gabapentin and vigabatrin

gabapentin has been researched along with vigabatrin in 144 studies

Research

Studies (144)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.69)18.7374
1990's75 (52.08)18.2507
2000's47 (32.64)29.6817
2010's15 (10.42)24.3611
2020's6 (4.17)2.80

Authors

AuthorsStudies
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Campillo, NE; Guerra, A; Páez, JA1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Graves, NM; Leppik, IE2
Porter, RJ1
Despland, PA2
Kilpatrick, C1
Pimentel, J; Pinto, F1
Bloom, DS; O'Neill, BA; Trimble, MR1
Brodie, MJ; Leach, JP1
Devinsky, O; Luciano, D; Vazquez, B1
Beran, RG1
Upton, N1
Patsalos, PN; Sander, JW1
Buchanan, N1
Byers, VL1
Leppik, IE1
Harden, CL2
Ramsay, RE; Slater, JD1
Bialer, M1
Kochen, S1
Perucca, E1
Pellock, JM4
Legido, A1
Gaily, E; Iivanainen, M1
Loiseau, P1
Kelly, KM; Macdonald, RL1
Binnie, CD; Elwes, RD1
Cockerell, OC; Hughes, D1
McDonnell, GV; Morrow, JI1
Lönnecker, S; Paulus, W; Steinhoff, BJ; Ziemann, U1
Bourgeois, BF3
Haider, A; Haider, S; Tuchek, JM1
Lee, BI1
Duthie, T; Jackson, D1
Chadwick, DW; Kadir, ZA; Marson, AG1
Meldrum, BS1
Gram, L1
Mattson, RH1
Herranz, JL1
Grippo, J1
Appleton, RE1
Brodie, MJ; Wilson, EA1
Johannessen, SI1
Shorvon, S; Stefan, H1
Hosford, DA; Wang, Y1
Arbizu, T; Padró, L; Rovira, R1
Bhaumik, S; Branford, D; Duggirala, C; Ismail, IA1
Chapman, DP; Giles, WH1
Vossler, DG; Wyler, AR1
Dalby, NO; Nielsen, EB1
Krämer, G; Wad, N1
Bazil, CW; Pedley, TA1
Arzimanoglou, A; Baulac, M; Cavalcanti, D; Portal, JJ; Semah, F1
Petroff, OA; Rothman, DL1
Chadwick, DW; Hutton, JL; Kadir, ZA; Marson, AG1
Bauer, J; Elger, CE; Scherrmann, J; Widman, G1
Anderson, GD1
Köhling, R; Lücke, A; Mayer, T; Musshoff, U; Osterfeld, M; Schütte, W; Speckmann, EJ; Wolf, P1
Patsalos, PN; Ratnaraj, N1
Hildebrandt, J; Paulus, W; Tergau, F; Wischer, S; Ziemann, U1
Kerr, MP; Thijs, RD1
Selai, CE; Trimble, MR1
Feely, M1
Carvill, S; Cassidy, G; Clarke, D1
Patsalos, PN1
Ben-Menachem, E; Cramer, JA; Fisher, R; French, J; Mattson, RH1
Bernatik, J; Knorr, J; Stefan, H1
Eckstein-Ludwig, U; Fei, J; Schwarz, W1
Chadwick, DW; Fenwick, PB; Mawer, GE; Sander, JW; Wong, IC1
Elger, CE; Fernández, G1
Brodie, MJ2
Appleton, R; Pellock, JM1
Crawford, PM; Datta, PK1
Czuczwar, SJ1
Vajda, FJ1
Collins, TL; Mattson, RH; Petroff, OA1
Alenius, M; Frisén, L; Johannessen, SI; Larsson, S; Lindberger, M; Malmgren, K; Tomson, T1
Al-Hassan, MI; Bawazir, SA; Matar, KM; Nicholls, PJ; Tekle, A1
Bingmann, D; Bonnet, U; Hufnagel, A; Leniger, T; Wiemann, M1
Anderegg, G; Chollet, DF; Goumaz, L; Juliano, C1
Foletti, GB1
Johannessen, SI; Nakken, KO; Rytter, E1
Mawer, GE; Sander, JW; Wong, IC1
al-Madi, S; al-Zehouri, J; Belal, F1
Bandini, F; Castello, E; Mancardi, GL; Mazzella, L; Solaro, C1
Aldenkamp, AP1
Abdine, H; Al-Majed, A; Belal, F; Khalil, NY1
Annegers, JF; Beghi, E1
Errante, LD; Petroff, OA; Spencer, DD; Williamson, A1
Boon, PA; van Rijckevorsel, K1
Aribi, AM; Stringer, JL1
Bergin, AM; Connolly, M1
Koppatz, K; Krivanek, P; Turnheim, K1
Errante, LD; Petroff, OA1
Brodie, MJ; Butler, E; Forrest, G; Patsalos, PN; Ratnaraj, N; Sills, GJ1
Johannessen, SI; Larsson, S; Lindberger, M; Luhr, O; Tomson, T1
Johannessen, SI; Perucca, E1
Gau, CS; Lin, CJ; Liou, HH; Shyu, MK; Wu, SP1
Abdul-Zahra, E; Bataineh, H; Daoud, AS; Otoom, S1
Edelbroek, PM; Vermeij, TA1
Frediani, F1
Keegan, MB; Madden, D; McDonald, DG; McMenamin, JB; Najam, Y; Whooley, M1
Bernard, DR; Borrey, DC; Engelrelst, VI; Godderis, KO; Langlois, MR1
Price, MJ; Remak, E; Selai, CE; Trimble, MR1
Filip, M; Frankowska, M; Gołda, A; Przegaliński, E; Vetulani, J; Zaniewska, M2
Bonin, RP; Cheng, VY; Chiu, MW; MacDonald, JF; Newell, JG; Orser, BA1
Johannessen, SI; Tomson, T1
Assis, MA; Fonteles, MM; Freitas, RL; Freitas, RM; Pereira, MB; Silva, RF; Takahashi, RN1
Appleton, RE; Macleod, S1
Hwang, H; Kim, KJ1
Czuczwar, SJ; Luszczki, JJ; Patsalos, PN; Ratnaraj, N1
Arenz, N; Kirch, W; Oertel, R; Pietsch, J1
Andres-Mach, MM; Czuczwar, SJ; Dudra-Jastrzebska, M; Luszczki, JJ; Patsalos, PN; Ratnaraj, N; Sielski, M1
Ali, F; Cavanna, AE; McCorry, D; Rickards, HE1
Amore, M; Mandrioli, R; Mercolini, L; Raggi, MA1
Filip, D; Florek-Luszczki, M; Luszczki, JJ1
Czuczwar, SJ; Luszczki, JJ; Nieoczym, D; Socała, K; Wlaź, P1
Heinzlef, O; Monteil-Roch, I1
Chahbouni, A; den Burger, JC; Sinjewel, A; Swart, EL; Veldkamp, AI; Vos, RM; Wilhelm, AJ1
Martinc, B; Vovk, T1
Dotsikas, Y; Kostić, N; Malenović, A; Medenica, M1
Grabnar, I; Martinc, B; Roškar, R; Vovk, T1
Kumar, A; Niraj, RR; Piplani, S; Pushp, A; Saini, V1
Bursová, M; Čabala, R; Coufal, P; Hložek, T1
Androsova, G; Auce, P; Avbersek, A; Becker, F; Berghuis, B; Borghei, M; Campbell, E; Cavalleri, GL; Coppola, A; Craig, J; Delanty, N; Depondt, C; Francis, B; Koeleman, BPC; Krause, R; Kunz, WS; Lerche, H; Marson, AG; Sander, JW; Sills, GJ; Sisodiya, SM; Striano, P; Wassenaar, M; Wolking, S; Zara, F1
Bar-Klein, G; Friedman, A; Hameed, MQ; Jozwiak, S; Kaminski, RM; Klein, P; Klitgaard, H; Koepp, M; Löscher, W; Prince, DA; Rotenberg, A; Twyman, R; Vezzani, A; Wong, M1
Bialer, M; Franco, V; Odi, R; Perucca, E1
Alizadeh-Sani, M; Foroumadi, A; Hasanvand, Z; Jouyban, A; Mohammadian, E; Rahimpour, E1
Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T1
Du, Y; Jin, P; Tang, DQ; You, YX; Zhao, LL; Zhao, YL; Zheng, XX1
Chong, E; Kim, DJ; Kim, SM; Lee, SY; Oh, H1

Reviews

69 review(s) available for gabapentin and vigabatrin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antiepileptic medications in development.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:9

    Topics: Acetates; Amines; Aminocaproates; Animals; Anticonvulsants; Chemistry, Pharmaceutical; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Drugs, Investigational; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin

1991
[Current viewpoints in the treatment of epilepsies: role of new antiepileptics?].
    Praxis, 1995, Sep-19, Volume: 84, Issue:38

    Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Tolerance; Enzyme Inhibitors; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin

1995
[New antiepileptic medications].
    Acta medica portuguesa, 1995, Volume: 8, Issue:1

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin; Zonisamide

1995
Adjunctive therapy in epilepsy: a cost-effectiveness comparison of alternative treatment options.
    Seizure, 1995, Volume: 4, Issue:1

    Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Decision Support Techniques; Drug Therapy, Combination; Drug Tolerance; Electroencephalography; Epilepsy; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Long-Term Care; Triazines; Vigabatrin

1995
New antiepileptic drugs--an explosion of activity.
    Seizure, 1995, Volume: 4, Issue:1

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Approval; Drug Interactions; Drug Therapy, Combination; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Product Surveillance, Postmarketing; Treatment Outcome; Triazines; Vigabatrin

1995
New antiepileptic drugs for children: felbamate, gabapentin, lamotrigine, and vigabatrin.
    Journal of child neurology, 1994, Volume: 9 Suppl 1

    Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsies, Partial; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; United States; United States Food and Drug Administration; Vigabatrin

1994
Mechanisms of action of new antiepileptic drugs: rational design and serendipitous findings.
    Trends in pharmacological sciences, 1994, Volume: 15, Issue:12

    Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin

1994
Newer antiepileptic drugs. Towards an improved risk-benefit ratio.
    Drug safety, 1994, Volume: 11, Issue:1

    Topics: Acetamides; Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Piracetam; Propylene Glycols; Risk Factors; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

1994
New anti-epileptic drugs in the 1990s.
    Journal of paediatrics and child health, 1994, Volume: 30, Issue:4

    Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Cyclohexanecarboxylic Acids; Drugs, Investigational; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin

1994
Antiepileptic drugs in development: prospects for the near future.
    Epilepsia, 1994, Volume: 35 Suppl 4

    Topics: Acetates; Adult; Amines; Aminocaproates; Animals; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Approval; Drug Design; Drugs, Investigational; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin; Zonisamide

1994
New antiepileptic drugs.
    Neurology, 1994, Volume: 44, Issue:5

    Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Triazines; Vigabatrin

1994
Advances in pharmacotherapy: recent developments in the treatment of epilepsy.
    Journal of clinical pharmacy and therapeutics, 1993, Volume: 18, Issue:4

    Topics: Acetates; Amines; Aminocaproates; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin

1993
Antiepileptic drugs in clinical development.
    Epilepsy research. Supplement, 1993, Volume: 10

    Topics: Acetates; Amines; Aminocaproates; Anticonvulsants; Brain; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Structure-Activity Relationship; Synaptic Transmission; Tiagabine; Topiramate; Triazines; Vigabatrin

1993
Comparative pharmacokinetics of the newer antiepileptic drugs.
    Clinical pharmacokinetics, 1993, Volume: 24, Issue:6

    Topics: Acetamides; Acetates; Amines; Aminocaproates; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Felbamate; Flunarizine; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin

1993
Pharmacokinetic profile of topiramate in comparison with other new antiepileptic drugs.
    Epilepsia, 1996, Volume: 37 Suppl 2

    Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin

1996
Utilization of new antiepileptic drugs in children.
    Epilepsia, 1996, Volume: 37 Suppl 1

    Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin

1996
[Advances in the diagnostic and treatment of infantile epilepsy].
    Revista de neurologia, 1996, Volume: 24, Issue:130

    Topics: Acetates; Amines; Anticonvulsants; Brain; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Electroencephalography; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Magnetic Resonance Imaging; Phenylcarbamates; Propylene Glycols; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Triazines; Vigabatrin

1996
[Current anti-epilepsy drugs].
    Duodecim; laaketieteellinen aikakauskirja, 1995, Volume: 111, Issue:8

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin

1995
Antiepileptic drug mechanisms of action.
    Epilepsia, 1995, Volume: 36 Suppl 2

    Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Calcium Channels; Carbamazepine; Central Nervous System; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Phenytoin; Rats; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium Channels; Triazines; Trimethadione; Valproic Acid; Vigabatrin

1995
Clinical pharmacokinetics of newer antiepileptic drugs. Lamotrigine, vigabatrin, gabapentin and oxcarbazepine.
    Clinical pharmacokinetics, 1996, Volume: 30, Issue:6

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Tissue Distribution; Triazines; Vigabatrin

1996
A cost minimization study comparing vigabatrin, lamotrigine and gabapentin for the treatment of intractable partial epilepsy.
    Seizure, 1996, Volume: 5, Issue:2

    Topics: Acetates; Amines; Anticonvulsants; Cost Control; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Vigabatrin

1996
Important pharmacokinetic properties of antiepileptic drugs.
    Epilepsia, 1995, Volume: 36 Suppl 5

    Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Biopharmaceutics; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Intestinal Absorption; Lamotrigine; Oxcarbazepine; Topiramate; Triazines; Vigabatrin

1995
Seizure control: how to use the new antiepileptic drugs in older patients.
    Geriatrics, 1996, Volume: 51, Issue:9

    Topics: Acetates; Age Factors; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Patient Selection; Seizures; Triazines; Vigabatrin

1996
New antiepileptic drugs. II. Clinical use.
    Journal of Korean medical science, 1996, Volume: 11, Issue:4

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Felbamate; Forecasting; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin; Zonisamide

1996
New antiepileptic drugs: a systematic review of their efficacy and tolerability.
    BMJ (Clinical research ed.), 1996, Nov-09, Volume: 313, Issue:7066

    Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cross-Over Studies; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Male; Middle Aged; Nipecotic Acids; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide

1996
Update on the mechanism of action of antiepileptic drugs.
    Epilepsia, 1996, Volume: 37 Suppl 6

    Topics: 4-Aminobutyrate Transaminase; Acetamides; Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Membrane Potentials; Mice; Neurotransmitter Agents; Nipecotic Acids; Phenethylamines; Phenylcarbamates; Propylene Glycols; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tiagabine; Topiramate; Triazines; Vigabatrin

1996
Pharmacokinetics of new antiepileptic drugs.
    Epilepsia, 1996, Volume: 37 Suppl 6

    Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Carbamazepine; Cyclohexanecarboxylic Acids; Enzyme Induction; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin

1996
The role of the old and the new antiepileptic drugs in special populations: mental and multiple handicaps.
    Epilepsia, 1996, Volume: 37 Suppl 6

    Topics: Acetates; Amines; Anticonvulsants; Cerebral Palsy; Cyclohexanecarboxylic Acids; Disabled Persons; Drug Administration Schedule; Drug Interactions; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Phenylcarbamates; Polypharmacy; Propylene Glycols; Vigabatrin

1996
[Advantages and disadvantages of new antiepileptic drugs].
    Revista de neurologia, 1996, Volume: 24, Issue:135

    Topics: Acetates; Adrenocorticotropic Hormone; Amines; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Valproic Acid; Vigabatrin

1996
[Treatment of the epilepsy: new drugs].
    Revista de neurologia, 1996, Volume: 24, Issue:135

    Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin; Zonisamide

1996
The new antiepileptic drugs.
    Archives of disease in childhood, 1996, Volume: 75, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetates; Adolescent; Adult; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Pregnancy; Propylene Glycols; Randomized Controlled Trials as Topic; Triazines; Vigabatrin

1996
New antiepileptic drugs.
    Current opinion in pediatrics, 1996, Volume: 8, Issue:6

    Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin

1996
New antiepileptic drugs.
    Bailliere's clinical neurology, 1996, Volume: 5, Issue:4

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin

1996
Pharmacokinetics and interaction profile of topiramate: review and comparison with other newer antiepileptic drugs.
    Epilepsia, 1997, Volume: 38 Suppl 1

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Topiramate; Triazines; Vigabatrin

1997
Overview of the safety of newer antiepileptic drugs.
    Epilepsia, 1997, Volume: 38 Suppl 1

    Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin

1997
[New antiepileptic drugs].
    Revista de neurologia, 1997, Volume: 25, Issue:138

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenylcarbamates; Propylene Glycols; Vigabatrin

1997
Pharmacologic and dietary therapies in epilepsy: conventional treatments and recent advances.
    Southern medical journal, 1997, Volume: 90, Issue:5

    Topics: Acetates; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketone Bodies; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Triazines; Valproic Acid; Vigabatrin

1997
Recent advancements in epilepsy.
    Surgical neurology, 1997, Volume: 48, Issue:2

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Neurosurgery; Phenylcarbamates; Phenytoin; Pia Mater; Propylene Glycols; Temporal Lobe; Topiramate; Triazines; Vigabatrin

1997
Overview of lamotrigine and the new antiepileptic drugs: the challenge.
    Journal of child neurology, 1997, Volume: 12 Suppl 1

    Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Exanthema; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Treatment Outcome; Triazines; Valproic Acid; Vigabatrin

1997
Advances in the medical treatment of epilepsy.
    Annual review of medicine, 1998, Volume: 49

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diazepam; Drug Approval; Drug Design; Drug Interactions; Drug Resistance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Ketones; Lamotrigine; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Phenylcarbamates; Phenytoin; Prodrugs; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Valproic Acid; Vigabatrin

1998
Measuring human brain GABA in vivo: effects of GABA-transaminase inhibition with vigabatrin.
    Molecular neurobiology, 1998, Volume: 16, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Anticonvulsants; Brain; Brain Chemistry; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Neurological; Vigabatrin

1998
The new antiepileptic drugs: a systematic review of their efficacy and tolerability.
    Epilepsia, 1997, Volume: 38, Issue:8

    Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Male; Middle Aged; Randomized Controlled Trials as Topic; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide

1997
Aggravation of focal epileptic seizures by antiepileptic drugs.
    Epilepsia, 1998, Volume: 39 Suppl 3

    Topics: Acetates; Acute Disease; Adult; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Epilepsies, Partial; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenylcarbamates; Propylene Glycols; Vigabatrin

1998
A mechanistic approach to antiepileptic drug interactions.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:5

    Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin

1998
New antiepileptic drugs.
    Archives of neurology, 1998, Volume: 55, Issue:9

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Vigabatrin

1998
Fortnightly review: drug treatment of epilepsy.
    BMJ (Clinical research ed.), 1999, Jan-09, Volume: 318, Issue:7176

    Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Clobazam; Clonazepam; Cyclohexanecarboxylic Acids; Diethylcarbamazine; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Topiramate; Valproic Acid; Vigabatrin

1999
New antiepileptic drugs.
    Annals of clinical biochemistry, 1999, Volume: 36 ( Pt 1)

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Practice Guidelines as Topic; Topiramate; Triazines; Vigabatrin

1999
New antiepileptic drugs: comparison of key clinical trials.
    Epilepsia, 1999, Volume: 40, Issue:5

    Topics: Acetates; Amines; Anticonvulsants; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Placebos; Research Design; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin

1999
Options after the first antiepileptic drug has failed.
    Epilepsia, 1999, Volume: 40 Suppl 6

    Topics: Acetates; Amines; Anticonvulsants; Attitude to Health; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Quality of Life; Treatment Failure; Treatment Outcome; Valproic Acid; Vigabatrin

1999
Monostars: an aid to choosing an antiepileptic drug as monotherapy.
    Epilepsia, 1999, Volume: 40 Suppl 6

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Practice Patterns, Physicians'; Triazines; Valproic Acid; Vigabatrin

1999
Use of new antiepileptic drugs in the treatment of childhood epilepsy.
    Epilepsia, 1999, Volume: 40 Suppl 6

    Topics: Acetates; Adult; Age Factors; Amines; Anticonvulsants; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Spasms, Infantile; Tiagabine; Topiramate; Triazines; Vigabatrin

1999
Managing pediatric epilepsy syndromes with new antiepileptic drugs.
    Pediatrics, 1999, Volume: 104, Issue:5 Pt 1

    Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin

1999
[GABA-ergic system and antiepileptic drugs].
    Neurologia i neurochirurgia polska, 2000, Volume: 34 Suppl 1

    Topics: Acetates; Amines; Anticonvulsants; Binding, Competitive; Calcium Channels; Chloride Channels; Cyclohexanecarboxylic Acids; Epilepsy; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Humans; Nipecotic Acids; Receptors, GABA; Sodium Channels; Tiagabine; Vigabatrin

2000
New antiepileptic drugs.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2000, Volume: 7, Issue:2

    Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2000
Therapeutic safety monitoring: what to look for and when to look for it.
    Epilepsia, 2000, Volume: 41 Suppl 8

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Topiramate; Triazines; Valproic Acid; Vigabatrin

2000
[Adverse effects of antiepileptic agents].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2000, Oct-30, Volume: 120, Issue:26

    Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Clobazam; Cyclohexanecarboxylic Acids; Drug Utilization; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Norway; Piracetam; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2000
New antiepileptic drug therapies.
    Neurologic clinics, 2002, Volume: 20, Issue:4

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Phenytoin; Piracetam; Propylene Glycols; Thiazines; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2002
The ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come?
    Epileptic disorders : international epilepsy journal with videotape, 2003, Volume: 5 Suppl 1

    Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2003
Anticonvulsant drugs in primary headaches prophylaxis.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2004, Volume: 25 Suppl 3

    Topics: Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Oxcarbazepine; Piracetam; Topiramate; Triazines; Valproic Acid; Vigabatrin; Zonisamide

2004
Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed?
    Clinical pharmacokinetics, 2006, Volume: 45, Issue:11

    Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Pregabalin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2006
The new antiepileptic drugs.
    Archives of disease in childhood. Education and practice edition, 2007, Volume: 92, Issue:6

    Topics: Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsies, Partial; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Oxcarbazepine; Piracetam; Pregabalin; Topiramate; Triazines; Vigabatrin; Zonisamide

2007
New pharmacotherapies for pediatric seizures.
    Pediatric annals, 2004, Volume: 33, Issue:6

    Topics: Adolescent; Amines; Animals; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Pediatrics; Piracetam; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide

2004
Behavioral and cognitive effects of anti-epileptic drugs.
    Discovery medicine, 2010, Volume: 9, Issue:45

    Topics: Amines; Anticonvulsants; Antidepressive Agents; Behavior; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Lamotrigine; Neurotransmitter Agents; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Triazines; Vigabatrin

2010
[Pharmacological treatment of spasticity in multiple sclerosis].
    Revue neurologique, 2012, Volume: 168 Suppl 3

    Topics: Algorithms; Amines; Baclofen; Botulinum Toxins, Type A; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Double-Blind Method; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusion Pumps, Implantable; Injections, Spinal; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Nerve Block; Neuromuscular Agents; Randomized Controlled Trials as Topic; Spasm; Vigabatrin

2012
Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?
    Epilepsia, 2020, Volume: 61, Issue:3

    Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Atorvastatin; Brain Injuries, Traumatic; Ceftriaxone; Dibenzazepines; Drug Repositioning; Epilepsy; Epilepsy, Post-Traumatic; Erythropoietin; Fingolimod Hydrochloride; GABA Agents; Gabapentin; Humans; Immunologic Factors; Inflammation; Interleukin 1 Receptor Antagonist Protein; Isoflurane; Levetiracetam; Losartan; Neuroprotective Agents; Oxidative Stress; Pregabalin; Pyrrolidinones; Sirolimus; Stroke; Topiramate; Translational Research, Biomedical; Vigabatrin

2020
Bioequivalence and switchability of generic antiseizure medications (ASMs): A re-appraisal based on analysis of generic ASM products approved in Europe.
    Epilepsia, 2021, Volume: 62, Issue:2

    Topics: Anticonvulsants; Area Under Curve; Biological Variation, Individual; Dibenzazepines; Drug Substitution; Drugs, Generic; Europe; Gabapentin; Humans; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Pregabalin; Therapeutic Equivalency; Topiramate; Vigabatrin; Zonisamide

2021
Derivatization of γ-Amino Butyric Acid Analogues for Their Determination in the Biological Samples and Pharmaceutical Preparations: A Comprehensive Review.
    Critical reviews in analytical chemistry, 2022, Volume: 52, Issue:8

    Topics: Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Pharmaceutical Preparations; Pregabalin; Vigabatrin

2022
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
    Epileptic disorders : international epilepsy journal with videotape, 2022, 12-01, Volume: 24, Issue:6

    Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide

2022

Trials

6 trial(s) available for gabapentin and vigabatrin

ArticleYear
Pharmacological control of facilitatory I-wave interaction in the human motor cortex. A paired transcranial magnetic stimulation study.
    Electroencephalography and clinical neurophysiology, 1998, Volume: 109, Issue:4

    Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Central Nervous System Depressants; Cyclohexanecarboxylic Acids; Electric Stimulation; Ethanol; Evoked Potentials, Motor; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lorazepam; Male; Motor Cortex; Neural Inhibition; Phenobarbital; Transcranial Magnetic Stimulation; Triazines; Vigabatrin

1998
Adjunctive therapy in epilepsy with new antiepileptic drugs: is it of any value?
    Seizure, 1998, Volume: 7, Issue:5

    Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Clobazam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Humans; Lamotrigine; Male; Patient Compliance; Patient Satisfaction; Prospective Studies; Quality of Life; Triazines; Vigabatrin

1998
[Visual field defects due to antiepileptic drugs].
    Der Nervenarzt, 1999, Volume: 70, Issue:6

    Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Vigabatrin; Vision Disorders; Visual Field Tests; Visual Fields

1999
Gabapentin versus vigabatrin as first add-on for patients with partial seizures that failed to respond to monotherapy: a randomized, double-blind, dose titration study. GREAT Study Investigators Group. Gabapentin in Refractory Epilepsy Add-on Treatment.
    Epilepsia, 2000, Volume: 41, Issue:10

    Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Research Design; Retrospective Studies; Treatment Outcome; Vigabatrin

2000
Gabapentin but not vigabatrin is effective in the treatment of acquired nystagmus in multiple sclerosis: How valid is the GABAergic hypothesis?
    Journal of neurology, neurosurgery, and psychiatry, 2001, Volume: 71, Issue:1

    Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Electrooculography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Nystagmus, Physiologic; Vigabatrin; Visual Acuity

2001
Serum concentrations and effects of gabapentin and vigabatrin: observations from a dose titration study.
    Therapeutic drug monitoring, 2003, Volume: 25, Issue:4

    Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Monitoring; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Vigabatrin

2003

Other Studies

69 other study(ies) available for gabapentin and vigabatrin

ArticleYear
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Mechanisms of action of new antiepileptic drugs.
    Epilepsia, 1989, Volume: 30 Suppl 1

    Topics: Acetamides; Acetates; Amines; Aminocaproates; Aminopyridines; Anti-Anxiety Agents; Anticonvulsants; Aspartic Acid; Benzodiazepines; Benzodiazepinones; Clobazam; Cyclohexanecarboxylic Acids; Dibenzocycloheptenes; Dizocilpine Maleate; Epilepsy; Felbamate; Flumazenil; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Imidazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Receptors, GABA-A; Triazines; Vigabatrin

1989
The role of newer anticonvulsants in the management of epilepsy.
    Australian and New Zealand journal of medicine, 1995, Volume: 25, Issue:2

    Topics: Acetates; Amines; Anticonvulsants; Australia; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Vigabatrin

1995
New antiepileptic medications.
    The Medical journal of Australia, 1995, Feb-06, Volume: 162, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Acetamides; Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Tiagabine; Triazines; Vigabatrin

1995
Novel antiepileptic drugs: nursing implications.
    The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 1993, Volume: 25, Issue:6

    Topics: Acetates; Amines; Aminocaproates; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Approval; Drug Interactions; Drug Monitoring; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Patient Care Planning; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin

1993
Costing of antiepileptic drugs.
    Lancet (London, England), 1996, Jan-27, Volume: 347, Issue:8996

    Topics: Acetates; Amines; Anticonvulsants; Argentina; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Costs; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin

1996
[Current role of novel antiepileptics in the treatment of epilepsies].
    Praxis, 1996, Jan-23, Volume: 85, Issue:4

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Resistance; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin

1996
[New medical treatment of epilepsy].
    Presse medicale (Paris, France : 1983), 1996, Mar-23, Volume: 25, Issue:10

    Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Costs; Epilepsy; France; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Middle Aged; Triazines; Vigabatrin

1996
An audit of the new antiepileptic drugs in clinical neurological practice.
    Seizure, 1996, Volume: 5, Issue:2

    Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Treatment Outcome; Triazines; Vigabatrin

1996
Effects of antiepileptic drugs on motor cortex excitability in humans: a transcranial magnetic stimulation study.
    Annals of neurology, 1996, Volume: 40, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Acetates; Adult; Amines; Anticonvulsants; Baclofen; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Differential Threshold; Enzyme Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Motor Cortex; Physical Stimulation; Transcranial Magnetic Stimulation; Vigabatrin

1996
If comparisons can be odious, so can assumptions.
    Seizure, 1996, Volume: 5, Issue:3

    Topics: Acetates; Amines; Anticonvulsants; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Quality of Life; Treatment Outcome; Triazines; Vigabatrin

1996
Utility of the lethargic (lh/lh) mouse model of absence seizures in predicting the effects of lamotrigine, vigabatrin, tiagabine, gabapentin, and topiramate against human absence seizures.
    Epilepsia, 1997, Volume: 38, Issue:4

    Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Absence; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Mice; Nipecotic Acids; Tiagabine; Topiramate; Triazines; Vigabatrin

1997
A naturalistic study of the use of vigabatrin, lamotrigine and gabapentin in adults with learning disabilities.
    Seizure, 1997, Volume: 6, Issue:2

    Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Comorbidity; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Lamotrigine; Learning Disabilities; Male; Middle Aged; Retrospective Studies; Seizures; Social Behavior Disorders; Substance-Related Disorders; Treatment Outcome; Triazines; Vigabatrin

1997
Comparison of the preclinical anticonvulsant profiles of tiagabine, lamotrigine, gabapentin and vigabatrin.
    Epilepsy research, 1997, Volume: 28, Issue:1

    Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Lamotrigine; Male; Mice; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Tiagabine; Triazines; Vigabatrin

1997
Sensitive high-performance liquid chromatographic method with fluorometric detection for the simultaneous determination of gabapentin and vigabatrin in serum and urine.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, Jan-23, Volume: 705, Issue:1

    Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Sensitivity and Specificity; Spectrometry, Fluorescence; Vigabatrin

1998
Gabapentin add-on therapy with adaptable dosages in 610 patients with partial epilepsy: an open, observational study. The French Gabapentin Collaborative Group.
    Seizure, 1998, Volume: 7, Issue:1

    Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome; Vigabatrin

1998
Gabapentin potentiation of the antiepileptic efficacy of vigabatrin in an in vitro model of epilepsy.
    British journal of pharmacology, 1998, Volume: 124, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Animals; Anticonvulsants; Bicuculline; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Epilepsy; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium Deficiency; Polypharmacy; Seizures; Vigabatrin

1998
A high-performance liquid chromatography micromethod for the simultaneous determination of vigabatrin and gabapentin in serum.
    Therapeutic drug monitoring, 1998, Volume: 20, Issue:4

    Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Microchemistry; Sensitivity and Specificity; Vigabatrin

1998
The outcome of prescribing novel anticonvulsants in an outpatient setting: factors affecting response to medication.
    Seizure, 1998, Volume: 7, Issue:5

    Topics: Acetates; Adolescent; Adult; Ambulatory Care; Amines; Anticonvulsants; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Drug Prescriptions; Epilepsy; Female; Follow-Up Studies; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Patient Compliance; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Wales

1998
The management of epilepsy in a hospital for people with a learning disability.
    Seizure, 1999, Volume: 8, Issue:3

    Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Utilization; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Hospitals, Psychiatric; Humans; Lamotrigine; Learning Disabilities; Male; Middle Aged; Phenobarbital; Triazines; United Kingdom; Vigabatrin

1999
Inhibition of uptake, steady-state currents, and transient charge movements generated by the neuronal GABA transporter by various anticonvulsant drugs.
    British journal of pharmacology, 1999, Volume: 128, Issue:1

    Topics: Acetates; Amines; Animals; Anticonvulsants; Binding Sites; Biological Transport; Carrier Proteins; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Conductivity; Female; GABA Plasma Membrane Transport Proteins; Gabapentin; gamma-Aminobutyric Acid; Kinetics; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Mice; Nipecotic Acids; Oocytes; Organic Anion Transporters; Patch-Clamp Techniques; Tiagabine; Valproic Acid; Vigabatrin; Xenopus laevis

1999
The long-term use of gabapentin, lamotrigine, and vigabatrin in patients with chronic epilepsy.
    Epilepsia, 1999, Volume: 40, Issue:10

    Topics: Acetates; Ambulatory Care; Amines; Anticonvulsants; Chronic Disease; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Longitudinal Studies; Medical Records; Multicenter Studies as Topic; Patient Dropouts; Pharmacoepidemiology; Proportional Hazards Models; Retrospective Studies; Survival Analysis; Treatment Outcome; Triazines; United Kingdom; Vigabatrin

1999
Refractory epilepsy: treatment with new antiepileptic drugs.
    Seizure, 2000, Volume: 9, Issue:1

    Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Nipecotic Acids; Patient Dropouts; Retrospective Studies; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin

2000
A comparison of four new antiepileptic medications.
    Seizure, 2000, Volume: 9, Issue:4

    Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Medical Records; Middle Aged; Retrospective Studies; Survival Analysis; Topiramate; Treatment Outcome; Triazines; Vigabatrin

2000
Effect of vigabatrin and gabapentin on phenytoin pharmacokinetics in the dog.
    Pharmacological research, 2000, Volume: 42, Issue:6

    Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dogs; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Male; Phenytoin; Vigabatrin

2000
Different effects of GABAergic anticonvulsants on 4-aminopyridine-induced spontaneous GABAergic hyperpolarizations of hippocampal pyramidal cells--implication for their potency in migraine therapy.
    Cephalalgia : an international journal of headache, 2000, Volume: 20, Issue:6

    Topics: 4-Aminopyridine; Acetates; Amines; Analgesics; Animals; Anticonvulsants; Convulsants; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Humans; Membrane Potentials; Migraine Disorders; Nipecotic Acids; Pyramidal Cells; Tiagabine; Time Factors; Valproic Acid; Vigabatrin

2000
Fast isocratic high-performance liquid chromatographic assay method for the simultaneous determination of gabapentin and vigabatrin in human serum.
    Journal of chromatography. B, Biomedical sciences and applications, 2000, Sep-15, Volume: 746, Issue:2

    Topics: Acetates; Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Vigabatrin

2000
[Clinical utilization of new anti-epileptic agents].
    Revue medicale de la Suisse romande, 2000, Volume: 120, Issue:9

    Topics: Acetates; Amines; Anemia, Aplastic; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Visual Fields

2000
Adverse event monitoring in lamotrigine patients: a pharmacoepidemiologic study in the United Kingdom.
    Epilepsia, 2001, Volume: 42, Issue:2

    Topics: Acetates; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Death, Sudden; Drug Eruptions; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Lamotrigine; Male; Middle Aged; Neurotoxicity Syndromes; Pharmacoepidemiology; Product Surveillance, Postmarketing; Triazines; United Kingdom; Vigabatrin

2001
Determination of the antiepileptics vigabatrin and gabapentin in dosage forms and biological fluids using Hantzsch reaction.
    Arzneimittel-Forschung, 2001, Volume: 51, Issue:2

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fluorescent Dyes; Gabapentin; gamma-Aminobutyric Acid; Humans; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tablets; Vigabatrin

2001
Effects of antiepileptic drugs on cognition.
    Epilepsia, 2001, Volume: 42 Suppl 1

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; Triazoles; Vigabatrin

2001
Management strategies for refractory localization-related seizures.
    Epilepsia, 2001, Volume: 42 Suppl 3

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Practice Patterns, Physicians'; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin

2001
Spectrofluorimetric determination of vigabatrin and gabapentin in urine and dosage forms through derivatization with fluorescamine.
    Journal of pharmaceutical and biomedical analysis, 2002, Jan-01, Volume: 27, Issue:1-2

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dosage Forms; Fluorescamine; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Molecular Structure; Reproducibility of Results; Spectrometry, Fluorescence; Vigabatrin

2002
Pregnancy registries in epilepsy.
    Epilepsia, 2001, Volume: 42, Issue:11

    Topics: Abnormalities, Drug-Induced; Acetates; Amines; Anticonvulsants; Australia; Cross-Cultural Comparison; Cyclohexanecarboxylic Acids; Data Collection; Databases as Topic; Epilepsy; Europe; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; India; Infant, Newborn; International Cooperation; Lamotrigine; Pregnancy; Pregnancy Complications; Product Surveillance, Postmarketing; Registries; Severity of Illness Index; Triazines; United Kingdom; Vigabatrin

2001
Gabapentin and vigabatrin increase GABA in the human neocortical slice.
    Epilepsy research, 2002, Volume: 49, Issue:3

    Topics: Acetates; Adolescent; Adult; Amines; Animals; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Male; Middle Aged; Neocortex; Rats; Rats, Sprague-Dawley; Vigabatrin

2002
The 'number needed to treat' with levetiracetam (LEV): comparison with the other new antiepileptic drugs (AEDs).
    Seizure, 2002, Volume: 11 Suppl A

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2002
Modulation of the in vivo effects of gabapentin by vigabatrin and SKF89976A.
    Epilepsy research, 2002, Volume: 52, Issue:2

    Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dentate Gyrus; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Male; Neural Inhibition; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Reaction Time; Vigabatrin

2002
Simultaneous isocratic HPLC determination of vigabatrin and gabapentin in human plasma by dansyl derivatization.
    Therapeutic drug monitoring, 2003, Volume: 25, Issue:3

    Topics: Acetates; Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dansyl Compounds; Gabapentin; gamma-Aminobutyric Acid; Humans; Vigabatrin

2003
Acute effects of gabapentin and pregabalin on rat forebrain cellular GABA, glutamate, and glutamine concentrations.
    Seizure, 2003, Volume: 12, Issue:5

    Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Injections, Intraperitoneal; Magnetic Resonance Spectroscopy; Male; Neurons; Pregabalin; Prosencephalon; Rats; Rats, Long-Evans; Vigabatrin

2003
Vigabatrin, but not gabapentin or topiramate, produces concentration-related effects on enzymes and intermediates of the GABA shunt in rat brain and retina.
    Epilepsia, 2003, Volume: 44, Issue:7

    Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Fructose; Gabapentin; gamma-Aminobutyric Acid; Male; Rats; Rats, Sprague-Dawley; Retina; Topiramate; Vigabatrin; Visual Fields

2003
Interaction between anticonvulsants and human placental carnitine transporter.
    Epilepsia, 2004, Volume: 45, Issue:3

    Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techniques; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Models, Biological; Nipecotic Acids; Organic Cation Transport Proteins; Phenytoin; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Proteins; Solute Carrier Family 22 Member 5; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin

2004
The effect of Vigabatrin, Lamotrigine and Gabapentin on the fertility, weights, sex hormones and biochemical profiles of male rats.
    Neuro endocrinology letters, 2004, Volume: 25, Issue:3

    Topics: Amines; Analgesics; Animals; Antimanic Agents; Body Weight; Cyclohexanecarboxylic Acids; Female; Fertility; Follicle Stimulating Hormone; Gabapentin; gamma-Aminobutyric Acid; Lamotrigine; Male; Organ Size; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Testosterone; Triazines; Vigabatrin

2004
Simultaneous high-performance liquid chromatographic analysis of pregabalin, gabapentin and vigabatrin in human serum by precolumn derivatization with o-phtaldialdehyde and fluorescence detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004, Oct-25, Volume: 810, Issue:2

    Topics: Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Gabapentin; gamma-Aminobutyric Acid; Humans; Indicators and Reagents; o-Phthalaldehyde; Pregabalin; Reference Standards; Reproducibility of Results; Solutions; Specimen Handling; Spectrometry, Fluorescence; Vigabatrin

2004
The use of lamotrigine, vigabatrin and gabapentin as add-on therapy in intractable epilepsy of childhood.
    Seizure, 2005, Volume: 14, Issue:2

    Topics: Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Tolerance; Epilepsies, Partial; Epilepsy, Generalized; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Infant, Newborn; Lamotrigine; Male; Retrospective Studies; Triazines; Vigabatrin

2005
Quantitative determination of vigabatrin and gabapentin in human serum by gas chromatography-mass spectrometry.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 354, Issue:1-2

    Topics: Amines; Calibration; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Sensitivity and Specificity; Vigabatrin

2005
Evaluation of health status in epilepsy using the EQ-5D questionnaire: a prospective, observational, 6-month study of adjunctive therapy with anti-epileptic drugs.
    Current medical research and opinion, 2005, Volume: 21, Issue:5

    Topics: Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Prospective Studies; Secondary Prevention; Sickness Impact Profile; Surveys and Questionnaires; Topiramate; Triazines; Vigabatrin

2005
Various GABA-mimetic drugs differently affect cocaine-evoked hyperlocomotion and sensitization.
    European journal of pharmacology, 2006, Jul-17, Volume: 541, Issue:3

    Topics: Amines; Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agents; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Male; Motor Activity; Nipecotic Acids; Rats; Rats, Wistar; Tiagabine; Vigabatrin

2006
Gabapentin increases a tonic inhibitory conductance in hippocampal pyramidal neurons.
    Anesthesiology, 2006, Volume: 105, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Amines; Analgesics; Animals; Blotting, Western; Cyclohexanecarboxylic Acids; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Mice; Neural Conduction; Patch-Clamp Techniques; Pregnancy; Pyramidal Cells; Receptors, GABA-A; Receptors, GABA-B; Somatosensory Cortex; Synapses; Vigabatrin

2006
Diverse effects of GABA-mimetic drugs on cocaine-evoked self-administration and discriminative stimulus effects in rats.
    Psychopharmacology, 2007, Volume: 192, Issue:1

    Topics: Amines; Animals; Behavior, Animal; Cocaine; Cyclohexanecarboxylic Acids; Discrimination Learning; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Nipecotic Acids; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Tiagabine; Vigabatrin

2007
Study pharmacologic of the GABAergic and glutamatergic drugs on seizures and status epilepticus induced by pilocarpine in adult Wistar rats.
    Neuroscience letters, 2007, Jun-04, Volume: 419, Issue:3

    Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Ketamine; Male; Muscarinic Agonists; N-Methylaspartate; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Receptors, GABA; Receptors, Neurotransmitter; Seizures; Status Epilepticus; Vigabatrin

2007
New antiepileptic drugs in pediatric epilepsy.
    Brain & development, 2008, Volume: 30, Issue:9

    Topics: Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Pediatrics; Phenylcarbamates; Piracetam; Practice Guidelines as Topic; Propylene Glycols; Topiramate; Triazines; Vigabatrin

2008
Isobolographic and behavioral characterizations of interactions between vigabatrin and gabapentin in two experimental models of epilepsy.
    European journal of pharmacology, 2008, Oct-24, Volume: 595, Issue:1-3

    Topics: Amines; Animals; Anticonvulsants; Behavior, Animal; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Muscle Strength; Pentylenetetrazole; Psychomotor Performance; Seizures; Vigabatrin

2008
Simultaneous determination of three anticonvulsants using hydrophilic interaction LC-MS.
    Journal of separation science, 2009, Volume: 32, Issue:2

    Topics: Amines; Anticonvulsants; Calibration; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Pregabalin; Solutions; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Temperature; Vigabatrin; Water

2009
Pharmacodynamic and pharmacokinetic interaction profiles of levetiracetam in combination with gabapentin, tiagabine and vigabatrin in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis.
    European journal of pharmacology, 2009, Mar-01, Volume: 605, Issue:1-3

    Topics: Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Interactions; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Levetiracetam; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Piracetam; Seizures; Tiagabine; Tissue Distribution; Vigabatrin

2009
Simultaneous HPLC-F analysis of three recent antiepileptic drugs in human plasma.
    Journal of pharmaceutical and biomedical analysis, 2010, Sep-21, Volume: 53, Issue:1

    Topics: Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dansyl Compounds; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Spectrometry, Fluorescence; Topiramate; Vigabatrin

2010
Interactions of pregabalin with gabapentin, levetiracetam, tiagabine and vigabatrin in the mouse maximal electroshock-induced seizure model: a type II isobolographic analysis.
    Epilepsy research, 2012, Volume: 98, Issue:2-3

    Topics: Amines; Animals; Anticonvulsants; Avoidance Learning; Confidence Intervals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Levetiracetam; Male; Mice; Motor Activity; Piracetam; Pregabalin; Seizures; Vigabatrin

2012
Sildenafil influences the anticonvulsant activity of vigabatrin and gabapentin in the timed pentylenetetrazole infusion test in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2012, Oct-01, Volume: 39, Issue:1

    Topics: Amines; Animals; Anticonvulsants; Avoidance Learning; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Male; Mice; Motor Skills; Pentylenetetrazole; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Seizures; Sildenafil Citrate; Sulfones; Vigabatrin

2012
Rapid quantification of gabapentin, pregabalin, and vigabatrin in human serum by ultraperformance liquid chromatography with mass-spectrometric detection.
    Therapeutic drug monitoring, 2013, Volume: 35, Issue:1

    Topics: Amines; Anticonvulsants; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Tandem Mass Spectrometry; Vigabatrin

2013
A simple high-throughput method for determination of antiepileptic analogues of γ-aminobutyric acid in pharmaceutical dosage forms using microplate fluorescence reader.
    Chemical & pharmaceutical bulletin, 2013, Volume: 61, Issue:10

    Topics: Amines; Anticonvulsants; Capsules; Cyclohexanecarboxylic Acids; Fluorescamine; Gabapentin; gamma-Aminobutyric Acid; High-Throughput Screening Assays; Pharmaceutical Preparations; Pregabalin; Spectrometry, Fluorescence; Tablets; Temperature; Vigabatrin

2013
Effects of derivatization reagents consisting of n-alkyl chloroformate/n-alcohol combinations in LC-ESI-MS/MS analysis of zwitterionic antiepileptic drugs.
    Talanta, 2013, Nov-15, Volume: 116

    Topics: 1-Propanol; Amines; Anticonvulsants; Butanols; Cyclohexanecarboxylic Acids; Esters; Ethanol; Formates; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Methanol; Pregabalin; Solutions; Spectrometry, Mass, Electrospray Ionization; Vigabatrin

2013
Simultaneous determination of gabapentin, pregabalin, vigabatrin, and topiramate in plasma by HPLC with fluorescence detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, Jul-01, Volume: 962

    Topics: Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Fluorescence; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Pregabalin; Solid Phase Extraction; Topiramate; Vigabatrin

2014
Homology modelling and molecular docking studies of human placental cadherin protein for its role in teratogenic effects of anti-epileptic drugs.
    Computational biology and chemistry, 2016, Volume: 60

    Topics: Acetamides; Amines; Animals; Anticonvulsants; Binding Sites; Cadherins; Calcium; Cations, Divalent; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Pregabalin; Pregnancy; Sequence Homology; Teratogens; Vigabatrin

2016
Gabapentin, Pregabalin and Vigabatrin Quantification in Human Serum by GC-MS After Hexyl Chloroformate Derivatization.
    Journal of analytical toxicology, 2016, Volume: 40, Issue:9

    Topics: Amines; Anticonvulsants; Calibration; Computer-Aided Design; Cyclohexanecarboxylic Acids; Formates; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Pregabalin; Vigabatrin

2016
Comparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis.
    Epilepsia, 2017, Volume: 58, Issue:10

    Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Ataxia; Benzodiazepines; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Databases, Factual; Diplopia; Dizziness; Epilepsy, Temporal Lobe; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Humans; Lamotrigine; Lethargy; Male; Middle Aged; Oxcarbazepine; Pregabalin; Retrospective Studies; Sclerosis; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Vertigo; Vigabatrin; Vision Disorders; Young Adult

2017
A simple and easy non-derivatization gas chromatography-mass spectrometry method for simultaneous quantification of valproic acid, gabapentin, pregabalin, and vigabatrin in human plasma.
    Journal of separation science, 2023, Volume: 46, Issue:2

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Pregabalin; Valproic Acid; Vigabatrin

2023
Quantification of Gabapentin, Lacosamide, Perampanel, Pregabalin, Rufinamide, and Vigabatrin in Serum Using Liquid Chromatography-Tandem Mass Spectrometry.
    Methods in molecular biology (Clifton, N.J.), 2024, Volume: 2737

    Topics: Anticonvulsants; Chromatography, Liquid; Gabapentin; Lacosamide; Pregabalin; Tandem Mass Spectrometry; Vigabatrin

2024