Page last updated: 2024-09-05

gacyclidine and dizocilpine maleate

gacyclidine has been researched along with dizocilpine maleate in 6 studies

Compound Research Comparison

Studies
(gacyclidine)
Trials
(gacyclidine)
Recent Studies (post-2010)
(gacyclidine)
Studies
(dizocilpine maleate)
Trials
(dizocilpine maleate)
Recent Studies (post-2010) (dizocilpine maleate)
36127,74191,449

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Drian, MJ; Kamenka, JM; Pirat, JL; Privat, A1
Barbanel, G; Kamenka, JM; Laplanche, L1
Arnaud, S; D'Arbigny, P; Feldblum, S; Rabin, O; Simon, M1
Hirbec, H; Kamenka, JM; Privat, A; Vignon, J1
Becerril Ortega, J; Buisson, A; Crouzin, N; Desmadryl, G; Hirbec, H; Privat, A; Teigell, M; Vandame, D1
Hirbec, H; Nesic, O; Perez-Polo, R; Prieto-Cappellini, M; Privat, A; Teigell, M; Ulmann, L; Vandame, D; Vignon, J1

Other Studies

6 other study(ies) available for gacyclidine and dizocilpine maleate

ArticleYear
Non-competitive antagonists of N-methyl-D-aspartate prevent spontaneous neuronal death in primary cultures of embryonic rat cortex.
    Journal of neuroscience research, 1991, Volume: 29, Issue:1

    Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclohexanes; Cyclohexenes; Dizocilpine Maleate; Embryo, Mammalian; Female; N-Methylaspartate; Neurons; Phencyclidine; Piperidines; Pregnancy; Rats; Rats, Inbred Strains

1991
The novel non-competitive N-methyl-D-aspartate antagonist gacyclidine blocks the glutamate-induced release of hydroxyl radicals in the striatum under conditions in which dizocilpine does not. A microdialysis study in rats.
    Neuroscience letters, 2000, Jul-28, Volume: 289, Issue:1

    Topics: Animals; Binding, Competitive; Corpus Striatum; Cyclohexanes; Cyclohexenes; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Hydroxyl Radical; Male; Microdialysis; N-Methylaspartate; Neuroprotective Agents; Oxidative Stress; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

2000
Efficacy of a new neuroprotective agent, gacyclidine, in a model of rat spinal cord injury.
    Journal of neurotrauma, 2000, Volume: 17, Issue:11

    Topics: Animals; Astrocytes; Cyclohexanes; Cyclohexenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Female; Gliosis; Guanidines; Neuroprotective Agents; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Stereoisomerism

2000
Interaction of gacyclidine enantiomers with 'non-NMDA' binding sites in the rat central nervous system.
    Brain research, 2001, Mar-16, Volume: 894, Issue:2

    Topics: Animals; Autoradiography; Binding Sites; Brain Chemistry; Cerebellum; Cyclohexanes; Cyclohexenes; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Tritium

2001
Comparison of the pharmacological properties of GK11 and MK801, two NMDA receptor antagonists: towards an explanation for the lack of intrinsic neurotoxicity of GK11.
    Journal of neurochemistry, 2007, Volume: 103, Issue:4

    Topics: Animals; Cells, Cultured; Cyclohexenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hippocampus; Mice; Neuroprotective Agents; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate

2007
Development of NMDAR antagonists with reduced neurotoxic side effects: a study on GK11.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Animals; Astrocytes; Cyclohexenes; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Gyrus Cinguli; Inflammation; Injections, Intraperitoneal; Memantine; Microglia; Neurons; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2013