Compounds > galactose
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galactose and sorbinil

galactose has been researched along with sorbinil in 56 studies

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199030 (53.57)18.7374
1990's24 (42.86)18.2507
2000's1 (1.79)29.6817
2010's1 (1.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fukushi, S; Kador, P; Kinoshita, JH; Merola, LO1
Aldinger, CE; MacDonald, DP; Peterson, MJ; Sarges, R1
Johnson, MJ; Tsui, JY; Unakar, NJ1
Cammarata, PR; Tse, D; Yorio, T2
Kador, PF; Sato, S; Takahashi, Y; Wyman, M2
Giblin, FJ; Kador, PF; Kinoshita, JH; Lin, LR; Reddy, VN1
Das, A; Frank, RN; Samadani, E; Zhang, NL1
Chang, K; Kilo, C; Province, MA; Pugliese, G; Speedy, A; Tilton, RG; Williamson, JR1
Akagi, Y; Kador, PF1
Akagi, Y; Ikebe, H; Kador, PF; Kinoshita, JH; Takahashi, Y; Wyman, M1
Datiles, MB; Kador, PF; Kashima, K; Kinoshita, JH; Sinha, A1
Das, A; Frank, RN; Zhang, NL1
Plurad, SB; Schmidt, RE; Sherman, WR; Tilton, RG; Williamson, JR1
Aynedjian, HS; Bank, N; Coco, M1
Drea, CM; Hohman, TC; Nagata, M; Nishimura, C; Oliver, C; Robison, WG1
Eaton, RP; Frey, HJ; Jackson, JE; Scavini, M; Zager, PG1
Cammarata, PR; Jackson, T; Lou, M; Yorio, T1
Johnson, M; Tsui, J; Unakar, N1
Dunlap, JA; Leeney, EM; Yorek, MA1
Cheng, HM; Kawaba, T; Kinoshita, JH1
Eaton, RP; Gasparovic, C; Griffey, RH; Sibbitt, W1
Frank, RN1
Chan, LS; Khatami, M; Li, W; Rockey, JH1
Kador, PF; Kinoshita, JH; Robison, WG1
Ackermann, KE; Berger, RA; Chang, K; Cicero, TJ; Jeffrey, JR; Kilo, C; Sherman, WR; Tilton, RG; Tomlinson, M; Williamson, JR1
Cammarata, PR; Jackson, T; Yorio, T1
Akagi, Y; Kador, PF; Kinoshita, JH; Terubayashi, H1
Akagi, Y; Ikebe, H; Kador, PF; Kinoshita, JH; Terubayashi, H1
Chang, K; Eades, D; Kilo, C; Sherman, WR; Tilton, RG; Weigel, C; Williamson, JR1
Harries, W; Tsui, J; Unakar, NJ2
Kador, PF; Kinoshita, JH; Sharpless, NE1
Beyer-Mears, A; Cruz, E; Varagiannis, E1
Beyer-Mears, A; Cruz, E; Kelly, K1
Frank, RN; Keirn, GV; Keirn, RJ; Khoury, JK; Mancini, MA1
Tsui, JY; Unakar, NJ1
Kador, PF; Kinoshita, JH1
Frank, KW; Frank, RN; Keirn, RJ; Kennedy, A1
Datiles, M; Fukui, H; Kinoshita, JH; Kuwabara, T1
Bunn, HF; Chiou, SH; Chylack, LT; Kinoshita, JH1
Edmands, SD; Hughs, KS; Lee, SY; Meyer, SD; Saari, E; Yancey, PH1
Glover, JP; Jacot, JL; Laver, NM; Robison, WG1
Dorin, RI; Kaplan, DL; Shah, VO; Vela, BS; Zager, PG1
Engerman, RL; Kern, TS1
Anthony, P; Johnson, M; Tsui, J; Unakar, NJ1
Cammarata, PR; Chen, HQ1
Monnier, VM; Nagaraj, RH; Ortwerth, BJ; Prabhakaram, M1
Augustin, W; Kador, PF; Takahashi, Y; Wyman, M1
Lou, MF; Xu, GT; York, B; Zigler, S1
Cheng, HM; Hirose, S; Hirose, T; Igarashi, H; Xiong, J1
Beyer-Mears, A; Cruz, E; Diecke, FP; Mistry, K1
Cammarata, PR; Chen, SW; Guo, Z; Reeves, RE; Schafer, G1
Gerbitz, KD; Olgemöller, B; Schleicher, ED; Schwaabe, S1
Balestri, F; Buggiani, I; Cappiello, M; Del-Corso, A; Moschini, R; Mura, U; Pelosi, P; Rotondo, R1

Reviews

3 review(s) available for galactose and sorbinil

ArticleYear
Aldose reductase in diabetic complications of the eye.
    Metabolism: clinical and experimental, 1979, Volume: 28, Issue:4 Suppl 1

    Topics: Aldehyde Reductase; Animals; Cataract; Cattle; Chromans; Cornea; Diabetes Complications; Diabetic Retinopathy; Epithelium; Eye Diseases; Female; Galactitol; Galactose; Humans; Imidazoles; Imidazolidines; Lens, Crystalline; Mice; Mice, Obese; NADP; Polymers; Pregnancy; Rats; Regeneration; Retina; Rodentia; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases; Xylitol

1979
Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:7

    Topics: Aldehyde Reductase; Animals; Binding Sites; Blood Glucose; Cataract; Chemical Phenomena; Chemistry; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Models, Animal; Fluorenes; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Models, Molecular; Naphthalenes; Phthalazines; Rhodanine; Sorbitol; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases; Thiazolidines; Tissue Distribution

1985
Diabetic and galactosaemic cataracts.
    Ciba Foundation symposium, 1984, Volume: 106

    Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Galactose; Galactosemias; Glucose; Humans; Imidazoles; Imidazolidines; Intracellular Fluid; Lens, Crystalline; Mice; Osmosis; Rats; Sugar Alcohols

1984

Other Studies

53 other study(ies) available for galactose and sorbinil

ArticleYear
CP-45,634: a novel aldose reductase inhibitor that inhibits polyol pathway activity in diabetic and galactosemic rats.
    Metabolism: clinical and experimental, 1979, Volume: 28, Issue:4 Suppl 1

    Topics: Aldehyde Reductase; Animals; Benzopyrans; Cataract; Chromans; Diabetes Mellitus, Experimental; Galactitol; Galactose; Galactosemias; Imidazoles; Imidazolidines; Kinetics; Lens, Crystalline; Male; Polymers; Rats; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases

1979
Effect of aldose reductase inhibitors on lenticular dulcitol level in galactose fed rats.
    Journal of ocular pharmacology, 1992,Fall, Volume: 8, Issue:3

    Topics: Aldehyde Reductase; Animals; Cataract; Dietary Carbohydrates; Galactitol; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Rats; Rats, Sprague-Dawley

1992
Uncoupling of attenuated myo-[3H]inositol uptake and dysfunction in Na(+)-K(+)-ATPase pumping activity in hypergalactosemic cultured bovine lens epithelial cells.
    Diabetes, 1991, Volume: 40, Issue:6

    Topics: Aldehyde Reductase; Animals; Biological Transport, Active; Cattle; Diabetic Retinopathy; Epithelium; Galactose; Imidazoles; Imidazolidines; In Vitro Techniques; Inositol; Kinetics; Lens, Crystalline; Models, Biological; Rubidium; Sodium-Potassium-Exchanging ATPase; Tritium

1991
Progression of sugar cataract in the dog.
    Investigative ophthalmology & visual science, 1991, Volume: 32, Issue:6

    Topics: Aldehyde Reductase; Animals; Cataract; Dietary Carbohydrates; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Galactose; Humans; Imidazoles; Imidazolidines; Lens, Crystalline; Photography; Random Allocation; Rats; Rats, Inbred Strains

1991
Polyol accumulation in cultured human lens epithelial cells.
    Experimental eye research, 1991, Volume: 52, Issue:1

    Topics: Aldehyde Reductase; Cells, Cultured; Epithelial Cells; Epithelium; Fluorenes; Galactitol; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Inositol; Lens, Crystalline; Microscopy, Electron; Microscopy, Phase-Contrast; Polymers; Reference Values; Stereoisomerism; Vacuoles

1991
Increases in collagen type IV and laminin in galactose-induced retinal capillary basement membrane thickening--prevention by an aldose reductase inhibitor.
    Experimental eye research, 1990, Volume: 50, Issue:3

    Topics: Aldehyde Reductase; Animals; Basement Membrane; Capillaries; Collagen; Diabetic Retinopathy; Galactose; Galactosemias; Imidazoles; Imidazolidines; Laminin; Rats; Rats, Inbred WKY; Retinal Vessels; Sugar Alcohol Dehydrogenases

1990
Vascular filtration function in galactose-fed versus diabetic rats: the role of polyol pathway activity.
    Metabolism: clinical and experimental, 1990, Volume: 39, Issue:7

    Topics: Animals; Aorta; Blood Vessels; Cobalt Radioisotopes; Diabetes Mellitus, Experimental; Edetic Acid; Eye; Galactose; Galactosemias; Glomerular Filtration Rate; Hemodynamics; Imidazoles; Imidazolidines; Immunoglobulin G; Iodine Radioisotopes; Kidney; Male; Metabolic Clearance Rate; Polymers; Rats; Rats, Inbred Strains; Sciatic Nerve; Serum Albumin, Bovine

1990
Effect of aldose reductase inhibitors on the progression of retinopathy in galactose-fed dogs.
    Experimental eye research, 1990, Volume: 50, Issue:6

    Topics: Aldehyde Reductase; Animals; Diabetic Retinopathy; Dietary Carbohydrates; Dogs; Galactose; Imidazoles; Imidazolidines; Retinal Vessels; Sugar Alcohol Dehydrogenases

1990
Prevention of retinal vessel changes associated with diabetic retinopathy in galactose-fed dogs by aldose reductase inhibitors.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1990, Volume: 108, Issue:9

    Topics: Aldehyde Reductase; Aneurysm; Animals; Capillaries; Diabetic Retinopathy; Dogs; Dose-Response Relationship, Drug; Female; Galactitol; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Male; Retinal Vessels; Sugar Alcohol Dehydrogenases

1990
The effects of sorbinil, an aldose reductase inhibitor, on the corneal endothelium in galactosemic dogs.
    Investigative ophthalmology & visual science, 1990, Volume: 31, Issue:11

    Topics: Aldehyde Reductase; Animals; Cell Count; Dogs; Endothelium, Corneal; Galactose; Galactosemias; Image Processing, Computer-Assisted; Imidazoles; Imidazolidines; Male; Random Allocation

1990
Sorbinil does not prevent galactose-induced glomerular capillary basement membrane thickening in the rat.
    Diabetologia, 1990, Volume: 33, Issue:9

    Topics: Aldehyde Reductase; Animals; Basement Membrane; Capillaries; Collagen; Female; Galactose; Imidazoles; Imidazolidines; Kidney Glomerulus; Microscopy, Immunoelectron; Rats; Rats, Inbred WKY

1990
Sorbinil prevents the hypergalactosemic-induced reduction in [3H]-myo-inositol uptake and decreased [3H]-myo-inositol incorporation into the phosphoinositide cycle in bovine lens epithelial cells in vitro.
    Current eye research, 1990, Volume: 9, Issue:6

    Topics: Aldehyde Reductase; Animals; Cattle; Cells, Cultured; Chromatography, Ion Exchange; Epithelium; Galactitol; Galactose; Imidazoles; Imidazolidines; Inositol; Inositol Phosphates; Lens, Crystalline; Phosphatidylinositols; Phospholipids; Sugar Alcohol Dehydrogenases

1990
Effects of aldose reductase inhibitor sorbinil on neuroaxonal dystrophy and levels of myo-inositol and sorbitol in sympathetic autonomic ganglia of streptozocin-induced diabetic rats.
    Diabetes, 1989, Volume: 38, Issue:5

    Topics: Aldehyde Reductase; Animals; Axons; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Galactose; Ganglia, Sympathetic; Imidazoles; Imidazolidines; Inositol; Male; Rats; Rats, Inbred Strains; Sorbitol; Sugar Alcohol Dehydrogenases

1989
Galactose feeding causes glomerular hyperperfusion: prevention by aldose reductase inhibition.
    The American journal of physiology, 1989, Volume: 256, Issue:6 Pt 2

    Topics: Aldehyde Reductase; Animals; Galactose; Glomerular Filtration Rate; Imidazoles; Imidazolidines; Kidney Glomerulus; Male; Mathematics; Models, Theoretical; Naphthalenes; Nephrons; Rats; Rats, Inbred Strains; Reference Values; Sugar Alcohol Dehydrogenases

1989
Polyol and vacuole formation in cultured canine lens epithelial cells.
    Experimental eye research, 1989, Volume: 48, Issue:5

    Topics: Aldehyde Reductase; Ampholyte Mixtures; Animals; Buffers; Cell Division; Dogs; Epithelium; Galactose; Glucose; Imidazoles; Imidazolidines; Lens Capsule, Crystalline; Lens, Crystalline; Microscopy, Electron; Polymers; Vacuoles

1989
Increased urinary prostaglandin excretion in galactose-fed rats.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:7

    Topics: 6-Ketoprostaglandin F1 alpha; Aldehyde Reductase; Animals; Dietary Carbohydrates; Dinoprostone; Galactose; Imidazoles; Imidazolidines; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Reference Values

1989
Reversal of galactosemic-induced inhibition of PGH synthase activity in cultured lens epithelial cells.
    Current eye research, 1989, Volume: 8, Issue:10

    Topics: Animals; Cattle; Cells, Cultured; Cyclooxygenase Inhibitors; Epithelium; Galactitol; Galactose; Glutathione; Imidazoles; Imidazolidines; Lens, Crystalline; Phosphates; Polymers; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Radioimmunoassay

1989
Aldose reductase inhibitors and prevention of galactose cataracts in rats.
    Investigative ophthalmology & visual science, 1989, Volume: 30, Issue:7

    Topics: Aldehyde Reductase; Animals; Cataract; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Sugar Alcohol Dehydrogenases; Time Factors

1989
Effect of galactose and glucose levels and sorbinil treatment on myo-inositol metabolism and Na+-K+ pump activity in cultured neuroblastoma cells.
    Diabetes, 1989, Volume: 38, Issue:8

    Topics: Aldehyde Reductase; Animals; Cell Line; Galactose; Glucose; Imidazoles; Imidazolidines; Inositol; Mice; Neuroblastoma; Phosphatidylinositols; Polymers; Potassium Channels; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Tumor Cells, Cultured

1989
The accumulation of myoinositol and rubidium ions in galactose-exposed rat lens.
    Investigative ophthalmology & visual science, 1986, Volume: 27, Issue:10

    Topics: Aldehyde Reductase; Animals; Cataract; Galactose; Hypertonic Solutions; Imidazoles; Imidazolidines; Inositol; Lens, Crystalline; Male; Radioisotopes; Rats; Rubidium; Sodium-Potassium-Exchanging ATPase

1986
Galactose neuropathy. Structural changes evaluated by nuclear magnetic resonance spectroscopy.
    Diabetes, 1987, Volume: 36, Issue:6

    Topics: Animals; Galactose; Humans; Imidazoles; Imidazolidines; Magnetic Resonance Spectroscopy; Male; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains; Sciatic Nerve

1987
Aldose reductase activity and basement membrane thickening.
    Metabolism: clinical and experimental, 1986, Volume: 35, Issue:4 Suppl 1

    Topics: Aldehyde Reductase; Animals; Basement Membrane; Collagen; Diabetes Mellitus; Dogs; Female; Galactose; Galactosemias; Humans; Imidazoles; Imidazolidines; Mice; Microscopy, Electron; Rats; Rats, Inbred WKY; Retinal Vessels; Sugar Alcohol Dehydrogenases

1986
Non-competitive inhibition of myo-inositol transport in cultured bovine retinal capillary pericytes by glucose and reversal by Sorbinil.
    Biochimica et biophysica acta, 1986, May-28, Volume: 857, Issue:2

    Topics: 3-O-Methylglucose; Adenosine Triphosphate; Aldehyde Reductase; Animals; Biological Transport, Active; Calcium; Capillaries; Cattle; Cells, Cultured; Deoxyglucose; Galactose; Glucose; Hexoses; Imidazoles; Imidazolidines; Inositol; Kinetics; Manganese; Methylglucosides; Retina

1986
The polyol pathway in retinal microangiopathy.
    Drugs, 1986, Volume: 32 Suppl 2

    Topics: Aldehyde Reductase; Animals; Diabetic Retinopathy; Galactose; Imidazoles; Imidazolidines; Male; Naphthalenes; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases; Sugar Alcohols

1986
Galactose ingestion increases vascular permeability and collagen solubility in normal male rats.
    The Journal of clinical investigation, 1987, Volume: 79, Issue:2

    Topics: Aldehyde Reductase; Animals; Body Weight; Capillary Permeability; Collagen; Galactose; Imidazoles; Imidazolidines; Male; Naphthalenes; Organ Size; Prostate; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Solubility; Testosterone; Tissue Distribution

1987
Sorbinil prevents the galactose-induced inhibition of prostaglandin synthesis in lens cells.
    Investigative ophthalmology & visual science, 1988, Volume: 29, Issue:9

    Topics: Animals; Cattle; Cell Division; Galactose; Imidazoles; Imidazolidines; In Vitro Techniques; Lens, Crystalline; Microscopy, Electron; Microsomes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Radioimmunoassay

1988
[Diabetic changes in pupillary reactions and iris histology. No. 3. The role of aldose reductase inhibitor to iridal vessel hyperpermeability of galactose-fed rats].
    Nippon Ganka Gakkai zasshi, 1988, Volume: 92, Issue:10

    Topics: Aldehyde Reductase; Animals; Capillary Permeability; Diabetes Mellitus, Experimental; Galactose; Horseradish Peroxidase; Imidazoles; Imidazolidines; Iris; Male; Naphthalenes; Rats; Rats, Inbred Strains; Reflex, Pupillary; Sugar Alcohol Dehydrogenases

1988
[Prevention of pericyte ghost formation in retinal capillaries by aldose reductase inhibitor in galactose-fed dogs with diabetic retinopathy].
    Nippon Ganka Gakkai zasshi, 1988, Volume: 92, Issue:9

    Topics: Aldehyde Reductase; Animals; Capillaries; Diabetic Retinopathy; Dogs; Galactose; Imidazoles; Imidazolidines; Male; Retinal Vessels; Sugar Alcohol Dehydrogenases

1988
Increased ocular blood flow and 125I-albumin permeation in galactose-fed rats: inhibition by sorbinil.
    Investigative ophthalmology & visual science, 1988, Volume: 29, Issue:6

    Topics: Animals; Brain; Capillary Permeability; Diet; Eye; Galactose; Imidazoles; Imidazolidines; Iodine Radioisotopes; Permeability; Polymers; Regional Blood Flow; Serum Albumin, Bovine

1988
Acid phosphatase II. Cytochemical localization in lenses of normal and galactose-fed rats.
    Experimental eye research, 1985, Volume: 40, Issue:1

    Topics: Acid Phosphatase; Aldehyde Reductase; Animals; Cataract; Female; Galactose; Histocytochemistry; Imidazoles; Imidazolidines; Lens, Crystalline; Lysosomes; Microscopy, Electron; Rats; Rats, Inbred Strains

1985
Reversal of stage-I sugar cataract by Sorbinil, an aldose reductase inhibitor.
    Pharmacology, 1985, Volume: 31, Issue:2

    Topics: Aldehyde Reductase; Animals; Cataract; Diet; Female; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases

1985
Synergism of sorbinil and normal diet on reversal of stage-II sugar cataract.
    Pharmacology, 1985, Volume: 31, Issue:3

    Topics: Aldehyde Reductase; Animals; Cataract; Combined Modality Therapy; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Male; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases

1985
Retinal dystrophy: development retarded by galactose feeding in spontaneously hypertensive rats.
    Science (New York, N.Y.), 1986, Jan-24, Volume: 231, Issue:4736

    Topics: Age Factors; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Female; Galactose; Humans; Imidazoles; Imidazolidines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Retina; Retinal Degeneration

1986
Ultrastructural cytochemistry: effect of Sorbinil on arylsulfatases in cataractous lenses.
    Current eye research, 1985, Volume: 4, Issue:6

    Topics: Animals; Arylsulfatases; Cataract; Epithelium; Female; Galactose; Imidazoles; Imidazolidines; Kinetics; Lens, Crystalline; Lysosomes; Microscopy, Electron; Rats; Rats, Inbred Strains; Sulfatases; Wound Healing

1985
Inhibition of galactose-induced alterations in ocular lens with sorbinil.
    Experimental eye research, 1983, Volume: 36, Issue:5

    Topics: 4-Nitrophenylphosphatase; Aldehyde Reductase; Animals; Cataract; Female; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Microscopy, Electron; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase

1983
Galactose-induced retinal capillary basement membrane thickening: prevention by Sorbinil.
    Investigative ophthalmology & visual science, 1983, Volume: 24, Issue:11

    Topics: Animals; Basement Membrane; Female; Galactose; Imidazoles; Imidazolidines; Rats; Rats, Inbred Strains; Retinal Diseases; Retinal Vessels

1983
Galactose cataract prevention with sorbinil, an aldose reductase inhibitor: a light microscopic study.
    Investigative ophthalmology & visual science, 1982, Volume: 22, Issue:2

    Topics: Aldehyde Reductase; Animals; Cataract; Galactose; Imidazoles; Imidazolidines; Male; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases

1982
Role of nonenzymatic glycosylation in experimental cataract formation.
    Biochemical and biophysical research communications, 1980, Jul-31, Volume: 95, Issue:2

    Topics: Animals; Cataract; Disease Models, Animal; Galactose; Galactosemias; Glycoproteins; Imidazoles; Imidazolidines; Lens, Crystalline; Proteins; Rats

1980
Time-dependent aspects of osmolyte changes in rat kidney, urine, blood and lens with sorbinil and galactose feeding.
    Kidney international, 1995, Volume: 48, Issue:2

    Topics: Aldehyde Reductase; Animal Feed; Animals; Blood; Drug Combinations; Galactose; Imidazoles; Imidazolidines; Kidney; Lens, Crystalline; Male; Rats; Rats, Wistar; Time Factors; Urine

1995
Sorbinil prevention of diabetic-like retinopathy in the galactose-fed rat model.
    Investigative ophthalmology & visual science, 1995, Volume: 36, Issue:12

    Topics: Aldehyde Reductase; Animals; Capillaries; Cataract; Diabetic Retinopathy; Disease Models, Animal; Enzyme Inhibitors; Galactose; Image Processing, Computer-Assisted; Imidazoles; Imidazolidines; Male; Rats; Rats, Sprague-Dawley; Retinal Vessels

1995
Regulation of aldose reductase gene expression in renal cortex and medulla of rats.
    Diabetologia, 1995, Volume: 38, Issue:1

    Topics: Actins; Aldehyde Reductase; Animals; Blotting, Northern; Galactose; Gene Expression Regulation, Enzymologic; Imidazoles; Imidazolidines; Kidney Cortex; Kidney Medulla; Male; Phenotype; Rats; Rats, Sprague-Dawley; RNA, Messenger

1995
Galactose-induced retinal microangiopathy in rats.
    Investigative ophthalmology & visual science, 1995, Volume: 36, Issue:2

    Topics: Aldehyde Reductase; Animals; Basement Membrane; Capillaries; Cataract; Diabetic Retinopathy; Disease Models, Animal; Erythrocytes; Galactitol; Galactose; Galactosemias; Imidazoles; Imidazolidines; Male; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels; Sciatic Nerve

1995
Amelioration of diabetes-like retinal changes in galactose-fed dogs.
    Preventive medicine, 1994, Volume: 23, Issue:5

    Topics: Aldehyde Reductase; Animals; Cataract; Diabetic Retinopathy; Dogs; Dose-Response Relationship, Drug; Galactose; Imidazoles; Imidazolidines; Male; Retina; Retinal Vessels

1994
Aldose reductase inhibitors and galactose toxicity in neonatal and maternal rat lenses.
    Journal of ocular pharmacology, 1993,Winter, Volume: 9, Issue:4

    Topics: Aldehyde Reductase; Animals; Animals, Newborn; Cataract; Female; Galactitol; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Sprague-Dawley

1993
Osmoregulatory alterations in myo-inositol uptake by bovine lens epithelial cells. Part 1: A hypertonicity-induced protein enhances myo-inositol transport.
    Investigative ophthalmology & visual science, 1994, Volume: 35, Issue:3

    Topics: Aldehyde Reductase; Animals; Biological Transport; Carrier Proteins; Cattle; Cells, Cultured; Cycloheximide; Epithelium; Galactitol; Galactose; Heat-Shock Proteins; Hypertonic Solutions; Imidazoles; Imidazolidines; Inositol; Lens, Crystalline; Membrane Proteins; Symporters; Water-Electrolyte Balance

1994
Suppression of pentosidine formation in galactosemic rat lens by an inhibitor of aldose reductase.
    Diabetes, 1994, Volume: 43, Issue:4

    Topics: Aldehyde Reductase; Animals; Arginine; Ascorbic Acid; Diet; Female; Galactitol; Galactose; Galactosemias; Glutathione; Imidazoles; Imidazolidines; Lens, Crystalline; Lysine; Maillard Reaction; Rats; Rats, Sprague-Dawley; Time Factors

1994
Quantitative analysis of retinal vessel changes in galactose-fed dogs.
    Journal of ocular pharmacology, 1993,Fall, Volume: 9, Issue:3

    Topics: Aldehyde Reductase; Animals; Cataract; Cell Count; Diabetic Retinopathy; Dogs; Endothelium, Vascular; Galactose; Image Processing, Computer-Assisted; Imidazoles; Imidazolidines; Male; Retinal Vessels

1993
Inhibition of naphthalene cataract in rats by aldose reductase inhibitors.
    Current eye research, 1996, Volume: 15, Issue:4

    Topics: Aldehyde Reductase; Animals; Cataract; Culture Techniques; Disease Models, Animal; Enzyme Inhibitors; Fluorenes; Galactose; Hydantoins; Imidazoles; Imidazolidines; Male; Naphthalenes; Rats; Spiro Compounds

1996
Nuclear magnetic resonance studies of sugar metabolism in the human infant lens.
    Ophthalmic research, 1996, Volume: 28 Suppl 2

    Topics: Aldehyde Reductase; Carbon Isotopes; Child, Preschool; Enzyme Inhibitors; Galactose; Glucose; Humans; Imidazoles; Imidazolidines; Infant; Infant, Newborn; Lens, Crystalline; Magnetic Resonance Spectroscopy; Pentose Phosphate Pathway; Polymers; Retinopathy of Prematurity; Vitrectomy

1996
Comparison of the effects of Zopolrestat and Sorbinil on lens myo-inositol influx.
    Pharmacology, 1997, Volume: 54, Issue:2

    Topics: Aldehyde Reductase; Animals; Benzothiazoles; Carbohydrate Metabolism; Carbohydrates; Culture Media; Enzyme Inhibitors; Galactose; Glucose; Imidazoles; Imidazolidines; In Vitro Techniques; Inositol; Lens, Crystalline; Male; Phthalazines; Polymers; Rats; Rats, Sprague-Dawley; Sorbitol; Thiazoles

1997
Osmoregulatory alterations in taurine uptake by cultured human and bovine lens epithelial cells.
    Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:2

    Topics: Aldehyde Reductase; Animals; Biological Transport; Carrier Proteins; Cattle; Cells, Cultured; Epithelial Cells; Galactitol; Galactose; Humans; Imidazoles; Imidazolidines; Lens, Crystalline; Membrane Glycoproteins; Membrane Transport Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Taurine; Up-Regulation; Water-Electrolyte Balance

2002
Competitive inhibition by glucose of myo-inositol incorporation into cultured porcine aortic endothelial cells.
    Biochimica et biophysica acta, 1990, Apr-09, Volume: 1052, Issue:1

    Topics: Aldehyde Reductase; Animals; Aorta, Thoracic; Biological Transport; Cells, Cultured; Cytochalasin B; Endothelium, Vascular; Glucose; Hexoses; Imidazoles; Imidazolidines; Inositol; Insulin; Kinetics; Ouabain; Sodium; Swine

1990
L-Idose: an attractive substrate alternative to D-glucose for measuring aldose reductase activity.
    Biochemical and biophysical research communications, 2015, Jan-24, Volume: 456, Issue:4

    Topics: Aldehyde Reductase; Animals; Biocatalysis; Cattle; Glucose; Hexoses; Humans; Imidazolidines; Kinetics; Oxidation-Reduction; Substrate Specificity

2015