Page last updated: 2024-09-04

gadolinium dtpa and sorafenib

gadolinium dtpa has been researched along with sorafenib in 7 studies

Compound Research Comparison

Studies
(gadolinium dtpa)
Trials
(gadolinium dtpa)
Recent Studies (post-2010)
(gadolinium dtpa)
Studies
(sorafenib)
Trials
(sorafenib)
Recent Studies (post-2010) (sorafenib)
12,6546644,0516,5207305,251

Protein Interaction Comparison

ProteinTaxonomygadolinium dtpa (IC50)sorafenib (IC50)
Aurora kinase AHomo sapiens (human)3.8
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)3.6
Bile salt export pumpHomo sapiens (human)8.6667
Tyrosine-protein kinase ABL1Homo sapiens (human)0.1
Tyrosine-protein kinase ABL1Mus musculus (house mouse)0.2259
Epidermal growth factor receptorHomo sapiens (human)0.2145
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)0.1333
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.131
Platelet-derived growth factor receptor betaMus musculus (house mouse)0.1235
Insulin receptorHomo sapiens (human)5.3
Tyrosine-protein kinase LckHomo sapiens (human)0.06
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.0385
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)0.026
Hepatocyte growth factor receptorHomo sapiens (human)5.75
Tyrosine-protein kinase HCKHomo sapiens (human)0.53
Platelet-derived growth factor receptor betaHomo sapiens (human)0.1164
Serine/threonine-protein kinase A-RafHomo sapiens (human)0.0087
Mast/stem cell growth factor receptor KitHomo sapiens (human)0.1937
Fibroblast growth factor receptor 1Homo sapiens (human)0.2827
AromataseHomo sapiens (human)0.1269
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.39
Serine/threonine-protein kinase B-rafHomo sapiens (human)0.3699
Platelet-derived growth factor receptor alphaHomo sapiens (human)0.427
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.06
Cyclin-CHomo sapiens (human)0.0663
Mitogen-activated protein kinase 3 Homo sapiens (human)0.0181
Serine/threonine-protein kinase B-raf Mus musculus (house mouse)0.13
Mitogen-activated protein kinase 1Homo sapiens (human)0.1095
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.0011
Bifunctional epoxide hydrolase 2Homo sapiens (human)0.012
Vascular endothelial growth factor receptor 3Homo sapiens (human)0.0191
Vascular endothelial growth factor receptor 3Mus musculus (house mouse)0.1269
Vascular endothelial growth factor receptor 2Mus musculus (house mouse)0.1129
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.1
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.0348
Casein kinase I isoform alphaHomo sapiens (human)0.25
Cyclin-dependent kinase 8Homo sapiens (human)1.1294
Glycogen synthase kinase-3 betaHomo sapiens (human)5.77
Ephrin type-B receptor 4Homo sapiens (human)0.5442
Fatty-acid amide hydrolase 1Rattus norvegicus (Norway rat)6.1
Cyclin-dependent kinase 6Homo sapiens (human)0.13
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)3.3
Angiopoietin-1 receptorHomo sapiens (human)0.0032
Tyrosine-protein kinase MerHomo sapiens (human)1.37
Receptor-interacting serine/threonine-protein kinase 1Homo sapiens (human)1.5
Mitogen-activated protein kinase 14Homo sapiens (human)0.6228
Discoidin domain-containing receptor 2Homo sapiens (human)0.0215
Serine/threonine-protein kinase TNNI3KHomo sapiens (human)0.175
Vascular endothelial growth factor receptor 2Danio rerio (zebrafish)2.6
Homeodomain-interacting protein kinase 1Homo sapiens (human)0.1
Homeodomain-interacting protein kinase 4Homo sapiens (human)0.0515
Cyclin-dependent kinase 19Homo sapiens (human)0.206
Homeodomain-interacting protein kinase 2Homo sapiens (human)0.1
Homeodomain-interacting protein kinase 3Homo sapiens (human)0.1
MAP kinase-interacting serine/threonine-protein kinase 2Homo sapiens (human)0.262
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)3.1

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's5 (71.43)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Hahn, OM; Karczmar, G; Karrison, T; Kistner, E; Manchen, E; Medved, M; Mitchell, M; Ratain, MJ; Stadler, WM; Yang, C1
Kudo, M1
Akisik, MF; Bu, G; Chiorean, EG; Hutchins, GD; Lin, C; Sandrasegaran, K1
Bitzer, M; Claussen, CD; Fenchel, M; Gregor, M; Horger, M; Lauer, UM; Spira, D1
Arencibia, JM; Augusto, EA; Groner, B; Ibrahim, AA; Kakoschky, B; Köberle, V; Korf, HW; Korkusuz, H; Kronenberger, B; Piiper, A; Pleli, T; Schmithals, C; Vafaizadeh, V; Vogl, TJ; Waidmann, O; Zeuzem, S1
Cai, H; Dong, Y; Dong, Z; Feng, ST; Huang, K; Huang, M; Jia, Y; Li, ZP; Liao, B; Luo, Y; Xu, L; Zhou, X1
Bargellini, I; Berg, T; Gasbarrini, A; Iezzi, R; Klümpen, HJ; Malfertheiner, P; Öcal, O; Pech, M; Peynircioglu, B; Ricke, J; Rössler, D; Sangro, B; Schulz, C; Schütte, K; Seidensticker, M; van Delden, O1

Trials

3 trial(s) available for gadolinium dtpa and sorafenib

ArticleYear
Dynamic contrast-enhanced magnetic resonance imaging pharmacodynamic biomarker study of sorafenib in metastatic renal carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Oct-01, Volume: 26, Issue:28

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Area Under Curve; Benzenesulfonates; Biomarkers, Tumor; Carcinoma, Renal Cell; Contrast Media; Double-Blind Method; Female; Gadolinium DTPA; Humans; Kidney Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Placebos; Proportional Hazards Models; Prospective Studies; Pyridines; Sorafenib; Survival Analysis; Treatment Outcome

2008
Pancreatic cancer: utility of dynamic contrast-enhanced MR imaging in assessment of antiangiogenic therapy.
    Radiology, 2010, Volume: 256, Issue:2

    Topics: Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Benzenesulfonates; Contrast Media; Female; Gadolinium DTPA; Humans; Image Enhancement; Magnetic Resonance Imaging; Male; Middle Aged; Niacinamide; Pancreatic Neoplasms; Phenylurea Compounds; Prognosis; Pyridines; Reproducibility of Results; Sensitivity and Specificity; Sorafenib; Treatment Outcome

2010
Gadoxetic acid uptake as a molecular imaging biomarker for sorafenib resistance in patients with hepatocellular carcinoma: a post hoc analysis of the SORAMIC trial.
    Journal of cancer research and clinical oncology, 2022, Volume: 148, Issue:9

    Topics: Biomarkers; Carcinoma, Hepatocellular; Catenins; Contrast Media; Gadolinium DTPA; Humans; Liver Neoplasms; Magnetic Resonance Imaging; Molecular Imaging; Retrospective Studies; Sorafenib

2022

Other Studies

4 other study(ies) available for gadolinium dtpa and sorafenib

ArticleYear
The 2008 Okuda lecture: Management of hepatocellular carcinoma: from surveillance to molecular targeted therapy.
    Journal of gastroenterology and hepatology, 2010, Volume: 25, Issue:3

    Topics: Algorithms; alpha-Fetoproteins; Antineoplastic Agents; Benzenesulfonates; Biomarkers; Biomarkers, Tumor; Carcinoma, Hepatocellular; Contrast Media; Early Detection of Cancer; Gadolinium DTPA; Humans; Infusion Pumps; Japan; Liver Neoplasms; Magnetic Resonance Imaging; Mass Screening; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Population Surveillance; Protein Precursors; Prothrombin; Pyridines; Sensitivity and Specificity; Sorafenib; Survival Rate

2010
Comparison of different tumor response criteria in patients with hepatocellular carcinoma after systemic therapy with the multikinase inhibitor sorafenib.
    Academic radiology, 2011, Volume: 18, Issue:1

    Topics: Adult; Aged; alpha-Fetoproteins; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Contrast Media; Female; Follow-Up Studies; Gadolinium DTPA; Humans; Image Enhancement; Liver; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Necrosis; Niacinamide; Phenylurea Compounds; Pyridines; Retrospective Studies; Sorafenib; Treatment Outcome; Tumor Burden

2011
Improving Drug Penetrability with iRGD Leverages the Therapeutic Response to Sorafenib and Doxorubicin in Hepatocellular Carcinoma.
    Cancer research, 2015, Aug-01, Volume: 75, Issue:15

    Topics: Administration, Intravenous; Amino Acid Motifs; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Doxorubicin; Drug Delivery Systems; Evans Blue; Gadolinium DTPA; Hep G2 Cells; Humans; Liver Neoplasms; Magnetic Resonance Imaging; Male; Mice, Nude; Mice, Transgenic; Niacinamide; Oligopeptides; Phenylurea Compounds; Sorafenib; Tissue Distribution

2015
Prediction of sorafenib treatment-related gene expression for hepatocellular carcinoma: preoperative MRI and histopathological correlation.
    European radiology, 2019, Volume: 29, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Contrast Media; Feasibility Studies; Female; Gadolinium DTPA; Humans; Image Enhancement; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Preoperative Period; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-raf; Retrospective Studies; Risk Factors; Sorafenib; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factor Receptor-3

2019