Compounds > gabapentin

gabapentin and substance p

gabapentin has been researched along with substance p in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Chaplan, SR; Partridge, BJ; Sakamoto, E; Yaksh, TL1
Hughes, J; Maneuf, YP; McKnight, AT1
Fehrenbacher, JC; Taylor, CP; Vasko, MR1
Dickenson, AH; Hunt, SP; Rahman, W; Rygh, LJ; Suzuki, R; Webber, M1
Ahn, ES; Han, DW; Hong, YW; Kim, H; Lee, JH; Min, KT; Park, S1
Takasusuki, T; Yaksh, TL1
Inada, E; Iseki, M; Kumakura, S; Nagaoka, I; Someya, A; Yamaguchi, K1
Chen, R; Chen, Z; Dong, J; Huang, J; Ji, X; Xu, Y; Yan, W; Zhan, C; Zheng, Z; Zhi, H; Zhong, M1
Diwakarla, S; Fransson, R; Gaugaz, FZ; Hallberg, M; Jonsson, A; Karlgren, M; Lesniak, A; Nyberg, F; Sandström, A; Skogh, A; Sköld, C; Svensson, R1

Other Studies

9 other study(ies) available for gabapentin and substance p

ArticleYear
Characterization of the effects of gabapentin and 3-isobutyl-gamma-aminobutyric acid on substance P-induced thermal hyperalgesia.
    Anesthesiology, 1998, Volume: 88, Issue:1

    Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Glutamate; Serine; Stereoisomerism; Substance P

1998
Gabapentin inhibits the substance P-facilitated K(+)-evoked release of [(3)H]glutamate from rat caudial trigeminal nucleus slices.
    Pain, 2001, Volume: 93, Issue:2

    Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neurokinin-1 Receptor Antagonists; Organ Culture Techniques; Piperidines; Potassium; Pregabalin; Rats; Rats, Inbred Strains; Stereoisomerism; Substance P; Trigeminal Nucleus, Spinal; Tritium

2001
Pregabalin and gabapentin reduce release of substance P and CGRP from rat spinal tissues only after inflammation or activation of protein kinase C.
    Pain, 2003, Volume: 105, Issue:1-2

    Topics: Acetates; Amines; Analgesics; Animals; Calcitonin Gene-Related Peptide; Cyclohexanecarboxylic Acids; Enzyme Activation; Foot; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Inflammation; Male; Phorbol 12,13-Dibutyrate; Pregabalin; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P

2003
Spinal-supraspinal serotonergic circuits regulating neuropathic pain and its treatment with gabapentin.
    Pain, 2005, Volume: 117, Issue:3

    Topics: Action Potentials; Amines; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Cell Count; Cell Death; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation; Hot Temperature; Immunohistochemistry; Male; Neurons; Ondansetron; Pain; Pain Measurement; Pain Threshold; Pokeweed Mitogens; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-1; Ribosome Inactivating Proteins, Type 1; Saporins; Serotonin; Serotonin Antagonists; Spinal Cord; Substance P; Time Factors

2005
Pregabalin and gabapentin inhibit substance P-induced NF-kappaB activation in neuroblastoma and glioma cells.
    Journal of cellular biochemistry, 2008, Oct-01, Volume: 105, Issue:2

    Topics: Amines; Animals; Cell Line, Tumor; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Glioma; Humans; Inflammation; Neuroblastoma; NF-kappa B; Pregabalin; Rats; Rats, Sprague-Dawley; Signal Transduction; Substance P

2008
The effects of intrathecal and systemic gabapentin on spinal substance P release.
    Anesthesia and analgesia, 2011, Volume: 112, Issue:4

    Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Injections, Spinal; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P

2011
Anti‑inflammatory actions of gabapentin and pregabalin on the substance P‑induced mitogen‑activated protein kinase activation in U373 MG human glioblastoma astrocytoma cells.
    Molecular medicine reports, 2017, Volume: 16, Issue:5

    Topics: Amines; Anti-Inflammatory Agents; Astrocytoma; Cell Line, Tumor; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glioblastoma; Humans; Interleukin-6; Interleukin-8; MAP Kinase Signaling System; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pregabalin; Receptors, Neurokinin-1; Substance P

2017
Gabapentin alleviated the cough hypersensitivity and neurogenic inflammation in a guinea pig model with repeated intra-esophageal acid perfusion.
    European journal of pharmacology, 2023, Nov-15, Volume: 959

    Topics: Animals; Cough; Gabapentin; Gastroesophageal Reflux; Guinea Pigs; Hydrochloric Acid; Lung; Neurogenic Inflammation; Perfusion; Receptors, Neurokinin-1; Substance P

2023
An imidazole based H-Phe-Phe-NH
    Bioorganic & medicinal chemistry letters, 2018, 08-01, Volume: 28, Issue:14

    Topics: Amides; Animals; Cell Death; Cell Survival; Cells, Cultured; Dipeptides; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Injections, Intraperitoneal; Mice; Molecular Structure; Peptidomimetics; Rats; Spinal Nerves

2018