gabapentin and pregabalin

gabapentin has been researched along with pregabalin in 508 studies

Research

Studies (508)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (1.57)18.2507
2000's95 (18.70)29.6817
2010's281 (55.31)24.3611
2020's124 (24.41)2.80

Authors

AuthorsStudies
Bo-Hua, Z; He, L; Hong-Ju, Y; Jun-Wei, W; Nan, Z; Wei-Guo, S; Wei-Xiu, Y; Zhe-Hui, G; Zheng-Hua, G; Zhi-Pu, L; Zhong-Wei, J1
Belliotti, TR; Capiris, T; Ekhato, IV; Field, MJ; Heffner, TG; Kinsora, JJ; Meltzer, LT; Schwarz, JB; Taylor, CP; Thorpe, AJ; Vartanian, MG; Weber, ML; Wise, LD; Wustrow, DJ; Zhi-Su, T1
Belliotti, TR; Bryans, JS; Buchholz, L; Capiris, T; Donevan, SD; El-Kattan, A; Field, MJ; Kinsora, JJ; Kneen, CO; Lotarski, SM; Schwarz, JB; Taylor, CP; Thorpe, AJ; Vartanian, MG; Williams, D; Wustrow, DJ1
Blakemore, DC; Bryans, JS; Carnell, P; Chessum, NE; Field, MJ; Kinsella, N; Kinsora, JK; Osborne, SA; Williams, SC1
Blakemore, DC; Bryans, JS; Carnell, P; Field, MJ; Kinsella, N; Kinsora, JK; Meltzer, LT; Osborne, SA; Thompson, LR; Williams, SC1
Hamersak, Z; Horvat, S; Jolas, T; Stipetić, I1
Brugier, D; Harrison, A; Hough, J; Maw, GN; Newman, J; Otterburn, J; Price, J; Rawson, DJ; Thompson, LR; Turnpenny, P; Warren, AN2
Blakemore, DC; Brugier, D; Bryans, JS; Chu, WL; Maw, GN; Poinsard, C; Rawson, DJ; Thompson, LR; Warren, AN1
Abbadie, C; Bugianesi, RM; Chakravarty, PK; Dai, G; Duffy, JL; Garcia, ML; Green, M; Haedo, RJ; Herrington, JB; Jochnowitz, N; Kaczorowski, GJ; Li, X; Lyons, KA; McGowan, E; McManus, OB; Mistry, S; Shao, PP; Smith, MM; Sun, SY; Swensen, AM; Varughese, DJ; Warren, VA; Ye, F1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bigge, C; Hill, DR; Suman-Chauhan, N; Taylor, CP; Vartanian, MG; Yuen, PW1
Field, MJ; Hughes, J; Lewis, AS; McCleary, S; Oles, RJ; Singh, L1
Field, MJ; Holloman, EF; Hughes, J; McCleary, S; Singh, L1
Jun, JH; Yaksh, TL1
Carlton, SM; Zhou, S1
Jones, DL; Sorkin, LS1
Field, MJ; Hughes, J; McCleary, S; Singh, L1
Bockbrader, HN; Fleisher, D; Jezyk, N; Li, C; Stewart, BH; Wu, X1
Borosky, SA; Dooley, DJ; Mieske, CA1
Stringer, JL; Taylor, CP1
Donovan, CM; Dooley, DJ; Pugsley, TA1
Jefferson, JW1
Feuerstein, TJ; Huppertz, HJ; Schulze-Bonhage, A1
Hughes, J; Maneuf, YP; McKnight, AT1
Bockbrader, H; Fleisher, D; Li, C; Liu, G; Piyapolrungroj, N1
Andrews, N; Blake, R; Ferrigan, L; Loomis, S; McKnight, AT; Singh, L1
Clusmann, H; Dooley, DJ; Duffy, S; Fink, K; Göthert, M; Meder, WP; Suman-Chauhan, N1
Donovan, CM; Dooley, DJ; Meder, WP; Whetzel, SZ1
Cui, JG; Linderoth, B; Meyerson, BA; Schechtmann, G; Wallin, J; Yakhnitsa, V1
Chatterjea, D; Hammond, DL; Hurley, RW; Rose Feng, M; Taylor, CP1
Errante, LD; Petroff, OA1
Fehrenbacher, JC; Taylor, CP; Vasko, MR1
Chesler, EJ; Kokayeff, A; Lariviere, WR; Mogil, JS; Ritchie, J; Wilson, SG1
Stahl, SM3
Yatham, LN1
Ilag, VL1
Barkworth, L; Evans, RM; Martin, DJ; McClelland, D; Scott, RH1
Taylor, CP2
Dahl, JB; Mathiesen, O; Møiniche, S1
Cunningham, MO; Dooley, DJ; Jones, RS; Thompson, SE; Woodhall, GL1
Edelbroek, PM; Vermeij, TA1
Ali, H; Boutwell, C; Dubinsky, RM; El-Chami, Z; Kabbani, H1
Boileau, C; Boily, M; Brunet, J; El-Kattan, A; Flory, C; Martel-Pelletier, J; Pelletier, JP; Schrier, D; Tardif, G1
Colbry, NL; Dickerson, MR; Donevan, SD; El-Kattan, A; Gibbons, SE; Graham, SR; Guzzo, PR; Kinsora, JJ; Le, VD; Li, Z; Lotarski, SM; Schwarz, JB; Su, TZ; Taylor, CP; Thorpe, AJ; Vartanian, MG; Weber, ML; Wustrow, DJ1
Maeda, K; Yasuda, H1
Liu, H; Shi, W; Yang, H; Zhang, Y; Zhong, B1
Sills, GJ1
Guay, DR1
Barta, NS; Colbry, NL; DeOrazio, RJ; Dickerson, MR; Donevan, SD; El-Kattan, A; Galatsis, P; Gibbons, SE; Hudack, RA; Kinsora, JJ; Li, Z; Lin, K; Lotarski, SM; Manning, DD; Nichelson, B; Schwarz, JB; Taylor, CP; Thorpe, AJ; Vartanian, MG; Wustrow, DJ; Zhu, Z1
Hasan, A; Lang, N; Paulus, W; Sueske, E; Tergau, F1
Gazulla, J; Tintoré, MA1
Feuerstein, TJ; Stefan, H1
Johannessen, SI; Tomson, T1
Angelotti, T; Fauman, E; Taylor, CP1
Dukes, E; Gordon, A; Rousseau, C; Tarride, JE; Vera-Llonch, M1
Forde, G1
Miura, Y1
Beyreuther, BK; Geis, C; Sommer, C; Stöhr, T1
Jatzko, A; Petroianu, GA; Stegmeier-Petroianu, A1
Golembiewski, JA1
Terneus, W1
Brennan, TJ; Pogatzki-Zahn, EM; Zahn, PK1
Field, MJ; Li, Z; Schwarz, JB1
Gazulla, J; Tintoré, M1
Hamunen, K; Kalso, E; Kontinen, VK; Tiippana, EM1
Klein, S; Nicolas, LB; Prinssen, EP1
Kempler, P; Várkonyi, T1
Goldenberg, DL1
Baglioni, P; Govindan, J; Khan, A1
Holloway, RG; Noyes, K; O'Connor, AB2
Petroianu, G; Stegmeier-Petroianu, A1
Limmroth, V; Puppe, A1
Gilron, I1
Díaz, S; Dukes, E; Rejas, J; Rodríguez, MJ; Vera-Llonch, M1
Cruccu, G1
Gore, M; Sadosky, A; Stacey, B; Tai, KS1
Coquerel, A; de la Gastine, B; Husson, B; Laville, MA; Le Boisselier, R; Mosquet, B1
Galluzzi, KE1
Appleton, RE; Macleod, S1
Brawek, B; Dooley, DJ; Feuerstein, TJ; Löffler, M; Weyerbrock, A1
Derry, S; McQuay, HJ; Moore, RA; Straube, S1
Anselmi, B; De Cesaris, F; Del Bene, E; Fanciullacci, M; Pietrini, U1
Abeles, AM; Abeles, M; Pillinger, MH; Solitar, BM1
Amaniti, E; Kouvelas, D; Papazisis, G; Tzellos, TG1
Ahn, ES; Han, DW; Hong, YW; Kim, H; Lee, JH; Min, KT; Park, S1
Ono, H; Takasu, K; Takeuchi, Y; Tanabe, M1
Dakin, H; Gabriel, A; Hertel, N; Liedgens, H; Mitchell, S; Nautrup, BP; Nuijten, M1
Forde, G; Stanos, S1
Yamamoto, T1
Bannwarth, B1
Boyd, ST; Causey, NW; Mihm, L1
Brawek, B; Feuerstein, TJ; Löffler, M; Weyerbrock, A1
de Medicis, E1
Arenz, N; Kirch, W; Oertel, R; Pietsch, J1
Rouvel-Tallec, A1
Chancellor, J; Garcia-Cebrian, A; Le, TK; Löthgren, M; Monz, B; Quilici, S; Said, G; Simon, D1
Caraci, F; Chiechio, S; Copani, A; Nicoletti, F; Rampello, L; Sabato, AF; Zammataro, M1
Emrich, HM; Sieberer, M1
Honda, M; Ono, H; Ono, K; Tanabe, M1
Bernardy, K; Häuser, W; Sommer, C; Uçeyler, N1
Chaput, A; Evans, H; Kim, C; Tang, R1
Brown, P; Healy, DG; Ingle, GT1
Carpenedo, R; Celidonio, L; Dauri, M; Faria, S; Gatti, A; Sabato, AF1
Peres, MF1
Dworkin, RH; O'Connor, AB1
Kempler, P1
Toth, C1
Greene, SM; Simpson, CB1
Bowrin, K; Choy, E; Lloyd, A; Richards, S; Sadosky, A; Watson, P; Zlateva, G1
Audette, J; Baron, R; Dworkin, RH; Gourlay, GK; Haanpää, ML; Kent, JL; Krane, EJ; Lebel, AA; Levy, RM; Mackey, SC; Mayer, J; Miaskowski, C; O'Connor, AB; Raja, SN; Rice, AS; Schmader, KE; Stacey, B; Stanos, S; Treede, RD; Turk, DC; Walco, GA; Wells, CD1
Bauer, CS; Dickenson, AH; Dolphin, AC; Lujan, R; Rahman, W; Tran-van-Minh, A1
Barrett, JA; Donevan, S; Hedberg, TG; Taylor, CP; Tuchman, M1
Bujoreanu, IS; DeMaso, DR; Ibeziako, P1
Pergolizzi, JV; Raffa, RB; Segarnick, DJ; Tallarida, RJ1
Offord, J; Thorpe, AJ1
Ceyhan, D; Güleç, MS1
Bostanci, N; Sarıkaya, R; Yüksel, M1
Masramón, X; Navarro, A; Pérez, C; Rejas, J; Saldaña, MT3
Ben-Joseph, RH; Birnbaum, HG; Ivanova, JI; Kantor, E; Kirson, NY; Puenpatom, RA; Summers, KH; Wei, R1
Bockbrader, HN; Burger, P; Chapel, S; Janiczek, N; Miller, R; Wesche, D1
Delahoy, P; Marschner, IC; Thompson, S1
Goulis, DG; Kouvelas, D; Papazisis, G; Toulis, KA; Tzellos, TG; Vakfari, A; Zampeli, VA1
Cushman, T; Gardner, H; McDonagh, M; Siler, AC; Yanit, K1
Manabe, H; Matsumoto, Y; Miura, H; Tsukumo, Y; Yano, H1
Corazza, O; D'Offizi, S; Davey, Z; Deluca, P; Di Furia, L; Di Melchiorre, G; Farré, M; Flesland, L; Majava, A; Mannonen, M; Pagani, S; Peltoniemi, T; Pezzolesi, C; Piccione, M; Scherbaum, N; Schifano, F; Siemann, H; Skutle, A; Torrens, M; van der Kreeft, P1
Armstrong, EP; Malone, DC; McCarberg, B; Panarites, CJ; Pham, SV1
Dooley, DJ; Gerhardt, GA; Huettl, P; Pomerleau, F; Quintero, JE1
Feuerstein, TJ; Freiman, TM; Kammerer, M; Rassner, MP1
Carloni, F; Castellani, C; Drudi, F; Possenti, C; Santelmo, C; Tassinari, D1
Ceyhan, D; Erdoğan, G; Güleç, S1
Bittner, S; Göbel, K; Höhn, K; Kleinschnitz, C; Meuth, SG; Wiendl, H1
Hidaka, I; Ifuku, M; Inada, E; Iseki, M; Komatus, S; Morita, Y1
Gopal, K; Gross, GW; Lukas, TJ; Moore, EJ; Wu, C1
Ahl, J; Irving, GA; Malcolm, SK; Risser, RC; Robinson, MJ; Skljarevski, V; Tanenberg, RJ1
Black, DL; Caplan, YH; Cone, EJ; Depriest, A; Heltsley, R; Robert, T1
Bhatnagar, S; Goyal, GN; Mishra, S; Rana, SP; Upadhya, SP1
Navarro-Artieda, R; Planas-Comes, A; Rejas-Gutiérrez, J; Sicras-Mainar, A1
Argoff, CE1
Filip, D; Florek-Luszczki, M; Luszczki, JJ1
Carlos, F; Dueñas, H; Galindo-Suárez, RM; Ramírez-Gámez, J; Ramos, E1
Villaseca, P1
Kecik, Y; Ozgencil, E; Tuna, H; Yalcin, S; Yorukoglu, D1
Harnett, J; Mardekian, J; Udall, M1
Jones, JM; Kohli, M; Loprinzi, CL1
Weinbroum, AA1
Kato, A; Ogawa, K; Shinohara, S; Takasu, K; Yoneda, Y1
Miyazaki, R; Yamamoto, T1
Bonin, RP; Clarke, H; Englesakis, M; Katz, J; Orser, BA; Wijeysundera, DN1
Steiger, A1
Kohno, T; Obata, H1
Bramness, JG; Engeland, A; Sandvik, P; Skurtveit, S1
Bortolotto, V; Canonico, PL; Cuccurazzu, B; Francese, MT; Grilli, M; Meneghini, V; Ubezio, F; Valente, MM1
Faramazi, A; Pakravan, M; Roshani, M; Yaseri, M; Yazdani, S1
Kleinman, NL; Labiner, DM; Martin, RC; Sadosky, A; Seid, J1
Atalay, H; Biyik, Z; Gaipov, A; Guney, F; Solak, Y; Turk, S2
Brunton, LM; Laporte, DM1
Chaparro, LE; Gilron, I; Moore, RA; Wiffen, PJ1
de Biase, S; Gigli, GL; Lorenzut, S; Merlino, G; Valente, M1
Ichigo, S; Imai, A; Matsunami, K; Takagi, H1
Buvanendran, A1
Atalay, H; Biyik, Z; Covic, A; Gaipov, A; Goldsmith, D; Guney, F; Kanbay, M; Solak, Y; Turk, S1
Bockbrader, HN; Budhwani, MN; Wesche, DL1
Brodbelt, DC; Chandler, KE; Craig, A; Driver, CJ; McGonnell, IM; Plessas, IN; Rusbridge, C; Volk, HA1
Keyhanfar, F; Shamsi Meymandi, M1
Becker, L; Halpern, R; Johnson, P; Sweeney, M1
Chahbouni, A; den Burger, JC; Sinjewel, A; Swart, EL; Veldkamp, AI; Vos, RM; Wilhelm, AJ1
Danhof, M; Della Pasqua, O; Nyberg, J; Taneja, A1
Paul, RK; Singh, NS; Torjman, MC; Wainer, IW1
Cohen, SM; Misono, S1
Fuzier, R; Guitton, E; Lapeyre-Mestre, M; Montastruc, JL; Serres, I1
Altamura, AC; Bareggi, S; Maffini, M; Mauri, MC; Moliterno, D; Paletta, S1
Gouda, AA; Malah, ZA1
Bollag, L; Landau, R; Ortner, C1
Baharani, J; Dasgupta, I; Rayner, H; Smith, S; Suresh, V1
Athanasakis, K; Karampli, E; Kyriopoulos, J; Lyras, L; Petrakis, I; Vitsou, E1
Fostini, AC; Girolomoni, G; Tessari, G1
Chronicle, EP; Linde, M; McCrory, DC; Mulleners, WM1
Martinc, B; Vovk, T1
Kim, SC; Landon, JE; Solomon, DH1
Chaparro, LE; Gilron, I; Moore, RA; Smith, SA; Wiffen, PJ1
Khadem, T; Stevens, V1
Li, M; Ran, B; Shi, Z; Yu, L1
Argoff, CE; Harden, RN; Kaye, AD; Kintanar, T1
Carroll, IR; Mackey, SC; Ruchelli, G; Schmidt, PC1
Márquez-Rivas, J; Mayorga-Buiza, MJ; Monge-Márquez, ME; Rivero-Garvía, M1
Navarro, R; Planas, A; Rejas, J; Sicras, A1
Häuser, W; Sommer, C; Üçeyler, N; Walitt, B2
Dotsikas, Y; Kostić, N; Malenović, A; Medenica, M1
Clemow, DB; Giaconia, JM; Risser, RC; Tanenberg, RJ1
Baird, CR; Colvin, LA; Fox, P1
Spence, D1
Aldington, D; Cole, P; Derry, S; Haanpaa, M; Hamunen, K; Kalso, EA; Lunn, MP; Moore, RA; Rice, AS; Wiffen, PJ1
Guy, S; Leff, L; Loh, E; Mehta, S; Teasell, R1
Birklein, F; Boess, FG; Happich, M; Schacht, A; Schneider, E; Wilhelm, S; Ziegler, D1
Hollmann, MW; Houweling, PL; Molag, ML; van Boekel, RL; van Haelst, IM; Verbrugge, SJ1
Moreno, LA; Ojeda, A1
Scheinfeld, N1
Aldington, DJ; Kalso, E; Moore, RA1
Bansal, KK; Jindal, P; Khurana, G; Sharma, JP1
Sanders, GJ1
Kremer, AE; Mettang, T1
Benoliel, R; Haviv, Y; Sharav, Y; Zadik, Y1
Hashimoto, R; Hosokawa, K; Mashimo, T; Nakae, A; Nakai, K1
Dwyer, JP; Jayasekera, C; Nicoll, A1
Ravindran, D1
Bramanti, P; Galuppo, M; Giacoppo, S; Mazzon, E1
Al Taher, WM; Bekawi, MS; El Wakeel, LM; Mageed, WM1
Schifano, F1
Callaghan, BC; Goutman, SA; Peltier, A1
Earley, CJ1
Huelin, R; Khankhel, Z; Mould, J; Parker, L; Wasiak, R1
Dworkin, RH; Farrar, JT; Gilron, I; Haynes, K; Katz, NP; Kerns, RD; Rappaport, BA; Rowbotham, MC; Tierney, AM; Troxel, AB; Turk, DC1
Gergov, M; Häkkinen, M; Kalso, E; Ojanperä, I; Vuori, E1
Irving, G; Malcolm, S; Raskin, J; Risser, RC; Tanenberg, RJ1
Grabnar, I; Martinc, B; Roškar, R; Vovk, T1
Comoglu, SS; Dolgun, H; Gurer, B; Kertmen, H; Sekerci, Z; Turkoglu, E; Yilmaz, ER1
Dijkers, M; Loh, E; McIntyre, A; Mehta, S; Teasell, RW1
Cho, YW; Jeon, JY; Lee, HB; Moon, HJ; Song, ML1
Dargan, PI; Green, JL; Kapil, V; Le Lait, MC; Wood, DM1
Ballanyi, K; Biggs, JE; Boakye, PA; Ganesan, N; Lantero, A; Smith, PA; Stemkowski, PL1
Pickering, G1
Deeb, S; Logan, BK; McKeown, DA; Scott, KS; Torrance, HJ; Wylie, FM1
Faktorovich, EG; Melwani, K1
Johnson, RW; Rice, AS1
Korkmaz, M; Sarıtaş, TB; Sarıtaş, ZK; Sevimli, A1
Aldington, D; Derry, S; Moore, RA; Wiffen, PJ1
Edwards, L1
Kim, SC; Landon, JE; Lee, YC1
Arnold, RM; Pruskowski, J1
Baftiu, A; Beiske, G; Burns, ML; Johannessen Landmark, C; Johannessen, SI1
Guo, W; Han, WJ; Hong, ZY; Huang, ZL; Li, YD; Liu, YY; Qu, WM; Wang, TX; Yin, D1
Liu, Y; Qian, C; Yang, M1
Atherton, PJ; Lafky, J; Loprinzi, CL; Pachman, DR; Ruddy, KJ; Seisler, D; Shinde, SS; Soori, G1
Clark, K; Currow, DC; Doogue, M; Lovell, M; Quinn, SJ; Sanderson, C1
Inoue, Y; Paulus, W; Trenkwalder, C; Winkelmann, J1
Esin, OR; Esin, RG; Sitnova, MA1
Bellows, BK; LaFleur, J; Nelson, RE; Oderda, GM1
Babu, VA; Bhyrapuneni, G; Goura, V; Jayarajan, P; Nirogi, R; Shinde, A; Yathavakilla, S1
Cho, YJ; Hwang, SH; Jeong, YM; Kang, JM; Park, IJ1
Kiss, G1
Cregg, R; Gubbay, AN; Ng, SC; Stasiowska, MK1
Kokki, H; Kokki, M; Sjövall, S1
Abdullah, KG; Agrawal, B; Alvin, MD; Benzel, EC; Khalaf, T; Krishnaney, AA; Lubelski, D; Mazanec, DJ; Mroz, TE; Thompson, NR1
Reddi, D1
Kumar, A; Niraj, RR; Piplani, S; Pushp, A; Saini, V1
Marshman, LA; Plummer, D; Robertson, K1
Aguilar Navarro, S; Mimenza Alvarado, A1
Trojano, M1
Hwang, SH; Kim, G; Ko, G; Lee, YJ; Park, IJ1
Lawrence, R1
Kwatra, SG; Matsuda, KM; Schonfeld, AR; Sharma, D1
Badiola, IJ1
Chiappini, S; Schifano, F1
Classon, B; Edenius, C; Grabowska, U; Henderson, I; Hewitt, E; Lindström, E; Malcangio, M; Pitcher, T; Rizoska, B; Sahlberg, BL; Tunblad, K1
Calandre, EP; Rico-Villademoros, F; Slim, M1
Stannard, C1
Kawakami, J; Naito, T; Yagi, T; Yoshikawa, N1
Gibbs, LM; Lindsay, TJ; Snyder, MJ1
Almas, M; French, J; Friedman, D; Glue, P; Knapp, L; Pitman, V; Posner, HB; Yardi, N1
Hamilton, TW; Pandit, HG; Strickland, LH1
Ding, W; Mao, Y; Wu, L1
Fleischer, AB; Pongcharoen, P1
Şavk, E1
Mettang, T1
Kim, J; Kim, S; Ko, S; Oh, T1
Bursová, M; Čabala, R; Coufal, P; Hložek, T1
Ardid, D; Boudieu, L; Carvalho, FA; Eschalier, A; Gelot, A; Lashermes, A; Matricon, J; Meleine, M; Muller, E; Silberberg, C; Theodorou, V1
Behar, R; Jensen, TS; Li, C; Markman, JD; Parsons, B; Sadosky, AB; Semel, D1
Navarro-Artieda, R; Pérez-Páramo, M; Rejas-Gutiérrez, J; Sicras-Mainar, A2
Alcántara Montero, A; Ibor Vidal, PJ1
Cohen, SM; Giliberto, JP; Misono, S1
Almoznino, G; Benoliel, R; Haviv, Y; Sharav, Y1
Evoy, KE; Morrison, MD; Saklad, SR1
Rizzolo, D; Wright, ME1
Cherrier, C; Di Patrizio, P; Poucher, AC; Poucher, M1
AlAmri, R; Bhandari, M; Devereaux, PJ; Gilron, I; Kamath, S; Rajarathinam, M; Shanthanna, H; Thabane, L2
Attal, N; Baron, R; Bennett, DL; Bouhassira, D; Colloca, L; Dickenson, AH; Dworkin, RH; Eccleston, C; Finnerup, NB; Freeman, R; Kalso, E; Ludman, T; Raja, SN; Truini, A; Yarnitsky, D1
Abe, H; Hozumi, J; Ikegami, K; Inoue, R; Kawahara, K; Kogure, T; Sumitani, M; Yamada, Y1
Kreitz, T; Kurd, MF; Schroeder, G; Vaccaro, AR1
Micov, A; Pecikoza, U; Stepanović-Petrović, R; Tomić, M1
Andrews, R; Nahar, L; Patel, R; Paterson, S; Smith, A1
Wee, TC1
Atkinson, LZ; Awad, A; Cipriani, A; Forrest, A; Geddes, JR; Harrison, PJ; Houghton, KT; Stockton, S1
Beloeil, H; Carles, M; Marret, E; Martinez, V1
Audrey, S; Burnell, ES; Henderson, G; Hickman, M; Hill, R; Ingle, S; Lyndon, A; Wells, C1
Katz, P; Liedgens, H; Pegoraro, V1
Jermendy, G; Kempler, P; Keresztes, K; Körei, A; Lengyel, C; Martos, T; Nyiraty, S; Putz, Z; Stirban, A; Várkonyi, T1
Grant, MC; Wick, EC; Wu, CL1
Antoniou, T; Gomes, T; Ho, JM; Juurlink, DN; Luo, J; Macdonald, EM; Mamdani, MM1
Cocchi, G; D'Alessandro, R; Mostacci, B; Poluzzi, E; Tinuper, P1
Askin, N; Bohm, C; Komenda, P; Lerner, B; Rigatto, C; Shaw, J; Simonsen, E; Tangri, N1
Busse, JW; Choi, S; Clarke, H; Devereaux, PJ; Dhaliwal, J; Khan, JS; Rai, AS1
Brett, AS; Goodman, CW3
Clinch, J; Cooper, TE; Heathcote, LC; Howard, R; Krane, E; Lord, SM; Schechter, N; Sethna, N; Wiffen, PJ; Wood, C1
Farver, D; Heeren, N1
Amin, A; Kaul, I; Meyer, WJ; Rosenberg, L; Rosenberg, M1
Inada, E; Iseki, M; Kumakura, S; Nagaoka, I; Someya, A; Yamaguchi, K1
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Allen, R; Burke, L; Dworkin, RH; Farrar, JT; Gewandter, JS; Gilron, I; Katz, NP; Markman, JD; Marshall, SF; Patel, KV; Resnick, M; Rice, ASC; Rowbotham, MC; Smith, SM; Turk, DC; Vanhove, GF; Wasan, AD; Zhang, S1
Almansa, C; Guallar, V; Kotev, M; Pascual, R; Soliva, R1
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Hampton, S; Nicholls, G; Samios, P1
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Kane, J; Montastruc, F; Rahman, A; Renoux, C1
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Benarroch, EE1
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Turgeon, AF; Verret, M1
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Chong, E; Kim, DJ; Kim, SM; Lee, SY; Oh, H1

Reviews

200 review(s) available for gabapentin and pregabalin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Newer anticonvulsants in the treatment of bipolar disorder.
    The Journal of clinical psychiatry, 2004, Volume: 65 Suppl 10

    Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Depressive Disorder; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide

2004
'Protective premedication': an option with gabapentin and related drugs? A review of gabapentin and pregabalin in in the treatment of post-operative pain.
    Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:9

    Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Pain, Postoperative; Peripheral Nervous System Diseases; Pregabalin; Randomized Controlled Trials as Topic

2004
Practice parameter: treatment of postherpetic neuralgia: an evidence-based report of the Quality Standards Subcommittee of the American Academy of Neurology.
    Neurology, 2004, Sep-28, Volume: 63, Issue:6

    Topics: Acupuncture Analgesia; Administration, Cutaneous; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Anticonvulsants; Antidepressive Agents, Tricyclic; Antiviral Agents; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Evaluation; Evidence-Based Medicine; Excitatory Amino Acid Antagonists; Forecasting; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Iontophoresis; Lidocaine; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic; Receptors, N-Methyl-D-Aspartate

2004
[Symptomatic treatment of painful diabetic neuropathy].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 6

    Topics: Amines; Anti-Asthmatic Agents; Anticonvulsants; Antidepressive Agents; Antitussive Agents; Cyclohexanecarboxylic Acids; Dextromethorphan; Diabetic Neuropathies; Fructose; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Humans; Lamotrigine; Mexiletine; Nerve Fibers; Posterior Horn Cells; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sodium Channels; Topiramate; Triazines

2005
The mechanisms of action of gabapentin and pregabalin.
    Current opinion in pharmacology, 2006, Volume: 6, Issue:1

    Topics: Amines; Amino Acid Transport Systems; Analgesics; Animals; Anticonvulsants; Calcium Channels; Central Nervous System; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Pregabalin; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate

2006
Pregabalin in neuropathic pain: a more "pharmaceutically elegant" gabapentin?
    The American journal of geriatric pharmacotherapy, 2005, Volume: 3, Issue:4

    Topics: Aged; Amines; Analgesics, Non-Narcotic; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Peripheral Nervous System Diseases; Pregabalin

2005
Novel anticonvulsant drugs.
    Pharmacology & therapeutics, 2007, Volume: 113, Issue:1

    Topics: Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Piracetam; Pregabalin; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide

2007
Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed?
    Clinical pharmacokinetics, 2006, Volume: 45, Issue:11

    Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Pregabalin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2006
Pharmacology and mechanism of action of pregabalin: the calcium channel alpha2-delta (alpha2-delta) subunit as a target for antiepileptic drug discovery.
    Epilepsy research, 2007, Volume: 73, Issue:2

    Topics: Amines; Amino Acid Sequence; Animals; Anticonvulsants; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Gabapentin; gamma-Aminobutyric Acid; Molecular Sequence Data; Pregabalin; Protein Conformation

2007
Adjuvant analgesics for the treatment of neuropathic pain: evaluating efficacy and safety profiles.
    The Journal of family practice, 2007, Volume: 56, Issue:2 Suppl Pa

    Topics: Administration, Cutaneous; Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents; Arthritis; Chemotherapy, Adjuvant; Chronic Disease; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Diagnosis, Differential; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Low Back Pain; Pain; Pain Measurement; Pain, Postoperative; Practice Guidelines as Topic; Pregabalin; Wounds and Injuries

2007
[A new aspect in the research on antiepileptic drugs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2007, Volume: 129, Issue:2

    Topics: Acetamides; Amines; Animals; Anticonvulsants; Benzodiazepines; Carbamates; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Humans; Lacosamide; Levetiracetam; Phenylenediamines; Piracetam; Pregabalin; Pregnanolone; Pyrrolidinones; Triazoles

2007
Postoperative pain--clinical implications of basic research.
    Best practice & research. Clinical anaesthesiology, 2007, Volume: 21, Issue:1

    Topics: Amines; Analgesia; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Pain, Postoperative; Pregabalin; Receptors, N-Methyl-D-Aspartate

2007
Ca2+ channel alpha2-delta ligands for the treatment of neuropathic pain.
    Journal of medicinal chemistry, 2007, May-31, Volume: 50, Issue:11

    Topics: Amines; Analgesics; Animals; Anticonvulsants; Calcium Channels; Carboxylic Acids; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Mice; Mice, Mutant Strains; Pain; Peripheral Nervous System Diseases; Pregabalin; Prodrugs

2007
The P/Q-type voltage-dependent calcium channel: a therapeutic target in spinocerebellar ataxia type 6.
    Acta neurologica Scandinavica, 2007, Volume: 115, Issue:5

    Topics: Amines; Anticonvulsants; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Spinocerebellar Ataxias

2007
Do surgical patients benefit from perioperative gabapentin/pregabalin? A systematic review of efficacy and safety.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:6

    Topics: Amines; Cyclohexanecarboxylic Acids; Dizziness; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Perioperative Care; Pregabalin; Randomized Controlled Trials as Topic

2007
Diabetic neuropathy: new strategies for treatment.
    Diabetes, obesity & metabolism, 2008, Volume: 10, Issue:2

    Topics: Aldehyde Reductase; Amines; Analgesics; Anticonvulsants; Antidepressive Agents; Antioxidants; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Thiamine; Thioctic Acid; Thiophenes

2008
Pharmacological treatment of fibromyalgia and other chronic musculoskeletal pain.
    Best practice & research. Clinical rheumatology, 2007, Volume: 21, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Amines; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Pregabalin; Selective Serotonin Reuptake Inhibitors; Tramadol; Treatment Outcome

2007
A cost-effectiveness comparison of desipramine, gabapentin, and pregabalin for treating postherpetic neuralgia.
    Journal of the American Geriatrics Society, 2007, Volume: 55, Issue:8

    Topics: Aged; Amines; Analgesics; Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Desipramine; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Neuralgia, Postherpetic; Pregabalin; Randomized Controlled Trials as Topic; Severity of Illness Index

2007
GABAergic drugs for the treatment of migraine.
    CNS & neurological disorders drug targets, 2007, Volume: 6, Issue:4

    Topics: Acute Disease; Amines; Animals; Cyclohexanecarboxylic Acids; Fructose; GABA Agents; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders; Neuroprotective Agents; Pregabalin; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Topiramate; Valproic Acid

2007
Gabapentin and pregabalin for chronic neuropathic and early postsurgical pain: current evidence and future directions.
    Current opinion in anaesthesiology, 2007, Volume: 20, Issue:5

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Forecasting; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Pain; Pain, Postoperative; Pregabalin

2007
Treatment of painful neuropathy.
    Current opinion in neurology, 2007, Volume: 20, Issue:5

    Topics: Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Peripheral Nervous System Diseases; Pregabalin; Selective Serotonin Reuptake Inhibitors

2007
Managing neuropathic pain.
    The Journal of the American Osteopathic Association, 2007, Volume: 107, Issue:10 Suppl 6

    Topics: Amines; Analgesics, Opioid; Anticonvulsants; Calcium Channel Blockers; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Disease Progression; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Peripheral Nervous System Diseases; Pregabalin; Receptors, N-Methyl-D-Aspartate; United States

2007
The new antiepileptic drugs.
    Archives of disease in childhood. Education and practice edition, 2007, Volume: 92, Issue:6

    Topics: Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsies, Partial; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Oxcarbazepine; Piracetam; Pregabalin; Topiramate; Triazines; Vigabatrin; Zonisamide

2007
Enriched enrollment: definition and effects of enrichment and dose in trials of pregabalin and gabapentin in neuropathic pain. A systematic review.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:2

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic; Treatment Outcome

2008
Update on fibromyalgia therapy.
    The American journal of medicine, 2008, Volume: 121, Issue:7

    Topics: Amines; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents; Complementary Therapies; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Exercise Therapy; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin

2008
Efficacy of pregabalin and gabapentin for neuropathic pain in spinal-cord injury: an evidence-based evaluation of the literature.
    European journal of clinical pharmacology, 2008, Volume: 64, Issue:9

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pregabalin; Spinal Cord Injuries

2008
Pain relief by gabapentin and pregabalin via supraspinal mechanisms after peripheral nerve injury.
    Journal of neuroscience research, 2008, Nov-15, Volume: 86, Issue:15

    Topics: Amines; Analgesics; Animals; Brain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Neuralgia; Peripheral Nerve Injuries; Pregabalin; Synaptic Transmission

2008
Practical management strategies for the chronic pain patient.
    The Journal of family practice, 2007, Volume: 56, Issue:8 Suppl Ho

    Topics: Administration, Cutaneous; Amines; Analgesics; Antidepressive Agents, Tricyclic; Carbamazepine; Chronic Disease; Clinical Protocols; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Monitoring; Drug Tolerance; Duloxetine Hydrochloride; Family Practice; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Middle Aged; Pain; Practice Guidelines as Topic; Pregabalin; Randomized Controlled Trials as Topic; Substance-Related Disorders; Thiophenes; Treatment Outcome

2007
[Mechanisms of the development of neuropathic pain and its treatment].
    Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association, 2008, Volume: 77, Issue:3

    Topics: Amines; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Leprosy; Lidocaine; Neuralgia; Posterior Horn Cells; Pregabalin; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers

2008
Mechanisms of analgesia by gabapentin and pregabalin--calcium channel alpha2-delta [Cavalpha2-delta] ligands.
    Pain, 2009, Volume: 142, Issue:1-2

    Topics: Amines; Analgesics; Animals; Calcium Channels; Cell Adhesion; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Biological; Pregabalin; Protein Binding; Protein Transport; Signal Transduction

2009
Meta-analysis of duloxetine vs. pregabalin and gabapentin in the treatment of diabetic peripheral neuropathic pain.
    BMC neurology, 2009, Feb-10, Volume: 9

    Topics: Amines; Analgesics; Analysis of Variance; Bayes Theorem; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Peripheral Nervous System; Pregabalin; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome

2009
Pregabalin in the treatment of chronic pain: an overview.
    Clinical drug investigation, 2009, Volume: 29, Issue:3

    Topics: Amines; Analgesics, Non-Narcotic; Animals; Calcium Channels; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Guidelines as Topic; Humans; Pain; Peripheral Nervous System Diseases; Pregabalin

2009
[Empirical evidence for the use of anticonvulsants in personality disorders].
    Fortschritte der Neurologie-Psychiatrie, 2009, Volume: 77, Issue:3

    Topics: Amines; Anticonvulsants; Borderline Personality Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Personality Disorders; Pregabalin; Randomized Controlled Trials as Topic; Topiramate; Triazines; Valproic Acid

2009
Treatment of fibromyalgia syndrome with gabapentin and pregabalin--a meta-analysis of randomized controlled trials.
    Pain, 2009, Volume: 145, Issue:1-2

    Topics: Amines; Analgesics; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Databases, Bibliographic; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Randomized Controlled Trials as Topic; Reproducibility of Results

2009
Multimodal analgesia for hip arthroplasty.
    The Orthopedic clinics of North America, 2009, Volume: 40, Issue:3

    Topics: Amines; Analgesia; Analgesics; Anesthetics, Local; Arthroplasty, Replacement, Hip; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Pregabalin

2009
Gabapentin and pregabalin for the acute post-operative pain management. A systematic-narrative review of the recent clinical evidences.
    Current drug targets, 2009, Volume: 10, Issue:8

    Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain, Postoperative; Pregabalin; Randomized Controlled Trials as Topic

2009
Fibromyalgia and headache disorders.
    Current pain and headache reports, 2009, Volume: 13, Issue:5

    Topics: Amines; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders; Humans; Meta-Analysis as Topic; Pregabalin; Randomized Controlled Trials as Topic

2009
Treatment of neuropathic pain: an overview of recent guidelines.
    The American journal of medicine, 2009, Volume: 122, Issue:10 Suppl

    Topics: Amines; Analgesics; Analgesics, Opioid; Anesthetics, Local; Antidepressive Agents; Canada; Cyclohexanecarboxylic Acids; Europe; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; International Cooperation; Lidocaine; Neuralgia; Practice Guidelines as Topic; Pregabalin; Selective Serotonin Reuptake Inhibitors; Societies, Medical; Tramadol

2009
Evidence for sensory neuropathy and pharmacologic management.
    Otolaryngologic clinics of North America, 2010, Volume: 43, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Amines; Amitriptyline; Anticonvulsants; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Vagus Nerve Diseases; Virus Diseases

2010
Recommendations for the pharmacological management of neuropathic pain: an overview and literature update.
    Mayo Clinic proceedings, 2010, Volume: 85, Issue:3 Suppl

    Topics: Acetamides; Amines; Analgesics; Analgesics, Opioid; Anesthetics, Local; Antidepressive Agents; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Lacosamide; Neuralgia; Practice Guidelines as Topic; Pregabalin; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors

2010
The anti-allodynic alpha(2)delta ligand pregabalin inhibits the trafficking of the calcium channel alpha(2)delta-1 subunit to presynaptic terminals in vivo.
    Biochemical Society transactions, 2010, Volume: 38, Issue:2

    Topics: Amines; Analgesics; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Models, Biological; Neuralgia; Pregabalin; Presynaptic Terminals; Protein Transport

2010
Central sensitization and Ca(V)α₂δ ligands in chronic pain syndromes: pathologic processes and pharmacologic effect.
    The journal of pain, 2010, Volume: 11, Issue:12

    Topics: Amines; Analgesics; Animals; Calcium Channels; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Neuronal Plasticity; Pain; Pregabalin

2010
Psychiatric concerns in pediatric epilepsy.
    Child and adolescent psychiatric clinics of North America, 2010, Volume: 19, Issue:2

    Topics: Adolescent; Amines; Anxiety Disorders; Bipolar Disorder; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Cyclohexanols; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Mental Disorders; Norepinephrine; Pregabalin; Selective Serotonin Reuptake Inhibitors; Valproic Acid; Venlafaxine Hydrochloride; Young Adult

2010
Oxycodone combinations for pain relief.
    Drugs of today (Barcelona, Spain : 1998), 2010, Volume: 46, Issue:6

    Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; Oxycodone; Pain; Pregabalin

2010
The alpha2-delta protein: an auxiliary subunit of voltage-dependent calcium channels as a recognized drug target.
    Current opinion in investigational drugs (London, England : 2000), 2010, Volume: 11, Issue:7

    Topics: Amines; Animals; Brain; Calcium Channel Blockers; Calcium Channels; Cyclohexanecarboxylic Acids; Drug Delivery Systems; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; Genomics; Humans; Models, Biological; Pregabalin; Protein Subunits

2010
[Is postoperative pain only a nociceptive pain?].
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2010, Volume: 22, Issue:2

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Nociceptors; Pain, Postoperative; Pregabalin; Treatment Outcome

2010
A comparison of the pharmacokinetics and pharmacodynamics of pregabalin and gabapentin.
    Clinical pharmacokinetics, 2010, Volume: 49, Issue:10

    Topics: Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Pregabalin

2010
Pregabalin versus gabapentin in partial epilepsy: a meta-analysis of dose-response relationships.
    BMC neurology, 2010, Nov-01, Volume: 10

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Randomized Controlled Trials as Topic

2010
Gabapentin and pregabalin in the treatment of fibromyalgia: a systematic review and a meta-analysis.
    Journal of clinical pharmacy and therapeutics, 2010, Volume: 35, Issue:6

    Topics: Amines; Analgesics, Non-Narcotic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Outcome Assessment, Health Care; Pain; Pregabalin; Randomized Controlled Trials as Topic; Treatment Outcome

2010
Systematic review of the comparative effectiveness of antiepileptic drugs for fibromyalgia.
    The journal of pain, 2011, Volume: 12, Issue:4

    Topics: Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin

2011
Cost-effectiveness analysis of a new 8% capsaicin patch compared to existing therapies for postherpetic neuralgia.
    Current medical research and opinion, 2011, Volume: 27, Issue:5

    Topics: Administration, Topical; Amines; Anesthetics, Local; Antidepressive Agents, Tricyclic; Capsaicin; Clinical Trials as Topic; Costs and Cost Analysis; Cyclohexanecarboxylic Acids; Dopamine Uptake Inhibitors; Duloxetine Hydrochloride; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Male; Markov Chains; Neuralgia, Postherpetic; Pregabalin; Quality of Life; Sensory System Agents; Thiophenes; Transdermal Patch

2011
[Neuropathic pain in oncology. Novel evidence for clinical practice].
    Recenti progressi in medicina, 2011, Volume: 102, Issue:5

    Topics: Amines; Amitriptyline; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Neoplasms; Neuralgia; Pregabalin; Tramadol; Treatment Outcome

2011
[Pregabalin and gabapentin in multiple sclerosis: clinical experiences and therapeutic implications].
    Der Nervenarzt, 2011, Volume: 82, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Antineoplastic Agents; Carbamazepine; Cohort Studies; Cyclohexanecarboxylic Acids; Disability Evaluation; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Male; Middle Aged; Mitoxantrone; Multiple Sclerosis; Neurologic Examination; Pregabalin; Retrospective Studies; Triazines; Valproic Acid; Young Adult

2011
Review of current guidelines on the care of postherpetic neuralgia.
    Postgraduate medicine, 2011, Volume: 123, Issue:5

    Topics: Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Capsaicin; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Neuralgia, Postherpetic; Practice Guidelines as Topic; Pregabalin; Primary Health Care; Tramadol; Transdermal Patch

2011
Non-estrogen conventional and phytochemical treatments for vasomotor symptoms: what needs to be known for practice.
    Climacteric : the journal of the International Menopause Society, 2012, Volume: 15, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Anticonvulsants; Cimicifuga; Clonidine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Phytoestrogens; Phytotherapy; Plant Extracts; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sweating; Vasomotor System

2012
Androgen deprivation therapy-associated vasomotor symptoms.
    Asian journal of andrology, 2012, Volume: 14, Issue:2

    Topics: Amines; Androgen Antagonists; Anticonvulsants; Antidepressive Agents; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Male; Pregabalin; Prostatic Neoplasms; Vasomotor System

2012
Non-opioid IV adjuvants in the perioperative period: pharmacological and clinical aspects of ketamine and gabapentinoids.
    Pharmacological research, 2012, Volume: 65, Issue:4

    Topics: Adjuvants, Pharmaceutic; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Pain, Postoperative; Perioperative Period; Pregabalin

2012
The prevention of chronic postsurgical pain using gabapentin and pregabalin: a combined systematic review and meta-analysis.
    Anesthesia and analgesia, 2012, Volume: 115, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Evidence-Based Medicine; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Male; Middle Aged; Odds Ratio; Pain Measurement; Pain, Postoperative; Perioperative Period; Pregabalin; Time Factors; Treatment Outcome; Young Adult

2012
[Mechanisms of action of therapeutic agents in the treatment of chronic pain in the spinal cord].
    Masui. The Japanese journal of anesthesiology, 2011, Volume: 60 Suppl

    Topics: Amines; Antidepressive Agents; Calcium Channel Blockers; Chronic Pain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Pregabalin; Receptors, Opioid, mu; Selective Serotonin Reuptake Inhibitors; Spinal Cord; Tramadol

2011
Use of gabapentin and pregabalin for hand surgery patients.
    The Journal of hand surgery, 2012, Volume: 37, Issue:7

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hand; Humans; Neuralgia; Pain, Postoperative; Pregabalin

2012
Combination pharmacotherapy for the treatment of neuropathic pain in adults.
    The Cochrane database of systematic reviews, 2012, Jul-11, Issue:7

    Topics: Acetaminophen; Adult; Amines; Analgesics; Antidepressive Agents, Tricyclic; Benzodiazepinones; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; N-Methylaspartate; Neuralgia; Nortriptyline; Phenylurea Compounds; Pregabalin; Thioctic Acid; Tramadol

2012
ADMET considerations for restless leg syndrome drug treatments.
    Expert opinion on drug metabolism & toxicology, 2012, Volume: 8, Issue:10

    Topics: Amines; Anticonvulsants; Benzothiazoles; Carbamates; Cyclohexanecarboxylic Acids; Dopamine Agents; Dopamine Agonists; Ergolines; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Levodopa; Neuralgia; Pramipexole; Pregabalin; Randomized Controlled Trials as Topic; Restless Legs Syndrome; Tetrahydronaphthalenes; Thiophenes; Treatment Outcome

2012
New generation nonhormonal management for hot flashes.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2013, Volume: 29, Issue:1

    Topics: Amines; Anticonvulsants; Citalopram; Cyclohexanecarboxylic Acids; Estrogen Replacement Therapy; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Pregabalin; Selective Serotonin Reuptake Inhibitors

2013
Use of specific neuromodulators in the treatment of chronic, idiopathic cough: a systematic review.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2013, Volume: 148, Issue:3

    Topics: Amines; Amitriptyline; Baclofen; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents; Pregabalin; Quality of Life

2013
Understanding the pharmacokinetics of anxiolytic drugs.
    Expert opinion on drug metabolism & toxicology, 2013, Volume: 9, Issue:4

    Topics: Adrenergic beta-Antagonists; Amines; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Atenolol; Benzodiazepines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Histamine Antagonists; Humans; Hydroxyzine; Pregabalin; Propranolol; Sleep Initiation and Maintenance Disorders

2013
Chronic pain after childbirth.
    International journal of obstetric anesthesia, 2013, Volume: 22, Issue:2

    Topics: Acute Pain; Adrenergic alpha-Agonists; Adult; Amines; Analgesics; Anesthetics, Dissociative; Cesarean Section; Chronic Pain; Clonidine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Ketamine; Magnesium Sulfate; Nerve Block; Oxytocin; Pain, Postoperative; Parturition; Pelvic Pain; Peritoneum; Pregabalin; Pregnancy; Risk Factors; Uterus

2013
Prurigo nodularis: an update on etiopathogenesis and therapy.
    The Journal of dermatological treatment, 2013, Volume: 24, Issue:6

    Topics: Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Dermatologic Agents; Epidermis; Female; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Physical Therapy Modalities; Pregabalin; Prurigo; Sex Factors; Skin

2013
Gabapentin or pregabalin for the prophylaxis of episodic migraine in adults.
    The Cochrane database of systematic reviews, 2013, Jun-24, Issue:6

    Topics: Adult; Amines; Anticonvulsants; Carbamates; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders; Pregabalin; Randomized Controlled Trials as Topic

2013
Pharmacotherapy for the prevention of chronic pain after surgery in adults.
    The Cochrane database of systematic reviews, 2013, Jul-24, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ibuprofen; Ketamine; Male; Mexiletine; Pain, Postoperative; Pregabalin; Randomized Controlled Trials as Topic

2013
Therapeutic options for the treatment of postherpetic neuralgia: a systematic review.
    Journal of pain & palliative care pharmacotherapy, 2013, Volume: 27, Issue:3

    Topics: Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Approval; Gabapentin; gamma-Aminobutyric Acid; Humans; Medication Adherence; Neuralgia, Postherpetic; Off-Label Use; Pregabalin; Quality of Life; United States; United States Food and Drug Administration

2013
Gabapentin and pregabalin in the management of postoperative pain after lumbar spinal surgery: a systematic review and meta-analysis.
    Spine, 2013, Oct-15, Volume: 38, Issue:22

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lumbar Vertebrae; Pain, Postoperative; Pregabalin; Randomized Controlled Trials as Topic; Treatment Outcome

2013
Evidence-based guidance for the management of postherpetic neuralgia in primary care.
    Postgraduate medicine, 2013, Volume: 125, Issue:4

    Topics: Amines; Analgesics; Capsaicin; Carbamates; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia, Postherpetic; Practice Guidelines as Topic; Pregabalin; Primary Health Care

2013
Perioperative gabapentinoids: choice of agent, dose, timing, and effects on chronic postsurgical pain.
    Anesthesiology, 2013, Volume: 119, Issue:5

    Topics: Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Perioperative Care; Pregabalin

2013
Anticonvulsants for fibromyalgia.
    The Cochrane database of systematic reviews, 2013, Oct-16, Issue:10

    Topics: Acetamides; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Lacosamide; Levetiracetam; Piracetam; Pregabalin

2013
Antiepileptic drugs for neuropathic pain and fibromyalgia - an overview of Cochrane reviews.
    The Cochrane database of systematic reviews, 2013, Nov-11, Issue:11

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Intention to Treat Analysis; Neuralgia; Pain Measurement; Patient Dropouts; Pregabalin; Review Literature as Topic

2013
Anticonvulsant medication use for the management of pain following spinal cord injury: systematic review and effectiveness analysis.
    Spinal cord, 2014, Volume: 52, Issue:2

    Topics: Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain Management; Pregabalin; Randomized Controlled Trials as Topic; Spinal Cord Injuries

2014
['Postoperative pain treatment' practice guideline revised].
    Nederlands tijdschrift voor geneeskunde, 2013, Volume: 157, Issue:49

    Topics: Adult; Amines; Analgesia, Epidural; Child; Cyclohexanecarboxylic Acids; Dexamethasone; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Netherlands; Pain, Postoperative; Postoperative Nausea and Vomiting; Practice Guidelines as Topic; Pregabalin

2013
[Pain management in patients with liver cirrhosis].
    Gastroenterologia y hepatologia, 2014, Volume: 37, Issue:1

    Topics: Acetaminophen; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Hepatorenal Syndrome; Humans; Inactivation, Metabolic; Liver; Liver Cirrhosis; Narcotics; Nerve Block; Pain Management; Physical Therapy Modalities; Practice Guidelines as Topic; Pregabalin

2014
Treatment of hidradenitis supprurativa associated pain with nonsteroidal anti-inflammatory drugs, acetaminophen, celecoxib, gabapentin, pegabalin, duloxetine, and venlafaxine.
    Dermatology online journal, 2013, Nov-15, Volume: 19, Issue:11

    Topics: Acetaminophen; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclohexanecarboxylic Acids; Cyclohexanols; Drug Therapy, Combination; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hidradenitis Suppurativa; Humans; Pain; Pain Management; Pregabalin; Pyrazoles; Selective Serotonin Reuptake Inhibitors; Sulfonamides; Thiophenes; Venlafaxine Hydrochloride

2013
Uremic pruritus.
    Kidney international, 2015, Volume: 87, Issue:4

    Topics: Acupuncture Therapy; Amines; Anti-Inflammatory Agents; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; gamma-Linolenic Acid; Humans; Morphinans; Naltrexone; Narcotic Antagonists; Pentoxifylline; Phototherapy; Pregabalin; Pruritus; Receptors, Opioid, kappa; Renal Insufficiency, Chronic; Spiro Compounds; Tacrolimus; Thalidomide; Uremia

2015
Analgesia for the cirrhotic patient: a literature review and recommendations.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:7

    Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Contraindications; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Laxatives; Liver Cirrhosis; Neuralgia; Pain Management; Pain, Intractable; Pregabalin

2014
Use of natural compounds in the management of diabetic peripheral neuropathy.
    Molecules (Basel, Switzerland), 2014, Mar-05, Volume: 19, Issue:3

    Topics: Alkaloids; Amines; Animals; Biological Products; Cannabinoids; Complementary Therapies; Cyclohexanecarboxylic Acids; Diabetes Mellitus; Diabetic Neuropathies; Fatty Acids, Essential; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenols; Pregabalin

2014
Misuse and abuse of pregabalin and gabapentin: cause for concern?
    CNS drugs, 2014, Volume: 28, Issue:6

    Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Prescription Drug Misuse; Substance-Related Disorders

2014
Painful diabetic neuropathy.
    BMJ (Clinical research ed.), 2014, May-06, Volume: 348

    Topics: Amines; Analgesics; Analgesics, Opioid; Biopsy; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoglycemic Agents; Pregabalin; Sensory Thresholds; Skin; Thiophenes; Touch Perception

2014
Latest guidelines and advances for treatment of restless legs syndrome.
    The Journal of clinical psychiatry, 2014, Volume: 75, Issue:4

    Topics: Amines; Analgesics, Opioid; Carbamates; Cyclohexanecarboxylic Acids; Dopamine Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Iron Compounds; Pregabalin; Restless Legs Syndrome

2014
A systematic review of pharmacoeconomic studies for pregabalin.
    Pain practice : the official journal of World Institute of Pain, 2015, Volume: 15, Issue:1

    Topics: Amines; Analgesics; Anticonvulsants; Chronic Disease; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Economics, Pharmaceutical; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Health Services; Humans; Neuralgia; Pregabalin; Quality of Life; Quality-Adjusted Life Years; Spain; Sweden; United States

2015
Gabapentinoids are effective in decreasing neuropathic pain and other secondary outcomes after spinal cord injury: a meta-analysis.
    Archives of physical medicine and rehabilitation, 2014, Volume: 95, Issue:11

    Topics: Amines; Analgesics; Anxiety; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Depression; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pregabalin; Sleep Disorders, Intrinsic; Spinal Cord Injuries

2014
Antiepileptics for post-herpetic neuralgia in the elderly: current and future prospects.
    Drugs & aging, 2014, Volume: 31, Issue:9

    Topics: Aged; Aged, 80 and over; Amines; Anticonvulsants; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Health Services for the Aged; Humans; Neuralgia, Postherpetic; Polypharmacy; Pregabalin

2014
Efficacy and safety of pain relief medications after photorefractive keratectomy: review of prospective randomized trials.
    Journal of cataract and refractive surgery, 2014, Volume: 40, Issue:10

    Topics: Amines; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Eye Pain; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Photorefractive Keratectomy; Pregabalin; Prospective Studies; Randomized Controlled Trials as Topic; Treatment Outcome

2014
Clinical practice. Postherpetic neuralgia.
    The New England journal of medicine, 2014, Oct-16, Volume: 371, Issue:16

    Topics: Administration, Topical; Aged; Amines; Analgesics, Opioid; Anesthetics, Local; Antipyretics; Capsaicin; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Herpes Zoster Vaccine; Humans; Lidocaine; Neuralgia, Postherpetic; Pregabalin

2014
Nortriptyline for neuropathic pain in adults.
    The Cochrane database of systematic reviews, 2015, Jan-08, Volume: 1

    Topics: Amines; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Clomipramine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Morphine; Neuralgia; Nortriptyline; Pregabalin; Randomized Controlled Trials as Topic

2015
Vulvodynia.
    Clinical obstetrics and gynecology, 2015, Volume: 58, Issue:1

    Topics: Administration, Cutaneous; Amines; Analgesics; Anesthetics, Local; Antidepressive Agents; Cyclohexanecarboxylic Acids; Dyspareunia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Nerve Block; Patient Education as Topic; Physical Therapy Modalities; Pregabalin; Vulvodynia

2015
Restless legs syndrome-current therapies and management of augmentation.
    Nature reviews. Neurology, 2015, Volume: 11, Issue:8

    Topics: Amines; Analgesics, Opioid; Anticonvulsants; Cyclohexanecarboxylic Acids; Dopamine Agonists; Drug Synergism; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Iron Compounds; Iron Deficiencies; Practice Guidelines as Topic; Pregabalin; Pregnancy; Pregnancy Complications; Restless Legs Syndrome

2015
The efficacy of gabapentin/pregabalin in improving pain after tonsillectomy: A meta-analysis.
    The Laryngoscope, 2016, Volume: 126, Issue:2

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Pain, Postoperative; Pregabalin; Tonsillectomy

2016
[DRUG THERAPY OF NEUROPATHIC PAIN BASED ON THE LATEST RECOMMENDATIONS].
    Ideggyogyaszati szemle, 2015, Mar-30, Volume: 68, Issue:3-4

    Topics: Amines; Amitriptyline; Analgesics, Non-Narcotic; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Practice Guidelines as Topic; Pregabalin; Thiophenes

2015
Postoperative pain management.
    British journal of hospital medicine (London, England : 2005), 2015, Volume: 76, Issue:10

    Topics: Acetaminophen; Amines; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Management; Pain, Postoperative; Pregabalin

2015
Laparoscopic surgery: a narrative review of pharmacotherapy in pain management.
    Drugs, 2015, Volume: 75, Issue:16

    Topics: Acetaminophen; Adrenal Cortex Hormones; Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Laparoscopy; Pain Management; Pain, Postoperative; Pregabalin; Receptors, N-Methyl-D-Aspartate

2015
Preventing chronic postoperative pain.
    Anaesthesia, 2016, Volume: 71 Suppl 1

    Topics: Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Pain, Postoperative; Pregabalin; Thoracotomy

2016
Pregabalin and gabapentin for the treatment of sciatica.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016, Volume: 26

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pregabalin; Sciatica; Treatment Outcome

2016
Does preoperative administration of gabapentin/pregabalin improve postoperative nasal surgery pain?
    The Laryngoscope, 2016, Volume: 126, Issue:10

    Topics: Adolescent; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Nasal Surgical Procedures; Pain Measurement; Pain, Postoperative; Postoperative Complications; Postoperative Period; Pregabalin; Preoperative Care; Treatment Outcome; Vision Disorders; Young Adult

2016
Gabapentin and pregabalin for the treatment of chronic pruritus.
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:3

    Topics: Amines; Anti-Anxiety Agents; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Patient Satisfaction; Pregabalin; Pruritus; Quality of Life; Risk Assessment; Severity of Illness Index; Treatment Outcome

2016
Can Chronic Pain Be Prevented?
    Anesthesiology clinics, 2016, Volume: 34, Issue:2

    Topics: Acute Pain; Amines; Anesthesia, Conduction; Chronic Pain; Cyclohexanecarboxylic Acids; Epigenesis, Genetic; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Pain, Postoperative; Pregabalin

2016
Alpha
    Expert review of neurotherapeutics, 2016, Volume: 16, Issue:11

    Topics: Amines; Bridged Bicyclo Compounds; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Nervous System Diseases; Pregabalin

2016
Treating Painful Diabetic Peripheral Neuropathy: An Update.
    American family physician, 2016, Aug-01, Volume: 94, Issue:3

    Topics: Administration, Topical; Amines; Amitriptyline; Analgesics; Analgesics, Opioid; Anesthetics, Local; Capsaicin; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Isosorbide Dinitrate; Lidocaine; Phenols; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sensory System Agents; Serotonin and Noradrenaline Reuptake Inhibitors; Tapentadol; Tramadol; Transcutaneous Electric Nerve Stimulation; Vasodilator Agents; Venlafaxine Hydrochloride

2016
A Meta-Analysis on the Use of Gabapentinoids for the Treatment of Acute Postoperative Pain Following Total Knee Arthroplasty.
    The Journal of bone and joint surgery. American volume, 2016, Aug-17, Volume: 98, Issue:16

    Topics: Amines; Analgesics; Arthroplasty, Replacement, Knee; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Pain, Postoperative; Pregabalin; Treatment Outcome

2016
The efficacy of preoperative administration of gabapentin/pregabalin in improving pain after total hip arthroplasty: a meta-analysis.
    BMC musculoskeletal disorders, 2016, 08-30, Volume: 17, Issue:1

    Topics: Amines; Analgesics; Arthroplasty, Replacement, Hip; Cyclohexanecarboxylic Acids; Dizziness; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Morphine; Nausea; Pain Management; Pain Measurement; Pain, Postoperative; Pregabalin; Pruritus; Randomized Controlled Trials as Topic; Treatment Outcome; Vomiting

2016
Itch Management: Systemic Agents.
    Current problems in dermatology, 2016, Volume: 50

    Topics: Amines; Analgesics; Analgesics, Opioid; Anion Exchange Resins; Antidepressive Agents; Aprepitant; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Histamine Antagonists; Humans; Morpholines; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Paraneoplastic Syndromes; Peripheral Nervous System Diseases; Pregabalin; Pruritus; Receptors, Opioid, kappa; Receptors, Opioid, mu; Rifampin; Thalidomide; Uremia; Ursodeoxycholic Acid

2016
Neurologic Itch Management.
    Current problems in dermatology, 2016, Volume: 50

    Topics: Acupuncture Therapy; Amines; Anesthetics, Local; Anticonvulsants; Antipruritics; Botulinum Toxins, Type A; Calcineurin Inhibitors; Cannabinoid Receptor Agonists; Capsaicin; Cyclohexanecarboxylic Acids; Doxepin; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuromuscular Agents; Peripheral Nervous System Diseases; Phototherapy; Physical Therapy Modalities; Pregabalin; Pruritus; Tacrolimus; Transcranial Magnetic Stimulation; Transcutaneous Electric Nerve Stimulation

2016
Uremic Itch Management.
    Current problems in dermatology, 2016, Volume: 50

    Topics: Acupuncture Therapy; Amines; Analgesics, Opioid; Anticonvulsants; Calcineurin Inhibitors; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; gamma-Linolenic Acid; Humans; Kidney Failure, Chronic; Morphinans; Narcotic Antagonists; Pregabalin; Pruritus; Receptors, Opioid, kappa; Receptors, Opioid, mu; Renal Dialysis; Spiro Compounds; Tacrolimus; Ultraviolet Therapy; Uremia

2016
Effects of Pregabalin in Patients with Neuropathic Pain Previously Treated with Gabapentin: A Pooled Analysis of Parallel-Group, Randomized, Placebo-controlled Clinical Trials.
    Pain practice : the official journal of World Institute of Pain, 2017, Volume: 17, Issue:6

    Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic; Sleep; Treatment Outcome

2017
Are neuromodulating medications effective for the treatment of chronic neurogenic cough?
    The Laryngoscope, 2017, Volume: 127, Issue:5

    Topics: Amines; Amitriptyline; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents; Practice Guidelines as Topic; Pregabalin

2017
An update of management of insomnia in patients with chronic orofacial pain.
    Oral diseases, 2017, Volume: 23, Issue:8

    Topics: Amines; Anticonvulsants; Antidepressive Agents; Benzodiazepines; Chronic Pain; Cognitive Behavioral Therapy; Cyclohexanecarboxylic Acids; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Melatonin; Orexin Receptor Antagonists; Pregabalin; Sleep Initiation and Maintenance Disorders

2017
Abuse and Misuse of Pregabalin and Gabapentin.
    Drugs, 2017, Volume: 77, Issue:4

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Overdose; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Substance-Related Disorders

2017
An update on the pharmacologic management and treatment of neuropathic pain.
    JAAPA : official journal of the American Academy of Physician Assistants, 2017, Volume: 30, Issue:3

    Topics: Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Cannabinoids; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Medical History Taking; Neuralgia; Pain Management; Physical Examination; Pregabalin; Serotonin and Noradrenaline Reuptake Inhibitors; Transcutaneous Electric Nerve Stimulation

2017
Gabapentinoids for chronic low back pain: a protocol for systematic review and meta-analysis of randomised controlled trials.
    BMJ open, 2016, 11-10, Volume: 6, Issue:11

    Topics: Amines; Chronic Pain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Neuralgia; Pain Management; Pain Measurement; Pregabalin; Randomized Controlled Trials as Topic; Research Design; Systematic Reviews as Topic

2016
Neuropathic pain.
    Nature reviews. Disease primers, 2017, Feb-16, Volume: 3

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Narcotics; Neoplasms; Neuralgia; Nociceptive Pain; Pain Management; Pregabalin; Quality of Life; Tramadol; Transcutaneous Electric Nerve Stimulation; Voltage-Gated Sodium Channel Blockers

2017
The Role of Multimodal Analgesia in Spine Surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2017, Volume: 25, Issue:4

    Topics: Acetaminophen; Amines; Analgesia; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Drug Administration Routes; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Management; Pain, Postoperative; Pregabalin; Spine

2017
Biological rationale and potential clinical use of gabapentin and pregabalin in bipolar disorder, insomnia and anxiety: protocol for a systematic review and meta-analysis.
    BMJ open, 2017, 03-27, Volume: 7, Issue:3

    Topics: Amines; Anti-Anxiety Agents; Anxiety Disorders; Bipolar Disorder; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders; Systematic Reviews as Topic; Treatment Outcome

2017
Advances in the management of diabetic neuropathy.
    Minerva medica, 2017, Volume: 108, Issue:5

    Topics: Adjuvants, Immunologic; Amines; Anticonvulsants; Antidepressive Agents; Antioxidants; Cardiovascular Diseases; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Randomized Controlled Trials as Topic; Thiamine; Thioctic Acid; Treatment Outcome

2017
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
    JAMA surgery, 2017, 07-01, Volume: 152, Issue:7

    Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; N-Methylaspartate; Pain, Postoperative; Postoperative Care; Pregabalin; Tramadol

2017
Treatment of Uremic Pruritus: A Systematic Review.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 70, Issue:5

    Topics: Administration, Cutaneous; Amines; Analgesics; Anti-Asthmatic Agents; Antipruritics; Capsaicin; Cromolyn Sodium; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Phototherapy; Pregabalin; Pruritus; Renal Dialysis; Renal Insufficiency, Chronic; Uremia

2017
Preoperative pregabalin or gabapentin for acute and chronic postoperative pain among patients undergoing breast cancer surgery: A systematic review and meta-analysis of randomized controlled trials.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2017, Volume: 70, Issue:10

    Topics: Amines; Analgesics; Breast Neoplasms; Chronic Pain; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mastectomy; Pain, Postoperative; Perioperative Care; Pregabalin; Randomized Controlled Trials as Topic

2017
Antiepileptic drugs for chronic non-cancer pain in children and adolescents.
    The Cochrane database of systematic reviews, 2017, 08-05, Volume: 8

    Topics: Adolescent; Amines; Amitriptyline; Anticonvulsants; Child; Chronic Pain; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic

2017
Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and meta-analysis of randomized controlled trials.
    PLoS medicine, 2017, Volume: 14, Issue:8

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; England; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Pregabalin; Randomized Controlled Trials as Topic

2017
Gabapentin enacarbil, pregabalin and rotigotine are equally effective in restless legs syndrome: a comparative meta-analysis.
    European journal of neurology, 2017, Volume: 24, Issue:12

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dopamine Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Restless Legs Syndrome; Tetrahydronaphthalenes; Thiophenes; Treatment Outcome

2017
A meta-analysis of the preoperative use of gabapentinoids for the treatment of acute postoperative pain following spinal surgery.
    Medicine, 2017, Volume: 96, Issue:37

    Topics: Acute Pain; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Pregabalin; Randomized Controlled Trials as Topic; Spine

2017
How addictive are gabapentin and pregabalin? A systematic review.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2017, Volume: 27, Issue:12

    Topics: Amines; Analgesics; Behavior, Addictive; Cyclohexanecarboxylic Acids; Databases, Bibliographic; Drug Overdose; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Self Administration; Substance-Related Disorders

2017
WITHDRAWN: Anticonvulsants for fibromyalgia.
    The Cochrane database of systematic reviews, 2017, 10-09, Volume: 10

    Topics: Acetamides; Amines; Anticonvulsants; Conflict of Interest; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Lacosamide; Levetiracetam; Piracetam; Pregabalin

2017
Is there a role for combined use of gabapentin and pregabalin in pain control? Too good to be true?
    Current medical research and opinion, 2018, Volume: 34, Issue:4

    Topics: Analgesics; Drug Therapy, Combination; Gabapentin; Humans; Neuralgia; Pregabalin

2018
Negative myoclonus induced by gabapentin and pregabalin: A case series and systematic literature review.
    Journal of the neurological sciences, 2017, Nov-15, Volume: 382

    Topics: Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Myoclonus; Pregabalin; Prospective Studies; Registries; Retrospective Studies; Young Adult

2017
[On the risk of dependence on gabapentinoids].
    Fortschritte der Neurologie-Psychiatrie, 2018, Volume: 86, Issue:2

    Topics: Analgesics; Behavior, Addictive; Gabapentin; Germany; Humans; Pregabalin; Risk; Substance-Related Disorders

2018
Pharmacotherapy for Neuropathic Pain in Japan.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2017, Volume: 84, Issue:6

    Topics: Aged; Algorithms; Amines; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Japan; Neuralgia; Pain Management; Pregabalin

2017
A critical appraisal of gabapentinoids for pain in cancer patients.
    Current opinion in supportive and palliative care, 2018, Volume: 12, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Cancer Pain; Drug Therapy, Combination; Gabapentin; Humans; Pain; Pain, Postoperative; Palliative Care; Pregabalin; Radiotherapy; Randomized Controlled Trials as Topic; Severity of Illness Index

2018
Use of α2δ Ligands for Restless Legs Syndrome/Willis Ekbom Disease.
    CNS drugs, 2018, Volume: 32, Issue:2

    Topics: Animals; Anticonvulsants; Calcium Channels; Carbamates; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Pregabalin; Restless Legs Syndrome

2018
Gabapentin and pregabalin: do the benefits outweigh the harms?
    The journal of the Royal College of Physicians of Edinburgh, 2017, Volume: 47, Issue:4

    Topics: Chronic Pain; Gabapentin; Humans; Inappropriate Prescribing; Off-Label Use; Pregabalin; Prescription Drug Misuse; Risk Assessment

2017
Analgesic mechanisms of gabapentinoids and effects in experimental pain models: a narrative review.
    British journal of anaesthesia, 2018, Volume: 120, Issue:6

    Topics: Analgesics; Animals; Calcium Channels; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain, Postoperative; Pregabalin

2018
End-Stage Renal Disease Chronic Itch and Its Management.
    Dermatologic clinics, 2018, Volume: 36, Issue:3

    Topics: Amines; Analgesics, Opioid; Anticonvulsants; Antipruritics; Chronic Disease; Cyclohexanecarboxylic Acids; Emollients; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Nalbuphine; Narcotic Antagonists; Pregabalin; Pruritus; Quality of Life; Renal Dialysis; Severity of Illness Index; Ultraviolet Therapy

2018
On the addictive power of gabapentinoids: a mini-review.
    Psychiatria Danubina, 2018, Volume: 30, Issue:2

    Topics: Adult; Amines; Animals; Comorbidity; Craving; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Methadone; Narcotics; Opiate Substitution Treatment; Pregabalin; Reward; Substance Withdrawal Syndrome; Substance-Related Disorders

2018
Non-Hormonal Replacement Therapy Regimens: Do they have an Effect on Cardiovascular Risk?
    Current vascular pharmacology, 2019, Volume: 17, Issue:6

    Topics: Cardiovascular Diseases; Clonidine; Female; Gabapentin; Humans; Menopause; Phytoestrogens; Pregabalin; Risk Assessment; Risk Factors; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Treatment Outcome

2019
Gabapentin or pregabalin induced myoclonus: A case series and literature review.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2019, Volume: 61

    Topics: Adult; Aged; Analgesics; Chronic Pain; Female; Gabapentin; Humans; Male; Middle Aged; Myoclonus; Pregabalin; Renal Dialysis; Renal Insufficiency

2019
Systematic Review of the Efficacy and Safety of Gabapentin and Pregabalin for Pain in Children and Adolescents.
    Anesthesia and analgesia, 2019, Volume: 128, Issue:4

    Topics: Adolescent; Analgesics; Child; Evidence-Based Medicine; Gabapentin; Humans; Pain Management; Pain Measurement; Pain, Postoperative; Patient Safety; Practice Guidelines as Topic; Pregabalin; Randomized Controlled Trials as Topic; Treatment Outcome

2019
The case for cautious consumption: NSAIDs in chronic kidney disease.
    Current opinion in nephrology and hypertension, 2019, Volume: 28, Issue:2

    Topics: Acute Kidney Injury; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Baclofen; Cost-Benefit Analysis; Gabapentin; Humans; Pain; Pregabalin; Renal Insufficiency, Chronic; Tramadol

2019
Gabapentin and pregabalin to treat aggressivity in dementia: a systematic review and illustrative case report.
    British journal of clinical pharmacology, 2019, Volume: 85, Issue:4

    Topics: Aged; Aggression; Alzheimer Disease; Calcium Channel Blockers; Dose-Response Relationship, Drug; Gabapentin; Humans; Male; Pregabalin; Treatment Outcome

2019
Strategies to Treat Chronic Pain and Strengthen Impaired Descending Noradrenergic Inhibitory System.
    International journal of molecular sciences, 2019, Feb-14, Volume: 20, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Chronic Pain; GABA Antagonists; Gabapentin; Humans; Locus Coeruleus; Norepinephrine; Pregabalin; Receptors, Adrenergic, alpha-2; Selective Serotonin Reuptake Inhibitors; Spinal Cord; Spinal Cord Dorsal Horn

2019
A Clinical Overview of Off-label Use of Gabapentinoid Drugs.
    JAMA internal medicine, 2019, 05-01, Volume: 179, Issue:5

    Topics: Analgesics; Diabetic Neuropathies; Drug Approval; Fibromyalgia; Gabapentin; Humans; Low Back Pain; Minimal Clinically Important Difference; Neuralgia; Neuralgia, Postherpetic; Off-Label Use; Pain; Pain Measurement; Pregabalin; Radiculopathy; Sciatica; Spinal Cord Injuries

2019
Pregabalin add-on for drug-resistant focal epilepsy.
    The Cochrane database of systematic reviews, 2019, 07-09, Volume: 7

    Topics: Anticonvulsants; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsies, Partial; Gabapentin; Humans; Lamotrigine; Levetiracetam; Pregabalin; Randomized Controlled Trials as Topic; Seizures

2019
    Proceedings. Mathematical, physical, and engineering sciences, 2019, Volume: 475, Issue:2227

    Topics: Acetylcholine; Acinetobacter baumannii; Actinobacteria; Action Potentials; Adalimumab; Adaptation, Physiological; Adipates; Administration, Oral; Adolescent; Adrenal Glands; Adsorption; Adult; Aged; Aged, 80 and over; Aging; AIDS-Related Opportunistic Infections; Aldosterone; Amino Acids; Ammonia; Amoxicillin; AMP-Activated Protein Kinases; Animals; Antacids; Anti-Bacterial Agents; Antineoplastic Agents; Antirheumatic Agents; Apgar Score; Area Under Curve; ARNTL Transcription Factors; Arterial Pressure; Arthritis, Juvenile; Athletes; Attention; Biodegradation, Environmental; Biofilms; Biofuels; Biological Therapy; Biomass; Biomimetic Materials; Bioreactors; Birth Weight; Bismuth; Blood Flow Velocity; Bone and Bones; Brain Injuries, Traumatic; Calcium; Calcium Channels; Capsaicin; Carbon; Carcinoma, Hepatocellular; Cardiomegaly, Exercise-Induced; Cartilage; Cartilage, Articular; Case-Control Studies; Catalysis; Cats; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Death; Cell Differentiation; Cell Line, Tumor; Cell Membrane; Charcoal; Chemokine CCL2; Child; Child, Preschool; Chondrogenesis; Chronic Disease; Circadian Clocks; Circadian Rhythm Signaling Peptides and Proteins; Clarithromycin; Coccidioides; Coccidioidomycosis; Cognitive Behavioral Therapy; Coinfection; Color; Coloring Agents; Computer Simulation; Computers, Molecular; Consensus; Corticosterone; Cyclic AMP Response Element-Binding Protein; Cytochrome P-450 Enzyme System; Death, Sudden, Cardiac; Density Functional Theory; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Dialysis Solutions; Disease Models, Animal; Dogs; Dopamine Agonists; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Therapy, Combination; Electrocardiography; Electrocardiography, Ambulatory; Electrolytes; Endocardium; Endocrine Disruptors; Endocytosis; Endoscopy, Gastrointestinal; Escherichia coli Proteins; Esters; Evolution, Molecular; Executive Function; Feasibility Studies; Female; Ferric Compounds; Fluorescence; Fluorescent Dyes; Fluorine Radioisotopes; Frailty; Free Radical Scavengers; Gabapentin; Geriatric Assessment; Glucaric Acid; Glucocorticoids; Glucose; Glucose Metabolism Disorders; Halogenated Diphenyl Ethers; Heart Rate; Heart Ventricles; HEK293 Cells; Helicobacter Infections; Helicobacter pylori; Hep G2 Cells; Hepatocytes; Humans; Hungary; Hydrogen Sulfide; Hydrogen-Ion Concentration; Immunologic Factors; Immunomodulation; Immunosuppressive Agents; Independent Living; Indocyanine Green; Infant; Infant Formula; Infant Mortality; Infant, Newborn; Infant, Newborn, Diseases; Inflorescence; Insulin Resistance; Insulins; International Agencies; Iron; Isotonic Solutions; Kidney Failure, Chronic; Kinetics; Lactones; Leukocytes, Mononuclear; Liver Neoplasms; Macular Edema; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetosomes; Male; Medical Audit; Mesenchymal Stem Cells; Metabolic Syndrome; Metformin; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Middle Aged; Molecular Conformation; Molecular Targeted Therapy; Motor Activity; Multiple Sclerosis; Mycophenolic Acid; Netherlands; Neuropsychological Tests; Nuclear Energy; Organs at Risk; Osteoarthritis; Osteoarthritis, Hip; Oxidation-Reduction; Palladium; Pericardium; Perinatal Death; Peritoneal Dialysis; Phantoms, Imaging; Pharmaceutical Preparations; Phospholipids; Phosphorylation; Physical Conditioning, Human; Physical Endurance; Pilot Projects; Polyketides; Polymers; Positron-Emission Tomography; Postoperative Period; Potassium; Powders; Pramipexole; Predictive Value of Tests; Pregabalin; Pregnancy; Pregnancy Outcome; Protein Structure, Secondary; Proton Pump Inhibitors; Puberty; Pulmonary Circulation; Quality Assurance, Health Care; Quantum Dots; Radiometry; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Intensity-Modulated; Rats, Sprague-Dawley; Receptors, CCR2; Receptors, Transferrin; Regeneration; Registries; Renal Insufficiency, Chronic; Reproducibility of Results; Research Design; Restless Legs Syndrome; Retina; Retinoid X Receptor alpha; Retrospective Studies; Rhenium; Risk Factors; RNA, Messenger; Severity of Illness Index; Sex Factors; Sodium; Sodium Fluoride; Solvents; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Stroke; Structure-Activity Relationship; Tachycardia, Ventricular; Tetracycline; Tetrahydrofolate Dehydrogenase; Tetrahydronaphthalenes; Thermodynamics; Thiophenes; Time Factors; Tinidazole; Tomography, Optical Coherence; Tomography, X-Ray Computed; Topiramate; Toxoplasma; Toxoplasmosis, Cerebral; Transferrin; Treatment Outcome; Up-Regulation; Upper Extremity; Uremia; Uveitis; Vascular Remodeling; Ventricular Fibrillation; Ventricular Function, Left; Ventricular Function, Right; Ventricular Remodeling; Verapamil; Veterans; Visual Acuity; Vitrectomy; Water Pollutants, Chemical; Zea mays; Zirconium

2019
[HTA and non-hormonal menopause treatment].
    Presse medicale (Paris, France : 1983), 2019, Volume: 48, Issue:11 Pt 1

    Topics: Acupuncture Therapy; Clonidine; Complementary Therapies; Female; Gabapentin; Hot Flashes; Humans; Hypertension; Menopause; Panax; Phytoestrogens; Pregabalin; Selective Serotonin Reuptake Inhibitors; Vasomotor System

2019
Medicines associated with dependence or withdrawal: a mixed-methods public health review and national database study in England.
    The lancet. Psychiatry, 2019, Volume: 6, Issue:11

    Topics: Acetamides; Adolescent; Adult; Aged; Analgesics; Analgesics, Opioid; Antidepressive Agents; Azabicyclo Compounds; Benzodiazepines; Databases, Factual; England; Female; Gabapentin; Humans; Hypnotics and Sedatives; Male; Middle Aged; Piperazines; Pregabalin; Public Health; Pyrimidines; Substance Withdrawal Syndrome; Substance-Related Disorders; Young Adult; Zolpidem

2019
Update review of pain control methods of tonsil surgery.
    Auris, nasus, larynx, 2020, Volume: 47, Issue:1

    Topics: Adrenal Cortex Hormones; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cryotherapy; Electrocoagulation; Gabapentin; Humans; Hydrocodone; Laser Therapy; Pain, Postoperative; Pregabalin; Radiofrequency Ablation; Tonsillectomy; Tramadol; Ultrasonic Surgical Procedures

2020
Efficacy and safety of gabapentin and pregabalin in patients with vasomotor symptoms: a systematic review and meta-analysis.
    American journal of obstetrics and gynecology, 2020, Volume: 222, Issue:6

    Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Calcium Channel Blockers; Dizziness; Estrogen Replacement Therapy; Excitatory Amino Acid Antagonists; Female; Gabapentin; Hot Flashes; Humans; Menopause; Pregabalin; Quality of Life; Sleepiness; Treatment Outcome; Vasomotor System

2020
Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?
    Epilepsia, 2020, Volume: 61, Issue:3

    Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Atorvastatin; Brain Injuries, Traumatic; Ceftriaxone; Dibenzazepines; Drug Repositioning; Epilepsy; Epilepsy, Post-Traumatic; Erythropoietin; Fingolimod Hydrochloride; GABA Agents; Gabapentin; Humans; Immunologic Factors; Inflammation; Interleukin 1 Receptor Antagonist Protein; Isoflurane; Levetiracetam; Losartan; Neuroprotective Agents; Oxidative Stress; Pregabalin; Pyrrolidinones; Sirolimus; Stroke; Topiramate; Translational Research, Biomedical; Vigabatrin

2020
Analgesia with Gabapentin and Pregabalin May Involve
    The Journal of pharmacology and experimental therapeutics, 2020, Volume: 374, Issue:1

    Topics: Analgesics; Animals; Calcium Channels; Gabapentin; Humans; Pregabalin; Receptors, N-Methyl-D-Aspartate; Thrombospondins

2020
Pregabalin and gabapentin for pain.
    BMJ (Clinical research ed.), 2020, Apr-28, Volume: 369

    Topics: Analgesics; Diabetic Neuropathies; Evidence-Based Medicine; Fibromyalgia; Gabapentin; Humans; Neuralgia; Neuralgia, Postherpetic; Pregabalin

2020
Perioperative Analgesia for Patients Undergoing Thyroidectomy and Parathyroidectomy: An Evidence-Based Review.
    The Annals of otology, rhinology, and laryngology, 2020, Volume: 129, Issue:10

    Topics: Acetaminophen; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Evidence-Based Medicine; Gabapentin; Humans; Ketamine; Pain Management; Pain, Postoperative; Parathyroidectomy; Perioperative Care; Postoperative Nausea and Vomiting; Pregabalin; Thyroidectomy

2020
Post-Burn Pruritus.
    International journal of molecular sciences, 2020, May-29, Volume: 21, Issue:11

    Topics: Animals; Antipsychotic Agents; Burns; Gabapentin; Histamine Antagonists; Humans; Inflammation; Keratinocytes; Narcotic Antagonists; Neuropeptides; Ondansetron; Pregabalin; Pruritus; Receptors, Opioid; Wound Healing

2020
Beneficial "Pharmaceutical Pleiotropy" of Gabapentinoids in Spinal Cord Injury: A Case for Refining Standard-of-Care.
    Neurorehabilitation and neural repair, 2020, Volume: 34, Issue:8

    Topics: Analgesics; Animals; Gabapentin; Humans; Neuralgia; Pregabalin; Spinal Cord Injuries

2020
The Efficacy and Safety of Gabapentinoids in Total Joint Arthroplasty: Systematic Review and Direct Meta-Analysis.
    The Journal of arthroplasty, 2020, Volume: 35, Issue:10

    Topics: Analgesics; Analgesics, Opioid; Arthroplasty; Gabapentin; Humans; Pain, Postoperative; Pregabalin

2020
Gabapentinoids for treatment of alcohol use disorder: A systematic review and meta-analysis.
    Human psychopharmacology, 2020, Volume: 35, Issue:6

    Topics: Alcohol Drinking; Alcoholism; Craving; Gabapentin; Humans; Pregabalin; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome

2020
Use of anticonvulsants and antidepressants for treatment of complex regional pain syndrome: a literature review.
    Pain management, 2021, Volume: 11, Issue:2

    Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents; Complex Regional Pain Syndromes; Gabapentin; Humans; Pregabalin

2021
Abuse and Misuse of Pregabalin and Gabapentin: A Systematic Review Update.
    Drugs, 2021, Volume: 81, Issue:1

    Topics: Animals; Drug Overdose; Gabapentin; Humans; Pregabalin

2021
Bioequivalence and switchability of generic antiseizure medications (ASMs): A re-appraisal based on analysis of generic ASM products approved in Europe.
    Epilepsia, 2021, Volume: 62, Issue:2

    Topics: Anticonvulsants; Area Under Curve; Biological Variation, Individual; Dibenzazepines; Drug Substitution; Drugs, Generic; Europe; Gabapentin; Humans; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Pregabalin; Therapeutic Equivalency; Topiramate; Vigabatrin; Zonisamide

2021
Is there evidence for using anticonvulsants in the prevention and/or treatment of delirium among older adults?
    International psychogeriatrics, 2022, Volume: 34, Issue:10

    Topics: Aged; Anticonvulsants; Arthroplasty, Replacement, Hip; Delirium; Gabapentin; Humans; Pregabalin

2022
Derivatization of γ-Amino Butyric Acid Analogues for Their Determination in the Biological Samples and Pharmaceutical Preparations: A Comprehensive Review.
    Critical reviews in analytical chemistry, 2022, Volume: 52, Issue:8

    Topics: Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Pharmaceutical Preparations; Pregabalin; Vigabatrin

2022
The gabapentinoid drugs and their abuse potential.
    Pharmacology & therapeutics, 2021, Volume: 227

    Topics: Analgesics; Chronic Pain; Gabapentin; Humans; Pregabalin; Substance-Related Disorders

2021
HIV Neuropathy-a Review of Mechanisms, Diagnosis, and Treatment of Pain.
    Current pain and headache reports, 2021, Jul-08, Volume: 25, Issue:8

    Topics: Anesthetics, Local; Gabapentin; HIV Infections; Humans; Neuralgia; Neurologic Examination; Pregabalin

2021
Gabapentinoid Pharmacology in the Context of Emerging Misuse Liability.
    Journal of clinical pharmacology, 2021, Volume: 61 Suppl 2

    Topics: Area Under Curve; Calcium Channel Blockers; Drug Overdose; Gabapentin; Half-Life; Humans; Metabolic Clearance Rate; Pregabalin; Prescription Drug Misuse; Respiratory Insufficiency; Substance Withdrawal Syndrome; Substance-Related Disorders; United States

2021
Management of diabetic neuropathy.
    Metabolism: clinical and experimental, 2021, Volume: 123

    Topics: Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; Humans; Life Style; Pain Management; Pregabalin; Risk Factors; Weight Loss

2021
Lesser Known Uses of γ-Aminobutyric Acid Analogue Medications in Otolaryngology.
    The Laryngoscope, 2022, Volume: 132, Issue:5

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Otolaryngology; Pregabalin; Trismus

2022
A systematic review and meta-analysis of the effectiveness and adverse events of gabapentin and pregabalin for sciatica pain.
    Atencion primaria, 2022, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Analgesics; Gabapentin; Humans; Low Back Pain; Pregabalin; Sciatica

2022
Extracorporeal Treatment for Gabapentin and Pregabalin Poisoning: Systematic Review and Recommendations From the EXTRIP Workgroup.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2022, Volume: 79, Issue:1

    Topics: Drug Overdose; Frailty; Gabapentin; Humans; Poisoning; Pregabalin; Renal Dialysis

2022
Gabapentin and pregabalin in bipolar disorder, anxiety states, and insomnia: Systematic review, meta-analysis, and rationale.
    Molecular psychiatry, 2022, Volume: 27, Issue:3

    Topics: Amines; Anxiety; Bipolar Disorder; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders

2022
Quality of meta-analyses of non-opioid, pharmacological, perioperative interventions for chronic postsurgical pain: a systematic review.
    Regional anesthesia and pain medicine, 2022, Volume: 47, Issue:4

    Topics: Adult; Chronic Pain; Gabapentin; Humans; Ketamine; Pain, Postoperative; Pregabalin

2022
Gabapentinoid Use in Perioperative Care and Current Controversies.
    Current pain and headache reports, 2022, Volume: 26, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Gabapentin; Humans; Pain, Postoperative; Perioperative Care; Pregabalin

2022
Pharmacological management of fibromyalgia: a Bayesian network meta-analysis.
    Expert review of clinical pharmacology, 2022, Volume: 15, Issue:2

    Topics: Analgesics; Duloxetine Hydrochloride; Fibromyalgia; Gabapentin; Humans; Network Meta-Analysis; Pregabalin

2022
Different interventions for preventing postoperative catheter-related bladder discomfort: a systematic review and meta-analysis.
    European journal of clinical pharmacology, 2022, Volume: 78, Issue:6

    Topics: Chlorpheniramine; Dexmedetomidine; Gabapentin; Haloperidol; Humans; Ketamine; Lidocaine; Meperidine; Nefopam; Pain, Postoperative; Pregabalin; Tolterodine Tartrate; Tramadol; Urinary Bladder; Urinary Catheters

2022
[Pharmacological approach to neuropathic pain: past, present and future].
    Revista de neurologia, 2022, 04-16, Volume: 74, Issue:8

    Topics: Amitriptyline; Analgesics; Animals; Antidepressive Agents, Tricyclic; Gabapentin; Humans; Neuralgia; Pregabalin

2022
Analgesic Efficacy of Gabapentin and Pregabalin in Patients Undergoing Laparoscopic Bariatric Surgeries: a Systematic Review and Meta-analysis.
    Obesity surgery, 2022, Volume: 32, Issue:8

    Topics: Analgesics; Bariatric Surgery; Gabapentin; Humans; Laparoscopy; Nausea; Obesity, Morbid; Pain, Postoperative; Pregabalin; Vomiting

2022
Evidence-Based Treatment of Painful Diabetic Neuropathy: a Systematic Review.
    Current pain and headache reports, 2022, Volume: 26, Issue:8

    Topics: Diabetes Mellitus; Diabetic Neuropathies; Gabapentin; Humans; Insulins; Pregabalin; Spinal Cord Stimulation

2022
Pharmacotherapy for Spine-Related Pain in Older Adults.
    Drugs & aging, 2022, Volume: 39, Issue:7

    Topics: Acetaminophen; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Gabapentin; Humans; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Tramadol

2022
Pharmacologic therapies of pain in patients with spinal cord injury: a systematic review.
    Spinal cord series and cases, 2022, 07-04, Volume: 8, Issue:1

    Topics: Amitriptyline; Anticonvulsants; Gabapentin; Humans; Ketamine; Pain; Pregabalin; Spinal Cord Injuries

2022
Effects of Gabapentin and Pregabalin on Calcium Homeostasis: Implications for Physical Rehabilitation of Musculoskeletal Tissues.
    Current osteoporosis reports, 2022, Volume: 20, Issue:6

    Topics: Calcium; Gabapentin; gamma-Aminobutyric Acid; Homeostasis; Humans; Pregabalin

2022
Avellis syndrome with ipsilateral prosopalgia, glossopharyngeal neuralgia, and central post-stroke pain: A case report and literature review.
    Medicine, 2022, Sep-30, Volume: 101, Issue:39

    Topics: Aspirin; Carbamazepine; Deglutition Disorders; Dizziness; Female; Gabapentin; Glossopharyngeal Nerve Diseases; Horner Syndrome; Humans; Infarction; Lipids; Middle Aged; Neuralgia; Pregabalin; Rosuvastatin Calcium; Sodium Chloride; Tablets; Trigeminal Neuralgia

2022
Efficacy and safety of different antidepressants and anticonvulsants in central poststroke pain: A network meta-analysis and systematic review.
    PloS one, 2022, Volume: 17, Issue:10

    Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents; Carbamazepine; Duloxetine Hydrochloride; Fluoxetine; Gabapentin; Humans; Lamotrigine; Multicenter Studies as Topic; Network Meta-Analysis; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic; Vitamins

2022
Treatment modalities in brachioradial pruritis: a systematic review.
    Dermatology online journal, 2022, Aug-15, Volume: 28, Issue:4

    Topics: Antidepressive Agents, Tricyclic; Capsaicin; Gabapentin; Humans; Pregabalin; Pruritus; Quality of Life; Randomized Controlled Trials as Topic

2022
[Drug abuse of pregabalin - state of the situation, risks and means of control].
    Annales pharmaceutiques francaises, 2023, Volume: 81, Issue:3

    Topics: Anticonvulsants; Drug Overdose; Gabapentin; Humans; Pregabalin; Substance-Related Disorders

2023
Little evidence supports gabapentinoid use in bipolar disorder or insomnia.
    BMJ (Clinical research ed.), 2022, 11-18, Volume: 379

    Topics: Bipolar Disorder; Gabapentin; Humans; Pregabalin; Sleep Initiation and Maintenance Disorders

2022
Perioperative Indications for Gabapentinoids in Pediatrics: A Narrative Review.
    Paediatric drugs, 2023, Volume: 25, Issue:1

    Topics: Analgesics; Child; Gabapentin; Humans; Pain, Postoperative; Pregabalin

2023
Gabapentinoids for Pain: A Review of Published Comparative Effectiveness Trials and Data Submitted to the FDA for Approval.
    Drugs, 2023, Volume: 83, Issue:1

    Topics: Analgesics; Gabapentin; Humans; Pain; Pregabalin; United States; United States Food and Drug Administration

2023
Gabapentin-Induced Overflow Urinary Incontinence: A Case Report and Review of the Literature.
    Journal of pain & palliative care pharmacotherapy, 2023, Volume: 37, Issue:2

    Topics: Amines; Analgesics; Carcinoma, Non-Small-Cell Lung; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lung Neoplasms; Male; Middle Aged; Neuralgia; Pregabalin; Urinary Incontinence

2023
Perioperative Gabapentin May Reduce Opioid Requirement for Early Postoperative Pain in Patients Undergoing Anterior Cruciate Ligament Reconstruction: A Systematic Review of Randomized Controlled Trials.
    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 2023, Volume: 39, Issue:7

    Topics: Analgesics; Analgesics, Opioid; Anterior Cruciate Ligament Reconstruction; Gabapentin; Humans; Pain, Postoperative; Pregabalin; Randomized Controlled Trials as Topic

2023
The safety and efficacy of gabapentinoids in the management of neuropathic pain: a systematic review with meta-analysis of randomised controlled trials.
    International journal of clinical pharmacy, 2023, Volume: 45, Issue:3

    Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic

2023
Non-opioid antinociceptive drugs : risk of respiratory depression and death related to concomitant use of gabapentinoids in addition to opioids.
    Expert opinion on drug safety, 2023, Volume: 22, Issue:3

    Topics: Analgesics, Opioid; Cross-Sectional Studies; Gabapentin; Humans; Pregabalin; Respiratory Insufficiency

2023
Restless Legs Syndrome in Chronic Kidney Disease- a Systematic Review.
    Tremor and other hyperkinetic movements (New York, N.Y.), 2023, Volume: 13

    Topics: Child; Dopamine Agents; Gabapentin; Humans; Iron; Pregabalin; Quality of Life; Renal Insufficiency, Chronic; Restless Legs Syndrome

2023
The effect of gabapentin and pregabalin administration on memory in clinical and preclinical studies: a meta-analysis and systematic review.
    BMC psychiatry, 2023, 04-17, Volume: 23, Issue:1

    Topics: Analgesics; Animals; Gabapentin; Pregabalin

2023
Pregabalin and gabapentin for chronic low back pain without radiculopathy: a systematic review.
    Arquivos de neuro-psiquiatria, 2023, Volume: 81, Issue:6

    Topics: Celecoxib; Gabapentin; Humans; Low Back Pain; Pregabalin; Radiculopathy

2023
A Brief Review on the Novel Therapies for Painful Diabetic Neuropathy.
    Current pain and headache reports, 2023, Volume: 27, Issue:9

    Topics: Diabetes Mellitus; Diabetic Neuropathies; Endocannabinoids; Gabapentin; Humans; Pregabalin; Quality of Life

2023
Therapeutic Strategies for Postherpetic Neuralgia: Mechanisms, Treatments, and Perspectives.
    Current pain and headache reports, 2023, Volume: 27, Issue:9

    Topics: Aged; Analgesics; Antidepressive Agents, Tricyclic; Gabapentin; Humans; Lidocaine; Neuralgia, Postherpetic; Pregabalin

2023
Different Gabapentin and Pregabalin Dosages for Perioperative Pain Control in Patients Undergoing Spine Surgery: A Systematic Review and Network Meta-Analysis.
    JAMA network open, 2023, 08-01, Volume: 6, Issue:8

    Topics: Analgesics; Analgesics, Opioid; Female; Gabapentin; Humans; Middle Aged; Network Meta-Analysis; Pain, Postoperative; Pregabalin

2023

Trials

31 trial(s) available for gabapentin and pregabalin

ArticleYear
Myoclonus in epilepsy patients with anticonvulsive add-on therapy with pregabalin.
    Epilepsia, 2001, Volume: 42, Issue:6

    Topics: Acetates; Adult; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Electroencephalography; Electromyography; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Humans; Incidence; Male; Myoclonus; Pregabalin; Randomized Controlled Trials as Topic

2001
Pregabalin exerts oppositional effects on different inhibitory circuits in human motor cortex: a double-blind, placebo-controlled transcranial magnetic stimulation study.
    Epilepsia, 2006, Volume: 47, Issue:5

    Topics: Adult; Amines; Anticonvulsants; Calcium Channels; Cyclohexanecarboxylic Acids; Double-Blind Method; Evoked Potentials, Motor; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Motor Cortex; Neural Inhibition; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Placebos; Pregabalin; Receptors, GABA-B; Recruitment, Neurophysiological; Tiagabine; Transcranial Magnetic Stimulation

2006
Cost-effectiveness analysis of pregabalin versus gabapentin in the management of neuropathic pain due to diabetic polyneuropathy or post-herpetic neuralgia.
    Current medical research and opinion, 2007, Volume: 23, Issue:10

    Topics: Amines; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Pain; Pain Measurement; Placebos; Pregabalin

2007
Duloxetine, pregabalin, and duloxetine plus gabapentin for diabetic peripheral neuropathic pain management in patients with inadequate pain response to gabapentin: an open-label, randomized, noninferiority comparison.
    Mayo Clinic proceedings, 2011, Volume: 86, Issue:7

    Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Pregabalin; Thiophenes; Treatment Outcome

2011
A comparative efficacy of amitriptyline, gabapentin, and pregabalin in neuropathic cancer pain: a prospective randomized double-blind placebo-controlled study.
    The American journal of hospice & palliative care, 2012, Volume: 29, Issue:3

    Topics: Adult; Amines; Amitriptyline; Analgesics; Analysis of Variance; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Morphine; Neoplasms; Neuralgia; Pain Measurement; Pregabalin; Prospective Studies

2012
Costs and health resources utilization following switching to pregabalin in individuals with gabapentin-refractory neuropathic pain: a post hoc analysis.
    Pain practice : the official journal of World Institute of Pain, 2012, Volume: 12, Issue:5

    Topics: Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Health Care Costs; Health Resources; Humans; Male; Middle Aged; Neuralgia; Pregabalin; Spain

2012
Perioperative administration of gabapentin 1,200 mg day-1 and pregabalin 300 mg day-1 for pain following lumbar laminectomy and discectomy: a randomised, double-blinded, placebo-controlled study.
    Singapore medical journal, 2011, Volume: 52, Issue:12

    Topics: Adult; Aged; Amines; Analgesics; Anesthesiology; Cyclohexanecarboxylic Acids; Diskectomy; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Laminectomy; Lumbar Vertebrae; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Placebos; Pregabalin

2011
Pregabalin and gabapentin for post-photorefractive keratectomy pain: a randomized controlled trial.
    European journal of ophthalmology, 2012, Volume: 22 Suppl 7

    Topics: Acetaminophen; Administration, Oral; Adult; Amines; Analgesics; Codeine; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Eye Pain; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain Measurement; Pain, Postoperative; Photorefractive Keratectomy; Pregabalin; Prospective Studies; Treatment Outcome; Young Adult

2012
Gabapentin versus pregabalin in improving sleep quality and depression in hemodialysis patients with peripheral neuropathy: a randomized prospective crossover trial.
    International urology and nephrology, 2013, Volume: 45, Issue:3

    Topics: Amines; Anti-Anxiety Agents; Calcium Channel Blockers; Cross-Over Studies; Cyclohexanecarboxylic Acids; Depression; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Male; Middle Aged; Peripheral Nervous System Diseases; Pregabalin; Prospective Studies; Quality of Life; Renal Dialysis; Sleep; Sleep Wake Disorders; Surveys and Questionnaires; Treatment Outcome

2013
Pregabalin versus gabapentin in the treatment of neuropathic pruritus in maintenance haemodialysis patients: a prospective, crossover study.
    Nephrology (Carlton, Vic.), 2012, Volume: 17, Issue:8

    Topics: Adult; Aged; Amines; Analgesics; Antipruritics; Chi-Square Distribution; Cross-Over Studies; Cyclohexanecarboxylic Acids; Electromyography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Pregabalin; Prospective Studies; Pruritus; Renal Dialysis; Surveys and Questionnaires; Time Factors; Treatment Outcome; Turkey

2012
Uraemic pruritus: relief of itching by gabapentin and pregabalin.
    Nephron. Clinical practice, 2012, Volume: 122, Issue:3-4

    Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Comorbidity; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pregabalin; Prevalence; Pruritus; Renal Insufficiency, Chronic; Risk Factors; Treatment Outcome; United Kingdom; Uremia

2012
Cross-over, open-label trial of the effects of gabapentin versus pregabalin on painful peripheral neuropathy and health-related quality of life in haemodialysis patients.
    Clinical drug investigation, 2013, Volume: 33, Issue:6

    Topics: Adult; Aged; Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Peripheral Nervous System Diseases; Pregabalin; Prospective Studies; Quality of Life; Renal Dialysis; Surveys and Questionnaires; Treatment Outcome

2013
Duloxetine Compared with Pregabalin for Diabetic Peripheral Neuropathic Pain Management in Patients with Suboptimal Pain Response to Gabapentin and Treated with or without Antidepressants: A Post Hoc Analysis.
    Pain practice : the official journal of World Institute of Pain, 2014, Volume: 14, Issue:7

    Topics: Adult; Aged; Amines; Analgesics; Antidepressive Agents; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Management; Pain Measurement; Pregabalin; Treatment Outcome

2014
Postoperative pain and long-term functional outcome after administration of gabapentin and pregabalin in patients undergoing spinal surgery.
    Spine, 2014, Mar-15, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Disability Evaluation; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; India; Male; Middle Aged; Orthopedic Procedures; Pain Measurement; Pain, Postoperative; Pregabalin; Prospective Studies; Quality of Life; Recovery of Function; Spine; Surveys and Questionnaires; Time Factors; Young Adult

2014
Clinical study evaluating pregabalin efficacy and tolerability for pain management in patients undergoing laparoscopic cholecystectomy.
    The Clinical journal of pain, 2014, Volume: 30, Issue:11

    Topics: Adult; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, Laparoscopic; Cyclohexanecarboxylic Acids; Diclofenac; Dizziness; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Meperidine; Middle Aged; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Postoperative Nausea and Vomiting; Pregabalin; Prospective Studies; Young Adult

2014
Comparative safety and tolerability of duloxetine vs. pregabalin vs. duloxetine plus gabapentin in patients with diabetic peripheral neuropathic pain.
    International journal of clinical practice, 2014, Volume: 68, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Peripheral Nervous System Diseases; Pregabalin; Treatment Outcome

2014
Gabapentin versus pregabalin in relieving early post-surgical neuropathic pain in patients after lumbar disc herniation surgery: a prospective clinical trial.
    Neurological research, 2014, Volume: 36, Issue:12

    Topics: Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diskectomy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Neuralgia; Pain Measurement; Pregabalin; Prospective Studies; Treatment Outcome

2014
Can pregabalin prevent paclitaxel-associated neuropathy?--An ACCRU pilot trial.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016, Volume: 24, Issue:2

    Topics: Acute Pain; Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypesthesia; Male; Middle Aged; Neoplasms; Paclitaxel; Paresthesia; Peripheral Nervous System Diseases; Pilot Projects; Placebos; Pregabalin; Quality of Life; Surveys and Questionnaires

2016
Clinical Trial Assessing the Efficacy of Gabapentin Plus B Complex (B1/B12) versus Pregabalin for Treating Painful Diabetic Neuropathy.
    Journal of diabetes research, 2016, Volume: 2016

    Topics: Adolescent; Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Combinations; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Pregabalin; Thiamine; Visual Analog Scale; Vitamin B 12

2016
A Validated Fluorometric Method for the Rapid Determination of Pregabalin in Human Plasma Applied to Patients With Pain.
    Therapeutic drug monitoring, 2016, Volume: 38, Issue:5

    Topics: Amines; Analgesics; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Data Accuracy; Fluorometry; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Pain; Pregabalin; Reference Standards

2016
Adjunctive pregabalin vs gabapentin for focal seizures: Interpretation of comparative outcomes.
    Neurology, 2016, Sep-20, Volume: 87, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pregabalin; Seizures; Treatment Outcome; Young Adult

2016
The Effectiveness of Oral Corticosteroids for Management of Lumbar Radiating Pain: Randomized, Controlled Trial Study.
    Clinics in orthopedic surgery, 2016, Volume: 8, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Lumbosacral Region; Male; Middle Aged; Patient Satisfaction; Pregabalin; Quality of Life; Radiculopathy; Surveys and Questionnaires; Young Adult

2016
Efficacy and safety of oxycodone/naloxone as add-on therapy to gabapentin or pregabalin for the management of chemotherapy-induced peripheral neuropathy in Korea.
    Asia-Pacific journal of clinical oncology, 2018, Volume: 14, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Antineoplastic Agents; Female; Gabapentin; Humans; Male; Middle Aged; Naloxone; Neuralgia; Oxycodone; Pain Management; Peripheral Nervous System Diseases; Pregabalin; Republic of Korea

2018
Pregabalin versus gabapentin in the treatment of sciatica: study protocol for a randomised, double-blind, cross-over trial (PAGPROS).
    Trials, 2018, Jan-09, Volume: 19, Issue:1

    Topics: Cross-Over Studies; Data Collection; Double-Blind Method; Gabapentin; Humans; Pregabalin; Prospective Studies; Randomized Controlled Trials as Topic; Sample Size; Sciatica

2018
Effects of gabapentin, pregabalin and gastroretentive gabapentin on simulated driving, daytime sedation and cognition.
    Pain management, 2018, Jul-01, Volume: 8, Issue:4

    Topics: Adult; Amines; Analgesics; Attention; Automobile Driving; Cognition; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Healthy Volunteers; Humans; Learning; Male; Pregabalin; Psychomotor Performance; Tremor; Wakefulness

2018
Effects of Gabapentinoids Premedication on Shoulder Pain and Rehabilitation Quality after Laparoscopic Cholecystectomy: Pregabalin versus Gabapentin.
    Pain research & management, 2018, Volume: 2018

    Topics: Adult; Analgesics; Cholecystectomy; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain, Postoperative; Pregabalin; Shoulder Pain; Treatment Outcome

2018
Effect of Gabapentin vs Pregabalin on Pain Intensity in Adults With Chronic Sciatica: A Randomized Clinical Trial.
    JAMA neurology, 2019, 01-01, Volume: 76, Issue:1

    Topics: Adult; Aged; Analgesics; Chronic Pain; Cross-Over Studies; Double-Blind Method; Female; Gabapentin; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Pregabalin; Sciatica

2019
The Clinical Difference between Gabapentin and Pregabalin: Data from a Pilot Comparative Trial.
    Reviews on recent clinical trials, 2021, Volume: 16, Issue:3

    Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pilot Projects; Pregabalin

2021
Influence of pregabalin maintenance on cannabis effects and related behaviors in daily cannabis users.
    Experimental and clinical psychopharmacology, 2022, Volume: 30, Issue:5

    Topics: Calcium Channels, L-Type; Cannabinoid Receptor Agonists; Cannabinoids; Cannabis; Double-Blind Method; Dronabinol; Female; Gabapentin; Hallucinogens; Humans; Ligands; Male; Marijuana Abuse; Pregabalin

2022
A comparison of the preemptive effects of oral pregabalin and gabapentin on acute postoperative sedation and complications in patients undergoing lumbar spine surgery.
    Journal of perioperative practice, 2023, Volume: 33, Issue:11

    Topics: Analgesics; Anesthesia, General; Female; Gabapentin; Humans; Hypnotics and Sedatives; Male; Pain, Postoperative; Pregabalin; Prospective Studies

2023
Efficacy and Safety of Anxiolytics in Mohs Micrographic Surgery: A Randomized, Double-Blinded, Placebo-Controlled Trial.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2023, 11-01, Volume: 49, Issue:11

    Topics: Alprazolam; Anti-Anxiety Agents; Anxiety; Diazepam; Double-Blind Method; Gabapentin; Humans; Lorazepam; Melatonin; Mohs Surgery; Pregabalin

2023

Other Studies

277 other study(ies) available for gabapentin and pregabalin

ArticleYear
Effect of gabapentin derivates on mechanical allodynia-like behaviour in a rat model of chronic sciatic constriction injury.
    Bioorganic & medicinal chemistry letters, 2004, May-17, Volume: 14, Issue:10

    Topics: Amines; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Cyclohexanols; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Memantine; Pain; Pain Threshold; Pregabalin; Prodrugs; Rats; Sciatic Neuropathy; Structure-Activity Relationship; Venlafaxine Hydrochloride

2004
Structure-activity relationships of pregabalin and analogues that target the alpha(2)-delta protein.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Amines; Amino Acid Transport System L; Analgesics; Animals; Anti-Anxiety Agents; Anticonvulsants; Brain; Calcium Channels; CHO Cells; Cricetinae; Cricetulus; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Leucine; Male; Mice; Mice, Inbred DBA; Pregabalin; Protein Binding; Protein Subunits; Rats; Structure-Activity Relationship; Swine

2005
Oxadiazolone bioisosteres of pregabalin and gabapentin.
    Bioorganic & medicinal chemistry letters, 2009, Jan-01, Volume: 19, Issue:1

    Topics: Amines; Animals; Brain; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Octamer Transcription Factors; Organic Anion Transporters; Osteoarthritis; Oxadiazoles; Pregabalin; Rats

2009
Synthesis and in vivo evaluation of 3-substituted gababutins.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: Amines; Amino Acids; Animals; Anti-Anxiety Agents; Calcium Channels; Carrageenan; Cyclohexanecarboxylic Acids; Cyclopentanes; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Rats; Stereoisomerism

2010
Synthesis and in vivo evaluation of 3,4-disubstituted gababutins.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: Amines; Amino Acids; Animals; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Cyclopentanes; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Rats

2010
Synthesis, characterization and in vitro pharmacology of novel pregabalin derivatives.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Animals; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Pregabalin; Rats; Spectrophotometry, Infrared

2010
Part 3: Design and synthesis of proline-derived α2δ ligands.
    Bioorganic & medicinal chemistry letters, 2011, Jun-15, Volume: 21, Issue:12

    Topics: Animals; Drug Design; Humans; Inhibitory Concentration 50; Ligands; Molecular Structure; Pain; Proline; Rats; Swine

2011
Part 2: Design, synthesis and evaluation of hydroxyproline-derived α2δ ligands.
    Bioorganic & medicinal chemistry letters, 2011, Jun-15, Volume: 21, Issue:12

    Topics: Amines; Animals; Cells, Cultured; Cyclohexanecarboxylic Acids; Dogs; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydroxyproline; Ligands; Molecular Structure; Protein Subunits; Rats

2011
Part 1: N-alkylated glycines as potent α2δ ligands.
    Bioorganic & medicinal chemistry letters, 2011, Jun-15, Volume: 21, Issue:12

    Topics: Alkylation; Calcium Channels; Glycine; Inhibitory Concentration 50; Ligands; Molecular Structure; Protein Subunits; Structure-Activity Relationship

2011
Aminopiperidine sulfonamide Cav2.2 channel inhibitors for the treatment of chronic pain.
    Journal of medicinal chemistry, 2012, Nov-26, Volume: 55, Issue:22

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Cells, Cultured; Chronic Pain; Dogs; Humans; Hyperalgesia; Inflammation; Mice; Mice, Knockout; Microsomes, Liver; Neuralgia; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Sulfonamides; Tissue Distribution

2012
Potent and stereospecific anticonvulsant activity of 3-isobutyl GABA relates to in vitro binding at a novel site labeled by tritiated gabapentin.
    Epilepsy research, 1993, Volume: 14, Issue:1

    Topics: Acetates; Amines; Animals; Anticonvulsants; Binding, Competitive; Cerebral Cortex; Cyclohexanecarboxylic Acids; Electroshock; Gabapentin; gamma-Aminobutyric Acid; Injections, Intravenous; Male; Mice; Pregabalin; Receptors, GABA-A; Stereoisomerism; Synaptic Membranes

1993
Gabapentin (neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents.
    British journal of pharmacology, 1997, Volume: 121, Issue:8

    Topics: Acetates; Amines; Analgesics; Animals; Calcium Channel Blockers; Calcium Channels; Cyclohexanecarboxylic Acids; Discrimination Learning; Drug Tolerance; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Motility; Hyperalgesia; Male; Morphine; Naloxone; Pregabalin; Rats; Rats, Sprague-Dawley; Stereoisomerism

1997
Evaluation of gabapentin and S-(+)-3-isobutylgaba in a rat model of postoperative pain.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:3

    Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Morphine; Pain, Postoperative; Pregabalin; Rats; Rats, Sprague-Dawley

1997
The effect of intrathecal gabapentin and 3-isobutyl gamma-aminobutyric acid on the hyperalgesia observed after thermal injury in the rat.
    Anesthesia and analgesia, 1998, Volume: 86, Issue:2

    Topics: Acetates; Amines; Animals; Anticonvulsants; Burns; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Spinal; Male; Pain; Pregabalin; Rats; Rats, Sprague-Dawley; Reflex; Serine; Stereoisomerism; Structure-Activity Relationship

1998
Attenuation of formalin-induced nociceptive behaviors following local peripheral injection of gabapentin.
    Pain, 1998, Volume: 76, Issue:1-2

    Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Injections, Subcutaneous; Male; Nociceptors; Pain; Pain Measurement; Pregabalin; Rats; Rats, Sprague-Dawley; Serine

1998
Systemic gabapentin and S(+)-3-isobutyl-gamma-aminobutyric acid block secondary hyperalgesia.
    Brain research, 1998, Nov-09, Volume: 810, Issue:1-2

    Topics: Acetates; Amines; Animals; Anticonvulsants; Burns; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Intraperitoneal; Male; Pain Threshold; Pregabalin; Rats; Rats, Sprague-Dawley

1998
Gabapentin and pregabalin, but not morphine and amitriptyline, block both static and dynamic components of mechanical allodynia induced by streptozocin in the rat.
    Pain, 1999, Volume: 80, Issue:1-2

    Topics: Acetates; Amines; Amitriptyline; Analgesics; Animals; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperglycemia; Injections; Injections, Spinal; Male; Morphine; Pain; Physical Stimulation; Pregabalin; Rats; Rats, Sprague-Dawley; Skin; Streptozocin; Touch

1999
Transport of pregabalin in rat intestine and Caco-2 monolayers.
    Pharmaceutical research, 1999, Volume: 16, Issue:4

    Topics: Acetates; Amines; Amino Acids; Animals; Anticonvulsants; Biological Transport; Caco-2 Cells; Colon; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ileum; In Vitro Techniques; Intestinal Mucosa; Male; Mannitol; Phenylalanine; Pregabalin; Rats; Rats, Sprague-Dawley

1999
Inhibition of K(+)-evoked glutamate release from rat neocortical and hippocampal slices by gabapentin.
    Neuroscience letters, 2000, Feb-18, Volume: 280, Issue:2

    Topics: Acetates; Agatoxins; Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Neocortex; omega-Conotoxins; Potassium; Pregabalin; Rats; Rats, Sprague-Dawley; Spider Venoms

2000
The effects of gabapentin in the rat hippocampus are mimicked by two structural analogs, but not by nimodipine.
    Epilepsy research, 2000, Volume: 41, Issue:2

    Topics: Acetates; Amines; Animals; Anticonvulsants; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Cyclohexanes; Dentate Gyrus; Diazepam; Dose-Response Relationship, Drug; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Male; Neural Inhibition; Nimodipine; Pregabalin; Rats; Rats, Sprague-Dawley; Reaction Time; Seizures

2000
Stimulus-dependent modulation of [(3)H]norepinephrine release from rat neocortical slices by gabapentin and pregabalin.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:3

    Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Male; Neocortex; Norepinephrine; Potassium; Pregabalin; Rats; Rats, Sprague-Dawley

2000
Benzodiazepines and anticonvulsants for social phobia (social anxiety disorder).
    The Journal of clinical psychiatry, 2001, Volume: 62 Suppl 1

    Topics: Acetates; Alprazolam; Amines; Anticonvulsants; Benzodiazepines; Clinical Trials as Topic; Clonazepam; Cyclohexanecarboxylic Acids; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Phobic Disorders; Placebos; Pregabalin; Treatment Outcome; Valproic Acid

2001
Gabapentin inhibits the substance P-facilitated K(+)-evoked release of [(3)H]glutamate from rat caudial trigeminal nucleus slices.
    Pain, 2001, Volume: 93, Issue:2

    Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neurokinin-1 Receptor Antagonists; Organ Culture Techniques; Piperidines; Potassium; Pregabalin; Rats; Rats, Inbred Strains; Stereoisomerism; Substance P; Trigeminal Nucleus, Spinal; Tritium

2001
Mucosal uptake of gabapentin (neurontin) vs. pregabalin in the small intestine.
    Pharmaceutical research, 2001, Volume: 18, Issue:8

    Topics: Acetates; Alkaline Phosphatase; Amines; Amino Acids; Animals; Anticonvulsants; Biological Transport, Active; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Microvilli; Pregabalin; Rabbits; Rats; Sodium; Temperature

2001
Effect of gabapentin-like compounds on development and maintenance of morphine-induced conditioned place preference.
    Psychopharmacology, 2001, Volume: 157, Issue:4

    Topics: Acetates; Amines; Analgesics, Opioid; Animals; Conditioning, Operant; Cyclohexanecarboxylic Acids; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Microdialysis; Morphine; Nucleus Accumbens; Pregabalin; Rats

2001
Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex.
    Neuropharmacology, 2002, Volume: 42, Issue:2

    Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Calcium; Calcium Channel Blockers; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunoblotting; Male; Middle Aged; Neocortex; Neurons; Norepinephrine; omega-Agatoxin IVA; Potassium; Pregabalin; Quinoxalines; Receptors, AMPA; Synaptosomes

2002
Preferential action of gabapentin and pregabalin at P/Q-type voltage-sensitive calcium channels: inhibition of K+-evoked [3H]-norepinephrine release from rat neocortical slices.
    Synapse (New York, N.Y.), 2002, Sep-01, Volume: 45, Issue:3

    Topics: Acetates; Amines; Animals; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neocortex; Norepinephrine; Potassium; Pregabalin; Rats; Rats, Sprague-Dawley; Tritium

2002
Gabapentin and pregabalin suppress tactile allodynia and potentiate spinal cord stimulation in a model of neuropathy.
    European journal of pain (London, England), 2002, Volume: 6, Issue:4

    Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electric Stimulation; Electrophysiology; Gabapentin; gamma-Aminobutyric Acid; Injections; Ischemia; Male; Mononeuropathies; Pain; Pain Management; Posterior Horn Cells; Pregabalin; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Touch

2002
Gabapentin and pregabalin can interact synergistically with naproxen to produce antihyperalgesia.
    Anesthesiology, 2002, Volume: 97, Issue:5

    Topics: Acetates; Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Calcium Channels; Cyclohexanecarboxylic Acids; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Naproxen; Pregabalin; Rats; Rats, Sprague-Dawley

2002
Acute effects of gabapentin and pregabalin on rat forebrain cellular GABA, glutamate, and glutamine concentrations.
    Seizure, 2003, Volume: 12, Issue:5

    Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Injections, Intraperitoneal; Magnetic Resonance Spectroscopy; Male; Neurons; Pregabalin; Prosencephalon; Rats; Rats, Long-Evans; Vigabatrin

2003
Pregabalin and gabapentin reduce release of substance P and CGRP from rat spinal tissues only after inflammation or activation of protein kinase C.
    Pain, 2003, Volume: 105, Issue:1-2

    Topics: Acetates; Amines; Analgesics; Animals; Calcitonin Gene-Related Peptide; Cyclohexanecarboxylic Acids; Enzyme Activation; Foot; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Inflammation; Male; Phorbol 12,13-Dibutyrate; Pregabalin; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P

2003
Genotype-dependence of gabapentin and pregabalin sensitivity: the pharmacogenetic mediation of analgesia is specific to the type of pain being inhibited.
    Pain, 2003, Volume: 106, Issue:3

    Topics: Acetates; Amines; Analgesia; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Genotype; Male; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Pain; Pain Measurement; Pharmacogenetics; Pregabalin; Species Specificity

2003
Anticonvulsants as anxiolytics, part 2: Pregabalin and gabapentin as alpha(2)delta ligands at voltage-gated calcium channels.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:4

    Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Calcium Channels; Cyclohexanecarboxylic Acids; Fear; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Ligands; Pregabalin; Synaptic Transmission

2004
Anticonvulsants and the relief of chronic pain: pregabalin and gabapentin as alpha(2)delta ligands at voltage-gated calcium channels.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:5

    Topics: Acetates; Amines; Anticonvulsants; Calcium Channels; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Pain; Pain Measurement; Pregabalin; Somatoform Disorders; Synaptic Transmission

2004
Future Pain Drugs - Europe 2003. 15-16 September 2003, London, UK.
    IDrugs : the investigational drugs journal, 2003, Volume: 6, Issue:11

    Topics: Acetaminophen; Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Delivery Systems; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Levetiracetam; Nitrates; Pain; Peripheral Nervous System Diseases; Piracetam; Pregabalin; Topiramate

2003
A study comparing the actions of gabapentin and pregabalin on the electrophysiological properties of cultured DRG neurones from neonatal rats.
    BMC pharmacology, 2004, Aug-04, Volume: 4

    Topics: Amines; Animals; Animals, Newborn; Calcium; Calcium Channels; Cells, Cultured; Cyclohexanecarboxylic Acids; Electrophysiology; Fluorescent Dyes; Fura-2; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; GTP-Binding Proteins; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Pregabalin; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, GABA

2004
The biology and pharmacology of calcium channel alpha2-delta proteins Pfizer Satellite Symposium to the 2003 Society for Neuroscience Meeting. Sheraton New Orleans Hotel, New Orleans, LA November 10, 2003.
    CNS drug reviews, 2004,Summer, Volume: 10, Issue:2

    Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Binding Sites; Calcium Channels; Calcium Channels, L-Type; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Pregabalin; Rats; Societies, Scientific

2004
Mechanism of action of alpha2delta ligands: voltage sensitive calcium channel (VSCC) modulators.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:8

    Topics: Acetates; Amines; Analgesics; Anti-Anxiety Agents; Anticonvulsants; Calcium Channel Blockers; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Models, Neurological; Pregabalin; Protein Structure, Quaternary; Sodium Channels; Structure-Activity Relationship

2004
Dual effects of gabapentin and pregabalin on glutamate release at rat entorhinal synapses in vitro.
    The European journal of neuroscience, 2004, Volume: 20, Issue:6

    Topics: Amines; Analysis of Variance; Animals; Anticonvulsants; Bicuculline; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Entorhinal Cortex; Excitatory Postsynaptic Potentials; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Isoleucine; Male; Neurons; omega-Conotoxin GVIA; Patch-Clamp Techniques; Pregabalin; Rats; Rats, Wistar; Spider Venoms; Statistics, Nonparametric; Tetrodotoxin

2004
Simultaneous high-performance liquid chromatographic analysis of pregabalin, gabapentin and vigabatrin in human serum by precolumn derivatization with o-phtaldialdehyde and fluorescence detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004, Oct-25, Volume: 810, Issue:2

    Topics: Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Gabapentin; gamma-Aminobutyric Acid; Humans; Indicators and Reagents; o-Phthalaldehyde; Pregabalin; Reference Standards; Reproducibility of Results; Solutions; Specimen Handling; Spectrometry, Fluorescence; Vigabatrin

2004
Oral treatment with PD-0200347, an alpha2delta ligand, reduces the development of experimental osteoarthritis by inhibiting metalloproteinases and inducible nitric oxide synthase gene expression and synthesis in cartilage chondrocytes.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:2

    Topics: Administration, Oral; Amines; Animals; Cartilage, Articular; Chondrocytes; Cyclohexanecarboxylic Acids; Disease Models, Animal; Disease Progression; Dogs; Gabapentin; gamma-Aminobutyric Acid; Gene Expression; Immunohistochemistry; Metalloproteases; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Osteoarthritis; Pregabalin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2005
Novel cyclopropyl beta-amino acid analogues of pregabalin and gabapentin that target the alpha2-delta protein.
    Journal of medicinal chemistry, 2005, Apr-21, Volume: 48, Issue:8

    Topics: Administration, Oral; Amines; Amino Acid Transport System L; Amino Acids; Animals; Anticonvulsants; Biological Transport, Active; Blood-Brain Barrier; Calcium Channels; CHO Cells; Cricetinae; Cricetulus; Cyclization; Cyclohexanecarboxylic Acids; Cyclopropanes; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Injections, Intraventricular; Ion Channel Gating; Male; Mice; Mice, Inbred DBA; Nitriles; Pregabalin; Protein Subunits; Rats; Rats, Sprague-Dawley; Swine

2005
Design, synthesis, and preliminary evaluation of gabapentin-pregabalin mutual prodrugs in relieving neuropathic pain.
    Archiv der Pharmazie, 2005, Volume: 338, Issue:8

    Topics: Amines; Analgesics, Non-Narcotic; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Male; Molecular Structure; Pregabalin; Prodrugs; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Structure-Activity Relationship

2005
Carboxylate bioisosteres of pregabalin.
    Bioorganic & medicinal chemistry letters, 2006, Jul-01, Volume: 16, Issue:13

    Topics: Amines; Animals; Anticonvulsants; Binding Sites; Carboxylic Acids; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsy, Reflex; Gabapentin; gamma-Aminobutyric Acid; Mice; Mice, Inbred DBA; Molecular Structure; Pregabalin; Protein Subunits; Stereoisomerism; Structure-Activity Relationship

2006
The P/Q-type voltage-dependent calcium channel as pharmacological target in spinocerebellar ataxia type 6: gabapentin and pregabalin may be of therapeutic benefit.
    Medical hypotheses, 2007, Volume: 68, Issue:1

    Topics: Amines; Calcium Channel Blockers; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cyclohexanecarboxylic Acids; Drug Delivery Systems; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Spinal Cord; Spinocerebellar Ataxias

2007
Cost-effectiveness of pregabalin for the management of neuropathic pain associated with diabetic peripheral neuropathy and postherpetic neuralgia: a Canadian perspective.
    Clinical therapeutics, 2006, Volume: 28, Issue:11

    Topics: Amines; Analgesics; Canada; Clinical Trials as Topic; Costs and Cost Analysis; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Data Collection; Diabetic Neuropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Models, Theoretical; Neuralgia, Postherpetic; Predictive Value of Tests; Pregabalin; Time Factors

2006
Antihyperalgesic efficacy of lacosamide in a rat model for muscle pain induced by TNF.
    Neuropharmacology, 2007, Volume: 52, Issue:5

    Topics: Acetamides; Amines; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Hyperalgesia; Lacosamide; Male; Muscular Diseases; Pain; Pregabalin; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factors

2007
Alpha-2-delta ligands for singultus (hiccup) treatment: three case reports.
    Journal of pain and symptom management, 2007, Volume: 33, Issue:6

    Topics: Aged; Amines; Anticonvulsants; Calcium Channels; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Ligands; Male; Middle Aged; Pregabalin

2007
Postoperative pain management--is there a role for gabapentin or pregabalin?
    Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2007, Volume: 22, Issue:2

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Pregabalin

2007
Pregabalin and duloxetine for the treatment of neuropathic pain disorders.
    Journal of pain & palliative care pharmacotherapy, 2007, Volume: 21, Issue:1

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain; Pregabalin; Randomized Controlled Trials as Topic; Thiophenes

2007
Defensive-like behaviors induced by ultrasound: further pharmacological characterization in Lister-hooded rats.
    Psychopharmacology, 2007, Volume: 194, Issue:2

    Topics: Amines; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Bridged Bicyclo Compounds; Buspirone; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Diazepam; Dose-Response Relationship, Drug; Escape Reaction; Fear; Freezing Reaction, Cataleptic; Gabapentin; gamma-Aminobutyric Acid; Haloperidol; Imidazoles; Male; Morphine; Motor Activity; Nociceptin Receptor; Pregabalin; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, Opioid; Spiro Compounds; Thiazoles; Ultrasonics

2007
Career lifetime advances and key developments: diabetes.
    Clinical medicine (London, England), 2007, Volume: 7, Issue:3

    Topics: Amines; Amitriptyline; Analgesics; Antidepressive Agents; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Thiophenes

2007
[The 10-minute-consultation: chronic singultus].
    MMW Fortschritte der Medizin, 2007, Mar-22, Volume: 149, Issue:12

    Topics: Aged; Amines; Anti-Ulcer Agents; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Male; Omeprazole; Pregabalin; Recurrence

2007
A retrospective evaluation of the use of gabapentin and pregabalin in patients with postherpetic neuralgia in usual-care settings.
    Clinical therapeutics, 2007, Volume: 29, Issue:8

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Amines; Analgesics; Analgesics, Opioid; Anticonvulsants; Cyclohexanecarboxylic Acids; Databases as Topic; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Male; Middle Aged; Neuralgia, Postherpetic; Pain Measurement; Practice Patterns, Physicians'; Pregabalin; Retrospective Studies; Tramadol; Treatment Outcome; United States

2007
[Should we care about pregabalin for elderly patients with a history of cardiac dysrhythmia?].
    La Revue de medecine interne, 2008, Volume: 29, Issue:2

    Topics: Aged, 80 and over; Amines; Analgesics; Atrial Fibrillation; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Failure; Herpes Zoster; Humans; Neuritis; Pregabalin; Tachycardia, Paroxysmal

2008
Differential modulation of K(+)-evoked (3)H-neurotransmitter release from human neocortex by gabapentin and pregabalin.
    Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 376, Issue:5

    Topics: Acetylcholine; Adolescent; Adult; Aged; Amines; Analgesics; Anticonvulsants; Calcium Channels; Child; Cyclohexanecarboxylic Acids; Dopamine; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Isoleucine; Ligands; Male; Middle Aged; Neocortex; Norepinephrine; Potassium; Pregabalin; Serotonin; Stereoisomerism

2008
Fibromyalgia: understanding a mysterious ailment.
    The Johns Hopkins medical letter health after 50, 2007, Volume: 19, Issue:9

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Nociceptors; Pregabalin

2007
Defining neuralgiform headache with ipsilateral autonomic symptoms: case report in a headache center.
    Internal and emergency medicine, 2008, Volume: 3, Issue:4

    Topics: Aged; Amines; Analgesics, Opioid; Anticonvulsants; Autonomic Nervous System; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Ketorolac; Male; Pregabalin; Tramadol; Trigeminal Neuralgia

2008
Pregabalin and gabapentin inhibit substance P-induced NF-kappaB activation in neuroblastoma and glioma cells.
    Journal of cellular biochemistry, 2008, Oct-01, Volume: 105, Issue:2

    Topics: Amines; Animals; Cell Line, Tumor; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Glioma; Humans; Inflammation; Neuroblastoma; NF-kappa B; Pregabalin; Rats; Rats, Sprague-Dawley; Signal Transduction; Substance P

2008
Cost-effectiveness analysis of a lidocaine 5% medicated plaster compared with gabapentin and pregabalin for treating postherpetic neuralgia: a german perspective.
    Clinical drug investigation, 2008, Volume: 28, Issue:9

    Topics: Administration, Cutaneous; Amines; Analgesics; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Delphi Technique; Drug Costs; Endpoint Determination; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Germany; Lidocaine; Markov Chains; Models, Economic; Models, Statistical; National Health Programs; Neuralgia, Postherpetic; Pain Measurement; Pregabalin; Quality-Adjusted Life Years

2008
Is there a role for anticonvulsants in the management of rheumatic pain?
    Joint bone spine, 2008, Volume: 75, Issue:6

    Topics: Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Nervous System Diseases; Pain; Pregabalin; Rheumatic Diseases; Rheumatology

2008
Improvement in psoriasis following treatment with gabapentin and pregabalin.
    American journal of clinical dermatology, 2008, Volume: 9, Issue:6

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pregabalin; Psoriasis; Treatment Outcome

2008
Effects of gabapentin and pregabalin on K+-evoked 3H-GABA and 3H-glutamate release from human neocortical synaptosomes.
    Naunyn-Schmiedeberg's archives of pharmacology, 2009, Volume: 379, Issue:4

    Topics: Adolescent; Adult; Aged; Amines; Amino Acids, Cyclic; Anticonvulsants; Aspartic Acid; Calcium Channel Blockers; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Exocytosis; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Infant; Isoleucine; Male; Middle Aged; Neocortex; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Oximes; Potassium; Pregabalin; Synaptosomes; Tacrolimus; Young Adult

2009
A cost-utility comparison of four first-line medications in painful diabetic neuropathy.
    PharmacoEconomics, 2008, Volume: 26, Issue:12

    Topics: Amines; Analgesics; Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Desipramine; Diabetic Neuropathies; Duloxetine Hydrochloride; Economics, Pharmaceutical; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pregabalin; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Thiophenes

2008
Gabapentin and post-thoracotomy shoulder pain.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2008, Volume: 55, Issue:12

    Topics: Amines; Analgesics; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Pregabalin; Shoulder Pain; Thoracotomy

2008
Simultaneous determination of three anticonvulsants using hydrophilic interaction LC-MS.
    Journal of separation science, 2009, Volume: 32, Issue:2

    Topics: Amines; Anticonvulsants; Calibration; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Pregabalin; Solutions; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Temperature; Vigabatrin; Water

2009
[New antiepileptic drugs].
    La Revue de medecine interne, 2009, Volume: 30, Issue:4

    Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Oxcarbazepine; Piracetam; Pregabalin; Triazines; Zonisamide

2009
Gabapentin and pregabalin ameliorate mechanical hypersensitivity after spinal cord injury in mice.
    European journal of pharmacology, 2009, May-01, Volume: 609, Issue:1-3

    Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hypersensitivity; Mice; Mice, Inbred Strains; Motor Activity; Pregabalin; Recovery of Function; Spinal Cord Injuries; Time Factors

2009
Pregabalin- and gabapentin-associated myoclonus in a patient with chronic renal failure.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Oct-15, Volume: 24, Issue:13

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Male; Middle Aged; Myoclonus; Pregabalin

2009
[Treatment of neuropathies].
    Orvosi hetilap, 2010, Jan-10, Volume: 151, Issue:2

    Topics: Adjuvants, Immunologic; Adrenergic Uptake Inhibitors; Amines; Analgesics; Antioxidants; Capsaicin; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Polyneuropathies; Pregabalin; Sensory System Agents; Thiamine; Thioctic Acid; Thiophenes

2010
Substitution of gabapentin therapy with pregabalin therapy in neuropathic pain due to peripheral neuropathy.
    Pain medicine (Malden, Mass.), 2010, Volume: 11, Issue:3

    Topics: Aged; Amines; Analgesics; Cohort Studies; Cyclohexanecarboxylic Acids; Data Interpretation, Statistical; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Peripheral Nervous System Diseases; Pregabalin; Quality of Life; Treatment Outcome

2010
Cost effectiveness of pregabalin in the treatment of fibromyalgia from a UK perspective.
    Current medical research and opinion, 2010, Volume: 26, Issue:4

    Topics: Adult; Amines; Amitriptyline; Analgesics; Antidepressive Agents; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Drug Costs; Duloxetine Hydrochloride; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Markov Chains; Models, Econometric; Pregabalin; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Thiophenes; Tramadol; United Kingdom

2010
Genotoxic evaluation of antiepileptic drugs by Drosophila somatic mutation and recombination test.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:10

    Topics: Abnormalities, Drug-Induced; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drosophila melanogaster; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Mutagenicity Tests; Mutagens; Phenytoin; Pregabalin; Recombination, Genetic; Survival; Wings, Animal

2010
Pregabalin and gabapentin in matched patients with peripheral neuropathic pain in routine medical practice in a primary care setting: Findings from a cost-consequences analysis in a nested case-control study.
    Clinical therapeutics, 2010, Volume: 32, Issue:7

    Topics: Aged; Amines; Analgesics; Case-Control Studies; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Costs; Efficiency; Female; Gabapentin; gamma-Aminobutyric Acid; Health Care Costs; Humans; Male; Middle Aged; Pain Measurement; Peripheral Nervous System Diseases; Pregabalin; Primary Health Care

2010
Comparing healthcare costs of Medicaid patients with postherpetic neuralgia (PHN) treated with lidocaine patch 5% versus gabapentin or pregabalin.
    Journal of medical economics, 2010, Volume: 13, Issue:3

    Topics: Amines; Analgesics; Costs and Cost Analysis; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Health Care Costs; Health Services; Humans; Insurance Claim Review; Lidocaine; Male; Medicaid; Middle Aged; Neuralgia, Postherpetic; Pregabalin; Retrospective Studies; Transdermal Patch; United States

2010
Gabapentin and pregabalin inhibit the itch-associated response induced by the repeated application of oxazolone in mice.
    Journal of pharmacological sciences, 2011, Volume: 115, Issue:1

    Topics: Amines; Animals; Calcium Channels; Chronic Disease; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Eruptions; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Injections, Spinal; Male; Mice; Mice, Inbred BALB C; Oxazolone; Pregabalin; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Time Factors; Up-Regulation; Urticaria

2011
Is there a recreational misuse potential for pregabalin? Analysis of anecdotal online reports in comparison with related gabapentin and clonazepam data.
    Psychotherapy and psychosomatics, 2011, Volume: 80, Issue:2

    Topics: Amines; Anticonvulsants; Clonazepam; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Routes; Drug and Narcotic Control; Drug Interactions; Europe; Gabapentin; gamma-Aminobutyric Acid; Humans; Illicit Drugs; Pregabalin; Substance Withdrawal Syndrome; Substance-Related Disorders

2011
Amperometric measurement of glutamate release modulation by gabapentin and pregabalin in rat neocortical slices: role of voltage-sensitive Ca2+ α2δ-1 subunit.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 338, Issue:1

    Topics: Amines; Animals; Calcium Channels; Calcium Channels, L-Type; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Mice; Mice, Mutant Strains; Mice, Transgenic; Microelectrodes; Neocortex; Point Mutation; Pregabalin; Rats; Rats, Sprague-Dawley

2011
Effects of antiepileptic drugs on GABA release from rat and human neocortical synaptosomes.
    Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 384, Issue:1

    Topics: Adolescent; Adult; Aged; Amines; Animals; Anticonvulsants; Calcium; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Neocortex; Nipecotic Acids; Oximes; Phenytoin; Piracetam; Potassium; Pregabalin; Rats; Rats, Wistar; Synaptosomes; Tetanus Toxin; Tetrodotoxin; Triazines; Valproic Acid; Veratridine; Young Adult

2011
Possible heart failure associated with pregabalin use: case report.
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2011, Volume: 23, Issue:2

    Topics: Amines; Analgesics; Back Pain; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Edema; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Failure; Humans; Middle Aged; Neuralgia; Pregabalin; Tramadol

2011
Replacement of gabapentin with pregabalin in postherpetic neuralgia therapy.
    Pain medicine (Malden, Mass.), 2011, Volume: 12, Issue:7

    Topics: Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain Measurement; Pregabalin; Treatment Outcome

2011
An in vitro model for testing drugs to treat tinnitus.
    European journal of pharmacology, 2011, Sep-30, Volume: 667, Issue:1-3

    Topics: Amines; Animals; Antioxidants; Calcium Channel Blockers; Carnitine; Convulsants; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; Indoles; Mice; Neurons; Pentylenetetrazole; Potassium Channel Blockers; Pregabalin; Pyridines; Tinnitus

2011
Urine drug testing of chronic pain patients. IV. prevalence of gabapentin and pregabalin.
    Journal of analytical toxicology, 2011, Volume: 35, Issue:6

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Patient Compliance; Pregabalin

2011
Cost analysis of adding pregabalin or gabapentin to the management of community-treated patients with peripheral neuropathic pain.
    Journal of evaluation in clinical practice, 2012, Volume: 18, Issue:6

    Topics: Aged; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Comorbidity; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Health Services; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Pregabalin; Retrospective Studies; Socioeconomic Factors

2012
Interactions of pregabalin with gabapentin, levetiracetam, tiagabine and vigabatrin in the mouse maximal electroshock-induced seizure model: a type II isobolographic analysis.
    Epilepsy research, 2012, Volume: 98, Issue:2-3

    Topics: Amines; Animals; Anticonvulsants; Avoidance Learning; Confidence Intervals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Levetiracetam; Male; Mice; Motor Activity; Piracetam; Pregabalin; Seizures; Vigabatrin

2012
Economic evaluation of duloxetine as a first-line treatment for painful diabetic peripheral neuropathy in Mexico.
    Journal of medical economics, 2012, Volume: 15, Issue:2

    Topics: Amines; Analgesics; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Dopamine Uptake Inhibitors; Drug Costs; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Mexico; Pregabalin; Thiophenes

2012
Costs of pregabalin or gabapentin for painful diabetic peripheral neuropathy.
    Journal of medical economics, 2012, Volume: 15, Issue:2

    Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Databases, Factual; Diabetic Nephropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Health Resources; Humans; Male; Middle Aged; Pain; Pregabalin; Prescription Fees; Retrospective Studies; United States

2012
Pharmacological characterization of lysophosphatidic acid-induced pain with clinically relevant neuropathic pain drugs.
    European journal of pain (London, England), 2012, Volume: 16, Issue:7

    Topics: Amines; Analgesics; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Indomethacin; Lysophospholipids; Male; Mice; Morphine; Motor Activity; Neuralgia; Neurons; Pregabalin; Spinal Cord

2012
The efficacy of morphine, pregabalin, gabapentin, and duloxetine on mechanical allodynia is different from that on neuroma pain in the rat neuropathic pain model.
    Anesthesia and analgesia, 2012, Volume: 115, Issue:1

    Topics: Administration, Oral; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Morphine; Neuralgia; Neuroma; Pain Measurement; Pain Threshold; Pregabalin; Rats; Rats, Sprague-Dawley; Thiophenes; Time Factors

2012
Statement of the AGNP in the Context of the Planned Formation of a Fixed Reference Price Group "GABA-Analogues", November 21, 2011.
    Pharmacopsychiatry, 2012, Volume: 45, Issue:2

    Topics: Amines; Anti-Anxiety Agents; Anxiety Disorders; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Germany; Humans; Insurance Coverage; Insurance, Health, Reimbursement; Pregabalin; Societies, Scientific

2012
Pain alleviation and patient-reported health outcomes following switching to pregabalin in individuals with gabapentin-refractory neuropathic pain in routine medical practice.
    Clinical drug investigation, 2012, Jun-01, Volume: 32, Issue:6

    Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pregabalin; Quality of Life; Surveys and Questionnaires; Treatment Outcome

2012
Does Pregabalin (Lyrica(®) ) help patients reduce their use of benzodiazepines? A comparison with gabapentin using the Norwegian Prescription Database.
    Basic & clinical pharmacology & toxicology, 2010, Volume: 107, Issue:5

    Topics: Adolescent; Adult; Amines; Anti-Anxiety Agents; Benzodiazepines; Cyclohexanecarboxylic Acids; Databases, Factual; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization Review; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Norway; Pregabalin; Young Adult

2010
α2δ ligands act as positive modulators of adult hippocampal neurogenesis and prevent depression-like behavior induced by chronic restraint stress.
    Molecular pharmacology, 2012, Volume: 82, Issue:2

    Topics: Amines; Animals; Calcium Channels; Cell Differentiation; Cyclohexanecarboxylic Acids; Depression; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Ligands; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Pregabalin; Random Allocation; Restraint, Physical; Stress, Psychological

2012
Costs, work absence, and adherence in patients with partial onset seizures prescribed gabapentin or pregabalin.
    Epilepsy research, 2012, Volume: 102, Issue:1-2

    Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Cohort Studies; Cyclohexanecarboxylic Acids; Databases, Factual; Drug Costs; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Health Expenditures; Humans; Male; Middle Aged; Patient Compliance; Pregabalin; Sick Leave; Workers' Compensation; Young Adult

2012
Gabapentin and pregabalin: abuse and addiction.
    Prescrire international, 2012, Volume: 21, Issue:128

    Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Substance Withdrawal Syndrome; Substance-Related Disorders

2012
Chronic postsurgical pain: are we closer to understanding the puzzle?
    Anesthesia and analgesia, 2012, Volume: 115, Issue:2

    Topics: Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain, Postoperative; Pregabalin

2012
Gabapentin to pregabalin therapy transition: a pharmacokinetic simulation.
    American journal of therapeutics, 2013, Volume: 20, Issue:1

    Topics: Amines; Anticonvulsants; Computer Simulation; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Substitution; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Biological; Pregabalin

2013
Long-term outcome of Cavalier King Charles spaniel dogs with clinical signs associated with Chiari-like malformation and syringomyelia.
    The Veterinary record, 2012, Nov-17, Volume: 171, Issue:20

    Topics: Amines; Analgesics; Animals; Arnold-Chiari Malformation; Breeding; Carbazoles; Cohort Studies; Cyclohexanecarboxylic Acids; Dog Diseases; Dogs; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Neuralgia; Pregabalin; Prospective Studies; Quality of Life; Severity of Illness Index; Syringomyelia

2012
Relative potency of pregabalin, gabapentin, and morphine in a mouse model of visceral pain.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2013, Volume: 60, Issue:1

    Topics: Acetic Acid; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Morphine; Pain Measurement; Pregabalin; Visceral Pain

2013
Real-world treatment of post-herpetic neuralgia with gabapentin or pregabalin.
    Clinical drug investigation, 2013, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Delivery of Health Care; Drug Costs; Drug Substitution; Drug Therapy, Combination; Drug Utilization; Drug Utilization Review; Female; Gabapentin; gamma-Aminobutyric Acid; Guideline Adherence; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Practice Guidelines as Topic; Practice Patterns, Physicians'; Pregabalin; Retrospective Studies; Time Factors; Treatment Outcome; United States; Young Adult

2013
Rapid quantification of gabapentin, pregabalin, and vigabatrin in human serum by ultraperformance liquid chromatography with mass-spectrometric detection.
    Therapeutic drug monitoring, 2013, Volume: 35, Issue:1

    Topics: Amines; Anticonvulsants; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Tandem Mass Spectrometry; Vigabatrin

2013
Optimised protocol design for the screening of analgesic compounds in neuropathic pain.
    Journal of pharmacokinetics and pharmacodynamics, 2012, Volume: 39, Issue:6

    Topics: Amines; Analgesics; Animals; Cohort Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; Logistic Models; Models, Biological; Neuralgia; Pregabalin; Random Allocation; Rats; Rats, Sprague-Dawley

2012
Gabapentin and (S)-pregabalin decrease intracellular D-serine concentrations in PC-12 cells.
    Neuroscience letters, 2013, Feb-22, Volume: 535

    Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Intracellular Space; PC12 Cells; Pregabalin; Racemases and Epimerases; Rats; Serine; Stereoisomerism

2013
Adverse drug reactions to gabapentin and pregabalin: a review of the French pharmacovigilance database.
    Drug safety, 2013, Volume: 36, Issue:1

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Databases, Factual; France; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pregabalin

2013
Development and validation of sensitive spectrophotometric method for determination of two antiepileptics in pharmaceutical formulations.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Mar-15, Volume: 105

    Topics: Amines; Anthraquinones; Anticonvulsants; Coloring Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Limit of Detection; Pharmaceutical Preparations; Pregabalin; Spectrophotometry

2013
Pregabalin versus gabapentin in the management of peripheral neuropathic pain associated with post-herpetic neuralgia and diabetic neuropathy: a cost effectiveness analysis for the Greek healthcare setting.
    BMC neurology, 2013, Jun-04, Volume: 13

    Topics: Amines; Analgesics; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Greece; Health Care Costs; Humans; Male; Middle Aged; Neuralgia; Neuralgia, Postherpetic; Pain Measurement; Pregabalin

2013
A simple high-throughput method for determination of antiepileptic analogues of γ-aminobutyric acid in pharmaceutical dosage forms using microplate fluorescence reader.
    Chemical & pharmaceutical bulletin, 2013, Volume: 61, Issue:10

    Topics: Amines; Anticonvulsants; Capsules; Cyclohexanecarboxylic Acids; Fluorescamine; Gabapentin; gamma-Aminobutyric Acid; High-Throughput Screening Assays; Pharmaceutical Preparations; Pregabalin; Spectrometry, Fluorescence; Tablets; Temperature; Vigabatrin

2013
Clinical characteristics and medication uses among fibromyalgia patients newly prescribed amitriptyline, duloxetine, gabapentin, or pregabalin.
    Arthritis care & research, 2013, Volume: 65, Issue:11

    Topics: Amines; Amitriptyline; Analgesics; Anti-Anxiety Agents; Antidepressive Agents; Cyclohexanecarboxylic Acids; Disease Progression; Duloxetine Hydrochloride; Female; Fibromyalgia; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Pregabalin; Prescription Drugs; Retrospective Studies; Thiophenes; Treatment Outcome

2013
[Lacosamide as an alternative in the treatment of post-surgery neuropathic pain in an allergic patient].
    Revista de neurologia, 2013, Oct-01, Volume: 57, Issue:7

    Topics: Acetamides; Adult; Amines; Analgesics; Anticonvulsants; Brachial Plexus Neuropathies; Contraindications; Cyclohexanecarboxylic Acids; Drug Hypersensitivity; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lacosamide; Magnetic Resonance Imaging; Neuralgia; Neurofibroma; Pain, Postoperative; Peripheral Nervous System Neoplasms; Pregabalin

2013
Adding pregabalin or gabapentin for the management of community-treated patients with painful diabetic peripheral neuropathy: a comparative cost analysis.
    Clinical drug investigation, 2013, Volume: 33, Issue:11

    Topics: Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Diabetic Nephropathies; Drug Costs; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Longitudinal Studies; Male; Medical Audit; Middle Aged; Pregabalin; Retrospective Studies

2013
Effects of derivatization reagents consisting of n-alkyl chloroformate/n-alcohol combinations in LC-ESI-MS/MS analysis of zwitterionic antiepileptic drugs.
    Talanta, 2013, Nov-15, Volume: 116

    Topics: 1-Propanol; Amines; Anticonvulsants; Butanols; Cyclohexanecarboxylic Acids; Esters; Ethanol; Formates; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Methanol; Pregabalin; Solutions; Spectrometry, Mass, Electrospray Ionization; Vigabatrin

2013
Gabapentinoid abuse in order to potentiate the effect of methadone: a survey among substance misusers.
    European addiction research, 2014, Volume: 20, Issue:3

    Topics: Amines; Behavior, Addictive; Cyclohexanecarboxylic Acids; Data Collection; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Humans; Methadone; Opioid-Related Disorders; Pregabalin; Scotland; Substance-Related Disorders

2014
Bad medicine: gabapentin and pregabalin.
    BMJ (Clinical research ed.), 2013, Nov-08, Volume: 347

    Topics: Amines; Analgesics; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Drug Overdose; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Iatrogenic Disease; Male; Practice Patterns, Physicians'; Pregabalin; Prescription Drug Misuse; Prescription Drugs; United States

2013
Effectiveness of duloxetine compared with pregabalin and gabapentin in diabetic peripheral neuropathic pain: results from a German observational study.
    The Clinical journal of pain, 2014, Volume: 30, Issue:10

    Topics: Aged; Amines; Analgesics; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Health Surveys; Humans; Male; Middle Aged; Pain Measurement; Pregabalin; Prospective Studies; Thiophenes; Treatment Outcome

2014
Drugs for neuropathic pain.
    BMJ (Clinical research ed.), 2013, Dec-19, Volume: 347

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pregabalin; Thiophenes; Treatment Outcome

2013
Should anaesthetists routinely use a gabapentinoid perioperatively?
    British journal of hospital medicine (London, England : 2005), 2014, Volume: 75, Issue:1

    Topics: Amines; Analgesics; Anesthesiology; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Perioperative Care; Pregabalin

2014
Painful traumatic trigeminal neuropathy: an open study on the pharmacotherapeutic response to stepped treatment.
    Journal of oral & facial pain and headache, 2014,Winter, Volume: 28, Issue:1

    Topics: Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Baclofen; Carbamazepine; Clinical Protocols; Cohort Studies; Cyclohexanecarboxylic Acids; Drug Combinations; Duloxetine Hydrochloride; Female; Follow-Up Studies; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medical Records; Middle Aged; Nortriptyline; Pain; Pain Measurement; Pregabalin; Prognosis; Prospective Studies; Thiophenes; Treatment Outcome; Trigeminal Nerve Injuries; Trigeminal Neuralgia

2014
Antinociceptive effects of mirtazapine, pregabalin, and gabapentin after chronic constriction injury of the infraorbital nerve in rats.
    Journal of oral & facial pain and headache, 2014,Winter, Volume: 28, Issue:1

    Topics: Adrenergic alpha-Antagonists; Amines; Analgesics; Animals; Cranial Nerve Injuries; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Mianserin; Mirtazapine; Neuralgia; Nociceptive Pain; Orbit; Pain Threshold; Pregabalin; Rats; Rats, Sprague-Dawley; Time Factors; Touch

2014
Chronic postsurgical pain: prevention and management.
    Journal of pain & palliative care pharmacotherapy, 2014, Volume: 28, Issue:1

    Topics: Amines; Chronic Pain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Management; Pain, Postoperative; Pregabalin; Risk Factors

2014
Effect of variability in the 7-day baseline pain diary on the assay sensitivity of neuropathic pain randomized clinical trials: an ACTTION study.
    Pain, 2014, Volume: 155, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Neuralgia, Postherpetic; Pain Measurement; Pregabalin; Randomized Controlled Trials as Topic; Self Report; Treatment Outcome; United States

2014
Profiles of pregabalin and gabapentin abuse by postmortem toxicology.
    Forensic science international, 2014, Volume: 241

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Female; Finland; Forensic Toxicology; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Male; Mass Spectrometry; Middle Aged; Narcotics; Postmortem Changes; Pregabalin; Substance-Related Disorders; Young Adult

2014
Simultaneous determination of gabapentin, pregabalin, vigabatrin, and topiramate in plasma by HPLC with fluorescence detection.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, Jul-01, Volume: 962

    Topics: Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Fluorescence; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Pregabalin; Solid Phase Extraction; Topiramate; Vigabatrin

2014
Augmentation in restless legs syndrome patients in Korea.
    Sleep & breathing = Schlaf & Atmung, 2015, Volume: 19, Issue:2

    Topics: Aged; Aged, 80 and over; Amines; Benzothiazoles; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Disease Progression; Dopamine Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Korea; Long-Term Care; Male; Middle Aged; Pramipexole; Pregabalin; Restless Legs Syndrome; Risk Factors

2015
Misuse of the γ-aminobutyric acid analogues baclofen, gabapentin and pregabalin in the UK.
    British journal of clinical pharmacology, 2014, Volume: 78, Issue:1

    Topics: Adolescent; Adult; Amines; Baclofen; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Humans; Illicit Drugs; Male; Middle Aged; Pregabalin; Prescription Drug Misuse; United Kingdom; Young Adult

2014
Analysis of the long-term actions of gabapentin and pregabalin in dorsal root ganglia and substantia gelatinosa.
    Journal of neurophysiology, 2014, Nov-15, Volume: 112, Issue:10

    Topics: Amines; Analgesics; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cyclohexanecarboxylic Acids; Excitatory Postsynaptic Potentials; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Immunohistochemistry; Inhibitory Postsynaptic Potentials; Male; Microscopy, Confocal; Neurons; Patch-Clamp Techniques; Pregabalin; Rats, Sprague-Dawley; Substantia Gelatinosa; Tissue Culture Techniques

2014
Simultaneous analysis of 22 antiepileptic drugs in postmortem blood, serum and plasma using LC-MS-MS with a focus on their role in forensic cases.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:8

    Topics: Amines; Anticonvulsants; Carbamazepine; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Limit of Detection; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tiagabine; Topiramate; Triazines; Valproic Acid

2014
Comparison of the effects of gabapentin and pregabalin on wound healing in rats.
    International wound journal, 2016, Volume: 13, Issue:5

    Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain; Pregabalin; Rats; Rats, Wistar; Treatment Outcome; Wound Healing

2016
Patterns of health care utilization related to initiation of amitriptyline, duloxetine, gabapentin, or pregabalin in fibromyalgia.
    Arthritis research & therapy, 2015, Jan-28, Volume: 17

    Topics: Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Cohort Studies; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Health Services; Humans; Male; Medication Adherence; Middle Aged; Patient Acceptance of Health Care; Pregabalin

2015
A comparison of pregabalin and gabapentin in palliative care #289.
    Journal of palliative medicine, 2015, Volume: 18, Issue:4

    Topics: Amines; Analgesics; Biological Availability; Costs and Cost Analysis; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Palliative Care; Pregabalin

2015
Experience from therapeutic drug monitoring and gender aspects of gabapentin and pregabalin in clinical practice.
    Seizure, 2015, Volume: 28

    Topics: Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Monitoring; Drug Prescriptions; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Longitudinal Studies; Male; Middle Aged; Neuralgia; Norway; Pregabalin; Retrospective Studies; Sex Characteristics

2015
Gabapentin and pregabalin: hepatic and haematological toxicity.
    Prescrire international, 2014, Volume: 23, Issue:154

    Topics: Amines; Analgesics; Chemical and Drug Induced Liver Injury; Cyclohexanecarboxylic Acids; France; Gabapentin; gamma-Aminobutyric Acid; Hematologic Diseases; Humans; Pharmacovigilance; Pregabalin; Severity of Illness Index

2014
Antinociceptive and hypnotic activities of pregabalin in a neuropathic pain-like model in mice.
    Pharmacology, biochemistry, and behavior, 2015, Volume: 135

    Topics: Amines; Analgesics; Animals; Cerebral Cortex; Cyclohexanecarboxylic Acids; Electroencephalography; Gabapentin; gamma-Aminobutyric Acid; Genes, fos; Hot Temperature; Hyperalgesia; Hypnotics and Sedatives; Male; Mice; Mice, Inbred C57BL; Neuralgia; Pain Measurement; Physical Stimulation; Postural Balance; Pregabalin; Sciatic Neuropathy; Sleep Wake Disorders; Sleep, REM

2015
Suboptimal Treatment of Diabetic Peripheral Neuropathic Pain in the United States.
    Pain medicine (Malden, Mass.), 2015, Volume: 16, Issue:11

    Topics: Adult; Aged; Amines; Antidepressive Agents; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pregabalin; Quality of Life; Retrospective Studies; Treatment Outcome; United States

2015
Routine prescribing of gabapentin or pregabalin in supportive and palliative care: what are the comparative performances of the medications in a palliative care population?
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015, Volume: 23, Issue:9

    Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Prescriptions; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Pain Measurement; Palliative Care; Pregabalin

2015
[Shingles symptoms are gone but not the pain].
    MMW Fortschritte der Medizin, 2015, Jul-23, Volume: 157, Issue:13

    Topics: Administration, Cutaneous; Administration, Oral; Aged; Amines; Amitriptyline; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cyclohexanecarboxylic Acids; Dipyrone; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Guideline Adherence; Humans; Ibuprofen; Lidocaine; Neuralgia, Postherpetic; Phenols; Pregabalin; Tapentadol; Treatment Failure

2015
[The principles of pharmacotherapy of poststroke shoulder pain].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:5

    Topics: Amines; Amitriptyline; Anti-Inflammatory Agents; Clonidine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Male; Pregabalin; Shoulder Pain; Stroke

2015
Long-term cost-effectiveness of initiating treatment for painful diabetic neuropathy with pregabalin, duloxetine, gabapentin, or desipramine.
    Pain, 2016, Volume: 157, Issue:1

    Topics: Amines; Analgesics; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Desipramine; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Health Care Costs; Humans; Models, Economic; Pregabalin; Quality-Adjusted Life Years

2016
5-HT6 receptor antagonist attenuates the memory deficits associated with neuropathic pain and improves the efficacy of gabapentinoids.
    Pharmacological reports : PR, 2015, Volume: 67, Issue:5

    Topics: Amines; Animals; Cognition; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Memory Disorders; Neuralgia; Pregabalin; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists

2015
Prediction of quality of life improvements in patients with lumbar stenosis following use of membrane stabilizing agents.
    Clinical neurology and neurosurgery, 2015, Volume: 139

    Topics: Aged; Aged, 80 and over; Amines; Calcium Channel Blockers; Comorbidity; Cyclohexanecarboxylic Acids; Decision Support Techniques; Decompression, Surgical; Depression; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Income; Lumbar Vertebrae; Male; Marital Status; Middle Aged; Nomograms; Pregabalin; Proportional Hazards Models; Quality of Life; Retrospective Studies; Risk Factors; Spinal Stenosis

2015
Homology modelling and molecular docking studies of human placental cadherin protein for its role in teratogenic effects of anti-epileptic drugs.
    Computational biology and chemistry, 2016, Volume: 60

    Topics: Acetamides; Amines; Animals; Anticonvulsants; Binding Sites; Cadherins; Calcium; Cations, Divalent; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Pregabalin; Pregnancy; Sequence Homology; Teratogens; Vigabatrin

2016
THC:CBD Observational Study Data: Evolution of Resistant MS Spasticity and Associated Symptoms.
    European neurology, 2016, Volume: 75 Suppl 1

    Topics: Adult; Amines; Baclofen; Calcium Channel Blockers; Cannabidiol; Cohort Studies; Cyclohexanecarboxylic Acids; Dronabinol; Drug Combinations; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Humans; Italy; Male; Medical Marijuana; Middle Aged; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Observational Studies as Topic; Oral Sprays; Plant Extracts; Pregabalin; Prospective Studies; Treatment Outcome

2016
Analgesic drugs and the gut - a reciprocal relationship.
    The journal of the Royal College of Physicians of Edinburgh, 2015, Volume: 45, Issue:4

    Topics: Acetaminophen; Administration, Oral; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Cyclohexanecarboxylic Acids; Digestive System Diseases; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Selective Serotonin Reuptake Inhibitors

2015
A Decade of Gabapentinoid Misuse: An Analysis of the European Medicines Agency's 'Suspected Adverse Drug Reactions' Database.
    CNS drugs, 2016, Volume: 30, Issue:7

    Topics: Adult; Amines; Analgesics, Opioid; Behavior, Addictive; Cyclohexanecarboxylic Acids; Databases, Factual; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pregabalin; Prescription Drug Misuse; Substance-Related Disorders

2016
Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain.
    The Journal of pharmacology and experimental therapeutics, 2016, Volume: 358, Issue:3

    Topics: Amines; Animals; Behavior, Animal; Cathepsins; Cyclohexanecarboxylic Acids; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Male; Mice; Neuralgia; Pregabalin; Protease Inhibitors

2016
Misuse of gabapentin and pregabalin: a marker for a more serious malaise?
    Addiction (Abingdon, England), 2016, Volume: 111, Issue:10

    Topics: Biomarkers; Gabapentin; Pregabalin; Substance-Related Disorders

2016
Gabapentin, Pregabalin and Vigabatrin Quantification in Human Serum by GC-MS After Hexyl Chloroformate Derivatization.
    Journal of analytical toxicology, 2016, Volume: 40, Issue:9

    Topics: Amines; Anticonvulsants; Calibration; Computer-Aided Design; Cyclohexanecarboxylic Acids; Formates; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Pregabalin; Vigabatrin

2016
Comparative effects of α2δ-1 ligands in mouse models of colonic hypersensitivity.
    World journal of gastroenterology, 2016, Aug-21, Volume: 22, Issue:31

    Topics: Amines; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Dextran Sulfate; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Inflammatory Bowel Diseases; Ligands; Male; Mice; Mice, Inbred C57BL; Pregabalin

2016
Cost of treatment of peripheral neuropathic pain with pregabalin or gabapentin in routine clinical practice: impact of their loss of exclusivity.
    Journal of evaluation in clinical practice, 2017, Volume: 23, Issue:2

    Topics: Adult; Aged; Amines; Analgesics; Comoros; Cyclohexanecarboxylic Acids; Electronic Health Records; Female; Gabapentin; gamma-Aminobutyric Acid; Health Expenditures; Health Services; Humans; Male; Middle Aged; Neuralgia; Pregabalin; Primary Health Care; Retrospective Studies; Severity of Illness Index; Socioeconomic Factors; Spain

2017
[Mirogabalin: The next pregabalin?]
    Semergen, 2017, Volume: 43, Issue:7

    Topics: Amines; Analgesics; Bridged Bicyclo Compounds; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin

2017
Changing general medical practices in the management of neuropathic pain
    Sante publique (Vandoeuvre-les-Nancy, France), 2016, Oct-19, Volume: 28, Issue:4

    Topics: Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; General Practitioners; Humans; Male; Middle Aged; Neuralgia; Pain Management; Practice Patterns, Physicians'; Pregabalin; Surveys and Questionnaires

2016
Donepezil, an Acetylcholinesterase Inhibitor, Can Attenuate Gabapentinoid-Induced Somnolence in Patients with Neuropathic Pain: A Retrospective Chart Review.
    Journal of pain & palliative care pharmacotherapy, 2017, Volume: 31, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amines; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Disorders of Excessive Somnolence; Donepezil; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Male; Middle Aged; Neuralgia; Pain Measurement; Piperidines; Pregabalin; Retrospective Studies

2017
Levetiracetam synergizes with gabapentin, pregabalin, duloxetine and selected antioxidants in a mouse diabetic painful neuropathy model.
    Psychopharmacology, 2017, Volume: 234, Issue:11

    Topics: Amines; Analgesics; Animals; Anticonvulsants; Antioxidants; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Levetiracetam; Male; Mice; Mice, Inbred C57BL; Piracetam; Pregabalin

2017
Validated Method for the Screening and Quantification of Baclofen, Gabapentin and Pregabalin in Human Post-Mortem Whole Blood Using Protein Precipitation and Liquid Chromatography-Tandem Mass Spectrometry.
    Journal of analytical toxicology, 2017, Jun-01, Volume: 41, Issue:5

    Topics: Amines; Autopsy; Baclofen; Chemical Precipitation; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Reproducibility of Results; Tandem Mass Spectrometry

2017
The Potential for Gabapentinoid Abuse in Pain Management.
    American journal of physical medicine & rehabilitation, 2017, Volume: 96, Issue:10

    Topics: Analgesics; Gabapentin; Humans; Neuralgia; Pain Management; Pregabalin; Substance-Related Disorders

2017
Perioperative use of gabapentinoids in France. Mismatch between clinical practice and scientific evidence.
    Anaesthesia, critical care & pain medicine, 2018, Volume: 37, Issue:1

    Topics: Anesthesia; Drug Prescriptions; Drug Utilization; Evidence-Based Medicine; Excitatory Amino Acid Antagonists; France; Gabapentin; Health Care Surveys; Humans; Pain Management; Pain Measurement; Pain, Postoperative; Perioperative Care; Pregabalin; Surveys and Questionnaires

2018
Risk to heroin users of polydrug use of pregabalin or gabapentin.
    Addiction (Abingdon, England), 2017, Volume: 112, Issue:9

    Topics: Adult; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Interactions; Drug Overdose; Drug Users; England; Female; Gabapentin; gamma-Aminobutyric Acid; Heroin Dependence; Humans; Male; Mice; Middle Aged; Pregabalin; Risk; Wales; Young Adult

2017
Characteristics, resource utilization and safety profile of patients prescribed with neuropathic pain treatments: a real-world evidence study on general practices in Europe - the role of the lidocaine 5% medicated plaster.
    Current medical research and opinion, 2017, Volume: 33, Issue:8

    Topics: Aged; Aged, 80 and over; Amines; Anesthetics, Local; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Europe; Female; Gabapentin; gamma-Aminobutyric Acid; General Practice; Humans; Lidocaine; Male; Middle Aged; Neuralgia; Pregabalin; Retrospective Studies; Treatment Outcome

2017
Pregabalin and heart failure: A population-based study.
    Pharmacoepidemiology and drug safety, 2017, Volume: 26, Issue:9

    Topics: Aged; Aged, 80 and over; Amines; Anticonvulsants; Calcium Channel Blockers; Cohort Studies; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Failure; Humans; Male; Ontario; Population Surveillance; Pregabalin; Retrospective Studies; Seizures

2017
Adverse pregnancy outcomes in women exposed to gabapentin and pregabalin: data from a population-based study.
    Journal of neurology, neurosurgery, and psychiatry, 2018, Volume: 89, Issue:2

    Topics: Abortion, Induced; Abortion, Spontaneous; Adult; Anticonvulsants; Congenital Abnormalities; Female; Gabapentin; Heart Septal Defects, Ventricular; Humans; Infant, Newborn; Infant, Small for Gestational Age; Italy; Pregabalin; Pregnancy; Premature Birth; Risk Factors

2018
Gabapentin and Pregabalin for Pain - Is Increased Prescribing a Cause for Concern?
    The New England journal of medicine, 2017, Aug-03, Volume: 377, Issue:5

    Topics: Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Drug Approval; Drug Utilization; Gabapentin; gamma-Aminobutyric Acid; Humans; Inappropriate Prescribing; Neuralgia; Off-Label Use; Pregabalin; United States; United States Food and Drug Administration

2017
You Abused What? Getting High with Unique Medications.
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2017, Volume: 70, Issue:1

    Topics: Amines; Anticonvulsants; Antidiarrheals; Antipsychotic Agents; Antitussive Agents; Cyclohexanecarboxylic Acids; Dextromethorphan; Drug Misuse; Gabapentin; gamma-Aminobutyric Acid; Humans; Loperamide; Pregabalin; Quetiapine Fumarate; Substance Withdrawal Syndrome; Substance-Related Disorders

2017
Use of gabapentin and pregabalin for pruritus and neuropathic pain associated with major burn injury: A retrospective chart review.
    Burns : journal of the International Society for Burn Injuries, 2018, Volume: 44, Issue:2

    Topics: Adolescent; Analgesics; Burns; Child; Child, Preschool; Female; Gabapentin; Humans; Infant; Male; Neuralgia; Pain Measurement; Pregabalin; Pruritus; Retrospective Studies; Young Adult

2018
Anti‑inflammatory actions of gabapentin and pregabalin on the substance P‑induced mitogen‑activated protein kinase activation in U373 MG human glioblastoma astrocytoma cells.
    Molecular medicine reports, 2017, Volume: 16, Issue:5

    Topics: Amines; Anti-Inflammatory Agents; Astrocytoma; Cell Line, Tumor; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glioblastoma; Humans; Interleukin-6; Interleukin-8; MAP Kinase Signaling System; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pregabalin; Receptors, Neurokinin-1; Substance P

2017
Comparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis.
    Epilepsia, 2017, Volume: 58, Issue:10

    Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Ataxia; Benzodiazepines; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Databases, Factual; Diplopia; Dizziness; Epilepsy, Temporal Lobe; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Humans; Lamotrigine; Lethargy; Male; Middle Aged; Oxcarbazepine; Pregabalin; Retrospective Studies; Sclerosis; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Vertigo; Vigabatrin; Vision Disorders; Young Adult

2017
Effects of S 38093, an antagonist/inverse agonist of histamine H3 receptors, in models of neuropathic pain in rats.
    European journal of pain (London, England), 2018, Volume: 22, Issue:1

    Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Histamine Antagonists; Hyperalgesia; Male; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Pain Threshold; Pregabalin; Rats; Rats, Sprague-Dawley

2018
UK government to reclassify pregabalin and gabapentin after rise in deaths.
    BMJ (Clinical research ed.), 2017, 09-25, Volume: 358

    Topics: Adverse Drug Reaction Reporting Systems; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Databases, Factual; Gabapentin; gamma-Aminobutyric Acid; Humans; Practice Patterns, Physicians'; Pregabalin; State Medicine; United Kingdom

2017
Misuse of gabapentin and pregabalin may be underestimated.
    BMJ (Clinical research ed.), 2017, 11-21, Volume: 359

    Topics: Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Government; Pregabalin; United Kingdom

2017
Generalized unprovoked vulvodynia; A retrospective study on the efficacy of treatment with amitriptyline, gabapentin or pregabalin.
    European journal of obstetrics, gynecology, and reproductive biology, 2018, Volume: 220

    Topics: Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain Measurement; Pregabalin; Retrospective Studies; Treatment Outcome; Vulvodynia

2018
Intentional Drug Overdose Involving Pregabalin and Gabapentin: Findings from the National Self-Harm Registry Ireland, 2007-2015.
    Clinical drug investigation, 2018, Volume: 38, Issue:4

    Topics: Adult; Alcohol Drinking; Amines; Cyclohexanecarboxylic Acids; Drug Overdose; Emergency Service, Hospital; Female; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Ireland; Male; Middle Aged; Pregabalin; Registries; Young Adult

2018
Evaluating the effectiveness of antidepressant therapy adjuvant to gabapentin and pregabalin for treatment of SCI-related neuropathic pain.
    The journal of spinal cord medicine, 2018, Volume: 41, Issue:6

    Topics: Adult; Analgesics; Antidepressive Agents; Chemotherapy, Adjuvant; Cohort Studies; Drug Therapy, Combination; Female; Gabapentin; Humans; Male; Middle Aged; Neuralgia; Pregabalin; Spinal Cord Injuries

2018
Patterns of pain medication use in older individuals with cardiovascular disease.
    Current medical research and opinion, 2018, Volume: 34, Issue:5

    Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Female; Gabapentin; Humans; Inappropriate Prescribing; Male; Neuralgia; Polypharmacy; Pregabalin; Retrospective Studies; Tramadol

2018
Pattern of perioperative gabapentinoid use and risk for postoperative naloxone administration.
    British journal of anaesthesia, 2018, Volume: 120, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Anesthesia Recovery Period; Case-Control Studies; Female; Gabapentin; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Perioperative Period; Postoperative Care; Postoperative Complications; Pregabalin; Respiratory Insufficiency; Retrospective Studies; Risk; Young Adult

2018
Gabapentin and Pregabalin for the Treatment of Anxiety Disorders.
    Clinical pharmacology in drug development, 2018, Volume: 7, Issue:3

    Topics: Anti-Anxiety Agents; Anxiety Disorders; GABA Agents; Gabapentin; Humans; Pregabalin; Treatment Outcome

2018
Cost of treating peripheral neuropathic pain with pregabalin or gabapentin at therapeutic doses in routine practice.
    Journal of comparative effectiveness research, 2018, Volume: 7, Issue:7

    Topics: Adult; Amines; Analgesics; Electronic Health Records; Female; Gabapentin; Health Resources; Humans; Male; Middle Aged; Neuralgia; Pain Management; Pregabalin; Primary Health Care; Retrospective Studies; Sick Leave; Young Adult

2018
Gabapentin and Pregabalin Use and Association with Adverse Outcomes among Hemodialysis Patients.
    Journal of the American Society of Nephrology : JASN, 2018, Volume: 29, Issue:7

    Topics: Accidental Falls; Aged; Analgesics; Emergency Service, Hospital; Female; Fractures, Bone; Gabapentin; Hospitalization; Humans; Male; Medicare; Mental Disorders; Middle Aged; Pregabalin; Proportional Hazards Models; Renal Dialysis; Renal Insufficiency, Chronic; Risk Factors; United States

2018
Severe eosinophilic colitis caused by neuropathic agents in a patient with chronic fatigue syndrome and functional abdominal pain: case report and review of the literature.
    Zeitschrift fur Gastroenterologie, 2018, Volume: 56, Issue:6

    Topics: Abdominal Pain; Adolescent; Colitis; Colitis, Microscopic; Eosinophilia; Fatigue Syndrome, Chronic; Female; Gabapentin; Humans; Pregabalin

2018
Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database.
    Drug safety, 2018, Volume: 41, Issue:12

    Topics: Age Factors; Aged; Analgesics; Atrial Fibrillation; Cohort Studies; Databases, Factual; Electronic Prescribing; Female; Gabapentin; Humans; Male; Population Surveillance; Pregabalin; Retrospective Studies; Risk Factors

2018
Evaluation of composite responder outcomes of pain intensity and physical function in neuropathic pain clinical trials: an ACTTION individual patient data analysis.
    Pain, 2018, Volume: 159, Issue:11

    Topics: Aged; Aged, 80 and over; Analgesics; Clinical Trials as Topic; Double-Blind Method; Duloxetine Hydrochloride; Exercise; Female; Gabapentin; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Pregabalin; Treatment Outcome

2018
Pushing the Limits of Computational Structure-Based Drug Design with a Cryo-EM Structure: The Ca
    Journal of chemical information and modeling, 2018, 08-27, Volume: 58, Issue:8

    Topics: Algorithms; Analgesics; Binding Sites; Calcium Channels; Cryoelectron Microscopy; Gabapentin; Humans; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Pregabalin; Protein Binding

2018
Gabepentinoids and Benzodiazepines in Medicare Part D.
    Journal of the American Society of Nephrology : JASN, 2018, Volume: 29, Issue:11

    Topics: Aged; Amines; Benzodiazepines; Gabapentin; Humans; Medicare; Pregabalin; Renal Dialysis; United States

2018
Authors' Reply.
    Journal of the American Society of Nephrology : JASN, 2018, Volume: 29, Issue:11

    Topics: Amines; Gabapentin; Humans; Pregabalin; Renal Dialysis

2018
Up-date on Clinical Management of Postherpetic Neuralgia and Mechanism-Based Treatment: New Options in Therapy.
    The Journal of infectious diseases, 2018, 09-22, Volume: 218, Issue:suppl_2

    Topics: Acetylcholine Release Inhibitors; Analgesics; Antidepressive Agents, Tricyclic; Botulinum Toxins, Type A; Capsaicin; Cohort Studies; Data Interpretation, Statistical; Gabapentin; Humans; Neuralgia, Postherpetic; Pregabalin; Sensory System Agents

2018
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Method to Quantify Gabapentin and Pregabalin in Urine.
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1872

    Topics: Anticonvulsants; Chromatography, Liquid; Gabapentin; Humans; Pain Management; Pregabalin; Tandem Mass Spectrometry

2019
Extremely large outlier treatment effects may be a footprint of bias in trials from less developed countries: randomized trials of gabapentinoids.
    Journal of clinical epidemiology, 2019, Volume: 106

    Topics: Bias; Conflict of Interest; Developing Countries; Gabapentin; Humans; Meta-Analysis as Topic; Pregabalin; Randomized Controlled Trials as Topic

2019
Change in Pain Score after Administration of Analgesics for Lower Extremity Fracture Pain during Hospitalization.
    Pain management nursing : official journal of the American Society of Pain Management Nurses, 2019, Volume: 20, Issue:2

    Topics: Adult; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents; Baclofen; Bones of Lower Extremity; Cohort Studies; Duloxetine Hydrochloride; Female; Fractures, Bone; Gabapentin; Hospitalization; Humans; Male; Middle Aged; Muscle Relaxants, Central; Pain Management; Pain Measurement; Pregabalin; Retrospective Studies

2019
Trends in First Gabapentin and Pregabalin Prescriptions in Primary Care in the United Kingdom, 1993-2017.
    JAMA, 2018, 11-27, Volume: 320, Issue:20

    Topics: Analgesics; Analgesics, Opioid; Anticonvulsants; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization; Gabapentin; Humans; Off-Label Use; Pregabalin; Primary Health Care; United Kingdom

2018
Need for international classification of gabapentin as a controlled substance.
    BMJ (Clinical research ed.), 2018, 11-29, Volume: 363

    Topics: Controlled Substances; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Pregabalin

2018
Using time series analysis approaches for improved prediction of pain outcomes in subgroups of patients with painful diabetic peripheral neuropathy.
    PloS one, 2018, Volume: 13, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Biomarkers; Cluster Analysis; Computer Simulation; Diabetic Neuropathies; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Interrupted Time Series Analysis; Male; Middle Aged; Neuralgia; Pain; Pain Measurement; Predictive Value of Tests; Pregabalin; Treatment Outcome

2018
Perioperative use of gabapentinoids for the management of postoperative acute pain: protocol of a systematic review and meta-analysis.
    Systematic reviews, 2019, 01-16, Volume: 8, Issue:1

    Topics: Acute Pain; Analgesics; Gabapentin; Humans; Meta-Analysis as Topic; Pain, Postoperative; Perioperative Care; Pregabalin; Randomized Controlled Trials as Topic; Research Design; Risk Assessment; Systematic Reviews as Topic

2019
Actigraphy-based evaluation of sleep quality and physical activity in individuals with spinal cord injury.
    Spinal cord series and cases, 2019, Volume: 5

    Topics: Actigraphy; Adult; Analgesics; Benzodiazepines; Case-Control Studies; Exercise; Female; Gabapentin; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Paraplegia; Pregabalin; Sleep; Sleep Latency; Sleep Wake Disorders; Sleepiness; Spinal Cord Injuries

2019
Patterns of gabapentin and pregabalin use and misuse: Results of a population-based cohort study in France.
    British journal of clinical pharmacology, 2019, Volume: 85, Issue:6

    Topics: Adult; Aged; Drug Prescriptions; Drug Utilization; Female; France; Gabapentin; Humans; Incidence; Male; Middle Aged; Practice Patterns, Physicians'; Pregabalin; Prescription Drug Misuse; Retrospective Studies; Risk Assessment; Risk Factors; Substance-Related Disorders

2019
Switching from gabapentin to pregabalin.
    The New Zealand medical journal, 2019, 03-08, Volume: 132, Issue:1491

    Topics: Analgesics; Anticonvulsants; Drug Substitution; Gabapentin; Humans; Neuralgia; New Zealand; Pregabalin

2019
Falling Dominoes.
    Anesthesia and analgesia, 2019, Volume: 128, Issue:4

    Topics: Accidental Falls; Adolescent; Child; Gabapentin; Humans; Pain; Pregabalin

2019
Prescribing practice of pregabalin/gabapentin in pain therapy: an evaluation of German claim data.
    BMJ open, 2019, 03-30, Volume: 9, Issue:3

    Topics: Adult; Aged; Analgesics; Chronic Pain; Female; Gabapentin; Germany; Humans; Infant; Insurance Claim Review; Male; Neuralgia; Pain Management; Practice Patterns, Physicians'; Pregabalin; Primary Health Care; Withholding Treatment

2019
Association 'Between Gabapentinoids on the Day of Colorectal Surgery and Adverse Postoperative Respiratory Outcomes.
    Annals of surgery, 2019, Volume: 270, Issue:6

    Topics: Adult; Analgesics; Colon; Digestive System Surgical Procedures; Elective Surgical Procedures; Female; Gabapentin; Humans; Length of Stay; Male; Morphine; Postoperative Complications; Pregabalin; Rectum; Respiration, Artificial; Retrospective Studies

2019
Proper or Improper Use of the Crossover Design in Clinical Trials in Chronic Sciatica?
    JAMA neurology, 2019, 06-01, Volume: 76, Issue:6

    Topics: Adult; Cross-Over Studies; Gabapentin; Humans; Low Back Pain; Pregabalin; Sciatica

2019
Proper or Improper Use of the Crossover Design in Clinical Trials in Chronic Sciatica?-Reply.
    JAMA neurology, 2019, 06-01, Volume: 76, Issue:6

    Topics: Adult; Cross-Over Studies; Gabapentin; Humans; Low Back Pain; Pregabalin; Sciatica

2019
Misuse and Mortality Related to Gabapentin and Pregabalin are Being Under-Estimated: A Two-Year Post-Mortem Population Study.
    Journal of analytical toxicology, 2019, Aug-23, Volume: 43, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; England; Female; Forensic Toxicology; Gabapentin; Heroin Dependence; Humans; Incidence; Male; Middle Aged; Pregabalin; Prevalence; Substance-Related Disorders

2019
Associations between gabapentinoids and suicidal behaviour, unintentional overdoses, injuries, road traffic incidents, and violent crime: population based cohort study in Sweden.
    BMJ (Clinical research ed.), 2019, 06-12, Volume: 365

    Topics: Accidents, Traffic; Adult; Aged; Drug Overdose; Drug Prescriptions; Female; Follow-Up Studies; Gabapentin; Humans; Male; Middle Aged; Pregabalin; Prescription Drugs; Risk Factors; Suicide; Sweden; Violence; Wounds and Injuries; Young Adult

2019
Oral Gabapentinoids and Nerve Blocks for the Treatment of Chronic Ocular Pain.
    Eye & contact lens, 2020, Volume: 46, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics; Anesthetics, Local; Bupivacaine; Chronic Pain; Drug Combinations; Eye Pain; Female; Gabapentin; Humans; Male; Methylprednisolone Acetate; Middle Aged; Nerve Block; Ophthalmic Nerve; Pain Management; Pregabalin; Retrospective Studies; Young Adult

2020
Commentary on "A Call for Caution in Prescribing Gabapentin to Individuals with Concurrent Polysubstance Abuse: A Case Report".
    Journal of psychiatric practice, 2019, Volume: 25, Issue:4

    Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin

2019
Reports of gabapentin and pregabalin abuse, misuse, dependence, or overdose: An analysis of the Food And Drug Administration Adverse Events Reporting System (FAERS).
    Research in social & administrative pharmacy : RSAP, 2019, Volume: 15, Issue:8

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Analgesics; Anticonvulsants; Databases, Factual; Drug Overdose; Female; Gabapentin; Humans; Male; Middle Aged; Pharmacovigilance; Pregabalin; Substance-Related Disorders; United States; United States Food and Drug Administration; Young Adult

2019
Association of Gabapentin or Pregabalin Use and Incidence of Acute Angle-closure Glaucoma.
    Journal of glaucoma, 2019, Volume: 28, Issue:9

    Topics: Acute Disease; Adult; Analgesics; Case-Control Studies; Female; Gabapentin; Glaucoma, Angle-Closure; Humans; Incidence; Intraocular Pressure; Male; Middle Aged; Pregabalin

2019
Acute effect of cannabidiol on the activity of various novel antiepileptic drugs in the maximal electroshock- and 6 Hz-induced seizures in mice: Pharmacodynamic and pharmacokinetic studies.
    Neuropharmacology, 2019, 11-01, Volume: 158

    Topics: Animals; Anticonvulsants; Brain; Cannabidiol; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Interactions; Drug Resistant Epilepsy; Electric Stimulation; Gabapentin; Lacosamide; Lamotrigine; Levetiracetam; Male; Mice; Oxcarbazepine; Pregabalin; Seizures; Tiagabine; Topiramate

2019
Validation of a High-throughput Screening and Quantification Method for the Determination of Gabapentinoids in Blood Using a Combination of LC-TOF-MS and LC-MS-MS.
    Journal of analytical toxicology, 2019, Oct-17, Volume: 43, Issue:9

    Topics: Autopsy; Chromatography, High Pressure Liquid; Chromatography, Liquid; Gabapentin; Humans; Limit of Detection; Methanol; Pregabalin; Tandem Mass Spectrometry

2019
Parkinsonism associated with gabapentinoid drugs: A pharmacoepidemiologic study.
    Movement disorders : official journal of the Movement Disorder Society, 2020, Volume: 35, Issue:1

    Topics: Aged; Bayes Theorem; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Parkinsonian Disorders; Pharmaceutical Preparations; Pregabalin

2020
The effect of gabapentin and pregabalin on bone turnover and bone strength: A prospective study in Wistar rats.
    Pharmacological reports : PR, 2019, Volume: 71, Issue:6

    Topics: Absorptiometry, Photon; Alkaline Phosphatase; Animals; Anticonvulsants; Biomechanical Phenomena; Bone Density; Bone Remodeling; Femur; Gabapentin; Male; Orchiectomy; Osteoprotegerin; Pregabalin; Prospective Studies; Rats; Rats, Wistar

2019
Management of pregabalin and gabapentin prescribing and use in NSW prisons.
    The Medical journal of Australia, 2019, Volume: 211, Issue:10

    Topics: Ambulances; Gabapentin; Humans; Pregabalin; Prescription Drug Misuse; Prisons

2019
Gabapentin drug misuse signals: A pharmacovigilance assessment using the FDA adverse event reporting system.
    Drug and alcohol dependence, 2020, 01-01, Volume: 206

    Topics: Adverse Drug Reaction Reporting Systems; Bayes Theorem; Databases, Factual; Duloxetine Hydrochloride; Gabapentin; Humans; Pharmacovigilance; Pregabalin; Risk Factors; Substance-Related Disorders; United States; United States Food and Drug Administration

2020
Gabapentinoids for Pain: Potential Unintended Consequences.
    American family physician, 2019, 12-01, Volume: 100, Issue:11

    Topics: Analgesics; Chronic Pain; Drug Misuse; Gabapentin; Humans; Pain; Practice Guidelines as Topic; Pregabalin

2019
Dose-Dependent Association of Gabapentinoids with Pulmonary Complications After Total Hip and Knee Arthroplasties.
    The Journal of bone and joint surgery. American volume, 2020, Feb-05, Volume: 102, Issue:3

    Topics: Adult; Aged; Analgesics; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Female; Gabapentin; Humans; Lung Diseases; Male; Middle Aged; Postoperative Complications; Pregabalin; Regression Analysis; Retrospective Studies; United States

2020
An Insight into Gabapentin and Pregabalin in Scottish Prisoners.
    Journal of analytical toxicology, 2020, Apr-02, Volume: 44, Issue:5

    Topics: Female; Gabapentin; Humans; Male; Pregabalin; Prisoners; Scotland; Substance Abuse Detection; Substance-Related Disorders

2020
Effects of gabapentinoids on responses of primary cultures from rat dorsal root ganglia to inflammatory or somatosensory stimuli.
    Journal of basic and clinical physiology and pharmacology, 2020, Feb-20, Volume: 31, Issue:4

    Topics: Analgesics; Animals; Capsaicin; Female; Gabapentin; Ganglia, Spinal; Inflammation; Lipopolysaccharides; Male; Neuralgia; Neurons; Pregabalin; Primary Cell Culture; Rats; Rats, Wistar; Sensory System Agents; Somatosensory Cortex

2020
New Warning for Gabapentinoids.
    The American journal of nursing, 2020, Volume: 120, Issue:4

    Topics: Analgesics; Drug Interactions; Gabapentin; Humans; Pregabalin

2020
Concomitant Use of Gabapentinoids with Opioids Is Associated with Increased Mortality and Morbidity among Dialysis Patients.
    American journal of nephrology, 2020, Volume: 51, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Cause of Death; Drug Prescriptions; Female; Gabapentin; Hospitalization; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pain; Polypharmacy; Pregabalin; Registries; Renal Dialysis; Retrospective Studies; Risk Assessment; United States; Young Adult

2020
Drug Repositioning: Antimalarial Activities of GABA Analogs in Mice Infected with
    Central nervous system agents in medicinal chemistry, 2020, Volume: 20, Issue:2

    Topics: Animals; Antimalarials; Drug Repositioning; Female; Gabapentin; gamma-Aminobutyric Acid; Malaria; Male; Mice; Plasmodium berghei; Pregabalin

2020
In brief: Respiratory depression with gabapentinoids.
    The Medical letter on drugs and therapeutics, 2020, Jun-01, Volume: 62, Issue:1599

    Topics: Analgesics; Gabapentin; Humans; Pregabalin; Respiratory Insufficiency

2020
Trends in gabapentinoid prescribing, co-prescribing of opioids and benzodiazepines, and associated deaths in Scotland.
    British journal of anaesthesia, 2020, Volume: 125, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Benzodiazepines; Child; Child, Preschool; Drug Overdose; Drug Therapy, Combination; Female; Gabapentin; Humans; Infant; Male; Middle Aged; Practice Patterns, Physicians'; Pregabalin; Scotland; Sex Factors; Young Adult

2020
Perioperative Gabapentinoids: Deflating the Bubble.
    Anesthesiology, 2020, Volume: 133, Issue:2

    Topics: Analgesics; Ataxia; Dizziness; Gabapentin; Humans; Pain, Postoperative; Pregabalin; Preoperative Care

2020
Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis.
    Anesthesiology, 2020, Volume: 133, Issue:2

    Topics: Acute Pain; Adult; Analgesics; Gabapentin; Humans; Pain, Postoperative; Pregabalin

2020
Improvement of sleep quality after treatment in patients with lumbar spinal stenosis: a prospective comparative study between conservative versus surgical treatment.
    Scientific reports, 2020, 08-24, Volume: 10, Issue:1

    Topics: Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Conservative Treatment; Decompression, Surgical; Depression; Female; Gabapentin; Humans; Lumbar Vertebrae; Male; Pregabalin; Propensity Score; Prospective Studies; Sleep; Sleep Aids, Pharmaceutical; Sleep Wake Disorders; Spinal Stenosis; Surveys and Questionnaires; Treatment Outcome

2020
Comparing Effectiveness of Gabapentin and Pregabalin in Treatment of Neuropathic Pain: A Retrospective Cohort of Palliative Care Outpatients.
    Journal of pain & palliative care pharmacotherapy, 2020, Volume: 34, Issue:4

    Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; Humans; Neuralgia; Outpatients; Palliative Care; Pregabalin; Retrospective Studies

2020
Pain management in patients with end-stage renal disease and calciphylaxis- a survey of clinical practices among physicians.
    BMC nephrology, 2020, 09-18, Volume: 21, Issue:1

    Topics: Acetaminophen; Advance Care Planning; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Breakthrough Pain; Calciphylaxis; Gabapentin; Humans; Kidney Failure, Chronic; Nephrology; Pain; Pain Management; Pain, Procedural; Palliative Medicine; Practice Patterns, Physicians'; Pregabalin; Referral and Consultation; Surveys and Questionnaires; United Kingdom

2020
Baclofen: To Screen or Not to Screen in Postmortem Blood?
    Journal of analytical toxicology, 2021, Jul-10, Volume: 45, Issue:6

    Topics: Autopsy; Baclofen; Gabapentin; Humans; Pregabalin; Substance-Related Disorders

2021
Co-prescription of gabapentinoids and opioids among adults with and without osteoarthritis in the United Kingdom between 1995 and 2017.
    Rheumatology (Oxford, England), 2021, 04-06, Volume: 60, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analgesics, Opioid; Drug Therapy, Combination; Female; Gabapentin; Humans; Male; Middle Aged; Osteoarthritis; Practice Patterns, Physicians'; Pregabalin; Sex Factors; United Kingdom

2021
Antidepressant and anticonvulsant prescription rates in patients with osteoarthritis: a population-based cohort study.
    Rheumatology (Oxford, England), 2021, 05-14, Volume: 60, Issue:5

    Topics: Aged; Analgesics; Anticonvulsants; Antidepressive Agents; Depressive Disorder; Drug Prescriptions; Female; Gabapentin; Humans; Male; Middle Aged; Osteoarthritis; Practice Patterns, Physicians'; Pregabalin

2021
Gabapentinoid and Opioid Utilization and Cost Trends Among Injured Workers.
    Journal of occupational and environmental medicine, 2021, 02-01, Volume: 63, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Gabapentin; Humans; Pregabalin; Workers' Compensation

2021
Gabapentinoid misuse, abuse and non-prescribed obtainment in a United States general population sample.
    International journal of clinical pharmacy, 2021, Volume: 43, Issue:4

    Topics: Analgesics, Opioid; Cross-Sectional Studies; Gabapentin; Humans; Pregabalin; Risk Factors; United States

2021
Trends in new prescription of gabapentinoids and of coprescription with opioids in the 4 nations of the UK, 1993-2017.
    British journal of clinical pharmacology, 2021, Volume: 87, Issue:8

    Topics: Analgesics, Opioid; Drug Prescriptions; Gabapentin; Humans; Pregabalin; United Kingdom

2021
Prevention, diagnosis and management of chemotherapy-induced peripheral neuropathy: a cross-sectional study of French oncologists' professional practices.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021, Volume: 29, Issue:7

    Topics: Adult; Amitriptyline; Antineoplastic Agents; Calcium; Cross-Sectional Studies; Duloxetine Hydrochloride; France; Gabapentin; Humans; Magnesium; Male; Middle Aged; Neurotoxicity Syndromes; Oncologists; Peripheral Nervous System Diseases; Practice Patterns, Physicians'; Pregabalin; Surveys and Questionnaires; Vitamins

2021
A Retrospective Analysis of Gabapentinoid and Opioids to Opioid Monotherapy for Pain Relief in Patients with Chronic Neck and Low Back Pain.
    Pain medicine (Malden, Mass.), 2021, 08-06, Volume: 22, Issue:8

    Topics: Analgesics, Opioid; Gabapentin; Humans; Low Back Pain; Pregabalin; Retrospective Studies

2021
Prevalence of and Factors Associated with Gabapentinoid Use and Misuse Among Texas Medicaid Recipients.
    Clinical drug investigation, 2021, Volume: 41, Issue:3

    Topics: Adolescent; Adult; Analgesics, Opioid; Female; Gabapentin; Humans; Male; Medicaid; Middle Aged; Neuralgia; Opioid-Related Disorders; Pregabalin; Prevalence; Retrospective Studies; Texas; United States; Young Adult

2021
What Is the Mechanism of Therapeutic and Adverse Effects of Gabapentinoids?
    Neurology, 2021, 02-16, Volume: 96, Issue:7

    Topics: Analgesics; Calcium Channels; Gabapentin; Humans; Neurons; Pregabalin

2021
Association of gabapentinoid utilization with postoperative pulmonary complications in gynecologic surgery: a retrospective cohort study.
    Current medical research and opinion, 2021, Volume: 37, Issue:5

    Topics: Adult; Analgesics, Opioid; Female; Gabapentin; Gynecologic Surgical Procedures; Humans; Postoperative Complications; Pregabalin; Retrospective Studies

2021
Respiratory concerns of gabapentin and pregabalin: What does it mean to the pharmacovigilance systems in developing countries?
    F1000Research, 2020, Volume: 9

    Topics: Analgesics; Developing Countries; Gabapentin; Humans; Pharmacovigilance; Pregabalin; Respiratory Insufficiency; United States

2020
Comment on "Abuse and Misuse of Pregabalin and Gabapentin: A Systematic Review Update".
    Drugs, 2021, Volume: 81, Issue:5

    Topics: Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin

2021
Authors' Reply to Bonnet et al. "Abuse and Misuse of Pregabalin and Gabapentin: A Systematic Review Update".
    Drugs, 2021, Volume: 81, Issue:5

    Topics: Amines; Gabapentin; Humans; Pregabalin; Substance-Related Disorders

2021
Should gabapentinoids be prescribed long-term for anxiety and other mental health conditions?
    Addictive behaviors, 2021, Volume: 119

    Topics: Anxiety; England; Gabapentin; Humans; Mental Health; Pregabalin

2021
Pregabalin and gabapentin in non-opioid poisoning deaths.
    Forensic science international, 2021, Volume: 324

    Topics: Accidents; Adult; Aged; Aged, 80 and over; Analgesics; Chromatography, Liquid; Drug Overdose; Female; Finland; Forensic Toxicology; Gabapentin; Humans; Male; Mass Spectrometry; Middle Aged; Pregabalin; Retrospective Studies; Suicide, Completed

2021
Toxicity assessment of concurrent gabapentin/pregabalin administration with high-dose melphalan in autologous hematopoietic cell transplant recipients.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021, Volume: 29, Issue:12

    Topics: Gabapentin; Hematopoietic Stem Cell Transplantation; Humans; Melphalan; Multiple Myeloma; Pregabalin; Prospective Studies; Retrospective Studies; Transplant Recipients; Transplantation Conditioning; Transplantation, Autologous

2021
Do we still need gabapentinoids in anaesthesia?
    Anaesthesia, critical care & pain medicine, 2021, Volume: 40, Issue:4

    Topics: Anesthesia; Gabapentin; Humans; Pregabalin

2021
Trends in Gabapentin and Pregabalin Prescribing in a Tertiary Pediatric Medical Center.
    Hospital pediatrics, 2021, Volume: 11, Issue:8

    Topics: Adult; Analgesics; Analgesics, Opioid; Child; Gabapentin; Hospitals; Humans; Pediatrics; Pregabalin; Retrospective Studies

2021
Characteristics of fatal gabapentinoid-related poisoning in Australia, 2000-2020.
    Clinical toxicology (Philadelphia, Pa.), 2022, Volume: 60, Issue:3

    Topics: Analgesics, Opioid; Drug Overdose; Female; Gabapentin; Humans; Male; Middle Aged; Pregabalin; Retrospective Studies

2022
Gabapentinoid Dosing and Associated Toxicities in Patients With or Without Concomitant Opioids During Hospitalization.
    The American journal of hospice & palliative care, 2022, Volume: 39, Issue:5

    Topics: Adult; Analgesics; Analgesics, Opioid; Gabapentin; Hospitalization; Humans; Pain; Pregabalin

2022
Biotransformation of pregabalin in surface water matrices and the occurrence of transformation products in the aquatic environment - comparison to the structurally related gabapentin.
    Water research, 2021, Sep-15, Volume: 203

    Topics: Biotransformation; Gabapentin; Pregabalin; Rivers; Wastewater; Water; Water Pollutants, Chemical

2021
Gabapentinoid use in French most precarious populations: Insight from Lyon Permanent Access to Healthcare (PASS) units, 2016-1Q2021.
    Fundamental & clinical pharmacology, 2022, Volume: 36, Issue:2

    Topics: Analgesics; Analgesics, Opioid; Chronic Pain; Delivery of Health Care; Gabapentin; Humans; Pregabalin

2022
Gabapentinoids: When Is the Right Moment to Stop?
    Anesthesia and analgesia, 2021, 11-01, Volume: 133, Issue:5

    Topics: Gabapentin; Pregabalin

2021
Heme oxygenase-1 in the spinal cord plays crucial roles in the analgesic effects of pregabalin and gabapentin in a spared nerve-injury mouse model.
    Neuroscience letters, 2022, 01-10, Volume: 767

    Topics: Analgesics; Animals; Disease Models, Animal; Gabapentin; Heme Oxygenase-1; Male; Mice; Mice, Inbred C57BL; Neuralgia; Pregabalin; Sciatic Nerve; Spinal Cord

2022
Risk of Pregabalin-Induced Hypoglycemia: Analysis of the Japanese Adverse Drug Event Report Database.
    Journal of clinical pharmacology, 2022, Volume: 62, Issue:6

    Topics: Aged; Drug-Related Side Effects and Adverse Reactions; Duloxetine Hydrochloride; Gabapentin; Humans; Hypoglycemia; Japan; Neuralgia; Pregabalin

2022
Higher-Dose Gabapentinoids and the Risk of Adverse Events in Older Adults With CKD: A Population-Based Cohort Study.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2022, Volume: 80, Issue:1

    Topics: Aged; Aged, 80 and over; Brain Diseases; Cohort Studies; Female; Gabapentin; Humans; Male; Ontario; Pregabalin; Renal Insufficiency, Chronic; Respiratory Insufficiency

2022
The impact of regulatory restrictions on pregabalin use in Saudi Arabia: An interrupted time series analysis.
    Pharmacoepidemiology and drug safety, 2022, Volume: 31, Issue:5

    Topics: Analgesics; Gabapentin; Humans; Interrupted Time Series Analysis; Neuralgia; Pregabalin; Saudi Arabia

2022
Misuse of gabapentinoids (pregabalin and gabapentin) in patients with neuropathic pain related to spinal cord injury.
    The journal of spinal cord medicine, 2023, Volume: 46, Issue:5

    Topics: Amines; Analgesics; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pregabalin; Spinal Cord Injuries

2023
Gabapentinoid Prescribing for Carpal Tunnel Syndrome.
    Hand (New York, N.Y.), 2023, Volume: 18, Issue:1_suppl

    Topics: Carpal Tunnel Syndrome; Cohort Studies; Gabapentin; Humans; Pregabalin; Retrospective Studies

2023
Simultaneous quantitative analysis of 39 common toxicological drugs for increased efficiency in an ante- and postmortem laboratory.
    Forensic science international, 2022, Volume: 334

    Topics: Baclofen; Chromatography, High Pressure Liquid; Forensic Toxicology; Gabapentin; Pregabalin; Reproducibility of Results

2022
Gabapentinoid-induced peripheral edema and acute heart failure: A translational study combining pharmacovigilance data and in vitro animal experiments.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 149

    Topics: Aged; Aged, 80 and over; Animal Experimentation; Animals; Edema; Female; Gabapentin; Heart Failure; Humans; Male; Middle Aged; Pharmacovigilance; Pregabalin; Rats

2022
Fatalities associated with gabapentinoids in England (2004-2020).
    British journal of clinical pharmacology, 2022, Volume: 88, Issue:8

    Topics: Analgesics, Opioid; England; Gabapentin; Humans; Pregabalin; Substance-Related Disorders

2022
Prevalence of Gabapentinoids and Central Nervous System Depressant Drugs, and Their Association with Risk Factors for Respiratory Depression in Primary Care Patients.
    Clinical drug investigation, 2022, Volume: 42, Issue:5

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Anxiety Agents; Cross-Sectional Studies; Female; Gabapentin; Humans; Hypnotics and Sedatives; Male; Pregabalin; Prevalence; Primary Health Care; Respiratory Insufficiency; Risk Factors

2022
Avoid prescribing pregabalin during pregnancy if possible, says UK drug regulator.
    BMJ (Clinical research ed.), 2022, 04-21, Volume: 377

    Topics: Analgesics; Female; Gabapentin; Humans; Practice Patterns, Physicians'; Pregabalin; Pregnancy; United Kingdom

2022
Gabapentinoids: repeating mistakes of the past?
    Addiction (Abingdon, England), 2022, Volume: 117, Issue:12

    Topics: Gabapentin; Humans; Pregabalin

2022
Non-prescribed use of gabapentinoids: Mechanisms, predisposing factors, associated hazards and clinical management.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2022, Volume: 63

    Topics: Analgesics; Analgesics, Opioid; Causality; Gabapentin; Pregabalin

2022
Comparing the therapeutic effects of pregabalin and gabapentin after transforaminal epidural nerve block in lumbar radiculopathy.
    Medicine, 2022, Aug-12, Volume: 101, Issue:32

    Topics: Gabapentin; Humans; Injections, Epidural; Low Back Pain; Lumbar Vertebrae; Nerve Block; Pregabalin; Radiculopathy; Steroids; Treatment Outcome

2022
Cardiovascular risk of gabapentin and pregabalin in patients with diabetic neuropathy.
    Cardiovascular diabetology, 2022, 09-01, Volume: 21, Issue:1

    Topics: Amines; Analgesics; Cardiovascular Diseases; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Heart Disease Risk Factors; Heart Failure; Humans; Myocardial Infarction; Pain; Peripheral Vascular Diseases; Pregabalin; Pulmonary Embolism; Retrospective Studies; Risk Factors; Stroke

2022
Association between anti-seizure medication and the risk of lower urinary tract infection in patients with epilepsy.
    Epilepsy & behavior : E&B, 2022, Volume: 135

    Topics: Adult; Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Epilepsy; Female; Gabapentin; Humans; Male; Pregabalin; Retrospective Studies; Urinary Tract Infections; Valproic Acid

2022
A Case Illustrating the Practical Application of the AAOS Clinical Practice Guideline: Pharmacologic, Physical, and Cognitive Pain Alleviation for Musculoskeletal Extremity/Pelvis Surgery.
    The Journal of the American Academy of Orthopaedic Surgeons, 2022, Sep-15, Volume: 30, Issue:18

    Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cognition; Cyclooxygenase 2; Extremities; Gabapentin; Humans; Ketamine; Orthopedic Procedures; Pain Measurement; Pain, Postoperative; Pelvis; Pregabalin

2022
Opioid and gabapentinoid prescriptions in England from 2015 to 2020.
    PloS one, 2022, Volume: 17, Issue:11

    Topics: Analgesics, Opioid; England; Gabapentin; Pregabalin; Prescriptions

2022
A simple and easy non-derivatization gas chromatography-mass spectrometry method for simultaneous quantification of valproic acid, gabapentin, pregabalin, and vigabatrin in human plasma.
    Journal of separation science, 2023, Volume: 46, Issue:2

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Pregabalin; Valproic Acid; Vigabatrin

2023
Case Series: Synergistic Effect of Gabapentin and Adjuvant Pregabalin in Neuropathic Pain.
    Journal of pain & palliative care pharmacotherapy, 2023, Volume: 37, Issue:1

    Topics: Amines; Analgesics; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; Humans; Neuralgia; Pregabalin; Quality of Life; Rats

2023
The risk of fragility fractures following initiation of gabapentin and pregabalin-A Danish, nationwide, high-dimensional propensity score-matched cohort study.
    Basic & clinical pharmacology & toxicology, 2023, Volume: 132, Issue:5

    Topics: Adult; Amines; Analgesics; Cohort Studies; Cyclohexanecarboxylic Acids; Denmark; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pregabalin; Propensity Score

2023
[Off-label use of gabapentinoid drugs: is it necessary a deprescription strategy?]
    Gaceta sanitaria, 2023, Volume: 37

    Topics: Analgesics, Opioid; Deprescriptions; Gabapentin; Humans; Off-Label Use; Pregabalin; Retrospective Studies

2023
Risk of parkinsonism and related movement disorders with gabapentinoids or tramadol: A case-crossover study.
    Pharmacotherapy, 2023, Volume: 43, Issue:2

    Topics: Analgesics, Opioid; Cross-Over Studies; Gabapentin; Humans; Parkinsonian Disorders; Pregabalin; Tramadol

2023
Characterization of Outpatient Gabapentinoid Prescribing for Pain.
    Journal of pain & palliative care pharmacotherapy, 2023, Volume: 37, Issue:2

    Topics: Adult; Amines; Analgesics; Gabapentin; Humans; Outpatients; Pain; Pregabalin; Retrospective Studies

2023
Channeling of New Neuropsychiatric Drugs-Impact on Safety and Effectiveness Studies.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2023, Volume: 20, Issue:2

    Topics: Adult; Cross-Sectional Studies; Diabetic Neuropathies; Epilepsy; Gabapentin; Humans; Levetiracetam; Parkinson Disease; Pregabalin; Quetiapine Fumarate

2023
[Medical Treatment of Chronic Pain].
    Brain and nerve = Shinkei kenkyu no shinpo, 2023, Volume: 75, Issue:3

    Topics: Analgesics; Chronic Pain; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; Humans; Pregabalin

2023
Rescheduling gabapentinoids had negligible effects on prescribing behaviour by general practitioners in England.
    Pharmacoepidemiology and drug safety, 2023, Volume: 32, Issue:8

    Topics: England; Gabapentin; General Practitioners; Humans; Pregabalin

2023
Abuse and addiction in gabapentinoid drug users for neuropathic pain.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:12

    Topics: Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Drug Users; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pregabalin

2023
"We were all looking for the magic pill": A qualitative study of patient experiences using gabapentinoids for chronic pain.
    The International journal on drug policy, 2023, Volume: 119

    Topics: Adult; Chronic Pain; Gabapentin; Humans; Patient Outcome Assessment; Pregabalin; Qualitative Research

2023
Quantification of Gabapentin, Lacosamide, Perampanel, Pregabalin, Rufinamide, and Vigabatrin in Serum Using Liquid Chromatography-Tandem Mass Spectrometry.
    Methods in molecular biology (Clifton, N.J.), 2024, Volume: 2737

    Topics: Anticonvulsants; Chromatography, Liquid; Gabapentin; Lacosamide; Pregabalin; Tandem Mass Spectrometry; Vigabatrin

2024