gacyclidine has been researched along with n-methylaspartate in 7 studies
| Studies (gacyclidine) | Trials (gacyclidine) | Recent Studies (post-2010) (gacyclidine) | Studies (n-methylaspartate) | Trials (n-methylaspartate) | Recent Studies (post-2010) (n-methylaspartate) |
|---|---|---|---|---|---|
| 36 | 1 | 2 | 10,408 | 59 | 1,902 |
| Protein | Taxonomy | gacyclidine (IC50) | n-methylaspartate (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 5.175 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 5.175 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Drian, MJ; Kamenka, JM; Pirat, JL; Privat, A | 1 |
| Calvet, MC; Kamenka, JM; Levallois, C; Petite, D | 1 |
| Baubichon, D; Carpentier, P; Clarençon, D; Galonnier, M; Lallement, G; Peoc'h, M | 1 |
| d'Arbigny, P; Dukic, S; Hoizey, G; Lamiable, D; Millart, H; Vistelle, R | 1 |
| Barbanel, G; Kamenka, JM; Laplanche, L | 1 |
| d'Arbigny, P; Gaviria, M; Haton, H; Kamenka, J; Ohanna, F; Privat, A | 1 |
| Bauchet, L; Gaviria, M; Haton, H; Kouyoumdjian, P; Lonjon, N; Perrin, FE; Prieto, M; Privat, A | 1 |
1 review(s) available for gacyclidine and n-methylaspartate
| Article | Year |
|---|---|
Review of the value of gacyclidine (GK-11) as adjuvant medication to conventional treatments of organophosphate poisoning: primate experiments mimicking various scenarios of military or terrorist attack by soman.
Topics: Animals; Cyclohexanes; Cyclohexenes; Excitatory Amino Acid Antagonists; Haplorhini; Humans; N-Methylaspartate; Organophosphorus Compounds; Piperidines; Receptors, N-Methyl-D-Aspartate; Seizures; Soman; Time Factors | 1999 |
6 other study(ies) available for gacyclidine and n-methylaspartate
| Article | Year |
|---|---|
Non-competitive antagonists of N-methyl-D-aspartate prevent spontaneous neuronal death in primary cultures of embryonic rat cortex.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclohexanes; Cyclohexenes; Dizocilpine Maleate; Embryo, Mammalian; Female; N-Methylaspartate; Neurons; Phencyclidine; Piperidines; Pregnancy; Rats; Rats, Inbred Strains | 1991 |
Neuroprotective effect of N-methyl-D-aspartate non-competitive antagonists (arylcyclohexylamine derivatives) on human cultured spinal cord cells.
Topics: Cells, Cultured; Cyclohexanes; Cyclohexenes; Cyclohexylamines; gamma-Aminobutyric Acid; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; N-Methylaspartate; Neurites; Neuroglia; Neurons; Piperidines; Spinal Cord; Stereoisomerism | 1994 |
Sensitive gas chromatographic-mass spectrometric method for the determination of gacyclidine in rat plasma and spinal cord dialyzates.
Topics: Animals; Cyclohexanes; Cyclohexenes; Gas Chromatography-Mass Spectrometry; Male; Microdialysis; N-Methylaspartate; Piperidines; Rats; Rats, Wistar; Sensitivity and Specificity | 1999 |
The novel non-competitive N-methyl-D-aspartate antagonist gacyclidine blocks the glutamate-induced release of hydroxyl radicals in the striatum under conditions in which dizocilpine does not. A microdialysis study in rats.
Topics: Animals; Binding, Competitive; Corpus Striatum; Cyclohexanes; Cyclohexenes; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Hydroxyl Radical; Male; Microdialysis; N-Methylaspartate; Neuroprotective Agents; Oxidative Stress; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2000 |
Neuroprotective effects of a novel NMDA antagonist, Gacyclidine, after experimental contusive spinal cord injury in adult rats.
Topics: Animals; Contusions; Cyclohexanes; Cyclohexenes; Electrophysiology; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Male; Motor Activity; N-Methylaspartate; Neuroprotective Agents; Piperidines; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Time Factors; Weight Gain | 2000 |
Early functional outcomes and histological analysis after spinal cord compression injury in rats.
Topics: Animals; Autonomic Nervous System; Catheterization; Cyclohexenes; Disease Models, Animal; Excitatory Amino Acid Antagonists; Male; Motor Activity; N-Methylaspartate; Piperidines; Rats; Rats, Wistar; Reflex; Sensory Receptor Cells; Spinal Cord; Spinal Cord Compression; Spinal Cord Injuries; Urination | 2010 |