Page last updated: 2024-09-05

gacyclidine and atropine

gacyclidine has been researched along with atropine in 3 studies

Compound Research Comparison

Studies
(gacyclidine)
Trials
(gacyclidine)
Recent Studies (post-2010)
(gacyclidine)
Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010) (atropine)
361226,7111,2591,697

Protein Interaction Comparison

ProteinTaxonomygacyclidine (IC50)atropine (IC50)
cystic fibrosis transmembrane conductance regulatorHomo sapiens (human)21.41
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.012
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.0067
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.0007
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.0009
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.0015
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.0021
Alpha-1D adrenergic receptorHomo sapiens (human)1.354
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.012

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baubichon, D; Burckhart, MF; Clarençon, D; Galonnier, M; Lallement, G; Masqueliez, C; Mestries, JC; Peoc'h, M1
Baubichon, D; Burckhart, MF; Clarençon, D; Galonnier, M; Lallement, G; Peoc'h, M1
Lallement, G1

Other Studies

3 other study(ies) available for gacyclidine and atropine

ArticleYear
Nerve agent poisoning in primates: antilethal, anti-epileptic and neuroprotective effects of GK-11.
    Archives of toxicology, 1998, Volume: 72, Issue:2

    Topics: Animals; Anticonvulsants; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cyclohexanes; Cyclohexenes; Diazepam; Drug Combinations; Excitatory Amino Acid Antagonists; Injections, Intravenous; Macaca fascicularis; Male; Muscarinic Antagonists; Neuroprotective Agents; Piperidines; Pralidoxime Compounds; Seizures; Soman; Staining and Labeling; Time Factors

1998
Acute soman poisoning in primates neither pretreated nor receiving immediate therapy: value of gacyclidine (GK-11) in delayed medical support.
    Archives of toxicology, 1999, Volume: 73, Issue:2

    Topics: Animals; Anticonvulsants; Antidotes; Atropine; Brain; Cerebellum; Cerebral Cortex; Chemical Warfare Agents; Cholinesterase Reactivators; Cyclohexanes; Cyclohexenes; Diazepam; Drug Therapy, Combination; Electrocardiography; Excitatory Amino Acid Antagonists; Haplorhini; Macaca fascicularis; Male; Piperidines; Poisoning; Pralidoxime Compounds; Seizures; Soman; Time Factors

1999
[Interest in an glutamate antagonistic compound for the treatment of organophosphate poisoning].
    Annales pharmaceutiques francaises, 2000, Volume: 58, Issue:1

    Topics: Atropine; Cholinesterase Reactivators; Cyclohexanes; Cyclohexenes; Electroencephalography; Excitatory Amino Acid Antagonists; Humans; Organophosphate Poisoning; Piperidines; Poisoning; Pyridostigmine Bromide; Self Administration

2000