Page last updated: 2024-08-22

galactosamine and acetaminophen

galactosamine has been researched along with acetaminophen in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (14.52)	18.7374
1990's	21 (33.87)	18.2507
2000's	14 (22.58)	29.6817
2010's	15 (24.19)	24.3611
2020's	3 (4.84)	2.80

Authors

Authors	Studies
Chen, H; Cui, BS; Ferreira, D; Hamann, MT; Han, SW; Li, S; Sun, H; Wang, XJ	1
Obermeier, F; Siegers, CP; Strubelt, O	1
Conti, M; Magistretti, MJ; Malandrino, S	1
Ding, Y; Huang, DK; Shen, JP; Zhang, XL; Zhang, YD; Zhu, SH	1
Ansari, RA; Dhawan, BN; Patnaik, GK; Tripathi, SC	1
Hickman, R; Terblanche, J	1
Shen, J	1
Handa, SS; Sharma, A	1
Wendel, A; Werner, C	1
Dozeman, R; Zieve, L	1
Zieve, L	1
Castell, JV; Donato, T; Gómez-Lechón, MJ; Larrauri, A; López, P; Montoya, A	1
Drenska, D; Klouchek, E; Ovcharov, R; Popov, A	1
Cho, C; Coulson, R; Linscheer, WG; Raheja, KL	1
Wardle, EN; Williams, R	1
Jollow, DJ; Price, V; Roberts, S; Smith, C	1
Bolanowska, W; Gessner, T	1
Hooser, SB; Rosengren, RJ; Sauer, JM; Sipes, IG	1
Lin, CC; Tsai, CC; Yen, MH	1
Klouchek, E; Markov, M; Popov, A	1
Raiford, DS; Thigpen, MC	1
Lin, CC; Lin, SC; Lin, YH; Shyuu, SJ	1
Chen, CH; Lin, CC; Lin, SC; Lin, YH	1
Lin, CC; Lin, SC; Lin, YH; Pan, SL; Supriyatna, S	1
Fariss, MW; Lippman, HR; Mumaw, VR; Ray, SD	1
Lin, CC; Shieh, DE; Yen, MH	1
Chrungoo, VJ; Singh, J; Singh, K	2
Mishra, SH; Rao, KS	1
Handa, SS; Karan, M; Vasisht, K	1
Lai, TY; Lin, WC; Wu, YW	1
Hayes, PC; Nelson, LJ; Newsome, PN; Plevris, JN	1
Bhattacharyya, P; Datta, S	1
Bangert, K; Bisgaard, HC; Ott, P; Tygstrup, N	1
Filipponi, F; Mosca, F	1
Bachleda, P; Dvorák, Z; Kosina, P; Simánek, V; Ulrichová, J; Walterová, D	1
Besra, SE; Chakravorty, AK; Das, B; Das, M; Ganguly, DK; Gomes, A; Sur, P; Vedasiromoni, JR	1
Ma, M; Purcell, WM; Xu, J	2
Kamiya, T; Nakagiri, R; Oda, H	1
Chamuleau, RA; Hoekstra, R; van de Kerkhove, MP; van Gulik, TM	1
Chandan, BK; Prabhakar, A; Qazi, GN; Singh, B; Singh, J; Taneja, SC	1
Adeyemo, O; Hanig, JP; Knapton, A; Miller, TJ; Noory, L; Weaver, J	1
Alvarez, M; Culebras, JM; González-Gallego, J; Tuñón, MJ	1
Balsari, A; Cardani, D; Dusio, GF; Gariboldi, S; Marcucci, F; Mauro, V; Palazzo, M; Rumio, C; Zanobbio, L	1
Egashira, Y; Lu, J; Ren, DF; Sanada, H; Wang, JZ	1
Andersen, ME; Brees, DJ; Loy, J; Singh, R; Thomas, RS; Watkins, PB; Wetmore, BA	1
Akachi, T; Kawagishi, H; Kawaguchi, T; Mori, M; Morita, T; Ohishi, Y; Shiina, Y; Sugiyama, K	1
Cavar, I; Culo, F; Kelava, T	1
Farhood, A; Jaeschke, H; Koerner, MR; Lampe, JN; Williams, CD	1
Daniele, SM; Lardizábal, MN; Nocito, AL; Ornella, LA; Palatnik, JF; Veggi, LM	1
Apers, S; Arcoraci, T; Breynaert, A; Fransen, E; Hermans, N; Kanyanga, C; Magielse, J; Pieters, L; van Dooren, I; Van Hoof, V; Vlietinck, A	1
Bame, JR; Erez-Roman, R; Futerman, AH; Kogot-Levin, A; Merrill, AH; Park, JW; Park, WJ; Pewzner-Jung, Y; Saada, A; Tirosh, B	1
Delgado, M; Garrido, F; Pacheco, M; Pajares, MA; Partearroyo, T; Pérez-Miguelsanz, J; Pérez-Sala, D	1
Jin, T; Liu, J; Shi, JS; Tao, N; Wu, Q; Zhang, D; Zhu, QN	1
Abe, K; Inakuma, T; Ishijima, T; Nakai, Y; Suganuma, H; Ushida, Y; Yajima, N; Yoshida, K	1
Jaeschke, H; Maes, M; Vinken, M	1
Dai, R; Dai, T; Deng, J; Huang, L; Jia, Y; Jiang, J; Xie, S; Zou, S	1
Aghajan, M; Kaplowitz, N; Min, RW; Than, TA; Win, S	1
Aghajan, M; Kaplowitz, N; Le, K; Min, RWM; Than, TA; Win, S; Zhang, J; Zhou, S	1
Chen, L; Chen, X; Jiang, H; Li, L; Lv, L; Wang, K; Wang, Q; Yan, R	1
Ding, Y; Ge, Y; Sun, Z; Tong, Z; Wang, W; Xu, Q; Zhang, S; Zhou, H; Zhou, L	1

Reviews

6 review(s) available for galactosamine and acetaminophen

Article	Year
Animal models of fulminant hepatic failure. Digestive diseases and sciences, 1991, Volume: 36, Issue:6 Topics: Acetaminophen; Animals; Carbon Tetrachloride Poisoning; Disease Models, Animal; Galactosamine; Hepatectomy; Hepatic Artery; Hepatic Encephalopathy; Liver Diseases; Portacaval Shunt, Surgical	1991
[Current status of the study of mechanisms of liver injury caused by some commonly used hepatotoxic agents]. Sheng li ke xue jin zhan [Progress in physiology], 1990, Volume: 21, Issue:1 Topics: Acetaminophen; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Galactosamine	1990
Animal models of fulminant hepatic failure: a critical evaluation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2000, Volume: 6, Issue:1 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Disease Models, Animal; Dogs; Galactosamine; Humans; Liver Failure; Mice; Rabbits; Swine	2000
Large animal models of fulminant hepatic failure in artificial and bioartificial liver support research. Biomaterials, 2004, Volume: 25, Issue:9 Topics: Acetaminophen; Animals; Disease Models, Animal; Dogs; Galactosamine; Guidelines as Topic; Hepatectomy; Liver; Liver Failure; Liver, Artificial; Research Design; Swine; Tissue Engineering	2004
An overview of animal models for investigating the pathogenesis and therapeutic strategies in acute hepatic failure. World journal of gastroenterology, 2009, Jul-07, Volume: 15, Issue:25 Topics: Acetaminophen; Animals; Carbon Tetrachloride; Disease Models, Animal; Galactosamine; Hepatectomy; Humans; Liver Failure, Acute; Liver Regeneration	2009
Experimental models of hepatotoxicity related to acute liver failure. Toxicology and applied pharmacology, 2016, Jan-01, Volume: 290 Topics: Acetaminophen; Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Concanavalin A; Disease Models, Animal; Fas Ligand Protein; Galactosamine; Humans; Liver Failure, Acute	2016

Other Studies

56 other study(ies) available for galactosamine and acetaminophen

Article	Year
Hepatoprotective Glucosyloxybenzyl 2-Hydroxy-2-isobutylsuccinates from Journal of natural products, 2021, 03-26, Volume: 84, Issue:3 Topics: Acetaminophen; Cell Survival; China; Hep G2 Cells; Humans; Molecular Structure; Orchidaceae; Phytochemicals; Protective Agents; Succinates	2021
The influence of ethanol pretreatment on the effects of nine hepatotoxic agents. Acta pharmacologica et toxicologica, 1978, Volume: 43, Issue:3 Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Alcoholic Intoxication; Amanitins; Aniline Hydroxylase; Animals; Aspartate Aminotransferases; Bromobenzenes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Ethanol; Galactosamine; Glutathione; Humans; L-Iditol 2-Dehydrogenase; Liver; Male; Mice; Microsomes, Liver; Organ Size; Phalloidine; Praseodymium; Thioacetamide	1978
Protective activity of silipide on liver damage in rodents. Japanese journal of pharmacology, 1992, Volume: 60, Issue:4 Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Ethanol; Female; Galactosamine; Male; Phosphatidylcholines; Praseodymium; Rats; Rats, Sprague-Dawley; Rats, Wistar; Silymarin	1992
[Effects of astragalus (ASI, SK) on experimental liver injury]. Yao xue xue bao = Acta pharmaceutica Sinica, 1992, Volume: 27, Issue:6 Topics: Acetaminophen; Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Galactosamine; Glucosides; Glutathione; Male; Malondialdehyde; Mice; Microsomes, Liver; Rats; Saponins; Triterpenes	1992
Antihepatotoxic properties of picroliv: an active fraction from rhizomes of Picrorhiza kurrooa. Journal of ethnopharmacology, 1991, Volume: 34, Issue:1 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cinnamates; Galactosamine; Glycosides; India; Liver; Liver Function Tests; Male; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred Strains; Silymarin; Vanillic Acid	1991
Hepatoprotective activity of andrographolide against galactosamine & paracetamol intoxication in rats. The Indian journal of medical research, 1990, Volume: 92 Topics: Acetaminophen; Animals; Disease Models, Animal; Diterpenes; Female; Galactosamine; Hepatitis, Animal; Liver; Liver Function Tests; Male; Naphthols; Plant Extracts; Rats	1990
Hepatic uptake and antihepatotoxic properties of vitamin E and liposomes in the mouse. Chemico-biological interactions, 1990, Volume: 75, Issue:1 Topics: Acetaminophen; Animals; Benzo(a)pyrene; Chemical and Drug Induced Liver Injury; Drug Carriers; Galactosamine; Lipopolysaccharides; Liposomes; Liver; Male; Mice; Phosphatidylcholines; Vitamin E	1990
Effect of hepatic failure toxins on regenerative enzymes in the liver after injury with galactosamine in the rat. The Journal of laboratory and clinical medicine, 1989, Volume: 113, Issue:4 Topics: Acetaminophen; Ammonium Chloride; Animals; Caprylates; Chemical and Drug Induced Liver Injury; Disulfides; Galactosamine; Hepatic Encephalopathy; Liver Diseases; Liver Regeneration; Male; Ornithine Decarboxylase Inhibitors; Rats; Rats, Inbred Strains; Thymidine Kinase; Time Factors	1989
Regenerative enzyme activity of the liver after partial hepatectomy or toxic injury depressed by continuous NH4+ infusion. The Journal of laboratory and clinical medicine, 1989, Volume: 114, Issue:5 Topics: Acetaminophen; Ammonia; Ammonium Chloride; Animals; Chemical and Drug Induced Liver Injury; Galactosamine; Hepatectomy; Liver; Liver Regeneration; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Rats; Rats, Inbred Strains; Thymidine Kinase	1989
The potential use of cultured hepatocytes in predicting the hepatotoxicity of xenobiotics. Xenobiotica; the fate of foreign compounds in biological systems, 1988, Volume: 18, Issue:6 Topics: Acetamides; Acetaminophen; Amanitins; Animals; Cells, Cultured; Drug Evaluation, Preclinical; Galactosamine; Kinetics; Liver; Microscopy, Electron; Orotic Acid; Rats; Rats, Inbred Strains; Thioacetamide	1988
[Experimental research on the hepatoprotective activity of drug combinations]. Eksperimentalna meditsina i morfologiia, 1985, Volume: 24, Issue:1 Topics: Acetaminophen; Amino Acids; Animals; Catechin; Chemical and Drug Induced Liver Injury; Drug Combinations; Drug Evaluation, Preclinical; Drug Synergism; Galactosamine; Liver; Male; Piracetam; Rats; Rats, Inbred Strains; Vitamins	1985
Failure of exogenous prostaglandin to afford complete protection against acetaminophen-induced hepatotoxicity in the rat. Journal of toxicology and environmental health, 1985, Volume: 15, Issue:3-4 Topics: Acetaminophen; Animals; Carbon Tetrachloride; Galactosamine; Gastric Mucosa; Liver; Male; Prostaglandins; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains	1985
Raised serum biliverdin in hepatic necrosis. Biochemical medicine, 1981, Volume: 26, Issue:1 Topics: Acetaminophen; Animals; Bile Acids and Salts; Bilirubin; Biliverdine; Chemical and Drug Induced Liver Injury; Cholestasis; Galactosamine; Humans; Liver; Liver Diseases; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Rats	1981
Biochemical basis for dose response relationships in reactive metabolite toxicity. Advances in experimental medicine and biology, 1981, Volume: 136 Pt A Topics: Acetaminophen; Animals; Biotransformation; Cricetinae; Diabetes Mellitus, Experimental; Drug-Related Side Effects and Adverse Reactions; Galactosamine; Kinetics; Liver; Models, Biological; Pharmaceutical Preparations; Salicylates	1981
Drug interactions with acetaminophen: effects of phenobarbital, prednisone and 5-fluorouracil in normal and tumor-bearing rats. Biochemical pharmacology, 1980, Apr-15, Volume: 29, Issue:8 Topics: Acetaminophen; Animals; Colonic Neoplasms; Drug Interactions; Female; Fluorouracil; Galactosamine; Inactivation, Metabolic; Liver Neoplasms, Experimental; Male; Neoplasms, Experimental; Phenobarbital; Prednisolone; Prednisone; Rats; Rats, Inbred ACI	1980
The interactions between retinol and five different hepatotoxicants in the Swiss Webster mouse. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1995, Volume: 25, Issue:2 Topics: 1-Propanol; Acetaminophen; Animals; Carbon Tetrachloride; Diterpenes; Drug Interactions; Drug Synergism; Galactosamine; Liver; Male; Mice; Phalloidine; Propanols; Retinoids; Retinyl Esters; Transaminases; Vitamin A	1995
The evaluation of hepatoprotective effects of Taiwan folk medicine 'teng-khia-u'. Journal of ethnopharmacology, 1995, Volume: 45, Issue:2 Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Division; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Galactosamine; Liver; Liver Diseases; Lymphocytes; Male; Medicine, Traditional; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Taiwan	1995
[A pharmacological study of the hepatoprotective activity of fructose-1,6-diphosphate]. Eksperimentalna meditsina i morfologiia, 1993, Volume: 31, Issue:3-4 Topics: Acetaminophen; Animals; Dose-Response Relationship, Drug; Drug Interactions; Fructosediphosphates; Galactosamine; Immunologic Factors; Liver; Male; Rats; Rats, Wistar	1993
Kupffer cell stimulation with Corynebacterium parvum reduces some cytochrome P450-dependent activities and diminishes acetaminophen and carbon tetrachloride-induced liver injury in the rat. Toxicology and applied pharmacology, 1994, Volume: 129, Issue:1 Topics: Acetaminophen; Alanine Transaminase; Animals; Biotransformation; Carbon Tetrachloride; Cells, Cultured; Coumarins; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Galactosamine; Glutathione; Immunization; Kupffer Cells; Liver; Male; Microsomes, Liver; Nitrophenols; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Propionibacterium acnes; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence	1994
Hepatoprotective effects of Taiwan folk medicine: wedelia chinensis on three hepatotoxin-induced hepatotoxicity. The American journal of Chinese medicine, 1994, Volume: 22, Issue:2 Topics: Acetaminophen; Acute Disease; Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drugs, Chinese Herbal; Galactosamine; Liver; Male; Mice; Mice, Inbred ICR; Microscopy, Fluorescence; Paraffin Embedding; Random Allocation; Rats; Rats, Wistar; Taiwan	1994
Protective and therapeutic effects of ban-zhi-lian on hepatotoxin-induced liver injuries. The American journal of Chinese medicine, 1994, Volume: 22, Issue:1 Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Galactosamine; Liver; Male; Mice; Mice, Inbred ICR; Rats; Rats, Wistar	1994
The protective effect of Alstonia scholaris R. Br. on hepatotoxin-induced acute liver damage. The American journal of Chinese medicine, 1996, Volume: 24, Issue:2 Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Dose-Response Relationship, Drug; Ethanol; Galactosamine; Injections, Intraperitoneal; Liver; Male; Medicine, Traditional; Mice; Plant Extracts; Rats; Rats, Wistar; Transaminases	1996
Cholesteryl hemisuccinate treatment protects rodents from the toxic effects of acetaminophen, adriamycin, carbon tetrachloride, chloroform and galactosamine. Toxicology letters, 1997, Feb-07, Volume: 90, Issue:2-3 Topics: Acetaminophen; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chloroform; Cholesterol Esters; Doxorubicin; Galactosamine; Heart Diseases; Liver Diseases; Male; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley	1997
Hepatoprotective effect of the fractions of Ban-zhi-lian on experimental liver injuries in rats. Journal of ethnopharmacology, 1997, Volume: 56, Issue:3 Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Galactosamine; Glycyrrhetinic Acid; Glycyrrhizic Acid; Liver; Male; Medicine, East Asian Traditional; Plant Extracts; Rats; Rats, Wistar; Silymarin; Taiwan	1997
Differential biochemical response of freshly isolated rat hepatocytes to paracetamol, carbon tetrachloride and D-galactosamine toxicity. Indian journal of experimental biology, 1997, Volume: 35, Issue:6 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Carbon Tetrachloride Poisoning; Cell Separation; Galactosamine; Guinea Pigs; Liver; Male; Rats	1997
Silymarin mediated differential modulation of toxicity induced by carbon tetrachloride, paracetamol and D-galactosamine in freshly isolated rat hepatocytes. Indian journal of experimental biology, 1997, Volume: 35, Issue:6 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Carbon Tetrachloride Poisoning; Drug Evaluation, Preclinical; Galactosamine; Guinea Pigs; Liver; Male; Rats; Silymarin	1997
Antihepatotoxic activity of monomethyl fumarate isolated from Fumaria indica. Journal of ethnopharmacology, 1998, Volume: 60, Issue:3 Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Fumarates; Galactosamine; Liver; Male; Maleates; Plant Extracts; Rats; Rats, Wistar; Rifampin; Silymarin; Thioacetamide	1998
Antihepatotoxic activity of Swertia chirata on paracetamol and galactosamine induced hepatotoxicity in rats. Phytotherapy research : PTR, 1999, Volume: 13, Issue:2 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Galactosamine; Liver Diseases; Liver Function Tests; Male; Phytotherapy; Plant Extracts; Rats	1999
Ameliorative effect of an urinary preparation on acetaminophen and D-galactosamine induced hepatotoxicity in rats. The American journal of Chinese medicine, 1999, Volume: 27, Issue:1 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Galactosamine; Glutathione; Humans; Lipid Peroxidation; Liver; Liver Diseases; Male; Rats; Rats, Wistar; Urine	1999
Effect of a herbal protein CI-1, purified from Cajanus indicus on the ultrastructural study of hepatocytes, in models of liver failure in mice. Journal of ethnopharmacology, 2001, Volume: 77, Issue:1 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Carbon Tetrachloride; Central Nervous System Depressants; Ethanol; Fabaceae; Galactosamine; Liver; Liver Failure; Male; Mice; Phytotherapy; Plant Extracts; Plant Leaves; Plant Proteins; Plants, Medicinal	2001
Messenger RNA profiles in liver injury and stress: a comparison of lethal and nonlethal rat models. Biochemical and biophysical research communications, 2002, Jan-11, Volume: 290, Issue:1 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Area Under Curve; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Galactosamine; Hepatocytes; Irritants; Lipopolysaccharides; Liver; Male; Rats; Rats, Wistar; Regeneration; RNA, Messenger; Time Factors; Transcription, Genetic; Turpentine	2002
Animal models of fulminant hepatic failure: need to test liver support devices. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2001, Volume: 33, Issue:7 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Disease Models, Animal; Dogs; Galactosamine; Hepatectomy; Humans; Liver Failure; Liver Transplantation; Liver, Artificial; Swine	2001
Primary cultures of human hepatocytes as a tool in cytotoxicity studies: cell protection against model toxins by flavonolignans obtained from Silybum marianum. Toxicology letters, 2003, Feb-03, Volume: 137, Issue:3 Topics: Acetaminophen; Analgesics, Non-Narcotic; Antioxidants; Asteraceae; Biphenyl Compounds; Cell Separation; Cell Survival; Cells, Cultured; Flavonoids; Free Radical Scavengers; Galactosamine; Hepatocytes; Humans; L-Lactate Dehydrogenase; Lignans; Picrates; Plant Extracts; Propanols; Protein Biosynthesis; tert-Butylhydroperoxide; Toxins, Biological	2003
Glycosmis arborea extract as a hepatoprotective agent. Phytotherapy research : PTR, 2003, Volume: 17, Issue:5 Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Body Weight; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Galactosamine; Lethal Dose 50; Lipid Peroxidation; Liver; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Rutaceae; Superoxide Dismutase; Survival Rate; Toxicity Tests, Acute	2003
Characterisation of some cytotoxic endpoints using rat liver and HepG2 spheroids as in vitro models and their application in hepatotoxicity studies. I. Glucose metabolism and enzyme release as cytotoxic markers. Toxicology and applied pharmacology, 2003, Jun-01, Volume: 189, Issue:2 Topics: Acetaminophen; Animals; Cell Survival; Diclofenac; Galactosamine; gamma-Glutamyltransferase; Glucose; Hepatocytes; L-Lactate Dehydrogenase; Liver; Male; Models, Biological; Propranolol; Rats; Rats, Sprague-Dawley; Spheroids, Cellular; Toxicity Tests; Xenobiotics	2003
Characterisation of some cytotoxic endpoints using rat liver and HepG2 spheroids as in vitro models and their application in hepatotoxicity studies. II. Spheroid cell spreading inhibition as a new cytotoxic marker. Toxicology and applied pharmacology, 2003, Jun-01, Volume: 189, Issue:2 Topics: Acetaminophen; Animals; Cell Movement; Cell Survival; Culture Media; Diclofenac; Galactosamine; Hepatocytes; Liver; Male; Propranolol; Rats; Rats, Sprague-Dawley; Spheroids, Cellular; Toxicity Tests; Xenobiotics	2003
Small scale rat hepatocyte primary culture with applications for screening hepatoprotective substances. Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:8 Topics: Acetaminophen; Animals; Cell Culture Techniques; Cell Survival; Collagen; Dexamethasone; Drug Combinations; Drug Evaluation, Preclinical; Galactosamine; Glycyrrhiza; Hepatocytes; Insulin; Laminin; Liver; Male; Plant Extracts; Proteoglycans; Rats; Rats, Sprague-Dawley; Schisandra	2003
Chemistry and hepatoprotective activity of an active fraction from Barleria prionitis Linn. in experimental animals. Phytotherapy research : PTR, 2005, Volume: 19, Issue:5 Topics: Acanthaceae; Acetaminophen; Administration, Oral; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Galactosamine; Lethal Dose 50; Male; Mice; Phytotherapy; Plant Extracts; Plant Leaves; Plant Stems; Protective Agents; Rats	2005
Cytochrome c: a non-invasive biomarker of drug-induced liver injury. Journal of applied toxicology : JAT, 2008, Volume: 28, Issue:7 Topics: Acetaminophen; Acute Disease; Animals; Apoptosis; Biomarkers; Chemical and Drug Induced Liver Injury; Cytochromes c; Disease Models, Animal; Dose-Response Relationship, Drug; Galactosamine; Hepatocytes; Male; Mitochondria; Necrosis; Rats; Rats, Sprague-Dawley	2008
Intestinal glucose uptake protects liver from lipopolysaccharide and D-galactosamine, acetaminophen, and alpha-amanitin in mice. The American journal of pathology, 2009, Volume: 175, Issue:3 Topics: Acetaminophen; Administration, Oral; Alpha-Amanitin; Animals; Chemical and Drug Induced Liver Injury; Fructose; Galactosamine; Glucose; Interleukin-10; Intestinal Mucosa; Lipopolysaccharides; Liver Diseases; Mice; Mice, Inbred C57BL; Signal Transduction; Sodium-Glucose Transporter 1; Sucrose; Toll-Like Receptor 4	2009
Protection by dietary Spirulina platensis against D-galactosamine--and acetaminophen-induced liver injuries. The British journal of nutrition, 2010, Volume: 103, Issue:11 Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Diet; Galactosamine; Interleukin-18; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; RNA, Messenger; Spirulina; Thiobarbituric Acid Reactive Substances	2010
Quantitative analyses and transcriptomic profiling of circulating messenger RNAs as biomarkers of rat liver injury. Hepatology (Baltimore, Md.), 2010, Volume: 51, Issue:6 Topics: Acetaminophen; Alanine Transaminase; Albumins; Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Aspartate Aminotransferases; Biomarkers; Bupivacaine; Centrifugation, Density Gradient; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Fibrinogen; Galactosamine; Gene Expression Profiling; Haptoglobins; In Situ Hybridization; Liver; Male; Necrosis; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sensitivity and Specificity; Time Factors	2010
Hepatoprotective effects of flavonoids from shekwasha (Citrus depressa) against D-galactosamine-induced liver injury in rats. Journal of nutritional science and vitaminology, 2010, Volume: 56, Issue:1 Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Citrus; DNA Fragmentation; Flavones; Flavonoids; Galactosamine; Lipopolysaccharides; Liver; Male; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; RNA, Messenger; Tumor Necrosis Factor-alpha	2010
Influence of small doses of various drug vehicles on acetaminophen-induced liver injury. Canadian journal of physiology and pharmacology, 2010, Volume: 88, Issue:10 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers; Galactosamine; Lipopolysaccharides; Liver Function Tests; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver	2010
Mouse strain-dependent caspase activation during acetaminophen hepatotoxicity does not result in apoptosis or modulation of inflammation. Toxicology and applied pharmacology, 2011, Dec-15, Volume: 257, Issue:3 Topics: Acetaminophen; Animals; Apoptosis; Caspase 3; Chemical and Drug Induced Liver Injury; Endotoxins; Fasting; Galactosamine; Glutathione; Hepatocytes; Inflammation; Male; Mice; Mice, Inbred C57BL; Neutrophils; Species Specificity	2011
Reference genes for real-time PCR quantification of microRNAs and messenger RNAs in rat models of hepatotoxicity. PloS one, 2012, Volume: 7, Issue:5 Topics: Acetaminophen; Actins; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Galactosamine; Gene Expression; Gene Expression Profiling; Glyceraldehyde-3-Phosphate Dehydrogenases; Liver; MicroRNAs; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Nuclear; Thioacetamide	2012
Antihepatotoxic activity of a quantified Desmodium adscendens decoction and D-pinitol against chemically-induced liver damage in rats. Journal of ethnopharmacology, 2013, Mar-07, Volume: 146, Issue:1 Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Ethanol; Fabaceae; Galactosamine; Inositol; Male; Phytotherapy; Plant Extracts; Plant Leaves; Plant Stems; Protective Agents; Rats; Rats, Sprague-Dawley; Rats, Wistar	2013
Protection of a ceramide synthase 2 null mouse from drug-induced liver injury: role of gap junction dysfunction and connexin 32 mislocalization. The Journal of biological chemistry, 2013, Oct-25, Volume: 288, Issue:43 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Ceramides; Chemical and Drug Induced Liver Injury; Connexins; Galactosamine; Gap Junction beta-1 Protein; Gap Junctions; Glutathione; Hepatocytes; Membrane Microdomains; Mice; Mice, Mutant Strains; Sphingosine N-Acyltransferase	2013
Acute liver injury induces nucleocytoplasmic redistribution of hepatic methionine metabolism enzymes. Antioxidants & redox signaling, 2014, Jun-01, Volume: 20, Issue:16 Topics: Acetaminophen; Acute Disease; Adenosylhomocysteinase; Animals; Chemical and Drug Induced Liver Injury; Cytoplasm; Galactosamine; Liver; Male; Methionine; Methionine Adenosyltransferase; Rats; Rats, Wistar; Tumor Cells, Cultured	2014
Induction of Nrf2 and metallothionein as a common mechanism of hepatoprotective medicinal herbs. The American journal of Chinese medicine, 2014, Volume: 42, Issue:1 Topics: Acetaminophen; Animals; Antioxidants; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Galactosamine; Glutamate-Cysteine Ligase; Heme Oxygenase-1; Liver; Male; Metallothionein; Mice; Mice, Inbred Strains; Molecular Targeted Therapy; NAD(P)H Dehydrogenase (Quinone); NADP; NF-E2-Related Factor 2; Oxidative Stress; Phytotherapy; Piper; Plant Extracts	2014
Broccoli sprout extract induces detoxification-related gene expression and attenuates acute liver injury. World journal of gastroenterology, 2015, Sep-21, Volume: 21, Issue:35 Topics: Acetaminophen; Animals; Biomarkers; Brassica; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Galactosamine; Gene Expression Profiling; Gene Expression Regulation; Glutathione; Inactivation, Metabolic; Liver; Male; Oligonucleotide Array Sequence Analysis; Phytotherapy; Plant Extracts; Plants, Medicinal; Protective Agents; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Seedlings; Time Factors	2015
Development of an optimized cytotoxicity assay system for CYP3A4-mediated metabolic activation via modified piggyBac transposition. Toxicology in vitro : an international journal published in association with BIBRA, 2016, Volume: 32 Topics: Acetaminophen; Activation, Metabolic; Biological Assay; Cell Survival; Chromans; Citric Acid; Cytochrome P-450 CYP3A; DNA Transposable Elements; Galactosamine; Hep G2 Cells; Humans; Nerve Tissue Proteins; Thiazolidinediones; Troglitazone	2016
c-Jun N-terminal kinase mediates mouse liver injury through a novel Sab (SH3BP5)-dependent pathway leading to inactivation of intramitochondrial Src. Hepatology (Baltimore, Md.), 2016, Volume: 63, Issue:6 Topics: Acetaminophen; Adaptor Proteins, Signal Transducing; Adenoviridae; Animals; Chemical and Drug Induced Liver Injury; Galactosamine; JNK Mitogen-Activated Protein Kinases; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Liver; Mitochondrial Proteins; Protein Tyrosine Phosphatase, Non-Receptor Type 6; src-Family Kinases; Tumor Necrosis Factor-alpha	2016
The role of MAP2 kinases and p38 kinase in acute murine liver injury models. Cell death & disease, 2017, 06-29, Volume: 8, Issue:6 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Galactosamine; Gene Knockdown Techniques; Hepatocytes; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 7; MAP Kinase Signaling System; Membrane Proteins; Mice; Microtubule-Associated Proteins; Mitochondria, Liver; Mitochondrial Proteins; Oligonucleotides, Antisense; p38 Mitogen-Activated Protein Kinases	2017
Lactobacillus reuteri DSM 17938 alleviates d-galactosamine-induced liver failure in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 133 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cytokines; Disease Models, Animal; Dysbiosis; Galactosamine; Gastrointestinal Microbiome; Ileum; Inflammation Mediators; Limosilactobacillus reuteri; Liver; Liver Failure; Male; Metabolome; Peroxisome Proliferator-Activated Receptors; Probiotics; Rats, Sprague-Dawley; Signal Transduction; Transcriptome	2021
Preclinical validation of silibinin/albumin nanoparticles as an applicable system against acute liver injury. Acta biomaterialia, 2022, 07-01, Volume: 146 Topics: Acetaminophen; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Galactosamine; Lipopolysaccharides; Liver; Mice; Nanoparticles; Serum Albumin, Bovine; Silybin	2022