gabapentin has been researched along with vigabatrin in 144 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.69) | 18.7374 |
| 1990's | 75 (52.08) | 18.2507 |
| 2000's | 47 (32.64) | 29.6817 |
| 2010's | 15 (10.42) | 24.3611 |
| 2020's | 6 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Graves, NM; Leppik, IE | 2 |
| Porter, RJ | 1 |
| Despland, PA | 2 |
| Kilpatrick, C | 1 |
| Pimentel, J; Pinto, F | 1 |
| Bloom, DS; O'Neill, BA; Trimble, MR | 1 |
| Brodie, MJ; Leach, JP | 1 |
| Devinsky, O; Luciano, D; Vazquez, B | 1 |
| Beran, RG | 1 |
| Upton, N | 1 |
| Patsalos, PN; Sander, JW | 1 |
| Buchanan, N | 1 |
| Byers, VL | 1 |
| Leppik, IE | 1 |
| Harden, CL | 2 |
| Ramsay, RE; Slater, JD | 1 |
| Bialer, M | 1 |
| Kochen, S | 1 |
| Perucca, E | 1 |
| Pellock, JM | 4 |
| Legido, A | 1 |
| Gaily, E; Iivanainen, M | 1 |
| Loiseau, P | 1 |
| Kelly, KM; Macdonald, RL | 1 |
| Binnie, CD; Elwes, RD | 1 |
| Cockerell, OC; Hughes, D | 1 |
| McDonnell, GV; Morrow, JI | 1 |
| Lönnecker, S; Paulus, W; Steinhoff, BJ; Ziemann, U | 1 |
| Bourgeois, BF | 3 |
| Haider, A; Haider, S; Tuchek, JM | 1 |
| Lee, BI | 1 |
| Duthie, T; Jackson, D | 1 |
| Chadwick, DW; Kadir, ZA; Marson, AG | 1 |
| Meldrum, BS | 1 |
| Gram, L | 1 |
| Mattson, RH | 1 |
| Herranz, JL | 1 |
| Grippo, J | 1 |
| Appleton, RE | 1 |
| Brodie, MJ; Wilson, EA | 1 |
| Johannessen, SI | 1 |
| Shorvon, S; Stefan, H | 1 |
| Hosford, DA; Wang, Y | 1 |
| Arbizu, T; Padró, L; Rovira, R | 1 |
| Bhaumik, S; Branford, D; Duggirala, C; Ismail, IA | 1 |
| Chapman, DP; Giles, WH | 1 |
| Vossler, DG; Wyler, AR | 1 |
| Dalby, NO; Nielsen, EB | 1 |
| Krämer, G; Wad, N | 1 |
| Bazil, CW; Pedley, TA | 1 |
| Arzimanoglou, A; Baulac, M; Cavalcanti, D; Portal, JJ; Semah, F | 1 |
| Petroff, OA; Rothman, DL | 1 |
| Chadwick, DW; Hutton, JL; Kadir, ZA; Marson, AG | 1 |
| Bauer, J; Elger, CE; Scherrmann, J; Widman, G | 1 |
| Anderson, GD | 1 |
| Köhling, R; Lücke, A; Mayer, T; Musshoff, U; Osterfeld, M; Schütte, W; Speckmann, EJ; Wolf, P | 1 |
| Patsalos, PN; Ratnaraj, N | 1 |
| Hildebrandt, J; Paulus, W; Tergau, F; Wischer, S; Ziemann, U | 1 |
| Kerr, MP; Thijs, RD | 1 |
| Selai, CE; Trimble, MR | 1 |
| Feely, M | 1 |
| Carvill, S; Cassidy, G; Clarke, D | 1 |
| Patsalos, PN | 1 |
| Ben-Menachem, E; Cramer, JA; Fisher, R; French, J; Mattson, RH | 1 |
| Bernatik, J; Knorr, J; Stefan, H | 1 |
| Eckstein-Ludwig, U; Fei, J; Schwarz, W | 1 |
| Chadwick, DW; Fenwick, PB; Mawer, GE; Sander, JW; Wong, IC | 1 |
| Elger, CE; Fernández, G | 1 |
| Brodie, MJ | 2 |
| Appleton, R; Pellock, JM | 1 |
| Crawford, PM; Datta, PK | 1 |
| Czuczwar, SJ | 1 |
| Vajda, FJ | 1 |
| Collins, TL; Mattson, RH; Petroff, OA | 1 |
| Alenius, M; Frisén, L; Johannessen, SI; Larsson, S; Lindberger, M; Malmgren, K; Tomson, T | 1 |
| Al-Hassan, MI; Bawazir, SA; Matar, KM; Nicholls, PJ; Tekle, A | 1 |
| Bingmann, D; Bonnet, U; Hufnagel, A; Leniger, T; Wiemann, M | 1 |
| Anderegg, G; Chollet, DF; Goumaz, L; Juliano, C | 1 |
| Foletti, GB | 1 |
| Johannessen, SI; Nakken, KO; Rytter, E | 1 |
| Mawer, GE; Sander, JW; Wong, IC | 1 |
| al-Madi, S; al-Zehouri, J; Belal, F | 1 |
| Bandini, F; Castello, E; Mancardi, GL; Mazzella, L; Solaro, C | 1 |
| Aldenkamp, AP | 1 |
| Abdine, H; Al-Majed, A; Belal, F; Khalil, NY | 1 |
| Annegers, JF; Beghi, E | 1 |
| Errante, LD; Petroff, OA; Spencer, DD; Williamson, A | 1 |
| Boon, PA; van Rijckevorsel, K | 1 |
| Aribi, AM; Stringer, JL | 1 |
| Bergin, AM; Connolly, M | 1 |
| Koppatz, K; Krivanek, P; Turnheim, K | 1 |
| Errante, LD; Petroff, OA | 1 |
| Brodie, MJ; Butler, E; Forrest, G; Patsalos, PN; Ratnaraj, N; Sills, GJ | 1 |
| Johannessen, SI; Larsson, S; Lindberger, M; Luhr, O; Tomson, T | 1 |
| Johannessen, SI; Perucca, E | 1 |
| Gau, CS; Lin, CJ; Liou, HH; Shyu, MK; Wu, SP | 1 |
| Abdul-Zahra, E; Bataineh, H; Daoud, AS; Otoom, S | 1 |
| Edelbroek, PM; Vermeij, TA | 1 |
| Frediani, F | 1 |
| Keegan, MB; Madden, D; McDonald, DG; McMenamin, JB; Najam, Y; Whooley, M | 1 |
| Bernard, DR; Borrey, DC; Engelrelst, VI; Godderis, KO; Langlois, MR | 1 |
| Price, MJ; Remak, E; Selai, CE; Trimble, MR | 1 |
| Filip, M; Frankowska, M; Gołda, A; Przegaliński, E; Vetulani, J; Zaniewska, M | 2 |
| Bonin, RP; Cheng, VY; Chiu, MW; MacDonald, JF; Newell, JG; Orser, BA | 1 |
| Johannessen, SI; Tomson, T | 1 |
| Assis, MA; Fonteles, MM; Freitas, RL; Freitas, RM; Pereira, MB; Silva, RF; Takahashi, RN | 1 |
| Appleton, RE; Macleod, S | 1 |
| Hwang, H; Kim, KJ | 1 |
| Czuczwar, SJ; Luszczki, JJ; Patsalos, PN; Ratnaraj, N | 1 |
| Arenz, N; Kirch, W; Oertel, R; Pietsch, J | 1 |
| Andres-Mach, MM; Czuczwar, SJ; Dudra-Jastrzebska, M; Luszczki, JJ; Patsalos, PN; Ratnaraj, N; Sielski, M | 1 |
| Ali, F; Cavanna, AE; McCorry, D; Rickards, HE | 1 |
| Amore, M; Mandrioli, R; Mercolini, L; Raggi, MA | 1 |
| Filip, D; Florek-Luszczki, M; Luszczki, JJ | 1 |
| Czuczwar, SJ; Luszczki, JJ; Nieoczym, D; Socała, K; Wlaź, P | 1 |
| Heinzlef, O; Monteil-Roch, I | 1 |
| Chahbouni, A; den Burger, JC; Sinjewel, A; Swart, EL; Veldkamp, AI; Vos, RM; Wilhelm, AJ | 1 |
| Martinc, B; Vovk, T | 1 |
| Dotsikas, Y; Kostić, N; Malenović, A; Medenica, M | 1 |
| Grabnar, I; Martinc, B; Roškar, R; Vovk, T | 1 |
| Kumar, A; Niraj, RR; Piplani, S; Pushp, A; Saini, V | 1 |
| Bursová, M; Čabala, R; Coufal, P; Hložek, T | 1 |
| Androsova, G; Auce, P; Avbersek, A; Becker, F; Berghuis, B; Borghei, M; Campbell, E; Cavalleri, GL; Coppola, A; Craig, J; Delanty, N; Depondt, C; Francis, B; Koeleman, BPC; Krause, R; Kunz, WS; Lerche, H; Marson, AG; Sander, JW; Sills, GJ; Sisodiya, SM; Striano, P; Wassenaar, M; Wolking, S; Zara, F | 1 |
| Bar-Klein, G; Friedman, A; Hameed, MQ; Jozwiak, S; Kaminski, RM; Klein, P; Klitgaard, H; Koepp, M; Löscher, W; Prince, DA; Rotenberg, A; Twyman, R; Vezzani, A; Wong, M | 1 |
| Bialer, M; Franco, V; Odi, R; Perucca, E | 1 |
| Alizadeh-Sani, M; Foroumadi, A; Hasanvand, Z; Jouyban, A; Mohammadian, E; Rahimpour, E | 1 |
| Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T | 1 |
| Du, Y; Jin, P; Tang, DQ; You, YX; Zhao, LL; Zhao, YL; Zheng, XX | 1 |
| Chong, E; Kim, DJ; Kim, SM; Lee, SY; Oh, H | 1 |
69 review(s) available for gabapentin and vigabatrin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Antiepileptic medications in development.
Topics: Acetates; Amines; Aminocaproates; Animals; Anticonvulsants; Chemistry, Pharmaceutical; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Drugs, Investigational; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1991 |
[Current viewpoints in the treatment of epilepsies: role of new antiepileptics?].
Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Tolerance; Enzyme Inhibitors; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin | 1995 |
[New antiepileptic medications].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin; Zonisamide | 1995 |
Adjunctive therapy in epilepsy: a cost-effectiveness comparison of alternative treatment options.
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Decision Support Techniques; Drug Therapy, Combination; Drug Tolerance; Electroencephalography; Epilepsy; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Long-Term Care; Triazines; Vigabatrin | 1995 |
New antiepileptic drugs--an explosion of activity.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Approval; Drug Interactions; Drug Therapy, Combination; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Product Surveillance, Postmarketing; Treatment Outcome; Triazines; Vigabatrin | 1995 |
New antiepileptic drugs for children: felbamate, gabapentin, lamotrigine, and vigabatrin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsies, Partial; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; United States; United States Food and Drug Administration; Vigabatrin | 1994 |
Mechanisms of action of new antiepileptic drugs: rational design and serendipitous findings.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1994 |
Newer antiepileptic drugs. Towards an improved risk-benefit ratio.
Topics: Acetamides; Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Piracetam; Propylene Glycols; Risk Factors; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 1994 |
New anti-epileptic drugs in the 1990s.
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Cyclohexanecarboxylic Acids; Drugs, Investigational; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1994 |
Antiepileptic drugs in development: prospects for the near future.
Topics: Acetates; Adult; Amines; Aminocaproates; Animals; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Approval; Drug Design; Drugs, Investigational; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin; Zonisamide | 1994 |
New antiepileptic drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Triazines; Vigabatrin | 1994 |
Advances in pharmacotherapy: recent developments in the treatment of epilepsy.
Topics: Acetates; Amines; Aminocaproates; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1993 |
Antiepileptic drugs in clinical development.
Topics: Acetates; Amines; Aminocaproates; Anticonvulsants; Brain; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Structure-Activity Relationship; Synaptic Transmission; Tiagabine; Topiramate; Triazines; Vigabatrin | 1993 |
Comparative pharmacokinetics of the newer antiepileptic drugs.
Topics: Acetamides; Acetates; Amines; Aminocaproates; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Felbamate; Flunarizine; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1993 |
Pharmacokinetic profile of topiramate in comparison with other new antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin | 1996 |
Utilization of new antiepileptic drugs in children.
Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1996 |
[Advances in the diagnostic and treatment of infantile epilepsy].
Topics: Acetates; Amines; Anticonvulsants; Brain; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Electroencephalography; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Magnetic Resonance Imaging; Phenylcarbamates; Propylene Glycols; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Triazines; Vigabatrin | 1996 |
[Current anti-epilepsy drugs].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1995 |
Antiepileptic drug mechanisms of action.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Calcium Channels; Carbamazepine; Central Nervous System; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Phenytoin; Rats; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium Channels; Triazines; Trimethadione; Valproic Acid; Vigabatrin | 1995 |
Clinical pharmacokinetics of newer antiepileptic drugs. Lamotrigine, vigabatrin, gabapentin and oxcarbazepine.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Tissue Distribution; Triazines; Vigabatrin | 1996 |
A cost minimization study comparing vigabatrin, lamotrigine and gabapentin for the treatment of intractable partial epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cost Control; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Vigabatrin | 1996 |
Important pharmacokinetic properties of antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Biopharmaceutics; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Intestinal Absorption; Lamotrigine; Oxcarbazepine; Topiramate; Triazines; Vigabatrin | 1995 |
Seizure control: how to use the new antiepileptic drugs in older patients.
Topics: Acetates; Age Factors; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Patient Selection; Seizures; Triazines; Vigabatrin | 1996 |
New antiepileptic drugs. II. Clinical use.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Felbamate; Forecasting; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin; Zonisamide | 1996 |
New antiepileptic drugs: a systematic review of their efficacy and tolerability.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cross-Over Studies; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Male; Middle Aged; Nipecotic Acids; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide | 1996 |
Update on the mechanism of action of antiepileptic drugs.
Topics: 4-Aminobutyrate Transaminase; Acetamides; Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Membrane Potentials; Mice; Neurotransmitter Agents; Nipecotic Acids; Phenethylamines; Phenylcarbamates; Propylene Glycols; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tiagabine; Topiramate; Triazines; Vigabatrin | 1996 |
Pharmacokinetics of new antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Carbamazepine; Cyclohexanecarboxylic Acids; Enzyme Induction; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1996 |
The role of the old and the new antiepileptic drugs in special populations: mental and multiple handicaps.
Topics: Acetates; Amines; Anticonvulsants; Cerebral Palsy; Cyclohexanecarboxylic Acids; Disabled Persons; Drug Administration Schedule; Drug Interactions; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Phenylcarbamates; Polypharmacy; Propylene Glycols; Vigabatrin | 1996 |
[Advantages and disadvantages of new antiepileptic drugs].
Topics: Acetates; Adrenocorticotropic Hormone; Amines; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Valproic Acid; Vigabatrin | 1996 |
[Treatment of the epilepsy: new drugs].
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin; Zonisamide | 1996 |
The new antiepileptic drugs.
Topics: Abnormalities, Drug-Induced; Acetates; Adolescent; Adult; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Pregnancy; Propylene Glycols; Randomized Controlled Trials as Topic; Triazines; Vigabatrin | 1996 |
New antiepileptic drugs.
Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin | 1996 |
New antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1996 |
Pharmacokinetics and interaction profile of topiramate: review and comparison with other newer antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Topiramate; Triazines; Vigabatrin | 1997 |
Overview of the safety of newer antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1997 |
[New antiepileptic drugs].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenylcarbamates; Propylene Glycols; Vigabatrin | 1997 |
Pharmacologic and dietary therapies in epilepsy: conventional treatments and recent advances.
Topics: Acetates; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketone Bodies; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Triazines; Valproic Acid; Vigabatrin | 1997 |
Recent advancements in epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Neurosurgery; Phenylcarbamates; Phenytoin; Pia Mater; Propylene Glycols; Temporal Lobe; Topiramate; Triazines; Vigabatrin | 1997 |
Overview of lamotrigine and the new antiepileptic drugs: the challenge.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Exanthema; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Treatment Outcome; Triazines; Valproic Acid; Vigabatrin | 1997 |
Advances in the medical treatment of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diazepam; Drug Approval; Drug Design; Drug Interactions; Drug Resistance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Ketones; Lamotrigine; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Phenylcarbamates; Phenytoin; Prodrugs; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Valproic Acid; Vigabatrin | 1998 |
Measuring human brain GABA in vivo: effects of GABA-transaminase inhibition with vigabatrin.
Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Anticonvulsants; Brain; Brain Chemistry; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Neurological; Vigabatrin | 1998 |
The new antiepileptic drugs: a systematic review of their efficacy and tolerability.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Male; Middle Aged; Randomized Controlled Trials as Topic; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide | 1997 |
Aggravation of focal epileptic seizures by antiepileptic drugs.
Topics: Acetates; Acute Disease; Adult; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Epilepsies, Partial; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenylcarbamates; Propylene Glycols; Vigabatrin | 1998 |
A mechanistic approach to antiepileptic drug interactions.
Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 1998 |
New antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Vigabatrin | 1998 |
Fortnightly review: drug treatment of epilepsy.
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Clobazam; Clonazepam; Cyclohexanecarboxylic Acids; Diethylcarbamazine; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Topiramate; Valproic Acid; Vigabatrin | 1999 |
New antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Practice Guidelines as Topic; Topiramate; Triazines; Vigabatrin | 1999 |
New antiepileptic drugs: comparison of key clinical trials.
Topics: Acetates; Amines; Anticonvulsants; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Placebos; Research Design; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin | 1999 |
Options after the first antiepileptic drug has failed.
Topics: Acetates; Amines; Anticonvulsants; Attitude to Health; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Quality of Life; Treatment Failure; Treatment Outcome; Valproic Acid; Vigabatrin | 1999 |
Monostars: an aid to choosing an antiepileptic drug as monotherapy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Practice Patterns, Physicians'; Triazines; Valproic Acid; Vigabatrin | 1999 |
Use of new antiepileptic drugs in the treatment of childhood epilepsy.
Topics: Acetates; Adult; Age Factors; Amines; Anticonvulsants; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Spasms, Infantile; Tiagabine; Topiramate; Triazines; Vigabatrin | 1999 |
Managing pediatric epilepsy syndromes with new antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1999 |
[GABA-ergic system and antiepileptic drugs].
Topics: Acetates; Amines; Anticonvulsants; Binding, Competitive; Calcium Channels; Chloride Channels; Cyclohexanecarboxylic Acids; Epilepsy; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Humans; Nipecotic Acids; Receptors, GABA; Sodium Channels; Tiagabine; Vigabatrin | 2000 |
New antiepileptic drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2000 |
Therapeutic safety monitoring: what to look for and when to look for it.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2000 |
[Adverse effects of antiepileptic agents].
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Clobazam; Cyclohexanecarboxylic Acids; Drug Utilization; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Norway; Piracetam; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2000 |
New antiepileptic drug therapies.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Phenytoin; Piracetam; Propylene Glycols; Thiazines; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2002 |
The ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come?
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2003 |
Anticonvulsant drugs in primary headaches prophylaxis.
Topics: Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Oxcarbazepine; Piracetam; Topiramate; Triazines; Valproic Acid; Vigabatrin; Zonisamide | 2004 |
Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed?
Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Pregabalin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2006 |
The new antiepileptic drugs.
Topics: Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsies, Partial; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Oxcarbazepine; Piracetam; Pregabalin; Topiramate; Triazines; Vigabatrin; Zonisamide | 2007 |
New pharmacotherapies for pediatric seizures.
Topics: Adolescent; Amines; Animals; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Pediatrics; Piracetam; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide | 2004 |
Behavioral and cognitive effects of anti-epileptic drugs.
Topics: Amines; Anticonvulsants; Antidepressive Agents; Behavior; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Lamotrigine; Neurotransmitter Agents; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Triazines; Vigabatrin | 2010 |
[Pharmacological treatment of spasticity in multiple sclerosis].
Topics: Algorithms; Amines; Baclofen; Botulinum Toxins, Type A; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Double-Blind Method; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusion Pumps, Implantable; Injections, Spinal; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Nerve Block; Neuromuscular Agents; Randomized Controlled Trials as Topic; Spasm; Vigabatrin | 2012 |
Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?
Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Atorvastatin; Brain Injuries, Traumatic; Ceftriaxone; Dibenzazepines; Drug Repositioning; Epilepsy; Epilepsy, Post-Traumatic; Erythropoietin; Fingolimod Hydrochloride; GABA Agents; Gabapentin; Humans; Immunologic Factors; Inflammation; Interleukin 1 Receptor Antagonist Protein; Isoflurane; Levetiracetam; Losartan; Neuroprotective Agents; Oxidative Stress; Pregabalin; Pyrrolidinones; Sirolimus; Stroke; Topiramate; Translational Research, Biomedical; Vigabatrin | 2020 |
Bioequivalence and switchability of generic antiseizure medications (ASMs): A re-appraisal based on analysis of generic ASM products approved in Europe.
Topics: Anticonvulsants; Area Under Curve; Biological Variation, Individual; Dibenzazepines; Drug Substitution; Drugs, Generic; Europe; Gabapentin; Humans; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Pregabalin; Therapeutic Equivalency; Topiramate; Vigabatrin; Zonisamide | 2021 |
Derivatization of γ-Amino Butyric Acid Analogues for Their Determination in the Biological Samples and Pharmaceutical Preparations: A Comprehensive Review.
Topics: Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Pharmaceutical Preparations; Pregabalin; Vigabatrin | 2022 |
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide | 2022 |
6 trial(s) available for gabapentin and vigabatrin
| Article | Year |
|---|---|
Pharmacological control of facilitatory I-wave interaction in the human motor cortex. A paired transcranial magnetic stimulation study.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Central Nervous System Depressants; Cyclohexanecarboxylic Acids; Electric Stimulation; Ethanol; Evoked Potentials, Motor; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lorazepam; Male; Motor Cortex; Neural Inhibition; Phenobarbital; Transcranial Magnetic Stimulation; Triazines; Vigabatrin | 1998 |
Adjunctive therapy in epilepsy with new antiepileptic drugs: is it of any value?
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Clobazam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Humans; Lamotrigine; Male; Patient Compliance; Patient Satisfaction; Prospective Studies; Quality of Life; Triazines; Vigabatrin | 1998 |
[Visual field defects due to antiepileptic drugs].
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Vigabatrin; Vision Disorders; Visual Field Tests; Visual Fields | 1999 |
Gabapentin versus vigabatrin as first add-on for patients with partial seizures that failed to respond to monotherapy: a randomized, double-blind, dose titration study. GREAT Study Investigators Group. Gabapentin in Refractory Epilepsy Add-on Treatment.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Research Design; Retrospective Studies; Treatment Outcome; Vigabatrin | 2000 |
Gabapentin but not vigabatrin is effective in the treatment of acquired nystagmus in multiple sclerosis: How valid is the GABAergic hypothesis?
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Electrooculography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Nystagmus, Physiologic; Vigabatrin; Visual Acuity | 2001 |
Serum concentrations and effects of gabapentin and vigabatrin: observations from a dose titration study.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Monitoring; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Vigabatrin | 2003 |
69 other study(ies) available for gabapentin and vigabatrin
| Article | Year |
|---|---|
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Mechanisms of action of new antiepileptic drugs.
Topics: Acetamides; Acetates; Amines; Aminocaproates; Aminopyridines; Anti-Anxiety Agents; Anticonvulsants; Aspartic Acid; Benzodiazepines; Benzodiazepinones; Clobazam; Cyclohexanecarboxylic Acids; Dibenzocycloheptenes; Dizocilpine Maleate; Epilepsy; Felbamate; Flumazenil; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Imidazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Receptors, GABA-A; Triazines; Vigabatrin | 1989 |
The role of newer anticonvulsants in the management of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Australia; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Vigabatrin | 1995 |
New antiepileptic medications.
Topics: 4-Aminobutyrate Transaminase; Acetamides; Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Tiagabine; Triazines; Vigabatrin | 1995 |
Novel antiepileptic drugs: nursing implications.
Topics: Acetates; Amines; Aminocaproates; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Approval; Drug Interactions; Drug Monitoring; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Patient Care Planning; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1993 |
Costing of antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Argentina; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Costs; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin | 1996 |
[Current role of novel antiepileptics in the treatment of epilepsies].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Resistance; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin | 1996 |
[New medical treatment of epilepsy].
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Costs; Epilepsy; France; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Middle Aged; Triazines; Vigabatrin | 1996 |
An audit of the new antiepileptic drugs in clinical neurological practice.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Treatment Outcome; Triazines; Vigabatrin | 1996 |
Effects of antiepileptic drugs on motor cortex excitability in humans: a transcranial magnetic stimulation study.
Topics: 4-Aminobutyrate Transaminase; Acetates; Adult; Amines; Anticonvulsants; Baclofen; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Differential Threshold; Enzyme Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Motor Cortex; Physical Stimulation; Transcranial Magnetic Stimulation; Vigabatrin | 1996 |
If comparisons can be odious, so can assumptions.
Topics: Acetates; Amines; Anticonvulsants; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Quality of Life; Treatment Outcome; Triazines; Vigabatrin | 1996 |
Utility of the lethargic (lh/lh) mouse model of absence seizures in predicting the effects of lamotrigine, vigabatrin, tiagabine, gabapentin, and topiramate against human absence seizures.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Absence; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Mice; Nipecotic Acids; Tiagabine; Topiramate; Triazines; Vigabatrin | 1997 |
A naturalistic study of the use of vigabatrin, lamotrigine and gabapentin in adults with learning disabilities.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Comorbidity; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Lamotrigine; Learning Disabilities; Male; Middle Aged; Retrospective Studies; Seizures; Social Behavior Disorders; Substance-Related Disorders; Treatment Outcome; Triazines; Vigabatrin | 1997 |
Comparison of the preclinical anticonvulsant profiles of tiagabine, lamotrigine, gabapentin and vigabatrin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Lamotrigine; Male; Mice; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Tiagabine; Triazines; Vigabatrin | 1997 |
Sensitive high-performance liquid chromatographic method with fluorometric detection for the simultaneous determination of gabapentin and vigabatrin in serum and urine.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Sensitivity and Specificity; Spectrometry, Fluorescence; Vigabatrin | 1998 |
Gabapentin add-on therapy with adaptable dosages in 610 patients with partial epilepsy: an open, observational study. The French Gabapentin Collaborative Group.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome; Vigabatrin | 1998 |
Gabapentin potentiation of the antiepileptic efficacy of vigabatrin in an in vitro model of epilepsy.
Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Animals; Anticonvulsants; Bicuculline; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Epilepsy; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium Deficiency; Polypharmacy; Seizures; Vigabatrin | 1998 |
A high-performance liquid chromatography micromethod for the simultaneous determination of vigabatrin and gabapentin in serum.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Microchemistry; Sensitivity and Specificity; Vigabatrin | 1998 |
The outcome of prescribing novel anticonvulsants in an outpatient setting: factors affecting response to medication.
Topics: Acetates; Adolescent; Adult; Ambulatory Care; Amines; Anticonvulsants; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Drug Prescriptions; Epilepsy; Female; Follow-Up Studies; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Patient Compliance; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Wales | 1998 |
The management of epilepsy in a hospital for people with a learning disability.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Utilization; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Hospitals, Psychiatric; Humans; Lamotrigine; Learning Disabilities; Male; Middle Aged; Phenobarbital; Triazines; United Kingdom; Vigabatrin | 1999 |
Inhibition of uptake, steady-state currents, and transient charge movements generated by the neuronal GABA transporter by various anticonvulsant drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Binding Sites; Biological Transport; Carrier Proteins; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Conductivity; Female; GABA Plasma Membrane Transport Proteins; Gabapentin; gamma-Aminobutyric Acid; Kinetics; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Mice; Nipecotic Acids; Oocytes; Organic Anion Transporters; Patch-Clamp Techniques; Tiagabine; Valproic Acid; Vigabatrin; Xenopus laevis | 1999 |
The long-term use of gabapentin, lamotrigine, and vigabatrin in patients with chronic epilepsy.
Topics: Acetates; Ambulatory Care; Amines; Anticonvulsants; Chronic Disease; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Longitudinal Studies; Medical Records; Multicenter Studies as Topic; Patient Dropouts; Pharmacoepidemiology; Proportional Hazards Models; Retrospective Studies; Survival Analysis; Treatment Outcome; Triazines; United Kingdom; Vigabatrin | 1999 |
Refractory epilepsy: treatment with new antiepileptic drugs.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Nipecotic Acids; Patient Dropouts; Retrospective Studies; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin | 2000 |
A comparison of four new antiepileptic medications.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Medical Records; Middle Aged; Retrospective Studies; Survival Analysis; Topiramate; Treatment Outcome; Triazines; Vigabatrin | 2000 |
Effect of vigabatrin and gabapentin on phenytoin pharmacokinetics in the dog.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dogs; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Male; Phenytoin; Vigabatrin | 2000 |
Different effects of GABAergic anticonvulsants on 4-aminopyridine-induced spontaneous GABAergic hyperpolarizations of hippocampal pyramidal cells--implication for their potency in migraine therapy.
Topics: 4-Aminopyridine; Acetates; Amines; Analgesics; Animals; Anticonvulsants; Convulsants; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Humans; Membrane Potentials; Migraine Disorders; Nipecotic Acids; Pyramidal Cells; Tiagabine; Time Factors; Valproic Acid; Vigabatrin | 2000 |
Fast isocratic high-performance liquid chromatographic assay method for the simultaneous determination of gabapentin and vigabatrin in human serum.
Topics: Acetates; Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Vigabatrin | 2000 |
[Clinical utilization of new anti-epileptic agents].
Topics: Acetates; Amines; Anemia, Aplastic; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Visual Fields | 2000 |
Adverse event monitoring in lamotrigine patients: a pharmacoepidemiologic study in the United Kingdom.
Topics: Acetates; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Death, Sudden; Drug Eruptions; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Lamotrigine; Male; Middle Aged; Neurotoxicity Syndromes; Pharmacoepidemiology; Product Surveillance, Postmarketing; Triazines; United Kingdom; Vigabatrin | 2001 |
Determination of the antiepileptics vigabatrin and gabapentin in dosage forms and biological fluids using Hantzsch reaction.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fluorescent Dyes; Gabapentin; gamma-Aminobutyric Acid; Humans; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tablets; Vigabatrin | 2001 |
Effects of antiepileptic drugs on cognition.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; Triazoles; Vigabatrin | 2001 |
Management strategies for refractory localization-related seizures.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Practice Patterns, Physicians'; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin | 2001 |
Spectrofluorimetric determination of vigabatrin and gabapentin in urine and dosage forms through derivatization with fluorescamine.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dosage Forms; Fluorescamine; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Molecular Structure; Reproducibility of Results; Spectrometry, Fluorescence; Vigabatrin | 2002 |
Pregnancy registries in epilepsy.
Topics: Abnormalities, Drug-Induced; Acetates; Amines; Anticonvulsants; Australia; Cross-Cultural Comparison; Cyclohexanecarboxylic Acids; Data Collection; Databases as Topic; Epilepsy; Europe; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; India; Infant, Newborn; International Cooperation; Lamotrigine; Pregnancy; Pregnancy Complications; Product Surveillance, Postmarketing; Registries; Severity of Illness Index; Triazines; United Kingdom; Vigabatrin | 2001 |
Gabapentin and vigabatrin increase GABA in the human neocortical slice.
Topics: Acetates; Adolescent; Adult; Amines; Animals; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Male; Middle Aged; Neocortex; Rats; Rats, Sprague-Dawley; Vigabatrin | 2002 |
The 'number needed to treat' with levetiracetam (LEV): comparison with the other new antiepileptic drugs (AEDs).
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2002 |
Modulation of the in vivo effects of gabapentin by vigabatrin and SKF89976A.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dentate Gyrus; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Male; Neural Inhibition; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Reaction Time; Vigabatrin | 2002 |
Simultaneous isocratic HPLC determination of vigabatrin and gabapentin in human plasma by dansyl derivatization.
Topics: Acetates; Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dansyl Compounds; Gabapentin; gamma-Aminobutyric Acid; Humans; Vigabatrin | 2003 |
Acute effects of gabapentin and pregabalin on rat forebrain cellular GABA, glutamate, and glutamine concentrations.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Injections, Intraperitoneal; Magnetic Resonance Spectroscopy; Male; Neurons; Pregabalin; Prosencephalon; Rats; Rats, Long-Evans; Vigabatrin | 2003 |
Vigabatrin, but not gabapentin or topiramate, produces concentration-related effects on enzymes and intermediates of the GABA shunt in rat brain and retina.
Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Fructose; Gabapentin; gamma-Aminobutyric Acid; Male; Rats; Rats, Sprague-Dawley; Retina; Topiramate; Vigabatrin; Visual Fields | 2003 |
Interaction between anticonvulsants and human placental carnitine transporter.
Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techniques; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Models, Biological; Nipecotic Acids; Organic Cation Transport Proteins; Phenytoin; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Proteins; Solute Carrier Family 22 Member 5; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2004 |
The effect of Vigabatrin, Lamotrigine and Gabapentin on the fertility, weights, sex hormones and biochemical profiles of male rats.
Topics: Amines; Analgesics; Animals; Antimanic Agents; Body Weight; Cyclohexanecarboxylic Acids; Female; Fertility; Follicle Stimulating Hormone; Gabapentin; gamma-Aminobutyric Acid; Lamotrigine; Male; Organ Size; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Testosterone; Triazines; Vigabatrin | 2004 |
Simultaneous high-performance liquid chromatographic analysis of pregabalin, gabapentin and vigabatrin in human serum by precolumn derivatization with o-phtaldialdehyde and fluorescence detection.
Topics: Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Gabapentin; gamma-Aminobutyric Acid; Humans; Indicators and Reagents; o-Phthalaldehyde; Pregabalin; Reference Standards; Reproducibility of Results; Solutions; Specimen Handling; Spectrometry, Fluorescence; Vigabatrin | 2004 |
The use of lamotrigine, vigabatrin and gabapentin as add-on therapy in intractable epilepsy of childhood.
Topics: Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Tolerance; Epilepsies, Partial; Epilepsy, Generalized; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Infant, Newborn; Lamotrigine; Male; Retrospective Studies; Triazines; Vigabatrin | 2005 |
Quantitative determination of vigabatrin and gabapentin in human serum by gas chromatography-mass spectrometry.
Topics: Amines; Calibration; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Sensitivity and Specificity; Vigabatrin | 2005 |
Evaluation of health status in epilepsy using the EQ-5D questionnaire: a prospective, observational, 6-month study of adjunctive therapy with anti-epileptic drugs.
Topics: Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Prospective Studies; Secondary Prevention; Sickness Impact Profile; Surveys and Questionnaires; Topiramate; Triazines; Vigabatrin | 2005 |
Various GABA-mimetic drugs differently affect cocaine-evoked hyperlocomotion and sensitization.
Topics: Amines; Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agents; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Male; Motor Activity; Nipecotic Acids; Rats; Rats, Wistar; Tiagabine; Vigabatrin | 2006 |
Gabapentin increases a tonic inhibitory conductance in hippocampal pyramidal neurons.
Topics: 4-Aminobutyrate Transaminase; Amines; Analgesics; Animals; Blotting, Western; Cyclohexanecarboxylic Acids; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Mice; Neural Conduction; Patch-Clamp Techniques; Pregnancy; Pyramidal Cells; Receptors, GABA-A; Receptors, GABA-B; Somatosensory Cortex; Synapses; Vigabatrin | 2006 |
Diverse effects of GABA-mimetic drugs on cocaine-evoked self-administration and discriminative stimulus effects in rats.
Topics: Amines; Animals; Behavior, Animal; Cocaine; Cyclohexanecarboxylic Acids; Discrimination Learning; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Nipecotic Acids; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Tiagabine; Vigabatrin | 2007 |
Study pharmacologic of the GABAergic and glutamatergic drugs on seizures and status epilepticus induced by pilocarpine in adult Wistar rats.
Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Ketamine; Male; Muscarinic Agonists; N-Methylaspartate; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Receptors, GABA; Receptors, Neurotransmitter; Seizures; Status Epilepticus; Vigabatrin | 2007 |
New antiepileptic drugs in pediatric epilepsy.
Topics: Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Pediatrics; Phenylcarbamates; Piracetam; Practice Guidelines as Topic; Propylene Glycols; Topiramate; Triazines; Vigabatrin | 2008 |
Isobolographic and behavioral characterizations of interactions between vigabatrin and gabapentin in two experimental models of epilepsy.
Topics: Amines; Animals; Anticonvulsants; Behavior, Animal; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Muscle Strength; Pentylenetetrazole; Psychomotor Performance; Seizures; Vigabatrin | 2008 |
Simultaneous determination of three anticonvulsants using hydrophilic interaction LC-MS.
Topics: Amines; Anticonvulsants; Calibration; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Pregabalin; Solutions; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Temperature; Vigabatrin; Water | 2009 |
Pharmacodynamic and pharmacokinetic interaction profiles of levetiracetam in combination with gabapentin, tiagabine and vigabatrin in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis.
Topics: Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Interactions; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Levetiracetam; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Piracetam; Seizures; Tiagabine; Tissue Distribution; Vigabatrin | 2009 |
Simultaneous HPLC-F analysis of three recent antiepileptic drugs in human plasma.
Topics: Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dansyl Compounds; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Spectrometry, Fluorescence; Topiramate; Vigabatrin | 2010 |
Interactions of pregabalin with gabapentin, levetiracetam, tiagabine and vigabatrin in the mouse maximal electroshock-induced seizure model: a type II isobolographic analysis.
Topics: Amines; Animals; Anticonvulsants; Avoidance Learning; Confidence Intervals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Levetiracetam; Male; Mice; Motor Activity; Piracetam; Pregabalin; Seizures; Vigabatrin | 2012 |
Sildenafil influences the anticonvulsant activity of vigabatrin and gabapentin in the timed pentylenetetrazole infusion test in mice.
Topics: Amines; Animals; Anticonvulsants; Avoidance Learning; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Male; Mice; Motor Skills; Pentylenetetrazole; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Seizures; Sildenafil Citrate; Sulfones; Vigabatrin | 2012 |
Rapid quantification of gabapentin, pregabalin, and vigabatrin in human serum by ultraperformance liquid chromatography with mass-spectrometric detection.
Topics: Amines; Anticonvulsants; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Tandem Mass Spectrometry; Vigabatrin | 2013 |
A simple high-throughput method for determination of antiepileptic analogues of γ-aminobutyric acid in pharmaceutical dosage forms using microplate fluorescence reader.
Topics: Amines; Anticonvulsants; Capsules; Cyclohexanecarboxylic Acids; Fluorescamine; Gabapentin; gamma-Aminobutyric Acid; High-Throughput Screening Assays; Pharmaceutical Preparations; Pregabalin; Spectrometry, Fluorescence; Tablets; Temperature; Vigabatrin | 2013 |
Effects of derivatization reagents consisting of n-alkyl chloroformate/n-alcohol combinations in LC-ESI-MS/MS analysis of zwitterionic antiepileptic drugs.
Topics: 1-Propanol; Amines; Anticonvulsants; Butanols; Cyclohexanecarboxylic Acids; Esters; Ethanol; Formates; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Methanol; Pregabalin; Solutions; Spectrometry, Mass, Electrospray Ionization; Vigabatrin | 2013 |
Simultaneous determination of gabapentin, pregabalin, vigabatrin, and topiramate in plasma by HPLC with fluorescence detection.
Topics: Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Fluorescence; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Pregabalin; Solid Phase Extraction; Topiramate; Vigabatrin | 2014 |
Homology modelling and molecular docking studies of human placental cadherin protein for its role in teratogenic effects of anti-epileptic drugs.
Topics: Acetamides; Amines; Animals; Anticonvulsants; Binding Sites; Cadherins; Calcium; Cations, Divalent; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Pregabalin; Pregnancy; Sequence Homology; Teratogens; Vigabatrin | 2016 |
Gabapentin, Pregabalin and Vigabatrin Quantification in Human Serum by GC-MS After Hexyl Chloroformate Derivatization.
Topics: Amines; Anticonvulsants; Calibration; Computer-Aided Design; Cyclohexanecarboxylic Acids; Formates; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Pregabalin; Vigabatrin | 2016 |
Comparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Ataxia; Benzodiazepines; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Databases, Factual; Diplopia; Dizziness; Epilepsy, Temporal Lobe; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Humans; Lamotrigine; Lethargy; Male; Middle Aged; Oxcarbazepine; Pregabalin; Retrospective Studies; Sclerosis; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Vertigo; Vigabatrin; Vision Disorders; Young Adult | 2017 |
A simple and easy non-derivatization gas chromatography-mass spectrometry method for simultaneous quantification of valproic acid, gabapentin, pregabalin, and vigabatrin in human plasma.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Pregabalin; Valproic Acid; Vigabatrin | 2023 |
Quantification of Gabapentin, Lacosamide, Perampanel, Pregabalin, Rufinamide, and Vigabatrin in Serum Using Liquid Chromatography-Tandem Mass Spectrometry.
Topics: Anticonvulsants; Chromatography, Liquid; Gabapentin; Lacosamide; Pregabalin; Tandem Mass Spectrometry; Vigabatrin | 2024 |