galactose has been researched along with galactitol in 150 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 44 (29.33) | 18.7374 |
| 1990's | 51 (34.00) | 18.2507 |
| 2000's | 37 (24.67) | 29.6817 |
| 2010's | 15 (10.00) | 24.3611 |
| 2020's | 3 (2.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukushi, S; Kador, P; Kinoshita, JH; Merola, LO | 1 |
| Aldinger, CE; MacDonald, DP; Peterson, MJ; Sarges, R | 1 |
| Hothersall, JS; McLean, P | 1 |
| Chakrapani, B; Lim, CP; Reddy, VN; Schwass, D | 1 |
| Bremner, DA; Gavin, JB; Joshi, KR; Parr, DN | 1 |
| Hoppel, CL; Tandler, B | 1 |
| Bergren, WR; Donnell, GN; Ng, WG | 1 |
| Sato, S | 1 |
| Johnson, MJ; Tsui, JY; Unakar, NJ | 1 |
| DeCherney, AH; Diamond, MP; Doyle, MB; Grifo, JA; Lipetz, KJ; Meyer, WR; Oates, PJ | 1 |
| Devamanoharan, PS; Henein, M; Ramachandran, S; Varma, SD | 1 |
| Chakrapani, B; Giblin, FJ; Lin, LR; Reddy, VN; Yokoyama, T | 1 |
| Cammarata, PR; Tse, D; Yorio, T | 2 |
| Calcutt, NA; Tomlinson, DR; Willars, GB | 2 |
| Gould, S; Lyons, PA; Palmer, TN; Wise, PH | 1 |
| Hayashi, M; Mino, M; Yamazaki, T | 1 |
| Giblin, FJ; Kador, PF; Kinoshita, JH; Lin, LR; Reddy, VN | 1 |
| Gupta, SK; Joshi, S | 1 |
| Bauman, JG; Dietrich, A; Gorham, BJ; Harrison, MC; Jones, LR; Kelly, JM; Malamas, M; Millen, J; Sredy, J; Wrobel, J | 1 |
| Akagi, Y; Ikebe, H; Kador, PF; Kinoshita, JH; Takahashi, Y; Wyman, M | 1 |
| Brockstedt, M; Douwes, AC; Endres, W; Jakobs, C; Shin, YS; Stellaard, F | 1 |
| Cheng, HM; Tsubota, K; Xiong, H; Xiong, J | 1 |
| Armstrong, GR; Bascal, ZA; Wolff, SP; Woollard, AC | 1 |
| Alloussi, S; Birlouez-Aragon, I | 1 |
| McLean, WG | 1 |
| Alloussi, S; Birlouez-Aragon, I; Fevrier, C; Morawiec, M | 1 |
| Cammarata, PR; Jackson, T; Lou, M; Yorio, T | 1 |
| Brazzell, RK; Chandler, ML; Dickerson, JE; Lou, MF; York, BM | 1 |
| Alloussi, S; Birlouez-Aragon, I; Fevrier, C; Papadopoulos, H | 1 |
| Cherruau, B; Djabal, A; Lemonnier, A; Mangeot, M; Myara, I; Pourci, ML | 1 |
| Merola, LO; Ng, MC; Tsui, JY; Unakar, NJ | 1 |
| Awata, T; Sogo, S; Yamamoto, Y | 1 |
| Allen, JT; Hodges, IC; Holton, JB; Lennox, AC | 1 |
| Ansari, NH; Srivastava, SK | 1 |
| Reddy, VN; Taura, T | 1 |
| Bakker, HD; Jakobs, C; Kleijer, WJ; Niermeijer, MF; Przyrembel, H; van Gennip, AH | 1 |
| Bessard, C; Birlouez, I; Dillon, JC; Lestradet, H | 1 |
| Adrian, J; Kechrid, RM; Poiffait, A | 2 |
| Bachmann, C; Schaefer, T; Schwarz, HP | 1 |
| Creighton, MO; Ross, WM; Sanwal, M; Stewart-DeHaan, PJ; Trevithick, JR | 1 |
| Dvornik, D; Gonzalez, R; Greselin, E; Simard-Duquesne, N | 1 |
| Kaul, S; Saxena, SC | 1 |
| Bert, M; Hilliard, R; Monteleone, JA; Monteleone, PL | 1 |
| Kinoshita, JH; Varma, SD | 1 |
| Dvornik, D; Simard-Duquesne, N | 1 |
| Bergren, WR; Donnell, GN; Ng, WG; Roe, TF | 1 |
| Pachler, KG; Rathbone, EB; Stephen, AM | 1 |
| El-Aguizy, HK; Richards, RD; Varma, SD | 1 |
| Low, PA; Schmelzer, JD; Tuck, RR | 1 |
| Henle, KJ; Monson, TP; Moss, AJ; Nagle, WA | 1 |
| Simoons, FJ | 1 |
| Adrian, J; David, C; Poiffait, A | 1 |
| Szumiło, T | 1 |
| Julia, C; Kador, PF; Neuenschwander, H; Wyman, M | 1 |
| Dorland, B; Jakobs, C; Schweitzer, S | 1 |
| Chung, SK; Chung, SS; Lee, AY | 1 |
| Basso, M; Cherian, PV; Hohman, TC; Kamijo, M; Sima, AA | 1 |
| Engerman, RL; Kern, TS | 2 |
| Eaton, RP; Griffey, BV; Griffey, RH; Hunsaker, LA; Sibbitt, RR; Sibbitt, WL; Vander Jagt, DL | 1 |
| Kienzle, E | 1 |
| Epstein, M; Forster, HG; Hohman, TC; Takenaka, T; ter Wee, PM | 1 |
| Anthony, P; Johnson, M; Tsui, J; Unakar, NJ | 1 |
| Cammarata, PR; Chen, HQ | 1 |
| Bekhor, I; Kannan, R; Mackic, JB; McComb, JG; Ross-Cisneros, FN; Weiss, MH; Zlokovic, BV | 1 |
| Monnier, VM; Nagaraj, RH; Ortwerth, BJ; Prabhakaram, M | 1 |
| Giblin, FJ; Reddy, VN; Sasaki, H; Yokoyama, T | 1 |
| Akagi, Y; Ikebe, H; Okamoto, S; Tanimoto, T; Terubayashi, H; Tsuji, T | 1 |
| Okamura, R; Taura, T; Teshima, R | 1 |
| Chung, S; Lyons, PA; Palmer, TN; Sainsbury, AJ; Wang, A; Wu, RR | 1 |
| Acosta, PB; Berry, GT; Gross, KC; Henstenburg, JA; Mazur, A; Palmieri, M; Reynolds, R; Segal, S | 1 |
| Huckerby, TN; Nieduszynski, IA; Tai, GH | 1 |
| Baba, M; Fujimoto, J; Kokai, Y; Nishimura, C; Sugimoto, K; Wada, R; Wong, HG; Yagihashi, S; Yamagishi, S | 1 |
| Breen, SA; Carey, F; Mirrlees, DJ; Sennitt, CM; Waterton, JC | 1 |
| Cammarata, PR; Reeves, RE | 1 |
| Basso, MD; Blouin, P; Glover, JP; Hohman, TC; Jacot, JL; Laver, NM; Robinson, WG | 1 |
| Epstein, M; Forster, HG; Hohman, TC; ter Wee, PM | 1 |
| Burgan, J; Faller, A; Obrosova, I; Ostrow, E; Williamson, JR | 1 |
| Blum, PS; Jernigan, HM; Liu, Y; Merola, LO; Stimbert, CD; Zigler, JS | 1 |
| Horikoshi, H; Inoue, T; Yokoyama, T; Yoshida, Y | 1 |
| Ishiguro, I; Majima, Y; Niwa, T; Ohta, Y; Yamasaki, T | 1 |
| Andrade, J; Eu, JY; Wang, CY | 1 |
| Goto, H; Ishiguro, I; Majima, Y; Niwa, T; Ohta, Y; Yamasaki, T | 1 |
| Berkowitz, BA; Frank, RN; Hohman, TC; Kern, TS; Kowluru, RA; Prakash, M | 1 |
| Banditelli, S; Boldrini, E; Cappiello, M; Cecconi, I; Dal Monte, M; Del Corso, A; Marini, I; Mura, U; Vilardo, PG | 1 |
| Ali, AH; Devamanoharan, PS; Henein, M; Varma, SD | 1 |
| Chaya, S; Hamada, Y; Hotta, N; Ito, M; Kasuya, Y; Kato, K; Koh, N; Komori, T; Nakamura, J; Nakashima, E; Nakayama, M; Naruse, K | 1 |
| Ai, Y; Bernard, DJ; Huang, K; Ning, C; O'Brien-Jenkins, A; Reynolds, R; Segal, S; Stambolian, D; Wynshaw-Boris, T; Zheng, Z | 1 |
| Majima, Y; Niwa, T; Ohta, Y; Yamasaki, T | 1 |
| Ning, C; Segal, S | 1 |
| Alam, S; Kador, PF; Murata, M; Ohta, N; Sakurai, S; Sato, S; Tsai, J | 1 |
| Chen, J; Reynolds, R; Segal, S; Wehrli, SL; Yager, C | 1 |
| Cammarata, PR; Chen, SW; Guo, Z; Reeves, RE; Schafer, G | 1 |
| Marinou, K; Schulpis, KH; Tsakiris, S | 1 |
| Elsas, LJ; Kennedy, MJ; Singh, RH; Webb, AL | 1 |
| Akagi, Y; Kubo, E; Takamura, Y; Tsuzuki, S | 1 |
| DUPUIS, Y; FOURNIER, P; SUSBIELLE, H | 1 |
| EGAN, TJ; PITTMAN, TA; WELLS, WW | 1 |
| DIKMAK, E; KINOSHITA, JH; MEROLA, LO | 1 |
| DIKMAK, E; KINOSHITA, JH; MEROLA, LO; SATOH, K | 1 |
| Hammen, HW; Kamalanathan, L; Killius, S; Schadewaldt, P; Strassburger, K; Wendel, U | 1 |
| Bányai, I; Fekete, E; Gyémánt, G; Karaffa, L; Kubicek, CP; Sándor, E; Seiboth, B; Sepsi, A; Szentirmai, A | 1 |
| Hammen, HW; Kamalanathan, L; Schadewaldt, P; Wendel, U | 2 |
| Hammen, HW; Kamalanathan, L; Schadewaldt, P; Stolpmann, S; Wendel, U | 1 |
| Fekete, E; Hartl, L; Karaffa, L; Kubicek, CP; Pail, M; Seiboth, B | 1 |
| Behrakis, P; Marinou, K; Schulpis, KH; Tsakiris, S | 1 |
| Hegde, KR; Kalakonda, S; Varma, SD | 1 |
| Bakker, HD; Bosch, AM; Wanders, RJ; Wenniger-Prick, LJ; Wijburg, FA | 1 |
| Behrakis, P; Marinou, K; Schulpis, KH; Tsakiris, S; Tsopanakis, C | 2 |
| Fekete, E; Gamauf, C; Karaffa, L; Kubicek, CP; Seiboth, B; Szentirmai, A | 1 |
| de Lederkremer, RM; Gallo-Rodriguez, C; Gandolfi-Donadío, L; Gola, G | 1 |
| Brunetti-Pierri, N; Craigen, WJ; Opekun, AR | 1 |
| Fekete, E; Karaffa, L; Kubicek, CP; Seiboth, B; Szentirmai, A | 1 |
| Mach, RL; Steiger, MG; Stricker, AR | 1 |
| Geyer, A; Klein, S; Loos, E; Wieneke, R | 1 |
| Cisnetti, F; Guillot, R; Ibrahim, N; Lambert, F; Policar, C; Thérisod, M | 1 |
| Bro, C; de Jongh, WA; Nielsen, J; Olsson, L; Ostergaard, S; Regenberg, B | 1 |
| Cuthbert, C; Elsas, L; Klapper, H | 1 |
| Navarro, DA; Stortz, CA | 1 |
| Calcutt, NA; Cunha, JM; Gregory, JA; Jolivalt, CG; Mizisin, AP; Ramos, KM | 1 |
| Boers, GH; Bosch, AM; Guion, N; Hammen, HW; Janssen, M; Kamalanathan, L; Schadewaldt, P; Schwarz, M; Wendel, U | 1 |
| Day-Salvatore, DL; Ficicioglu, C; Forbes, BJ; Gallagher, PR; Hussa, C; Mattie, A; Thomas, N; Yager, C | 1 |
| Clark, A; Geoghegan, O; Hendroff, U; Hughes, J; Lambert, D; Monavari, A; Rogers, Y; Ryan, S; Treacy, EP; Twomey, E | 1 |
| Blessing, K; Hosoya, K; Kador, PF; Makita, J; Randazzo, J; Terasaki, T; Yu, K; Zhang, P | 1 |
| Elsas, LJ; Lai, K; Wierenga, KJ | 1 |
| Christ, TN; Deweese, KA; Woodyer, RD | 1 |
| Hegde, KR; Kovtun, S; Varma, SD | 1 |
| Fernhoff, PM | 1 |
| Ficicioglu, C; Gallagher, PR; Hussa, C; Thomas, N; Yager, C | 1 |
| Hennermann, JB; Klein, J; Mönch, E; Schadewaldt, P; Shin, YS; Vetter, B | 1 |
| Joost, K; Krabbi, K; Õunap, K; Uudelepp, ML; Zordania, R | 1 |
| Koivistoinen, OM; Maaheimo, H; Mojzita, D; Penttilä, M; Richard, P; Ruohonen, L | 1 |
| Haggarty, NW; He, X; Lönnerdal, B; McNiven, EM; O'Sullivan, A; Slupsky, CM | 1 |
| Kador, PF; Zhang, P; Zhang, Z | 1 |
| Inatani, M; Matsumoto, T; Matsumura, T; Takamura, Y; Takihara, Y; Tomomatsu, T | 1 |
| Dhepe, PL; Tathod, AP | 1 |
| Abu-Soud, HM; Aldhaheri, SR; Gonik, B; Jeelani, R; Khan, SN; Kohan-Ghadr, HR; Shaeib, F; Thakur, M | 1 |
| Badertscher, R; Burton, KJ; Freiburghaus, C; Münger, LH; Pimentel, G; Pralong, FP; Vergères, G; Vionnet, N | 1 |
| Blaga, L; Căinap, SS; Deleanu, C; Fufezan, O; Grama, A; Militaru, M; Nicolescu, A; Pop, I; Pop, TL; Sîrbe, C; Tita, G; Vințan, MA; Vulturar, R | 1 |
| Arai-Ichinoi, N; Kikuchi, A; Kure, S; Wada, Y | 1 |
| An, Y; Huang, J; Li, X; Qi, X; Ravikumar, Y; Wang, J; Yun, J; Zabed, HM; Zhang, G; Zhang, Y | 1 |
| Gray, GR; Que, L | 1 |
| Brinkkötter, A; Lengeler, JW; Schmid, K; Shakeri-Garakani, A; Turgut, S | 1 |
| Finan, TM; Fowler, JE; Kohlmeier, MG; Oresnik, IJ; White, CE | 1 |
| Bilal, M; Cheng, H; Chi, P; Lv, J; Xu, Y | 1 |
2 review(s) available for galactose and galactitol
| Article | Year |
|---|---|
Aldose reductase in diabetic complications of the eye.
Topics: Aldehyde Reductase; Animals; Cataract; Cattle; Chromans; Cornea; Diabetes Complications; Diabetic Retinopathy; Epithelium; Eye Diseases; Female; Galactitol; Galactose; Humans; Imidazoles; Imidazolidines; Lens, Crystalline; Mice; Mice, Obese; NADP; Polymers; Pregnancy; Rats; Regeneration; Retina; Rodentia; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases; Xylitol | 1979 |
Galactose toxicity in animals.
Topics: Animals; Galactitol; Galactokinase; Galactose; Galactosemias; Galactosephosphates; Humans; Infant, Newborn; Inositol; Models, Animal; Neonatal Screening; UDPglucose 4-Epimerase; UTP-Hexose-1-Phosphate Uridylyltransferase | 2009 |
1 trial(s) available for galactose and galactitol
| Article | Year |
|---|---|
Verbal dyspraxia and galactosemia.
Topics: Adult; Apraxias; Breath Tests; Carbon Dioxide; Carbon Isotopes; Child; Erythrocytes; Female; Galactitol; Galactose; Galactosemias; Galactosephosphates; Genotype; Humans; Male; Phenotype; Prospective Studies; Reproducibility of Results; Risk Factors; Sensitivity and Specificity | 2003 |
147 other study(ies) available for galactose and galactitol
| Article | Year |
|---|---|
CP-45,634: a novel aldose reductase inhibitor that inhibits polyol pathway activity in diabetic and galactosemic rats.
Topics: Aldehyde Reductase; Animals; Benzopyrans; Cataract; Chromans; Diabetes Mellitus, Experimental; Galactitol; Galactose; Galactosemias; Imidazoles; Imidazolidines; Kinetics; Lens, Crystalline; Male; Polymers; Rats; Sciatic Nerve; Sorbitol; Sugar Alcohol Dehydrogenases | 1979 |
Effect of experimental diabetes and insulin onphosphatidyl-inositol synthesis in rat sciatic nerve.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Galactitol; Galactose; Glucose; Inositol; Insulin; Male; Peripheral Nerves; Phosphatidylinositols; Rats; Sorbitol; Streptozocin | 1979 |
Biochemical changes associated with the development and reversal of galactose cataracts.
Topics: Amino Acids; Animals; Cataract; Female; Galactitol; Galactose; Glutathione; Lens, Crystalline; Potassium; Rats; Sodium; Time Factors; Water | 1976 |
The morphological identification of pathogenic yeasts using carbohydrate media.
Topics: Agar; Candida; Candida albicans; Carbohydrates; Cryptococcus; Cryptococcus neoformans; Culture Media; Dextrins; Fructose; Galactitol; Galactose; Glucose; Glycogen; Inulin; Maltose; Mannitol; Oryza; Peptones; Saccharomyces cerevisiae; Spores, Fungal; Sucrose; Trehalose; Xylose; Yeasts | 1975 |
Riboflavin and mouse hepatic cell structure and function. Mitochondrial oxidative metabolism in severe deficiency states.
Topics: Adenosine Diphosphate; Animals; Body Weight; Color; Galactitol; Galactose; Liver; Male; Mice; Mitochondria, Liver; Organ Size; Oxidative Phosphorylation; Oxygen Consumption; Proteins; Riboflavin; Riboflavin Deficiency | 1975 |
Mannitol excretion in galactosemia patients.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Glucose; Erythrocytes; Fructose; Galactitol; Galactose; Galactosemias; Humans; Mannitol | 1975 |
Rat kidney aldose reductase and aldehyde reductase and polyol production in rat kidney.
Topics: Aldehyde Reductase; Animals; Chromatography, Gas; Diet; Female; Fluorenes; Galactitol; Galactose; Hydantoins; Kidney; Polymers; Rats; Rats, Sprague-Dawley; Sorbitol | 1992 |
Effect of aldose reductase inhibitors on lenticular dulcitol level in galactose fed rats.
Topics: Aldehyde Reductase; Animals; Cataract; Dietary Carbohydrates; Galactitol; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Rats; Rats, Sprague-Dawley | 1992 |
Aldose reductase inhibition prevents galactose-induced ovarian dysfunction in the Sprague-Dawley rat.
Topics: Aldehyde Reductase; Animals; Female; Galactitol; Galactose; Granulosa Cells; Ovarian Diseases; Ovary; Rats; Rats, Sprague-Dawley | 1992 |
Prevention of galactose cataract by pyruvate.
Topics: Adenosine Triphosphate; Animals; Cataract; Crystallins; Diet; Disease Models, Animal; Galactitol; Galactose; Lens, Crystalline; Ophthalmic Solutions; Organ Culture Techniques; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sorbitol | 1992 |
Study of the polyol pathway and cell permeability changes in human lens and retinal pigment epithelium in tissue culture.
Topics: Adult; Aldehyde Reductase; Cell Membrane Permeability; Cells, Cultured; Chromatography, High Pressure Liquid; Epithelium; Galactitol; Galactose; Glutathione; Humans; Inositol; Lens, Crystalline; Middle Aged; Pigment Epithelium of Eye; Taurine | 1992 |
Depletion of glutathione by L-buthionine sulfoximine does not promote inactivation of myo-inositol transport in cultured bovine lens epithelial cells.
Topics: Animals; Antimetabolites; Biological Transport, Active; Buthionine Sulfoximine; Cattle; Cells, Cultured; Dithiothreitol; Epithelial Cells; Epithelium; Galactitol; Galactose; Glutamate-Cysteine Ligase; Glutathione; Inositol; Lens, Crystalline; Methionine Sulfoximine | 1991 |
Nerve conduction velocity and axonal transport of 6-phosphofructokinase activity in galactose-fed rats.
Topics: Aldehyde Reductase; Animals; Axonal Transport; Blood Glucose; Body Weight; Carbohydrate Metabolism; Diet; Electrophysiology; Galactitol; Galactose; Hypoxia; Inositol; Male; Motor Neurons; Neural Conduction; Phosphofructokinase-1; Phthalazines; Rats; Rats, Inbred Strains; Sciatic Nerve | 1991 |
Activation of erythrocyte aldose reductase in man in response to glycaemic challenge.
Topics: Adult; Aldehyde Reductase; Blood Glucose; Enzyme Activation; Erythrocytes; Female; Galactitol; Galactose; Humans; In Vitro Techniques; Male | 1991 |
Urinary and serum galactitol in galactosemic patients.
Topics: Child; Child, Preschool; Galactitol; Galactose; Galactosemias; Humans; Infant; Male | 1991 |
Polyol accumulation in cultured human lens epithelial cells.
Topics: Aldehyde Reductase; Cells, Cultured; Epithelial Cells; Epithelium; Fluorenes; Galactitol; Galactose; Humans; Hydantoins; Imidazoles; Imidazolidines; Inositol; Lens, Crystalline; Microscopy, Electron; Microscopy, Phase-Contrast; Polymers; Reference Values; Stereoisomerism; Vacuoles | 1991 |
Naproxen: an aldose reductase inhibitor and potential anti-cataract agent.
Topics: Aldehyde Reductase; Animals; Cataract; Dogs; Galactitol; Galactose; Goats; Humans; In Vitro Techniques; Lens, Crystalline; Naproxen; Ophthalmic Solutions; Rats; Taurine | 1991 |
Syntheses of tolrestat analogues containing additional substituents in the ring and their evaluation as aldose reductase inhibitors. Identification of potent, orally active 2-fluoro derivatives.
Topics: Administration, Oral; Aldehyde Reductase; Animals; Cattle; Chemical Phenomena; Chemistry; Diabetes Mellitus, Experimental; Diaphragm; Galactitol; Galactose; Glycine; Lens, Crystalline; Male; Molecular Structure; Naphthalenes; Prodrugs; Rats; Rats, Inbred Strains; Sciatic Nerve | 1991 |
Prevention of retinal vessel changes associated with diabetic retinopathy in galactose-fed dogs by aldose reductase inhibitors.
Topics: Aldehyde Reductase; Aneurysm; Animals; Capillaries; Diabetic Retinopathy; Dogs; Dose-Response Relationship, Drug; Female; Galactitol; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Male; Retinal Vessels; Sugar Alcohol Dehydrogenases | 1990 |
Plasma polyol levels in patients with cataract.
Topics: Carbohydrate Epimerases; Cataract; Child, Preschool; Galactitol; Galactokinase; Galactose; Heterozygote; Homozygote; Humans; Infant; Infant, Newborn; Mutation; Polymers; Sorbitol; UDPglucose 4-Epimerase; UTP-Hexose-1-Phosphate Uridylyltransferase | 1990 |
Sorbinil prevents the hypergalactosemic-induced reduction in [3H]-myo-inositol uptake and decreased [3H]-myo-inositol incorporation into the phosphoinositide cycle in bovine lens epithelial cells in vitro.
Topics: Aldehyde Reductase; Animals; Cattle; Cells, Cultured; Chromatography, Ion Exchange; Epithelium; Galactitol; Galactose; Imidazoles; Imidazolidines; Inositol; Inositol Phosphates; Lens, Crystalline; Phosphatidylinositols; Phospholipids; Sugar Alcohol Dehydrogenases | 1990 |
Metabolic studies of galactosemic cataract.
Topics: Animals; Cataract; Galactitol; Galactose; Galactosemias; Lens, Crystalline; Magnetic Resonance Spectroscopy; Male; Osmolar Concentration; Phosphorus; Rats; Rats, Inbred Strains | 1990 |
Abnormal redox status without increased lipid peroxidation in sugar cataract.
Topics: Animals; Antioxidants; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cataract; Diabetic Retinopathy; Galactitol; Galactose; Glutathione; Lens, Crystalline; Lipid Peroxidation; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1990 |
Effect of prolonged galactose consumption on galactose tolerance in young healthy humans.
Topics: Adult; Blood Glucose; Dietary Carbohydrates; Dose-Response Relationship, Drug; Female; Galactitol; Galactokinase; Galactose; Galactosemias; Glycosylation; Humans; Male; Sex Factors; Sugar Alcohols; Time Factors | 1990 |
Pressure-induced inhibition of fast axonal transport of proteins in the rabbit vagus nerve in galactose neuropathy: prevention by an aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Axonal Transport; Cranial Nerve Diseases; Galactitol; Galactose; Male; Phthalazines; Pressure; Pyridazines; Rabbits; Reference Values; Sugar Alcohol Dehydrogenases; Vagus Nerve | 1988 |
The effects of 5% and 25% galactose diets on lens polyols, glutathione and protein glycation in male and female pigs.
Topics: Animals; Cataract; Chromatography, Gas; Chromatography, High Pressure Liquid; Diet; Female; Galactitol; Galactose; Glutathione; Inositol; Lens, Crystalline; Lysine; Male; Sex Factors; Sorbitol; Sugar Alcohols; Swine; Time Factors | 1989 |
Reversal of galactosemic-induced inhibition of PGH synthase activity in cultured lens epithelial cells.
Topics: Animals; Cattle; Cells, Cultured; Cyclooxygenase Inhibitors; Epithelium; Galactitol; Galactose; Glutathione; Imidazoles; Imidazolidines; Lens, Crystalline; Phosphates; Polymers; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Radioimmunoassay | 1989 |
The prevention of biochemical changes in lens, retina, and nerve of galactosemic dogs by the aldose reductase inhibitor AL01576.
Topics: Administration, Oral; Aldehyde Reductase; Analysis of Variance; Animals; Dogs; Fluorenes; Galactitol; Galactose; Galactosemias; Glutathione; Hydantoins; Inositol; Lens, Crystalline; Male; Retina; Sciatic Nerve; Sugar Alcohol Dehydrogenases | 1989 |
Effect of 5% galactose diet on galactose and dulcitol in plasma and lens of male and female pigs.
Topics: Analysis of Variance; Animals; Dietary Carbohydrates; Female; Galactitol; Galactose; Galactosemias; Lens, Crystalline; Male; Sex Factors; Sugar Alcohols; Swine | 1989 |
Metabolic studies of a sustained galactose overload in rat.
Topics: Animals; Diet; Disease Models, Animal; Galactitol; Galactokinase; Galactose; Galactosephosphates; Liver; Male; Nucleotidyltransferases; Rats; Rats, Inbred Strains; UDPglucose-Hexose-1-Phosphate Uridylyltransferase | 1987 |
Effect of prolactin on galactose cataractogenesis.
Topics: Animals; Cataract; Female; Galactitol; Galactose; Lens, Crystalline; Prolactin; Rats; Sodium-Potassium-Exchanging ATPase | 1987 |
Effects of aldose reductase inhibitor, CT-112, on sugar alcohol accumulation in corneal epithelium of galactose-fed rats.
Topics: Aldehyde Reductase; Animals; Cornea; Diet; Epithelium; Galactitol; Galactose; Male; Ophthalmic Solutions; Rats; Rats, Inbred Strains; Sugar Alcohol Dehydrogenases; Sugar Alcohols; Thiazoles; Thiazolidinediones | 1986 |
Statil-sensitive polyol formation in nerve of galactose-fed mice.
Topics: Aldehyde Reductase; Animals; Carbohydrates; Diabetes Mellitus, Experimental; Galactitol; Galactose; Inositol; Mice; Mice, Inbred C57BL; Peripheral Nerves; Phthalazines; Pyridazines; Sorbitol; Sugar Alcohol Dehydrogenases; Sugar Alcohols | 1988 |
Early morning urine galactitol levels in relation to galactose intake: a possible method of monitoring the diet in galactokinase deficiency.
Topics: Carbohydrate Metabolism, Inborn Errors; Diet; Female; Galactitol; Galactokinase; Galactose; Humans; Infant; Infant, Newborn; Male; Pregnancy; Sugar Alcohols; Time Factors | 1988 |
Prevention of sugar-induced cataractogenesis in rats by butylated hydroxytoluene.
Topics: Animals; Butylated Hydroxytoluene; Cataract; Galactitol; Galactose; Glutathione; Lens, Crystalline; Male; Organ Size; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1988 |
Effect of sodium iodate injection on the development of galactose cataract in the rat.
Topics: Animals; Cataract; Diet; Female; Galactitol; Galactose; Injections; Iodates; Iodine; Lens, Crystalline; Male; Microscopy, Electron; Potassium; Rats; Rats, Inbred Strains; Retina; Sodium | 1988 |
Dietary restriction of maternal lactose intake does not prevent accumulation of galactitol in the amniotic fluid of fetuses affected with galactosaemia.
Topics: Adult; Amniotic Fluid; Female; Galactitol; Galactose; Galactosemias; Humans; Lactose; Pregnancy; Pregnancy Complications; Sugar Alcohols | 1988 |
[Influence of glucose on the conversion of galactose into galactitol in the young adult].
Topics: Adult; Blood Glucose; Female; Galactitol; Galactose; Galactosemias; Glucose; Humans; Insulin; Male; Sugar Alcohols | 1986 |
Galactose metabolism in male and female rats. II. Eye-ball differences.
Topics: Animals; Aqueous Humor; Cataract; Dietary Carbohydrates; Female; Galactitol; Galactose; Galactosemias; Glucose; Lactose; Lens, Crystalline; Male; Rats | 1986 |
Galactose metabolism in male and female rats. I. Blood and urinary differences.
Topics: Animals; Dietary Carbohydrates; Female; Galactitol; Galactose; Glucose; Lactose; Male; Rats; Rats, Inbred Strains; Sex Factors | 1986 |
Galactose and galactitol in the urine of children with compound heterozygosity for Duarte variant and classical galactosemia (GtD/gt) after an oral galactose load.
Topics: Aging; Child; Child, Preschool; Galactitol; Galactose; Galactosemias; Heterozygote; Humans; Infant; Sugar Alcohols | 1985 |
Modelling cortical cataractogenesis VII: Effects of vitamin E treatment on galactose-induced cataracts.
Topics: Animals; Cataract; Galactitol; Galactose; In Vitro Techniques; Lens, Crystalline; Microscopy, Electron, Scanning; Rats; Rats, Inbred Strains; Vitamin E | 1985 |
Prevention of cataract development in severely galactosemic rats by the aldose reductase inhibitor, tolrestat.
Topics: Animals; Cataract; Dose-Response Relationship, Drug; Galactitol; Galactose; Galactosemias; Humans; Lens, Crystalline; Male; Naphthalenes; Rats | 1985 |
Influence of non utilizable carbohydrates on the utilization of glucose in the larval nutrition of Oryzaephilus mercator (Fauv.).
Topics: Animals; Arabinose; Dietary Carbohydrates; Galactitol; Galactose; Glucose; Insecta; Intestinal Absorption; Inulin; Lactose; Larva; Rhamnose; Sorbose; Starch; Xylose | 1973 |
Letter: Galactokinase deficiency in twins.
Topics: Adult; Cataract; Child, Preschool; Diseases in Twins; Female; Galactitol; Galactose; Humans; Phosphotransferases | 1974 |
The absence of cataracts in mice with congenital hyperglycemia.
Topics: Alcohol Oxidoreductases; Animals; Cataract; Diabetes Mellitus; Diet; Fructose; Galactitol; Galactose; Glucose; Glucosephosphate Dehydrogenase; Hexokinase; Hyperglycemia; Inositol; Lens, Crystalline; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Phosphogluconate Dehydrogenase | 1974 |
Galactitol accumulation and irreversible lens opacities in galactosemic rats.
Topics: Animals; Cataract; Dietary Carbohydrates; Galactitol; Galactose; Galactosemias; Lens, Crystalline; Male; Rats; Remission, Spontaneous; Sugar Alcohols; Time Factors | 1973 |
Urinary galactitol in galactosemic patients.
Topics: Diet; Dietary Proteins; Erythrocytes; Galactitol; Galactose; Galactosemias; Humans; Phosphates; Sugar Alcohols; Time Factors | 1973 |
P.M.R. spectroscopy of monomethyl ethers of D-galactopyranose and its derivatives.
Topics: Deuterium; Ethers; Galactitol; Galactose; Glycosides; Magnetic Resonance Spectroscopy; Pyrans; Solutions | 1971 |
Sugar cataracts in Mongolian gerbil (Meriones unguiculatus).
Topics: Aldehyde Reductase; Animals; Cataract; Disease Models, Animal; Galactitol; Galactose; Gerbillinae; Lens, Crystalline; Rats; Rats, Inbred Strains | 1983 |
Endoneurial blood flow and oxygen tension in the sciatic nerves of rats with experimental diabetic neuropathy.
Topics: Animals; Blood Flow Velocity; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Galactitol; Galactose; Male; Neural Conduction; Oxygen Consumption; Rats; Rats, Inbred Strains; Sciatic Nerve; Water-Electrolyte Balance | 1984 |
Protection against thermal cell death in Chinese hamster ovary cells by glucose, galactose, or mannose.
Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Female; Galactitol; Galactose; Glucose; Hot Temperature; Kinetics; Mannose; Ovary | 1984 |
A geographic approach to senile cataracts: possible links with milk consumption, lactase activity, and galactose metabolism.
Topics: Adult; Aged; Animals; Asia; beta-Galactosidase; Cataract; Dairy Products; Female; Galactitol; Galactose; Galactosidases; Humans; Infant; Infant, Newborn; Lactose; Male; Marsupialia; Middle Aged; Milk; Mutation; Rats | 1982 |
[Effect of prolonged consumption of lactose or hydrolyzed lactose in the rat. 2. Digestibility, retention and utilization of lactose components].
Topics: Animals; Diet; Digestion; Galactitol; Galactose; Glucose; Glycosuria; Hydrolysis; Lactose; Rats; Rats, Inbred Strains | 1982 |
An alternative route for D-galactose catabolism shared with that for dulcitol degradation route in mycobacteria.
Topics: Galactitol; Galactose; Hexoses; Mycobacteriaceae; Sugar Alcohols | 1981 |
Endothelial changes in galactose-fed dogs.
Topics: Animals; Cell Count; Cell Size; Diet; Dogs; Endothelium, Corneal; Galactitol; Galactose; Galactosemias; Male | 1995 |
Galactitol in galactosemia.
Topics: Age Factors; Galactitol; Galactose; Galactosemias; Humans; Infant | 1995 |
Demonstration that polyol accumulation is responsible for diabetic cataract by the use of transgenic mice expressing the aldose reductase gene in the lens.
Topics: Aldehyde Reductase; Animals; Blotting, Southern; Cataract; Crosses, Genetic; Diabetes Mellitus, Experimental; Diabetic Retinopathy; DNA, Complementary; Female; Galactitol; Galactose; Galactosemias; Genotype; Humans; Lens, Crystalline; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Polymerase Chain Reaction | 1995 |
Galactosemia produces ARI-preventable nodal changes similar to those of diabetic neuropathy.
Topics: Aldehyde Reductase; Animals; Axons; Body Weight; Diabetic Neuropathies; Fructose; Galactitol; Galactose; Galactosemias; Inositol; Microscopy, Electron; Nerve Fibers, Myelinated; Nerve Regeneration; Neural Conduction; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sorbitol; Sural Nerve | 1994 |
Galactose-induced retinal microangiopathy in rats.
Topics: Aldehyde Reductase; Animals; Basement Membrane; Capillaries; Cataract; Diabetic Retinopathy; Disease Models, Animal; Erythrocytes; Galactitol; Galactose; Galactosemias; Imidazoles; Imidazolidines; Male; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels; Sciatic Nerve | 1995 |
Polyol and water accumulation in muscle of galactose-fed rats.
Topics: Aldehyde Reductase; Animals; Diet; Galactitol; Galactose; Gene Expression; Male; Muscles; Polymers; Rats; Rats, Sprague-Dawley; Water | 1994 |
Blood sugar levels and renal sugar excretion after the intake of high carbohydrate diets in cats.
Topics: Animals; Blood Glucose; Carbohydrates; Cats; Dietary Carbohydrates; Female; Fructose; Galactitol; Galactose; Glucose; Glycosuria; Lactose; Male; Starch; Sucrose | 1994 |
Impairment of afferent arteriolar myogenic responsiveness in the galactose-fed rat.
Topics: Animals; Arterioles; Blood Pressure; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Diet; Disease Models, Animal; Galactitol; Galactose; Homeostasis; Hydronephrosis; Ibuprofen; In Vitro Techniques; Kidney; Male; Perfusion; Polymers; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1994 |
Aldose reductase inhibitors and galactose toxicity in neonatal and maternal rat lenses.
Topics: Aldehyde Reductase; Animals; Animals, Newborn; Cataract; Female; Galactitol; Galactose; Imidazoles; Imidazolidines; Lens, Crystalline; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Sprague-Dawley | 1993 |
Osmoregulatory alterations in myo-inositol uptake by bovine lens epithelial cells. Part 1: A hypertonicity-induced protein enhances myo-inositol transport.
Topics: Aldehyde Reductase; Animals; Biological Transport; Carrier Proteins; Cattle; Cells, Cultured; Cycloheximide; Epithelium; Galactitol; Galactose; Heat-Shock Proteins; Hypertonic Solutions; Imidazoles; Imidazolidines; Inositol; Lens, Crystalline; Membrane Proteins; Symporters; Water-Electrolyte Balance | 1994 |
Galactose-induced cataract formation in guinea pigs: morphologic changes and accumulation of galactitol.
Topics: Animals; Cataract; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; Galactitol; Galactose; Guinea Pigs; Inositol; Lens, Crystalline; Male; Rats | 1994 |
Suppression of pentosidine formation in galactosemic rat lens by an inhibitor of aldose reductase.
Topics: Aldehyde Reductase; Animals; Arginine; Ascorbic Acid; Diet; Female; Galactitol; Galactose; Galactosemias; Glutathione; Imidazoles; Imidazolidines; Lens, Crystalline; Lysine; Maillard Reaction; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
A physiological level of ascorbate inhibits galactose cataract in guinea pigs by decreasing polyol accumulation in the lens epithelium: a dehydroascorbate-linked mechanism.
Topics: Animals; Aqueous Humor; Ascorbic Acid; Cataract; Cells, Cultured; Dehydroascorbic Acid; Dogs; Female; Galactitol; Galactose; Glutathione; Guinea Pigs; Hydrogen Peroxide; Inositol; Lens, Crystalline; NADP; Sodium-Potassium-Exchanging ATPase | 1994 |
[Prefeeding of aldose reductase inhibitor inhibits galactose cataract].
Topics: Aldehyde Reductase; Animals; Cataract; Crystallins; Galactitol; Galactose; Premedication; Quinazolines; Rats; Rats, Sprague-Dawley | 1993 |
Effect of pregnancy on development of galactose-induced cataract in rat.
Topics: Animals; Cataract; Dietary Carbohydrates; Female; Galactitol; Galactose; Galactosemias; Incidence; Lens, Crystalline; Male; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley | 1993 |
Effects of galactose feeding on aldose reductase gene expression.
Topics: Aldehyde Reductase; Animals; Brain; Galactitol; Galactose; Gene Expression; Inositol; Kidney; Male; Muscles; Rats; Rats, Wistar; RNA, Messenger; Testis; Xylitol; Xylose | 1993 |
The effect of dietary fruits and vegetables on urinary galactitol excretion in galactose-1-phosphate uridyltransferase deficiency.
Topics: Adolescent; Adult; Diet; Erythrocytes; Female; Fruit; Galactitol; Galactose; Galactosemias; Galactosephosphates; Humans; UTP-Hexose-1-Phosphate Uridylyltransferase; Vegetables | 1993 |
N.m.r. spectroscopic studies of fucose-containing oligosaccharides derived from keratanase digestion of articular cartilage keratan sulphates. Influence of fucose residues on keratanase cleavage.
Topics: Acetylglucosamine; Animals; beta-Galactosidase; Carbohydrate Conformation; Carbohydrate Sequence; Cartilage, Articular; Cattle; Fucose; Galactitol; Galactose; Glycoside Hydrolases; Keratan Sulfate; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oligosaccharides; Pseudomonas | 1993 |
Galactosemic neuropathy in transgenic mice for human aldose reductase.
Topics: Aldehyde Reductase; Animals; Base Sequence; DNA Primers; Female; Galactitol; Galactose; Galactosemias; Gene Expression Regulation, Enzymologic; Mice; Mice, Transgenic; Molecular Sequence Data; Neural Conduction; Peripheral Nervous System Diseases; Sciatic Nerve | 1996 |
Inhibition of aldose reductase: 13C NMR studies in isolated peripheral nerve.
Topics: Aldehyde Reductase; Animals; Carbon Isotopes; Enzyme Inhibitors; Galactitol; Galactose; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Nitroparaffins; Rats; Rats, Wistar; Sciatic Nerve; Sulfones | 1995 |
Osmoregulatory alterations in myo-inositol uptake by bovine lens epithelial cells. Part 5. Mechanism of the myo-inositol efflux pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cattle; Cells, Cultured; Chloride Channels; Chlorides; Enzyme Inhibitors; Epithelial Cells; Epithelium; Galactitol; Galactose; Inositol; Isotonic Solutions; Lens, Crystalline; Niflumic Acid; Osmolar Concentration; Phloretin; Saline Solution, Hypertonic; Water-Electrolyte Balance | 1996 |
Diabetic-like retinopathy ameliorated with the aldose reductase inhibitor WAY-121,509.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Cataract; Diabetic Retinopathy; Erythrocytes; Female; Galactitol; Galactose; Glycated Hemoglobin; Image Processing, Computer-Assisted; Lens, Crystalline; Polymers; Random Allocation; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels | 1996 |
Impairment of afferent arteriolar myogenic responsiveness in the galactose-fed rat is prevented by tolrestat.
Topics: Aldehyde Reductase; Angiotensin II; Animals; Arterioles; Blood Pressure; Cohort Studies; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet; Disease Models, Animal; Enzyme Inhibitors; Galactitol; Galactose; Image Processing, Computer-Assisted; In Vitro Techniques; Kidney; Male; Muscle, Smooth, Vascular; Naphthalenes; Perfusion; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents | 1996 |
Glycolytic pathway, redox state of NAD(P)-couples and energy metabolism in lens in galactose-fed rats: effect of an aldose reductase inhibitor.
Topics: Aldehyde Reductase; Animals; Energy Metabolism; Enzyme Inhibitors; Galactitol; Galactose; Galactosemias; Gas Chromatography-Mass Spectrometry; Glycolysis; Inositol; Lens, Crystalline; Male; NADP; Naphthalenes; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1997 |
Effects of xylose on monkey lenses in organ culture: a model for study of sugar cataracts in a primate.
Topics: Animals; Cataract; Disease Models, Animal; Galactitol; Galactose; Glucose; Lens, Crystalline; Macaca mulatta; Organ Culture Techniques; Phosphorylcholine; Sorbitol; Xylitol; Xylose | 1998 |
Inhibition of galactose-induced cataractogenesis by troglitazone, a new antidiabetic drug with an antioxidant property, in rat lens culture.
Topics: Aldehyde Reductase; Animals; Antioxidants; Cataract; Chromans; Galactitol; Galactose; Glutathione Peroxidase; Glutathione Reductase; Hypoglycemic Agents; Lens, Crystalline; Lipid Peroxides; NADP; Organ Culture Techniques; Organ Size; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidinediones; Troglitazone; Vacuoles | 1999 |
Preventive effect of topical vitamin E-containing liposome instillation on the progression of galactose cataract. Comparison between 5-week- and 12-week-old rats fed a 25% galactose diet.
Topics: Animals; Body Water; Cataract; Disease Progression; Drug Carriers; Galactitol; Galactose; Glutathione; Lens, Crystalline; Lipid Peroxides; Liposomes; Male; Rats; Rats, Wistar; Vitamin E | 1999 |
Homogeneous bioluminescence assay for galactosuria: interference and kinetic analysis.
Topics: Adenosine Triphosphate; False Positive Reactions; Galactitol; Galactokinase; Galactose; Galactosemias; Humans; Kinetics; Luciferases; Luminescent Measurements; Sensitivity and Specificity; Sugar Acids | 1999 |
Cataract development in 12-month-old rats fed a 25% galactose diet and its relation to osmotic stress and oxidative damage.
Topics: Animals; Body Water; Cataract; Cholesterol; Crystallins; Diet; Galactitol; Galactose; Galactosemias; Glutathione; Lens, Crystalline; Lipid Peroxides; Male; Osmotic Pressure; Oxidative Stress; Rats; Rats, Wistar; Vitamin E | 1999 |
Subnormal retinal oxygenation response precedes diabetic-like retinopathy.
Topics: Animals; Blood Glucose; Carbon Dioxide; Diabetic Retinopathy; Fructose; Galactitol; Galactose; Galactosemias; Glucose; Inositol; Magnetic Resonance Imaging; Oxygen; Partial Pressure; Rats; Retina; Sorbitol | 1999 |
A new approach against sugar cataract through aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Enzyme Inhibitors; Galactitol; Galactose; Lens, Crystalline; Naphthalenes; Rats; Rats, Sprague-Dawley | 1999 |
Attenuation of sugar cataract by ethyl pyruvate.
Topics: Adenosine Triphosphate; Animals; Aqueous Humor; Cataract; Crystallins; Dietary Sucrose; Galactitol; Galactose; Galactosemias; Glycosylation; Male; Ophthalmic Solutions; Pyruvates; Rats; Rats, Sprague-Dawley | 1999 |
An aldose redutase inhibitor prevents the intimal thickening in coronary arteries of galactose-fed beagle dogs.
Topics: Aldehyde Reductase; Animals; Aorta; Blood Glucose; Body Weight; Coronary Vessels; Diabetic Angiopathies; Dogs; Enzyme Inhibitors; Erythrocytes; Galactitol; Galactose; Glycated Hemoglobin; Male; Polymers; Rhodanine; Thiazolidines | 1999 |
A mouse model of galactose-induced cataracts.
Topics: Aldehyde Reductase; Animals; Base Sequence; Cataract; Disease Models, Animal; DNA, Complementary; Galactitol; Galactokinase; Galactose; Gene Expression; Gene Targeting; Humans; Mice; Mice, Knockout; Mice, Transgenic; Molecular Sequence Data; Oxidation-Reduction | 2000 |
Preventive effect of vitamin E-containing liposome instillation on cataract progression in 12-month-old rats fed a 25% galactose diet.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Body Water; Cataract; Cholesterol; Diet; Disease Progression; Drug Carriers; Galactitol; Galactose; Galactosemias; Glutathione; Lens, Crystalline; Lipid Peroxides; Liposomes; Male; Phosphatidylcholines; Rats; Rats, Wistar; Vitamin E | 2000 |
Plasma galactose and galactitol concentration in patients with galactose-1-phosphate uridyltransferase deficiency galactosemia: determination by gas chromatography/mass spectrometry.
Topics: Adolescent; Adult; Child; Child, Preschool; Galactitol; Galactose; Galactosemias; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; UTP-Hexose-1-Phosphate Uridylyltransferase | 2000 |
The role of aldose reductase in sugar cataract formation: aldose reductase plays a key role in lens epithelial cell death (apoptosis).
Topics: Aldehyde Reductase; Animals; Apoptosis; Base Sequence; Cataract; Cells, Cultured; DNA Primers; Dogs; Enzyme Inhibitors; Epithelial Cells; Fluorenes; Galactitol; Galactose; Hydantoins; Lens, Crystalline; Sugar Alcohols | 2001 |
Galactose metabolism in normal human lymphoblasts studied by (1)H, (13)C and (31)P NMR spectroscopy of extracts.
Topics: Carbon Isotopes; Cell Extracts; Cells, Cultured; Galactitol; Galactose; Galactosephosphates; Humans; Hydrogen; Lymphocytes; Magnetic Resonance Spectroscopy; Phosphorus Isotopes; Uridine Diphosphate Galactose; Uridine Diphosphate Glucose | 2001 |
Osmoregulatory alterations in taurine uptake by cultured human and bovine lens epithelial cells.
Topics: Aldehyde Reductase; Animals; Biological Transport; Carrier Proteins; Cattle; Cells, Cultured; Epithelial Cells; Galactitol; Galactose; Humans; Imidazoles; Imidazolidines; Lens, Crystalline; Membrane Glycoproteins; Membrane Transport Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Taurine; Up-Regulation; Water-Electrolyte Balance | 2002 |
The in vitro effects of galactose and its derivatives on rat brain Mg2+-ATPase activity.
Topics: Animals; Animals, Suckling; Brain; Ca(2+) Mg(2+)-ATPase; Dose-Response Relationship, Drug; Enzyme Activation; Female; Galactitol; Galactose; Galactosephosphates; Glucose; Glucosephosphates; In Vitro Techniques; Male; Rats; Rats, Wistar | 2002 |
Apoptotic cell death in the lens epithelium of rat sugar cataract.
Topics: Aldehyde Reductase; Animals; Apoptosis; Blotting, Western; Cataract; DNA Fragmentation; Epithelial Cells; Galactitol; Galactose; Genes, p53; Imidazoles; Imidazolidines; In Situ Nick-End Labeling; Lens, Crystalline; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Protein p53 | 2003 |
[Effects of dulcitol and of mucic acid on calcium utilization].
Topics: Alcohols; Calcium; Calcium, Dietary; Galactitol; Galactose; Sugar Acids; Water-Electrolyte Balance | 1955 |
THE ISOLATION AND IDENTIFICATION OF GALACTITOL FROM THE URINE OF PATIENTS WITH GALACTOSEMIA.
Topics: Alcohols; Blood Chemical Analysis; Body Fluids; Carbohydrate Metabolism; Chromatography; Galactitol; Galactose; Galactosemias; Humans; Infant; Urine | 1964 |
The accumulation of dulcitol and water in rabbit lens incubated with galactose.
Topics: Alcohols; Animals; Galactitol; Galactose; Lens, Crystalline; Rabbits; Water | 1962 |
Osmotic changes caused by the accumulation of dulcitol in the lenses of rats fed with galactose.
Topics: Alcohols; Animals; Carbohydrate Metabolism; Galactitol; Galactose; Lens, Crystalline; Rats | 1962 |
Renal excretion of galactose and galactitol in patients with classical galactosaemia, obligate heterozygous parents and healthy subjects.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Female; Galactitol; Galactose; Galactosemias; Heterozygote; Humans; Kidney; Male; Middle Aged | 2003 |
The alternative D-galactose degrading pathway of Aspergillus nidulans proceeds via L-sorbose.
Topics: Aspergillus nidulans; Biomass; Chromatography, High Pressure Liquid; Galactitol; Galactose; Genes, Fungal; Hexokinase; Magnetic Resonance Spectroscopy; Mutation; Nitrates; Quaternary Ammonium Compounds; Sorbose; Sugar Alcohol Dehydrogenases | 2004 |
Stable-isotope dilution analysis of galactose metabolites in human erythrocytes.
Topics: Blood Chemical Analysis; Erythrocytes; Female; Galactitol; Galactose; Galactosemias; Galactosephosphates; Gas Chromatography-Mass Spectrometry; Humans; Isotope Labeling; Male; Metabolic Clearance Rate; Radioisotope Dilution Technique; Reproducibility of Results; Sensitivity and Specificity | 2003 |
Age dependence of endogenous galactose formation in Q188R homozygous galactosemic patients.
Topics: Adolescent; Adult; Age Factors; Body Height; Body Weight; Carbon Isotopes; Child; Child, Preschool; Galactitol; Galactose; Galactosemias; Humans; Infusion Pumps; Models, Biological; Mutation; Sugar Acids; UTP-Hexose-1-Phosphate Uridylyltransferase | 2004 |
Galactonate determination in urine by stable isotope dilution gas chromatography-mass spectrometry.
Topics: Adolescent; Adult; Carbon Isotopes; Child; Child, Preschool; Female; Galactitol; Galactose; Galactosemias; Gas Chromatography-Mass Spectrometry; Humans; Indicator Dilution Techniques; Lactones; Male; Quality Control; Sensitivity and Specificity; Sugar Acids | 2004 |
The galactokinase of Hypocrea jecorina is essential for cellulase induction by lactose but dispensable for growth on d-galactose.
Topics: Amino Acid Sequence; Binding Sites; Cellulase; Cloning, Molecular; Conserved Sequence; DNA, Fungal; Enzyme Induction; Galactitol; Galactokinase; Galactose; Gene Expression Regulation, Fungal; Genes, Fungal; Glucans; Hypocrea; Lactose; Membrane Glycoproteins; Molecular Sequence Data; Molecular Weight; Sequence Alignment; Sequence Analysis, DNA; UDPglucose-Hexose-1-Phosphate Uridylyltransferase | 2004 |
Protective effect of L-cysteine and glutathione on the modulated suckling rat brain Na+, K+, -ATPase and Mg2+ -ATPase activities induced by the in vitro galactosaemia.
Topics: Animals; Animals, Suckling; Antioxidants; Brain; Brain Diseases, Metabolic, Inborn; Ca(2+) Mg(2+)-ATPase; Cysteine; Drug Combinations; Drug Evaluation, Preclinical; Female; Galactitol; Galactose; Galactosemias; Galactosephosphates; Glutathione; Male; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase | 2004 |
Ophthalmoscopic and morphogenetic changes in rat lens induced by galactose: attenuation by pyruvate.
Topics: Animals; Cataract; Cell Differentiation; Cell Movement; Diet; Galactitol; Galactose; Lens, Crystalline; Ophthalmoscopy; Oxidative Stress; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2004 |
High tolerance for oral galactose in classical galactosaemia: dietary implications.
Topics: Administration, Oral; Adolescent; Drug Tolerance; Female; Fruit; Galactitol; Galactose; Galactosemias; Galactosephosphates; Humans; Male; Vegetables | 2004 |
Mg2+-ATPase activity in suckling rat brain regions in galactosaemia in vitro. L-Cysteine and glutathione effects.
Topics: Animals; Animals, Suckling; Antioxidants; Brain; Ca(2+) Mg(2+)-ATPase; Cysteine; Drug Combinations; Enzyme Activation; Female; Galactitol; Galactose; Galactosemias; Galactosephosphates; Glutathione; Male; Rats; Rats, Wistar | 2005 |
Suckling rat brain regional distribution of Na+,K+-atpase activity in the in vitro galactosaemia: the effect of L-cysteine and glutathione.
Topics: Animals; Animals, Suckling; Antioxidants; Brain; Brain Chemistry; Cysteine; Disease Models, Animal; Enzyme Activation; Female; Free Radicals; Galactitol; Galactose; Galactosemias; Galactosephosphates; Glutathione; In Vitro Techniques; Male; Oxidative Stress; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Subcellular Fractions | 2005 |
D-Galactose induces cellulase gene expression in Hypocrea jecorina at low growth rates.
Topics: Artificial Gene Fusion; Blotting, Western; Cellulase; Cellulose 1,4-beta-Cellobiosidase; Culture Media; Fungal Proteins; Galactitol; Galactose; Gene Expression Regulation, Fungal; Glucose; Hypocrea; Lactose | 2006 |
Synthesis of alpha-D-Gal f-(1-->2)-D-galactitol and alpha-D-Gal f-(1-->2)[beta-D-Gal f-(1-->3)]-D-galactitol, oligosaccharide derivatives from Bacteroides cellulosolvens glycoproteins.
Topics: Bacteroides; Carbohydrate Sequence; Galactitol; Galactose; Glycoproteins; Indicators and Reagents; Models, Molecular; Molecular Sequence Data; Trisaccharides | 2006 |
Two familial cases of high blood galactose of unknown aetiology.
Topics: Carbohydrate Metabolism, Inborn Errors; Cell Membrane; Chromosomes, Human, X; Family Health; Galactitol; Galactose; Galactosemias; Galactosephosphates; Humans; Infant, Newborn; Lactose; Male | 2006 |
Induction of extracellular beta-galactosidase (Bga1) formation by D-galactose in Hypocrea jecorina is mediated by galactitol.
Topics: beta-Galactosidase; Culture Media; Fungal Proteins; Galactitol; Galactose; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Glucose; Hypocrea | 2007 |
Xyr1 receives the lactose induction signal and regulates lactose metabolism in Hypocrea jecorina.
Topics: Aldehyde Reductase; beta-Galactosidase; Enzyme Activation; Fungal Proteins; Galactitol; Galactose; Gene Expression Regulation, Fungal; Hypocrea; Lactose; Transcription Factors; Transcription, Genetic; Xylosidases | 2007 |
Structural and functional characterization of galactooligosaccharides in Nostoc commune: beta-D-galactofuranosyl-(1-->6)-[beta-D-galactofuranosyl-(1-->6)]2-beta-D-1,4-anhydrogalactitol and beta-(1-->6)-galactofuranosylated homologues.
Topics: alpha-Amylases; Animals; Carbohydrate Sequence; Chromatography, Ion Exchange; Chromatography, Thin Layer; Desiccation; Escherichia coli; Furans; Galactitol; Galactose; Hot Temperature; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Nostoc commune; Oligosaccharides; Phosphoglucomutase; Rabbits; Sucrose; Temperature; Trehalose | 2007 |
Synthesis and X-ray crystal structures of two transition metal complexes based on functionalised 1,5-anhydro-2-deoxy-D-galactitol and methyl 2-deoxy-alpha-D-galactopyranoside.
Topics: Carbohydrate Conformation; Crystallization; Crystallography, X-Ray; Deoxy Sugars; Galactitol; Galactose; Ligands; Organometallic Compounds; Transition Elements | 2008 |
The roles of galactitol, galactose-1-phosphate, and phosphoglucomutase in galactose-induced toxicity in Saccharomyces cerevisiae.
Topics: Culture Media; Galactitol; Galactokinase; Galactose; Galactosephosphates; Multienzyme Complexes; Phosphoglucomutase; Plasmids; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Trans-Activators | 2008 |
Diagnosis of inherited disorders of galactose metabolism.
Topics: Carbohydrate Metabolism, Inborn Errors; DNA Mutational Analysis; DNA Primers; Galactitol; Galactokinase; Galactose; Galactosemias; Galactosephosphates; Genetics, Medical; Humans; Infant, Newborn; Neonatal Screening; Polymerase Chain Reaction; UDPglucose 4-Epimerase; UTP-Hexose-1-Phosphate Uridylyltransferase | 2008 |
DFT/MM modeling of the five-membered ring in 3,6-anhydrogalactose derivatives and its influence on disaccharide adiabatic maps.
Topics: Carbohydrate Conformation; Crystallography, X-Ray; Disaccharides; Galactitol; Galactose; Glycosides; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Molecular Structure; Quantum Theory; Reproducibility of Results; Software | 2008 |
Elevated lipid peroxidation and DNA oxidation in nerve from diabetic rats: effects of aldose reductase inhibition, insulin, and neurotrophic factors.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; DNA; Enzyme Inhibitors; Female; Galactitol; Galactose; Hydrazones; Hypoglycemic Agents; Insulin; Lipid Peroxidation; Malondialdehyde; Nerve Growth Factors; Neurons; Nitroparaffins; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sulfones | 2008 |
Biochemical monitoring of pregnancy and breast feeding in five patients with classical galactosaemia--and review of the literature.
Topics: Adult; Breast Feeding; Cesarean Section; Erythrocytes; Female; Galactitol; Galactose; Galactosemias; Galactosephosphates; Humans; Lactation; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Young Adult | 2009 |
Duarte (DG) galactosemia: a pilot study of biochemical and neurodevelopmental assessment in children detected by newborn screening.
Topics: Child; Child Development; Child, Preschool; Female; Galactitol; Galactose; Galactosemias; Humans; Infant; Infant, Newborn; Longitudinal Studies; Male; Neonatal Screening; Pilot Projects | 2008 |
Outcomes of siblings with classical galactosemia.
Topics: Adolescent; Adult; Birth Order; Brain; Child; Child, Preschool; Diet Records; Female; Galactitol; Galactose; Galactosemias; Galactosephosphates; Humans; Infant; Intelligence Tests; Ireland; Lactose; Language Disorders; Magnetic Resonance Spectroscopy; Male; Neurologic Examination; Patient Compliance; Retrospective Studies; Siblings; Young Adult | 2009 |
Polyol formation in cell lines of rat retinal capillary pericytes and endothelial cells (TR-rPCT and TR-iBRB).
Topics: Actins; Aldehyde Reductase; Animals; Apoptosis; Capillaries; Cells, Cultured; Endothelial Cells; Galactitol; Galactose; Glucose; In Situ Nick-End Labeling; Indoles; L-Iditol 2-Dehydrogenase; Pericytes; Rats; Rats, Transgenic; Retina; Retinal Vessels; Sorbitol; Staining and Labeling; Sugar Alcohols; von Willebrand Factor | 2009 |
Single-step bioconversion for the preparation of L-gulose and L-galactose.
Topics: Apium; Bioengineering; Enzyme Stability; Escherichia coli; Galactitol; Galactose; Hexoses; Kinetics; Mannitol Dehydrogenases; Recombinant Proteins; Sorbitol; Stereoisomerism | 2010 |
Oxidative stress in lens in vivo: inhibitory effect of caffeine. A preliminary report.
Topics: Adenosine Triphosphate; Animals; Caffeine; Cataract; Galactitol; Galactose; Glutathione; Lens, Crystalline; Organ Size; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2010 |
Duarte galactosemia: how sweet is it?
Topics: Child; Child, Preschool; Dietary Carbohydrates; Galactitol; Galactose; Galactosemias; Galactosephosphates; Humans; Infant; Sugar Acids | 2010 |
Monitoring of biochemical status in children with Duarte galactosemia: utility of galactose, galactitol, galactonate, and galactose 1-phosphate.
Topics: Child; Child, Preschool; Dietary Carbohydrates; Erythrocytes; Female; Galactitol; Galactose; Galactosemias; Galactosephosphates; Humans; Infant; Male; Monitoring, Physiologic; Reference Values; Sugar Acids | 2010 |
Features and outcome of galactokinase deficiency in children diagnosed by newborn screening.
Topics: Bosnia and Herzegovina; Emigration and Immigration; Female; Galactitol; Galactose; Galactosemias; Germany; Homozygote; Humans; Incidence; Infant, Newborn; Male; Mutation; Neonatal Screening; Serbia; Treatment Outcome | 2011 |
Long-term complications in Estonian galactosemia patients with a less strict lactose-free diet and metabolic control.
Topics: Adolescent; Child; Diet; Estonia; Female; Galactitol; Galactose; Galactosemias; Genotype; Humans; Lactose; Male; Phenotype; Retrospective Studies | 2011 |
Identification of the galactitol dehydrogenase, LadB, that is part of the oxido-reductive D-galactose catabolic pathway in Aspergillus niger.
Topics: Alcohol Oxidoreductases; Aspergillus niger; Galactitol; Galactose; Gene Expression Regulation, Fungal; Hexoses; Ketoses; Metabolic Networks and Pathways; Metabolism; Oxidation-Reduction; Saccharomyces cerevisiae; Sugar Alcohol Dehydrogenases; Xylose | 2012 |
Early diet impacts infant rhesus gut microbiome, immunity, and metabolism.
Topics: Amino Acids; Animals; Animals, Newborn; Bottle Feeding; Breast Feeding; Cytokines; Feces; Female; Galactitol; Galactose; Humans; Infant; Infant Formula; Insulin; Lactobacillus; Macaca mulatta; Magnetic Resonance Spectroscopy; Male; Metabolomics; Microbiota; Ruminococcus | 2013 |
Polyol effects on growth factors and MAPK signaling in rat retinal capillary cells.
Topics: Aldehyde Reductase; Animals; Capillaries; Cell Line; Endothelial Cells; Fluorenes; Galactitol; Galactose; Glucose; Hydantoins; Intercellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Naphthalenes; Pericytes; Rats; Rats, Transgenic; Retinal Vessels; Sorbitol | 2014 |
Aldose reductase inhibitor counteracts the enhanced expression of matrix metalloproteinase-10 and improves corneal wound healing in galactose-fed rats.
Topics: Administration, Oral; Administration, Topical; Aldehyde Reductase; Animals; Corneal Dystrophies, Hereditary; Diabetes Mellitus, Experimental; Diet; Enzyme Inhibitors; Epithelium, Corneal; Galactitol; Galactose; Gene Expression Regulation; Integrin alpha3; Male; Matrix Metalloproteinase 10; Rats; Rats, Sprague-Dawley; Signal Transduction; Wound Healing | 2013 |
Efficient method for the conversion of agricultural waste into sugar alcohols over supported bimetallic catalysts.
Topics: Agriculture; Alcohols; Arabinose; Bioreactors; Biotechnology; Carbon; Catalysis; Fructose; Galactans; Galactitol; Galactose; Glucose; Hydrogen; Inulin; Mannitol; Microscopy, Electron, Transmission; Platinum; Sorbitol; Sugar Alcohols; Temperature; Tin; Triticum; Waste Products; X-Ray Diffraction; Xylans; Xylitol; Xylose | 2015 |
Galactose and its Metabolites Deteriorate Metaphase II Mouse Oocyte Quality and Subsequent Embryo Development by Disrupting the Spindle Structure.
Topics: Animals; Embryonic Development; Galactitol; Galactose; Galactosephosphates; Metaphase; Mice; Oocytes; Spindle Apparatus | 2017 |
Assessment of lactase activity in humans by measurement of galactitol and galactonate in serum and urine after milk intake.
Topics: Adult; Animals; Biomarkers; Dairy Products; Digestion; Galactitol; Galactose; Genotype; Humans; Lactase; Lactose; Lactose Intolerance; Liver; Male; Milk; Nutrition Assessment; Polymorphism, Single Nucleotide; Postprandial Period; Sugar Acids; Young Adult | 2019 |
Novel Mutation in GALT Gene in Galactosemia Patient with Group B Streptococcus Meningitis and Acute Liver Failure.
Topics: Child, Preschool; Developed Countries; Female; Follow-Up Studies; Galactitol; Galactose; Galactosemias; Humans; Infant, Newborn; Lactose Tolerance Test; Liver Failure, Acute; Magnetic Resonance Spectroscopy; Meningitis, Bacterial; Mutation; Neonatal Screening; Romania; Streptococcal Infections; Streptococcus; UTP-Hexose-1-Phosphate Uridylyltransferase | 2019 |
β-Galactosidase therapy can mitigate blood galactose elevation after an oral lactose load in galactose mutarotase deficiency.
Topics: beta-Galactosidase; Carbohydrate Epimerases; Cataract; Galactitol; Galactose; Galactosemias; Humans; Lactose | 2022 |
Biocatalytic conversion of a lactose-rich dairy waste into D-tagatose, D-arabitol and galactitol using sequential whole cell and fermentation technologies.
Topics: Escherichia coli; Fermentation; Galactitol; Galactose; Hexoses; Lactose; Sugar Alcohols; Sugars; Whey Proteins | 2022 |
Diabetic retinopathy: is it a consequence of hyperglycaemia?
Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Dogs; Galactitol; Galactosemias; Hexoses; Hyperglycemia; Retina | 1985 |
13C nuclear magnetic resonance spectra and the tautomeric equilibria of ketohexoses in solution.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Fructose; Furans; Galactitol; Hexoses; Isomerism; Ketoses; Magnetic Resonance Spectroscopy; Mannitol; Molecular Conformation; Pyrans; Sorbose; Stereoisomerism; Sugar Alcohols | 1974 |
The genes and enzymes for the catabolism of galactitol, D-tagatose, and related carbohydrates in Klebsiella oxytoca M5a1 and other enteric bacteria display convergent evolution.
Topics: Acetylgalactosamine; Amino Acid Sequence; Biological Evolution; Enterobacteriaceae; Escherichia coli; Galactitol; Galactosamine; Gene Transfer, Horizontal; Genes, Bacterial; Hexoses; Klebsiella oxytoca; Molecular Sequence Data; Phosphotransferases; Recombination, Genetic | 2004 |
Galactitol catabolism in Sinorhizobium meliloti is dependent on a chromosomally encoded sorbitol dehydrogenase and a pSymB-encoded operon necessary for tagatose catabolism.
Topics: ATP-Binding Cassette Transporters; Bacterial Proteins; Chromosomes, Bacterial; Fructose-Bisphosphate Aldolase; Galactitol; Gene Expression Regulation, Bacterial; Hexoses; L-Iditol 2-Dehydrogenase; Operon; Phylogeny; Plasmids; Sinorhizobium meliloti | 2019 |
L-Xylo-3-hexulose, a new rare sugar produced by the action of acetic acid bacteria on galactitol, an exception to Bertrand Hudson's rule.
Topics: Acetic Acid; Bacterial Proteins; Galactitol; Gluconobacter; Hexoses; Ketoses; Oxidation-Reduction; Oxidoreductases; PQQ Cofactor | 2021 |