gabexate has been researched along with cholecystokinin in 75 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (34.67) | 18.7374 |
| 1990's | 35 (46.67) | 18.2507 |
| 2000's | 9 (12.00) | 29.6817 |
| 2010's | 5 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilski, J; Konturek, PK; Konturek, SJ; Krzyzek, E | 1 |
| Harada, E; Syuto, B | 1 |
| Chey, WY; Takeuchi, T; Watanabe, S | 1 |
| Jansen, JB; Lamers, CB; Meijers, M; Rovati, LC; van Garderen-Hoetmer, A; Woutersen, RA | 1 |
| Adler, G; Arnold, R; Koop, I; Lindenthal, M; Schade, M; Trautmann, M | 1 |
| Kanno, T; Terasawa, K | 1 |
| Adler, G; Elsässer, HP; Kern, HF; Puplat, D | 1 |
| Ferrell, LD; Grendell, JH; Lüthen, R; Niederau, C; Niederau, M; Strohmeyer, G | 1 |
| Alves, F; Creutzfeldt, W; Fölsch, UR; Löser, C; Stöckmann, F | 1 |
| Douglas, BR; Jansen, JB; Lamers, CB; Rovati, LC; Woutersen, RA | 1 |
| Cherian, L; Goebell, H; Jansen, JB; Lamers, CB; Layer, P | 1 |
| Ferrell, LD; Grendell, JH; Liddle, RA; Niederau, C | 1 |
| Adler, G; Kern, HF; Koop, I; Rausch, U; Rudolff, D; Weidenbach, F; Weidenbach, H | 1 |
| Grendell, JH; Liddle, RA; Niederau, C; Williams, JA | 1 |
| Adler, G; Göke, B; Göke, R; Leferink, J | 1 |
| Adler, G; Göke, B; Koop, I; Printz, H; Schafmayer, A; Weidenbach, H | 1 |
| Bamba, T; Hosoda, S; Nakagawa, M; Oishi, T | 1 |
| Cleffmann, U; Creutzfeldt, W; Fölsch, UR; Löser, C; Nustede, R | 1 |
| Choudhury, AR; Creutzfeldt, W; Fölsch, UR; Nustede, R; Schmidt, WE; Siegel, EG; Stöckmann, F; Wilms, HM | 1 |
| Dembinski, A; Jaworek, J; Konturek, PK; Konturek, SJ; Warzecha, Z | 1 |
| Adler, G; Arnold, R; Göke, B; Koop, I; Reinshagen, M; Rovati, LC; Schafmayer, A | 1 |
| de Jong, AJ; Douglas, BR; Jansen, JB; Lamers, CB; Rovati, LC; Woutersen, RA | 1 |
| Kitani, K; Miyasaka, K; Nakamura, R | 1 |
| Dimaline, R; Dockray, GJ; Green, T; Peikin, S | 1 |
| Göke, B; Keim, V | 1 |
| Adler, G; Arnold, R; Beglinger, C; Bozkurt, T; Göke, B; Koop, I; Müllenhoff, A | 1 |
| Adler, G; Arnold, R; Fenchel, K; Göke, B; Knobloch, S | 1 |
| Ammon, HP; Verspohl, EJ; Wunderle, G | 1 |
| McLaughlin, RE; Ozawa, S; Renner, IG; Rich, KA; Wisner, JR | 1 |
| Adler, G; Arnold, R; Bozkurt, T; Göke, B; Koop, I; Müllenhoff, A | 1 |
| Adler, G; Arnold, R; Göke, B; Koop, I; Printz, H; Rausch, U; Richter, G | 1 |
| Himeno, S; Kanayama, S; Kitani, T; Shinomura, Y; Tarui, S; Yamasaki, Y | 1 |
| Harada, E; Kato, S; Nakagawa, K | 1 |
| Creutzfeldt, W; Göke, B; Lankisch, PG; Otto, J; Stöckmann, F | 1 |
| Yonezawa, H | 2 |
| Goebell, H; Müller, MK; Rünzi, M; von Schönfeld, J | 1 |
| Creutzfeldt, W; Leonhardt, U; Seidensticker, F; Stöckmann, F | 1 |
| Fujii, M; Koide, M; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S | 1 |
| Fölsch, UR; Jäger, M; Köhler, H; Nustede, R; Peiper, HJ; Schmidt, WE; Stöckmann, F | 1 |
| Hopman, WP; Jansen, JB; Lamers, CB; Rosenbusch, G; Sloots, CE; Tangerman, A; Thimister, PW; Willems, HL | 1 |
| Büchler, M; Friess, H; Hajnal, F; Kisfalvi, K; Papp, M; Varga, G | 1 |
| Chang, CH; Chang, TM; Chey, WY; Leiter, A; Sun, Q | 1 |
| Köhler, H; Lüdtke, FE; Nustede, R; Streich, R | 1 |
| Fukumoto, M; Hayashi, H; Imamura, M; Kawabata, K; Manabe, T; Masai, Y; Morimoto, H; Nio, Y; Tsubono, M | 1 |
| Ishizuka, J; Parekh, D; Rajaraman, S; Thompson, JC; Townsend, CM | 1 |
| Köhler, H; Nustede, R; Schafmayer, A | 1 |
| Fujii, M; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S | 1 |
| Hopman, WP; Jansen, JB; Rosenbusch, G; Sloots, CE; Thimister, PW; Trijbels, FJ; Willems, HL | 1 |
| Agricola, B; Kern, HF; Kruse, ML; Schmidt, WE; Waschulewski, IH | 1 |
| Atomi, Y; Kobori, O; Kuroda, A; Muto, T; Sugiyama, M; Wada, N | 1 |
| Meisse, F; Müller, MK; von Schönfeld, J | 1 |
| Green, GM; Guan, D; Phillips, WT; Schwartz, JG | 1 |
| Atomi, Y; Kuroda, A; Muto, T; Sugiyama, M; Wada, N | 1 |
| Arai, I; Hirai, Y; Ida, Y; Komatsu, Y; Kuroiwa, Y; Sasaki, K; Shingu, K; Taguchi, S; Yamamoto, T; Yamaura, H | 1 |
| Otsuki, M; Shirohara, H; Yamamoto, M | 1 |
| D'Amato, M; Kisfalvi, K; Pelosini, I; Scarpignato, C; Varga, G | 1 |
| Büchler, MW; Friess, H; Isenmann, R; Kleeff, J; Malfertheiner, P | 1 |
| Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Kwiecień, S; Pajdo, R | 1 |
| Funakoshi, A; Kanai, S; Kawanami, T; Miyasaka, K; Shimazoe, T; Suzuki, S; Takata, Y; Watanabe, S; Yoshida, Y | 1 |
| Bragado, MJ; Tashiro, M; Williams, JA | 1 |
| Fink, H; Voigt, JP; Voits, M; Wenz, D | 1 |
| Chew, P; Eysselein, VE; Green, GM; Keire, DA; Reeve, JR | 1 |
| Liddle, RA; Samuelson, LC; Tashiro, M; Williams, JA | 1 |
| Green, GM; Keire, DA; Reeve, JR; Yamamoto, M | 1 |
| Ernst, SA; Guo, L; Gurda, GT; Lee, SH; Sans, MD; Williams, JA | 1 |
| Guo, L; Gurda, GT; Lee, SH; Molkentin, JD; Williams, JA | 1 |
| Crozier, SJ; D'Alecy, LG; Ernst, SA; Lang, CH; Sans, MD; Williams, JA | 1 |
| Cooper, MS; Green, GM; Raboin, SJ; Reeve, JR; Sayegh, AI | 1 |
| Crozier, SJ; Ernst, SA; Gurda, GT; Ji, B; Logsdon, CD; Rothermel, BA; Williams, JA | 1 |
| Lateef, DM; Sayegh, AI; Washington, MC | 1 |
| Lateef, DM; Mansour, MM; Raboin, SJ; Roberson, AE; Sayegh, AI; Washington, MC; Williams, CS | 1 |
| Jia, D; Otsuki, M; Yamamoto, M | 1 |
| Sayegh, AI; Washington, MC; Williams, K | 1 |
2 trial(s) available for gabexate and cholecystokinin
| Article | Year |
|---|---|
Comparison of the effect of single and repeated administrations of a protease inhibitor (Camostate) on pancreatic secretion in man.
Topics: Cholecystokinin; Esters; Food; Gabexate; Guanidines; Humans; Pancreas; Protease Inhibitors; Time Factors | 1988 |
Role of intraduodenal proteases in plasma cholecystokinin and pancreaticobiliary responses to protein and amino acids.
Topics: Adult; Albumins; Amino Acids; Amylases; Bilirubin; Cholecystokinin; Chymotrypsin; Duodenum; Endopeptidases; Esters; Female; Gabexate; Gallbladder; Gallbladder Emptying; Guanidines; Humans; Male; Pancreas; Pancreatic Polypeptide; Protease Inhibitors; Trypsin | 1996 |
73 other study(ies) available for gabexate and cholecystokinin
| Article | Year |
|---|---|
Feedback control of pancreatic secretion in rats. Role of gastric acid secretion.
Topics: Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Esters; Feedback; Gabexate; Gastric Acid; Gastric Fistula; Guanidines; Male; Omeprazole; Pancreas; Pancreatic Fistula; Protease Inhibitors; Rats; Rats, Wistar | 1992 |
Precocious alteration of digestive enzyme activities in small intestine and pancreas by chronic oral administration of protease inhibitor in suckling rats.
Topics: Administration, Oral; Adrenalectomy; Animals; Animals, Newborn; Benzodiazepinones; Cholecystokinin; Devazepide; Digestion; Esters; Gabexate; Guanidines; Injections, Subcutaneous; Intestine, Small; Pancreas; Protease Inhibitors; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin | 1991 |
Mediation of trypsin inhibitor-induced pancreatic hypersecretion by secretin and cholecystokinin in rats.
Topics: Analysis of Variance; Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Dose-Response Relationship, Drug; Esters; Gabexate; Guanidines; Immune Sera; Least-Squares Analysis; Male; Pancreas; Rabbits; Rats; Rats, Inbred Strains; Secretin; Trypsin Inhibitors | 1992 |
Effects of the synthetic trypsin inhibitor camostate on the development of N-nitrosobis(2-oxopropyl)amine-induced pancreatic lesions in hamsters.
Topics: Animals; Carcinogens; Carcinoma; Carcinoma in Situ; Cholecystokinin; Cricetinae; Esters; Gabexate; Guanidines; Male; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Proglumide; Reference Values; Trypsin Inhibitors | 1991 |
Role of cholecystokinin in cholestyramine-induced changes of the exocrine pancreas.
Topics: Administration, Oral; Animals; Benzodiazepinones; Cholecystokinin; Cholestyramine Resin; Chymotrypsin; Devazepide; Dimethyl Sulfoxide; DNA; Dose-Response Relationship, Drug; Esters; Gabexate; Guanidines; Hypertrophy; Male; Organ Size; Pancreas; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Time Factors; Trypsin; Trypsin Inhibitors | 1991 |
Elevation of resting fluid secretion precedes trophic responses in the rat pancreas following a single oral administration of Camostat.
Topics: Administration, Oral; Animals; Biological Transport; Cholecystokinin; Electrolytes; Esters; Gabexate; Guanidines; Hypertrophy; Male; Pancreas; Pancreatic Juice; Protease Inhibitors; Rats; Rats, Inbred Strains | 1991 |
Stimulation of pancreatic secretory process in the rat by low-molecular weight proteinase inhibitor. III. Changes in DNA synthesis and mitotic activity.
Topics: Animals; Cholecystokinin; DNA Replication; Esters; Gabexate; Guanidines; Male; Mitosis; Pancreas; Protease Inhibitors; Rats; Rats, Inbred Strains | 1990 |
Effects of long-term CCK stimulation and CCK blockade on pancreatic and intestinal growth, morphology, and function.
Topics: Animals; Cholecystokinin; Diet; Duodenum; Esters; Gabexate; Guanidines; Intestinal Mucosa; Mice; Mice, Inbred Strains; Pancreas; Proglumide; Protease Inhibitors; Time Factors | 1990 |
Acute and chronic effects of cyclosporine A on pancreatic polyamine metabolism and pancreatic adaptation.
Topics: Acetyltransferases; Adaptation, Physiological; Adenosylmethionine Decarboxylase; Animals; Biogenic Polyamines; Cholecystokinin; Cyclosporins; Esters; Gabexate; Guanidines; Male; Ornithine Decarboxylase; Pancreas; Rats; Rats, Inbred Strains; Trypsin Inhibitors | 1990 |
Comparison of the effect of lorglumide on pancreatic growth stimulated by camostate in rat and hamster.
Topics: Animals; Cholecystokinin; Cricetinae; DNA; Esters; Gabexate; Gelatin; Glutamine; Guanidines; Male; Mesocricetus; Organ Size; Pancreas; Proglumide; Proteins; Rats; Rats, Inbred Strains; Stimulation, Chemical; Trypsin Inhibitors | 1990 |
Feedback regulation of human pancreatic secretion. Effects of protease inhibition on duodenal delivery and small intestinal transit of pancreatic enzymes.
Topics: Adult; Ceruletide; Cholecystokinin; Dose-Response Relationship, Drug; Duodenum; Esters; Feedback; Gabexate; Gastrointestinal Transit; Guanidines; Humans; In Vitro Techniques; Intestinal Secretions; Intestine, Small; Intubation, Gastrointestinal; Pancreas; Protease Inhibitors; Reference Values; Secretin; Time Factors | 1990 |
Beneficial effects of cholecystokinin-receptor blockade and inhibition of proteolytic enzyme activity in experimental acute hemorrhagic pancreatitis in mice. Evidence for cholecystokinin as a major factor in the development of acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Cholecystokinin; Choline Deficiency; Disease Models, Animal; Ethionine; Female; Gabexate; Guanidines; Hemorrhage; Mice; Pancreas; Pancreatitis; Proglumide; Receptors, Cholecystokinin; Secretin; Time Factors; Trypsin | 1986 |
Stimulation of pancreatic secretory process in the rat by low-molecular weight proteinase inhibitor. I. Dose-response study on enzyme content and secretion, cholecystokinin release and pancreatic fine structure.
Topics: Amylases; Animals; Cholecystokinin; Chymotrypsin; Esters; Gabexate; Golgi Apparatus; Guanidines; Kinetics; Lipase; Male; Microscopy, Electron; Pancreas; Protease Inhibitors; Rats; Rats, Inbred Strains; Trypsin | 1987 |
[The Pancreas Study Group: Inhibition of pancreas secretion and trypsin activity. Mechanisms and importance of therapy of acute and chronic pancreatitis].
Topics: Adult; Animals; Aprotinin; Bicarbonates; Cholecystokinin; Chronic Disease; Dogs; Female; Gabexate; Guanidines; Humans; Injections, Subcutaneous; Lipase; Male; Octreotide; Pancreas; Pancreatitis; Receptors, Cholecystokinin; Secretin; Somatostatin; Trypsin | 1987 |
Pancreatic growth: interaction of exogenous cholecystokinin, a protease inhibitor, and a cholecystokinin receptor antagonist in mice.
Topics: Amylases; Animals; Cholecystokinin; Chymotrypsinogen; Esters; Gabexate; Glutamine; Guanidines; Male; Mice; Organ Size; Pancreas; Proglumide; Protease Inhibitors; Sincalide | 1987 |
Effect of a low-molecular weight serine proteinase inhibitor (camostate) on amylase release from isolated pancreatic acini.
Topics: Amylases; Animals; Ceruletide; Cholecystokinin; Esters; Gabexate; Guanidines; In Vitro Techniques; Male; Pancreas; Rats | 1989 |
Effect of atropine on feedback regulation of pancreatic secretion in rats.
Topics: Amylases; Animals; Atropine; Cholecystokinin; Chymotrypsin; Esters; Feedback; Gabexate; Guanidines; Lipase; Male; Pancreas; Pancreatic Juice; Protease Inhibitors; Rats; Rats, Inbred Strains; Time Factors; Trypsin | 1989 |
[Study on the trophic effect of camostate mesilate on ethionine-induced pancreatic injury rat].
Topics: Administration, Oral; Amylases; Animals; Cholecystokinin; Esters; Ethionine; Gabexate; Guanidines; In Vitro Techniques; Male; Pancreas; Pancreatic Diseases; Rats; Secretin; Trypsin Inhibitors | 1989 |
Role of ornithine decarboxylase and polyamines in camostate (Foy-305)-induced pancreatic growth in rats.
Topics: Animals; Cholecystokinin; Eflornithine; Esters; Gabexate; Guanidines; Kinetics; Male; Ornithine Decarboxylase; Pancreas; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine | 1989 |
Influence of CCK antagonist L-364,718, pancreastatin (33-49) and a somatostatin analogue on camostate-induced rat pancreatic hypertrophy.
Topics: Animals; Benzodiazepinones; Cholecystokinin; Chromogranin A; Devazepide; Esters; Gabexate; Guanidines; Hypertrophy; Male; Octreotide; Pancreas; Pancreatic Hormones; Protease Inhibitors; Rats; Rats, Inbred Strains | 1989 |
Cholecystokinin receptor antagonism by peptidergic and non-peptidergic agents in rat pancreas.
Topics: Animals; Benzodiazepinones; Bombesin; Ceruletide; Cholecystokinin; Devazepide; DNA; Esters; Gabexate; Glutamine; Guanidines; Pancreas; Pentagastrin; Proglumide; Protease Inhibitors; Proteins; Rats; Receptors, Cholecystokinin | 1989 |
Differential effects of atropine and a cholecystokinin receptor antagonist on pancreatic secretion.
Topics: Adult; Atropine; Cholecystokinin; Dose-Response Relationship, Drug; Esters; Feedback; Gabexate; Glutamine; Guanidines; Humans; Male; Pancreas; Peptide Hydrolases; Proglumide; Protease Inhibitors; Pulse; Reference Values | 1989 |
Modulation by CR-1409 (lorglumide), a cholecystokinin receptor antagonist, of trypsin inhibitor-enhanced growth of azaserine-induced putative preneoplastic lesions in rat pancreas.
Topics: Animals; Azaserine; Cholecystokinin; Esters; Gabexate; Glutamine; Guanidines; Male; Pancreatic Neoplasms; Precancerous Conditions; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Sincalide; Trypsin Inhibitors | 1989 |
Effects of trypsin inhibitor (camostate) on pancreas and CCK release in young and old female rats.
Topics: Aging; Animals; Body Weight; Cholecystokinin; Dose-Response Relationship, Drug; Esters; Female; Gabexate; Guanidines; Intubation, Gastrointestinal; Lipase; Organ Size; Pancreas; Protease Inhibitors; Rats; Rats, Inbred F344; Secretory Rate; Trypsin | 1989 |
Action of the cholecystokinin antagonist L364,718 on gastric emptying in the rat.
Topics: Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Esters; Gabexate; Gastric Emptying; Guanidines; Male; Peptide Hydrolases; Peptones; Rats; Rats, Inbred Strains; Sincalide | 1988 |
Pancreatic secretion in the rat influenced by the low molecular weight serine proteinase inhibitor Gabexate mesilate.
Topics: Animals; Cholecystokinin; Enzymes; Female; Gabexate; Guanidines; Infusions, Intravenous; Instillation, Drug; Pancreas; Protease Inhibitors; Proteins; Rats; Stomach | 1986 |
Stimulation of pancreatic secretion in man by a protease inhibitor (camostate).
Topics: Cholecystokinin; Dietary Carbohydrates; Dietary Proteins; Esters; Feedback; Gabexate; Guanidines; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Pancreas; Protease Inhibitors; Radioimmunoassay; Secretin; Trypsin | 1988 |
Increased CCK-response to proteinase inhibitor feeding after induction of pancreatic hypertrophy in rats.
Topics: Animals; Cholecystokinin; Dose-Response Relationship, Drug; Esters; Female; Gabexate; Guanidines; Hypertrophy; Pancreas; Protease Inhibitors; Rats; Rats, Inbred Strains | 1988 |
Proglumide antagonizes cholecystokinin effects on plasma glucose and insulin in rats in vivo.
Topics: Animals; Blood Glucose; Cholecystokinin; Esters; Female; Gabexate; Glucose Tolerance Test; Glutamine; Guanidines; Insulin Antagonists; Male; Proglumide; Protease Inhibitors; Rats; Rats, Inbred Strains | 1988 |
Effects of L-364,718, a new cholecystokinin receptor antagonist, on camostate-induced growth of the rat pancreas.
Topics: Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Esters; Gabexate; Guanidines; Hypertrophy; Male; Organ Size; Pancreas; Protease Inhibitors; Rats; Rats, Inbred Strains | 1988 |
Endogenous CCK release and pancreatic growth in rats after feeding a proteinase inhibitor (camostate).
Topics: Animals; Cholecystokinin; Esters; Female; Gabexate; Guanidines; Pancreas; Pancreatic Juice; Proglumide; Protease Inhibitors; Rats; Rats, Inbred Strains; Stimulation, Chemical; Time Factors | 1986 |
Effect of synthetic trypsin inhibitor on plasma immunoreactive cholecystokinin in rats.
Topics: Animals; Cerebral Cortex; Cholecystokinin; Duodenum; Esters; Gabexate; Guanidines; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Secretin; Trypsin Inhibitors | 1987 |
Characteristic secretory response of the exocrine pancreas in various mammalian and avian species.
Topics: Amylases; Animals; Chickens; Cholecystokinin; Chymotrypsin; Ducks; Electric Stimulation; Esters; Gabexate; Guanidines; Male; Mink; Pancreas; Pancreatic Juice; Rabbits; Rats; Rats, Inbred Strains; Sheep; Swine; Trypsin; Trypsin Inhibitors; Vagus Nerve | 1982 |
[Effect of FOY-305 on the activity and secretion of pancreatic enzymes in vitro].
Topics: Amylases; Animals; Cholecystokinin; Dose-Response Relationship, Drug; Esters; Gabexate; Guanidines; Humans; Male; Pancreas; Phospholipases; Phospholipases A; Phospholipases A2; Protease Inhibitors; Rats; Rats, Inbred Strains; Trypsin | 1984 |
Discrepancy between the potency of various trypsin inhibitors to inhibit trypsin activity and the potency to release biologically active cholecystokinin-pancreozymin.
Topics: Animals; Benzamidines; Cholecystokinin; Duodenum; Esters; Gabexate; Guanidines; Male; Pancreas; Rats; Rats, Inbred Strains; Stimulation, Chemical; Trypsin Inhibitors | 1984 |
Secretory responses of hypertrophied rat pancreas induced by repeated oral administrations of a synthetic protease inhibitor.
Topics: Acetylcholine; Administration, Oral; Animals; Cholecystokinin; Esters; Gabexate; Guanidines; Hypertrophy; In Vitro Techniques; Male; Pancreas; Protease Inhibitors; Rats; Rats, Inbred Strains | 1983 |
Endocrine and exocrine pancreatic function after camostate-induced growth of the organ.
Topics: Animals; Blood Glucose; Cholecystokinin; Esters; Gabexate; Glucagon; Guanidines; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Protease Inhibitors; Protein Biosynthesis; Rats; Rats, Wistar | 1995 |
Effect of camostate administration for two weeks on experimental pancreatitis in mice and rats.
Topics: Administration, Oral; Amylases; Animals; Cholecystokinin; Esters; Female; Gabexate; Guanidines; Male; Mice; Pancreas; Pancreatitis; Protease Inhibitors; Rats; Rats, Wistar | 1993 |
Differential effects of proteinase inhibitor camostat on exocrine pancreas in fed and fasted rats.
Topics: Administration, Oral; Amylases; Animals; Cholecystokinin; Duodenum; Eating; Esters; Fasting; Gabexate; Guanidines; Injections; Male; Organ Size; Pancreas; Protease Inhibitors; Proteins; Rats; Rats, Wistar; Secretin; Time Factors | 1993 |
Gastrin-releasing peptide and CCK after intraduodenal inhibition of proteases in dogs.
Topics: Animals; Cholecystokinin; Dogs; Esters; Feedback; Gabexate; Gastrin-Releasing Peptide; Guanidines; Pancreas; Peptides; Protease Inhibitors | 1994 |
Effect of bile salt binding or protease inactivation on plasma cholecystokinin and gallbladder responses to bombesin.
Topics: Adult; Bile Acids and Salts; Bombesin; Cholecystokinin; Cholestyramine Resin; Colestipol; Endopeptidases; Enzyme Activation; Esters; Feedback; Female; Gabexate; Gallbladder; Gastrins; Guanidines; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Protease Inhibitors; Protein Binding | 1994 |
Alcohol does not affect the trophic pancreatic effect of CCK and its plasma level in young rats.
Topics: Animals; Cholecystokinin; Esters; Ethanol; Gabexate; Guanidines; Hypertrophy; Male; Pancreas; Rats; Rats, Wistar | 1994 |
Characterization of the release of cholecystokinin from a murine neuroendocrine tumor cell line, STC-1.
Topics: Animals; Bombesin; Bucladesine; Calcimycin; Cholecystokinin; Colforsin; Cyclic AMP; Diterpenes; Dose-Response Relationship, Drug; Esters; Fatty Alcohols; Gabexate; Gene Expression; Guanidines; Mice; Tumor Cells, Cultured | 1994 |
Gastrin-releasing peptide and CCK after intraduodenal inhibition of proteases.
Topics: Animals; Cholecystokinin; Dogs; Duodenum; Esters; Fistula; Gabexate; Gastrin-Releasing Peptide; Gastrins; Guanidines; Immunoglobulins; Infusions, Intravenous; Pancreas; Peptides; Protease Inhibitors; Proteins | 1994 |
Loxiglumide (CR1505), a cholecystokinin antagonist, specifically inhibits the growth of human pancreatic cancer lines xenografted into nude mice.
Topics: Animals; Cell Division; Chloroquine; Cholecystokinin; DNA; Esters; Gabexate; Guanidines; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Organ Culture Techniques; Pancreatic Neoplasms; Proglumide; Sincalide; Transplantation, Heterologous | 1993 |
The effect of endogenous cholecystokinin released by bombesin and trypsin inhibitor on the regeneration of the pancreas.
Topics: Animals; Benzodiazepinones; Bombesin; Cholecystokinin; Devazepide; Esters; Gabexate; Guanidines; Male; Pancreas; Rats; Rats, Inbred F344; Regeneration; Time Factors; Trypsin Inhibitors | 1993 |
Feedback regulation of exocrine pancreatic secretion in dogs.
Topics: Animals; Atropine; Cholecystokinin; Dogs; Duodenum; Esters; Feedback; Food; Gabexate; Guanidines; Homeostasis; Kinetics; Lipase; Pancreas; Protease Inhibitors | 1993 |
Chronic oral administration of synthetic trypsin inhibitor camostate reduces amylase release from isolated rat pancreatic acini.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Administration, Oral; Amylases; Animals; Calcimycin; Carbachol; Cholecystokinin; Esters; Gabexate; Guanidines; In Vitro Techniques; Male; Pancreas; Rats; Rats, Wistar; Secretin; Sincalide; Tetradecanoylphorbol Acetate; Trypsin Inhibitors | 1995 |
Okadaic acid disrupts Golgi structure and impairs enzyme synthesis and secretion in the rat pancreas.
Topics: Animals; Cholecystokinin; Enzymes; Esters; Ethers, Cyclic; Gabexate; Golgi Apparatus; Guanidines; Male; Microscopy, Electron; Okadaic Acid; Pancreas; Protease Inhibitors; Protein Biosynthesis; Rats; Rats, Wistar | 1996 |
Effect of oral administration of protease inhibitor on pancreatic exocrine function in WBN/Kob rats with chronic pancreatitis.
Topics: Administration, Oral; Animals; Cholecystokinin; Chronic Disease; Disease Models, Animal; Esters; Gabexate; Guanidines; Humans; Male; Pancreas; Pancreatitis; Protease Inhibitors; Rats; Rats, Inbred Strains; Rats, Wistar | 1996 |
Rat pancreas after long-term treatment with the somatostatin analogue octreotide.
Topics: Animals; Cholecystokinin; Dose-Response Relationship, Drug; Esters; Gabexate; Guanidines; Male; Octreotide; Organ Size; Pancreas; Rats; Rats, Wistar; Time Factors | 1995 |
Accelerated gastric emptying of glucose in Zucker type 2 diabetic rats: role in postprandial hyperglycaemia.
Topics: Animals; Cholecystokinin; Diabetes Mellitus, Type 2; Esters; Gabexate; Gastric Emptying; Glucose; Guanidines; Hyperglycemia; Male; Postprandial Period; Rats; Rats, Zucker; Secretin; Trypsin Inhibitors | 1997 |
Effect of oral protease inhibitor administration on gallbladder motility in patients with mild chronic pancreatitis.
Topics: Administration, Oral; Adult; Aged; Cholecystokinin; Chronic Disease; Esters; Female; Gabexate; Gallbladder; Guanidines; Humans; Male; Middle Aged; Pancreatitis; Protease Inhibitors | 1997 |
Stimulative effects of saponin from kikyo-to, a Japanese herbal medicine, on pancreatic exocrine secretion of conscious rats.
Topics: Animals; Atropine; Cholecystokinin; Duodenum; Esters; Gabexate; Glycyrrhizic Acid; Guanidines; Japan; Male; Pancreas; Pancreatic Juice; Plant Extracts; Plant Roots; Plants, Medicinal; Proglumide; Rats; Rats, Wistar; Receptors, Cholecystokinin; Saponins; Triterpenes; Trypsin; Trypsin Inhibitors | 1997 |
CCK-, secretin-, and cholinergic-independent pancreatic fluid hypersecretion in protease inhibitor-treated rats.
Topics: Acetylcholine; Allylglycine; Animals; Benzamidines; Bicarbonates; Cell Division; Chlorides; Cholecystokinin; Esters; Gabexate; Guanidines; Male; Pancreas; Protease Inhibitors; Rats; Rats, Wistar; Secretin; Serine Proteinase Inhibitors | 1998 |
Different actions of CCK on pancreatic and gastric growth in the rat: effect of CCK(A) receptor blockade.
Topics: Animals; Ceruletide; Cholecystokinin; DNA; Esters; Gabexate; Gastric Mucosa; Guanidines; Male; Organ Size; Pancreas; Pentanoic Acids; Protease Inhibitors; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Stomach | 1998 |
Adaptation of the human pancreas to inhibition of luminal proteolytic activity.
Topics: Adaptation, Physiological; Adult; Amylases; Bicarbonates; Ceruletide; Cholecystokinin; Duodenum; Esters; Female; Food; Gabexate; Guanidines; Humans; Islets of Langerhans; Lipase; Male; Pancreas; Protease Inhibitors; Secretin; Trypsin; Ultrasonography | 1998 |
Acceleration of ulcer healing by cholecystokinin (CCK): role of CCK-A receptors, somatostatin, nitric oxide and sensory nerves.
Topics: Animals; Cholecystokinin; DNA Replication; Dopamine Agents; Esters; Gabexate; Gastric Mucosa; Gastrins; Guanidines; Hormone Antagonists; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pancreatin; Proglumide; Protease Inhibitors; Rats; Rats, Wistar; Receptors, Cholecystokinin; Regional Blood Flow; RNA, Messenger; Sensory Receptor Cells; Sincalide; Somatostatin; Stomach; Stomach Ulcer | 1999 |
Different effects of trypsin inhibitors on intestinal gene expression of secretin and on pancreatic bicarbonate secretion in CCK-A-receptor-deficient rats.
Topics: Allylglycine; Animals; Benzamidines; Bicarbonates; Blotting, Northern; Body Weight; Cholecystokinin; Eating; Esters; Gabexate; Gene Expression Regulation; Guanidines; Intestinal Mucosa; Intestines; Pancreas; Pancreatic Juice; Rats; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; RNA, Messenger; Secretin; Trypsin Inhibitor, Kunitz Soybean; Trypsin Inhibitors | 1999 |
Regulation of the initiation of pancreatic digestive enzyme protein synthesis by cholecystokinin in rat pancreas in vivo.
Topics: Animals; Carrier Proteins; Cholecystokinin; Digestion; Enzymes; Esters; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4G; Gabexate; Guanidines; Intracellular Signaling Peptides and Proteins; Male; Pancreas; Peptide Initiation Factors; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Trypsin Inhibitors | 2000 |
Does increased endogenous CCK interact with serotonin to reduce food intake in rats?
Topics: Animals; Anorexia; Body Weight; Cholecystokinin; Dose-Response Relationship, Drug; Drug Interactions; Eating; Esters; Fenfluramine; Gabexate; Guanidines; Male; Protease Inhibitors; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Time Factors; Trypsin Inhibitors | 2000 |
CCK-58 is the only detectable endocrine form of cholecystokinin in rat.
Topics: alpha-Amylases; Amino Acid Sequence; Animals; Buffers; Cholecystokinin; Chromatography, High Pressure Liquid; Esters; Gabexate; Guanidines; Hydrogen-Ion Concentration; Iodine Radioisotopes; Isotope Labeling; Molecular Sequence Data; Peptide Fragments; Plant Proteins; Rats; Sincalide; Trypsin Inhibitors; Tyrosine | 2003 |
Calcineurin mediates pancreatic growth in protease inhibitor-treated mice.
Topics: Animals; Calcineurin; Cholecystokinin; Cyclosporine; Enzyme Inhibitors; Esters; Gabexate; Guanidines; Male; Mice; Mice, Inbred ICR; Pancreas; Protease Inhibitors; Tacrolimus | 2004 |
Water and enzyme secretion are tightly coupled in pancreatic secretion stimulated by food or CCK-58 but not by CCK-8.
Topics: Animals; Bicarbonates; Body Water; Chlorides; Cholecystokinin; Esters; Food; Gabexate; Guanidines; Linear Models; Male; Pancreas; Rats; Rats, Wistar; Secretin; Sincalide; Time Factors | 2005 |
Induction of early response genes in trypsin inhibitor-induced pancreatic growth.
Topics: Activating Transcription Factor 2; Activating Transcription Factor 3; Animals; Carbamates; Cholecystokinin; Early Growth Response Transcription Factors; Esters; Extracellular Signal-Regulated MAP Kinases; Gabexate; Gene Expression; Guanidines; Immediate-Early Proteins; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Pancreas; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyrimidinones; Receptors, Cholecystokinin; Transcription Factor AP-1; Trypsin Inhibitors | 2007 |
Cholecystokinin activates pancreatic calcineurin-NFAT signaling in vitro and in vivo.
Topics: Animals; Calcineurin; Cell Line; Cell Nucleus; Cell Separation; Cholecystokinin; Esters; Gabexate; Green Fluorescent Proteins; Guanidines; Humans; Male; Mice; Mice, Inbred ICR; NFATC Transcription Factors; Pancreas, Exocrine; Protein Transport; Recombinant Fusion Proteins; Signal Transduction; Transcriptional Activation | 2008 |
CCK-induced pancreatic growth is not limited by mitogenic capacity in mice.
Topics: Adaptor Proteins, Signal Transducing; Administration, Oral; Animals; Autophagy; Carrier Proteins; Cell Cycle Proteins; Cholecystokinin; Cyclin-Dependent Kinase Inhibitor p21; DNA; Esters; Eukaryotic Initiation Factors; Gabexate; Gene Expression; Guanidines; Immunoblotting; Male; Mice; Mice, Inbred ICR; Microtubule-Associated Proteins; Mitosis; Organ Size; Pancreas; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Kinases; Proteins; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases; TOR Serine-Threonine Kinases; Ubiquitin-Protein Ligases | 2008 |
Activation of submucosal but not myenteric plexus of the gastrointestinal tract accompanies reduction of food intake by camostat.
Topics: Animals; Cholecystokinin; Devazepide; Eating; Esters; Gabexate; Gastrointestinal Tract; Guanidines; Hormone Antagonists; Models, Biological; Myenteric Plexus; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Solitary Nucleus; Submucous Plexus; Vagus Nerve | 2008 |
Regulator of calcineurin 1 controls growth plasticity of adult pancreas.
Topics: Animals; Calcineurin; Calcineurin Inhibitors; Calcium-Binding Proteins; Cell Proliferation; Cholecystokinin; Diet; Enzyme Inhibitors; Esters; Feedback, Physiological; Gabexate; Gene Expression Profiling; Gene Expression Regulation; Guanidines; Integrases; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred ICR; Mice, Transgenic; Muscle Proteins; NFATC Transcription Factors; NIH 3T3 Cells; Oligonucleotide Array Sequence Analysis; Organ Size; Pancreas; Pancreatic Elastase; Protease Inhibitors; Receptor, Cholecystokinin A; Receptors, Estrogen; Signal Transduction; Tacrolimus; Time Factors; Transfection | 2010 |
The short term satiety peptide cholecystokinin reduces meal size and prolongs intermeal interval.
Topics: Animals; Cholecystokinin; Dose-Response Relationship, Drug; Eating; Esters; Feeding Behavior; Gabexate; Guanidines; Male; Motor Activity; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Satiety Response; Sincalide; Time Factors | 2011 |
Duodenal myotomy blocks reduction of meal size and prolongation of intermeal interval by cholecystokinin.
Topics: Analysis of Variance; Animals; Autonomic Denervation; Cholecystokinin; Duodenum; Eating; Esters; Feeding Behavior; Gabexate; Gene Expression Regulation; Guanidines; Male; Muscle Denervation; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; RNA, Messenger; Sincalide; Time Factors | 2012 |
Effect of endogenous cholecystokinin on the course of acute pancreatitis in rats.
Topics: Administration, Oral; Animals; Biomarkers; Bombesin; Cell Proliferation; Cholecystokinin; Disease Models, Animal; DNA Replication; Esters; Gabexate; Guanidines; Hormone Antagonists; Insulin Resistance; Male; Pancreas; Pancreatic Function Tests; Pancreatitis; Proglumide; Rats, Wistar; Receptor, Cholecystokinin A; Recovery of Function; Taurocholic Acid; Time Factors | 2015 |
The feeding responses evoked by endogenous cholecystokinin are regulated by different gastrointestinal sites.
Topics: Animals; Celiac Artery; Cholecystokinin; Eating; Esters; Feeding Behavior; Femoral Artery; Gabexate; Guanidines; Male; Mesenteric Artery, Superior; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Time Factors | 2016 |