gabapentin and riluzole

gabapentin has been researched along with riluzole in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (26.32)18.2507
2000's7 (36.84)29.6817
2010's7 (36.84)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Andrus, PK; Cutting, FB; Doble, A; Gurney, ME; Hall, ED; Taylor, CP; Zhai, P1
Miller, RG2
Forshew, DA1
Bernardi, G; Caramia, MD; Desiato, MT; Iani, C; Palmieri, MG; Scalise, A; Telera, S1
Itzhak, Y; Martin, JL1
Armon, C1
Bezprozvanny, I; Tang, T; Wu, J1
Coderre, TJ; Kumar, N; Lefebvre, CD; Yu, JS1
Eisenach, JC; Hayashida, K; Yoshizumi, M1
Fernandez, L; Gurevich, M; Hurst, LC; Komatsu, DE1

Reviews

5 review(s) available for gabapentin and riluzole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Carrell-Krusen Symposium invited lecture. Clinical trials in motor neuron diseases.
    Journal of child neurology, 1999, Volume: 14, Issue:3

    Topics: Acetates; Adolescent; Adult; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain-Derived Neurotrophic Factor; Child; Child, Preschool; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Guidelines as Topic; Humans; Infant; Insulin-Like Growth Factor I; Male; Mice; Middle Aged; Motor Neuron Disease; Muscular Atrophy, Spinal; Nerve Growth Factors; Outcome Assessment, Health Care; Postpoliomyelitis Syndrome; Riluzole

1999
Therapeutic advances: new hope for patients with ALS.
    Nursing spectrum (D.C./Baltimore metro ed.), 1998, Dec-14, Volume: 8, Issue:25

    Topics: Acetates; Aged; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Long-Term Care; Neuroprotective Agents; Patient Education as Topic; Riluzole

1998
How can physicians and their patients with ALS decide to use the newly-available treatments to slow disease progression?
    Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases, 1999, Volume: 1, Issue:1

    Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Disease Progression; Gabapentin; gamma-Aminobutyric Acid; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Neuroprotective Agents; Quality of Life; Riluzole; Sickness Impact Profile

1999
Emerging Strategies on Adjuvant Therapies for Nerve Recovery.
    The Journal of hand surgery, 2018, Volume: 43, Issue:4

    Topics: Absorbable Implants; Allografts; Autografts; Calcium Channel Blockers; Erythropoietin; Gabapentin; Humans; Immunosuppressive Agents; Lithium Compounds; Nerve Regeneration; Neuroprotective Agents; Neurosurgical Procedures; Peripheral Nerve Injuries; Peripheral Nerves; Recovery of Function; Riluzole; Stem Cell Transplantation; Valproic Acid; Veins; Wallerian Degeneration

2018

Trials

1 trial(s) available for gabapentin and riluzole

ArticleYear
Pharmacologic reversal of cortical hyperexcitability in patients with ALS.
    Neurology, 2000, Jan-11, Volume: 54, Issue:1

    Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Cerebral Cortex; Cyclohexanecarboxylic Acids; Diazepam; Drug Therapy, Combination; Evoked Potentials, Motor; Female; GABA Agonists; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetics; Male; Middle Aged; Neural Inhibition; Neuroprotective Agents; Physical Stimulation; Riluzole; Synaptic Transmission; Treatment Outcome

2000

Other Studies

13 other study(ies) available for gabapentin and riluzole

ArticleYear
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis.
    Annals of neurology, 1996, Volume: 39, Issue:2

    Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain; Cyclohexanecarboxylic Acids; Diet; Disease Progression; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Mice, Transgenic; Oxidative Stress; Riluzole; Spinal Cord; Superoxide Dismutase; Survival Analysis; Thiazoles; Vitamin E

1996
New approaches to therapy of amyotrophic lateral sclerosis.
    The Western journal of medicine, 1998, Volume: 168, Issue:4

    Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain-Derived Neurotrophic Factor; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Insulin-Like Growth Factor I; Mice; Riluzole

1998
Effect of riluzole and gabapentin on cocaine- and methamphetamine-induced behavioral sensitization in mice.
    Psychopharmacology, 2000, Volume: 151, Issue:2-3

    Topics: Acetates; Amines; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cyclohexanecarboxylic Acids; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Methamphetamine; Mice; Motor Activity; Riluzole; Time Factors

2000
Evaluation of clinically relevant glutamate pathway inhibitors in in vitro model of Huntington's disease.
    Neuroscience letters, 2006, Oct-30, Volume: 407, Issue:3

    Topics: Amines; Animals; Apoptosis; Cells, Cultured; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Folic Acid; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Huntington Disease; Lamotrigine; Male; Memantine; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Riluzole; Triazines

2006
A comparison of the glutamate release inhibition and anti-allodynic effects of gabapentin, lamotrigine, and riluzole in a model of neuropathic pain.
    Journal of neurochemistry, 2007, Volume: 100, Issue:5

    Topics: Amines; Analgesics; Animals; Anticonvulsants; Cold Temperature; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Hyperalgesia; Lamotrigine; Male; Microdialysis; Pain; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Long-Evans; Riluzole; Spinal Cord; Touch; Triazines

2007
Riluzole and gabapentinoids activate glutamate transporters to facilitate glutamate-induced glutamate release from cultured astrocytes.
    European journal of pharmacology, 2012, Feb-29, Volume: 677, Issue:1-3

    Topics: Amines; Amino Acid Transport System X-AG; Animals; Astrocytes; Biological Transport; Calcium; Cells, Cultured; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Intracellular Space; Ligands; Protein Subunits; Rats; Riluzole; Sodium

2012