gabapentin and indomethacin

gabapentin has been researched along with indomethacin in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's16 (45.71)29.6817
2010's19 (54.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jolivette, LJ; Ward, KW1
Jolivette, LJ; Nagilla, R; Ward, KW1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Gangadhar, M; Karthick, S; Mallipeddi, S; Samala, G; Semwal, A; Sharma, M; Sriram, D; Yogeeswari, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Alcantara, MC; Bordini, CA; Mariano Da Silva, H; Speciali, JG1
Boulet, J; Gottshall, S; Harrison, J; Mark, L; Pearson, M; Walker, K; Whiteside, GT1
Boulet, JM; Chaffer, SM; Elsemore, DA; Gottshall, SL; Harrison, JE; Koetzner, L; Lee, G; Mark, L; Miller, W; Pearson, MS; Rabadi, L; Rotshteyn, Y; Shan, S; Tafesse, L; Toth, M; Turchin, PI; Valenzano, KJ; Whiteside, GT1
Mainardi, F; Perego, G; Trucco, M; Zanchin, G1
Bosch, EP; Boulton, P; Dodick, DW; Purdy, RA1
Cohen, AS1
Cohen, AS; Goadsby, PJ1
Spears, RC1
Cummons, TA; Harrison, JE; Leventhal, L; Lu, P; Piesla, MJ; Strassle, BW; Whiteside, GT1
Ferrante, E; Lisotto, C; Nappi, G; Rossi, P; Tassorelli, C1
Antonialli, CS; Cechinel Filho, V; Cicció, JF; da Silva, GF; Quintão, NL; Rocha, LW1
Allena, M; Ferrante, E; Lisotto, C; Nappi, G; Rossi, P; Tassorelli, C1
Kato, A; Ogawa, K; Shinohara, S; Takasu, K; Yoneda, Y1
Calixto, JB; Costa, R; Manjavachi, MN; Quintão, NL1
Doods, H; Gould, SA; Lamla, T; Pekcec, A1
Harada, S; Matsuura, W; Tokuyama, S1
Avila-Rojas, SH; Barragán-Iglesias, P; Granados-Soto, V; Pineda-Farias, JB; Salinas-Abarca, AB1
Avdeef, A1
Baraldi, C; Cainazzo, MM; Guerzoni, S; Pellesi, L; Pini, LA1

Reviews

5 review(s) available for gabapentin and indomethacin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Pathophysiology and treatment of trigeminal autonomic cephalalgias].
    Schmerz (Berlin, Germany), 2008, Volume: 22 Suppl 1

    Topics: Administration, Oral; Amines; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cluster Headache; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Lamotrigine; Lidocaine; Male; Methysergide; Nociceptors; Oxygen Inhalation Therapy; Paroxysmal Hemicrania; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; SUNCT Syndrome; Topiramate; Triazines; Trigeminal Autonomic Cephalalgias; Trigeminal Nerve; Vasoconstrictor Agents; Vasodilator Agents; Verapamil

2008
Focus on therapy of primary stabbing headache.
    The journal of headache and pain, 2010, Volume: 11, Issue:2

    Topics: Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders, Primary; Humans; Indomethacin; Melatonin; Ophthalmic Nerve; Treatment Outcome

2010
Focus on therapy: hemicrania continua and new daily persistent headache.
    The journal of headache and pain, 2010, Volume: 11, Issue:3

    Topics: Amines; Analgesics; Celecoxib; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Headache; Headache Disorders; Humans; Indomethacin; Pyrazoles; Sulfonamides; Topiramate; Treatment Outcome

2010
Therapeutical approaches to paroxysmal hemicrania, hemicrania continua and short lasting unilateral neuralgiform headache attacks: a critical appraisal.
    The journal of headache and pain, 2017, Volume: 18, Issue:1

    Topics: Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Lamotrigine; Lidocaine; Male; Neuralgia; Paroxysmal Hemicrania; Reproducibility of Results; SUNCT Syndrome; Surveys and Questionnaires; Topiramate; Triazines; Trigeminal Autonomic Cephalalgias

2017

Trials

1 trial(s) available for gabapentin and indomethacin

ArticleYear
Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing.
    Cephalalgia : an international journal of headache, 2007, Volume: 27, Issue:7

    Topics: Amines; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Autonomic Nervous System Diseases; Cohort Studies; Conjunctiva; Cyclohexanecarboxylic Acids; Fructose; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypothalamus, Posterior; Indomethacin; Lamotrigine; Lidocaine; Magnetic Resonance Imaging; Oxygen; Pain Measurement; Phenotype; Prospective Studies; SUNCT Syndrome; Tears; Topiramate; Triazines

2007

Other Studies

29 other study(ies) available for gabapentin and indomethacin

ArticleYear
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
    Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2

    Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery of novel tetrahydro-pyrazolo [4,3-c] pyridines for the treatment of neuropathic pain: synthesis and neuropharmacology.
    European journal of medicinal chemistry, 2013, Volume: 66

    Topics: Animals; Chemistry Techniques, Synthetic; Drug Discovery; Female; Hyperalgesia; Male; Mice; Neuralgia; Neuropharmacology; Oxidative Stress; Pyrazoles; Receptors, Cannabinoid; Tumor Necrosis Factor-alpha

2013
Strictly unilateral headache reminiscent of hemicrania continua resistant to indomethacin but responsive to gabapentin.
    Cephalalgia : an international journal of headache, 2002, Volume: 22, Issue:5

    Topics: Acetates; Adult; Amines; Anti-Inflammatory Agents, Non-Steroidal; Blepharoptosis; Cyclohexanecarboxylic Acids; Diagnostic Imaging; Drug Resistance; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Male; Migraine Disorders; Neurologic Examination; Vomiting

2002
Pharmacological characterisation of a rat model of incisional pain.
    British journal of pharmacology, 2004, Volume: 141, Issue:1

    Topics: Amines; Analgesics; Animals; Behavior, Animal; Celecoxib; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Evaluation, Preclinical; Etoricoxib; Foot; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Indomethacin; Male; Morphine; Muscle, Skeletal; Naproxen; Nociceptors; Pain Threshold; Pain, Postoperative; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sulfonamides; Sulfones; Time Factors; Weight-Bearing

2004
Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy.
    Neuropharmacology, 2005, Volume: 48, Issue:5

    Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Ataxia; Behavior, Animal; Benzoxazines; Binding, Competitive; Catalepsy; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Cyclohexanecarboxylic Acids; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunosuppressive Agents; Indoles; Indomethacin; Inflammation; Male; Mice; Mice, Knockout; Morpholines; Naphthalenes; Pain; Pain Measurement; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Cannabinoid, CB2; Time Factors

2005
Nummular headache: first Italian case and therapeutic proposal.
    Cephalalgia : an international journal of headache, 2006, Volume: 26, Issue:3

    Topics: Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Indomethacin; Italy; Middle Aged; Post-Traumatic Headache

2006
Primary and secondary red ear syndrome: implications for treatment.
    Cephalalgia : an international journal of headache, 2007, Volume: 27, Issue:2

    Topics: Aged; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Ear Diseases; Erythema; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ibuprofen; Indomethacin; Middle Aged; Temporomandibular Joint Disorders; Trigeminal Autonomic Cephalalgias

2007
Is gabapentin an effective treatment choice for hemicrania continua?
    The journal of headache and pain, 2009, Volume: 10, Issue:4

    Topics: Adult; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Pathways; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Male; Middle Aged; Migraine Disorders; Retrospective Studies; Treatment Outcome; Trigeminal Nerve

2009
Abnormal gait, due to inflammation but not nerve injury, reflects enhanced nociception in preclinical pain models.
    Brain research, 2009, Oct-27, Volume: 1295

    Topics: Amines; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Axotomy; Carrageenan; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Edema; Freund's Adjuvant; Gabapentin; Gait; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Indomethacin; Inflammation; Male; Morphine; Neuralgia; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Thiophenes

2009
Chemical composition and evaluation of the anti-hypernociceptive effect of the essential oil extracted from the leaves of Ugni myricoides on inflammatory and neuropathic models of pain in mice.
    Planta medica, 2010, Volume: 76, Issue:13

    Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Bicyclic Monoterpenes; Carrageenan; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Indomethacin; Inflammation; Mice; Monoterpenes; Myrtaceae; Neuralgia; Oils, Volatile; Phytotherapy; Plant Extracts; Plant Leaves; Sciatic Neuropathy

2010
Pharmacological characterization of lysophosphatidic acid-induced pain with clinically relevant neuropathic pain drugs.
    European journal of pain (London, England), 2012, Volume: 16, Issue:7

    Topics: Amines; Analgesics; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Indomethacin; Lysophospholipids; Male; Mice; Morphine; Motor Activity; Neuralgia; Neurons; Pregabalin; Spinal Cord

2012
The role of keratinocyte-derived chemokine (KC) on hyperalgesia caused by peripheral nerve injury in mice.
    Neuropharmacology, 2014, Volume: 79

    Topics: Amines; Analgesics; Animals; Antibodies; Chemokines; Cyclohexanecarboxylic Acids; Cyclooxygenase Inhibitors; Cytokines; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Immunologic Factors; Indomethacin; Male; Mice; Neuralgia; Peripheral Nerve Injuries; Phenylurea Compounds; Receptors, Interleukin-8B; Sciatic Nerve; Spinal Cord; Touch; Vinblastine

2014
Pharmacological characterization of intraplantar Complete Freund's Adjuvant-induced burrowing deficits.
    Behavioural brain research, 2016, Mar-15, Volume: 301

    Topics: Amines; Analgesics; Animals; Antibodies; Behavior, Animal; Celecoxib; Cyclohexanecarboxylic Acids; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Ibuprofen; Indomethacin; Inflammation; Male; Morphine; Motor Activity; Nerve Growth Factor; Pain; Rats, Wistar; Tramadol

2016
Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:5

    Topics: Amines; Analgesics; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain Ischemia; Carbamazepine; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Cyclopropanes; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Imipramine; Indomethacin; Male; Mexiletine; Mice; Milnacipran; Morphine; Neuralgia; Paroxetine; Selective Serotonin Reuptake Inhibitors

2016
Formalin injection produces long-lasting hypersensitivity with characteristics of neuropathic pain.
    European journal of pharmacology, 2017, Feb-15, Volume: 797

    Topics: Activating Transcription Factor 3; Amines; Animals; Cyclohexanecarboxylic Acids; Female; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Expression Regulation; Indomethacin; Injections; Ligation; Morphine; Neuralgia; Rats; Time Factors

2017
Cocrystal solubility product analysis - Dual concentration-pH mass action model not dependent on explicit solubility equations.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Dec-15, Volume: 110

    Topics: Amines; Carbamazepine; Chemistry, Pharmaceutical; Crystallization; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Indomethacin; Models, Molecular; Molecular Conformation; Nevirapine; Osmolar Concentration; Solubility; Thermodynamics

2017