galactose has been researched along with tolrestat in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (48.00) | 18.7374 |
| 1990's | 12 (48.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bauman, JG; Dietrich, A; Gorham, BJ; Harrison, MC; Jones, LR; Kelly, JM; Malamas, M; Millen, J; Sredy, J; Wrobel, J | 1 |
| Kinoshita, JH; Laver, N; Robison, WG; Tillis, TN | 1 |
| Capogreco, C; Fisher, E; Heffernan, S; McLennan, S; Ross, GR; Turtle, JR; Yue, DK | 1 |
| Aynedjian, HS; Bank, N; Coco, M | 1 |
| Hohman, TC; Kinoshita, JH; Laver, N; Nagata, M; Robison, WG | 1 |
| Kinoshita, JH; Laver, N; Nagata, M; Robison, WG; Tillis, TN | 1 |
| Akagi, Y; Dvornik, D; Gonzalez, R; Kador, PF; Kinoshita, JH; Robison, WG | 1 |
| Kador, PF; Kinoshita, JH; Robison, WG | 1 |
| Ackermann, KE; Berger, RA; Chang, K; Cicero, TJ; Jeffrey, JR; Kilo, C; Sherman, WR; Tilton, RG; Tomlinson, M; Williamson, JR | 1 |
| Nagata, M; Robison, WG | 1 |
| Kinoshita, JH; Nagata, M; Robison, WG | 1 |
| Akagi, Y; Kador, PF; Kinoshita, JH; Terubayashi, H | 1 |
| Kador, PF; Kinoshita, JH; Sharpless, NE | 1 |
| Dvornik, D; Gonzalez, R; Greselin, E; Simard-Duquesne, N | 1 |
| Calcutt, NA; Malmberg, AB; Yaksh, TL; Yamamoto, T | 1 |
| Bache, M; Calcutt, NA; McMurray, HF; Mizisin, AP; Moorhouse, DF; Parthasarathy, S; Powell, HC | 1 |
| Chatzilias, AA; Whiteside, CI | 1 |
| Cunnick, J; Gonzalez, K; Takemoto, DJ; Udovichenko, I | 1 |
| Lou, MF; Xu, GT; York, B; Zigler, S | 1 |
| Epstein, M; Forster, HG; Hohman, TC; ter Wee, PM | 1 |
| Brett, FM; Calcutt, NA; Kalichman, MW; Mizisin, AP | 1 |
| Burgan, J; Faller, A; Obrosova, I; Ostrow, E; Williamson, JR | 1 |
| Chang, K; Ido, Y; LeJeune, W; Monafo, WW; Tilton, RG; Williamson, JR | 1 |
| Banditelli, S; Boldrini, E; Cappiello, M; Cecconi, I; Dal Monte, M; Del Corso, A; Marini, I; Mura, U; Vilardo, PG | 1 |
| Kador, PF; Zhang, P; Zhang, Z | 1 |
1 review(s) available for galactose and tolrestat
| Article | Year |
|---|---|
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.
Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Models, Animal; Fluorenes; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Models, Molecular; Naphthalenes; Phthalazines; Rhodanine; Sorbitol; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases; Thiazolidines; Tissue Distribution | 1985 |
24 other study(ies) available for galactose and tolrestat
| Article | Year |
|---|---|
Syntheses of tolrestat analogues containing additional substituents in the ring and their evaluation as aldose reductase inhibitors. Identification of potent, orally active 2-fluoro derivatives.
Topics: Administration, Oral; Aldehyde Reductase; Animals; Cattle; Chemical Phenomena; Chemistry; Diabetes Mellitus, Experimental; Diaphragm; Galactitol; Galactose; Glycine; Lens, Crystalline; Male; Molecular Structure; Naphthalenes; Prodrugs; Rats; Rats, Inbred Strains; Sciatic Nerve | 1991 |
Diabetes-related histopathologies of the rat retina prevented with an aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Basement Membrane; Capillaries; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Female; Galactose; Microscopy, Electron; Naphthalenes; Rats; Rats, Inbred Strains; Retina; Retinal Vessels; Sugar Alcohol Dehydrogenases | 1990 |
Ascorbic acid metabolism and polyol pathway in diabetes.
Topics: Aldehyde Reductase; Animals; Ascorbic Acid; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Female; Galactose; Inositol; Kidney Cortex; Kidney Medulla; Naphthalenes; Rats; Rats, Inbred Strains; Reference Values; Sorbitol | 1989 |
Galactose feeding causes glomerular hyperperfusion: prevention by aldose reductase inhibition.
Topics: Aldehyde Reductase; Animals; Galactose; Glomerular Filtration Rate; Imidazoles; Imidazolidines; Kidney Glomerulus; Male; Mathematics; Models, Theoretical; Naphthalenes; Nephrons; Rats; Rats, Inbred Strains; Reference Values; Sugar Alcohol Dehydrogenases | 1989 |
Diabetic-like retinopathy in rats prevented with an aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Basement Membrane; Blood Glucose; Diabetic Retinopathy; Disease Models, Animal; Female; Galactose; Naphthalenes; Polymers; Random Allocation; Rats; Rats, Inbred Strains; Retinal Vessels; Sugar Alcohol Dehydrogenases | 1989 |
Aldose reductase and pericyte-endothelial cell contacts in retina and optic nerve.
Topics: Aldehyde Reductase; Animals; Basement Membrane; Capillaries; Diabetic Retinopathy; Disease Models, Animal; Endothelium, Vascular; Female; Galactose; Intercellular Junctions; Naphthalenes; Optic Nerve; Rats; Rats, Inbred Strains; Retina; Retinal Vessels; Sugar Alcohol Dehydrogenases | 1989 |
Prevention of basement membrane thickening in retinal capillaries by a novel inhibitor of aldose reductase, tolrestat.
Topics: Aldehyde Reductase; Animals; Basement Membrane; Capillaries; Cataract; Diabetic Retinopathy; Galactose; Male; Microscopy, Electron; Naphthalenes; Rats; Rats, Inbred Strains; Retinal Vessels; Sugar Alcohol Dehydrogenases | 1986 |
The polyol pathway in retinal microangiopathy.
Topics: Aldehyde Reductase; Animals; Diabetic Retinopathy; Galactose; Imidazoles; Imidazolidines; Male; Naphthalenes; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases; Sugar Alcohols | 1986 |
Galactose ingestion increases vascular permeability and collagen solubility in normal male rats.
Topics: Aldehyde Reductase; Animals; Body Weight; Capillary Permeability; Collagen; Galactose; Imidazoles; Imidazolidines; Male; Naphthalenes; Organ Size; Prostate; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Solubility; Testosterone; Tissue Distribution | 1987 |
Aldose reductase, diabetes, and thickening of the retinal inner limiting membrane.
Topics: Aldehyde Reductase; Animals; Basement Membrane; Diabetes Mellitus; Galactose; Male; Naphthalenes; Rats; Rats, Inbred Strains; Retina; Sugar Alcohol Dehydrogenases | 1987 |
Aldose reductase and retinal capillary basement membrane thickening.
Topics: Aldehyde Reductase; Animals; Basement Membrane; Capillaries; Diabetic Retinopathy; Dietary Carbohydrates; Galactose; Male; Naphthalenes; Rats; Rats, Inbred Strains; Retinal Vessels; Sugar Alcohol Dehydrogenases | 1988 |
[Diabetic changes in pupillary reactions and iris histology. No. 3. The role of aldose reductase inhibitor to iridal vessel hyperpermeability of galactose-fed rats].
Topics: Aldehyde Reductase; Animals; Capillary Permeability; Diabetes Mellitus, Experimental; Galactose; Horseradish Peroxidase; Imidazoles; Imidazolidines; Iris; Male; Naphthalenes; Rats; Rats, Inbred Strains; Reflex, Pupillary; Sugar Alcohol Dehydrogenases | 1988 |
Prevention of cataract development in severely galactosemic rats by the aldose reductase inhibitor, tolrestat.
Topics: Animals; Cataract; Dose-Response Relationship, Drug; Galactitol; Galactose; Galactosemias; Humans; Lens, Crystalline; Male; Naphthalenes; Rats | 1985 |
Tolrestat treatment prevents modification of the formalin test model of prolonged pain in hyperglycemic rats.
Topics: Aldehyde Reductase; Animals; Behavior, Animal; Body Weight; Diabetes Mellitus, Experimental; Female; Formaldehyde; Galactose; Hyperalgesia; Hyperglycemia; Naphthalenes; Neural Pathways; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Sorbitol | 1994 |
Inhibition of macrophage chemotaxis and peripheral nerve regeneration in normal and hyperglycemic rats by the aldose reductase inhibitor Tolrestat.
Topics: Aldehyde Reductase; Animals; Chemotaxis; Female; Galactose; Hyperglycemia; Macrophages; Naphthalenes; Nerve Crush; Nerve Regeneration; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Reference Values; Sciatic Nerve | 1994 |
Cellular mechanisms of glucose-induced myo-inositol transport upregulation in rat mesangial cells.
Topics: Aldehyde Reductase; Animals; Biological Transport; Galactose; Glomerular Mesangium; Glucose; In Vitro Techniques; Inositol; Intracellular Membranes; Kinetics; Male; Naphthalenes; Rats; Rats, Sprague-Dawley; Sorbitol; Time Factors; Up-Regulation | 1994 |
Protein kinase C in galactosemic and tolrestat-treated lens epithelial cells.
Topics: Aldehyde Reductase; Amino Acid Sequence; Animals; Blotting, Western; Cataract; Cattle; Cells, Cultured; Culture Media; Epithelium; Galactose; Isoenzymes; Lens, Crystalline; Molecular Sequence Data; Naphthalenes; Peptides; Protein Kinase C | 1993 |
Inhibition of naphthalene cataract in rats by aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Cataract; Culture Techniques; Disease Models, Animal; Enzyme Inhibitors; Fluorenes; Galactose; Hydantoins; Imidazoles; Imidazolidines; Male; Naphthalenes; Rats; Spiro Compounds | 1996 |
Impairment of afferent arteriolar myogenic responsiveness in the galactose-fed rat is prevented by tolrestat.
Topics: Aldehyde Reductase; Angiotensin II; Animals; Arterioles; Blood Pressure; Cohort Studies; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet; Disease Models, Animal; Enzyme Inhibitors; Galactitol; Galactose; Image Processing, Computer-Assisted; In Vitro Techniques; Kidney; Male; Muscle, Smooth, Vascular; Naphthalenes; Perfusion; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents | 1996 |
Effects of seven days of galactose feeding and aldose reductase inhibition on mast cells and vessel morphometry in rat sciatic nerve.
Topics: Aldehyde Reductase; Animals; Blood Vessels; Body Weight; Cell Count; Cell Degranulation; Enzyme Inhibitors; Female; Galactose; Mast Cells; Microscopy, Electron; Naphthalenes; Polymers; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Time Factors; Vasoconstriction; Water | 1996 |
Glycolytic pathway, redox state of NAD(P)-couples and energy metabolism in lens in galactose-fed rats: effect of an aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Energy Metabolism; Enzyme Inhibitors; Galactitol; Galactose; Galactosemias; Gas Chromatography-Mass Spectrometry; Glycolysis; Inositol; Lens, Crystalline; Male; NADP; Naphthalenes; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1997 |
Diabetes impairs sciatic nerve hyperemia induced by surgical trauma: implications for diabetic neuropathy.
Topics: Aldehyde Reductase; Animals; Desipramine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Enzyme Inhibitors; Gadolinium; Galactose; Hemodynamics; Hyperemia; Inflammation; Laser-Doppler Flowmetry; Male; Microspheres; Naphthalenes; Neurosurgery; Polarography; Radioisotopes; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sciatic Nerve; Time Factors; Tritium; Wounds and Injuries | 1997 |
A new approach against sugar cataract through aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Enzyme Inhibitors; Galactitol; Galactose; Lens, Crystalline; Naphthalenes; Rats; Rats, Sprague-Dawley | 1999 |
Polyol effects on growth factors and MAPK signaling in rat retinal capillary cells.
Topics: Aldehyde Reductase; Animals; Capillaries; Cell Line; Endothelial Cells; Fluorenes; Galactitol; Galactose; Glucose; Hydantoins; Intercellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Naphthalenes; Pericytes; Rats; Rats, Transgenic; Retinal Vessels; Sorbitol | 2014 |