagonists; Cricetinae; Gallamine Triethiodide; Kinetics; Muscarinic Antagonists; N-Methylscopolamine; Protein Subunits; Quinuclidinyl Benzilate; Receptor, Muscarinic M2; Sf9 Cells; Solubility; Swine | 2012 |
Detection, quantitation, and verification of allosteric interactions of agents with labeled and unlabeled ligands at G protein-coupled receptors: interactions of strychnine and acetylcholine at muscarinic receptors.
Topics: Acetylcholine; Allosteric Regulation; Animals; CHO Cells; Cloning, Molecular; Cricetinae; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Radioligand Assay; Receptors, Muscarinic; Strychnine | 1995 |
Fluorescent derivatives of AC-42 to probe bitopic orthosteric/allosteric binding mechanisms on muscarinic M1 receptors.
Topics: Allosteric Regulation; Calcium; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Green Fluorescent Proteins; HEK293 Cells; Humans; Models, Molecular; Molecular Probes; Piperidines; Radioligand Assay; Receptor, Muscarinic M1; Recombinant Fusion Proteins; Rhodamines; Solubility; Structure-Activity Relationship | 2012 |