gabapentin and mibefradil

gabapentin has been researched along with mibefradil in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's9 (90.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Campillo, NE; Guerra, A; Páez, JA1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Back, SK; Choo, HY; Kam, YL; Na, HS; Rhee, HK; Rhim, H1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chung, HJ; Lee, YS; Pae, AN; Roh, EJ; Seo, SH; Shin, KJ; Song, CM; Woo, HM1
Chung, H; Keum, G; Kim, JH; Nam, G1
Kim, JH; Nam, G1
Jeong, KS; Lim, SM; Pae, AN; Son, WS1

Other Studies

10 other study(ies) available for gabapentin and mibefradil

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Synthesis and T-type calcium channel blocking activity of novel diphenylpiperazine compounds, and evaluation of in vivo analgesic activity.
    Bioorganic & medicinal chemistry, 2010, Aug-15, Volume: 18, Issue:16

    Topics: Analgesics; Animals; Calcium Channels, T-Type; Humans; Neuralgia; Pain Measurement; Piperazines; Rats

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Synthesis and biological evaluation of 4-piperidinecarboxylate and 4-piperidinecyanide derivatives for T-type calcium channel blockers.
    Bioorganic & medicinal chemistry letters, 2011, Oct-01, Volume: 21, Issue:19

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Drug Stability; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Hyperalgesia; Inhibitory Concentration 50; Ligands; Mibefradil; Molecular Structure; Molecular Targeted Therapy; Neuralgia; Patch-Clamp Techniques; Piperidines; Quantitative Structure-Activity Relationship; Rats; Spinal Nerves; Structure-Activity Relationship

2011
Synthesis and T-type calcium channel-blocking effects of aryl(1,5-disubstituted-pyrazol-3-yl)methyl sulfonamides for neuropathic pain treatment.
    European journal of medicinal chemistry, 2016, Nov-10, Volume: 123

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Chemistry Techniques, Synthetic; Drug Stability; Humans; Neuralgia; Rats; Sulfonamides

2016
Synthesis and evaluation of 6-pyrazoylamido-3N-substituted azabicyclo[3,1,0]hexane derivatives as T-type calcium channel inhibitors for treatment of neuropathic pain.
    Bioorganic & medicinal chemistry, 2016, 11-01, Volume: 24, Issue:21

    Topics: Administration, Oral; Animals; Azabicyclo Compounds; Calcium Channel Blockers; Calcium Channels, T-Type; Disease Models, Animal; HEK293 Cells; Humans; Male; Neuralgia; Pyrazoles; Rats; Structure-Activity Relationship

2016
Structural hybridization of pyrrolidine-based T-type calcium channel inhibitors and exploration of their analgesic effects in a neuropathic pain model.
    Bioorganic & medicinal chemistry letters, 2019, 05-15, Volume: 29, Issue:10

    Topics: Analgesics; Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Calcium Signaling; Disease Models, Animal; Gabapentin; Ganglia, Spinal; Humans; Ligation; Microsomes, Liver; Molecular Structure; Neuralgia; Pyrrolidines; Rats; Structure-Activity Relationship

2019