gabapentin has been researched along with gamma-aminobutyric acid in 3175 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (0.25) | 18.7374 |
| 1990's | 460 (14.49) | 18.2507 |
| 2000's | 1408 (44.35) | 29.6817 |
| 2010's | 1267 (39.91) | 24.3611 |
| 2020's | 32 (1.01) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Johnston, GA | 1 |
| Ben-Menachem, E; Hedner, T; Persson, LI | 1 |
| Chmelir, T; Ojemann, LM; Ricker, BA; Temkin, NR; Wallace, J; Wilensky, AJ | 1 |
| Chaturvedi, PR; Lodhi, SA; Nesbitt, RU; Silbering, SB; Zour, E | 1 |
| Bleavins, MR; Bobrowski, WF; Dominick, MA; Gough, AW; Robertson, DG; Sigler, RE | 1 |
| Foot, M; Wallace, J | 1 |
| Chadwick, D | 3 |
| Fromm, GH; Kondo, T; Schmidt, B | 1 |
| Hönack, D; Löscher, W; Taylor, CP | 1 |
| Graves, NM; Leppik, IE | 2 |
| Maurer, HH; Rump, AF | 1 |
| Eadie, MJ; Herkes, GK; Hooper, WD; Kavanagh, MC | 1 |
| Dickinson, RG; Hooper, WD; Kavanagh, MC | 1 |
| Porter, RJ | 1 |
| Clarenbach, P; Krätzschmar, S; Rao, ML; Vahlensieck, M | 1 |
| Blumhardt, L; Chadwick, D; Crawford, P; Ghadiali, E; Lane, R | 1 |
| Grünberger, J; Linzmayer, L; Saletu, B | 1 |
| Kölle, EU; Vollmer, KO; von Hodenberg, A | 1 |
| Hengy, H; Kölle, EU | 1 |
| Göthert, M; Reimann, W; Schlicker, E | 1 |
| Reimann, W | 1 |
| Despland, PA | 2 |
| Gil, KB; Kang, H; Moshé, SL; Shinnar, S; Wolf, SM | 1 |
| Kelly, KM; Macdonald, RL; Rock, DM | 1 |
| Kelly, KM; Macdonald, RL | 3 |
| Taylor, CP | 5 |
| Garcia, LL; Oles, K; Shihabi, ZK | 1 |
| Bockbrader, HN; Chang, T; DeHart, PD; Hanson, BJ; McNally, WP; Radulovic, LL; Türck, D; Vollmer, KO; von Hodenberg, A | 1 |
| Mellick, GA; Mellick, LB; Mellicy, LB | 1 |
| Kilpatrick, C | 1 |
| Kupecz, D | 1 |
| Cooke, L; Short, C | 1 |
| Gidal, BE; Kempf, T; Lensmeyer, GL; Wiebe, DA | 1 |
| Ryback, L; Ryback, R | 1 |
| Bockbrader, HN; Eldon, MA; Halstenson, CE; Keane, WF; Sedman, AJ; Türck, D; Underwood, BA; Wong, MO | 1 |
| Goa, KL; Sorkin, EM | 1 |
| Campbell, G; Lunney, E; Oxender, DL; Su, TZ | 1 |
| Murdoch, LA | 1 |
| de la Iglesia, FA; Gough, AW; Sigler, RE | 2 |
| Pimentel, J; Pinto, F | 1 |
| Tatum, WO; Zachariah, SB | 1 |
| Betts, T | 1 |
| Bloom, DS; O'Neill, BA; Trimble, MR | 1 |
| Brodie, MJ; Leach, JP | 1 |
| Honmou, O; Kocsis, JD; Richerson, GB | 1 |
| Devinsky, O; Luciano, D; Vazquez, B | 1 |
| Mellick, GA; Mellick, LB | 4 |
| Andrews, CO; Fischer, JH | 1 |
| Beran, RG | 1 |
| Anderson, JA; Petrere, JA | 1 |
| de la Iglesia, FA; Fowler, ML; Lalwani, ND; Reddy, JK; Sigler, RE | 1 |
| Upton, N | 1 |
| Campbell, M; Krauss, GL; Simmons-O'Brien, E | 1 |
| Tyndel, F | 1 |
| Patsalos, PN; Sander, JW | 1 |
| Kälviäinen, R; Riekkinen, PJ; Sivenius, J; Ylinen, A | 1 |
| Buchanan, N | 1 |
| Laxer, KD | 1 |
| Patsalos, PN | 2 |
| McLean, MJ | 3 |
| Ramsay, RE | 2 |
| Leiderman, DB | 1 |
| Fromm, GH | 1 |
| Honmou, O; Kocsis, JD | 1 |
| Blum, RA; Bockbrader, H; Busch, JA; Comstock, TJ; Keller, E; Reece, PA; Reetze, P; Schultz, RW; Sica, DA; Tuerck, D | 1 |
| Dostrow, VG; Noble, SL; Parks, BR | 1 |
| Byers, VL | 1 |
| Schielke, GP; Taylor, CP; Vartanian, MG; Welty, DF | 1 |
| Leppik, IE | 1 |
| McLean, MJ; Wamil, AW | 1 |
| Harden, CL | 2 |
| Barr, AN; Fischer, JH; Fischer, PA; Rogers, SL; Trudeau, VL | 1 |
| Manack, L; Skolnick, AA | 1 |
| Ramsay, RE; Slater, JD | 1 |
| Okamoto, Y; Ota, K | 1 |
| Brown, JP; Gee, NS; Hill, DR; Thurlow, RJ; Woodruff, GN | 1 |
| Bigge, C; Hill, DR; Suman-Chauhan, N; Taylor, CP; Vartanian, MG; Yuen, PW | 1 |
| Hill, DR; Suman-Chauhan, N; Webdale, L; Woodruff, GN | 1 |
| Hill, DR; Suman-Chauhan, N; Woodruff, GN | 1 |
| Feuerstein, TJ; Götz, E; Lais, A; Meyer, DK | 1 |
| Bockbrader, HN; Kugler, AR; Stewart, BH; Thompson, PR | 1 |
| Bialer, M | 2 |
| Aguilera, L; Fauré, E; Galdames, D | 1 |
| Lee, EK | 1 |
| Ben-Menachem, E; Hamberger, A; Hedner, T; Persson, LI; Söderfelt, B | 1 |
| Honmou, O; Kocsis, JD; Oyelese, AA | 1 |
| Kochen, S | 1 |
| Goldlust, A; Oxender, DL; Su, TZ; Taylor, CP; Welty, DF | 1 |
| Behar, KL; Lamoureux, D; Mattson, RH; Petroff, OA; Rothman, DL | 1 |
| Cory, PR; Gidal, Be | 1 |
| Rothstein, JD; Schielke, GP; Welty, DF | 1 |
| Vassella, F | 1 |
| Krämer, G | 1 |
| Shokry, A | 1 |
| Despland, PA; Krämer, G; Vassella, F; Wieser, HG | 1 |
| Cesena, M; Helmers, SL; Lee, DO; Mikati, MA; Riviello, JJ; Steingard, RJ | 1 |
| Cochran, JW; Williams, LB | 1 |
| Lo, W; Nahata, MC; Tallian, KB; Tsao, CY | 2 |
| Buetefisch, CM; Gutierrez, A; Gutmann, L | 1 |
| Vossler, DG | 1 |
| Brown, JP; Dissanayake, VU; Gee, NS; Offord, J; Thurlow, R; Woodruff, GN | 1 |
| Reynolds, NC | 1 |
| French, JA | 1 |
| Perucca, E | 2 |
| Zapp, JJ | 2 |
| Pellock, JM | 4 |
| Anderson, J; Helmers, S; Holmes, G; Khurana, DS; Mikati, MA; Riviello, J | 1 |
| Legido, A | 1 |
| Kanthasamy, AG; Truong, DD; Vu, TQ; Yun, RJ | 1 |
| Beydoun, A; Sackellares, JC; Uthman, BM | 1 |
| Gaily, E; Iivanainen, M | 1 |
| Loiseau, P | 1 |
| Wang, Y; Welty, DF | 1 |
| Fernández, MC; Petersen, LR; Walkotte, SM; Walter, FG | 1 |
| Davies, JA | 1 |
| Kestenbaum, A; Rosner, H; Rubin, L | 1 |
| Perry, JR; Sawka, C | 1 |
| Romano, JG | 1 |
| Hill, DR; Thurlow, RJ; Woodruff, GN | 2 |
| Dimond, KR; Lamoreaux, L; Pande, AC; Pierce, MW | 1 |
| Naritoku, DK; Patel, J | 1 |
| Rordorf, G; Segal, AZ | 1 |
| Binnie, CD; Elwes, RD | 1 |
| Cockerell, OC; Hughes, D | 1 |
| McDonnell, GV; Morrow, JI | 1 |
| Lönnecker, S; Paulus, W; Steinhoff, BJ; Ziemann, U | 1 |
| Bourgeois, BF | 4 |
| Brodie, MJ; Forrest, G; Leach, JP; Sills, GJ | 1 |
| Haider, A; Haider, S; Tuchek, JM | 1 |
| Krahn, LE; Reeves, AL; Sharbrough, FW; So, EL | 1 |
| Bhaumik, S; Hauck, A | 1 |
| Gidal, BE; Haley, K; Maly, MM; Nemire, RE | 1 |
| Hussein, G; Montouris, G; Troupin, AS | 1 |
| Lee, BI | 1 |
| Ferris, P; Field, MJ; Hunter, JC; Oles, RJ; Singh, L; Williams, RG; Woodruff, GN | 1 |
| Morton, LD; Pellock, JM | 1 |
| Poklis, A; Saady, JJ; Wolf, CE | 1 |
| Cook, LL; Persinger, MA | 1 |
| Duthie, T; Jackson, D | 1 |
| Williams, DC | 1 |
| Chadwick, DW; Kadir, ZA; Marson, AG | 1 |
| Budde, J; Gidal, BE; Jones, JC; Lensmeyer, GL; Maly, MM; Pitterle, ME | 1 |
| Meldrum, BS | 1 |
| Gram, L | 1 |
| Chadwick, DW; Kadir, Z; Marson, T | 1 |
| Mattson, RH | 1 |
| Brady, LA; Do, SM; Fernandez, MC; Kloster, JC; Prosnitz, EH; Ruffenach, SJ; Salmon, JV; Villarin, A; Walter, FG | 1 |
| Bruni, J | 3 |
| Alexander, J; Chadwick, D; Garofalo, E; Leiderman, DB; Sauermann, W | 1 |
| Armon, C; Barohn, RJ; Bromberg, MB; Bryan, WW; Gelinas, DF; Mendoza, MC; Miller, RG; Moore, D; Neville, HE; Parry, GJ; Petajan, JH; Ravits, JM; Ringel, SP; Ross, MA; Young, LA | 1 |
| Andrus, PK; Cutting, FB; Doble, A; Gurney, ME; Hall, ED; Taylor, CP; Zhai, P | 1 |
| Herranz, JL | 2 |
| Grippo, J | 1 |
| Appleton, RE | 1 |
| Bloms-Funke, P; Löscher, W | 1 |
| Gordon, SM; Regan, WM | 1 |
| Keck, PE; McElroy, SL; Stanton, SP | 1 |
| Schaffer, CB; Schaffer, LC | 2 |
| Fleisher, D; Kim, J; Stevenson, CM | 1 |
| Nissani, M; Sanchez, EA | 1 |
| Morris, HH | 2 |
| Brodie, MJ; Wilson, EA | 1 |
| Graves, DE; Mueller, M; Olson, WH; Priebe, MM; Sherwood, AM | 1 |
| Johannessen, SI | 1 |
| Shorvon, S; Stefan, H | 1 |
| Bannister, SM; Morton, LD; Pellock, JM | 1 |
| Adler, CH | 1 |
| Kosek, P; McGraw, T | 1 |
| Dickenson, AH; Singh, L; Stanfa, LC; Williams, RG | 1 |
| Hosford, DA; Wang, Y | 1 |
| Anhut, H; Ebersole, J; Garofalo, E; LaMoreaux, L; Myers, S; Trudeau, V | 1 |
| Brodie, MJ; Girvan, J; Leach, JP; Paul, A | 1 |
| Davis, AM; Elliott, KJ; Inturrisi, CE; Shimoyama, M; Shimoyama, N | 1 |
| Brown, JP; Dissanayake, VU; Gee, NS; Woodruff, GN | 1 |
| Brodsky, L; Munasifi, F; Ryback, RS | 1 |
| Fontana, DJ; Gogas, KR; Hedley, LR; Hunter, JC; Jacobson, LO; Kassotakis, L; Thompson, J | 1 |
| Arbizu, T; Padró, L; Rovira, R | 1 |
| Filadora, V; Lema, M; Miner, M; Sist, T | 1 |
| Bergen, D; Blesi, K; Gapany, S; Gil-Nagel, A; Villanueva, N | 1 |
| Bhaumik, S; Branford, D; Duggirala, C; Ismail, IA | 1 |
| Chapman, DP; Giles, WH | 1 |
| Gruenthal, M; Mueller, ME; Olson, WH; Olson, WL | 2 |
| Averbuch-Heller, L; Büttner, U; Fuhry, L; Ganser, GL; Heide, W; Leigh, RJ; Rottach, KG; Tusa, RJ | 1 |
| Childers, MK; Holland, D | 1 |
| Daras, M; Koppel, BS; Samkoff, LM; Tuchman, AJ | 1 |
| Chudnow, RS; Dewey, RB; Lawson, CR | 1 |
| Brodie, MJ; Butler, E; Forrest, G; Leach, JP; Sills, GJ; Thompson, GG | 1 |
| Stringer, JL; Xiong, ZQ | 1 |
| Vossler, DG; Wyler, AR | 1 |
| Keck, PE; Kmetz, GF; McElroy, SL; Soutullo, CA | 1 |
| Barrientos, N; Chaná, P; de Marinis, A | 1 |
| Dalby, NO; Nielsen, EB | 1 |
| DeCerce, J; DeToledo, JC; Ramsay, RE; Toledo, C | 1 |
| Bockbrader, HN; Fleisher, D; Radulovic, LL; Stevenson, CM | 1 |
| Field, MJ; Hughes, J; Lewis, AS; McCleary, S; Oles, RJ; Singh, L | 1 |
| Connelly, JF; Wetzel, CH | 1 |
| de Rosayro, AM; Harrell, C; Ristic, H; Rosenberg, JM; Werner, RA | 1 |
| Bergey, GK; Blume, WT; Crockatt, JG; Garofalo, E; LaMoreaux, L; Leiderman, DB; Morrell, MJ; Morris, HH; Penovich, PE; Pierce, M; Rosenfeld, W | 1 |
| Abou-Khalil, B; Beydoun, A; Cantrell, D; Fischer, J; Garofalo, E; Greiner, M; Harden, C; Hayes, A; Labar, DR; Pierce, M; Ramsay, RE; Sackellares, JC; Uthman, BM | 1 |
| Barron, TF; Hunt, SL | 1 |
| Elliott, KJ; Inturrisi, CE; Shimoyama, M; Shimoyama, N | 1 |
| Carson, WH; Finkenbine, R; King, L; Markowitz, JS; Myrick, H | 1 |
| Field, MJ; Holloman, EF; Hughes, J; McCleary, S; Singh, L | 1 |
| Holmes, GL | 1 |
| Autret, E; Billard, C; Jonville-Bera, AP; Picard, C | 1 |
| Joffe, RT; MacDonald, C; Patelis-Siotis, I; Robb, JC; Young, LT | 1 |
| Gruenthal, M; Mueller, M; Olson, WH; Olson, WL; Priebe, MM; Sherwood, AM | 1 |
| Chudnow, RS; Mimbela, RA; Owen, DB; Roach, ES | 1 |
| Khatri, A; Pearlstein, L | 1 |
| Houtchens, MK; Richert, JR; Rose, JW; Sami, A | 1 |
| Pierce, MW; Shokry, A | 1 |
| Franm, L; Lucier, E | 1 |
| Del Bianco, PL; Nicolodi, M; Sicuteri, F | 1 |
| Little, HJ; Robinson, E; Watson, WP | 1 |
| Gillin, S; Sorkin, LS | 1 |
| Freeman, MP; Stoll, AL | 1 |
| Chaplan, SR; Partridge, BJ; Sakamoto, E; Yaksh, TL | 1 |
| Briggs, AR; Brown, JP; Dissanayake, VU; Gee, NS; Milic, MR | 1 |
| Jun, JH; Yaksh, TL | 1 |
| Newshan, G | 1 |
| Stopforth, J | 1 |
| Curry, WJ; Kulling, DL | 1 |
| Brodie, MJ; Forrest, G; Sills, GJ; Wilson, EA | 1 |
| Bailey, CP; Little, HJ; Molleman, A | 1 |
| Krämer, G; Wad, N | 1 |
| Bazil, CW; Pedley, TA | 1 |
| Gould, HJ | 1 |
| Bittermann, HJ; Herrendorf, G; Kurth, C; Steinhoff, BJ | 1 |
| Corá-Locatelli, G; Greenberg, BD; Martin, JD; Murphy, DL | 1 |
| Johannessen, SI; Nakken, KO; Rytter, E | 2 |
| Arzimanoglou, A; Baulac, M; Cavalcanti, D; Portal, JJ; Semah, F | 1 |
| Boden, P; Brown, JP; Dooley, DJ; Gee, NS; Kocsis, JD; Singh, L; Su, TZ; Taylor, CP; Welty, DF | 1 |
| Petroff, OA; Rothman, DL | 1 |
| McCaffery, M | 1 |
| Boothe, DM | 1 |
| Beauclair, L; Bélanger, MC; Chouinard, G | 1 |
| Cook, DE; Gidal, BE; Kowalski, JW; Maly, MM; Pitterle, ME; Rutecki, PA | 1 |
| Eldon, MA; Randinitis, EJ; Sedman, AJ; Underwood, BA | 1 |
| Carrazana, EJ; Schachter, SC | 1 |
| Abou-Khalil, B; Beydoun, A; Fakhoury, T; Nasreddine, W | 1 |
| Beck, H; Elger, CE; Schramm, J; Schumacher, TB; Steinhäuser, C | 1 |
| Chadwick, DW; Hutton, JL; Kadir, ZA; Marson, AG | 3 |
| Haugvicová, R; Mares, P | 1 |
| Birnbaum, AK; Caruso, KJ; Cloyd, JC; Jones Saete, C; Kriel, RL; Ricker, BJ | 1 |
| Baraldo, M; Benetello, P; Fortunato, M; Furlanut, M; Pea, F; Testa, G; Tognon, A | 1 |
| Chamarette, HL; Chapman, V; Dickenson, AH; Rygh, LJ; Suzuki, R | 1 |
| Miller, RG | 2 |
| Luer, MS; Winkler, SR | 1 |
| Bauer, J; Elger, CE; Scherrmann, J; Widman, G | 1 |
| Ancill, RJ; Holliday, SG; Sheldon, LJ | 1 |
| Cho, EH; Cho, SW; Choi, SY | 1 |
| Bryans, JS; Davies, N; Dissanayake, VU; Gee, NS; Horwell, DC; Kneen, CO; Morrell, AI; O'Neill, JA; O'Toole, JC; Oles, RJ; Perkins, GM; Ratcliffe, GS; Singh, L; Suman-Chauhan, N | 1 |
| Privitera, M; Shukla, R; Welty, TE | 1 |
| Anderson, GD | 1 |
| Busenbark, K; Hubble, JP; Koller, WC; Lyons, K; Pahwa, A; Pahwa, R; Rienerth, JD | 1 |
| Knoll, J; Stegman, K; Suppes, T | 1 |
| Dooley, DJ; Pugsley, TA; Whetzel, SZ | 1 |
| García-Albea, E | 1 |
| Casuto, LS; Keck, PE; Soutullo, CA | 1 |
| Köhling, R; Lücke, A; Mayer, T; Musshoff, U; Osterfeld, M; Schütte, W; Speckmann, EJ; Wolf, P | 1 |
| Matthews, J; Pollack, MH; Scott, EL | 1 |
| De Sarro, A; De Sarro, G; Gallelli, L; Gareri, P; Spagnolo, C | 1 |
| Evans, DL; Murphy, TK; Tueth, MJ | 1 |
| Keck, PE; McElroy, SL; Strakowski, SM | 1 |
| Nicolodi, M; Sicuteri, F | 1 |
| Bernardi, G; Spadoni, F; Stefani, A | 1 |
| Aschner, M; Berkich, D; Drown, P; Hutson, SM; LaNoue, KF; Xu, B | 1 |
| Bhat, S; Blinder, BJ; Sanathara, VA | 1 |
| Büttner, U; Fuhry, L; Noachtar, S; von Maydell, B | 1 |
| Carlton, SM; Zhou, S | 1 |
| Capello, E; Inglese, M; Lunardi, GL; Mancardi, GL; Messmer Uccelli, M; Solaro, C; Uccelli, A | 1 |
| Khan, OA | 1 |
| Patsalos, PN; Ratnaraj, N | 1 |
| Bockbrader, HN; DeCerce, J; Gidal, BE; Gonzalez, J; Kruger, S; Pitterle, ME; Ramsay, RE; Rutecki, P | 1 |
| Merren, MD | 1 |
| Desai, SP; Ghaemi, SN; Goodwin, FK; Katzow, JJ | 1 |
| Gatautis, V; Van Lente, F | 1 |
| Bergler, W; Hein, G; Petroianu, A; Petroianu, G; Rüfer, R | 1 |
| Basavaraju, N; Goldenberg, G; Kahaner, K; Rangu, S | 1 |
| D'Andreamatteo, G; Onofrj, M; Paci, C; Thomas, A | 1 |
| Hildebrandt, J; Paulus, W; Tergau, F; Wischer, S; Ziemann, U | 1 |
| Adler, CH; Caviness, JN; Evidente, VG; Gwinn, KA | 1 |
| Corá-Locatelli, G; Greenberg, BD; Martin, J; Murphy, DL | 1 |
| Podell, M | 1 |
| Hagan, RM; Xie, X | 1 |
| Kelly, KM | 1 |
| Ferrier, IN | 1 |
| Bungert, M; Dittert, S; Erfurth, A; Grunze, H | 1 |
| Sánchez-Valiente, S | 1 |
| Emmers, E; Mortimore, C; Trimble, M | 1 |
| Kerr, MP; Thijs, RD | 1 |
| Brambilla, A; Erli, LC; Grandi, R; Mirabile, D; Zadra, M | 1 |
| Selai, CE; Trimble, MR | 1 |
| Hagan, RM; Higgins, GA; Kirkby, D; Southam, E | 1 |
| Brady, KT; Malcolm, R; Myrick, H | 1 |
| Jones, DL; Sorkin, LS | 1 |
| Attal, N; Bouhassira, D; Brasseur, L; Chauvin, M; Parker, F | 1 |
| Alexander, J; Anhut, H; Chadwick, DW; Garofalo, EA; Greiner, MJ; Murray, GH; Pierce, MW | 1 |
| Cano, A; Gonzalez-Sicilia, L; Hernandez, J; Serrano, M | 1 |
| Kezar, L; Liu, HG; Mountz, JM; Ness, TJ; Richards, SJ; San Pedro, EC | 1 |
| Abdi, S; Chung, JM; Lee, DH | 1 |
| Backonja, M; Beydoun, A; Edwards, KR; Fonseca, V; Garofalo, E; Hes, M; LaMoreaux, L; Schwartz, SL | 1 |
| Bernstein, P; Harden, N; Magnus-Miller, L; Rowbotham, M; Stacey, B | 1 |
| Dotson, RM; Low, PA | 1 |
| Balzarini, C; Brigatti, M; Comazzi, F; Mazzini, L; Mora, G; Pastore, E; Pirali, I | 1 |
| Corá-Locatelli, G; Dunn, RT; Frye, MA; Grothe, D; Ketter, TA; Kimbrell, TA; Piscitelli, S; Post, RM; Vanderham, E | 1 |
| Chuecos, S; Hernández, L; Pérez, J; Rada, P; Teneud, L; Tucci, S | 1 |
| de Andrade, MP; de Oliveira, JO; Fortini, I | 1 |
| McGraw, T; Stacey, BR | 1 |
| Cardinali, P; Parisi, L; Pierelli, F; Rossi, P; Serrao, M; Tramutoli, R | 1 |
| Feely, M | 1 |
| Wilner, AN | 1 |
| Hammond, DL; Kaneko, M; Mestre, C | 1 |
| Elger, CE; Mayer, T; Schütte, W; Wolf, P | 1 |
| Faught, E; Gilliam, F; Hetherington, H; Ho, S; Kuzniecky, R; Martin, R; Pan, J; Sinclair, K | 1 |
| Constantino, C; Corá-Locatelli, G; Frye, MA; Grothe, D; Ketter, TA; Kimbrell, TA; Luckenbaugh, D | 1 |
| Duncan, JS; Langan, Y; Sander, JW | 1 |
| Chen, SR; Eisenach, JC; Pan, HL | 1 |
| Choueri, R; Helmers, S; Holmes, G; Khurana, DS; Mikati, MA; Riviello, J | 1 |
| DeToledo, JC; Lowe, MR; Minagar, A; Ramsay, RE | 1 |
| Gorson, KC; Herman, R; Rand, WM; Ropper, AH; Schott, C | 1 |
| Seidl, JJ; Slawson, JG | 1 |
| Lorenzo, N; Stringer, JL | 1 |
| Leigh, RJ; Ramat, S | 1 |
| Berger, J; Vadivelu, N | 1 |
| Bernardi, G; Calabresi, P; Centonze, D; Marfia, GA; Pisani, A | 1 |
| Bryans, JS; Wustrow, DJ | 1 |
| Barbanoj, M; Gironell, A; Hernández, G; Kulisevsky, J; López-Villegas, D; Pascual-Sedano, B | 1 |
| Calcutt, NA; Ceseña, RM | 1 |
| Field, MJ; Hughes, J; McCleary, S; Singh, L | 1 |
| Nahata, MC | 1 |
| Christodoulou, GN; Hatzimanolis, J; Lykouras, L; Oulis, P | 1 |
| MacQueen, GM; Mazurek, MF; Rosebush, PI | 1 |
| Esparcia Navarro, M; García Callejo, FJ; Marco Algarra, J; Martínez Beneyto, MP; Morant Ventura, A; Talamantes Escribá, F | 1 |
| Abel, RB; Bockbrader, HN; Boyd, RA; Sedman, AJ; Türck, D | 1 |
| Cabras, PL; Carta, MG; Hardoy, MC; Hardoy, MJ | 2 |
| Löscher, W; Richter, A | 1 |
| Bockbrader, HN; Fleisher, D; Jezyk, N; Li, C; Stewart, BH; Wu, X | 1 |
| Maidment, NT; Ondarza-Rovira, R; Rocha, L | 1 |
| Letterman, L; Markowitz, JS | 1 |
| Boyce, S; Hill, RG; Mason, G; O'Donnell, R; Rigby, M; Rupniak, NM; Sirinathsinghji, D; Webb, JK; Wyatt, A | 1 |
| Carvill, S; Cassidy, G; Clarke, D | 1 |
| Hamer, HM; Morris, HH | 1 |
| Labbate, LA; Rubey, RN | 1 |
| Lovell, RW | 1 |
| Jiang, Q; Li, S | 1 |
| DeGrauw, T; Glauser, TA; Miles, MV; Tang, PH | 1 |
| Mancardi, GL; Solaro, C; Uccelli, MM | 1 |
| McManaman, J; Tam, DA | 1 |
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| Atkinson, LZ; Awad, A; Cipriani, A; Forrest, A; Geddes, JR; Harrison, PJ; Houghton, KT; Stockton, S | 1 |
| Amin, S; Anthony, C; Caparó, M; Eloy, JD; Reilly, MC; Shulman, S | 1 |
| Bell, P; Glinn, MA; Harvey, A; Lickteig, AJ; Rappold, B; Recer, S; Salske, M; Stensland, J; Weber, L | 1 |
| Avdeef, A | 1 |
| Li, C; Peng, C; Qu, J; Wu, D | 1 |
| Khezri, MB; Nasseh, N; Soltanian, G | 1 |
| Friciu, M; Leclair, G; Roullin, VG | 1 |
| De Decker, S; De Risio, L; Dennis, R; Gielen, I; Goethals, K; Mauler, DA; Van der Vekens, E; Van Ham, L; Volk, HA | 1 |
| Schwarcz, R; Snodgrass, HR; Yaksh, TL | 1 |
| Mulier, J | 1 |
| Azurara, L; Correia, CR; Palaré, MJ; Soares, AT | 1 |
| Fairman, KA; Peckham, AM; Sclar, DA | 5 |
| Cao, Y; Liao, Z; Lu, XM; Mountney, A; Shear, DA; Tortella, FC | 1 |
| Anaya, CJ; Enriquez, C; Jolivalt, CG; Marquez, A; Nicodemus, JM | 1 |
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| Huh, J; Kim, HJ; Kim, KM; Lee, JM; Lee, SK; Park, EY | 1 |
| Canner, JK; Dickersin, K; Fusco, N; Hong, H; Li, T; Mayo-Wilson, E | 1 |
| Katz, P; Liedgens, H; Pegoraro, V | 1 |
| Lyon, J | 1 |
| Jermendy, G; Kempler, P; Keresztes, K; Körei, A; Lengyel, C; Martos, T; Nyiraty, S; Putz, Z; Stirban, A; Várkonyi, T | 1 |
| Gannon, R; O'Sullivan, DM; Reagan, KML; Steinberg, AC | 1 |
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| Amabili, P; Jadhav, SV; Sewald, N; Stammler, HG | 1 |
| Corona-Ramos, JN; Déciga-Campos, M; García-López, P; Jaramillo-Morales, OA; López-Muñoz, FJ; Martínez-Racine, I; Medina, LA; Romero-Piña, M | 1 |
| Bell, RF; Derry, S; Moore, RA; Phillips, T; Rice, AS; Tölle, TR; Wiffen, PJ | 1 |
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| Antoniou, T; Gomes, T; Ho, JM; Juurlink, DN; Luo, J; Macdonald, EM; Mamdani, MM | 1 |
| Afthinos, M; Bögli, SY; Huang, MY | 1 |
| Dahl, JB; Fabritius, ML; Geisler, A; Mathiesen, O; Petersen, PL; Wetterslev, J | 1 |
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| Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J | 2 |
| Edwards, JC; Ibrahim, H; Oman, Z; Schuelke, M | 1 |
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| Chen, J; Guan, SM; Luo, WJ; Sun, W; Wang, JL; Wang, JS; Wang, XL; Wu, FF; Yang, F; Zheng, W | 1 |
| Baraldi, C; Cainazzo, MM; Guerzoni, S; Pellesi, L; Pini, LA | 1 |
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| Gabel-Jensen, C; Heegaard, AM; Juul, RV; Kreilgaard, M; Lund, TM; Papathanasiou, T | 1 |
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| Li, X; Qin, S; Sun, D; Tang, R; Wang, D; Wang, L; Yang, J; Yu, Q | 1 |
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| Lin, JP | 1 |
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| Bernard, N; Bhattacharya, S; Brown, M; Klapstein, G; Marske, C; Palacios, A; Preiss, B; Wheeler, C | 1 |
| Aboagye, DE; Alaie, D; Chulpayev, B; Ishkanian, G; Kolanuvada, B; Liu, L; Miao, J; Petrillo, RL | 1 |
| Coors, L; Hesseling, B; Langendijk, PNJ; Mathijssen, NMC; van Dasselaar, NT; van Haagen, MHM; Verburg, H | 1 |
| Baranowski, A; Bhattacharya, S; Birch, J; Cheong, Y; Cregg, R; Daniels, J; Hewitt, CA; Horne, AW; Macfarlane, GJ; Middleton, L; Szubert, W; Tracey, I; Vincent, K; Williams, ACC | 1 |
| Liang, X; Su, R; Yu, G | 1 |
| Aksu, A; Cakirgöz, MY; Demirel, I; Duran, E; Ersoy, A; Hancı, V; Özer, AB; Türkmen, UA | 1 |
| Arguelles-Uribe, GD; Carrillo-Torres, O; Corral-Urdapilleta, NP; Guzmán-Sánchez, JA; Rascón-Martínez, DM; Soto-Palma, G; Velázquez-Loeza, J | 1 |
| Abdelwahab, S; Abdelzaher, WY; Ibrahim, MA; Rofaeil, RR | 1 |
| Barragán-Iglesias, P; Delgado-Lezama, R; Granados-Soto, V; Hong, E; Loeza-Alcocer, E; Oidor-Chan, VH; Pineda-Farias, JB; Price, TJ; Salinas-Abarca, AB; Sánchez-Mendoza, A; Velazquez-Lagunas, I | 1 |
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| Abdel-Wahhab, KG; Daoud, EM; El Gendy, A; Mannaa, FA; Mourad, HH; Saber, MM | 1 |
| Burneo, J; Dev, VK; Dixon, SN; Fleet, JL; Garg, AX; Kuwornu, PJ; Montero-Odasso, M | 1 |
| Castro Alves, LJ; Kendall, MC | 1 |
| Baviera, AM; Benzi, JRL; de Moraes, NV; Stevens, JH; Yamamoto, PA | 1 |
| Bunn, TL; Christy, D; Kirschke, D; Light, T; Miller, A; Slavova, S; Thompson, G; White, JR; Winecker, R | 1 |
| Aronoff, GM; Ciric, S; Lal, R; Swearingen, D | 1 |
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| Iżycka, N; Kapoła-Czyż, J; Lorek, J; Magnowska, M; Nowak-Markwitz, E; Romała, A; Spaczyński, M | 1 |
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| Chincholkar, M | 1 |
| Akiyama, T; Andoh, T; Kuraishi, Y; Nojima, H; Ohtsuka, E; Ouchi, H; Takahata, H | 1 |
| Gottlieb, S; Throckmorton, DC; Woodcock, J | 1 |
| Fu, B; Huang, T; Liu, SJ; Wang, B; Wang, J; Weng, XC | 1 |
| Amato, L; Amin-Esmaeili, M; Gholami, J; Hoseinie, L; Rahimi-Movaghar, A; Yousefi-Nooraie, R | 1 |
| Guitart, J; Martinez-Escala, ME; Serrano, L; Zhou, XA | 1 |
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| Arevalo-Rodriguez, I; Franco, JV; Hidalgo, R; Osorio, D; Simancas-Racines, D; Xu, Y | 1 |
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| Dai, ZG; Gao, CX; Li, L; Ma, KT; Si, JQ; Wang, S; Zhang, M | 1 |
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| Baratta, JL; Dayan, AC; Pitchon, DN; Schwenk, ES; Viscusi, ER | 1 |
| Frigui, W; Jebali, C; Kahloul, M; Naija, W; Nakhli, MS | 1 |
| Alvarado-Franco, NL; Femat-Roldan, G; Garza-Alpirez, A; Gonzalez-Marques, C; Martinez-Ramirez, D; Olguín-Ramírez, LA | 1 |
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| Huang, Q; Jiang, Y; Li, J; Lin, H; Rong, Z; Wang, T; Xiong, J; Zhang, Q; Zhang, S | 1 |
| Al-Bachari, S; Hutton, JL; Marson, AG; Panebianco, M; Weston, J | 1 |
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| Chen, X; Dickinson, S; Golzarri-Arroyo, L; Görg, C; Hong, H; Li, T; Mayo-Wilson, E; Qureshi, R | 1 |
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655 review(s) available for gabapentin and gamma-aminobutyric acid
| Article | Year |
|---|---|
GABAA agonists as targets for drug development.
Topics: Acetates; Acrylates; Amines; Analgesics; Anthelmintics; Anticonvulsants; Bicuculline; Computer Simulation; Cyclohexanecarboxylic Acids; Cyclopentanes; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Isoxazoles; Molecular Conformation; Molecular Weight; Receptors, GABA-A | 1992 |
Gabapentin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drugs, Investigational; Electroencephalography; Epilepsy; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Humans | 1991 |
Antiepileptic medications in development.
Topics: Acetates; Amines; Aminocaproates; Animals; Anticonvulsants; Chemistry, Pharmaceutical; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Drugs, Investigational; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1991 |
[Current viewpoints in the treatment of epilepsies: role of new antiepileptics?].
Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Tolerance; Enzyme Inhibitors; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin | 1995 |
Mechanisms of action of currently prescribed and newly developed antiepileptic drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drugs, Investigational; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Mice; Phenylcarbamates; Propylene Glycols; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Triazines; Valproic Acid | 1994 |
Emerging perspectives on the mechanism of action of gabapentin.
Topics: Acetates; Amines; Amino Acids; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Leucine; Neurotransmitter Agents; Receptors, Neurotransmitter | 1994 |
Antiepileptic drug mechanisms of action.
Topics: Acetates; Action Potentials; Amines; Anticonvulsants; Calcium Channels; Cyclohexanecarboxylic Acids; Drug Design; Epilepsy, Generalized; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Receptors, GABA-A; Receptors, Neurotransmitter; Sodium Channels; Triazines; Valproic Acid | 1993 |
Gabapentin. A review of its pharmacological properties and clinical potential in epilepsy.
Topics: Acetates; Amines; Animals; Anticonvulsants; Biological Availability; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Tolerance; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Tissue Distribution | 1993 |
[New antiepileptic medications].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin; Zonisamide | 1995 |
Adjunctive therapy in epilepsy: a cost-effectiveness comparison of alternative treatment options.
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Decision Support Techniques; Drug Therapy, Combination; Drug Tolerance; Electroencephalography; Epilepsy; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Long-Term Care; Triazines; Vigabatrin | 1995 |
New antiepileptic drugs--an explosion of activity.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Approval; Drug Interactions; Drug Therapy, Combination; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Product Surveillance, Postmarketing; Treatment Outcome; Triazines; Vigabatrin | 1995 |
New antiepileptic drugs for children: felbamate, gabapentin, lamotrigine, and vigabatrin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsies, Partial; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; United States; United States Food and Drug Administration; Vigabatrin | 1994 |
Gabapentin: a new agent for the management of epilepsy.
Topics: Acetates; Adult; Age Factors; Amines; Anticonvulsants; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsies, Partial; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Randomized Controlled Trials as Topic | 1994 |
Mechanisms of action of new antiepileptic drugs: rational design and serendipitous findings.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1994 |
Gabapentin.
Topics: Acetates; Adult; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1994 |
Newer antiepileptic drugs. Towards an improved risk-benefit ratio.
Topics: Acetamides; Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Piracetam; Propylene Glycols; Risk Factors; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 1994 |
New anti-epileptic drugs in the 1990s.
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Cyclohexanecarboxylic Acids; Drugs, Investigational; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1994 |
Guidelines for treating epilepsy in the age of felbamate, vigabatrin, lamotrigine, and gabapentin.
Topics: Acetates; Adult; Amines; Animals; Anticonvulsants; Child; Clinical Protocols; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines | 1994 |
Phenobarbitone to gabapentin: a guide to 82 years of anti-epileptic drug pharmacokinetic interactions.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Metabolic Clearance Rate; Phenobarbital | 1994 |
Clinical pharmacokinetics of gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1994 |
Clinical efficacy and safety of gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsies, Partial; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Randomized Controlled Trials as Topic | 1994 |
Gabapentin: discussion.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drugs, Investigational; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Complex Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Neural Pathways; Treatment Outcome; Trigeminal Nuclei | 1994 |
Drug therapy for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Decision Trees; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Patient Education as Topic; Phenylcarbamates; Propylene Glycols; Triazines | 1994 |
Antiepileptic drugs in development: prospects for the near future.
Topics: Acetates; Adult; Amines; Aminocaproates; Animals; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Approval; Drug Design; Drugs, Investigational; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin; Zonisamide | 1994 |
New antiepileptic drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Triazines; Vigabatrin | 1994 |
Advances in pharmacotherapy: recent developments in the treatment of epilepsy.
Topics: Acetates; Amines; Aminocaproates; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1993 |
Antiepileptic drugs in clinical development.
Topics: Acetates; Amines; Aminocaproates; Anticonvulsants; Brain; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Structure-Activity Relationship; Synaptic Transmission; Tiagabine; Topiramate; Triazines; Vigabatrin | 1993 |
[Diagnosis and therapy of epilepsy and myoclonus].
Topics: Acetates; Amines; Cerebral Cortex; Cyclohexanecarboxylic Acids; Electrophysiology; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Myoclonus; Phenytoin | 1993 |
Advances in the pharmacotherapy of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines | 1993 |
Comparative pharmacokinetics of the newer antiepileptic drugs.
Topics: Acetamides; Acetates; Amines; Aminocaproates; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Felbamate; Flunarizine; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1993 |
[Refractory epilepsy in adults and the new antiepileptic drugs: the role of gabapentin].
Topics: Acetates; Amines; Anticonvulsants; Chile; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Resistance; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1995 |
Potential use of gabapentin and lamotrigine.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drugs, Investigational; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines | 1995 |
[Gabapentin (Neurontin): a new possibility in the add-on therapy of partial epilepsies].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic | 1996 |
Clinical efficacy of new antiepileptic drugs in refractory partial epilepsy: experience in the United States with three novel drugs.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsies, Partial; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Phenylcarbamates; Placebos; Propylene Glycols; Randomized Controlled Trials as Topic; Topiramate; Treatment Outcome; United States | 1996 |
Pharmacokinetic profile of topiramate in comparison with other new antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin | 1996 |
Utilization of new antiepileptic drugs in children.
Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1996 |
[Advances in the diagnostic and treatment of infantile epilepsy].
Topics: Acetates; Amines; Anticonvulsants; Brain; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Electroencephalography; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Magnetic Resonance Imaging; Phenylcarbamates; Propylene Glycols; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Triazines; Vigabatrin | 1996 |
Gabapentin: pharmacokinetics, efficacy, and safety.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans | 1995 |
[Current anti-epilepsy drugs].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1995 |
Mechanisms of action of antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; N-Methylaspartate; Neural Pathways; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1995 |
Antiepileptic drug mechanisms of action.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Calcium Channels; Carbamazepine; Central Nervous System; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Phenytoin; Rats; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium Channels; Triazines; Trimethadione; Valproic Acid; Vigabatrin | 1995 |
Gabapentin.
Topics: Acetates; Adult; Amines; Animals; Anticonvulsants; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregnancy; Treatment Outcome | 1995 |
Clinical pharmacokinetics of newer antiepileptic drugs. Lamotrigine, vigabatrin, gabapentin and oxcarbazepine.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Tissue Distribution; Triazines; Vigabatrin | 1996 |
A cost minimization study comparing vigabatrin, lamotrigine and gabapentin for the treatment of intractable partial epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cost Control; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Vigabatrin | 1996 |
Important pharmacokinetic properties of antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Biopharmaceutics; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Intestinal Absorption; Lamotrigine; Oxcarbazepine; Topiramate; Triazines; Vigabatrin | 1995 |
Seizure control: how to use the new antiepileptic drugs in older patients.
Topics: Acetates; Age Factors; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Patient Selection; Seizures; Triazines; Vigabatrin | 1996 |
New antiepileptic drugs. II. Clinical use.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Felbamate; Forecasting; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin; Zonisamide | 1996 |
Diagnosis and treatment of epilepsy in children and adolescents.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Infant, Newborn; Lamotrigine; Triazines | 1996 |
Periodic limb movements of sleep and the restless legs syndrome.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Folic Acid; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Narcotics; Polysomnography; Restless Legs Syndrome; Sleep Wake Disorders; Vitamin E; Wakefulness | 1996 |
New antiepileptic drugs: a systematic review of their efficacy and tolerability.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cross-Over Studies; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Male; Middle Aged; Nipecotic Acids; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide | 1996 |
Update on the mechanism of action of antiepileptic drugs.
Topics: 4-Aminobutyrate Transaminase; Acetamides; Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Membrane Potentials; Mice; Neurotransmitter Agents; Nipecotic Acids; Phenethylamines; Phenylcarbamates; Propylene Glycols; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tiagabine; Topiramate; Triazines; Vigabatrin | 1996 |
Pharmacokinetics of new antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Carbamazepine; Cyclohexanecarboxylic Acids; Enzyme Induction; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1996 |
Clinical administration of new antiepileptic drugs: an overview of safety and efficacy.
Topics: Acetates; Amines; Anticonvulsants; Confidence Intervals; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Odds Ratio; Placebos; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 1996 |
The role of the old and the new antiepileptic drugs in special populations: mental and multiple handicaps.
Topics: Acetates; Amines; Anticonvulsants; Cerebral Palsy; Cyclohexanecarboxylic Acids; Disabled Persons; Drug Administration Schedule; Drug Interactions; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Phenylcarbamates; Polypharmacy; Propylene Glycols; Vigabatrin | 1996 |
[Advantages and disadvantages of new antiepileptic drugs].
Topics: Acetates; Adrenocorticotropic Hormone; Amines; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Valproic Acid; Vigabatrin | 1996 |
[Treatment of the epilepsy: new drugs].
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin; Zonisamide | 1996 |
The new antiepileptic drugs.
Topics: Abnormalities, Drug-Induced; Acetates; Adolescent; Adult; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Pregnancy; Propylene Glycols; Randomized Controlled Trials as Topic; Triazines; Vigabatrin | 1996 |
New antiepileptic drugs.
Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin | 1996 |
New antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1996 |
Pharmacokinetics and interaction profile of topiramate: review and comparison with other newer antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Topiramate; Triazines; Vigabatrin | 1997 |
Overview of the safety of newer antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1997 |
[New antiepileptic drugs].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenylcarbamates; Propylene Glycols; Vigabatrin | 1997 |
Pharmacologic and dietary therapies in epilepsy: conventional treatments and recent advances.
Topics: Acetates; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketone Bodies; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Triazines; Valproic Acid; Vigabatrin | 1997 |
Recent advancements in epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Neurosurgery; Phenylcarbamates; Phenytoin; Pia Mater; Propylene Glycols; Temporal Lobe; Topiramate; Triazines; Vigabatrin | 1997 |
Use of gabapentin in pain management.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Migraine Disorders; Pain | 1997 |
A review of the newer antiepileptic drugs and the ketogenic diet.
Topics: Acetates; Age Factors; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Ketone Bodies; Lamotrigine; Male; Phenylcarbamates; Propylene Glycols; Seizures; Triazines | 1997 |
Gabapentin for treatment of epilepsy in children.
Topics: Acetates; Adolescent; Adult; Amines; Animals; Anticonvulsants; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Disease Models, Animal; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1997 |
Overview of lamotrigine and the new antiepileptic drugs: the challenge.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Exanthema; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Treatment Outcome; Triazines; Valproic Acid; Vigabatrin | 1997 |
Mood stabilizer combinations: a review of safety and efficacy.
Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Calcium Channel Blockers; Clinical Trials as Topic; Clozapine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Risperidone; Valproic Acid | 1998 |
Newer antiepileptic drugs: gabapentin, lamotrigine, felbamate, topiramate and fosphenytoin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines | 1998 |
Advances in the medical treatment of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diazepam; Drug Approval; Drug Design; Drug Interactions; Drug Resistance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Ketones; Lamotrigine; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Phenylcarbamates; Phenytoin; Prodrugs; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Valproic Acid; Vigabatrin | 1998 |
A summary of mechanistic hypotheses of gabapentin pharmacology.
Topics: Acetates; Amines; Analgesics; Animals; Anti-Anxiety Agents; Anticonvulsants; Brain; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Neurological; Neuroprotective Agents; Neurotransmitter Agents; Pain; Sodium Channels; Synapses; Tissue Distribution | 1998 |
Measuring human brain GABA in vivo: effects of GABA-transaminase inhibition with vigabatrin.
Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Anticonvulsants; Brain; Brain Chemistry; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Neurological; Vigabatrin | 1998 |
Anticonvulsant therapy in small animals.
Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Clonazepam; Clorazepate Dipotassium; Cyclohexanecarboxylic Acids; Diazepam; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Mephenytoin; Pentobarbital; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Seizures; Valproic Acid | 1998 |
Monotherapy clinical trials of new antiepileptic drugs: design, indications, and controversies.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Approval; Drug Design; Drug Therapy, Combination; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Placebos; Research Design; Treatment Failure; Treatment Outcome; United States; United States Food and Drug Administration | 1997 |
The new antiepileptic drugs: a systematic review of their efficacy and tolerability.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Male; Middle Aged; Randomized Controlled Trials as Topic; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide | 1997 |
Antiepileptic drug review: part 2.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Cyclohexanecarboxylic Acids; Drug Interactions; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines | 1998 |
Aggravation of focal epileptic seizures by antiepileptic drugs.
Topics: Acetates; Acute Disease; Adult; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Epilepsies, Partial; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenylcarbamates; Propylene Glycols; Vigabatrin | 1998 |
A mechanistic approach to antiepileptic drug interactions.
Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 1998 |
Special considerations: use of lithium in children, adolescents, and elderly populations.
Topics: Abnormalities, Drug-Induced; Acetates; Adolescent; Adult; Age Factors; Aged; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Male; Pregnancy; Triazines; Valproic Acid | 1998 |
Anticonvulsants and antipsychotics in the treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines | 1998 |
Mechanisms of action of gabapentin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents | 1997 |
New antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Vigabatrin | 1998 |
Antiepileptic drug therapy.
Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Cat Diseases; Cats; Cyclohexanecarboxylic Acids; Diazepam; Dog Diseases; Dogs; Drug Resistance; Emergency Treatment; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Phenobarbital; Phenylcarbamates; Potassium Compounds; Propylene Glycols; Seizures | 1998 |
Cellular and molecular actions of lamotrigine: Possible mechanisms of efficacy in bipolar disorder.
Topics: Acetates; Action Potentials; Amines; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Calcium Channel Blockers; Carrier Proteins; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Lamotrigine; Limbic System; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neural Inhibition; Neuronal Plasticity; Serotonin Plasma Membrane Transport Proteins; Signal Transduction; Sodium Channels; Synaptic Transmission; Triazines; Valproic Acid | 1998 |
Gabapentin. Antiepileptic mechanism of action.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Calcium Channels; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Neural Inhibition; Receptors, GABA; Receptors, Glutamate; Sodium Channels; Synaptic Transmission | 1998 |
Lamotrigine and gabapentin. Alternative in the treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Treatment Outcome; Triazines | 1998 |
Fortnightly review: drug treatment of epilepsy.
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Clobazam; Clonazepam; Cyclohexanecarboxylic Acids; Diethylcarbamazine; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Topiramate; Valproic Acid; Vigabatrin | 1999 |
New medication options for patients with epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines | 1998 |
Neuropharmacologic aspects of the ocular motor system and the treatment of abnormal eye movements.
Topics: Abducens Nerve; Acetates; Amines; Baclofen; Cranial Nerve Diseases; Cyclohexanecarboxylic Acids; Eye Movements; Fixation, Ocular; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoglossal Nerve; Ocular Motility Disorders; Vestibular Nerve; Visual Pathways | 1999 |
3-substituted GABA analogs with central nervous system activity: a review.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Structure-Activity Relationship | 1999 |
Carrell-Krusen Symposium invited lecture. Clinical trials in motor neuron diseases.
Topics: Acetates; Adolescent; Adult; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain-Derived Neurotrophic Factor; Child; Child, Preschool; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Guidelines as Topic; Humans; Infant; Insulin-Like Growth Factor I; Male; Mice; Middle Aged; Motor Neuron Disease; Muscular Atrophy, Spinal; Nerve Growth Factors; Outcome Assessment, Health Care; Postpoliomyelitis Syndrome; Riluzole | 1999 |
Gabapentin: a review of published experience in the treatment of bipolar disorder and other psychiatric conditions.
Topics: Acetates; Amines; Anticonvulsants; Anxiety; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Psychotic Disorders; Substance-Related Disorders | 1999 |
New antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Practice Guidelines as Topic; Topiramate; Triazines; Vigabatrin | 1999 |
New antiepileptic drugs: comparison of key clinical trials.
Topics: Acetates; Amines; Anticonvulsants; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Placebos; Research Design; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin | 1999 |
A new twist for stopping the shakes? Revisiting GABAergic therapy for essential tremor.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Primidone; Propranolol; Tremor | 1999 |
Treatment of chronic pain with antiepileptic drugs: a new era.
Topics: Acetates; Amines; Analgesics; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neurons, Afferent; Nociceptors; Pain; Receptors, Opioid; Spinal Nerve Roots | 1999 |
Clinical experience using adjunctive gabapentin in treatment-resistant bipolar mixed states.
Topics: Acetates; Adjuvants, Pharmaceutic; Adult; Aged; Amines; Analysis of Variance; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome | 1999 |
Mechanisms of new antiepileptic drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Drug Industry; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Receptors, GABA; Receptors, GABA-A; Sodium Channel Blockers | 1999 |
Lamotrigine in the treatment of bipolar depression.
Topics: Acetates; Affect; Amines; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cross-Over Studies; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Triazines | 1999 |
Options after the first antiepileptic drug has failed.
Topics: Acetates; Amines; Anticonvulsants; Attitude to Health; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Quality of Life; Treatment Failure; Treatment Outcome; Valproic Acid; Vigabatrin | 1999 |
Monotherapy trials with gabapentin for partial epilepsy.
Topics: Acetates; Ambulatory Care; Amines; Anticonvulsants; Carbamazepine; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Multicenter Studies as Topic; Placebos; Randomized Controlled Trials as Topic; Treatment Outcome | 1999 |
Monostars: an aid to choosing an antiepileptic drug as monotherapy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Practice Patterns, Physicians'; Triazines; Valproic Acid; Vigabatrin | 1999 |
Use of new antiepileptic drugs in the treatment of childhood epilepsy.
Topics: Acetates; Adult; Age Factors; Amines; Anticonvulsants; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Spasms, Infantile; Tiagabine; Topiramate; Triazines; Vigabatrin | 1999 |
Gabapentin in the management of convulsive disorders.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Gabapentin; gamma-Aminobutyric Acid; Humans; Rats; Synaptic Transmission; Treatment Outcome | 1999 |
Postherpetic neuralgia: role of gabapentin and other treatment modalities.
Topics: Acetates; Administration, Topical; Age Factors; Aged; Ambulatory Care; Amines; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Capsaicin; Carbamazepine; Clinical Trials as Topic; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Narcotics; Neuralgia; Pain; Risk Factors; Severity of Illness Index; Treatment Outcome | 1999 |
Social phobia: issues in assessment and management.
Topics: Acetates; Amines; Anticonvulsants; Benzodiazepines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Monoamine Oxidase Inhibitors; Personality Inventory; Phobic Disorders; Psychiatric Status Rating Scales; Psychometrics; Selective Serotonin Reuptake Inhibitors | 1999 |
Nonepileptic uses of gabapentin.
Topics: Acetates; Amines; Analgesics; Antimanic Agents; Antiparkinson Agents; Bipolar Disorder; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Movement Disorders; Neuralgia; Restless Legs Syndrome; Spinal Cord Diseases; Treatment Outcome | 1999 |
Evidence-based medicine and antiepileptic drugs.
Topics: Acetates; Adult; Amines; Anticonvulsants; Confidence Intervals; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Electric Stimulation Therapy; Epilepsies, Partial; Evidence-Based Medicine; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Odds Ratio; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Triazines; Vagus Nerve | 1999 |
Gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dizziness; Drug Monitoring; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Product Surveillance, Postmarketing; Sleep Wake Disorders; Treatment Outcome | 1999 |
Therapeutic advances: new hope for patients with ALS.
Topics: Acetates; Aged; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Long-Term Care; Neuroprotective Agents; Patient Education as Topic; Riluzole | 1998 |
Managing pediatric epilepsy syndromes with new antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin | 1999 |
Voltage-dependent Ca2+ channel alpha2delta auxiliary subunit: structure, function and regulation.
Topics: Acetates; Amines; Animals; Calcium Channels; Cloning, Molecular; Cyclohexanecarboxylic Acids; Electrochemistry; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Kinetics; Models, Molecular; Protein Structure, Quaternary; Recombinant Proteins | 1999 |
Gabapentin and lamotrigine in bipolar disorder.
Topics: Acetates; Adult; Amines; Anticonvulsants; Bipolar Disorder; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Triazines | 1999 |
The clinical pharmacokinetics of the new antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Zonisamide | 1999 |
[Gabapentin in the treatment of polyneuropathy associated with the human immunodeficiency virus].
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; HIV Infections; HIV-1; Humans; Male; Polyneuropathies; Remission Induction | 1999 |
Interstitial cystitis and the potential role of gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Cystitis, Interstitial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain; Pain Clinics | 2000 |
Mood stabilizers during breastfeeding: a review.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Breast Feeding; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Infant, Newborn; Lamotrigine; Lithium; MEDLINE; Milk, Human; Pregnancy; Pregnancy Complications; Puerperal Disorders; Triazines; Valproic Acid | 2000 |
[GABA-ergic system and antiepileptic drugs].
Topics: Acetates; Amines; Anticonvulsants; Binding, Competitive; Calcium Channels; Chloride Channels; Cyclohexanecarboxylic Acids; Epilepsy; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Humans; Nipecotic Acids; Receptors, GABA; Sodium Channels; Tiagabine; Vigabatrin | 2000 |
Gabapentin for drug-resistant partial epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Failure | 2000 |
Gabapentin: a new tool in the treatment of neuropathic pain.
Topics: Acetates; Amines; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Treatment Outcome | 1999 |
New antiepileptic drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2000 |
Use of gabapentin in the treatment of neuropathic pain.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia | 2000 |
Tremor-predominant Parkinson's disease. Approaches to treatment.
Topics: Acetates; Amantadine; Amines; Antiparkinson Agents; Botulinum Toxins; Cholinergic Antagonists; Clonazepam; Clozapine; Cyclohexanecarboxylic Acids; Dopamine Agonists; Electric Stimulation Therapy; Gabapentin; Gamma Rays; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Neurosurgical Procedures; Parkinson Disease; Propranolol; Radiosurgery; Thalamus; Tremor | 2000 |
Gabapentin use in neuropathic pain syndromes.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Peripheral Nervous System Diseases; Proto-Oncogene Mas; Syndrome | 2000 |
[Current data on gabapentin].
Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Tolerance; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Outcome | 2000 |
Gabapentin add-on for drug-resistant partial epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Failure | 2000 |
Adjuvant therapy of melanoma with interferon-alpha-2b is associated with mania and bipolar syndromes.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Antimanic Agents; Antineoplastic Agents; Bipolar Disorder; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Depression; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Interferon alpha-2; Interferon-alpha; Male; Melanoma; Middle Aged; Mood Disorders; Prospective Studies; Recombinant Proteins | 2000 |
Gabapentin in pain management.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain | 2000 |
Drug treatment of benign focal epilepsies of childhood.
Topics: Acetates; Amines; Anticonvulsants; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Thiazines; Time Factors; Treatment Outcome | 2000 |
Painful trigeminal neuropathy caused by severe mandibular resorption and nerve compression in a patient with systemic sclerosis: case report and literature review.
Topics: Acetates; Adult; Amines; Analgesics; Anticonvulsants; Bone Resorption; CREST Syndrome; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mandibular Diseases; Mandibular Nerve; Nerve Compression Syndromes; Trigeminal Neuralgia | 2000 |
Therapeutic safety monitoring: what to look for and when to look for it.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2000 |
[Adverse effects of antiepileptic agents].
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Clobazam; Cyclohexanecarboxylic Acids; Drug Utilization; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Norway; Piracetam; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2000 |
New treatments of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Olanzapine; Phenytoin; Pirenzepine; Topiramate; Treatment Outcome; Triazines | 1999 |
New antiepileptic drugs and preparations.
Topics: Acetates; Administration, Rectal; Age Factors; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diazepam; Drug Overdose; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines; Valproic Acid | 2000 |
An ever-increasing pharmacopoeia for the management of patients with bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electroconvulsive Therapy; Electromagnetic Phenomena; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Olanzapine; Pirenzepine; Risperidone; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2000 |
[Gabapentin--yet another antiepileptic agent for the treatment of neuropathic pain?].
Topics: Acetates; Amines; Analgesics; Anticonvulsants; Clinical Trials as Topic; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Herpesviridae Infections; Humans; Multicenter Studies as Topic; Neuralgia | 2001 |
Pharmacotherapy of spasticity: oral medications and intrathecal baclofen.
Topics: Acetates; Administration, Oral; Amines; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Cerebral Palsy; Child, Preschool; Cyclohexanecarboxylic Acids; Dantrolene; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Muscle Relaxants, Central | 2001 |
[Gabapentin therapy for pain].
Topics: Acetates; Amines; Analgesics; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Migraine Disorders; Pain; Reflex Sympathetic Dystrophy; Trigeminal Neuralgia | 2001 |
Novel treatments for bipolar disorder.
Topics: Acetates; Amines; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Fatty Acids, Omega-3; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Topiramate; Triazines; Valproic Acid | 2001 |
Effects of antimanic mood-stabilizing drugs on fetuses, neonates, and nursing infants.
Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Antimanic Agents; Benzodiazepines; Breast Feeding; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Fetus; Gabapentin; gamma-Aminobutyric Acid; Haloperidol; Humans; Infant, Newborn; Lithium; Mood Disorders; Olanzapine; Pirenzepine; Placenta; Pregnancy; Risk Factors; Valproic Acid | 2001 |
Evidence for the use of gabapentin in the treatment of diabetic peripheral neuropathy.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Humans | 2001 |
Cognitive side effects of anticonvulsants.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Mood Disorders; Topiramate; Triazines; Valproic Acid | 2001 |
Gabapentin treatment for bipolar disorders.
Topics: Acetates; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Randomized Controlled Trials as Topic; Treatment Outcome | 2001 |
GABA agonists and gabapentin for spastic hypertonia.
Topics: Acetates; Amines; Animals; Anticonvulsants; Baclofen; Benzodiazepines; Cyclohexanecarboxylic Acids; Diazepam; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Muscle Spasticity | 2001 |
Gabapentin: a unique anti-epileptic agent.
Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Complex Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia | 2001 |
Gabapentin for neuropathic pain: systematic review of controlled and uncontrolled literature.
Topics: Acetates; Amines; Analgesics; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Randomized Controlled Trials as Topic; Treatment Outcome | 2001 |
[Gabapentin for therapy of neuropathic pain].
Topics: Acetates; Amines; Animals; Biological Availability; Brain; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain Threshold; Spinal Cord | 2001 |
Complex regional pain syndrome.
Topics: Acetates; Algorithms; Amines; Anesthesia, Conduction; Anesthetics, Local; Anti-Inflammatory Agents; Antidepressive Agents; Autonomic Nerve Block; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Decision Trees; Electromyography; Gabapentin; gamma-Aminobutyric Acid; Humans; Patient Care Team; Patient Selection; Physical Therapy Modalities; Referral and Consultation; Thermography; Treatment Outcome | 2002 |
Management of spasticity, pain, and paroxysmal phenomena in multiple sclerosis.
Topics: Acetates; Amines; Autoimmune Diseases; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Cannabinoids; Causalgia; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Dystonia; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Mechanoreceptors; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Pain; Physical Therapy Modalities; Receptors, GABA-A; Receptors, GABA-B; Relaxation Therapy; Trigeminal Neuralgia | 2001 |
Bipolar disorders and the effectiveness of novel anticonvulsants.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Topiramate; Triazines | 2002 |
The evolving role of topiramate among other mood stabilizers in the management of bipolar disorder.
Topics: Acetates; Acute Disease; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Randomized Controlled Trials as Topic; Topiramate; Triazines; Valproic Acid | 2001 |
Gabapentin: pharmacology and its use in pain management.
Topics: Acetates; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Nervous System Diseases; Pain; Pilot Projects; Pregnancy; Randomized Controlled Trials as Topic | 2002 |
Lamotrigine update and its use in mood disorders.
Topics: Acetates; Aggression; Amines; Antidepressive Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Depressive Disorder; Dermatitis, Exfoliative; Dizziness; Drug Interactions; Epilepsy; Exanthema; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Ion Channel Gating; Lamotrigine; Mood Disorders; Nausea; Randomized Controlled Trials as Topic; Sodium Channels; Triazines | 2002 |
Third generation anticonvulsants in bipolar disorder: a review of efficacy and summary of clinical recommendations.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Double-Blind Method; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Placebos; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2002 |
Pharmacokinetics of new anticonvulsants in psychiatry.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Mental Disorders; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Psychiatry; Tiagabine; Topiramate; Triazines | 1998 |
Anticonvulsants for neuropathic pain and detoxification.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clonazepam; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Inactivation, Metabolic; Lamotrigine; Neuralgia; Phenytoin; Substance Withdrawal Syndrome; Triazines; Valproic Acid | 1998 |
Bipolar disorder: current treatments and new strategies.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Mood Disorders; Topiramate; Treatment Outcome; Treatment Refusal; Triazines | 1998 |
Panic disorder and social phobia: current treatments and new strategies.
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Panic Disorder; Phobic Disorders; Selective Serotonin Reuptake Inhibitors | 1998 |
Background and rationale for use of anticonvulsants in psychiatry.
Topics: Acetates; Amines; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; History, 20th Century; Humans; Mental Disorders; Pain; Psychiatry | 1998 |
Gabapentin. Pfizer.
Topics: Acetates; Amines; Analgesics; Animals; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Contraindications; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Structure-Activity Relationship | 2002 |
Newer antiepileptic drugs in bipolar disorder: rationale for use and role in therapy.
Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Topiramate; Treatment Outcome; Triazines | 2002 |
Ca2+ channels and epilepsy.
Topics: Acetates; Amines; Calcium Channels; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Mutation | 2002 |
Use of anticonvulsants for treatment of neuropathic pain.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nervous System Diseases; Pain; Phenytoin; Triazines; Zonisamide | 2002 |
Mode of action of gabapentin in chronic neuropathic pain syndromes. A short review about its cellular mechanisms in nociceptive neurotransmission.
Topics: Acetates; Amines; Animals; Biogenic Monoamines; Calcium Channels; Chronic Disease; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Peripheral Nervous System Diseases; Synaptic Transmission | 2002 |
How can physicians and their patients with ALS decide to use the newly-available treatments to slow disease progression?
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Disease Progression; Gabapentin; gamma-Aminobutyric Acid; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Neuroprotective Agents; Quality of Life; Riluzole; Sickness Impact Profile | 1999 |
[Characteristics and indications of gabapentin].
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged | 2002 |
Antiepileptic drug therapy for adults: when to initiate and how to choose.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Recurrence; Risk Factors; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2002 |
The role of anticonvulsants in preventive migraine therapy.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Approval; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders; Recurrence; Topiramate; Treatment Outcome; Valproic Acid | 2003 |
Gabapentin for the treatment of tremor.
Topics: Acetates; Adult; Aged; Amines; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Parkinson Disease; Treatment Outcome; Tremor | 2003 |
Absence seizures in children.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid | 2002 |
New antiepileptic drug therapies.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Phenytoin; Piracetam; Propylene Glycols; Thiazines; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2002 |
Gabapentin dosing for neuropathic pain: evidence from randomized, placebo-controlled clinical trials.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Herpesviridae Infections; Humans; Neuralgia; Pain; Peripheral Nervous System Diseases; Randomized Controlled Trials as Topic; Syndrome | 2003 |
Antidepressant properties of anticonvulsant drugs for bipolar disorder.
Topics: Acetates; Affect; Amines; Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Topiramate; Triazines; Valproic Acid | 2003 |
Treatment and prevention of postherpetic neuralgia.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Lidocaine; Neuralgia; Randomized Controlled Trials as Topic | 2003 |
The role of GABA in anxiety disorders.
Topics: Acetates; Amines; Anxiety Disorders; Benzodiazepines; Cyclohexanecarboxylic Acids; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Nipecotic Acids; Receptors, GABA-A; Synaptic Transmission; Tiagabine | 2003 |
Treating bipolar depression.
Topics: Acetates; Affect; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium Compounds; Nipecotic Acids; Olanzapine; Oxcarbazepine; Pirenzepine; Tiagabine; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Zonisamide | 2003 |
Clinical inquiries. What nonhormonal therapies are effective for postmenopausal vasomotor symptoms?
Topics: Acetates; Amines; Cimicifuga; Clonidine; Contraindications; Cyclohexanecarboxylic Acids; Estrogens, Non-Steroidal; Evidence-Based Medicine; Exercise; Female; Gabapentin; gamma-Aminobutyric Acid; Hormone Replacement Therapy; Hot Flashes; Humans; Isoflavones; Middle Aged; Phytoestrogens; Phytotherapy; Plant Preparations; Postmenopause; Practice Guidelines as Topic; Selective Serotonin Reuptake Inhibitors; Soybean Proteins | 2003 |
Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Donepezil; Fatty Acids, Omega-3; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Lamotrigine; Lithium Carbonate; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Risperidone; Thiazoles; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2003 |
The clinical use of gabapentin in bipolar spectrum disorders.
Topics: Acetates; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans | 2003 |
Cellular and molecular action of the putative GABA-mimetic, gabapentin.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Anxiety; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Neurotransmitter Agents; Pain; Rats; Seizures; Signal Transduction | 2003 |
The role of gabapentin in treating diseases with cutaneous manifestations and pain.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Pain; Skin Diseases | 2003 |
Neuropathic cranial pain.
Topics: Acetates; Amines; Analgesics; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Fructose; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Lamotrigine; Nervous System Diseases; Phenytoin; Topiramate; Triazines | 2003 |
The use of gabapentin for the treatment of postherpetic neuralgia.
Topics: Acetates; Amines; Analgesics; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Pain Measurement | 2003 |
Gabapentin dosing in the treatment of epilepsy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 2003 |
Tremor.
Topics: Acetates; Amines; Anticonvulsants; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Electromyography; Essential Tremor; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Levodopa; Motor Cortex; Muscle, Skeletal; Parkinson Disease; Posture; Primidone; Randomized Controlled Trials as Topic; Severity of Illness Index; Somatosensory Cortex; Topiramate; Tremor | 2003 |
Gabapentin and lamotrigine: novel antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Intestinal Absorption; Lamotrigine; Tissue Distribution; Triazines | 1995 |
Essential tremor: differential diagnosis and current therapy.
Topics: Acetates; Adrenergic beta-Antagonists; Amines; Anti-Dyskinesia Agents; Anticonvulsants; Benzodiazepines; Botulinum Toxins; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Electric Stimulation Therapy; Essential Tremor; Ethanol; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Primidone; Thalamus; Topiramate | 2003 |
Pharmacological treatment of social anxiety disorder: a meta-analysis.
Topics: Acetates; Amines; Anti-Anxiety Agents; Antidepressive Agents; Antimanic Agents; Anxiety Disorders; Calcium Channel Blockers; Clonazepam; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Monoamine Oxidase Inhibitors; Phenelzine; Phobic Disorders; Piperidines; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 2003 |
The ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come?
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2003 |
Essential tremor: diagnosis and treatment.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Essential Tremor; Gabapentin; gamma-Aminobutyric Acid; Humans; Parkinson Disease; Primidone; Propranolol | 2003 |
Gabapentin: in postherpetic neuralgia.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia | 2003 |
Gabapentin: a viewpoint by Brett R. Stacey.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia | 2003 |
Gabapentin: a viewpoint by Ian Gilron.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain | 2003 |
Assessment and treatment of hot flushes and menopausal mood disturbance.
Topics: Acetates; Aging; Amines; Anti-Anxiety Agents; Cognition Disorders; Cyclohexanecarboxylic Acids; Female; Follicle Stimulating Hormone; Gabapentin; gamma-Aminobutyric Acid; Hormone Replacement Therapy; Hot Flashes; Humans; Menopause; Middle Aged; Mood Disorders; Randomized Controlled Trials as Topic; Sleep Wake Disorders | 2003 |
Alternatives to estrogen.
Topics: Acetates; Acupuncture Therapy; Adrenergic alpha-Agonists; Amines; Antidepressive Agents, Second-Generation; Antioxidants; Behavior Therapy; Belladonna Alkaloids; Cimicifuga; Cyclohexanecarboxylic Acids; Dietary Supplements; Drug Combinations; Ergotamines; Estrogen Replacement Therapy; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Isoflavones; Menopause; Methysergide; Phenobarbital; Phytoestrogens; Plant Preparations; Selective Serotonin Reuptake Inhibitors; Sulpiride; United States; Vitamin E; Women's Health | 2003 |
[Anticonvulsants in preventive therapy of migraine].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders; Topiramate; Valproic Acid | 2003 |
Use of gabapentin for postherpetic neuralgia: results of two randomized, placebo-controlled studies.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Randomized Controlled Trials as Topic | 2003 |
[Nonorganic pain -- only psychogenic?].
Topics: Acetates; Adult; Amines; Analgesics; Analgesics, Opioid; Anesthetics, Local; Back Pain; Chronic Disease; Cicatrix; Complementary Therapies; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Migraine Disorders; Nociceptors; Pain; Pain Management; Physical Therapy Modalities; Procaine; Reflex Sympathetic Dystrophy; Tramadol | 2003 |
The new antiepileptic drugs: scientific review.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Zonisamide | 2004 |
A critical review of atypical antipsychotic utilization: comparing monotherapy with polypharmacy and augmentation.
Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Clinical Trials as Topic; Clozapine; Cyclohexanecarboxylic Acids; Drug Utilization; Gabapentin; gamma-Aminobutyric Acid; Humans; Polypharmacy; Risperidone; Schizophrenia; Valproic Acid | 2004 |
Gabapentin in the treatment of neuropathic pain.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Pain Measurement; Peripheral Nervous System Diseases; Randomized Controlled Trials as Topic | 2004 |
Making sense of the evidence regarding nonhormonal treatments for hot flashes.
Topics: Acetates; Activities of Daily Living; Algorithms; Amines; Cyclohexanecarboxylic Acids; Cyclohexanols; Decision Trees; Drug Monitoring; Drug Therapy, Combination; Evidence-Based Medicine; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Middle Aged; Nursing Assessment; Patient Selection; Quality of Life; Selective Serotonin Reuptake Inhibitors; Self Care; Severity of Illness Index; Treatment Outcome; Venlafaxine Hydrochloride | 2004 |
A GABA(B) mystery: the search for pharmacologically distinct GABA(B) receptors.
Topics: Acetates; Amines; Animals; Anticonvulsants; Baclofen; Benzylamines; Cyclohexanecarboxylic Acids; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Molecular Structure; Morpholines; Phosphinic Acids; Protein Isoforms; Receptors, GABA-B; RNA, Messenger | 2001 |
Gabapentin as a drug therapy of intractable hiccup because of vascular lesion: a three-year follow up.
Topics: Acetates; Aged; Amines; Brain Stem; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Magnetic Resonance Imaging; Male; Stroke | 2004 |
Calcium channel alpha2delta subunits: differential expression, function, and drug binding.
Topics: Acetates; Amines; Amino Acid Sequence; Animals; Calcium Channel Blockers; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation; Humans; Membrane Potentials; Molecular Sequence Data; Mutation; Protein Structure, Quaternary; Recombinant Proteins; Structure-Activity Relationship | 2003 |
New pharmacologic targets for the treatment of the overactive bladder: an update.
Topics: Acetates; Amines; Animals; Botulinum Toxins; Central Nervous System Agents; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Humans; Narcotics; Nociceptin Receptor; Receptors, Adrenergic; Receptors, Drug; Receptors, Opioid; Serotonin Antagonists; Tramadol; Urinary Incontinence | 2004 |
Diagnosis and management of neuropathic pain: a balanced approach to treatment.
Topics: Acetates; Amines; Antidepressive Agents; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Lidocaine; Narcotics; Neuralgia; Nurse Practitioners; Pain Measurement; Prevalence | 2003 |
Post-herpetic neuralgia case study: optimizing pain control.
Topics: Acetates; Aged; Amines; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Depression; Disease Management; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Herpes Zoster; Herpesvirus 3, Human; Humans; Male; Neuralgia; Pain; Quality of Life | 2004 |
Efficacy and tolerability of the new antiepileptic drugs, I: Treatment of new-onset epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society.
Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Antipsychotic Agents; Carbamazepine; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; United States; United States Food and Drug Administration; Zonisamide | 2004 |
Efficacy and tolerability of the new antiepileptic drugs, II: Treatment of refractory epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society.
Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Anticonvulsants; Carbamazepine; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsies, Partial; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Practice Patterns, Physicians'; Tiagabine; Topiramate; Triazines; United States; United States Food and Drug Administration; Zonisamide | 2004 |
Efficacy and tolerability of the new antiepileptic drugs I: treatment of new onset epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epileps
Topics: Acetates; Acute Disease; Adolescent; Adult; Amines; Anticonvulsants; Carbamazepine; Child; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Evidence-Based Medicine; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Topiramate; Treatment Outcome; Triazines | 2004 |
Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epile
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Resistance; Epilepsies, Partial; Epilepsy, Generalized; Evidence-Based Medicine; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2004 |
Management of hot flashes in breast cancer survivors and men with prostate cancer.
Topics: Amines; Anti-Anxiety Agents; Breast Neoplasms; Complementary Therapies; Contraceptives, Oral, Synthetic; Cyclohexanecarboxylic Acids; Cyclohexanols; Drug Therapy, Combination; Estrogen Replacement Therapy; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Male; Medroxyprogesterone; Menopause, Premature; Paroxetine; Prostatic Neoplasms; Quality of Life; Selective Serotonin Reuptake Inhibitors; Survivors; Treatment Outcome; Venlafaxine Hydrochloride | 2004 |
Newer anticonvulsants in the treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Depressive Disorder; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2004 |
80-year-old man with fever and ear pain.
Topics: Acetates; Acyclovir; Age Factors; Aged; Aged, 80 and over; Amines; Analgesics; Antiviral Agents; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Earache; Fever; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Oxycodone; Pain; Patient Selection; Polymerase Chain Reaction; Risk Factors; Valacyclovir; Valine | 2004 |
Gabapentin for intractable hiccup.
Topics: Acetates; Aged; Amines; Baclofen; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Hiccup; Humans; Male; Muscle Relaxants, Central; Tomography, X-Ray Computed | 2004 |
'Protective premedication': an option with gabapentin and related drugs? A review of gabapentin and pregabalin in in the treatment of post-operative pain.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Pain, Postoperative; Peripheral Nervous System Diseases; Pregabalin; Randomized Controlled Trials as Topic | 2004 |
Rethinking the treatment paradigm for bipolar depression: the importance of long-term management.
Topics: Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Chronic Disease; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium Carbonate; Randomized Controlled Trials as Topic; Time; Topiramate; Triazines; Valproic Acid | 2004 |
Antispasticity medications: uses and limitations of enteral therapy.
Topics: 4-Aminopyridine; Acetates; Adrenergic alpha-Agonists; Amines; Baclofen; Benzodiazepines; Cyclohexanecarboxylic Acids; Cyproheptadine; Dantrolene; Dronabinol; Gabapentin; gamma-Aminobutyric Acid; Glycine; Humans; Muscle Relaxants, Central; Muscle Spasticity; Neuroprotective Agents; Piracetam; Serotonin Antagonists | 2004 |
Practice parameter: treatment of postherpetic neuralgia: an evidence-based report of the Quality Standards Subcommittee of the American Academy of Neurology.
Topics: Acupuncture Analgesia; Administration, Cutaneous; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Anticonvulsants; Antidepressive Agents, Tricyclic; Antiviral Agents; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Evaluation; Evidence-Based Medicine; Excitatory Amino Acid Antagonists; Forecasting; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Iontophoresis; Lidocaine; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic; Receptors, N-Methyl-D-Aspartate | 2004 |
Anticonvulsant drugs in primary headaches prophylaxis.
Topics: Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Oxcarbazepine; Piracetam; Topiramate; Triazines; Valproic Acid; Vigabatrin; Zonisamide | 2004 |
Absence seizures in children.
Topics: Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid | 2003 |
Postherpetic neuralgia.
Topics: 2-Aminopurine; Acyclovir; Adrenal Cortex Hormones; Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Antidepressive Agents, Tricyclic; Antiviral Agents; Cyclohexanecarboxylic Acids; Famciclovir; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Idoxuridine; Neuralgia | 2003 |
Gabapentin: a pooled analysis of adverse events from three clinical trials in patients with postherpetic neuralgia.
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Edema; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Neuralgia; Randomized Controlled Trials as Topic | 2004 |
Tolerability of treatments for postherpetic neuralgia.
Topics: Amines; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Herpesvirus 3, Human; Humans; Neuralgia; Nortriptyline; Treatment Outcome | 2004 |
Management issues of neuropathic trigeminal pain from a medical perspective.
Topics: Amines; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents; Baclofen; Carbamazepine; Cranial Nerve Injuries; Cyclohexanecarboxylic Acids; Facial Neuralgia; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Lamotrigine; Narcotics; Phenytoin; Triazines; Trigeminal Nerve Injuries; Trigeminal Neuralgia | 2004 |
Absence seizures in children.
Topics: Adolescent; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid | 2004 |
Pharmacology of vertigo/nystagmus/oscillopsia.
Topics: Amines; Benzodiazepines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Motion Perception; Nystagmus, Pathologic; Potassium Channel Blockers; Steroids; Vertigo; Vestibular Diseases; Vision Disorders | 2005 |
[Evidence-based pharmacotherapy of neuropathic pain syndromes].
Topics: Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Antioxidants; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Pain; Peripheral Nervous System Diseases; Placebos; Polyneuropathies; Randomized Controlled Trials as Topic; Reflex Sympathetic Dystrophy; Thioctic Acid; Trigeminal Neuralgia | 2004 |
Lamotrigine and antiepileptic drugs as mood stabilizers in bipolar disorder.
Topics: Acute Disease; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Randomized Controlled Trials as Topic; Secondary Prevention; Triazines; Valproic Acid | 2005 |
Postherpetic neuralgia.
Topics: 2-Aminopurine; Acyclovir; Amines; Antidepressive Agents, Tricyclic; Antiviral Agents; Arabinofuranosyluracil; Cyclohexanecarboxylic Acids; Famciclovir; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Valacyclovir; Valine | 2004 |
Optimal seizure management in brain tumor patients.
Topics: Amines; Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Levetiracetam; Piracetam; Retrospective Studies; Seizures | 2005 |
Novel anticonvulsants in the treatment of alcoholism.
Topics: Alcohol Deterrents; Alcoholism; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Ethanol; Gabapentin; gamma-Aminobutyric Acid; Humans; Randomized Controlled Trials as Topic; Secondary Prevention; Substance Withdrawal Syndrome; Valproic Acid | 2005 |
[Progress on painful diabetic peripheral neuropathy treated by integrative medicine].
Topics: Amines; Amitriptyline; Analgesics; Animals; Antidepressive Agents, Tricyclic; Blood Glucose; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Therapy, Combination; Drugs, Chinese Herbal; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Pain; Pain Measurement; Phytotherapy; Triazines | 2005 |
Treatment of hot flushes in breast and prostate cancer.
Topics: Amines; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cimicifuga; Contraindications; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electroacupuncture; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hormone Replacement Therapy; Hot Flashes; Humans; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Paroxetine; Phytotherapy; Plant Preparations; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors | 2005 |
[Symptomatic treatment of painful diabetic neuropathy].
Topics: Amines; Anti-Asthmatic Agents; Anticonvulsants; Antidepressive Agents; Antitussive Agents; Cyclohexanecarboxylic Acids; Dextromethorphan; Diabetic Neuropathies; Fructose; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Humans; Lamotrigine; Mexiletine; Nerve Fibers; Posterior Horn Cells; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sodium Channels; Topiramate; Triazines | 2005 |
Anticonvulsant drug therapies.
Topics: Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Depressive Disorder; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nurse's Role; Oxcarbazepine; Patient Selection; Safety; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Zonisamide | 2005 |
Anticonvulsant drugs for acute and chronic pain.
Topics: Acute Disease; Amines; Anticonvulsants; Chronic Disease; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Randomized Controlled Trials as Topic | 2005 |
Gabapentin for acute and chronic pain.
Topics: Acute Disease; Amines; Analgesics; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Nervous System Diseases; Neuralgia; Pain | 2005 |
Newer antidepressants and other nonhormonal agents for the treatment of hot flashes.
Topics: Adrenergic alpha-Agonists; Amines; Anti-Anxiety Agents; Antidepressive Agents; Antioxidants; Cimicifuga; Clonidine; Cyclohexanecarboxylic Acids; Drug Interactions; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Isoflavones; Phytotherapy; Vitamin E | 2005 |
Absence seizures in children.
Topics: Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy, Absence; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Valproic Acid | 2005 |
Combination pharmacotherapy for neuropathic pain: current evidence and future directions.
Topics: Amines; Analgesics; Animals; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Synergism; Drug Therapy, Combination; Expert Testimony; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; Pain; Peripheral Nervous System Diseases | 2005 |
How modeling and simulation have enhanced decision making in new drug development.
Topics: Alzheimer Disease; Amines; Animals; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Computer Simulation; Cyclohexanecarboxylic Acids; Decision Making, Computer-Assisted; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Herpesviridae Infections; Humans; Models, Statistical; Neuralgia; Pharmacology; Software | 2005 |
[The treatment of mood stabilizers in children and adolescents suffering from bipolar affective disorder].
Topics: Adolescent; Adult; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Child; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Topiramate; Triazines | 2005 |
The mechanisms of action of gabapentin and pregabalin.
Topics: Amines; Amino Acid Transport Systems; Analgesics; Animals; Anticonvulsants; Calcium Channels; Central Nervous System; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Pregabalin; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate | 2006 |
The mechanism of action of gabapentin in neuropathic pain.
Topics: Amines; Analgesics, Non-Narcotic; Animals; Binding Sites; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Peripheral Nervous System Diseases; Potassium Channels; Receptors, Neurotransmitter; Serotonin | 2006 |
Mechanisms of the antinociceptive action of gabapentin.
Topics: Amines; Analgesics; Animals; Anticonvulsants; Calcium Channels, N-Type; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Receptors, GABA-B | 2006 |
Gabapentin for pain: balancing benefit and harm.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Randomized Controlled Trials as Topic | 2006 |
Pregabalin in neuropathic pain: a more "pharmaceutically elegant" gabapentin?
Topics: Aged; Amines; Analgesics, Non-Narcotic; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Peripheral Nervous System Diseases; Pregabalin | 2005 |
The emergence of new drugs for overactive bladder.
Topics: Acetylcholine; Amines; Animals; Anticonvulsants; Benzhydryl Compounds; Cresols; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; Humans; Mandelic Acids; Muscarinic Antagonists; Muscle, Smooth; Phenylpropanolamine; Product Surveillance, Postmarketing; Quinuclidines; Randomized Controlled Trials as Topic; Receptor, Muscarinic M3; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urinary Incontinence | 2006 |
Analgesic treatment after laparoscopic cholecystectomy: a critical assessment of the evidence.
Topics: Amines; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, Laparoscopic; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Receptors, N-Methyl-D-Aspartate | 2006 |
Management of restless legs syndrome in patients on dialysis.
Topics: Amines; Anticonvulsants; Benzothiazoles; Clonazepam; Cyclohexanecarboxylic Acids; Dopamine Agents; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Levodopa; Narcotics; Pramipexole; Renal Dialysis; Restless Legs Syndrome; Thiazoles; Uremia | 2006 |
Postherpetic neuralgia.
Topics: 2-Aminopurine; Acyclovir; Amines; Antidepressive Agents, Tricyclic; Antiviral Agents; Arabinofuranosyluracil; Cyclohexanecarboxylic Acids; Famciclovir; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia, Postherpetic; Valacyclovir; Valine | 2005 |
Preoperative gabapentin for postoperative analgesia: a meta-analysis.
Topics: Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; Pain Measurement; Pain, Postoperative; Placebos; Premedication; Prospective Studies; Randomized Controlled Trials as Topic; Treatment Outcome | 2006 |
Nonhormonal therapies for menopausal hot flashes: systematic review and meta-analysis.
Topics: Adrenergic alpha-Agonists; Amines; Antidepressive Agents; Clonidine; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Glycine max; Hot Flashes; Humans; Isoflavones; Menopause; Plant Extracts; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Trifolium | 2006 |
New antiepileptic drugs that are second generation to existing antiepileptic drugs.
Topics: Amines; Animals; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Design; Drug Evaluation, Preclinical; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Molecular Structure; Randomized Controlled Trials as Topic; Structure-Activity Relationship; Valproic Acid | 2006 |
Gabapentin and postoperative pain--a systematic review of randomized controlled trials.
Topics: Acute Disease; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Perioperative Care; Randomized Controlled Trials as Topic | 2006 |
Narrative review: the promotion of gabapentin: an analysis of internal industry documents.
Topics: Advisory Committees; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Industry; Education, Medical, Continuing; Gabapentin; gamma-Aminobutyric Acid; Marketing; Publishing; Research | 2006 |
Systemic analgesia and co-analgesia.
Topics: Amines; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Dexmedetomidine; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Lidocaine; Narcotic Antagonists; Pain, Postoperative | 2006 |
Bilateral SUNCT syndrome associated to chronic maxillary sinus disease.
Topics: Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Male; Maxillary Sinusitis; Middle Aged; SUNCT Syndrome | 2006 |
Novel anticonvulsant drugs.
Topics: Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Piracetam; Pregabalin; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2007 |
Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed?
Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Pregabalin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2006 |
alpha2delta and the mechanism of action of gabapentin in the treatment of pain.
Topics: Amines; Analgesics; Animals; Brain; Calcium Channels; Cyclohexanecarboxylic Acids; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Pain; Radiography; Rats; Swine | 2006 |
Strategies of the Tinnitus Research Consortium.
Topics: Amines; Analgesics; Biomedical Research; Consensus; Cyclohexanecarboxylic Acids; Electric Stimulation Therapy; Gabapentin; gamma-Aminobutyric Acid; Health Planning; Humans; Neuronal Plasticity; Selective Serotonin Reuptake Inhibitors; Tinnitus | 2006 |
Pharmacology and mechanism of action of pregabalin: the calcium channel alpha2-delta (alpha2-delta) subunit as a target for antiepileptic drug discovery.
Topics: Amines; Amino Acid Sequence; Animals; Anticonvulsants; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Gabapentin; gamma-Aminobutyric Acid; Molecular Sequence Data; Pregabalin; Protein Conformation | 2007 |
Therapeutic management of chronic neuropathic pain: an examination of pharmacologic treatment.
Topics: Amines; Analgesics; Antidepressive Agents, Tricyclic; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia | 2006 |
Treatment of restless legs syndrome.
Topics: Amines; Analgesics, Opioid; Anticonvulsants; Cyclohexanecarboxylic Acids; Dopamine Agents; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Levodopa; Randomized Controlled Trials as Topic; Restless Legs Syndrome | 2006 |
Adjuvant analgesics for the treatment of neuropathic pain: evaluating efficacy and safety profiles.
Topics: Administration, Cutaneous; Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents; Arthritis; Chemotherapy, Adjuvant; Chronic Disease; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Diagnosis, Differential; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Low Back Pain; Pain; Pain Measurement; Pain, Postoperative; Practice Guidelines as Topic; Pregabalin; Wounds and Injuries | 2007 |
[A new aspect in the research on antiepileptic drugs].
Topics: Acetamides; Amines; Animals; Anticonvulsants; Benzodiazepines; Carbamates; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Humans; Lacosamide; Levetiracetam; Phenylenediamines; Piracetam; Pregabalin; Pregnanolone; Pyrrolidinones; Triazoles | 2007 |
[Newer antiepileptic drugs].
Topics: Amines; Animals; Anti-Anxiety Agents; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Approval; Drug Design; Drug Interactions; Epilepsy; Felbamate; Fructose; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Neuroprotective Agents; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Sodium Channel Blockers; Topiramate; Triazines; Zonisamide | 2007 |
Lamotrigine therapy in elderly patients with epilepsy, bipolar disorder or dementia.
Topics: Aged; Aged, 80 and over; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Dementia; Double-Blind Method; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Randomized Controlled Trials as Topic; Treatment Outcome; Triazines | 2007 |
Antiepileptic drugs in migraine: from clinical aspects to cellular mechanisms.
Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders; Topiramate; Valproic Acid | 2007 |
Treating vasomotor symptoms of menopause: the nurse practitioner's perspective.
Topics: Adrenergic alpha-Agonists; Algorithms; Amines; Citalopram; Clonidine; Complementary Therapies; Cyclohexanecarboxylic Acids; Estrogen Replacement Therapy; Evidence-Based Medicine; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Life Style; Menopause; Middle Aged; Nurse Practitioners; Paroxetine; Patient Education as Topic; Patient Selection; Practice Guidelines as Topic; Primary Health Care; Safety Management; Selective Serotonin Reuptake Inhibitors | 2007 |
Antiepileptic drugs for the treatment of chronic and episodic cluster headache: a review.
Topics: Amines; Anticonvulsants; Cluster Headache; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Receptors, GABA; Topiramate; Treatment Outcome; Valproic Acid | 2007 |
Safety and efficacy of anticonvulsants in elderly patients with psychiatric disorders: oxcarbazepine, topiramate and gabapentin.
Topics: Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Mental Disorders; Oxcarbazepine; Topiramate | 2007 |
[Epilepsy in the elderly].
Topics: Aged; Aged, 80 and over; Aging; Amines; Anticonvulsants; Cerebrovascular Disorders; Comorbidity; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Drug Interactions; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Levetiracetam; Pharmacokinetics; Piracetam | 2007 |
Functional biology of the alpha(2)delta subunits of voltage-gated calcium channels.
Topics: Amines; Animals; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebellar Ataxia; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Mice; Neuralgia; Protein Subunits | 2007 |
[A novel antiepileptic, gabapentin (GABAPEN)].
Topics: Amines; Animals; Anticonvulsants; Brain; Calcium Channels; Clinical Trials, Phase III as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Epilepsies, Partial; GABA Plasma Membrane Transport Proteins; Gabapentin; gamma-Aminobutyric Acid; Humans; Protein Binding | 2007 |
[Burning mouth syndrome].
Topics: Age Factors; Aged; Amines; Analgesics; Anti-Anxiety Agents; Antioxidants; Burning Mouth Syndrome; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Male; Middle Aged; Prevalence; Sex Factors; Thioctic Acid; Vitamin B Complex | 2007 |
Therapeutic options for the management of hot flashes in breast cancer survivors: an evidence-based review.
Topics: Amines; Antidepressive Agents; Breast Neoplasms; Complementary Therapies; Cyclohexanecarboxylic Acids; Estrogen Replacement Therapy; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Menopause, Premature; Randomized Controlled Trials as Topic; Survivors | 2007 |
Postoperative pain--clinical implications of basic research.
Topics: Amines; Analgesia; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Pain, Postoperative; Pregabalin; Receptors, N-Methyl-D-Aspartate | 2007 |
Useful adjuvants for postoperative pain management.
Topics: Amines; Clonidine; Cyclohexanecarboxylic Acids; Dexamethasone; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Neostigmine; Pain, Postoperative; Receptors, N-Methyl-D-Aspartate | 2007 |
Ca2+ channel alpha2-delta ligands for the treatment of neuropathic pain.
Topics: Amines; Analgesics; Animals; Anticonvulsants; Calcium Channels; Carboxylic Acids; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Mice; Mice, Mutant Strains; Pain; Peripheral Nervous System Diseases; Pregabalin; Prodrugs | 2007 |
The P/Q-type voltage-dependent calcium channel: a therapeutic target in spinocerebellar ataxia type 6.
Topics: Amines; Anticonvulsants; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Spinocerebellar Ataxias | 2007 |
Use of gabapentin for perioperative pain control -- a meta-analysis.
Topics: Adult; Amines; Analgesics; Confidence Intervals; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; MEDLINE; Middle Aged; Movement; Pain Measurement; Pain, Postoperative; Retrospective Studies; Sensitivity and Specificity; Time Factors | 2007 |
Do surgical patients benefit from perioperative gabapentin/pregabalin? A systematic review of efficacy and safety.
Topics: Amines; Cyclohexanecarboxylic Acids; Dizziness; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Perioperative Care; Pregabalin; Randomized Controlled Trials as Topic | 2007 |
Model-based drug development.
Topics: Alzheimer Disease; Amines; Analgesics; Animals; Anticholesteremic Agents; Bridged Bicyclo Compounds, Heterocyclic; Caproates; Cholesterol; Clinical Trials as Topic; Cognition; Computer Simulation; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Approval; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Glycoproteins; Guidelines as Topic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunologic Factors; Meta-Analysis as Topic; Models, Biological; Models, Statistical; Muscarinic Agonists; Neuralgia, Postherpetic; Neutrophil Infiltration; Oximes; Pharmacokinetics; Pharmacology; Reproducibility of Results; Research Design; Stroke; United States; United States Food and Drug Administration | 2007 |
Ketamine: an introduction for the pain and palliative medicine physician.
Topics: Adult; Amines; Analgesics; Analgesics, Opioid; Central Nervous System; Cryoglobulinemia; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hepatitis C; Humans; Ketamine; Methadone; Methylphenidate; Oxycodone; Pain, Intractable; Receptors, N-Methyl-D-Aspartate; Treatment Outcome; Ulcer; Vasculitis | 2007 |
Antiepileptic drugs in the treatment of neuropathic pain.
Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Neuralgia; Oxcarbazepine; Peripheral Nervous System Diseases; Topiramate; Treatment Outcome; Triazines | 2007 |
Diabetic neuropathy: new strategies for treatment.
Topics: Aldehyde Reductase; Amines; Analgesics; Anticonvulsants; Antidepressive Agents; Antioxidants; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Thiamine; Thioctic Acid; Thiophenes | 2008 |
Non-hormonal therapy of post-menopausal vasomotor symptoms: a structured evidence-based review.
Topics: Amines; Cimicifuga; Clonidine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Middle Aged; Phytoestrogens; Phytotherapy; Plants, Medicinal; Randomized Controlled Trials as Topic; Trifolium | 2007 |
Pharmacological treatment of fibromyalgia and other chronic musculoskeletal pain.
Topics: Adrenergic Uptake Inhibitors; Amines; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Pregabalin; Selective Serotonin Reuptake Inhibitors; Tramadol; Treatment Outcome | 2007 |
A cost-effectiveness comparison of desipramine, gabapentin, and pregabalin for treating postherpetic neuralgia.
Topics: Aged; Amines; Analgesics; Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Desipramine; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Neuralgia, Postherpetic; Pregabalin; Randomized Controlled Trials as Topic; Severity of Illness Index | 2007 |
GABAergic drugs for the treatment of migraine.
Topics: Acute Disease; Amines; Animals; Cyclohexanecarboxylic Acids; Fructose; GABA Agents; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders; Neuroprotective Agents; Pregabalin; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Topiramate; Valproic Acid | 2007 |
The effect of analgesic technique on postoperative patient-reported outcomes including analgesia: a systematic review.
Topics: Acetaminophen; Amines; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Health Status Indicators; Humans; Infusions, Intralesional; Infusions, Intravenous; Ketamine; Nerve Block; Outcome Assessment, Health Care; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Practice Guidelines as Topic; Quality of Life; Surveys and Questionnaires; Treatment Outcome | 2007 |
[When the legs have to keep moving at night--the restless legs syndrome].
Topics: Adult; Amines; Analgesics, Opioid; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Dopamine Agonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Levodopa; Male; Middle Aged; Polysomnography; Pregnancy; Quality of Life; Restless Legs Syndrome; Sleep Wake Disorders; Time Factors | 2007 |
[Frequently occurring forms of dizziness and their treatment].
Topics: Amines; Anticonvulsants; Betahistine; Carbamazepine; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dizziness; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Memantine; Meniere Disease; Middle Aged; Migraine Disorders; Nystagmus, Physiologic; Syndrome; Time Factors; Vasodilator Agents; Vertigo; Vestibular Diseases; Vestibular Neuronitis | 2007 |
Gabapentin Extended-Release - Depomed: Gabapentin ER, Gabapentin Gastric Retention, Gabapentin GR.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain | 2007 |
[Neuromuscular disorders caused by adverse effects of antiepileptics].
Topics: Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Neuromuscular Diseases; Phenobarbital; Phenytoin; Topiramate; Valproic Acid; Zonisamide | 2007 |
Gabapentin and pregabalin for chronic neuropathic and early postsurgical pain: current evidence and future directions.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Forecasting; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Pain; Pain, Postoperative; Pregabalin | 2007 |
Non-estrogenic approaches for the treatment of climacteric symptoms.
Topics: Amines; Cyclohexanecarboxylic Acids; Estrogens, Non-Steroidal; Exercise; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Libido; Life Style; Menopause; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Women's Health | 2007 |
Treatment of painful neuropathy.
Topics: Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Peripheral Nervous System Diseases; Pregabalin; Selective Serotonin Reuptake Inhibitors | 2007 |
Restless legs syndrome: nonpharmacologic and pharmacologic treatments.
Topics: Amines; Anemia, Iron-Deficiency; Anticonvulsants; Benzothiazoles; Clonazepam; Cyclohexanecarboxylic Acids; Dopamine Agents; Dopamine Agonists; Ferritins; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Iron; Levodopa; Pramipexole; Restless Legs Syndrome; Trace Elements | 2007 |
Gabapentin.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Tinnitus | 2007 |
Managing neuropathic pain.
Topics: Amines; Analgesics, Opioid; Anticonvulsants; Calcium Channel Blockers; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Disease Progression; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Peripheral Nervous System Diseases; Pregabalin; Receptors, N-Methyl-D-Aspartate; United States | 2007 |
[Therapeutical strategies for essential tremor].
Topics: Adult; Aged; Alprazolam; Amines; Antipsychotic Agents; Botulinum Toxins, Type A; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Deep Brain Stimulation; Essential Tremor; Fructose; Gabapentin; gamma-Aminobutyric Acid; Head Movements; Humans; Middle Aged; Primidone; Propranolol; Severity of Illness Index; Thalamus; Topiramate; Tranquilizing Agents; Voice Disorders | 2007 |
Gabapentin: a multimodal perioperative drug?
Topics: Amines; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Blood Pressure; Chronic Disease; Cyclohexanecarboxylic Acids; Delirium; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Humans; Pain, Postoperative; Postoperative Nausea and Vomiting; Premedication; Randomized Controlled Trials as Topic | 2007 |
The new antiepileptic drugs.
Topics: Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsies, Partial; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Oxcarbazepine; Piracetam; Pregabalin; Topiramate; Triazines; Vigabatrin; Zonisamide | 2007 |
Anticonvulsants for the treatment of behavioral and psychological symptoms of dementia: a literature review.
Topics: Aggression; Amines; Anticonvulsants; Carbamazepine; Cognition Disorders; Cyclohexanecarboxylic Acids; Dementia; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Neuropsychological Tests; Psychomotor Disorders; Triazines; Valproic Acid | 2008 |
[Alpha2-adrenergic receptors in the dorsal horn of the spinal cord--their function and the descending inhibitory systems].
Topics: Acetylcholine; Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics; Animals; Brain-Derived Neurotrophic Factor; Chronic Disease; Clonidine; Cyclohexanecarboxylic Acids; Donepezil; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Neuralgia; Norepinephrine; Piperidines; Posterior Horn Cells; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic | 2007 |
Persistent hiccups during rehabilitation hospitalization: three case reports and review of the literature.
Topics: Aged; Amines; Anti-Anxiety Agents; Anticonvulsants; Cerebral Infarction; Chlorpromazine; Chronic Disease; Contraindications; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Dopamine Agonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hemorrhage; Hiccup; Humans; Length of Stay; Male; Middle Aged; Rehabilitation Centers; Risk Factors; Time Factors | 2007 |
Pain management in the traumatic amputee.
Topics: Acute Disease; Afghanistan; Amines; Amputation, Traumatic; Analgesia; Analgesics; Benchmarking; Causality; Chronic Disease; Complementary Therapies; Critical Care; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Iraq War, 2003-2011; Military Nursing; Military Personnel; Nerve Block; Pain, Postoperative; Phantom Limb; Self Care; Treatment Outcome; United States | 2008 |
[Pathophysiology and treatment of trigeminal autonomic cephalalgias].
Topics: Administration, Oral; Amines; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cluster Headache; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Lamotrigine; Lidocaine; Male; Methysergide; Nociceptors; Oxygen Inhalation Therapy; Paroxysmal Hemicrania; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; SUNCT Syndrome; Topiramate; Triazines; Trigeminal Autonomic Cephalalgias; Trigeminal Nerve; Vasoconstrictor Agents; Vasodilator Agents; Verapamil | 2008 |
Menopause.
Topics: Adult; Aging; Amines; Cyclohexanecarboxylic Acids; Estrogen Replacement Therapy; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Middle Aged; Randomized Controlled Trials as Topic | 2008 |
Use of gabapentin in the treatment of behavioural and psychological symptoms of dementia: a review of the evidence.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amines; Behavior; Cyclohexanecarboxylic Acids; Dementia, Vascular; Gabapentin; gamma-Aminobutyric Acid; Humans; Mental Disorders | 2008 |
[Psychopharmacotherapy in psychiatric comorbidities among patients with chronic pain].
Topics: Amines; Analgesics; Anticonvulsants; Bupropion; Chronic Disease; Cyclohexanecarboxylic Acids; Dopamine Uptake Inhibitors; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Mental Disorders; Pain; Topiramate; Triazines | 2007 |
[Drugs for postoperative analgesia: routine and new aspects: Part 2: opioids, ketamine and gabapentinoids].
Topics: Adjuvants, Pharmaceutic; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Dissociative; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Pain, Postoperative | 2008 |
Are there alternatives to the use of quinine to treat nocturnal leg cramps?
Topics: Amines; Calcium Channel Blockers; Carisoprodol; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Leg; Muscle Cramp; Muscle Relaxants, Central; Orphenadrine; Quinine; Renal Dialysis; Verapamil; Vitamin E | 2008 |
Enriched enrollment: definition and effects of enrichment and dose in trials of pregabalin and gabapentin in neuropathic pain. A systematic review.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic; Treatment Outcome | 2008 |
Treatment of alcohol withdrawal syndrome with carbamazepine, gabapentin, and nitrous oxide.
Topics: Amines; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Ethanol; Gabapentin; gamma-Aminobutyric Acid; Humans; Nitrous Oxide; Substance Withdrawal Syndrome; United States | 2008 |
Acute pain: combination treatments and how we measure their efficacy.
Topics: Acute Disease; Amines; Analgesics, Non-Narcotic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Pain, Postoperative; Perioperative Care; Treatment Outcome | 2008 |
Reporting and analysis of open-label extension studies of anti-epileptic drugs.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Databases, Factual; Drug Resistance; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Levetiracetam; Patient Dropouts; Piracetam; Randomized Controlled Trials as Topic; Research Design; Topiramate | 2008 |
[Chronic intrathecal drug administration for the control of intractable pain].
Topics: Amines; Analgesics, Opioid; Anesthetics, Local; Baclofen; Calcium Channel Blockers; Clonidine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusion Pumps, Implantable; Injections, Spinal; Morphine; Neoplasms; Neuralgia; omega-Conotoxins; Pain, Intractable | 2008 |
Gabapentin: a Ca2+ channel alpha 2-delta ligand far beyond epilepsy therapy.
Topics: Amines; Animals; Anticonvulsants; Calcium Channels, L-Type; Clinical Trials as Topic; Cognition; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Monitoring; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Neuralgia, Postherpetic | 2008 |
Spinal muscular atrophy.
Topics: Action Potentials; Amines; Cyclic AMP Response Element-Binding Protein; Cyclohexanecarboxylic Acids; Electromyography; Gabapentin; gamma-Aminobutyric Acid; Gene Library; Humans; Molecular Biology; Nerve Tissue Proteins; Phenylbutyrates; Randomized Controlled Trials as Topic; RNA-Binding Proteins; Severity of Illness Index; SMN Complex Proteins; Spinal Muscular Atrophies of Childhood; Survival of Motor Neuron 1 Protein | 2008 |
Update on fibromyalgia therapy.
Topics: Amines; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents; Complementary Therapies; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Exercise Therapy; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin | 2008 |
Efficacy of pregabalin and gabapentin for neuropathic pain in spinal-cord injury: an evidence-based evaluation of the literature.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pregabalin; Spinal Cord Injuries | 2008 |
[Pharmacotherapy of central oculomotor disorders].
Topics: 4-Aminopyridine; Amifampridine; Amines; Baclofen; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Memantine; Nystagmus, Pathologic; Vestibular Nuclei | 2008 |
Anticonvulsants to treat idiopathic restless legs syndrome: systematic review.
Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Restless Legs Syndrome; Treatment Outcome; Valproic Acid | 2008 |
Pain relief by gabapentin and pregabalin via supraspinal mechanisms after peripheral nerve injury.
Topics: Amines; Analgesics; Animals; Brain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Neuralgia; Peripheral Nerve Injuries; Pregabalin; Synaptic Transmission | 2008 |
Practical management strategies for the chronic pain patient.
Topics: Administration, Cutaneous; Amines; Analgesics; Antidepressive Agents, Tricyclic; Carbamazepine; Chronic Disease; Clinical Protocols; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Monitoring; Drug Tolerance; Duloxetine Hydrochloride; Family Practice; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Middle Aged; Pain; Practice Guidelines as Topic; Pregabalin; Randomized Controlled Trials as Topic; Substance-Related Disorders; Thiophenes; Treatment Outcome | 2007 |
The complex nature of chronic pelvic pain.
Topics: Adult; Amines; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Chronic Disease; Complementary Therapies; Contraceptives, Oral; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Endometriosis; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Irritable Bowel Syndrome; Mental Disorders; Patient Education as Topic; Pelvic Pain; Psychotherapy; Selective Serotonin Reuptake Inhibitors; Tissue Adhesions; Treatment Outcome | 2007 |
Emergent complications of the newer anticonvulsants.
Topics: Acidosis; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Overdose; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Psychoses, Substance-Induced; Seizures; Tiagabine; Topiramate; Triazines | 2010 |
Anxious to drink: gabapentin normalizes GABAergic transmission in the central amygdala and reduces symptoms of ethanol dependence.
Topics: Alcoholism; Amines; Amygdala; Animals; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans | 2008 |
[Mechanisms of the development of neuropathic pain and its treatment].
Topics: Amines; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Leprosy; Lidocaine; Neuralgia; Posterior Horn Cells; Pregabalin; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers | 2008 |
[Anticonvulsant mood stabilizers in the treatment of behavioral and psychological symptoms of dementia (BPSD)].
Topics: Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dementia; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Psychomotor Agitation; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2008 |
[Central and peripheral mechanisms in antinociception: current and future perspectives].
Topics: Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium Channel Blockers; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Tolerance; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Mexiletine; Nicotinic Agonists; Nociceptors; omega-Conotoxins; Pain; Pyridines; Receptors, Opioid; Sodium Channels | 2008 |
Effectiveness of antiepileptic drugs for the treatment of bipolar disorder: findings from a systematic review.
Topics: Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug-Related Side Effects and Adverse Reactions; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Outcome | 2008 |
Gabapentin in the treatment of mental illness: the echo chamber of the case series.
Topics: Amines; Anticonvulsants; Bipolar Disorder; Conflict of Interest; Cyclohexanecarboxylic Acids; Drug Evaluation; Effect Modifier, Epidemiologic; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Research Design | 2008 |
Menopausal hot flushes revisited.
Topics: Acupuncture Therapy; Adult; Alcohol Drinking; Amines; Caffeine; Cyclohexanecarboxylic Acids; Estrogen Replacement Therapy; Estrogens; Exercise; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Middle Aged; Phytoestrogens; Smoking | 2009 |
Gabapentin versus tricyclic antidepressants for diabetic neuropathy and post-herpetic neuralgia: discrepancies between direct and indirect meta-analyses of randomized controlled trials.
Topics: Amines; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia, Postherpetic; Randomized Controlled Trials as Topic; United States | 2009 |
Use of gabapentin in patients experiencing hot flashes.
Topics: Amines; Breast Neoplasms; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Meta-Analysis as Topic; Randomized Controlled Trials as Topic | 2009 |
Mechanisms of analgesia by gabapentin and pregabalin--calcium channel alpha2-delta [Cavalpha2-delta] ligands.
Topics: Amines; Analgesics; Animals; Calcium Channels; Cell Adhesion; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Biological; Pregabalin; Protein Binding; Protein Transport; Signal Transduction | 2009 |
Drug treatment for spinal muscular atrophy types II and III.
Topics: Amines; Creatine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenylbutyrates; Randomized Controlled Trials as Topic; Spinal Muscular Atrophies of Childhood; Thyrotropin-Releasing Hormone | 2009 |
Meta-analysis of duloxetine vs. pregabalin and gabapentin in the treatment of diabetic peripheral neuropathic pain.
Topics: Amines; Analgesics; Analysis of Variance; Bayes Theorem; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Peripheral Nervous System; Pregabalin; Randomized Controlled Trials as Topic; Thiophenes; Treatment Outcome | 2009 |
Pharmacological treatment for the prevention of delirium: review of current evidence.
Topics: Amines; Anti-Inflammatory Agents; Anticonvulsants; Antipsychotic Agents; Central Nervous System Depressants; Cholinesterase Inhibitors; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Delirium; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives | 2009 |
Pregabalin in the treatment of chronic pain: an overview.
Topics: Amines; Analgesics, Non-Narcotic; Animals; Calcium Channels; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Guidelines as Topic; Humans; Pain; Peripheral Nervous System Diseases; Pregabalin | 2009 |
[Empirical evidence for the use of anticonvulsants in personality disorders].
Topics: Amines; Anticonvulsants; Borderline Personality Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Personality Disorders; Pregabalin; Randomized Controlled Trials as Topic; Topiramate; Triazines; Valproic Acid | 2009 |
Gabapentin for the treatment of hot flashes in women with natural or tamoxifen-induced menopause: a systematic review and meta-analysis.
Topics: Amines; Antineoplastic Agents, Hormonal; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Randomized Controlled Trials as Topic; Tamoxifen | 2009 |
[Antiepileptic drugs for the prevention of pediatric migraine].
Topics: Adolescent; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Tolerance; Fructose; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Levetiracetam; Migraine Disorders; Piracetam; Placebos; Retrospective Studies; Topiramate; Treatment Failure; Valproic Acid | 2009 |
New pharmacotherapies for pediatric seizures.
Topics: Adolescent; Amines; Animals; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Pediatrics; Piracetam; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide | 2004 |
[Nystagmus in ophthalmology].
Topics: Amines; Baclofen; Cyclohexanecarboxylic Acids; Diagnostic Techniques, Ophthalmological; Eye Diseases; Gabapentin; gamma-Aminobutyric Acid; Humans; Nervous System Diseases; Nystagmus, Pathologic; Nystagmus, Physiologic; Ophthalmologic Surgical Procedures | 2009 |
[Update on the treatment of restless legs syndrome].
Topics: Amines; Analgesics, Opioid; Anticonvulsants; Baths; Benzodiazepines; Cyclohexanecarboxylic Acids; Dopamine Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Massage; Periodicity; Restless Legs Syndrome; Severity of Illness Index; Sleep Initiation and Maintenance Disorders | 2009 |
Treatment of fibromyalgia syndrome with gabapentin and pregabalin--a meta-analysis of randomized controlled trials.
Topics: Amines; Analgesics; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Databases, Bibliographic; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Randomized Controlled Trials as Topic; Reproducibility of Results | 2009 |
Gabapentin: a stereochemically constrained gamma amino acid residue in hybrid peptide design.
Topics: Amines; Cyclohexanecarboxylic Acids; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Hydrogen Bonding; Peptides; Protein Conformation; Stereoisomerism | 2009 |
Multimodal analgesia for hip arthroplasty.
Topics: Amines; Analgesia; Analgesics; Anesthetics, Local; Arthroplasty, Replacement, Hip; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Pregabalin | 2009 |
The pharmacological treatment of nystagmus: a review.
Topics: Amines; Animals; Baclofen; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Nystagmus, Congenital; Nystagmus, Pathologic; Randomized Controlled Trials as Topic | 2009 |
Gabapentin and pregabalin for the acute post-operative pain management. A systematic-narrative review of the recent clinical evidences.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain, Postoperative; Pregabalin; Randomized Controlled Trials as Topic | 2009 |
Fibromyalgia and headache disorders.
Topics: Amines; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders; Humans; Meta-Analysis as Topic; Pregabalin; Randomized Controlled Trials as Topic | 2009 |
[Anticonvulsant hypersensitivity syndrome: an entity to be remembered].
Topics: Adolescent; Amines; Anemia, Hemolytic; Anticonvulsants; Astrocytoma; Brain Neoplasms; Carbamazepine; Chemical and Drug Induced Liver Injury; Cyclohexanecarboxylic Acids; Diagnostic Errors; Drug Eruptions; Drug Therapy, Combination; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Female; Gabapentin; gamma-Aminobutyric Acid; Ganglioneuroma; Humans; Lymphatic Diseases; Parahippocampal Gyrus; Phenytoin; Radiosurgery | 2009 |
Treatment of neuropathic pain: an overview of recent guidelines.
Topics: Amines; Analgesics; Analgesics, Opioid; Anesthetics, Local; Antidepressive Agents; Canada; Cyclohexanecarboxylic Acids; Europe; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; International Cooperation; Lidocaine; Neuralgia; Practice Guidelines as Topic; Pregabalin; Selective Serotonin Reuptake Inhibitors; Societies, Medical; Tramadol | 2009 |
[Use of antiepileptic drugs for the preventive treatment of migraine].
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Humans; Ion Channels; Migraine Disorders; Premedication; Synaptic Transmission; Topiramate; Valproic Acid | 2009 |
[Pain relief by gabapentin via supraspinal mechanisms in neuropathic conditions].
Topics: Amines; Analgesics; Animals; Brain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Pain; Peripheral Nervous System Diseases | 2009 |
Is anticonvulsant treatment of mania a class effect? Data from randomized clinical trials.
Topics: Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium Compounds; Oxcarbazepine; Randomized Controlled Trials as Topic; Topiramate; Triazines; Valproic Acid | 2011 |
What can be done about hot flushes after treatment for breast cancer?
Topics: Amines; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Clonidine; Complementary Therapies; Cyclohexanecarboxylic Acids; Drugs, Chinese Herbal; Estrogen Replacement Therapy; Estrogens; Exercise; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Middle Aged; Norepinephrine; Progesterone; Quality of Life; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Stellate Ganglion; Survivors | 2010 |
Focus on therapy of primary stabbing headache.
Topics: Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders, Primary; Humans; Indomethacin; Melatonin; Ophthalmic Nerve; Treatment Outcome | 2010 |
New treatments for chronic prostatitis/chronic pelvic pain syndrome.
Topics: Amines; Chronic Disease; Cognitive Behavioral Therapy; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pelvic Pain; Prostatitis; Randomized Controlled Trials as Topic; Treatment Outcome | 2010 |
Evidence for sensory neuropathy and pharmacologic management.
Topics: Adrenergic Uptake Inhibitors; Amines; Amitriptyline; Anticonvulsants; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Vagus Nerve Diseases; Virus Diseases | 2010 |
Focus on therapy: hemicrania continua and new daily persistent headache.
Topics: Amines; Analgesics; Celecoxib; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Headache; Headache Disorders; Humans; Indomethacin; Pyrazoles; Sulfonamides; Topiramate; Treatment Outcome | 2010 |
Behavioral and cognitive effects of anti-epileptic drugs.
Topics: Amines; Anticonvulsants; Antidepressive Agents; Behavior; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Lamotrigine; Neurotransmitter Agents; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Triazines; Vigabatrin | 2010 |
Recommendations for the pharmacological management of neuropathic pain: an overview and literature update.
Topics: Acetamides; Amines; Analgesics; Analgesics, Opioid; Anesthetics, Local; Antidepressive Agents; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Lacosamide; Neuralgia; Practice Guidelines as Topic; Pregabalin; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors | 2010 |
The anti-allodynic alpha(2)delta ligand pregabalin inhibits the trafficking of the calcium channel alpha(2)delta-1 subunit to presynaptic terminals in vivo.
Topics: Amines; Analgesics; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Models, Biological; Neuralgia; Pregabalin; Presynaptic Terminals; Protein Transport | 2010 |
EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision.
Topics: Amines; Analgesia; Analgesics; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Europe; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Outcome Assessment, Health Care; Peripheral Nervous System Diseases; Randomized Controlled Trials as Topic; Treatment Outcome | 2010 |
Lumbar spinal stenosis: a brief review of the nonsurgical management.
Topics: Administration, Intranasal; Alprostadil; Amines; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents; Calcitonin; Cyclohexanecarboxylic Acids; Epidural Space; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Pain; Randomized Controlled Trials as Topic; Research Design; Spinal Stenosis; Vitamin B 12 | 2010 |
Single dose oral gabapentin for established acute postoperative pain in adults.
Topics: Acute Disease; Administration, Oral; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Randomized Controlled Trials as Topic | 2010 |
Central sensitization and Ca(V)α₂δ ligands in chronic pain syndromes: pathologic processes and pharmacologic effect.
Topics: Amines; Analgesics; Animals; Calcium Channels; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Neuronal Plasticity; Pain; Pregabalin | 2010 |
Psychiatric concerns in pediatric epilepsy.
Topics: Adolescent; Amines; Anxiety Disorders; Bipolar Disorder; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Cyclohexanols; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Mental Disorders; Norepinephrine; Pregabalin; Selective Serotonin Reuptake Inhibitors; Valproic Acid; Venlafaxine Hydrochloride; Young Adult | 2010 |
Tremors: learning to stop the shakes.
Topics: Adrenergic beta-Antagonists; Alprazolam; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Learning; Propranolol; Self Efficacy; Theophylline; Tremor; Vasodilator Agents | 2010 |
Gabapentin for the treatment of cancer-related pain syndromes.
Topics: Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neoplasms; Pain; Pain Measurement; Peripheral Nervous System Diseases; Syndrome; Treatment Outcome | 2010 |
An algorithm for the treatment of chronic testicular pain.
Topics: Algorithms; Amines; Analgesics; Anesthetics; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Chronic Disease; Cyclohexanecarboxylic Acids; Denervation; Gabapentin; gamma-Aminobutyric Acid; Genital Diseases, Male; Humans; Injections; Male; Nerve Block; Orchiectomy; Pain; Pain Management; Physical Examination; Posture; Scrotum; Spermatic Cord; Testis; Ultrasonography; Vasectomy | 2010 |
Oxycodone combinations for pain relief.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; Oxycodone; Pain; Pregabalin | 2010 |
The alpha2-delta protein: an auxiliary subunit of voltage-dependent calcium channels as a recognized drug target.
Topics: Amines; Animals; Brain; Calcium Channel Blockers; Calcium Channels; Cyclohexanecarboxylic Acids; Drug Delivery Systems; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; Genomics; Humans; Models, Biological; Pregabalin; Protein Subunits | 2010 |
[Is postoperative pain only a nociceptive pain?].
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Nociceptors; Pain, Postoperative; Pregabalin; Treatment Outcome | 2010 |
Hot flushes: are there effective alternatives to estrogen?
Topics: Acupuncture Therapy; Amines; Cimicifuga; Clonidine; Cyclohexanecarboxylic Acids; Estrogen Replacement Therapy; Exercise; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; New Zealand; Norpregnenes; Phytoestrogens; Progesterone; Selective Serotonin Reuptake Inhibitors; Skin; United Kingdom; United States; Vitamin E | 2010 |
A comparison of the pharmacokinetics and pharmacodynamics of pregabalin and gabapentin.
Topics: Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Pregabalin | 2010 |
Non-hormonal interventions for hot flushes in women with a history of breast cancer.
Topics: Acupuncture Therapy; Amines; Breast Neoplasms; Clonidine; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Homeopathy; Hot Flashes; Humans; Magnetic Field Therapy; Norepinephrine; Randomized Controlled Trials as Topic; Relaxation Therapy; Serotonin Antagonists; Vitamin E; Vitamins | 2010 |
[IGOST guideline for pharmacotherapy of low back pain].
Topics: Amines; Aminopyridines; Analgesics; Analgesics, Opioid; Anti-Anxiety Agents; Antidepressive Agents; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Methocarbamol; Muscle Relaxants, Central; Neuromuscular Agents; Osteoporosis; Practice Guidelines as Topic; Tolperisone | 2010 |
Investigational agents for the irritable bowel syndrome.
Topics: Amines; Cyclohexanecarboxylic Acids; Drugs, Investigational; Female; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Agents; Humans; Irritable Bowel Syndrome; Male; Melatonin; Molecular Targeted Therapy; Narcotic Antagonists; Nerve Growth Factors; Neurotransmitter Agents; Randomized Controlled Trials as Topic; Receptors, Cholecystokinin; Receptors, Corticotropin-Releasing Hormone; Receptors, Guanylate Cyclase-Coupled; Receptors, Opioid | 2010 |
Vasomotor symptoms: viewpoint from the Indian subcontinent and management of a common menopausal problem.
Topics: Aging; Amines; Antihypertensive Agents; Asian People; Complementary Therapies; Cyclohexanecarboxylic Acids; Estrogen Receptor beta; Estrogen Receptor Modulators; Estrogen Replacement Therapy; Female; Gabapentin; gamma-Aminobutyric Acid; Hormone Replacement Therapy; Hot Flashes; Humans; India; Life Style; Menopause; Mind-Body Therapies; Nonprescription Drugs; Phytoestrogens; Prevalence; Progesterone; Vasomotor System | 2010 |
Spasticity: revisiting the role and the individual value of several pharmacological treatments.
Topics: Amines; Baclofen; Botulinum Toxins; Calcium Channel Blockers; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Diazepam; Gabapentin; gamma-Aminobutyric Acid; Humans; Muscle Relaxants, Central; Muscle Spasticity; Recovery of Function; Treatment Outcome | 2010 |
Pharmacologic treatment for low back pain: one component of pain care.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Neuromuscular Agents | 2010 |
5% lidocaine-medicated plaster vs other relevant interventions and placebo for post-herpetic neuralgia (PHN): a systematic review.
Topics: Administration, Cutaneous; Amines; Analgesics; Anesthetics, Local; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Neuralgia, Postherpetic; Treatment Outcome | 2011 |
Pregabalin versus gabapentin in partial epilepsy: a meta-analysis of dose-response relationships.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Randomized Controlled Trials as Topic | 2010 |
Gabapentin and pregabalin in the treatment of fibromyalgia: a systematic review and a meta-analysis.
Topics: Amines; Analgesics, Non-Narcotic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Outcome Assessment, Health Care; Pain; Pregabalin; Randomized Controlled Trials as Topic; Treatment Outcome | 2010 |
Systematic review of the comparative effectiveness of antiepileptic drugs for fibromyalgia.
Topics: Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin | 2011 |
[Development of animal models of herpetic pain and postherpetic neuralgia and elucidation of the mechanisms of the onset and inhibition of allodynia].
Topics: Amines; Analgesics; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Cyclooxygenase Inhibitors; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Hyperalgesia; Mice; Neuralgia, Postherpetic; Nitric Oxide; Nitric Oxide Synthase; Pain; Prostaglandins; Receptors, Opioid; Risk Factors | 2011 |
Use of gabapentin for the management of natural or surgical menopausal hot flashes.
Topics: Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Postmenopause; Randomized Controlled Trials as Topic; Uterine Diseases | 2011 |
Cost-effectiveness analysis of a new 8% capsaicin patch compared to existing therapies for postherpetic neuralgia.
Topics: Administration, Topical; Amines; Anesthetics, Local; Antidepressive Agents, Tricyclic; Capsaicin; Clinical Trials as Topic; Costs and Cost Analysis; Cyclohexanecarboxylic Acids; Dopamine Uptake Inhibitors; Duloxetine Hydrochloride; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Male; Markov Chains; Neuralgia, Postherpetic; Pregabalin; Quality of Life; Sensory System Agents; Thiophenes; Transdermal Patch | 2011 |
Gabapentin for chronic neuropathic pain and fibromyalgia in adults.
Topics: Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Randomized Controlled Trials as Topic | 2011 |
Conformationally restricted GABA analogs: from rigid carbocycles to cage hydrocarbons.
Topics: Adamantane; Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrocarbons, Cyclic; Molecular Conformation; Structure-Activity Relationship | 2011 |
[Efficacy of new antiepileptic drugs and the next generation drugs].
Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Approval; Drug Design; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Induced Pluripotent Stem Cells; Lamotrigine; Levetiracetam; Piracetam; Topiramate; Triazines | 2011 |
Are antiepileptic drugs used in the treatment of migraine associated with an increased risk of suicidality?
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Labeling; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders; Risk Factors; Suicidal Ideation; Suicide; Topiramate; Treatment Outcome; United States; United States Food and Drug Administration; Valproic Acid | 2011 |
The efficacy of anticonvulsants on orofacial pain: a systematic review.
Topics: Amines; Anticonvulsants; Burning Mouth Syndrome; Carbamazepine; Clonazepam; Cyclohexanecarboxylic Acids; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Masticatory Muscles; Pimozide; Randomized Controlled Trials as Topic; Tocainide; Triazines; Trigeminal Neuralgia | 2011 |
[Japanese SUNCT patient responsive to gabapentin].
Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; SUNCT Syndrome; Treatment Outcome | 2011 |
Complex regional pain syndrome.
Topics: Amines; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Autonomic Nerve Block; Causalgia; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Diphosphonates; Electromyography; Free Radical Scavengers; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Humans; Osteoporosis; Physical Therapy Modalities; Skin; Thermography; Treatment Outcome | 2011 |
[Neuropathic pain in oncology. Novel evidence for clinical practice].
Topics: Amines; Amitriptyline; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Neoplasms; Neuralgia; Pregabalin; Tramadol; Treatment Outcome | 2011 |
[Pregabalin and gabapentin in multiple sclerosis: clinical experiences and therapeutic implications].
Topics: Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Antineoplastic Agents; Carbamazepine; Cohort Studies; Cyclohexanecarboxylic Acids; Disability Evaluation; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Male; Middle Aged; Mitoxantrone; Multiple Sclerosis; Neurologic Examination; Pregabalin; Retrospective Studies; Triazines; Valproic Acid; Young Adult | 2011 |
[Molecular mechanisms and clinical pharmacology of chronic pain].
Topics: Amines; Animals; Anterior Horn Cells; Antidepressive Agents; Brain; Chronic Disease; Cyclohexanecarboxylic Acids; Emotions; Gabapentin; gamma-Aminobutyric Acid; Humans; Inflammation Mediators; Neurons, Afferent; Pain; Peripheral Nerves; Receptors, N-Methyl-D-Aspartate; TRPV Cation Channels | 2010 |
[Some adjuvants added to local anesthetics improve the duration and quality of epidural anesthesia].
Topics: Adjuvants, Anesthesia; Amines; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Buprenorphine; Clonidine; Cyclohexanecarboxylic Acids; Dexmedetomidine; Droperidol; Drug Compounding; Epinephrine; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Magnesium Sulfate; Midazolam; Morphine; Neostigmine | 2010 |
[Future neuroprotective strategies in the post-thrombolysis era--neurovascular unit protection and vascular endothelial protection].
Topics: Amines; Animals; Antipyrine; Cerebral Infarction; Cyclohexanecarboxylic Acids; Edaravone; Endothelium, Vascular; Free Radical Scavengers; Gabapentin; gamma-Aminobutyric Acid; Humans; Thrombolytic Therapy; Tissue Plasminogen Activator | 2011 |
Clinical comparability of the new antiepileptic drugs in refractory partial epilepsy: a systematic review and meta-analysis.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Levetiracetam; Nipecotic Acids; Piracetam; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Treatment Outcome | 2011 |
Anticonvulsants for tinnitus.
Topics: Administration, Oral; Amines; Anticonvulsants; Carbamazepine; Chronic Disease; Cyclohexanecarboxylic Acids; Flunarizine; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Tinnitus; Triazines | 2011 |
Gabapentin reduces experimental secondary neurologic dysfunction in rats.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Nervous System Diseases; Rats; Spasm; Spinal Cord Injuries; Thoracic Vertebrae | 2011 |
Drug therapy for treating post-dural puncture headache.
Topics: Adrenocorticotropic Hormone; Amines; Analgesics; Caffeine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocortisone; Male; Pain Measurement; Post-Dural Puncture Headache; Randomized Controlled Trials as Topic; Spinal Puncture; Sumatriptan; Theophylline; Treatment Outcome | 2011 |
Review of current guidelines on the care of postherpetic neuralgia.
Topics: Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Capsaicin; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Neuralgia, Postherpetic; Practice Guidelines as Topic; Pregabalin; Primary Health Care; Tramadol; Transdermal Patch | 2011 |
Gabapentin for tinnitus: a systematic review.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hearing Loss; Humans; Randomized Controlled Trials as Topic; Tinnitus; Treatment Failure | 2011 |
Extended-release gabapentin in post-herpetic neuralgia.
Topics: Amines; Analgesics, Non-Narcotic; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia, Postherpetic | 2011 |
Perimenopausal migraine in women with vasomotor symptoms.
Topics: Amines; Cyclohexanecarboxylic Acids; Estrogen Replacement Therapy; Estrogens; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Migraine Disorders; Neurotransmitter Agents; Perimenopause | 2012 |
Non-estrogen conventional and phytochemical treatments for vasomotor symptoms: what needs to be known for practice.
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Anticonvulsants; Cimicifuga; Clonidine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Phytoestrogens; Phytotherapy; Plant Extracts; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sweating; Vasomotor System | 2012 |
Pharmacologic prophylaxis for acute mountain sickness: a systematic shortcut review.
Topics: Acetazolamide; Altitude Sickness; Amines; Carbonic Anhydrase Inhibitors; Cyclohexanecarboxylic Acids; Dexamethasone; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Humans; Sumatriptan | 2012 |
Drug treatment for spinal muscular atrophy types II and III.
Topics: Acetylcarnitine; Adolescent; Amines; Child; Child, Preschool; Creatine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydroxyurea; Neuroprotective Agents; Phenylbutyrates; Randomized Controlled Trials as Topic; Spinal Muscular Atrophies of Childhood; Thyrotropin-Releasing Hormone; Valproic Acid | 2011 |
[Prevention of postoperative hyperalgesia].
Topics: Amantadine; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Ketamine; Magnesium Compounds; Pain Management; Pain, Postoperative; Receptors, N-Methyl-D-Aspartate; Risk Assessment | 2012 |
Post burn pruritus--a review of current treatment options.
Topics: Amines; Analgesics; Burns; Cyclohexanecarboxylic Acids; Emollients; Gabapentin; gamma-Aminobutyric Acid; Histamine Antagonists; Humans; Nerve Fibers, Unmyelinated; Pruritus | 2012 |
Androgen deprivation therapy-associated vasomotor symptoms.
Topics: Amines; Androgen Antagonists; Anticonvulsants; Antidepressive Agents; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Male; Pregabalin; Prostatic Neoplasms; Vasomotor System | 2012 |
Acute renal failure due to gabapentin. A case report and literature.
Topics: Acute Kidney Injury; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2012 |
Non-opioid IV adjuvants in the perioperative period: pharmacological and clinical aspects of ketamine and gabapentinoids.
Topics: Adjuvants, Pharmaceutic; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Pain, Postoperative; Perioperative Period; Pregabalin | 2012 |
Effective and clinically meaningful non-hormonal hot flash therapies.
Topics: Actaea; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Cyclohexanols; Desvenlafaxine Succinate; Estrogen Replacement Therapy; Female; Gabapentin; gamma-Aminobutyric Acid; Glycine max; Hot Flashes; Humans; Isoflavones; Mandelic Acids; Menopause; Phytotherapy; Plant Extracts | 2012 |
The prevention of chronic postsurgical pain using gabapentin and pregabalin: a combined systematic review and meta-analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Evidence-Based Medicine; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Male; Middle Aged; Odds Ratio; Pain Measurement; Pain, Postoperative; Perioperative Period; Pregabalin; Time Factors; Treatment Outcome; Young Adult | 2012 |
Single dose of gabapentin for prophylaxis intrathecal morphine-induced pruritus in orthopedic surgery: a randomized controlled trial.
Topics: Adolescent; Adult; Aged; Amines; Analgesics, Opioid; Anesthesia, Spinal; Antipruritics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Male; Middle Aged; Morphine; Orthopedic Procedures; Postoperative Period; Prospective Studies; Pruritus; Young Adult | 2012 |
[Mechanisms of action of therapeutic agents in the treatment of chronic pain in the spinal cord].
Topics: Amines; Antidepressive Agents; Calcium Channel Blockers; Chronic Pain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Pregabalin; Receptors, Opioid, mu; Selective Serotonin Reuptake Inhibitors; Spinal Cord; Tramadol | 2011 |
Drug treatment for spinal muscular atrophy types II and III.
Topics: Acetylcarnitine; Adolescent; Amines; Child; Child, Preschool; Creatine; Cyclohexanecarboxylic Acids; Disease Progression; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydroxyurea; Neuroprotective Agents; Phenylbutyrates; Randomized Controlled Trials as Topic; Spinal Muscular Atrophies of Childhood; Thyrotropin-Releasing Hormone; Valproic Acid | 2012 |
Gabapentin for pruritus in palliative care.
Topics: Amines; Analgesics, Opioid; Burns; Cholestasis; Cyclohexanecarboxylic Acids; Dermatologic Agents; Gabapentin; gamma-Aminobutyric Acid; Humans; Neoplasms; Palliative Care; Pruritus | 2013 |
The pharmacological treatment of acquired nystagmus.
Topics: Amines; Aminopyridines; Baclofen; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Nystagmus, Congenital; Nystagmus, Pathologic; Randomized Controlled Trials as Topic; Treatment Outcome | 2012 |
[Pharmacological treatment of spasticity in multiple sclerosis].
Topics: Algorithms; Amines; Baclofen; Botulinum Toxins, Type A; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Double-Blind Method; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusion Pumps, Implantable; Injections, Spinal; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Nerve Block; Neuromuscular Agents; Randomized Controlled Trials as Topic; Spasm; Vigabatrin | 2012 |
Use of gabapentin and pregabalin for hand surgery patients.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hand; Humans; Neuralgia; Pain, Postoperative; Pregabalin | 2012 |
Combination pharmacotherapy for the treatment of neuropathic pain in adults.
Topics: Acetaminophen; Adult; Amines; Analgesics; Antidepressive Agents, Tricyclic; Benzodiazepinones; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; N-Methylaspartate; Neuralgia; Nortriptyline; Phenylurea Compounds; Pregabalin; Thioctic Acid; Tramadol | 2012 |
ADMET considerations for restless leg syndrome drug treatments.
Topics: Amines; Anticonvulsants; Benzothiazoles; Carbamates; Cyclohexanecarboxylic Acids; Dopamine Agents; Dopamine Agonists; Ergolines; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Levodopa; Neuralgia; Pramipexole; Pregabalin; Randomized Controlled Trials as Topic; Restless Legs Syndrome; Tetrahydronaphthalenes; Thiophenes; Treatment Outcome | 2012 |
New generation nonhormonal management for hot flashes.
Topics: Amines; Anticonvulsants; Citalopram; Cyclohexanecarboxylic Acids; Estrogen Replacement Therapy; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Pregabalin; Selective Serotonin Reuptake Inhibitors | 2013 |
Clinical development of a once-daily gastroretentive formulation of gabapentin for treatment of postherpetic neuralgia: an overview.
Topics: Amines; Analgesics; Biological Availability; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Gabapentin; gamma-Aminobutyric Acid; Humans; Intestinal Absorption; Neuralgia, Postherpetic; Tablets | 2012 |
Gabapentin for once-daily treatment of post-herpetic neuralgia: a review.
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia, Postherpetic; Randomized Controlled Trials as Topic | 2012 |
The intestinal absorption mechanism of gabapentin makes it appropriate for gastroretentive delivery.
Topics: Amines; Analgesics; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Intestinal Absorption; Neuralgia, Postherpetic; Solubility | 2013 |
Chronic pain perspectives: Treating herpes zoster and postherpetic neuralgia: an evidence-based approach.
Topics: Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Antipruritics; Capsaicin; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia, Postherpetic | 2012 |
[Burning sensation in oral cavity--burning mouth syndrome in everyday medical practice].
Topics: Acetamides; Amines; Anti-Anxiety Agents; Antidepressive Agents; Antioxidants; Burning Mouth Syndrome; Chlordiazepoxide; Clonazepam; Cognitive Behavioral Therapy; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Histamine H2 Antagonists; Humans; Male; Paresthesia; Peripheral Nervous System Diseases; Phantom Limb; Piperidines; Prognosis; Pyridines; Sex Factors; Thioctic Acid; Tongue; Xerostomia | 2012 |
Efficacy of gabapentin for treatment of adults with phantom limb pain.
Topics: Administration, Oral; Adult; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Phantom Limb; Randomized Controlled Trials as Topic; Treatment Outcome | 2012 |
Clinical inquiry: what medications are best for diabetic neuropathic pain?
Topics: Amines; Analgesics; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Practice Guidelines as Topic; Thiophenes | 2012 |
Use of specific neuromodulators in the treatment of chronic, idiopathic cough: a systematic review.
Topics: Amines; Amitriptyline; Baclofen; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents; Pregabalin; Quality of Life | 2013 |
Clinical Inquiry: Do venlafaxine and gabapentin control hot flashes in women with a history of breast cancer?
Topics: Amines; Anti-Anxiety Agents; Breast Neoplasms; Constipation; Cyclohexanecarboxylic Acids; Cyclohexanols; Dizziness; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Off-Label Use; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Treatment Outcome; Venlafaxine Hydrochloride | 2012 |
Understanding the pharmacokinetics of anxiolytic drugs.
Topics: Adrenergic beta-Antagonists; Amines; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Atenolol; Benzodiazepines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Histamine Antagonists; Humans; Hydroxyzine; Pregabalin; Propranolol; Sleep Initiation and Maintenance Disorders | 2013 |
Pharmacokinetics, efficacy, and tolerability of a once-daily gastroretentive dosage form of gabapentin for the treatment of postherpetic neuralgia.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Tract; Humans; Neuralgia, Postherpetic; Tablets | 2013 |
Implications and mechanism of action of gabapentin in neuropathic pain.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain Measurement; Spinal Cord | 2013 |
A review of analgesic compounds used in food animals in the United States.
Topics: Adrenergic alpha-Agonists; Amines; Analgesia; Analgesics; Analgesics, Opioid; Anesthetics, Local; Animal Husbandry; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Meat; Off-Label Use; Pain; Receptors, N-Methyl-D-Aspartate; United States | 2013 |
Clinical Reasoning: a 57-year-old man with jaw spasms.
Topics: Adrenergic Uptake Inhibitors; Amines; Anticonvulsants; Brain Neoplasms; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Facial Muscles; Gabapentin; gamma-Aminobutyric Acid; Hemangioma; Humans; Jaw; Male; Middle Aged; Spasm; Thiophenes | 2013 |
Chronic pain after childbirth.
Topics: Acute Pain; Adrenergic alpha-Agonists; Adult; Amines; Analgesics; Anesthetics, Dissociative; Cesarean Section; Chronic Pain; Clonidine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Ketamine; Magnesium Sulfate; Nerve Block; Oxytocin; Pain, Postoperative; Parturition; Pelvic Pain; Peritoneum; Pregabalin; Pregnancy; Risk Factors; Uterus | 2013 |
Restless legs syndrome: pathophysiology and modern management.
Topics: Amines; Anemia; Anticonvulsants; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dopamine Agonists; Female; Gabapentin; gamma-Aminobutyric Acid; Genetic Linkage; Humans; Intracellular Signaling Peptides and Proteins; Male; Neuropeptides; Orexins; Paresthesia; Pregnancy; Pregnancy Complications; Prevalence; Quality of Life; Restless Legs Syndrome | 2013 |
Clinical practice. Chronic pruritus.
Topics: Amines; Antidepressive Agents, Tricyclic; Behavior Therapy; Chronic Disease; Cyclohexanecarboxylic Acids; Emollients; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Histamine Antagonists; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Pruritus | 2013 |
Nummular headache update.
Topics: Age Distribution; Amines; Analgesics; Anti-Dyskinesia Agents; Antidepressive Agents, Tricyclic; Botulinum Toxins; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders, Primary; Humans; Male; Pain Measurement; Sensation Disorders; Sex Distribution | 2013 |
Gabapentin therapy of hiccups.
Topics: Amines; Animals; Anti-Anxiety Agents; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans | 2013 |
A systematic review of the utility of anticonvulsant pharmacotherapy in the treatment of vulvodynia pain.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Substance Withdrawal Syndrome; Vulvodynia | 2013 |
Meta-analyses of dose-exposure relationships for gabapentin following oral administration of gabapentin and gabapentin enacarbil.
Topics: Administration, Oral; Amines; Biological Availability; Carbamates; Computer Simulation; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Biological; Prodrugs | 2013 |
Prurigo nodularis: an update on etiopathogenesis and therapy.
Topics: Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Dermatologic Agents; Epidermis; Female; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Physical Therapy Modalities; Pregabalin; Prurigo; Sex Factors; Skin | 2013 |
Gabapentin or pregabalin for the prophylaxis of episodic migraine in adults.
Topics: Adult; Amines; Anticonvulsants; Carbamates; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders; Pregabalin; Randomized Controlled Trials as Topic | 2013 |
Is there a role for gabapentin in preventing or treating pain following thoracic surgery?
Topics: Administration, Oral; Amines; Analgesics; Benchmarking; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Thoracotomy; Treatment Outcome | 2013 |
Non-hormonal management of vasomotor symptoms.
Topics: Amines; Anticonvulsants; Clonidine; Complementary Therapies; Cyclohexanecarboxylic Acids; Estrogen Replacement Therapy; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Nonprescription Drugs; Receptors, Adrenergic, alpha; Selective Serotonin Reuptake Inhibitors; Serotonin; Women's Health | 2013 |
Pharmacotherapy for the prevention of chronic pain after surgery in adults.
Topics: Adrenal Cortex Hormones; Adult; Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ibuprofen; Ketamine; Male; Mexiletine; Pain, Postoperative; Pregabalin; Randomized Controlled Trials as Topic | 2013 |
Update on neuropathic pain treatment: ion channel blockers and gabapentinoids.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Neuralgia | 2013 |
Gabapentin add-on for drug-resistant partial epilepsy.
Topics: Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Failure | 2013 |
Management of chronic pain following nerve injuries/CRPS type II.
Topics: Amines; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Capsaicin; Causalgia; Chronic Pain; Cyclohexanecarboxylic Acids; Diphosphonates; Gabapentin; gamma-Aminobutyric Acid; Humans; Nerve Block; Peripheral Nerve Injuries; Sensory System Agents; Terminology as Topic | 2013 |
Therapeutic options for the treatment of postherpetic neuralgia: a systematic review.
Topics: Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Approval; Gabapentin; gamma-Aminobutyric Acid; Humans; Medication Adherence; Neuralgia, Postherpetic; Off-Label Use; Pregabalin; Quality of Life; United States; United States Food and Drug Administration | 2013 |
Gabapentin and pregabalin in the management of postoperative pain after lumbar spinal surgery: a systematic review and meta-analysis.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lumbar Vertebrae; Pain, Postoperative; Pregabalin; Randomized Controlled Trials as Topic; Treatment Outcome | 2013 |
Evidence-based guidance for the management of postherpetic neuralgia in primary care.
Topics: Amines; Analgesics; Capsaicin; Carbamates; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia, Postherpetic; Practice Guidelines as Topic; Pregabalin; Primary Health Care | 2013 |
Sensory symptoms in restless legs syndrome: the enigma of pain.
Topics: Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Restless Legs Syndrome; Sleep Wake Disorders | 2013 |
The efficacy of nonestrogenic therapy to hot flashes in cancer patients under hormone manipulation therapy: a systematic review and meta-analysis.
Topics: Amines; Antineoplastic Agents, Hormonal; Cyclohexanecarboxylic Acids; Cyclohexanols; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Neoplasms, Hormone-Dependent; Randomized Controlled Trials as Topic; Treatment Outcome; Venlafaxine Hydrochloride | 2013 |
Gabapentin withdrawal: case report in an older adult and review of the literature.
Topics: Aged; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Depression; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Withholding Treatment | 2013 |
Vestibular paroxysmia associated with paroxysmal pulsatile tinnitus: a case report and review of the literature.
Topics: Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Male; Nerve Compression Syndromes; Tinnitus; Vertigo | 2013 |
Perioperative gabapentinoids: choice of agent, dose, timing, and effects on chronic postsurgical pain.
Topics: Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Perioperative Care; Pregabalin | 2013 |
The usual treatment of trigeminal autonomic cephalalgias.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Sumatriptan; SUNCT Syndrome; Topiramate; Treatment Outcome; Trigeminal Autonomic Cephalalgias | 2013 |
Asterixis related to gabapentin intake: a case report and review.
Topics: Aged; Amines; Cyclohexanecarboxylic Acids; Dyskinesias; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypesthesia; Male; Neurotoxicity Syndromes; Polyneuropathies | 2013 |
Anticonvulsants for fibromyalgia.
Topics: Acetamides; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Lacosamide; Levetiracetam; Piracetam; Pregabalin | 2013 |
Pharmacological treatment for pain in Guillain-Barré syndrome.
Topics: Amines; Analgesics; Carbamazepine; Constipation; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Humans; Immunoglobulins, Intravenous; Methylprednisolone; Nausea; Pain; Pain Measurement; Randomized Controlled Trials as Topic | 2013 |
The treatment of tremor.
Topics: Amines; Anticonvulsants; Botulinum Toxins; Cyclohexanecarboxylic Acids; Deep Brain Stimulation; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Topiramate; Tremor | 2014 |
Post-surgical pain syndromes: a review for the non-pain specialist.
Topics: Age Factors; Amines; Analgesics; Anesthesia; Anesthetics; Anesthetics, Local; Animals; Chronic Pain; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain, Postoperative; Risk Factors; Sex Factors; Syndrome | 2014 |
Antiepileptic drugs for neuropathic pain and fibromyalgia - an overview of Cochrane reviews.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Intention to Treat Analysis; Neuralgia; Pain Measurement; Patient Dropouts; Pregabalin; Review Literature as Topic | 2013 |
Recent advances in sleep research.
Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Amines; Antiparkinson Agents; Biomedical Research; Cyclohexanecarboxylic Acids; Databases, Factual; Europe; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Male; Mandibular Advancement; Mental Disorders; Middle Aged; Polysomnography; Psychometrics; Restless Legs Syndrome; Sex Distribution; Sleep Apnea Syndromes; Sleep Bruxism; Sleep Medicine Specialty; Sleep Wake Disorders; Snoring; Young Adult | 2013 |
Efficacy and safety of gabapentin for treatment of postherpetic neuralgia: a meta-analysis of randomized controlled trials.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia, Postherpetic; Randomized Controlled Trials as Topic | 2014 |
Beyond neuropathic pain: gabapentin use in cancer pain and perioperative pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neoplasms; Pain; Perioperative Period | 2014 |
Anticonvulsant medication use for the management of pain following spinal cord injury: systematic review and effectiveness analysis.
Topics: Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain Management; Pregabalin; Randomized Controlled Trials as Topic; Spinal Cord Injuries | 2014 |
['Postoperative pain treatment' practice guideline revised].
Topics: Adult; Amines; Analgesia, Epidural; Child; Cyclohexanecarboxylic Acids; Dexamethasone; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Netherlands; Pain, Postoperative; Postoperative Nausea and Vomiting; Practice Guidelines as Topic; Pregabalin | 2013 |
[Pain management in patients with liver cirrhosis].
Topics: Acetaminophen; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Hepatorenal Syndrome; Humans; Inactivation, Metabolic; Liver; Liver Cirrhosis; Narcotics; Nerve Block; Pain Management; Physical Therapy Modalities; Practice Guidelines as Topic; Pregabalin | 2014 |
Treatment of hidradenitis supprurativa associated pain with nonsteroidal anti-inflammatory drugs, acetaminophen, celecoxib, gabapentin, pegabalin, duloxetine, and venlafaxine.
Topics: Acetaminophen; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclohexanecarboxylic Acids; Cyclohexanols; Drug Therapy, Combination; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hidradenitis Suppurativa; Humans; Pain; Pain Management; Pregabalin; Pyrazoles; Selective Serotonin Reuptake Inhibitors; Sulfonamides; Thiophenes; Venlafaxine Hydrochloride | 2013 |
Uremic pruritus.
Topics: Acupuncture Therapy; Amines; Anti-Inflammatory Agents; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; gamma-Linolenic Acid; Humans; Morphinans; Naltrexone; Narcotic Antagonists; Pentoxifylline; Phototherapy; Pregabalin; Pruritus; Receptors, Opioid, kappa; Renal Insufficiency, Chronic; Spiro Compounds; Tacrolimus; Thalidomide; Uremia | 2015 |
Managing difficult pain conditions in the cancer patient.
Topics: Amines; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Breakthrough Pain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Male; Neoplasms; Neuralgia; Pain, Intractable; Practice Guidelines as Topic | 2014 |
Analgesia for the cirrhotic patient: a literature review and recommendations.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Contraindications; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Laxatives; Liver Cirrhosis; Neuralgia; Pain Management; Pain, Intractable; Pregabalin | 2014 |
Strategies to prevent the neuropsychiatric side-effects of corticosteroids: a case report and review of the literature.
Topics: Adult; Amines; Benzodiazepines; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Granulomatosis with Polyangiitis; Humans; Lithium Compounds; Lorazepam; Methylprednisolone; Olanzapine; Polyarteritis Nodosa; Prednisone; Psychoses, Substance-Induced | 2014 |
Non-surgical interventions for the management of chronic pelvic pain.
Topics: Amines; Amitriptyline; Analgesics; Chronic Pain; Clonidine; Contraceptive Agents, Female; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Goserelin; Humans; Medroxyprogesterone Acetate; Pain Measurement; Pelvic Pain; Psychotherapy; Randomized Controlled Trials as Topic | 2014 |
Use of natural compounds in the management of diabetic peripheral neuropathy.
Topics: Alkaloids; Amines; Animals; Biological Products; Cannabinoids; Complementary Therapies; Cyclohexanecarboxylic Acids; Diabetes Mellitus; Diabetic Neuropathies; Fatty Acids, Essential; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenols; Pregabalin | 2014 |
What interventions improve walking ability in neurogenic claudication with lumbar spinal stenosis? A systematic review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Bone Density Conservation Agents; Calcitonin; Cyclohexanecarboxylic Acids; Decompression, Surgical; Diclofenac; Gabapentin; gamma-Aminobutyric Acid; Humans; Intermittent Claudication; Lumbar Vertebrae; Physical Therapy Modalities; Prostaglandins; Spinal Stenosis; Walking | 2014 |
Gabapentin's anti-nausea and anti-emetic effects: a review.
Topics: Amines; Animals; Antiemetics; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; MEDLINE; Nausea; Vomiting | 2014 |
Gabapentin for the treatment of substance use disorders.
Topics: Amines; Antimanic Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Substance-Related Disorders; Treatment Outcome | 2013 |
Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline.
Topics: Adult; Amines; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplastic Agents; Baclofen; Comorbidity; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Duloxetine Hydrochloride; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Gels; Humans; Incidence; Ketamine; Neoplasms; Neuralgia; Peripheral Nervous System Diseases; Quality of Life; Randomized Controlled Trials as Topic; Severity of Illness Index; Survivors; Thiophenes; Treatment Outcome; United States | 2014 |
Orthostatic tremor: a review of 45 cases.
Topics: Adult; Aged; Amines; Clonazepam; Cyclohexanecarboxylic Acids; Deep Brain Stimulation; Dizziness; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Retrospective Studies; Tremor | 2014 |
Misuse and abuse of pregabalin and gabapentin: cause for concern?
Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Prescription Drug Misuse; Substance-Related Disorders | 2014 |
Gabapentin for chronic neuropathic pain and fibromyalgia in adults.
Topics: Adult; Amines; Analgesics; Chronic Disease; Chronic Pain; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Randomized Controlled Trials as Topic | 2014 |
Gabapentin for the prophylaxis of episodic migraine in adults.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders | 2014 |
Painful diabetic neuropathy.
Topics: Amines; Analgesics; Analgesics, Opioid; Biopsy; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoglycemic Agents; Pregabalin; Sensory Thresholds; Skin; Thiophenes; Touch Perception | 2014 |
Efficacy and safety of gabapentin 1800 mg treatment for post-herpetic neuralgia: a meta-analysis of randomized controlled trials.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia, Postherpetic; Pain Measurement; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome | 2014 |
Preemptive use of gabapentin in abdominal hysterectomy: a systematic review and meta-analysis.
Topics: Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Preoperative Period | 2014 |
Latest guidelines and advances for treatment of restless legs syndrome.
Topics: Amines; Analgesics, Opioid; Carbamates; Cyclohexanecarboxylic Acids; Dopamine Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Iron Compounds; Pregabalin; Restless Legs Syndrome | 2014 |
A systematic review of pharmacoeconomic studies for pregabalin.
Topics: Amines; Analgesics; Anticonvulsants; Chronic Disease; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Economics, Pharmaceutical; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Health Services; Humans; Neuralgia; Pregabalin; Quality of Life; Quality-Adjusted Life Years; Spain; Sweden; United States | 2015 |
Gabapentin in acute postoperative pain management.
Topics: Acute Pain; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative | 2014 |
[Treatment of pediatric epilepsy].
Topics: Adolescent; Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dioxolanes; Drug Approval; Drug Substitution; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Levetiracetam; Patient Education as Topic; Piracetam; Practice Guidelines as Topic; Topiramate; Triazines; Triazoles; Valproic Acid | 2014 |
[New antiepileptic drugs: characteristics and clinical applications].
Topics: Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dioxolanes; Drug Approval; Drug Interactions; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Japan; Lamotrigine; Levetiracetam; Piracetam; Safety; Topiramate; Triazines; Triazoles | 2014 |
Pain management in Guillain-Barre syndrome: a systematic review.
Topics: Amines; Analgesics; Anti-Inflammatory Agents; Carbamazepine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Humans; Methylprednisolone; Pain Management | 2015 |
Gabapentinoids are effective in decreasing neuropathic pain and other secondary outcomes after spinal cord injury: a meta-analysis.
Topics: Amines; Analgesics; Anxiety; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Depression; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pregabalin; Sleep Disorders, Intrinsic; Spinal Cord Injuries | 2014 |
Pharmacological interventions for preventing post-traumatic stress disorder (PTSD).
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Aged; Amines; Anti-Anxiety Agents; Anti-Inflammatory Agents; Antidepressive Agents, Second-Generation; Citalopram; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocortisone; Middle Aged; Propranolol; Randomized Controlled Trials as Topic; Stress Disorders, Post-Traumatic; Temazepam; Young Adult | 2014 |
Adverse effects of perioperative paracetamol, NSAIDs, glucocorticoids, gabapentinoids and their combinations: a topical review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Drug Combinations; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Humans; Pain, Postoperative | 2014 |
Post-operative analgesic effects of paracetamol, NSAIDs, glucocorticoids, gabapentinoids and their combinations: a topical review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Drug Combinations; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Humans; Pain, Postoperative | 2014 |
[A case of Guillain-Barré syndrome with severe pain successfully controlled with acetaminophen, gabapentin, and parenterally infused fentanyl].
Topics: Acetaminophen; Amines; Child; Cyclohexanecarboxylic Acids; Drug Combinations; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Humans; Infusions, Intravenous; Male; Pain | 2014 |
Antiepileptics for post-herpetic neuralgia in the elderly: current and future prospects.
Topics: Aged; Aged, 80 and over; Amines; Anticonvulsants; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Health Services for the Aged; Humans; Neuralgia, Postherpetic; Polypharmacy; Pregabalin | 2014 |
Potential maternal symptomatic benefit of gabapentin and review of its safety in pregnancy.
Topics: Amines; Anticonvulsants; Birth Weight; Congenital Abnormalities; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperemesis Gravidarum; Pre-Eclampsia; Pregnancy; Premature Birth; Registries; Restless Legs Syndrome | 2014 |
Rational pain management in complex regional pain syndrome 1 (CRPS 1)--a network meta-analysis.
Topics: Adrenal Cortex Hormones; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diphosphonates; Drug Utilization; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Middle Aged; N-Methylaspartate; Pain Management; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Reflex Sympathetic Dystrophy; Treatment Outcome; Vasodilator Agents | 2014 |
Efficacy and safety of pain relief medications after photorefractive keratectomy: review of prospective randomized trials.
Topics: Amines; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Eye Pain; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Photorefractive Keratectomy; Pregabalin; Prospective Studies; Randomized Controlled Trials as Topic; Treatment Outcome | 2014 |
Clinical practice. Postherpetic neuralgia.
Topics: Administration, Topical; Aged; Amines; Analgesics, Opioid; Anesthetics, Local; Antipyretics; Capsaicin; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Herpes Zoster Vaccine; Humans; Lidocaine; Neuralgia, Postherpetic; Pregabalin | 2014 |
A review on the efficacy and safety of gabapentin in the treatment of chronic cough.
Topics: Amines; Antitussive Agents; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia, Postherpetic; Randomized Controlled Trials as Topic | 2015 |
The efficacy of preemptive analgesia for postoperative pain control: a systematic review of the literature.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Pain, Postoperative; Perioperative Nursing | 2015 |
Nortriptyline for neuropathic pain in adults.
Topics: Amines; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Clomipramine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Morphine; Neuralgia; Nortriptyline; Pregabalin; Randomized Controlled Trials as Topic | 2015 |
Gabapentin prophylaxis for postoperative nausea and vomiting in abdominal surgeries: a quantitative analysis of evidence from randomized controlled clinical trials.
Topics: Abdomen; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Postoperative Nausea and Vomiting; Publication Bias | 2015 |
Vulvodynia.
Topics: Administration, Cutaneous; Amines; Analgesics; Anesthetics, Local; Antidepressive Agents; Cyclohexanecarboxylic Acids; Dyspareunia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Nerve Block; Patient Education as Topic; Physical Therapy Modalities; Pregabalin; Vulvodynia | 2015 |
Pharmacological treatment for pain in Guillain-Barré syndrome.
Topics: Amines; Analgesics; Carbamazepine; Constipation; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Humans; Immunoglobulins, Intravenous; Methylprednisolone; Nausea; Pain; Pain Measurement; Randomized Controlled Trials as Topic | 2015 |
Assessment and treatment of insomnia in adult patients with alcohol use disorders.
Topics: Acamprosate; Alcohol Deterrents; Alcoholism; Amines; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Cognitive Behavioral Therapy; Comorbidity; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dyssomnias; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Polysomnography; Quetiapine Fumarate; Sleep Apnea Syndromes; Sleep Initiation and Maintenance Disorders; Stress, Psychological; Taurine; Topiramate; Trazodone | 2015 |
The role of gabapentin in the management of alcohol withdrawal and dependence.
Topics: Alcoholism; Amines; Cyclohexanecarboxylic Acids; Disease Management; Ethanol; Gabapentin; gamma-Aminobutyric Acid; Humans; Prospective Studies; Substance Withdrawal Syndrome | 2015 |
Restless legs syndrome: clinical presentation diagnosis and treatment.
Topics: Amines; Analgesics, Opioid; Benzothiazoles; Cyclohexanecarboxylic Acids; Dopamine Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Methadone; Pramipexole; Restless Legs Syndrome; Tetrahydronaphthalenes; Thiophenes | 2015 |
EMAS position statement: Non-hormonal management of menopausal vasomotor symptoms.
Topics: Amines; Behavior Therapy; Calcium Channel Blockers; Complementary Therapies; Cyclohexanecarboxylic Acids; Diet; Exercise; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Life Style; Menopause; Middle Aged; Selective Serotonin Reuptake Inhibitors; Sweating | 2015 |
Is There a Place for Off-Label Pharmacotherapy in Cannabis Use Disorder? A Review on Efficacy and Safety.
Topics: Acetylcysteine; Amines; Cannabidiol; Cyclohexanecarboxylic Acids; Dronabinol; Drug Combinations; Gabapentin; gamma-Aminobutyric Acid; Humans; Inappropriate Prescribing; Marijuana Abuse; Marijuana Smoking; Off-Label Use; Patient Safety; Practice Patterns, Physicians'; Psychotropic Drugs; Risk Assessment; Risk Factors; Treatment Outcome | 2015 |
Headache and Pain in Guillain-Barré Syndrome.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Headache; Humans; Pain; Posterior Leukoencephalopathy Syndrome; Primary Dysautonomias | 2015 |
Gabapentin in chronic cough.
Topics: Amines; Animals; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Randomized Controlled Trials as Topic | 2015 |
Drug therapy for treating post-dural puncture headache.
Topics: Adrenocorticotropic Hormone; Adult; Amines; Analgesics; Blood Patch, Epidural; Caffeine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocortisone; Male; Middle Aged; Pain Measurement; Post-Dural Puncture Headache; Randomized Controlled Trials as Topic; Spinal Puncture; Sumatriptan; Theophylline; Treatment Outcome | 2015 |
Second-Line Therapy for Endometrial Cancer: The Need for Better Options.
Topics: Adenocarcinoma; Amines; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Endometrial Neoplasms; Estrogen Receptor alpha; Female; Fluorouracil; Gabapentin; gamma-Aminobutyric Acid; Humans; Medical Oncology; Middle Aged; Paclitaxel; Receptors, Progesterone; Rectal Neoplasms; Stroke; TOR Serine-Threonine Kinases; Treatment Outcome | 2015 |
Restless legs syndrome-current therapies and management of augmentation.
Topics: Amines; Analgesics, Opioid; Anticonvulsants; Cyclohexanecarboxylic Acids; Dopamine Agonists; Drug Synergism; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Iron Compounds; Iron Deficiencies; Practice Guidelines as Topic; Pregabalin; Pregnancy; Pregnancy Complications; Restless Legs Syndrome | 2015 |
A systematic review and meta-regression analysis of prophylactic gabapentin for postoperative pain.
Topics: Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; Pain, Postoperative; Postoperative Nausea and Vomiting; Pruritus | 2015 |
Systemic review: the pathogenesis and pharmacological treatment of hiccups.
Topics: Amines; Anticonvulsants; Antipsychotic Agents; Baclofen; Benzamides; Chlorpromazine; Cyclohexanecarboxylic Acids; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Metoclopramide; Randomized Controlled Trials as Topic; Treatment Outcome | 2015 |
Pediatric Insomnia.
Topics: Actigraphy; Adolescent; Amines; Anti-Anxiety Agents; Autism Spectrum Disorder; Central Nervous System Depressants; Child; Cognitive Behavioral Therapy; Comorbidity; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Melatonin; Polysomnography; Sleep Apnea, Obstructive; Sleep Initiation and Maintenance Disorders | 2016 |
The efficacy of gabapentin/pregabalin in improving pain after tonsillectomy: A meta-analysis.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Pain, Postoperative; Pregabalin; Tonsillectomy | 2016 |
[DRUG THERAPY OF NEUROPATHIC PAIN BASED ON THE LATEST RECOMMENDATIONS].
Topics: Amines; Amitriptyline; Analgesics, Non-Narcotic; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Practice Guidelines as Topic; Pregabalin; Thiophenes | 2015 |
Postoperative pain management.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Management; Pain, Postoperative; Pregabalin | 2015 |
Laparoscopic surgery: a narrative review of pharmacotherapy in pain management.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Laparoscopy; Pain Management; Pain, Postoperative; Pregabalin; Receptors, N-Methyl-D-Aspartate | 2015 |
Preventing chronic postoperative pain.
Topics: Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Pain, Postoperative; Pregabalin; Thoracotomy | 2016 |
Pregabalin and gabapentin for the treatment of sciatica.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pregabalin; Sciatica; Treatment Outcome | 2016 |
Management of chronic refractory cough.
Topics: Adaptation, Psychological; Amines; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents; Patient Education as Topic; Practice Guidelines as Topic; Quality of Life; Randomized Controlled Trials as Topic; Speech-Language Pathology | 2015 |
Gabapentin: Abuse, Dependence, and Withdrawal.
Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Substance Abuse Treatment Centers; Substance Withdrawal Syndrome; Substance-Related Disorders | 2016 |
Gabapentin for Chronic Neuropathic Pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Off-Label Use; Pain Measurement; Treatment Outcome | 2015 |
Short-Lasting Unilateral Neuralgiform Headache with Conjunctival Injection and Tearing Secondary to Head and Neck Trauma: Literature Review and Case Report.
Topics: Amines; Central Nervous System Depressants; Craniocerebral Trauma; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Excitatory Amino Acid Antagonists; Exercise Movement Techniques; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Melatonin; Middle Aged; Neck Injuries; Psychotherapy; Temporomandibular Joint Disorders; Trigeminal Autonomic Cephalalgias; Violence | 2016 |
Post-herpetic Neuralgia: a Review.
Topics: Amines; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia, Postherpetic; Practice Guidelines as Topic; Severity of Illness Index; Treatment Outcome | 2016 |
Pain management strategies for neuropathic pain in Fabry disease--a systematic review.
Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Fabry Disease; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Phenytoin | 2016 |
Does preoperative administration of gabapentin/pregabalin improve postoperative nasal surgery pain?
Topics: Adolescent; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Nasal Surgical Procedures; Pain Measurement; Pain, Postoperative; Postoperative Complications; Postoperative Period; Pregabalin; Preoperative Care; Treatment Outcome; Vision Disorders; Young Adult | 2016 |
The Effect of Preoperative Gabapentin on Postoperative Nausea and Vomiting: A Meta-Analysis.
Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Postoperative Nausea and Vomiting; Preoperative Care; Treatment Outcome | 2016 |
Treatment of Cannabis Use Disorder: Current Science and Future Outlook.
Topics: Acetylcysteine; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Health Services Accessibility; Humans; Marijuana Abuse; Psychotherapy | 2016 |
[Preconceptional and perinatal challenges of pregnancy in women with epilepsy].
Topics: Adult; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Parturition; Perinatal Care; Phenobarbital; Phenytoin; Piracetam; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Teratogens; Triazines; Valproic Acid | 2016 |
Chemotherapy-induced painful neuropathy: pain-like behaviours in rodent models and their response to commonly used analgesics.
Topics: Amines; Analgesics, Opioid; Animals; Antidepressive Agents; Antineoplastic Agents; Cisplatin; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Organoplatinum Compounds; Oxaliplatin; Pain; Peripheral Nervous System Diseases; Proteasome Inhibitors; Rodentia; Taxoids | 2016 |
The Effect of Gabapentin on Acute Postoperative Pain in Patients Undergoing Total Knee Arthroplasty: A Meta-Analysis.
Topics: Amines; Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Cyclohexanecarboxylic Acids; Dizziness; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; Pain Measurement; Pain, Postoperative; Pruritus | 2016 |
Gabapentin for the hemodynamic response to intubation: systematic review and meta-analysis.
Topics: Airway Management; Amines; Cyclohexanecarboxylic Acids; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Hemodynamics; Humans; Intubation, Intratracheal; Randomized Controlled Trials as Topic | 2016 |
Gabapentin and pregabalin for the treatment of chronic pruritus.
Topics: Amines; Anti-Anxiety Agents; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Patient Satisfaction; Pregabalin; Pruritus; Quality of Life; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2016 |
Pharmacological Treatment of Pain in Cancer Patients: The Role of Adjuvant Analgesics, a Systematic Review.
Topics: Amines; Analgesics; Anticonvulsants; Antidepressive Agents; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Drug-Related Side Effects and Adverse Reactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Neoplasms; Pain; Pain Management; Treatment Outcome; Triazines | 2017 |
Pharmacological management of spasticity in multiple sclerosis: Systematic review and consensus paper.
Topics: Amines; Analgesics; Baclofen; Cannabidiol; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Diazepam; Dronabinol; Drug Combinations; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Phenol | 2016 |
Can Chronic Pain Be Prevented?
Topics: Acute Pain; Amines; Anesthesia, Conduction; Chronic Pain; Cyclohexanecarboxylic Acids; Epigenesis, Genetic; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Pain, Postoperative; Pregabalin | 2016 |
Gabapentin misuse, abuse and diversion: a systematic review.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Prescription Drug Diversion; Prescription Drug Misuse; Prevalence; Substance-Related Disorders | 2016 |
The use of gabapentin in the management of postoperative pain after total knee arthroplasty: A PRISMA-compliant meta-analysis of randomized controlled trials.
Topics: Amines; Analgesics; Arthroplasty, Replacement, Knee; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Pain, Postoperative; Randomized Controlled Trials as Topic | 2016 |
Alpha
Topics: Amines; Bridged Bicyclo Compounds; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Nervous System Diseases; Pregabalin | 2016 |
The use of gabapentin in the management of postoperative pain after total hip arthroplasty: a meta-analysis of randomised controlled trials.
Topics: Amines; Analgesics; Arthroplasty, Replacement, Hip; Cyclohexanecarboxylic Acids; Disease Management; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Management; Pain Measurement; Pain, Postoperative; Prospective Studies; Randomized Controlled Trials as Topic | 2016 |
Continuous neuropathic pain secondary to endoscopic procedures: report of two cases and review of the literature.
Topics: Adult; Amines; Analgesics; Clonazepam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Laryngoscopy; Male; Middle Aged; Neuralgia; Pain Management; Pain Measurement | 2016 |
Gabapentin for post-operative pain management - a systematic review with meta-analyses and trial sequential analyses.
Topics: Amines; Analgesics; Bias; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative | 2016 |
Comparative efficacy of nonhormonal drugs on menopausal hot flashes.
Topics: Amines; Clonidine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Isoflavones; Menopause; Models, Biological; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors | 2016 |
Gabapentin for Perioperative Analgesia in Otorhinolaryngology-Head and Neck Surgery: Systematic Review.
Topics: Amines; Analgesia; Analgesics; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Head and Neck Neoplasms; Humans; Otolaryngology; Otorhinolaryngologic Surgical Procedures; Pain Measurement; Perioperative Care; Randomized Controlled Trials as Topic; Treatment Outcome | 2016 |
Treating Painful Diabetic Peripheral Neuropathy: An Update.
Topics: Administration, Topical; Amines; Amitriptyline; Analgesics; Analgesics, Opioid; Anesthetics, Local; Capsaicin; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Isosorbide Dinitrate; Lidocaine; Phenols; Pregabalin; Selective Serotonin Reuptake Inhibitors; Sensory System Agents; Serotonin and Noradrenaline Reuptake Inhibitors; Tapentadol; Tramadol; Transcutaneous Electric Nerve Stimulation; Vasodilator Agents; Venlafaxine Hydrochloride | 2016 |
A Meta-Analysis on the Use of Gabapentinoids for the Treatment of Acute Postoperative Pain Following Total Knee Arthroplasty.
Topics: Amines; Analgesics; Arthroplasty, Replacement, Knee; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Pain, Postoperative; Pregabalin; Treatment Outcome | 2016 |
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy.
Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide | 2016 |
Pharmacological Treatment of Cannabis-Related Disorders: A Narrative Review.
Topics: Acetylcysteine; Amines; Animals; Cannabis; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Marijuana Abuse | 2016 |
The efficacy of preoperative administration of gabapentin/pregabalin in improving pain after total hip arthroplasty: a meta-analysis.
Topics: Amines; Analgesics; Arthroplasty, Replacement, Hip; Cyclohexanecarboxylic Acids; Dizziness; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Morphine; Nausea; Pain Management; Pain Measurement; Pain, Postoperative; Pregabalin; Pruritus; Randomized Controlled Trials as Topic; Treatment Outcome; Vomiting | 2016 |
Itch Management: Systemic Agents.
Topics: Amines; Analgesics; Analgesics, Opioid; Anion Exchange Resins; Antidepressive Agents; Aprepitant; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Histamine Antagonists; Humans; Morpholines; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Paraneoplastic Syndromes; Peripheral Nervous System Diseases; Pregabalin; Pruritus; Receptors, Opioid, kappa; Receptors, Opioid, mu; Rifampin; Thalidomide; Uremia; Ursodeoxycholic Acid | 2016 |
Neurologic Itch Management.
Topics: Acupuncture Therapy; Amines; Anesthetics, Local; Anticonvulsants; Antipruritics; Botulinum Toxins, Type A; Calcineurin Inhibitors; Cannabinoid Receptor Agonists; Capsaicin; Cyclohexanecarboxylic Acids; Doxepin; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuromuscular Agents; Peripheral Nervous System Diseases; Phototherapy; Physical Therapy Modalities; Pregabalin; Pruritus; Tacrolimus; Transcranial Magnetic Stimulation; Transcutaneous Electric Nerve Stimulation | 2016 |
Uremic Itch Management.
Topics: Acupuncture Therapy; Amines; Analgesics, Opioid; Anticonvulsants; Calcineurin Inhibitors; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; gamma-Linolenic Acid; Humans; Kidney Failure, Chronic; Morphinans; Narcotic Antagonists; Pregabalin; Pruritus; Receptors, Opioid, kappa; Receptors, Opioid, mu; Renal Dialysis; Spiro Compounds; Tacrolimus; Ultraviolet Therapy; Uremia | 2016 |
Effects of Pregabalin in Patients with Neuropathic Pain Previously Treated with Gabapentin: A Pooled Analysis of Parallel-Group, Randomized, Placebo-controlled Clinical Trials.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic; Sleep; Treatment Outcome | 2017 |
Clinical management of restless legs syndrome in end-stage renal disease patients.
Topics: Amines; Analgesics, Opioid; Benzodiazepines; Benzothiazoles; Comorbidity; Cyclohexanecarboxylic Acids; Dopamine Agonists; Excitatory Amino Acid Antagonists; Exercise Therapy; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Intermittent Pneumatic Compression Devices; Kidney Failure, Chronic; Levodopa; Massage; Pramipexole; Quality of Life; Renal Dialysis; Restless Legs Syndrome; Sleep Hygiene; Tetrahydronaphthalenes; Thiophenes | 2017 |
Analgesia in the surgical intensive care unit.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Local; Clonidine; Critical Care; Cyclohexanecarboxylic Acids; Dexmedetomidine; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydromorphone; Intensive Care Units; Ketamine; Lidocaine; Morphine; Pain; Pain Management; Pain Measurement; Pain, Postoperative; Physical Therapy Modalities | 2017 |
Different doses of gabapentin formulations for postherpetic neuralgia: A systematical review and meta-analysis of randomized controlled trials.
Topics: Amines; Analgesics; Carbamates; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia, Postherpetic; Randomized Controlled Trials as Topic | 2017 |
Interventions for chronic kidney disease-associated restless legs syndrome.
Topics: Amines; Anticonvulsants; Ascorbic Acid; Cyclohexanecarboxylic Acids; Dopamine Agonists; Exercise Therapy; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Iron-Dextran Complex; Levodopa; Quality of Life; Randomized Controlled Trials as Topic; Renal Insufficiency, Chronic; Renal Replacement Therapy; Resistance Training; Restless Legs Syndrome; Vitamin E; Vitamins | 2016 |
Role of Gabapentin in Managing Mucositis Pain in Patients Undergoing Radiation Therapy to the Head and Neck.
Topics: Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Head and Neck Neoplasms; Humans; Male; Middle Aged; Pain; Pain Management; Pain Measurement; Radiotherapy; Radiotherapy Dosage; Retrospective Studies; Risk Assessment; Stomatitis; Treatment Outcome | 2016 |
Are neuromodulating medications effective for the treatment of chronic neurogenic cough?
Topics: Amines; Amitriptyline; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents; Practice Guidelines as Topic; Pregabalin | 2017 |
Hormone Therapy and Other Treatments for Symptoms of Menopause.
Topics: Acupuncture Therapy; Administration, Intravaginal; Amines; Antidepressive Agents; Atrophy; Cyclohexanecarboxylic Acids; Dietary Supplements; Drug Therapy, Combination; Dyspareunia; Estrogen Replacement Therapy; Estrogens; Exercise Therapy; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Hypnosis; Indoles; Menopause; Paroxetine; Progestins; Selective Estrogen Receptor Modulators; Tamoxifen; Vagina; Vaginal Diseases; Vasomotor System; Venlafaxine Hydrochloride | 2016 |
Gabapentin for fibromyalgia pain in adults.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic | 2017 |
An update of management of insomnia in patients with chronic orofacial pain.
Topics: Amines; Anticonvulsants; Antidepressive Agents; Benzodiazepines; Chronic Pain; Cognitive Behavioral Therapy; Cyclohexanecarboxylic Acids; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Melatonin; Orexin Receptor Antagonists; Pregabalin; Sleep Initiation and Maintenance Disorders | 2017 |
Neonatal pain management.
Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Barbiturates; Chronic Pain; Cyclohexanecarboxylic Acids; Dexmedetomidine; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Infant, Newborn; Intensive Care Units, Neonatal; Kangaroo-Mother Care Method; Ketamine; Lorazepam; Midazolam; Neonatal Abstinence Syndrome; Pain Management; Pain Measurement; Palliative Care; Propofol; Sucking Behavior; Sucrose; Terminal Care | 2017 |
Abuse and Misuse of Pregabalin and Gabapentin.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Overdose; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Substance-Related Disorders | 2017 |
An update on the pharmacologic management and treatment of neuropathic pain.
Topics: Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Cannabinoids; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Medical History Taking; Neuralgia; Pain Management; Physical Examination; Pregabalin; Serotonin and Noradrenaline Reuptake Inhibitors; Transcutaneous Electric Nerve Stimulation | 2017 |
Gabapentinoids for chronic low back pain: a protocol for systematic review and meta-analysis of randomised controlled trials.
Topics: Amines; Chronic Pain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Neuralgia; Pain Management; Pain Measurement; Pregabalin; Randomized Controlled Trials as Topic; Research Design; Systematic Reviews as Topic | 2016 |
Neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Narcotics; Neoplasms; Neuralgia; Nociceptive Pain; Pain Management; Pregabalin; Quality of Life; Tramadol; Transcutaneous Electric Nerve Stimulation; Voltage-Gated Sodium Channel Blockers | 2017 |
Unveiling the relative efficacy, safety and tolerability of prophylactic medications for migraine: pairwise and network-meta analysis.
Topics: Adult; Amines; Amitriptyline; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizziness; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Migraine Disorders; Nausea; Pre-Exposure Prophylaxis; Propranolol; Randomized Controlled Trials as Topic; Topiramate; Treatment Outcome; Valproic Acid | 2017 |
Burning mouth syndrome: a systematic review of treatments.
Topics: Amines; Analgesics; Antioxidants; Burning Mouth Syndrome; Capsaicin; Clonazepam; Cyclohexanecarboxylic Acids; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Psychotherapy; Sensory System Agents; Thioctic Acid | 2018 |
The Role of Multimodal Analgesia in Spine Surgery.
Topics: Acetaminophen; Amines; Analgesia; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Drug Administration Routes; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Management; Pain, Postoperative; Pregabalin; Spine | 2017 |
Clinical application of perioperative multimodal analgesia.
Topics: Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Dexamethasone; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Magnesium; Pain Management; Pain, Postoperative | 2017 |
Biological rationale and potential clinical use of gabapentin and pregabalin in bipolar disorder, insomnia and anxiety: protocol for a systematic review and meta-analysis.
Topics: Amines; Anti-Anxiety Agents; Anxiety Disorders; Bipolar Disorder; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders; Systematic Reviews as Topic; Treatment Outcome | 2017 |
Gabapentin can decrease acute pain and morphine consumption in spinal surgery patients: A meta-analysis of randomized controlled trials.
Topics: Acute Pain; Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; Pain Measurement; Pain, Postoperative; Randomized Controlled Trials as Topic; Spine | 2017 |
Multiple outcomes and analyses in clinical trials create challenges for interpretation and research synthesis.
Topics: Amines; Analgesics; Antipsychotic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Outcome Assessment, Health Care; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Treatment Outcome | 2017 |
Advances in the management of diabetic neuropathy.
Topics: Adjuvants, Immunologic; Amines; Anticonvulsants; Antidepressive Agents; Antioxidants; Cardiovascular Diseases; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Randomized Controlled Trials as Topic; Thiamine; Thioctic Acid; Treatment Outcome | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; N-Methylaspartate; Pain, Postoperative; Postoperative Care; Pregabalin; Tramadol | 2017 |
Gabapentin for chronic neuropathic pain in adults.
Topics: Adult; Amines; Analgesics; Chronic Disease; Chronic Pain; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Neuralgia, Postherpetic; Numbers Needed To Treat; Randomized Controlled Trials as Topic | 2017 |
Gabapentin in procedure-specific postoperative pain management - preplanned subgroup analyses from a systematic review with meta-analyses and trial sequential analyses.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Randomized Controlled Trials as Topic; Surgical Procedures, Operative; Visual Analog Scale | 2017 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Treatment of Uremic Pruritus: A Systematic Review.
Topics: Administration, Cutaneous; Amines; Analgesics; Anti-Asthmatic Agents; Antipruritics; Capsaicin; Cromolyn Sodium; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Phototherapy; Pregabalin; Pruritus; Renal Dialysis; Renal Insufficiency, Chronic; Uremia | 2017 |
Therapeutical approaches to paroxysmal hemicrania, hemicrania continua and short lasting unilateral neuralgiform headache attacks: a critical appraisal.
Topics: Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Lamotrigine; Lidocaine; Male; Neuralgia; Paroxysmal Hemicrania; Reproducibility of Results; SUNCT Syndrome; Surveys and Questionnaires; Topiramate; Triazines; Trigeminal Autonomic Cephalalgias | 2017 |
Interventions for Neuropathic Pain: An Overview of Systematic Reviews.
Topics: Amines; Analgesics; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Neuralgia, Postherpetic; Randomized Controlled Trials as Topic | 2017 |
Update in perioperative medicine: practice changing evidence published in 2016.
Topics: Amines; Analgesics; Anticoagulants; Antipsychotic Agents; Arthritis, Rheumatoid; Blood Transfusion; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Delirium; Disease Progression; Evidence-Based Practice; Gabapentin; gamma-Aminobutyric Acid; Haloperidol; Hemorrhage; Humans; Pain, Postoperative; Perioperative Care; Postoperative Complications; Practice Guidelines as Topic; Risk Assessment; Surgical Wound Infection; Thromboembolism; Tumor Necrosis Factor-alpha | 2017 |
Preoperative pregabalin or gabapentin for acute and chronic postoperative pain among patients undergoing breast cancer surgery: A systematic review and meta-analysis of randomized controlled trials.
Topics: Amines; Analgesics; Breast Neoplasms; Chronic Pain; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mastectomy; Pain, Postoperative; Perioperative Care; Pregabalin; Randomized Controlled Trials as Topic | 2017 |
Chronic Hiccups: An Underestimated Problem.
Topics: Amines; Anesthesiology; Baclofen; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Muscle Relaxants, Central | 2017 |
Antidepressants for chronic non-cancer pain in children and adolescents.
Topics: Abdominal Pain; Adolescent; Amines; Amitriptyline; Analgesics; Antidepressive Agents; Child; Chronic Pain; Citalopram; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Dyspepsia; Gabapentin; gamma-Aminobutyric Acid; Humans; Irritable Bowel Syndrome; Neuralgia; Placebos; Randomized Controlled Trials as Topic | 2017 |
Antiepileptic drugs for chronic non-cancer pain in children and adolescents.
Topics: Adolescent; Amines; Amitriptyline; Anticonvulsants; Child; Chronic Pain; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic | 2017 |
Is gabapentin effective and safe in open hysterectomy? A PRISMA compliant meta-analysis of randomized controlled trials.
Topics: Amines; Analgesia; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Incidence; Pain Management; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Placebos; Postoperative Nausea and Vomiting; Randomized Controlled Trials as Topic; Treatment Outcome | 2017 |
Benefits and safety of gabapentinoids in chronic low back pain: A systematic review and meta-analysis of randomized controlled trials.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; England; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Pregabalin; Randomized Controlled Trials as Topic | 2017 |
Cherry-picking by trialists and meta-analysts can drive conclusions about intervention efficacy.
Topics: Amines; Bias; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Meta-Analysis as Topic; Neuralgia; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Treatment Outcome | 2017 |
Gabapentin enacarbil, pregabalin and rotigotine are equally effective in restless legs syndrome: a comparative meta-analysis.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dopamine Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Restless Legs Syndrome; Tetrahydronaphthalenes; Thiophenes; Treatment Outcome | 2017 |
The efficacy of gabapentin in reducing pain intensity and postoperative nausea and vomiting following laparoscopic cholecystectomy: A meta-analysis.
Topics: Amines; Analgesics; Cholecystectomy, Laparoscopic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Randomized Controlled Trials as Topic; Treatment Outcome | 2017 |
A meta-analysis of the preoperative use of gabapentinoids for the treatment of acute postoperative pain following spinal surgery.
Topics: Acute Pain; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Pregabalin; Randomized Controlled Trials as Topic; Spine | 2017 |
How addictive are gabapentin and pregabalin? A systematic review.
Topics: Amines; Analgesics; Behavior, Addictive; Cyclohexanecarboxylic Acids; Databases, Bibliographic; Drug Overdose; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Self Administration; Substance-Related Disorders | 2017 |
WITHDRAWN: Anticonvulsants for fibromyalgia.
Topics: Acetamides; Amines; Anticonvulsants; Conflict of Interest; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Lacosamide; Levetiracetam; Piracetam; Pregabalin | 2017 |
Negative myoclonus induced by gabapentin and pregabalin: A case series and systematic literature review.
Topics: Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Myoclonus; Pregabalin; Prospective Studies; Registries; Retrospective Studies; Young Adult | 2017 |
Advances in pharmacotherapies for movement disorders in children: current limitations and future progress.
Topics: Amines; Anti-Dyskinesia Agents; Child; Clonidine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Movement Disorders; Precision Medicine; Treatment Outcome | 2017 |
The Efficacy of Preoperative Gabapentin in Spinal Surgery: A Meta-Analysis of Randomized Controlled Trials.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Preoperative Care; Randomized Controlled Trials as Topic; Spine | 2017 |
Gabapentin for the treatment of alcohol use disorder.
Topics: Alcohol Drinking; Alcoholism; Amines; Animals; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome | 2018 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Pharmacotherapy for Neuropathic Pain in Japan.
Topics: Aged; Algorithms; Amines; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Japan; Neuralgia; Pain Management; Pregabalin | 2017 |
Use of α2δ Ligands for Restless Legs Syndrome/Willis Ekbom Disease.
Topics: Animals; Anticonvulsants; Calcium Channels; Carbamates; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Pregabalin; Restless Legs Syndrome | 2018 |
Interventions for eye movement disorders due to acquired brain injury.
Topics: 4-Aminopyridine; Abducens Nerve Diseases; Amifampridine; Amines; Baclofen; Botulinum Toxins; Brain Injuries; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuromuscular Agents; Nystagmus, Pathologic; Ocular Motility Disorders; Randomized Controlled Trials as Topic; Vision, Binocular; Watchful Waiting | 2018 |
Extended-release drug formulations for the treatment of epilepsy.
Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Drug Compounding; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Triazines | 2018 |
Analgesic mechanisms of gabapentinoids and effects in experimental pain models: a narrative review.
Topics: Analgesics; Animals; Calcium Channels; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain, Postoperative; Pregabalin | 2018 |
Pharmacological therapies for management of opium withdrawal.
Topics: Amantadine; Amines; Baclofen; Buprenorphine; Clonidine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Methadone; Opioid-Related Disorders; Opium; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Tramadol | 2018 |
Pruritus in Cutaneous T-Cell Lymphoma and Its Management.
Topics: Adrenal Cortex Hormones; Amines; Antidepressive Agents, Tricyclic; Antipruritics; Cyclohexanecarboxylic Acids; Emollients; Gabapentin; gamma-Aminobutyric Acid; Histamine Antagonists; Humans; Lymphoma, T-Cell, Cutaneous; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Pruritus; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Surveys and Questionnaires; Visual Analog Scale | 2018 |
End-Stage Renal Disease Chronic Itch and Its Management.
Topics: Amines; Analgesics, Opioid; Anticonvulsants; Antipruritics; Chronic Disease; Cyclohexanecarboxylic Acids; Emollients; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Nalbuphine; Narcotic Antagonists; Pregabalin; Pruritus; Quality of Life; Renal Dialysis; Severity of Illness Index; Ultraviolet Therapy | 2018 |
On the addictive power of gabapentinoids: a mini-review.
Topics: Adult; Amines; Animals; Comorbidity; Craving; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Methadone; Narcotics; Opiate Substitution Treatment; Pregabalin; Reward; Substance Withdrawal Syndrome; Substance-Related Disorders | 2018 |
Interventions for treating acute high altitude illness.
Topics: Acetazolamide; Acute Disease; Adolescent; Adult; Altitude Sickness; Amines; Anticonvulsants; Atmospheric Pressure; Cyclohexanecarboxylic Acids; Dexamethasone; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Humans; Hypertension, Pulmonary; Magnesium; Randomized Controlled Trials as Topic | 2018 |
A Meta-Analysis of Therapeutic Efficacy and Safety of Gabapentin in the Treatment of Postherpetic Neuralgia from Randomized Controlled Trials.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia, Postherpetic; Randomized Controlled Trials as Topic | 2018 |
Updates on Multimodal Analgesia for Orthopedic Surgery.
Topics: Acetaminophen; Amines; Analgesia; Celecoxib; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ibuprofen; Ketamine; Ketorolac; Orthopedic Procedures; Pain, Postoperative | 2018 |
The efficacy of gabapentin in reducing pain intensity and morphine consumption after breast cancer surgery: A meta-analysis.
Topics: Amines; Breast Neoplasms; Chronic Pain; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mastectomy; Morphine; Pain Measurement; Pain, Postoperative; Preoperative Care; Randomized Controlled Trials as Topic | 2018 |
Gabapentin add-on treatment for drug-resistant focal epilepsy.
Topics: Adult; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Intention to Treat Analysis; Randomized Controlled Trials as Topic | 2018 |
Efficacy of gabapentin in the treatment of trigeminal neuralgia: A systematic review of randomized controlled trials.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Randomized Controlled Trials as Topic; Trigeminal Neuralgia | 2019 |
Gabapentin add-on treatment for drug-resistant focal epilepsy.
Topics: Adult; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Intention to Treat Analysis; Patient Dropouts; Randomized Controlled Trials as Topic | 2021 |
Derivatization of γ-Amino Butyric Acid Analogues for Their Determination in the Biological Samples and Pharmaceutical Preparations: A Comprehensive Review.
Topics: Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Pharmaceutical Preparations; Pregabalin; Vigabatrin | 2022 |
Lesser Known Uses of γ-Aminobutyric Acid Analogue Medications in Otolaryngology.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Otolaryngology; Pregabalin; Trismus | 2022 |
Is gabapentin a safe and effective treatment for nonneuropathic pain?
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia | 2021 |
Gabapentin and pregabalin in bipolar disorder, anxiety states, and insomnia: Systematic review, meta-analysis, and rationale.
Topics: Amines; Anxiety; Bipolar Disorder; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders | 2022 |
Is gabapentin effective and safe in the treatment of chronic pelvic pain in women: a systematic review and meta-analysis.
Topics: Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pelvic Pain | 2022 |
Effects of Gabapentin and Pregabalin on Calcium Homeostasis: Implications for Physical Rehabilitation of Musculoskeletal Tissues.
Topics: Calcium; Gabapentin; gamma-Aminobutyric Acid; Homeostasis; Humans; Pregabalin | 2022 |
Gabapentin-Friend or foe?
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid | 2023 |
Gabapentin-Induced Overflow Urinary Incontinence: A Case Report and Review of the Literature.
Topics: Amines; Analgesics; Carcinoma, Non-Small-Cell Lung; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lung Neoplasms; Male; Middle Aged; Neuralgia; Pregabalin; Urinary Incontinence | 2023 |
The safety and efficacy of gabapentinoids in the management of neuropathic pain: a systematic review with meta-analysis of randomised controlled trials.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pregabalin; Randomized Controlled Trials as Topic | 2023 |
Prophylactic gabapentin during head and neck cancer therapy: a systematic review and meta-analysis.
Topics: Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Head and Neck Neoplasms; Humans; Pain; Weight Loss | 2023 |
585 trial(s) available for gabapentin and gamma-aminobutyric acid
| Article | Year |
|---|---|
Selected CSF biochemistry and gabapentin concentrations in the CSF and plasma in patients with partial seizures after a single oral dose of gabapentin.
Topics: Acetates; Administration, Oral; Adult; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Serotonin | 1992 |
Long-term treatment with gabapentin for partial epilepsy.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Research Design; Time Factors | 1992 |
Gabapentin.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drugs, Investigational; Epilepsies, Partial; Epilepsy, Generalized; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 1991 |
Gabapentin in partial epilepsy. UK Gabapentin Study Group.
Topics: Acetates; Adolescent; Adult; Amines; Analysis of Variance; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Time Factors | 1990 |
Gabapentin as an antiepileptic drug in man.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Patient Compliance; Random Allocation | 1987 |
Evaluation of encephalotropic and psychotropic properties of gabapentin in man by pharmaco-EEG and psychometry.
Topics: Acetates; Adult; Affect; Amines; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Memory; Psychological Tests; Psychomotor Performance; Random Allocation | 1986 |
Gabapentin toxicity in children manifesting as behavioral changes.
Topics: Acetates; Affect; Aggression; Amines; Anticonvulsants; Behavior; Child; Cyclohexanecarboxylic Acids; Epilepsy, Complex Partial; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Seizures; Treatment Outcome | 1995 |
Long-term study with gabapentin in patients with drug-resistant epileptic seizures.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Placebos | 1994 |
The long-term safety and efficacy of gabapentin (Neurontin) as add-on therapy in drug-resistant partial epilepsy. The US Gabapentin Study Group.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Long-Term Care; Male; Middle Aged; Substance Withdrawal Syndrome | 1994 |
Gabapentin as add-on therapy in refractory partial epilepsy: a double-blind, placebo-controlled, parallel-group study. The US Gabapentin Study Group No. 5.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Analysis of Variance; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 1993 |
Seizure frequency and CSF parameters in a double-blind placebo controlled trial of gabapentin in patients with intractable complex partial seizures.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Placebo Effect; Seizures; Time Factors; Treatment Outcome | 1995 |
The effect of gabapentin on brain gamma-aminobutyric acid in patients with epilepsy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Protons; Treatment Outcome | 1996 |
[Gabapentin (Neurontin): a new possibility in the add-on therapy of partial epilepsies].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic | 1996 |
[Clinical studies on gabapentin in Switzerland].
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Male; Quality of Life; Switzerland | 1996 |
Gabapentin adjunctive therapy in neuropathic pain states.
Topics: Acetates; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Facial Pain; Female; Gabapentin; gamma-Aminobutyric Acid; Herpesviridae Infections; HIV Infections; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Neuralgia; Pain, Intractable; Peripheral Nervous System Diseases | 1996 |
Effect of gabapentin (Neurontin) [corrected] on mood and well-being in patients with epilepsy.
Topics: Acetates; Adult; Affect; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Quality of Life | 1996 |
Effect of a high-protein meal on gabapentin pharmacokinetics.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dietary Proteins; Eating; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 1996 |
Gabapentin in generalized seizures.
Topics: Acetates; Adolescent; Adult; Amines; Analysis of Variance; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsy, Generalized; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome | 1996 |
Placebo-controlled trial of gabapentin in patients with amyotrophic lateral sclerosis. WALS Study Group. Western Amyotrophic Lateral Sclerosis Study Group.
Topics: Acetates; Adult; Aged; Amines; Amyotrophic Lateral Sclerosis; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 1996 |
Gabapentin in the treatment of bipolar disorder.
Topics: Acetates; Adult; Ambulatory Care; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome | 1997 |
Effectiveness of gabapentin in controlling spasticity: a quantitative study.
Topics: Acetates; Adult; Amines; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Electromyography; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Movement; Muscle Spasticity; Parasympatholytics; Spinal Cord Injuries | 1997 |
Treatment of restless legs syndrome with gabapentin.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Restless Legs Syndrome | 1997 |
Gabapentin in naive childhood absence epilepsy: results from two double-blind, placebo-controlled, multicenter studies.
Topics: Acetates; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Monitoring; Electroencephalography; Epilepsy, Absence; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Treatment Outcome | 1996 |
Gabapentin and cognition: a double blind, dose ranging, placebo controlled study in refractory epilepsy.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Analysis of Variance; Anticonvulsants; Cognition Disorders; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuropsychological Tests | 1997 |
Gabapentin for relief of upper motor neuron symptoms in multiple sclerosis.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Cramp; Muscle Spasticity; Treatment Outcome | 1997 |
A double-blind controlled study of gabapentin and baclofen as treatment for acquired nystagmus.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Double-Blind Method; Eye Movements; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nystagmus, Pathologic; Treatment Outcome; Visual Acuity | 1997 |
Gabapentin for parkinsonism: a double-blind, placebo-controlled, crossover trial.
Topics: Acetates; Adult; Aged; Amines; Antiparkinson Agents; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Electromyography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Parkinson Disease, Secondary; Tremor | 1997 |
A pilot trial of adjunctive gabapentin in the treatment of bipolar disorder.
Topics: Acetates; Adjuvants, Pharmaceutic; Adult; Affect; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pilot Projects; Treatment Outcome | 1997 |
Gabapentin and motor fluctuations in Parkinson's disease.
Topics: Acetates; Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Motor Activity; Movement Disorders; Parkinson Disease; Treatment Outcome | 1997 |
The effect of gabapentin on neuropathic pain.
Topics: Acetates; Adolescent; Adult; Amines; Analgesics; Child; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Middle Aged; Myofascial Pain Syndromes; Pain; Peripheral Nervous System Diseases; Retrospective Studies | 1997 |
Gabapentin monotherapy: I. An 8-day, double-blind, dose-controlled, multicenter study in hospitalized patients with refractory complex partial or secondarily generalized seizures. The US Gabapentin Study Group 88/89.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Epilepsy, Complex Partial; Epilepsy, Generalized; Female; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Male; Middle Aged; Treatment Outcome | 1997 |
Gabapentin monotherapy: II. A 26-week, double-blind, dose-controlled, multicenter study of conversion from polytherapy in outpatients with refractory complex partial or secondarily generalized seizures. The US Gabapentin Study Group 82/83.
Topics: Acetates; Adolescent; Adult; Ambulatory Care; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy, Complex Partial; Epilepsy, Generalized; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Patient Dropouts; Placebos; Treatment Outcome | 1997 |
Gabapentin for the treatment of spasticity in patients with spinal cord injury.
Topics: Acetates; Administration, Oral; Adult; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Muscle Spasticity; Paralysis; Prognosis; Prospective Studies; Reflex; Reproducibility of Results; Spinal Cord Injuries; Treatment Outcome | 1997 |
Open label gabapentin treatment for pain in multiple sclerosis.
Topics: Acetates; Adult; Aged; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Pain; Pain, Intractable | 1997 |
High dose gabapentin in refractory partial epilepsy: clinical observations in 50 patients.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diarrhea; Diplopia; Dizziness; Dose-Response Relationship, Drug; Epilepsies, Myoclonic; Epilepsies, Partial; Fatigue; Female; Flatulence; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Male; Middle Aged; Seizures | 1998 |
Gabapentin: long-term antianxiety and hypnotic effects in psychiatric patients with comorbid anxiety-related disorders.
Topics: Acetates; Adult; Aged; Amines; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Behavioral Symptoms; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mental Disorders; Middle Aged; Prospective Studies; Psychotropic Drugs; Treatment Outcome | 1998 |
Gabapentin absorption: effect of mixing with foods of varying macronutrient composition.
Topics: Acetates; Adult; Amines; Anticonvulsants; Area Under Curve; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Female; Food-Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 1998 |
Gabapentin does not interact with a contraceptive regimen of norethindrone acetate and ethinyl estradiol.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Contraceptives, Oral, Synthetic; Cross-Over Studies; Cyclohexanecarboxylic Acids; Drug Interactions; Estradiol Congeners; Ethinyl Estradiol; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Norethindrone | 1998 |
Conversion to high dose gabapentin monotherapy in patients with medically refractory partial epilepsy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medical Records; Middle Aged; Therapeutic Equivalency; Treatment Outcome | 1998 |
Oral gabapentin disposition in patients with epilepsy after a high-protein meal.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dietary Proteins; Epilepsy; Fasting; Female; Food-Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Saliva | 1997 |
Outcome evaluation of gabapentin as add-on therapy for partial seizures. "NEON" Study Investigators Group. Neurontin Evaluation of Outcomes in Neurological Practice.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurologic Examination; Phenobarbital; Phenytoin; Primidone; Quality of Life; Valproic Acid | 1998 |
Double-blind controlled trial of gabapentin in essential tremor.
Topics: Acetates; Activities of Daily Living; Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Motor Skills; Neurologic Examination; Tremor | 1998 |
Gabapentin and carbamazepine affect eye movements and posture control differently: a placebo-controlled investigation of acute CNS side effects in healthy volunteers.
Topics: Acetates; Administration, Oral; Adult; Amines; Anticonvulsants; Carbamazepine; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Electronystagmography; Electrooculography; Eye Movements; Female; Fingers; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Humans; Isometric Contraction; Male; Middle Aged; Placebos; Posture; Prospective Studies; Saccades; Time Factors | 1998 |
Gabapentin bioavailability: effect of dose and frequency of administration in adult patients with epilepsy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Biological Availability; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 1998 |
Gabapentin for treatment of pain and tremor: a large case series.
Topics: Acetates; Adult; Aged; Amines; Analgesics; Anticonvulsants; Arachnoiditis; Cerebellar Neoplasms; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Migraine Disorders; Pain; Peripheral Nervous System Diseases; Prospective Studies; Restless Legs Syndrome; Tremor; Trigeminal Neuralgia | 1998 |
Gabapentin in orthostatic tremor: results of a double-blind crossover with placebo in four patients.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Electromyography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Posture; Treatment Outcome; Tremor | 1998 |
Pharmacological control of facilitatory I-wave interaction in the human motor cortex. A paired transcranial magnetic stimulation study.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Central Nervous System Depressants; Cyclohexanecarboxylic Acids; Electric Stimulation; Ethanol; Evoked Potentials, Motor; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lorazepam; Male; Motor Cortex; Neural Inhibition; Phenobarbital; Transcranial Magnetic Stimulation; Triazines; Vigabatrin | 1998 |
Gabapentin augmentation for fluoxetine-treated patients with obsessive-compulsive disorder.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Obsessive-Compulsive Disorder; Pilot Projects; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 1998 |
Effects of gabapentin on cognition and quality of life in patients with epilepsy.
Topics: Acetates; Adult; Affect; Aged; Amines; Anticonvulsants; Cognition; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuropsychological Tests; Quality of Life; Seizures; Statistics, Nonparametric | 1998 |
Adjunctive therapy in epilepsy with new antiepileptic drugs: is it of any value?
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Clobazam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Humans; Lamotrigine; Male; Patient Compliance; Patient Satisfaction; Prospective Studies; Quality of Life; Triazines; Vigabatrin | 1998 |
Gabapentin treatment of alcohol withdrawal.
Topics: Acetates; Adult; Alcohol Withdrawal Delirium; Alcoholism; Ambulatory Care; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Ethanol; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Substance Withdrawal Syndrome; Treatment Outcome | 1998 |
Effects of gabapentin on the different components of peripheral and central neuropathic pain syndromes: a pilot study.
Topics: Acetates; Amines; Analgesics; Anticonvulsants; Central Nervous System Diseases; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Pain Threshold; Peripheral Nervous System Diseases; Pilot Projects; Psychophysics; Stress, Mechanical; Syndrome; Touch | 1998 |
A double-blind trial of gabapentin monotherapy for newly diagnosed partial seizures. International Gabapentin Monotherapy Study Group 945-77.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medical Records; Middle Aged; Seizures | 1998 |
Gabapentin for the symptomatic treatment of painful neuropathy in patients with diabetes mellitus: a randomized controlled trial.
Topics: Acetates; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Quality of Life | 1998 |
Gabapentin for the treatment of postherpetic neuralgia: a randomized controlled trial.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Quality of Life | 1998 |
The natural history and the effects of gabapentin in amyotrophic lateral sclerosis.
Topics: Acetates; Administration, Oral; Adult; Aged; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; Disability Evaluation; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Prognosis; Survival Analysis; Survival Rate | 1998 |
Gabapentin does not alter single-dose lithium pharmacokinetics.
Topics: Acetates; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Depression; Double-Blind Method; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Metabolic Clearance Rate | 1998 |
Gabapentin add-on treatment: how many patients become seizure-free? An open-label multicenter study.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Quality of Life; Seizures; Treatment Outcome | 1999 |
Cognitive effects of topiramate, gabapentin, and lamotrigine in healthy young adults.
Topics: Acetates; Adult; Affect; Amines; Anticonvulsants; Cognition Disorders; Cyclohexanecarboxylic Acids; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Neuropsychological Tests; Psychomotor Performance; Reaction Time; Single-Blind Method; Topiramate; Triazines; Word Association Tests | 1999 |
An audit of the perceived efficacy and tolerability of gabapentin therapy in an out-patient cohort with chronic epilepsy.
Topics: Acetates; Adult; Ambulatory Care; Amines; Anticonvulsants; Chronic Disease; Cohort Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medical Audit; Retrospective Studies; Treatment Outcome | 1999 |
Gabapentin in the treatment of refractory partial epilepsy in children with intellectual disability.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Retrospective Studies; Severity of Illness Index | 1998 |
Gabapentin in the treatment of painful diabetic neuropathy: a placebo controlled, double blind, crossover trial.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement | 1999 |
A randomized placebo-controlled comparative trial of gabapentin and propranolol in essential tremor.
Topics: Acetates; Administration, Oral; Aged; Amines; Antiparkinson Agents; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Propranolol; Sympatholytics; Treatment Outcome; Tremor | 1999 |
Effects of age and gender on single-dose pharmacokinetics of gabapentin.
Topics: Acetates; Administration, Oral; Adult; Age Distribution; Age Factors; Aged; Amines; Anticonvulsants; Body Constitution; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney; Kidney Function Tests; Male; Middle Aged; Regression Analysis; Sex Factors | 1999 |
Clinical experience with gabapentin in patients with bipolar or schizoaffective disorder: results of an open-label study.
Topics: Acetates; Acute Disease; Adult; Aged; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Treatment Outcome | 1999 |
Cognitive abilities and adjustment with gabapentin: results of a multisite study.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsy, Complex Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuropsychological Tests | 1999 |
Gabapentin as an adjuvant to opioid analgesia for neuropathic cancer pain.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasms; Pain Measurement; Pain, Intractable | 1999 |
[Gabapentin in the treatment of mania].
Topics: Acetates; Amines; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Clozapine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales | 1999 |
Safety and tolerability of gabapentin as adjunctive therapy in a large, multicenter study.
Topics: Acetates; Adolescent; Adult; Ambulatory Care; Amines; Anticonvulsants; Asthenia; Carbamazepine; Cyclohexanecarboxylic Acids; Dizziness; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Male; Patient Dropouts; Phenytoin; Prospective Studies; Treatment Outcome; Valproic Acid | 1999 |
[Visual field defects due to antiepileptic drugs].
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Vigabatrin; Vision Disorders; Visual Field Tests; Visual Fields | 1999 |
Treatment of social phobia with gabapentin: a placebo-controlled study.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Personality Inventory; Phobic Disorders; Treatment Outcome | 1999 |
Low dose gabapentin for shoulder-hand syndrome induced by phenobarbital: a three-month study.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Phenobarbital; Reflex Sympathetic Dystrophy | 1999 |
A beneficial effect on mood in partial epilepsy patients treated with gabapentin.
Topics: Acetates; Adult; Affect; Aged; Amines; Anticonvulsants; Anxiety Disorders; Comorbidity; Cyclohexanecarboxylic Acids; Depressive Disorder; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Personality Inventory; Prospective Studies; Psychiatric Status Rating Scales; Treatment Outcome | 1999 |
Gabapentin as add-on therapy in children with refractory partial seizures: a 12-week, multicentre, double-blind, placebo-controlled study. Gabapentin Paediatric Study Group.
Topics: Acetates; Age Factors; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Placebos; Treatment Outcome | 1999 |
Treatment of alcohol withdrawal syndrome with gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Central Nervous System Depressants; Chlormethiazole; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Ethanol; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Substance Withdrawal Syndrome; Treatment Outcome | 1999 |
Gabapentin does not affect antipyrine clearance.
Topics: Acetates; Adult; Amines; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antipyrine; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Male; Phenytoin; Saliva | 1999 |
Differential cognitive effects of carbamazepine and gabapentin.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Attention; Carbamazepine; Cognition; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electroencephalography; Evoked Potentials; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Memory; Middle Aged; Neuropsychological Tests | 1999 |
Randomized double-blind study comparing the efficacy of gabapentin with amitriptyline on diabetic peripheral neuropathy pain.
Topics: Acetates; Adrenergic Uptake Inhibitors; Aged; Amines; Amitriptyline; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Prospective Studies; Severity of Illness Index; Treatment Outcome | 1999 |
Clinical experience using adjunctive gabapentin in treatment-resistant bipolar mixed states.
Topics: Acetates; Adjuvants, Pharmaceutic; Adult; Aged; Amines; Analysis of Variance; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome | 1999 |
Lamotrigine in the treatment of bipolar depression.
Topics: Acetates; Affect; Amines; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Cross-Over Studies; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Triazines | 1999 |
Monotherapy trials with gabapentin for partial epilepsy.
Topics: Acetates; Ambulatory Care; Amines; Anticonvulsants; Carbamazepine; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Multicenter Studies as Topic; Placebos; Randomized Controlled Trials as Topic; Treatment Outcome | 1999 |
Dosing to efficacy with neurontin: the STEPS trial. Study of Titration to Effect Profile of Safety.
Topics: Acetates; Adult; Amines; Anticonvulsants; Clinical Trials, Phase III as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Practice Patterns, Physicians'; Product Surveillance, Postmarketing; Prospective Studies; Treatment Outcome | 1999 |
Gabapentin as adjunctive therapy for partial seizures.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dizziness; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Patient Dropouts; Phenytoin; Prospective Studies; Quality of Life; Sleep Stages; Treatment Outcome | 1999 |
Postherpetic neuralgia: role of gabapentin and other treatment modalities.
Topics: Acetates; Administration, Topical; Age Factors; Aged; Ambulatory Care; Amines; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Capsaicin; Carbamazepine; Clinical Trials as Topic; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Narcotics; Neuralgia; Pain; Risk Factors; Severity of Illness Index; Treatment Outcome | 1999 |
Gabapentin monotherapy for the symptomatic treatment of painful neuropathy: a multicenter, double-blind, placebo-controlled trial in patients with diabetes mellitus.
Topics: Acetates; Affect; Ambulatory Care; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Placebos; Quality of Life; Treatment Outcome | 1999 |
Gabapentin as an adjunct to standard mood stabilizers in outpatients with mixed bipolar symptomatology.
Topics: Acetates; Adult; Affect; Aged; Ambulatory Care; Amines; Antidepressive Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Disorders of Excessive Somnolence; Drug Therapy, Combination; Female; Follow-Up Studies; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Time Factors; Treatment Outcome | 1999 |
Gabapentin in childhood epilepsy: a prospective evaluation of efficacy and safety.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Male; Prospective Studies | 2000 |
Gabapentin treatment for insomnia associated with alcohol dependence.
Topics: Acetates; Adult; Alcoholism; Amines; Anticonvulsants; Comorbidity; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Sleep Initiation and Maintenance Disorders; Temperance; Treatment Outcome | 2000 |
Pharmacologic reversal of cortical hyperexcitability in patients with ALS.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Cerebral Cortex; Cyclohexanecarboxylic Acids; Diazepam; Drug Therapy, Combination; Evoked Potentials, Motor; Female; GABA Agonists; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetics; Male; Middle Aged; Neural Inhibition; Neuroprotective Agents; Physical Stimulation; Riluzole; Synaptic Transmission; Treatment Outcome | 2000 |
Effectiveness of gabapentin for the treatment of behavioral disorders in dementia.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Anti-Anxiety Agents; Behavioral Symptoms; Cyclohexanecarboxylic Acids; Dementia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Prospective Studies; Psychomotor Agitation | 2000 |
Conversion from thrice daily to twice daily administration of gabapentin (GBP) in partial epilepsy: analysis of clinical efficacy and plasma levels.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Polypharmacy; Treatment Outcome | 2000 |
Gabapentin effect on spasticity in multiple sclerosis: a placebo-controlled, randomized trial.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Disability Evaluation; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Fatigue; Muscle Spasticity; Prospective Studies; Treatment Outcome | 2000 |
Gabapentin treatment for posttraumatic stress disorder.
Topics: Acetates; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Stress Disorders, Post-Traumatic | 2000 |
Effect of anticonvulsants on nocturnal sleep in epilepsy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Circadian Rhythm; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Sleep; Triazines | 2000 |
Inter- and intra-subject variability in gabapentin absorption and absolute bioavailability.
Topics: Acetates; Adult; Amines; Analysis of Variance; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Monitoring; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Prospective Studies | 2000 |
Treatment of chronic: new perspectives.
Topics: Acetates; Aged; Amines; Cerebral Infarction; Chronic Disease; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Male; Middle Aged | 1999 |
Gabapentin enhances the analgesic effect of morphine in healthy volunteers.
Topics: Acetates; Amines; Analgesia; Analgesics; Analgesics, Opioid; Area Under Curve; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Morphine; Pain Threshold | 2000 |
Gabapentin is effective in treating nocturnal painful spasms in multiple sclerosis.
Topics: Acetates; Amines; Anticonvulsants; Circadian Rhythm; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Multiple Sclerosis; Pain; Spasm; Time Factors | 2000 |
Efficacy of gabapentin as adjunctive therapy in a large, multicenter study. The Steps Study Group.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsies, Partial; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Treatment Outcome | 2000 |
Gabapentin therapy for diabetic neuropathic pain.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Treatment Outcome | 2000 |
Placebo-controlled study of gabapentin treatment of panic disorder.
Topics: Acetates; Adolescent; Adult; Aged; Agoraphobia; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Panic Disorder; Psychiatric Status Rating Scales; Sex Characteristics | 2000 |
Gabapentin for essential tremor: a multiple-dose, double-blind, placebo-controlled trial.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Antiparkinson Agents; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Essential Tremor; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurologic Examination; Treatment Outcome | 2000 |
Gabapentin vs. amitriptyline in painful diabetic neuropathy: an open-label pilot study.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Ataxia; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Dizziness; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Paresthesia; Pilot Projects; Salivary Glands; Sleep Stages; Treatment Outcome | 2000 |
Gabapentin versus vigabatrin as first add-on for patients with partial seizures that failed to respond to monotherapy: a randomized, double-blind, dose titration study. GREAT Study Investigators Group. Gabapentin in Refractory Epilepsy Add-on Treatment.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Research Design; Retrospective Studies; Treatment Outcome; Vigabatrin | 2000 |
Low doses of gabapentin may be helpful in the management of chronic daily headache.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Male; Middle Aged; Patient Satisfaction; Treatment Outcome | 2000 |
A placebo-controlled study of lamotrigine and gabapentin monotherapy in refractory mood disorders.
Topics: Acetates; Adult; Amines; Antimanic Agents; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Mood Disorders; Placebos; Psychiatric Status Rating Scales; Treatment Outcome; Triazines | 2000 |
Adjunctive gabapentin treatment of bipolar disorder.
Topics: Acetates; Adult; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome | 2000 |
Increased seizures after discontinuing carbamazepine: results from the gabapentin monotherapy trial.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Seizures; Substance Withdrawal Syndrome | 2000 |
Gabapentin in the treatment of cocaine dependence: a case series.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Behavior, Addictive; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Personality Inventory; Pilot Projects; Psychiatric Status Rating Scales; Severity of Illness Index; Substance Abuse Detection; Surveys and Questionnaires; Treatment Outcome | 2001 |
Gabapentin in bipolar disorder: a placebo-controlled trial of adjunctive therapy. Gabapentin Bipolar Disorder Study Group.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium Carbonate; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid | 2000 |
Efficacy of gabapentin in migraine prophylaxis.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Migraine Disorders | 2001 |
Topiramate as add-on treatment for patients with bipolar mania.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Body Mass Index; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Male; Middle Aged; Topiramate; Treatment Outcome; Valproic Acid | 1999 |
Gabapentin in the acute treatment of refractory bipolar disorder.
Topics: Acetates; Acute Disease; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Prospective Studies; Time Factors; Treatment Outcome | 1999 |
Oral gabapentin (neurontin) treatment of refractory genitourinary tract pain.
Topics: Acetates; Administration, Oral; Amines; Analgesics; Cyclohexanecarboxylic Acids; Cystitis, Interstitial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain | 2001 |
Rapid initiation of gabapentin: a randomized, controlled trial.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Time Factors | 2001 |
Phase III randomized trial of gabapentin in patients with amyotrophic lateral sclerosis.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Sample Size; Survival Analysis | 2001 |
Gabapentin as add-on therapy in children with refractory partial seizures: a 24-week, multicentre, open-label study.
Topics: Acetates; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Patient Dropouts; Treatment Failure | 2001 |
Single-dose gabapentin pharmacokinetics and safety in healthy infants and children.
Topics: Acetates; Administration, Oral; Amines; Anticonvulsants; Area Under Curve; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Infant; Male; Metabolic Clearance Rate; Regression Analysis | 2001 |
A randomized open-label study of gabapentin and lamotrigine in adults with learning disability and resistant epilepsy.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Lamotrigine; Male; Middle Aged; Severity of Illness Index; Treatment Outcome; Triazines | 2001 |
Gabapentin but not vigabatrin is effective in the treatment of acquired nystagmus in multiple sclerosis: How valid is the GABAergic hypothesis?
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Electrooculography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Nystagmus, Physiologic; Vigabatrin; Visual Acuity | 2001 |
Comparative cognitive effects of carbamazepine and gabapentin in healthy senior adults.
Topics: Acetates; Age Factors; Aged; Amines; Anticonvulsants; Attention; Carbamazepine; Cognition; Cognition Disorders; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Health Status; Humans; Incidence; Male; Middle Aged; Neuropsychological Tests | 2001 |
Myoclonus in epilepsy patients with anticonvulsive add-on therapy with pregabalin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Electroencephalography; Electromyography; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Humans; Incidence; Male; Myoclonus; Pregabalin; Randomized Controlled Trials as Topic | 2001 |
A crossover study of gabapentin in treatment of restless legs syndrome among hemodialysis patients.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Renal Dialysis; Restless Legs Syndrome; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome | 2001 |
Efficacy and safety of gabapentin as an add-on therapy in refractory partial epileptic patients.
Topics: Acetates; Activities of Daily Living; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Statistics, Nonparametric; Treatment Outcome | 2001 |
Gabapentin for the treatment of patients with somatization disorder.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Psychiatric Status Rating Scales; Somatoform Disorders; Treatment Outcome | 2001 |
Gabapentin in the treatment of hemifacial spasm.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hemifacial Spasm; Humans; Male; Middle Aged; Pilot Projects; Treatment Outcome | 2001 |
Gabapentin as a possible treatment of behavioral alterations in Alzheimer disease (AD) patients.
Topics: Acetates; Aged; Alzheimer Disease; Amines; Behavior; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Agonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 2001 |
Drug-resistant cluster headache responding to gabapentin: a pilot study.
Topics: Acetates; Adult; Amines; Analgesics; Cluster Headache; Cyclohexanecarboxylic Acids; Drug Resistance; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pilot Projects | 2001 |
A placebo-controlled trial of gabapentin in spinal muscular atrophy.
Topics: Acetates; Adult; Amines; Arm; Cyclohexanecarboxylic Acids; Double-Blind Method; Excitatory Amino Acid Antagonists; Feasibility Studies; Female; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Humans; Male; Muscle Contraction; Severity of Illness Index; Sickness Impact Profile; Spinal Muscular Atrophies of Childhood; Treatment Outcome; United States; Vital Capacity | 2001 |
Gabapentin in postherpetic neuralgia: a randomised, double blind, placebo controlled study.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Patient Satisfaction; Quality of Life; Treatment Outcome | 2001 |
Treatment of idiopathic restless legs syndrome (RLS) with gabapentin.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Polysomnography; Restless Legs Syndrome | 2001 |
Modification of cortical excitability induced by gabapentin: a study by transcranial magnetic stimulation.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cerebral Cortex; Cyclohexanecarboxylic Acids; Electric Stimulation; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Transcranial Magnetic Stimulation | 2001 |
Population pharmacokinetics of gabapentin in infants and children.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Body Weight; Child; Child, Preschool; Creatinine; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Metabolic Clearance Rate; Reference Values | 2001 |
Brain metabolic changes during lactate-induced panic: effects of gabapentin treatment.
Topics: Acetates; Adult; Amines; Arousal; Aspartic Acid; Brain; Cyclohexanecarboxylic Acids; Double-Blind Method; Energy Metabolism; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusions, Intravenous; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Panic; Panic Disorder; Treatment Outcome | 2001 |
Gabapentin in PTSD: a retrospective, clinical series of adjunctive therapy.
Topics: Acetates; Adult; Aged; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Retrospective Studies; Sleep Wake Disorders; Stress Disorders, Post-Traumatic; Treatment Outcome | 2001 |
Gabapentin's effect on agitation in severely and persistently mentally ill patients.
Topics: Acetates; Amines; Antimanic Agents; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mental Disorders; Middle Aged; Mood Disorders; Pilot Projects; Psychiatric Status Rating Scales; Psychomotor Agitation; Psychotic Disorders; Retrospective Studies; Time Factors | 2002 |
Clinical predictors of response to lamotrigine and gabapentin monotherapy in refractory affective disorders.
Topics: Acetates; Adult; Aged; Amines; Antidepressive Agents; Cross-Over Studies; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Resistance; Female; Forecasting; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Mood Disorders; Recurrence; Retrospective Studies; Triazines | 2002 |
Modulation of cerebral GABA by topiramate, lamotrigine, and gabapentin in healthy adults.
Topics: Acetates; Adult; Amines; Anticonvulsants; Brain Chemistry; Cerebral Cortex; Cyclohexanecarboxylic Acids; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Topiramate; Triazines | 2002 |
The evolving role of topiramate among other mood stabilizers in the management of bipolar disorder.
Topics: Acetates; Acute Disease; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Randomized Controlled Trials as Topic; Topiramate; Triazines; Valproic Acid | 2001 |
Gabapentin attenuates superior oblique myokymia.
Topics: Acetates; Administration, Oral; Adult; Amines; Cyclohexanecarboxylic Acids; Diplopia; Excitatory Amino Acid Antagonists; Eye Movements; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome; Trochlear Nerve Diseases | 2002 |
Third generation anticonvulsants in bipolar disorder: a review of efficacy and summary of clinical recommendations.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Double-Blind Method; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Placebos; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2002 |
Gabapentin for relief of neuropathic pain related to anticancer treatment: a preliminary study.
Topics: Acetates; Adolescent; Amines; Analgesics; Antineoplastic Agents; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasms; Pain; Pain Measurement; Palliative Care; Prospective Studies | 2002 |
Effects of gabapentin and carbamazepine on the EEG and cognition in healthy volunteers.
Topics: Acetates; Adolescent; Adult; Alpha Rhythm; Amines; Anticonvulsants; Brain; Carbamazepine; Cognition; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electroencephalography; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuropsychological Tests; Regression Analysis | 2002 |
Gabapentin in the treatment of neuropathic pain after spinal cord injury: a prospective, randomized, double-blind, crossover trial.
Topics: Acetates; Adult; Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Prospective Studies; Spinal Cord Injuries; Time Factors; Trauma Severity Indices; Treatment Outcome | 2002 |
[Gabapentin as therapy for vulvitis].
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Treatment Outcome; Vulvitis | 2002 |
Gabapentin versus lamotrigine monotherapy: a double-blind comparison in newly diagnosed epilepsy.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Asthenia; Clinical Protocols; Cyclohexanecarboxylic Acids; Dizziness; Double-Blind Method; Epilepsies, Partial; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Lamotrigine; Male; Middle Aged; Patient Dropouts; Proportional Hazards Models; Survival Analysis; Treatment Outcome; Triazines | 2002 |
A randomized study of the effects of single-dose gabapentin versus placebo on postoperative pain and morphine consumption after mastectomy.
Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mastectomy; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Treatment Outcome | 2002 |
Post-partum cerebral angiopathy: repetitive TCD, MRI, MRA, and EEG examinations.
Topics: Acetates; Adult; Amines; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Aspirin; Brain Edema; Cerebral Angiography; Cerebral Arteries; Cerebral Hemorrhage; Cerebrovascular Circulation; Cyclohexanecarboxylic Acids; Echoencephalography; Eclampsia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Observer Variation; Oxytocin; Postpartum Period; Pregnancy; Sensitivity and Specificity; Time Factors; Ultrasonography, Doppler, Transcranial | 2002 |
The analgesic effect of gabapentin and mexiletine after breast surgery for cancer.
Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Antineoplastic Agents; Breast Neoplasms; Chronic Disease; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mastectomy, Radical; Mexiletine; Middle Aged; Pain Measurement; Pain, Postoperative; Surveys and Questionnaires; Time Factors | 2002 |
Gabapentin and lamotrigine in Indian patients of partial epilepsy refractory to carbamazepine.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; India; Lamotrigine; Male; Middle Aged; Triazines | 2002 |
Gabapentin in neuropathic pain syndromes: a randomised, double-blind, placebo-controlled trial.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analysis of Variance; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Quality of Life; Syndrome | 2002 |
Pilot evaluation of gabapentin for treating hot flashes.
Topics: Acetates; Adolescent; Adult; Amines; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Middle Aged; Pilot Projects; Probability; Prospective Studies; Single-Blind Method; Treatment Outcome | 2002 |
Treatment of restless legs syndrome with gabapentin: a double-blind, cross-over study.
Topics: Acetates; Adult; Aged; Amines; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Polysomnography; Random Allocation; Research Design; Restless Legs Syndrome; Sample Size; Sleep; Treatment Outcome | 2002 |
Gabapentin for the treatment of pain in guillain-barré syndrome: a double-blinded, placebo-controlled, crossover study.
Topics: Acetates; Adult; Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Humans; Middle Aged; Pain | 2002 |
Gabapentin augmentation therapy in bipolar depression.
Topics: Acetates; Adult; Amines; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Clozapine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium Carbonate; Male; Pilot Projects; Prospective Studies; Severity of Illness Index; Surveys and Questionnaires | 2002 |
The absorption of gabapentin following high dose escalation.
Topics: Absorption; Acetates; Amines; Anticonvulsants; Biological Availability; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Interactions; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Saliva | 2003 |
Gabapentin in late-onset poststroke seizures.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Prospective Studies; Recurrence; Seizures; Stroke | 2002 |
Gabapentin's effects on hot flashes in postmenopausal women: a randomized controlled trial.
Topics: Acetates; Administration, Oral; Amines; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Middle Aged; Patient Satisfaction; Postmenopause; Probability; Quality of Life; Reference Values; Severity of Illness Index; Treatment Outcome | 2003 |
Gabapentin effect on neuropathic pain compared among patients with spinal cord injury and different durations of symptoms.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Polyradiculopathy; Sleep; Spinal Cord Injuries; Treatment Outcome | 2003 |
Characterization of gabapentin overdose using a poison center case series.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Overdose; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Male; Middle Aged; Poison Control Centers; Prospective Studies; Treatment Outcome | 2003 |
Effect of gabapentin on nausea induced by chemotherapy in patients with breast cancer.
Topics: Acetates; Administration, Oral; Amines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclohexanecarboxylic Acids; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Nausea | 2003 |
Gabapentin in antipsychotic-induced tardive dyskinesia: results of 1-year follow-up.
Topics: Acetates; Adult; Amines; Anticonvulsants; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Dyskinesia, Drug-Induced; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychotic Disorders; Schizophrenia; Treatment Outcome | 2003 |
Effects of gabapentin on anxiety induced by simulated public speaking.
Topics: Acetates; Adolescent; Adult; Amines; Anti-Anxiety Agents; Anxiety; Blood Pressure; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Humans; Male; Speech | 2003 |
Serum concentrations and effects of gabapentin and vigabatrin: observations from a dose titration study.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Monitoring; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Vigabatrin | 2003 |
Open pilot study of gabapentin versus trazodone to treat insomnia in alcoholic outpatients.
Topics: Acetates; Alcoholism; Amines; Antidepressive Agents, Second-Generation; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Outpatients; Pilot Projects; Sleep Initiation and Maintenance Disorders; Sleep Stages; Trazodone | 2003 |
Use of gabapentin to reduce chronic neuropathic pain in Fabry disease.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fabry Disease; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Pain Measurement; Treatment Outcome | 2003 |
Role of gabapentin in spinal muscular atrophy: results of a multicenter, randomized Italian study.
Topics: Acetates; Adolescent; Adult; Amines; Arm; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Isometric Contraction; Italy; Leg; Male; Middle Aged; Movement; Muscle, Skeletal; Neuroprotective Agents; Spinal Muscular Atrophies of Childhood; Treatment Outcome; Vital Capacity | 2003 |
Gabapentin versus ropinirole in the treatment of idiopathic restless legs syndrome.
Topics: Acetates; Adult; Aged; Amines; Calcium Channel Blockers; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dopamine Agonists; Drug Administration Schedule; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Male; Middle Aged; Pilot Projects; Polysomnography; Restless Legs Syndrome; Surveys and Questionnaires | 2003 |
Treatment of acute alcohol withdrawal with gabapentin: results from a controlled two-center trial.
Topics: Acetates; Adult; Alcoholism; Amines; Analysis of Variance; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Substance Withdrawal Syndrome | 2003 |
Gabapentin in the management of pentazocine dependence: a potent analgesic--anticraving agent.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Anti-Anxiety Agents; Clonidine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain; Pentazocine; Substance Withdrawal Syndrome; Substance-Related Disorders | 2003 |
Gabapentin for the treatment of behavioural alterations in dementia: preliminary 15-month investigation.
Topics: Acetates; Aged; Amines; Anti-Anxiety Agents; Comorbidity; Cyclohexanecarboxylic Acids; Dementia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mental Disorders; Treatment Outcome | 2003 |
Gabapentin in the prophylaxis of chronic daily headache: a randomized, placebo-controlled study.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Analgesics; Anticonvulsants; Ataxia; Chronic Disease; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dizziness; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders; Humans; Male; Middle Aged; Pain Measurement; Quality of Life; Safety; Sleep Stages; Treatment Outcome | 2003 |
The effects of remifentanil and gabapentin on hyperalgesia in a new extended inflammatory skin pain model in healthy volunteers.
Topics: Acetates; Adult; Amines; Analgesics, Opioid; Cross-Over Studies; Cyclohexanecarboxylic Acids; Diazepam; Double-Blind Method; Drug Synergism; Excitatory Amino Acid Antagonists; Female; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Inflammation; Male; Pain Measurement; Pain Threshold; Physical Stimulation; Piperidines; Reaction Time; Remifentanil; Skin; Sunburn; Treatment Outcome | 2004 |
Gabapentin reduces cocaine use among addicts from a community clinic sample.
Topics: Acetates; Adult; Amines; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Diagnosis, Dual (Psychiatry); Diagnostic and Statistical Manual of Mental Disorders; Excitatory Amino Acid Agonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mental Disorders; Outpatients; Substance Abuse Treatment Centers; Treatment Outcome | 2004 |
Lidocaine patch 5% with systemic analgesics such as gabapentin: a rational polypharmacy approach for the treatment of chronic pain.
Topics: Acetates; Activities of Daily Living; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Chronic Disease; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Low Back Pain; Male; Middle Aged; Neuralgia; Pain; Pain Measurement; Pilot Projects; Quality of Life; Treatment Outcome | 2003 |
Gabapentin in the management of the recurrent, refractory, idiopathic priapism.
Topics: Acetates; Adult; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pilot Projects; Priapism; Recurrence; Regional Blood Flow | 2004 |
Effects of gabapentin on postoperative morphine consumption and pain after abdominal hysterectomy: a randomized, double-blind trial.
Topics: Acetates; Adult; Aged; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Dizziness; Double-Blind Method; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Placebos; Postoperative Nausea and Vomiting; Premedication; Sleep Stages; Treatment Outcome | 2004 |
Pilot study using gabapentin for tamoxifen-induced hot flashes in women with breast cancer.
Topics: Acetates; Administration, Oral; Amines; Breast Neoplasms; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Pilot Projects; Selective Estrogen Receptor Modulators; Severity of Illness Index; Tamoxifen; Treatment Outcome | 2004 |
Gabapentin maintenance decreases smoked cocaine-related subjective effects, but not self-administration by humans.
Topics: Acetates; Adult; Amines; Blood Pressure; Choice Behavior; Cocaine; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Humans; Male; Self Administration; Smoking; Surveys and Questionnaires | 2004 |
Preemptive use of gabapentin significantly decreases postoperative pain and rescue analgesic requirements in laparoscopic cholecystectomy.
Topics: Acetates; Adult; Amines; Analgesia; Analgesics; Analgesics, Opioid; Analysis of Variance; Anesthetics, Intravenous; Cholecystectomy; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Laparoscopy; Male; Pain Measurement; Pain, Postoperative; Time Factors; Tramadol; Treatment Outcome | 2004 |
Gabapentin to control seizures in children undergoing cancer treatment.
Topics: Acetates; Amines; Anticonvulsants; Antineoplastic Agents; Brain; Child; Cyclohexanecarboxylic Acids; Electroencephalography; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neoplasms; Radiotherapy; Seizures; Severity of Illness Index | 2004 |
Gabapentin for painful legs and moving toes syndrome.
Topics: Acetates; Aged; Amines; Cyclohexanecarboxylic Acids; Electromyography; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Leg; Magnetic Resonance Imaging; Male; Movement Disorders; Pain; Syndrome; Toes | 2004 |
Analgesic effects of gabapentin after spinal surgery.
Topics: Acetates; Acute Disease; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Intervertebral Disc; Lumbar Vertebrae; Middle Aged; Morphine; Pain, Postoperative; Spinal Fusion | 2004 |
Gabapentin is a first line drug for the treatment of neuropathic pain in spinal cord injury.
Topics: Acetates; Adult; Aged; Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Disability Evaluation; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Prospective Studies; Quality of Life; Sleep; Spinal Cord Injuries; Treatment Outcome | 2004 |
Add-on gabapentin in the treatment of opiate withdrawal.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Heroin; Heroin Dependence; Humans; Male; Naltrexone; Narcotic Antagonists; Narcotics; Recurrence; Substance Withdrawal Syndrome | 2004 |
The analgesic effects of gabapentin after total abdominal hysterectomy.
Topics: Acetates; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Blood Pressure; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Humans; Hysterectomy; Middle Aged; Monitoring, Intraoperative; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Respiratory Mechanics; Tramadol | 2004 |
Use of gabapentin for attenuation of symptoms following rapid opiate detoxification (ROD)--correlation with neurophysiological parameters--.
Topics: Acetates; Adult; Amines; Anesthesia; Anesthetics, Intravenous; Cyclohexanecarboxylic Acids; Electric Stimulation; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Heroin Dependence; Hormone Antagonists; Humans; Magnesium; Male; Median Nerve; Methadone; Naltrexone; Narcotic Antagonists; Narcotics; Potassium; Propofol; Restless Legs Syndrome; Somatostatin; Substance Withdrawal Syndrome; Water-Electrolyte Balance | 2004 |
Clinical efficacy of gabapentin for paroxysmal symptoms in multiple sclerosis.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Peripheral Nervous System Diseases | 2004 |
Treatment of ataxia in cortical cerebellar atrophy with the GABAergic drug gabapentin. A preliminary study.
Topics: Acetates; Aged; Amines; Antiparkinson Agents; Atrophy; Cerebellar Ataxia; Cerebellar Cortex; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuropsychological Tests; Statistics, Nonparametric; Time | 2004 |
Gabapentin for neuropathic cancer pain: a randomized controlled trial from the Gabapentin Cancer Pain Study Group.
Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasm Invasiveness; Nerve Compression Syndromes; Nervous System Neoplasms; Pain; Pain Measurement; Treatment Outcome | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Monitoring, Intraoperative; Otorhinolaryngologic Surgical Procedures; Pain Measurement; Pain, Postoperative; Paranasal Sinuses; Propofol; Rhinoplasty | 2004 |
Therapeutic outcome in neuropathic pain: relationship to evidence of nervous system lesion.
Topics: Acetates; Adult; Aged; Amines; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Depression; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Imipramine; Male; Middle Aged; Pain; Pain Measurement; Sensation Disorders; Trauma, Nervous System; Treatment Outcome | 2004 |
Gabapentin for the prevention of postoperative pain after vaginal hysterectomy.
Topics: Acetates; Adult; Amines; Calcium Channel Blockers; Case-Control Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Hysterectomy, Vaginal; Male; Middle Aged; Narcotics; Oxazepam; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Time Factors | 2004 |
Randomised controlled trial of gabapentin in Complex Regional Pain Syndrome type 1 [ISRCTN84121379].
Topics: Adult; Aged; Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Reflex Sympathetic Dystrophy; Sickness Impact Profile; Somatosensory Disorders | 2004 |
Gabapentin versus levodopa for the treatment of Restless Legs Syndrome in hemodialysis patients: an open-label study.
Topics: Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dopamine Agonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Levodopa; Male; Middle Aged; Quality of Life; Renal Dialysis; Restless Legs Syndrome; Severity of Illness Index; Treatment Outcome | 2004 |
A placebo-controlled trial of gabapentin for painful HIV-associated sensory neuropathies.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; HIV Seropositivity; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Peripheral Nervous System Diseases; Sleep; Time Factors; Treatment Outcome | 2004 |
Chronic oral gabapentin reduces elements of central sensitization in human experimental hyperalgesia.
Topics: Adult; Amines; Analgesics; Capsaicin; Central Nervous System; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Injections, Intradermal; Male; Pain Measurement; Physical Stimulation | 2004 |
Preemptive gabapentin decreases postoperative pain after lumbar discoidectomy.
Topics: Adult; Amines; Analgesics; Analgesics, Opioid; Analysis of Variance; Cyclohexanecarboxylic Acids; Diskectomy; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Lumbar Vertebrae; Male; Pain Measurement; Pain, Postoperative; Preoperative Care; Time Factors | 2004 |
Gabapentin therapy for pruritus in haemodialysis patients: a randomized, placebo-controlled, double-blind trial.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pruritus; Renal Dialysis; Uremia | 2004 |
Pharmacokinetics of gabapentin in paediatric patients with uncontrolled seizures.
Topics: Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy, Partial, Sensory; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Multivariate Analysis; Time Factors | 2004 |
A placebo-controlled randomized clinical trial of perioperative administration of gabapentin, rofecoxib and their combination for spontaneous and movement-evoked pain after abdominal hysterectomy.
Topics: Adult; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Lactones; Male; Middle Aged; Morphine; Movement; Pain Measurement; Pain, Postoperative; Retrospective Studies; Sulfones; Surveys and Questionnaires; Time Factors; Treatment Outcome | 2005 |
Treatment of diabetic neuropathic pain with gabapentin alone or combined with vitamin B complex. preliminary results.
Topics: Activities of Daily Living; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Prospective Studies; Vitamin B Complex | 2004 |
[Gabapentin for spasticity: a randomized, double-blind, placebo-controlled trial].
Topics: Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Muscle Spasticity; Parasympatholytics | 2005 |
Gabapentin can improve postural stability and quality of life in primary orthostatic tremor.
Topics: Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Electromyography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Skeletal; Posture; Pressure; Quality of Life; Surveys and Questionnaires; Tremor | 2005 |
A medication screening trial evaluation of reserpine, gabapentin and lamotrigine pharmacotherapy of cocaine dependence.
Topics: Adult; Amines; Anticonvulsants; Antipsychotic Agents; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Patient Compliance; Reserpine; Triazines | 2005 |
Oxcarbazepine monotherapy in postherpetic neuralgia unresponsive to carbamazepine and gabapentin.
Topics: Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Resistance; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Oxcarbazepine; Pain; Patient Satisfaction; Quality of Life; Treatment Outcome | 2005 |
Effects of topiramate and gabapentin on cognitive abilities in healthy volunteers.
Topics: Activities of Daily Living; Adult; Amines; Anticonvulsants; Brain; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Maximum Tolerated Dose; Middle Aged; Neuropsychological Tests; Patient Selection; Reference Values; Risk Factors; Topiramate; Treatment Outcome | 2005 |
[Curative effect of gabapentin on refractory epilepsy].
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsy, Generalized; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2005 |
Morphine, gabapentin, or their combination for neuropathic pain.
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Analgesics, Opioid; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Morphine; Neuralgia; Pain Measurement; Treatment Outcome | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexanecarboxylic Acids; Diskectomy; Double-Blind Method; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Lumbar Vertebrae; Male; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting | 2005 |
Preoperative gabapentin decreases anxiety and improves early functional recovery from knee surgery.
Topics: Adult; Amines; Anterior Cruciate Ligament; Anxiety; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain, Postoperative; Premedication | 2005 |
New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine.
Topics: Aged; Aging; Amines; Anticonvulsants; Carbamazepine; Cerebral Infarction; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Hospitals, Veterans; Humans; Lamotrigine; Patient Compliance; Patient Selection; Treatment Outcome; Triazines; United States; United States Department of Veterans Affairs | 2005 |
The comparative evaluation of gabapentin and carbamazepine for pain management in Guillain-Barré syndrome patients in the intensive care unit.
Topics: Adult; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Carbamazepine; Conscious Sedation; Critical Care; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Humans; Male; Pain; Pain Measurement; Prospective Studies | 2005 |
Effect of preemptive gabapentin on postoperative pain relief and morphine consumption following lumbar laminectomy and discectomy: a randomized, double-blinded, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Diskectomy; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Laminectomy; Male; Middle Aged; Morphine; Pain, Postoperative; Prospective Studies | 2005 |
Starting dose of gabapentin for patients with post-herpetic neuralgia--a dose-response study.
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Neuralgia | 2005 |
A single dose of gabapentin reduces acute pain and allodynia in patients with herpes zoster.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Hyperalgesia; Male; Middle Aged; Pain Measurement; Pain Threshold; Treatment Outcome | 2005 |
Gabapentin for the symptomatic treatment of chronic neuropathic pain in patients with late-stage lyme borreliosis: a pilot study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Lyme Neuroborreliosis; Male; Middle Aged; Neuralgia; Pain Measurement; Pilot Projects; Prospective Studies; Risk Assessment; Severity of Illness Index; Single-Blind Method; Treatment Outcome | 2005 |
Smoked cocaine discrimination in humans: effects of gabapentin.
Topics: Administration, Inhalation; Adult; Amines; Arousal; Cocaine; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Discrimination Learning; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Psychomotor Performance | 2005 |
A randomized placebo-controlled trial of gabapentin for cocaine dependence.
Topics: Adult; Amines; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Patient Compliance; Secondary Prevention; Surveys and Questionnaires | 2006 |
Gabapentin provides effective postoperative analgesia whether administered pre-emptively or post-incision.
Topics: Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nephrectomy; Pain Measurement; Pain, Postoperative; Prospective Studies | 2005 |
A randomized, open-label pilot comparison of gabapentin and bupropion SR for smoking cessation.
Topics: Adolescent; Adult; Amines; Bupropion; Cyclohexanecarboxylic Acids; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Sample Size; Smoking Cessation; Substance Withdrawal Syndrome; Tobacco Use Disorder; Treatment Outcome | 2005 |
Multimodal analgesia with gabapentin and local anesthetics prevents acute and chronic pain after breast surgery for cancer.
Topics: Acute Disease; Adult; Amines; Analgesia; Anesthetics, Local; Breast Neoplasms; Chronic Disease; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain, Postoperative | 2005 |
Gabapentin reduces rectal mechanosensitivity and increases rectal compliance in patients with diarrhoea-predominant irritable bowel syndrome.
Topics: Adult; Amines; Analgesics; Compliance; Cyclohexanecarboxylic Acids; Diarrhea; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Irritable Bowel Syndrome; Pain Measurement; Rectum; Sensory Thresholds; Surveys and Questionnaires | 2005 |
The acute effects of gabapentin in combination with alcohol in heavy drinkers.
Topics: Adult; Alcoholic Intoxication; Alcoholism; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Ethanol; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Humans; Male; Mental Recall; Motivation; Neuropsychological Tests; Postural Balance; Premedication; Psychomotor Performance; Verbal Learning | 2006 |
Pharmacological modulation of pain-related brain activity during normal and central sensitization states in humans.
Topics: Adult; Amines; Analgesics; Analysis of Variance; Capsaicin; Central Nervous System; Cross-Over Studies; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Magnetic Resonance Imaging; Male; Pain; Psychophysics | 2005 |
Gabapentin is effective in the treatment of cancer-related neuropathic pain: a prospective, open-label study.
Topics: Aged; Amines; Analgesics; Analysis of Variance; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasms; Pain; Peripheral Nervous System Diseases; Prospective Studies; Treatment Outcome; United Kingdom | 2005 |
Effect of oral gabapentin on postoperative epidural analgesia.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Amines; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analgesics, Non-Narcotic; Cyclohexanecarboxylic Acids; Dizziness; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Leg; Middle Aged; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Statistics as Topic | 2006 |
Weight variations in the prophylactic therapy of primary headaches: 6-month follow-up.
Topics: Adrenergic beta-Antagonists; Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants; Atenolol; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Migraine with Aura; Migraine without Aura; Pizotyline; Propranolol; Tension-Type Headache; Valproic Acid; Vasodilator Agents; Verapamil; Weight Gain | 2005 |
Gabapentin: an alternative to the cyclooxygenase-2 inhibitors for perioperative pain management.
Topics: Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain, Postoperative; Perioperative Care; Statistics, Nonparametric | 2006 |
Chronic pelvic pain treated with gabapentin and amitriptyline: a randomized controlled pilot study.
Topics: Adult; Amines; Amitriptyline; Austria; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Combinations; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain Measurement; Pelvic Pain; Pilot Projects; Treatment Outcome; Women's Health | 2005 |
Gabapentin attenuates late but not acute pain after abdominal hysterectomy.
Topics: Acetaminophen; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Codeine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Morphine; Pain Measurement; Pain, Postoperative | 2006 |
Duloxetine versus routine care in the long-term management of diabetic peripheral neuropathic pain.
Topics: Amines; Amitriptyline; Analysis of Variance; Cyclohexanecarboxylic Acids; Cyclohexanols; Diabetic Neuropathies; Double-Blind Method; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride | 2006 |
Preemptive gabapentin reduces postoperative pain and opioid demand following thyroid surgery.
Topics: Amines; Analgesics; Analgesics, Opioid; Analysis of Variance; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Preoperative Care; Prospective Studies; Thyroidectomy; Time Factors; Treatment Outcome | 2006 |
Blinded placebo crossover study of gabapentin in primary orthostatic tremor.
Topics: Aged; Amines; Antiparkinson Agents; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dizziness; Double-Blind Method; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurologic Examination; Postural Balance; Quality of Life; Recurrence; Substance Withdrawal Syndrome; Tremor | 2006 |
Cross-sectional evaluation of patient functioning and health-related quality of life in patients with neuropathic pain under standard care conditions.
Topics: Adult; Age Distribution; Aged; Amines; Analgesics; Cohort Studies; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Disability Evaluation; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mental Disorders; Middle Aged; Neuralgia; Pain Clinics; Pain Measurement; Patient Satisfaction; Peripheral Nervous System Diseases; Prospective Studies; Quality of Life; Spain; Treatment Outcome | 2007 |
Comparative study on the bioequivalence of two different gabapentin formulations. A randomised, two-period, two-sequence, crossover clinical trial in healthy volunteers.
Topics: Adolescent; Adult; Amines; Anticonvulsants; Area Under Curve; Capsules; Chemistry, Pharmaceutical; Cross-Over Studies; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Therapeutic Equivalency | 2006 |
The use of gabapentin for post-operative and post-traumatic pain in thoracic surgery patients.
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain, Intractable; Pain, Postoperative; Paresthesia; Patient Satisfaction; Prospective Studies; Thoracic Injuries; Thoracic Surgery, Video-Assisted; Thoracotomy; Treatment Outcome; Wounds, Nonpenetrating | 2006 |
Gabapentin attenuates the pressor response to direct laryngoscopy and tracheal intubation.
Topics: Adult; Amines; Anesthetics, Intravenous; Blood Pressure; Cardiovascular Agents; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Humans; Hysterectomy; Intubation, Intratracheal; Laryngoscopy; Middle Aged; Preanesthetic Medication; Propofol | 2006 |
A double-blind, randomized, placebo-controlled, prophylaxis study of adjunctive gabapentin for bipolar disorder.
Topics: Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Longitudinal Studies; Male; Middle Aged; Pilot Projects; Placebos; Psychiatric Status Rating Scales; Treatment Outcome | 2006 |
Effect of gabapentin on the sensation and impact of tinnitus.
Topics: Adolescent; Adult; Aged; Amines; Audiometry; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Loudness Perception; Male; Middle Aged; Prospective Studies; Reference Values; Risk Assessment; Sensation; Severity of Illness Index; Single-Blind Method; Tinnitus; Treatment Outcome | 2006 |
Pregabalin exerts oppositional effects on different inhibitory circuits in human motor cortex: a double-blind, placebo-controlled transcranial magnetic stimulation study.
Topics: Adult; Amines; Anticonvulsants; Calcium Channels; Cyclohexanecarboxylic Acids; Double-Blind Method; Evoked Potentials, Motor; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Motor Cortex; Neural Inhibition; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Placebos; Pregabalin; Receptors, GABA-B; Recruitment, Neurophysiological; Tiagabine; Transcranial Magnetic Stimulation | 2006 |
Much improved outcome with gabapentin-divalproex combination in adults with bipolar disorders and developmental disabilities.
Topics: Adolescent; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Developmental Disabilities; Drug Combinations; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid | 2006 |
Randomized, placebo-controlled trial of baclofen and gabapentin for the treatment of methamphetamine dependence.
Topics: Adult; Amines; Anti-Anxiety Agents; Baclofen; Central Nervous System Stimulants; Cyclohexanecarboxylic Acids; Demography; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Methamphetamine; Psychology; Substance-Related Disorders; Surveys and Questionnaires | 2006 |
Cost-effectiveness of duloxetine versus routine treatment for U.S. patients with diabetic peripheral neuropathic pain.
Topics: Adrenergic Uptake Inhibitors; Aged; Amines; Amitriptyline; Analgesia; Analgesics; Brain; Cohort Studies; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Cyclohexanols; Diabetic Neuropathies; Double-Blind Method; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Norepinephrine; Pain Measurement; Pain Threshold; Placebo Effect; Serotonin; Thiophenes; Treatment Outcome; United States; Venlafaxine Hydrochloride | 2006 |
Psychometric properties of the MOS (Medical Outcomes Study) Sleep Scale in patients with neuropathic pain.
Topics: Adult; Aged; Amines; Analgesics; Anxiety; Cyclohexanecarboxylic Acids; Depression; Disability Evaluation; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuropsychological Tests; Pain Measurement; Pain, Intractable; Peripheral Nervous System Diseases; Predictive Value of Tests; Prospective Studies; Psychometrics; Sleep Wake Disorders | 2007 |
Multiple dose gabapentin attenuates cutaneous pain and central sensitisation but not muscle pain in healthy volunteers.
Topics: Adult; Amines; Analgesics; Central Nervous System; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Male; Muscle, Skeletal; Pain Measurement; Pain Threshold; Reference Values; Skin; Treatment Outcome | 2006 |
Gabapentin reduces cardiovascular responses to laryngoscopy and tracheal intubation.
Topics: Administration, Oral; Adult; Amines; Anesthesia; Blood Pressure; Cardiovascular Surgical Procedures; Cardiovascular System; Cyclohexanecarboxylic Acids; Double-Blind Method; Elective Surgical Procedures; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Humans; Intubation, Intratracheal; Laryngoscopy; Male; Middle Aged; Treatment Outcome | 2006 |
Gabapentin, estrogen, and placebo for treating hot flushes: a randomized controlled trial.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Estrogens; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Middle Aged; Treatment Outcome | 2006 |
Application of Gabapentin in Thai women with menopausal syndrome.
Topics: Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Thailand | 2005 |
The effect of gabapentin on post-operative pain following tonsillectomy in adults.
Topics: Adolescent; Adult; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lactones; Male; Meperidine; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Sulfones; Tonsillectomy | 2006 |
Treatment of partial seizures with gabapentin: double-blind, placebo-controlled, parallel-group study.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Japan; Male; Middle Aged; Treatment Outcome | 2006 |
CHF3381, a N-methyl-D-aspartate receptor antagonist and monoamine oxidase-A inhibitor, attenuates secondary hyperalgesia in a human pain model.
Topics: Adult; Amines; Analgesics; Capsaicin; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glycine; Humans; Hyperalgesia; Indans; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pain; Pain Measurement; Receptors, N-Methyl-D-Aspartate | 2006 |
The effect of gabapentin in earlier stage of reflex sympathetic dystrophy.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Exercise Therapy; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain Measurement; Reflex Sympathetic Dystrophy; Treatment Outcome | 2007 |
Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Delirium; Feasibility Studies; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurosurgical Procedures; Pain Measurement; Pain, Postoperative; Pilot Projects; Placebo Effect; Premedication; Spine; Treatment Outcome | 2006 |
Clinical efficacy of gabapentin versus tiagabine for reducing cocaine use among cocaine dependent methadone-treated patients.
Topics: Adult; Amines; Anti-Anxiety Agents; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Methadone; Narcotics; Nipecotic Acids; Tiagabine; Treatment Outcome | 2007 |
Gabapentin versus nortriptyline in post-herpetic neuralgia patients: a randomized, double-blind clinical trial--the GONIP Trial.
Topics: Aged; Amines; Analgesics; Capsules; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypotension, Orthostatic; Male; Middle Aged; Neuralgia, Postherpetic; Nortriptyline; Pain Measurement; Time Factors; Treatment Outcome; Urinary Retention; Xerostomia | 2006 |
Pharmacokinetics and bioequivalence evaluation of two gabapentin preparations after a single oral dose in healthy Korean volunteers.
Topics: Administration, Oral; Adult; Algorithms; Amines; Anticonvulsants; Area Under Curve; Asian People; Biological Availability; Capsules; Chromatography, High Pressure Liquid; Cross-Over Studies; Cyclohexanecarboxylic Acids; Drug Compounding; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Male; Metabolic Clearance Rate; Therapeutic Equivalency; Time Factors | 2006 |
Analgesic action of gabapentin on chronic pain in the masticatory muscles: a randomized controlled trial.
Topics: Adolescent; Adult; Amines; Analgesics; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Facial Pain; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Masticatory Muscles; Middle Aged; Pain Measurement; Temporomandibular Joint Dysfunction Syndrome; Treatment Outcome | 2007 |
A single preoperative dose of gabapentin (800 milligrams) does not augment postoperative analgesia in patients given interscalene brachial plexus blocks for arthroscopic shoulder surgery.
Topics: Adult; Amines; Arthroscopy; Brachial Plexus; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nerve Block; Pain Measurement; Pain, Postoperative; Preoperative Care; Shoulder | 2006 |
Gabapentin in patients with the pruritus of cholestasis: a double-blind, randomized, placebo-controlled trial.
Topics: Adult; Amines; Analgesics; Cholestasis; Chronic Disease; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Liver Diseases; Middle Aged; Pain Measurement; Pruritus | 2006 |
A randomized study of the effects of gabapentin on postamputation pain.
Topics: Aged; Amines; Amputation Stumps; Amputation, Surgical; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Leg; Male; Middle Aged; Pain; Pain Threshold; Phantom Limb; Time Factors | 2006 |
[Comparison of efficacy of gabapentin and amitriptyline in the management of peripheral neuropathic pain].
Topics: Amines; Amitriptyline; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Patient Satisfaction; Treatment Outcome | 2006 |
Treatment of tinnitus with gabapentin: a pilot study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Auditory Threshold; Cyclohexanecarboxylic Acids; Disability Evaluation; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Hearing Loss, Bilateral; Hearing Loss, Unilateral; Humans; Male; Middle Aged; Mood Disorders; Pilot Projects; Quality of Life; Severity of Illness Index; Surveys and Questionnaires; Tinnitus | 2007 |
Phase III trial of gabapentin alone or in conjunction with an antidepressant in the management of hot flashes in women who have inadequate control with an antidepressant alone: NCCTG N03C5.
Topics: Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Antidepressive Agents; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Middle Aged; Treatment Outcome | 2007 |
[Efficacy, safety and effect on the quality of life of gabapentin in adult epilepsy--results of a prospective open-label quasi naturalistic Hungarian multicenter study (phase human-IV)].
Topics: Adult; Aged; Ambulatory Care Facilities; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hungary; Male; Middle Aged; Prospective Studies; Quality of Life; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome | 2006 |
Gabapentin's acute effect on mood profile -- a controlled study on patients with alcohol withdrawal.
Topics: Adult; Affect; Alcohol-Induced Disorders; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2007 |
Premedication with gabapentin: the effect on tourniquet pain and quality of intravenous regional anesthesia.
Topics: Adult; Amines; Analgesics; Anesthesia, Conduction; Anesthesia, Intravenous; Cyclohexanecarboxylic Acids; Elective Surgical Procedures; Female; Gabapentin; gamma-Aminobutyric Acid; Hand; Humans; Male; Middle Aged; Pain; Patient Selection; Placebos; Premedication | 2007 |
A combination of gabapentin and local anaesthetics attenuates acute and late pain after abdominal hysterectomy.
Topics: Administration, Oral; Adult; Amides; Amines; Analgesics, Opioid; Anesthetics, Combined; Anesthetics, Local; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Injections, Subcutaneous; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studies; Ropivacaine; Statistics, Nonparametric | 2007 |
Gabapentin does not reduce smoked cocaine self-administration: employment of a novel self-administration procedure.
Topics: Adult; Affect; Ambulatory Care; Amines; Arousal; Blood Pressure; Choice Behavior; Cocaine; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Euphoria; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Humans; Male; Motivation; Patient Admission; Self Administration; Token Economy; Treatment Failure | 2007 |
[The tebantin use in the complex therapy of pain syndrome during the mixed forms of alcoholic polyneuropathy].
Topics: Alcoholic Neuropathy; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain; Syndrome; Treatment Outcome | 2006 |
A double-blind evaluation of gabapentin on alcohol effects and drinking in a clinical laboratory paradigm.
Topics: Adult; Aged; Alcohol-Related Disorders; Alcoholism; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Ethanol; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Patient Compliance; Substance Withdrawal Syndrome | 2007 |
The post-operative analgesic effects of a combination of gabapentin and paracetamol in patients undergoing abdominal hysterectomy: a randomized clinical trial.
Topics: Acetaminophen; Adult; Algorithms; Amines; Analgesics; Analgesics, Opioid; Anesthetics, Combined; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Patient Satisfaction | 2007 |
Benzodiazepines and GABAergics in treating severe disabling tinnitus of predominantly cochlear origin.
Topics: Adult; Amines; Benzodiazepines; Clonazepam; Cochlear Diseases; Cyclohexanecarboxylic Acids; Disability Evaluation; Drug Therapy, Combination; Female; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Severity of Illness Index; Single-Blind Method; Tinnitus; Treatment Failure | 2006 |
Congenital nystagmus: randomized, controlled, double-masked trial of memantine/gabapentin.
Topics: Adult; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Double-Blind Method; Excitatory Amino Acid Antagonists; Eye Movements; Female; Fovea Centralis; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Memantine; Middle Aged; Nystagmus, Congenital; Visual Acuity | 2007 |
Gabapentin activates spinal noradrenergic activity in rats and humans and reduces hypersensitivity after surgery.
Topics: Adrenergic alpha-Antagonists; Amines; Analgesics; Analgesics, Opioid; Animals; Bee Venoms; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Idazoxan; Male; Morphine; Norepinephrine; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerve Roots; Time Factors | 2007 |
The effect of MDR1 G2677T/A polymorphism on pharmacokinetics of gabapentin in healthy Korean subjects.
Topics: Adenine; Administration, Oral; Adult; Amines; Anticonvulsants; Area Under Curve; Asian People; ATP Binding Cassette Transporter, Subfamily B, Member 1; Capsules; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Exons; Gabapentin; gamma-Aminobutyric Acid; Genotype; Guanine; Half-Life; Humans; Korea; Male; Metabolic Clearance Rate; Phenotype; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Reference Values; Reproducibility of Results; Thymine | 2007 |
Topiramate effects on the EEG and alertness in healthy volunteers: a different profile of antiepileptic drug neurotoxicity.
Topics: Adult; Amines; Anticonvulsants; Arousal; Association Learning; Cyclohexanecarboxylic Acids; Double-Blind Method; Electroencephalography; Female; Fourier Analysis; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuropsychological Tests; Reaction Time; Topiramate | 2007 |
Gabapentin for smoking cessation: a preliminary investigation of efficacy.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Smoking; Smoking Cessation | 2007 |
Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Severity of Illness Index; Treatment Outcome | 2007 |
Validated LC-MS/MS method for quantification of gabapentin in human plasma: application to pharmacokinetic and bioequivalence studies in Korean volunteers.
Topics: Administration, Oral; Amines; Anticonvulsants; Atmospheric Pressure; Cross-Over Studies; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Reference Standards; Sensitivity and Specificity; Tandem Mass Spectrometry; Therapeutic Equivalency | 2007 |
Relief of idiopathic subjective tinnitus: is gabapentin effective?
Topics: Adolescent; Adult; Aged; Amines; Calcium Channel Blockers; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Tinnitus; Treatment Outcome | 2007 |
Effectiveness of gabapentin in the treatment of chronic post-thoracotomy pain.
Topics: Adult; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Naproxen; Pain Measurement; Pain, Postoperative; Patient Compliance; Prospective Studies; Thoracotomy; Treatment Outcome | 2007 |
The efficiency of gabapentin therapy in patients with lumbar spinal stenosis.
Topics: Adult; Aged; Amines; Analgesics; Back Pain; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lumbar Vertebrae; Male; Middle Aged; Pain Measurement; Pilot Projects; Spinal Stenosis; Walking | 2007 |
Use of gabapentin for perioperative pain control -- a meta-analysis.
Topics: Adult; Amines; Analgesics; Confidence Intervals; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; MEDLINE; Middle Aged; Movement; Pain Measurement; Pain, Postoperative; Retrospective Studies; Sensitivity and Specificity; Time Factors | 2007 |
Double-blind crossover trial of gabapentin in SPG4-linked hereditary spastic paraplegia.
Topics: Adenosine Triphosphatases; Adult; Aged; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Spastic Paraplegia, Hereditary; Spastin; Statistics, Nonparametric | 2007 |
The use of gabapentin in chronic cluster headache patients refractory to first-line therapy.
Topics: Adolescent; Adult; Aged; Amines; Analgesics; Cluster Headache; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Retrospective Studies; Treatment Outcome | 2007 |
Self-reported sleep, sleepiness, and repeated alcohol withdrawals: a randomized, double blind, controlled comparison of lorazepam vs gabapentin.
Topics: Adult; Aged; Alcoholism; Amines; Cyclohexanecarboxylic Acids; Disorders of Excessive Somnolence; Double-Blind Method; Ethanol; Female; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Lorazepam; Male; Middle Aged; Severity of Illness Index; Substance Withdrawal Syndrome; Surveys and Questionnaires | 2007 |
Gabapentin improves sleep in the presence of alcohol.
Topics: Adult; Alcoholic Intoxication; Amines; Anti-Anxiety Agents; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Polysomnography; Severity of Illness Index; Sleep Stages; Sleep Wake Disorders | 2005 |
Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing.
Topics: Amines; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Autonomic Nervous System Diseases; Cohort Studies; Conjunctiva; Cyclohexanecarboxylic Acids; Fructose; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypothalamus, Posterior; Indomethacin; Lamotrigine; Lidocaine; Magnetic Resonance Imaging; Oxygen; Pain Measurement; Phenotype; Prospective Studies; SUNCT Syndrome; Tears; Topiramate; Triazines | 2007 |
Gabapentin and an opioid combination versus opioid alone for the management of neuropathic cancer pain: a randomized open trial.
Topics: Adult; Aged; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasms; Neuralgia; Treatment Outcome | 2007 |
Pre-emptive gabapentin significantly reduces postoperative pain and morphine demand following lower extremity orthopaedic surgery.
Topics: Adult; Amines; Analgesics; Arthroscopy; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Utilization; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Knee; Male; Morphine; Pain Measurement; Pain, Postoperative; Preoperative Care | 2007 |
Gabapentin: a promising drug for the treatment of uremic pruritus.
Topics: Adult; Aged; Aged, 80 and over; Amines; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pruritus; Renal Dialysis; Uremia | 2007 |
Low-dose gabapentin in treatment of high-altitude headache.
Topics: Adolescent; Adult; Altitude Sickness; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Male; Middle Aged; Pilot Projects | 2007 |
Effect of gabapentin on oculomotor control and parkinsonism in patients with progressive supranuclear palsy.
Topics: Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Eye Movements; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Parkinson Disease; Severity of Illness Index; Supranuclear Palsy, Progressive | 2007 |
Chronobiological characteristics of postoperative pain: diurnal variation of both static and dynamic pain and effects of analgesic therapy.
Topics: Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Circadian Rhythm; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Lactones; Morphine; Pain Measurement; Pain, Postoperative; Single-Blind Method; Sulfones; Time Factors | 2007 |
Efficacy of gabapentin in the management of chemotherapy-induced peripheral neuropathy: a phase 3 randomized, double-blind, placebo-controlled, crossover trial (N00C3).
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Antineoplastic Agents; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Placebo Effect | 2007 |
Cost-effectiveness analysis of pregabalin versus gabapentin in the management of neuropathic pain due to diabetic polyneuropathy or post-herpetic neuralgia.
Topics: Amines; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Pain; Pain Measurement; Placebos; Pregabalin | 2007 |
The analgesic effects of preemptive gabapentin in patients undergoing surgery for brachial plexus injury--a preliminary study.
Topics: Adolescent; Adult; Amines; Analgesics; Brachial Plexus; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Movement; Pain Measurement; Pain, Postoperative; Preoperative Care | 2007 |
The preoperative use of gabapentin, dexamethasone, and their combination in varicocele surgery: a randomized controlled trial.
Topics: Adult; Amines; Analgesics; Analgesics, Opioid; Blood Pressure; Cyclohexanecarboxylic Acids; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Heart Rate; Humans; Intubation, Intratracheal; Male; Oxygen; Pain Measurement; Pain, Postoperative; Piperidines; Postoperative Nausea and Vomiting; Preoperative Care; Remifentanil; Varicocele | 2007 |
A randomised controlled trial examining the longer-term outcomes of standard versus new antiepileptic drugs. The SANAD trial.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Health Status Indicators; Humans; Lamotrigine; Male; Oxcarbazepine; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2007 |
An evaluation of the efficacy of gabapentin for prevention of catheter-related bladder discomfort: a prospective, randomized, placebo-controlled, double-blind study.
Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Prospective Studies; Severity of Illness Index; Urinary Bladder; Urinary Catheterization | 2007 |
Gabapentin effectiveness on the sensation of subjective idiopathic tinnitus: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Amines; Cyclohexanecarboxylic Acids; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pilot Projects; Tinnitus; Treatment Failure | 2008 |
Gabapentin for prevention of hypobaric hypoxia-induced headache: randomized double-blind clinical trial.
Topics: Adolescent; Adult; Aged; Altitude Sickness; Amines; Cyclohexanecarboxylic Acids; Disorders of Excessive Somnolence; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Hypoxia; Male; Middle Aged | 2008 |
Comparison of the effectiveness of amitriptyline and gabapentin on chronic neuropathic pain in persons with spinal cord injury.
Topics: Adult; Aged; Amines; Amitriptyline; Analgesics; Analysis of Variance; Antidepressive Agents, Tricyclic; Cross-Over Studies; Cyclohexanecarboxylic Acids; Diphenhydramine; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Histamine H1 Antagonists; Humans; Male; Middle Aged; Mononeuropathies; Pain; Pain Measurement; Spinal Cord Injuries | 2007 |
Gabapentin reduces alcohol consumption and craving: a randomized, double-blind, placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Alcohol Deterrents; Alcoholism; Ambulatory Care; Amines; Blood-Brain Barrier; Brazil; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Ethanol; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Male; Middle Aged; Obsessive-Compulsive Disorder; Prevalence; Severity of Illness Index; Substance Withdrawal Syndrome; Temperance | 2007 |
[Effect of preoperative 900 and 1200 mg single oral dose of gabapentin on postoperative pain relief and tramadol consumption in open cholecystectomy surgery].
Topics: Administration, Oral; Adult; Aged; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cholecystectomy; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusions, Intravenous; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Preoperative Care; Prospective Studies; Tramadol; Treatment Outcome | 2007 |
Pharmacotherapy to prevent PTSD: Results from a randomized controlled proof-of-concept trial in physically injured patients.
Topics: Adolescent; Adult; Amines; Anti-Anxiety Agents; California; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Placebos; Propranolol; Stress Disorders, Post-Traumatic; Vasodilator Agents; Wounds and Injuries | 2007 |
The median effective dose of preemptive gabapentin on postoperative morphine consumption after posterior lumbar spinal fusion.
Topics: Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Lumbar Vertebrae; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studies; Spinal Fusion; Time Factors; Treatment Outcome | 2008 |
Preoperative gabapentin: the effect on ropivacaine subarachnoid block and hemodynamics.
Topics: Administration, Oral; Aged; Amides; Amines; Analgesics; Anesthetics, Local; Blood Pressure; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Humans; Middle Aged; Nerve Block; Papilloma; Preoperative Care; Ropivacaine; Sensory Thresholds; Subarachnoid Space; Time Factors; Urinary Bladder Neoplasms | 2008 |
Gabapentin supplemented with ropivacain block of trigger points improves pain control and quality of life in trigeminal neuralgia patients when compared with gabapentin alone.
Topics: Acetaminophen; Amides; Amines; Analgesics; Analgesics, Non-Narcotic; Anesthetics, Local; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Quality of Life; Ropivacaine; Treatment Outcome; Trigeminal Neuralgia | 2008 |
Oral gabapentin for the treatment of postoperative pain after photorefractive keratectomy.
Topics: Acetaminophen; Administration, Oral; Adult; Amines; Analgesics; Anti-Bacterial Agents; Cyclohexanecarboxylic Acids; Drug Combinations; Female; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Humans; Lasers, Excimer; Male; Middle Aged; Oxycodone; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Photorefractive Keratectomy; Prospective Studies | 2008 |
Gabapentin in traumatic nerve injury pain: a randomized, double-blind, placebo-controlled, cross-over, multi-center study.
Topics: Adult; Aged; Aged, 80 and over; Amines; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Internationality; Male; Middle Aged; Neuralgia; Pain Measurement; Peripheral Nerve Injuries; Peripheral Nerves; Trauma, Nervous System | 2008 |
Prolonged-release oxycodone enhances the effects of existing gabapentin therapy in painful diabetic neuropathy patients.
Topics: Aged; Amines; Analgesics, Opioid; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Diabetic Neuropathies; Drug Synergism; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Oxycodone; Pain Measurement; Patient Satisfaction; Sleep Wake Disorders; Treatment Outcome | 2008 |
Does gabapentin lead to early symptom improvement in obsessive-compulsive disorder?
Topics: Administration, Oral; Adolescent; Adult; Amines; Analysis of Variance; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Young Adult | 2008 |
Preoperative gabapentin prevents intrathecal morphine-induced pruritus after orthopedic surgery.
Topics: Adult; Amines; Anesthesia, Spinal; Anesthetics, Local; Antipruritics; Bupivacaine; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Lower Extremity; Male; Morphine; Narcotics; Orthopedic Procedures; Premedication; Prospective Studies; Pruritus; Severity of Illness Index; Time Factors; Treatment Outcome | 2008 |
Assessment of the efficacy of gabapentin in carpal tunnel syndrome.
Topics: Adult; Amines; Analgesics; Carpal Tunnel Syndrome; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Patient Satisfaction; Prospective Studies; Severity of Illness Index | 2008 |
A randomized double-blind pilot trial of gabapentin versus placebo to treat alcohol dependence and comorbid insomnia.
Topics: Adult; Alcohol Drinking; Alcoholism; Amines; Antimanic Agents; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Patient Compliance; Pilot Projects; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2008 |
Pharmacokinetics of gabapentin after a single day and at steady state following the administration of gastric-retentive- extended-release and immediate-release tablets: a randomized, open-label, multiple-dose, three-way crossover, exploratory study in hea
Topics: Adult; Amines; Analgesics; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Female; Gabapentin; gamma-Aminobutyric Acid; Gastric Mucosa; Humans; Male; Middle Aged; Tablets | 2008 |
Gabapentin does not reduce post-thoracotomy shoulder pain: a randomized, double-blind placebo-controlled study.
Topics: Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain, Postoperative; Shoulder Pain; Thoracotomy | 2008 |
Identifying subpopulations for subgroup analysis in a longitudinal clinical trial.
Topics: Adult; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Data Interpretation, Statistical; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Linear Models; Longitudinal Studies; Middle Aged; Models, Statistical; Postmenopause | 2008 |
Efficacy of gabapentin in the treatment of SUNCT syndrome.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Iran; Male; Middle Aged; SUNCT Syndrome; Treatment Outcome; Young Adult | 2008 |
Topical gabapentin in the treatment of localized and generalized vulvodynia.
Topics: Administration, Topical; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Treatment Outcome; Vulvar Diseases | 2008 |
Effect of add-on gabapentin on opioid withdrawal symptoms in opium-dependent patients.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Opioid-Related Disorders; Statistics, Nonparametric; Substance Withdrawal Syndrome; Treatment Outcome | 2008 |
Effects of gabapentin on early postoperative pain, nausea and vomiting in laparoscopic surgery for assisted reproductive technologies.
Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Laparoscopy; Middle Aged; Pain, Postoperative; Postoperative Nausea and Vomiting; Reproductive Techniques, Assisted | 2008 |
Clinical pharmacokinetics of XP13512, a novel transported prodrug of gabapentin.
Topics: Adult; Aged; Amines; Area Under Curve; Biological Availability; Capsules; Carbamates; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Headache; Humans; Male; Middle Aged; Molecular Structure; Molecular Weight; Prodrugs; Sleep Wake Disorders; Young Adult | 2008 |
Effect of oral gabapentin on the intraocular pressure and haemodynamic responses induced by tracheal intubation.
Topics: Administration, Oral; Adult; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hemodynamics; Humans; Intraocular Pressure; Intubation, Intratracheal; Male | 2008 |
Proof-of-concept human laboratory study for protracted abstinence in alcohol dependence: effects of gabapentin.
Topics: Adult; Affect; Alcohol Deterrents; Alcohol Withdrawal Delirium; Alcoholism; Amines; Arousal; Cues; Cyclohexanecarboxylic Acids; Electromyography; Female; Gabapentin; Galvanic Skin Response; gamma-Aminobutyric Acid; Heart Rate; Humans; Male; Middle Aged; Motivation; Pain Measurement; Secondary Prevention; Sleep; Temperance; Treatment Outcome | 2009 |
Gabapentin attenuates late but not early postoperative pain after thyroidectomy with superficial cervical plexus block.
Topics: Adolescent; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Deglutition; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nerve Block; Pain Measurement; Pain, Postoperative; Placebos; Thyroidectomy; Time Factors | 2008 |
Efficient assessment of neuropathic pain drugs in patients with small fiber sensory neuropathies.
Topics: Adolescent; Adult; Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Diphenhydramine; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Single-Blind Method; Sleep Wake Disorders; Tramadol; Young Adult | 2009 |
High incidence of oral dysesthesias on a trial of gefitinib, Paclitaxel, and concurrent external beam radiation for locally advanced head and neck cancers.
Topics: Adult; Aged; Amines; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Gefitinib; Head and Neck Neoplasms; Humans; Incidence; Male; Middle Aged; Neoplasm Staging; Paclitaxel; Paresthesia; Prognosis; Quinazolines; Radiation Injuries; Radiotherapy; Stomatitis | 2008 |
The effectiveness of gabapentin on post-tonsillectomy pain control.
Topics: Adolescent; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain Measurement; Pain, Postoperative; Premedication; Tonsillectomy; Treatment Outcome; Young Adult | 2009 |
A phase III randomized, double-blind, placebo-controlled trial of gabapentin in the management of hot flashes in men (N00CB).
Topics: Aged; Aged, 80 and over; Amines; Androgen Antagonists; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Male; Middle Aged; Placebos; Prostatic Neoplasms | 2009 |
A randomized, double-blind, controlled trial of perioperative administration of gabapentin, meloxicam and their combination for spontaneous and movement-evoked pain after ambulatory laparoscopic cholecystectomy.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Meloxicam; Middle Aged; Movement; Oxygen Inhalation Therapy; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Spirometry; Thiazines; Thiazoles; Treatment Outcome; Young Adult | 2009 |
Spinocerebellar ataxia type 6 (SCA6): clinical pilot trial with gabapentin.
Topics: Adult; Aged; Amines; Brain; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuropsychological Tests; Pilot Projects; Postural Balance; Spinocerebellar Ataxias | 2009 |
Gabapentin extended release for the treatment of painful diabetic peripheral neuropathy: efficacy and tolerability in a double-blind, randomized, controlled clinical trial.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Tablets | 2009 |
Randomized, double-blind, placebo-controlled study of XP13512/GSK1838262 in patients with RLS.
Topics: Adult; Amines; Anti-Anxiety Agents; Carbamates; Central Nervous System; Cyclohexanecarboxylic Acids; Disorders of Excessive Somnolence; Dizziness; Double-Blind Method; Drug Administration Schedule; Endpoint Determination; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Placebos; Restless Legs Syndrome; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2009 |
A randomized, placebo-controlled trial of oxycodone and of gabapentin for acute pain in herpes zoster.
Topics: Acute Disease; Aged; Amines; Analgesics, Opioid; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Evidence-Based Medicine; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; New York; Oxycodone; Pain; Placebo Effect; Texas; Treatment Outcome | 2009 |
Gabapentin and uremic pruritus in hemodialysis patients.
Topics: Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pruritus; Renal Dialysis; Uremia | 2009 |
Non-hormonal treatment of hot flushes in breast cancer survivors: gabapentin vs. vitamin E.
Topics: Adult; Aged; Amines; Breast Neoplasms; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Middle Aged; Quality of Life; Sleep; Surveys and Questionnaires; Survivors; Tamoxifen; Vitamin E | 2009 |
The effects of gabapentin on acute and chronic pain after inguinal herniorrhaphy.
Topics: Adult; Amines; Analgesics; Anesthesia, Spinal; Chronic Disease; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Hernia, Inguinal; Humans; Male; Pain Measurement; Pain, Postoperative; Preoperative Care; Prospective Studies; Tramadol; Treatment Outcome; Young Adult | 2009 |
Adequacy assessment of oxycodone/paracetamol (acetaminophen) in multimodal chronic pain : a prospective observational study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Combinations; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Male; Middle Aged; Osteoarthritis; Oxycodone; Pain; Pain Measurement; Peripheral Nervous System Diseases; Prospective Studies | 2009 |
A double-blind trial of gabapentin versus lorazepam in the treatment of alcohol withdrawal.
Topics: Adult; Alcohol Drinking; Amines; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Lorazepam; Male; Psychiatric Status Rating Scales; Recurrence; Substance Withdrawal Syndrome; Treatment Outcome | 2009 |
Adding gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty.
Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Arthroplasty, Replacement, Hip; Chronic Disease; Cyclohexanecarboxylic Acids; Data Interpretation, Statistical; Double-Blind Method; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Pruritus; Sample Size | 2009 |
Attenuation of hemodynamic responses following laryngoscopy and tracheal intubation -- comparative assessment of clonidine and gabapentin premedication.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Amines; Blood Pressure; Clonidine; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Humans; Intubation, Intratracheal; Laryngoscopy; Male; Middle Aged; Time Factors; Young Adult | 2009 |
Assessment of pain quality in a clinical trial of gabapentin extended release for postherpetic neuralgia.
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia, Postherpetic; Pain Measurement; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome | 2009 |
Efficacy of a combination of flumazenil and gabapentin in the treatment of alcohol dependence: relationship to alcohol withdrawal symptoms.
Topics: Administration, Oral; Adult; Alcohol Drinking; Alcoholism; Amines; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Flumazenil; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusions, Intravenous; Logistic Models; Male; Medication Adherence; Middle Aged; Patient Selection; Sleep; Substance Withdrawal Syndrome; Temperance; Time Factors; Treatment Outcome | 2009 |
Acupuncture in acute herpes zoster pain therapy (ACUZoster) - design and protocol of a randomised controlled trial.
Topics: Acupuncture Therapy; Acute Disease; Adult; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Herpesvirus 3, Human; Humans; Pain; Pain Management; Pain Measurement; Placebos; Severity of Illness Index; Surveys and Questionnaires | 2009 |
Effects of gabapentin on sleep in menopausal women with hot flashes as measured by a Pittsburgh Sleep Quality Index factor scoring model.
Topics: Adult; Amines; Analgesics; Cohort Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Middle Aged; Patient Satisfaction; Quality of Life; Sleep; Treatment Outcome; Women's Health | 2009 |
The analgesic effect of gabapentin as a prophylactic anticonvulsant drug on postcraniotomy pain: a prospective randomized study.
Topics: Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Intravenous; Anticonvulsants; Craniotomy; Cyclohexanecarboxylic Acids; Dizziness; Drug Administration Schedule; Fatigue; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intubation, Intratracheal; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Phenytoin; Piperidines; Preanesthetic Medication; Propofol; Prospective Studies; Remifentanil; Sleep; Supratentorial Neoplasms; Time Factors; Treatment Outcome | 2009 |
Multimodal analgesia with gabapentin, ketamine and dexamethasone in combination with paracetamol and ketorolac after hip arthroplasty: a preliminary study.
Topics: Acetaminophen; Aged; Amines; Analgesia; Analgesics; Arthroplasty, Replacement, Hip; Cyclohexanecarboxylic Acids; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Ketorolac; Male; Pain Measurement; Pain, Postoperative; Time Factors; Treatment Outcome | 2010 |
Acquired pendular nystagmus in multiple sclerosis: an examiner-blind cross-over treatment study of memantine and gabapentin.
Topics: Adult; Amines; Brain Stem; Clinical Protocols; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Eye Movements; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Memantine; Middle Aged; Multiple Sclerosis; Neural Pathways; Nystagmus, Pathologic; Prospective Studies; Single-Blind Method; Treatment Outcome; Young Adult | 2010 |
Nortriptyline and gabapentin, alone and in combination for neuropathic pain: a double-blind, randomised controlled crossover trial.
Topics: Administration, Oral; Aged; Amines; Analgesics; Antidepressive Agents, Tricyclic; Canada; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Least-Squares Analysis; Linear Models; Male; Middle Aged; Neuralgia; Nortriptyline; Pain Measurement; Treatment Outcome | 2009 |
Efficacy of gabapentin versus diclofenac in the treatment of chest pain and paresthesia in patients with sternotomy.
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chest Pain; Cyclohexanecarboxylic Acids; Diclofenac; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Paresthesia; Severity of Illness Index; Sternotomy; Treatment Outcome | 2009 |
A comparison of gabapentin and ketamine in acute and chronic pain after hysterectomy.
Topics: Acute Disease; Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Chronic Disease; Cyclohexanecarboxylic Acids; Double-Blind Method; Elective Surgical Procedures; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Infusions, Intravenous; Ketamine; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Prospective Studies; Recovery of Function; Time Factors; Treatment Outcome | 2009 |
The efficacy of gabapentin in migraine prophylaxis: an observational open label study.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Migraine Disorders | 2009 |
Effect of preoperative gabapentin on postoperative pain and tramadol consumption after minilap open cholecystectomy: a randomized double-blind, placebo-controlled trial.
Topics: Adult; Amines; Analgesics; Analgesics, Opioid; Case-Control Studies; Cholecystectomy; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Preoperative Care; Tramadol | 2010 |
A controlled trial of flumazenil and gabapentin for initial treatment of methylamphetamine dependence.
Topics: Adolescent; Adult; Amines; Amphetamine-Related Disorders; Anticonvulsants; Behavior, Addictive; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Flumazenil; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Patient Compliance | 2011 |
Effects of preoperative gabapentin on postoperative nausea and vomiting after open cholecystectomy: a prospective randomized double-blind placebo-controlled study.
Topics: Adult; Aged; Amines; Analgesics; Cholecystectomy; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain, Postoperative; Placebos; Postoperative Nausea and Vomiting; Preoperative Care | 2010 |
Gabapentin monotherapy in patients with chronic radiculopathy: the efficacy and impact on life quality.
Topics: Administration, Oral; Adult; Amines; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Depression; Disability Evaluation; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Male; Middle Aged; Pain Measurement; Quality of Life; Radiculopathy; Treatment Outcome | 2009 |
Gabapentin vs. low-dose transdermal estradiol for treating post-menopausal women with moderate to very severe hot flushes.
Topics: Administration, Cutaneous; Amines; Cyclohexanecarboxylic Acids; Estradiol; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Middle Aged; Postmenopause; Prospective Studies | 2010 |
Gabapentin in the prophylaxis of cluster headache: an observational open label study.
Topics: Adult; Amines; Analgesics; Anticonvulsants; Cluster Headache; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 2009 |
Effects of single-dose gabapentin on postoperative pain and morphine consumption after cardiac surgery.
Topics: Adult; Amines; Coronary Artery Bypass; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Morphine; Pain, Postoperative; Postoperative Nausea and Vomiting | 2010 |
A prospective open-label trial of gabapentin as an adjuvant analgesic with opioids for Japanese patients with neuropathic cancer pain.
Topics: Adult; Aged; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Japan; Male; Middle Aged; Neoplasms; Pain; Pain Measurement; Palliative Care; Prospective Studies | 2010 |
Gabapentin for smoking cessation.
Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Smoking Cessation | 2010 |
The effect of food with varying fat content on the clinical pharmacokinetics of gabapentin after oral administration of gabapentin enacarbil.
Topics: Adult; Amines; Anticonvulsants; Area Under Curve; Biological Availability; Carbamates; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dietary Fats; Female; Food-Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Prodrugs; Young Adult | 2010 |
Gabapentin improves cold-pressor pain responses in methadone-maintained patients.
Topics: Adult; Amines; Analgesics, Non-Narcotic; Cold Temperature; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Male; Methadone; Middle Aged; Narcotics; Opioid-Related Disorders; Pain Measurement; Pain Threshold; Patient Compliance; Pressure | 2010 |
Low-dose gabapentin as useful adjuvant to opioids for neuropathic cancer pain when combined with low-dose imipramine.
Topics: Aged; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Imipramine; Male; Middle Aged; Neoplasms; Pain; Pain Measurement; Peripheral Nervous System Diseases | 2010 |
Gabapentin does not reduce preoperative anxiety when given prior to total hip arthroplasty.
Topics: Aged; Amines; Anti-Anxiety Agents; Anxiety; Arthroplasty, Replacement, Hip; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Placebos; Preoperative Period; Treatment Outcome | 2010 |
Clinical evaluation of perioperative administration of gabapentin as an adjunct for postoperative analgesia in dogs undergoing amputation of a forelimb.
Topics: Amines; Amputation, Surgical; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dog Diseases; Dogs; Forelimb; Gabapentin; gamma-Aminobutyric Acid; Pain, Postoperative; Perioperative Care | 2010 |
Gabapentin use in pediatric spinal fusion patients: a randomized, double-blind, controlled trial.
Topics: Acute Disease; Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Child; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Scoliosis; Spinal Fusion; Treatment Outcome | 2010 |
Crossover trial of gabapentin and memantine as treatment for acquired nystagmus.
Topics: Adult; Amines; Cross-Over Studies; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Eye Movements; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Memantine; Middle Aged; Nystagmus, Pathologic | 2010 |
Evaluation of efficacy of the perioperative administration of Venlafaxine or gabapentin on acute and chronic postmastectomy pain.
Topics: Acute Disease; Adult; Amines; Analgesics; Breast Neoplasms; Chronic Disease; Cyclohexanecarboxylic Acids; Cyclohexanols; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mastectomy, Radical; Mastectomy, Segmental; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Perioperative Care; Statistics, Nonparametric; Treatment Outcome; Venlafaxine Hydrochloride | 2010 |
Gabapentin premedication decreases the hemodynamic response to skull pin insertion in patients undergoing craniotomy.
Topics: Adolescent; Adult; Amines; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Local; Blood Pressure; Bone Nails; Brain Neoplasms; Craniotomy; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Humans; Intraoperative Period; Lidocaine; Male; Methyl Ethers; Middle Aged; Preanesthetic Medication; Prospective Studies; Respiratory Function Tests; Sevoflurane; Skull; Young Adult | 2011 |
Pharmacokinetics of gabapentin in a novel gastric-retentive extended-release formulation: comparison with an immediate-release formulation and effect of dose escalation and food.
Topics: Adult; Amines; Analgesics, Non-Narcotic; Anticonvulsants; Biological Availability; Calcium Channel Blockers; Cross-Over Studies; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Dietary Fats; Dose-Response Relationship, Drug; Female; Food-Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Gastric Emptying; Gastric Mucosa; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Young Adult | 2011 |
A fMRI evaluation of lamotrigine for the treatment of trigeminal neuropathic pain: pilot study.
Topics: Adult; Amines; Anticonvulsants; Brain; Cold Temperature; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Middle Aged; Pain; Pain Measurement; Placebos; Psychiatric Status Rating Scales; Touch; Treatment Outcome; Triazines; Trigeminal Neuralgia | 2010 |
Effect of gabapentin on pain after cardiac surgery: a randomised, double-blind, placebo-controlled trial.
Topics: Adult; Aged; Amines; Analgesics; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain, Postoperative; Placebos | 2010 |
Combination of alpha lipoic acid and gabapentin, its efficacy in the treatment of Burning Mouth Syndrome: a randomized, double-blind, placebo controlled trial.
Topics: Amines; Burning Mouth Syndrome; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Thioctic Acid | 2011 |
Comparison of the efficacy and safety of tramadol/acetaminophen combination therapy and gabapentin in the treatment of painful diabetic neuropathy.
Topics: Acetaminophen; Adult; Aged; Amines; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Tramadol; Treatment Outcome | 2010 |
Can gabapentin help reduce postoperative pain in arthroscopic rotator cuff repair? A prospective, randomized, double-blind study.
Topics: Aged; Amines; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Arthroscopy; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Male; Middle Aged; Narcotics; Pain Measurement; Pain, Postoperative; Postoperative Complications; Postoperative Nausea and Vomiting; Preanesthetic Medication; Prospective Studies; Pruritus; Rotator Cuff | 2010 |
Gabapentin extended-release tablets for the treatment of patients with postherpetic neuralgia: a randomized, double-blind, placebo-controlled, multicentre study.
Topics: Administration, Oral; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain Measurement; Placebo Effect; Tablets; Time Factors; Treatment Outcome; United States | 2010 |
Pharmacokinetic profile and behavioral effects of gabapentin in the horse.
Topics: Amines; Animals; Anti-Anxiety Agents; Conscious Sedation; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Horses; Male | 2010 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intravenous; Antiemetics; Breast Neoplasms; Celecoxib; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Dexamethasone; Dextromethorphan; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Intraoperative Care; Lymph Node Excision; Mastectomy; Middle Aged; Morphine; Narcotics; Nervous System Diseases; Ondansetron; Pain, Postoperative; Pilot Projects; Postoperative Nausea and Vomiting; Preanesthetic Medication; Pyrazoles; Sentinel Lymph Node Biopsy; Sulfonamides | 2010 |
Multicenter, randomized, cross-over clinical trial of venlafaxine versus gabapentin for the management of hot flashes in breast cancer survivors.
Topics: Amines; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Breast Neoplasms; Cross-Over Studies; Cyclohexanecarboxylic Acids; Cyclohexanols; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Middle Aged; Patient Preference; Surveys and Questionnaires; Survivors; Treatment Outcome; Venlafaxine Hydrochloride | 2010 |
A comparative analysis of cetirizine, gabapentin and their combination in the relief of post-burn pruritus.
Topics: Adolescent; Adult; Aged; Amines; Analgesics; Burns; Cetirizine; Child; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Pain Measurement; Pruritus; Sex Factors; Young Adult | 2011 |
Gabapentin improves postcesarean delivery pain management: a randomized, placebo-controlled trial.
Topics: Adult; Amines; Cesarean Section; Cyclohexanecarboxylic Acids; Disease Management; Double-Blind Method; Drug Delivery Systems; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Pain, Postoperative; Postoperative Nausea and Vomiting; Pregnancy | 2011 |
Gabapentin for the treatment of carpal tunnel syndrome: a randomized controlled trial.
Topics: Adult; Amines; Analgesics; Carpal Tunnel Syndrome; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Median Nerve; Middle Aged; Placebos | 2011 |
Efficacy of gabapentin for radiculopathy caused by lumbar spinal stenosis and lumbar disk hernia.
Topics: Adult; Aged; Amines; Analgesics; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Prospective Studies; Quality of Life; Radiculopathy; Spinal Stenosis; Treatment Outcome; Young Adult | 2010 |
The effects of gabapentin on acute and chronic postoperative pain after coronary artery bypass graft surgery.
Topics: Acute Disease; Aged; Amines; Analgesics; Analgesics, Opioid; Chronic Disease; Chronic Pain; Coronary Artery Bypass; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Myocardial Revascularization; Pain Measurement; Pain, Postoperative; Prospective Studies; Sample Size; Sternotomy; Tramadol | 2011 |
Oral gabapentin for photorefractive keratectomy pain.
Topics: Acetaminophen; Administration, Oral; Adult; Amines; Analgesics; Astigmatism; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Linear Models; Male; Middle Aged; Myopia; Oxycodone; Pain Measurement; Pain, Postoperative; Photorefractive Keratectomy; Severity of Illness Index; Young Adult | 2011 |
Rapid and validated fluorometric HPLC method for determination of gabapentin in human plasma and urine for clinical application.
Topics: 4-Chloro-7-nitrobenzofurazan; Adult; Amines; Anticonvulsants; Calibration; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Fluorescent Dyes; Fluorometry; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Reproducibility of Results; Young Adult | 2012 |
Optimal dose of pre-incision/post-incision gabapentin for pain relief following lumbar laminectomy: a randomized study.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Laminectomy; Lumbar Vertebrae; Male; Middle Aged; Pain Measurement; Pain, Postoperative | 2011 |
Gabapentin for postoperative pain after photorefractive keratectomy: a prospective, randomized, double-blind, placebo-controlled trial.
Topics: Administration, Oral; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Eye Pain; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lasers, Excimer; Male; Pain, Postoperative; Photorefractive Keratectomy; Prospective Studies; Visual Acuity; Young Adult | 2011 |
Gabapentin premedication: assessment of preoperative anxiolysis and postoperative patient satisfaction.
Topics: Adult; Amines; Anti-Anxiety Agents; Anxiety; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Patient Satisfaction; Preanesthetic Medication; Prospective Studies | 2010 |
[Efficacy of gabapentin in the treatment of professional polyneuropathy].
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Electromyography; Gabapentin; gamma-Aminobutyric Acid; Hand-Arm Vibration Syndrome; Humans; Male; Middle Aged; Occupational Diseases; Polyneuropathies; Treatment Outcome | 2011 |
Gabapentin combined with naltrexone for the treatment of alcohol dependence.
Topics: Adult; Alcohol Drinking; Alcoholism; Amines; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Secondary Prevention; Substance Withdrawal Syndrome; Treatment Outcome | 2011 |
Gabapentin for the prevention of chemotherapy- induced nausea and vomiting: a pilot study.
Topics: Amines; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cyclohexanecarboxylic Acids; Dexamethasone; Double-Blind Method; Female; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Male; Middle Aged; Nausea; Ondansetron; Pilot Projects; Prospective Studies; Ranitidine; Vomiting | 2012 |
Efficacy of gabapentin on subjective idiopathic tinnitus: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Severity of Illness Index; Tinnitus; Treatment Outcome; Young Adult | 2011 |
Analgesic effect of low gynaecological surgery under general anaesthesia.
Topics: Administration, Oral; Adult; Amines; Analgesics; Analysis of Variance; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Diclofenac; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Gynecologic Surgical Procedures; Humans; Middle Aged; Pain Measurement; Pain, Postoperative; Placebos | 2010 |
The analgesic and antiemetic efficacy of gabapentin or ergotamine/caffeine for the treatment of postdural puncture headache.
Topics: Adult; Amines; Analgesics, Non-Narcotic; Antiemetics; Caffeine; Cyclohexanecarboxylic Acids; Drug Combinations; Ergotamine; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Post-Dural Puncture Headache | 2011 |
Efficacy of gabapentin enacarbil vs placebo in patients with postherpetic neuralgia and a pharmacokinetic comparison with oral gabapentin.
Topics: Adult; Aged; Amines; Analgesics; Carbamates; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Placebos; Treatment Outcome; Young Adult | 2011 |
Neurocognitive performance, alcohol withdrawal, and effects of a combination of flumazenil and gabapentin in alcohol dependence.
Topics: Adult; Alcohol Drinking; Alcoholism; Amines; Cognition; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Flumazenil; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Middle Aged; Recurrence; Substance Withdrawal Syndrome; Treatment Outcome | 2011 |
Preoperative gabapentin for acute post-thoracotomy analgesia: a randomized, double-blinded, active placebo-controlled study.
Topics: Aged; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Epidural; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Thoracotomy | 2012 |
A randomized controlled trial on medication-overuse headache: outcome after 1 and 4 years.
Topics: Adolescent; Adult; Aged; Amines; Amitriptyline; Analgesics; Angiotensin Receptor Antagonists; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders, Secondary; Humans; Male; Middle Aged; Treatment Outcome | 2011 |
Duloxetine, pregabalin, and duloxetine plus gabapentin for diabetic peripheral neuropathic pain management in patients with inadequate pain response to gabapentin: an open-label, randomized, noninferiority comparison.
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Pregabalin; Thiophenes; Treatment Outcome | 2011 |
A comparative efficacy of amitriptyline, gabapentin, and pregabalin in neuropathic cancer pain: a prospective randomized double-blind placebo-controlled study.
Topics: Adult; Amines; Amitriptyline; Analgesics; Analysis of Variance; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Morphine; Neoplasms; Neuralgia; Pain Measurement; Pregabalin; Prospective Studies | 2012 |
High-volume infiltration analgesia in bilateral hip arthroplasty. A randomized, double-blind placebo-controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Amides; Amines; Analgesics; Anesthesia, Local; Anesthetics, Local; Arthroplasty, Replacement, Hip; Celecoxib; Cyclohexanecarboxylic Acids; Double-Blind Method; Epinephrine; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intraoperative Care; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Pyrazoles; Ropivacaine; Sulfonamides | 2011 |
Effects of gabapentin on postoperative pain, nausea and vomiting after abdominal hysterectomy: a double blind randomized clinical trial.
Topics: Adult; Amines; Analgesics; Antiemetics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Meperidine; Middle Aged; Pain, Postoperative; Postoperative Nausea and Vomiting | 2012 |
Importance of gabapentin dose in treatment of opioid withdrawal.
Topics: Adult; Amines; Analgesics, Opioid; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Methadone; Middle Aged; Opiate Substitution Treatment; Opioid-Related Disorders; Severity of Illness Index; Substance Withdrawal Syndrome; Treatment Outcome; Young Adult | 2011 |
[Biological age and the pain syndrome at diabetic polyneuropathy].
Topics: Adult; Aging; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Selective Serotonin Reuptake Inhibitors; Syndrome; Thiophenes; Treatment Outcome | 2011 |
Costs and health resources utilization following switching to pregabalin in individuals with gabapentin-refractory neuropathic pain: a post hoc analysis.
Topics: Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Health Care Costs; Health Resources; Humans; Male; Middle Aged; Neuralgia; Pregabalin; Spain | 2012 |
Double-blind placebo-controlled evaluation of the PROMETA™ protocol for methamphetamine dependence.
Topics: Adult; Amines; Amphetamine-Related Disorders; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Combinations; Female; Flumazenil; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Histamine Agonists; Humans; Hydroxyzine; Infusions, Intravenous; Male; Medication Adherence; Methamphetamine; Self Report | 2012 |
Gabapentin: a novel drug as add-on therapy in cases of refractory overactive bladder in children.
Topics: Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cholinergic Antagonists; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Prospective Studies; Treatment Outcome; Urinary Bladder; Urinary Bladder, Overactive; Urodynamics | 2013 |
Effect of pre-emptive gabapentin on postoperative pain following lower extremity orthopaedic surgery under spinal anaesthesia.
Topics: Adult; Amines; Anesthesia, Spinal; Anesthesiology; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fracture Fixation, Internal; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Morphine; Orthopedics; Pain; Pain, Postoperative; Placebos; Tibia; Time Factors; Treatment Outcome | 2011 |
Perioperative administration of gabapentin 1,200 mg day-1 and pregabalin 300 mg day-1 for pain following lumbar laminectomy and discectomy: a randomised, double-blinded, placebo-controlled study.
Topics: Adult; Aged; Amines; Analgesics; Anesthesiology; Cyclohexanecarboxylic Acids; Diskectomy; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Laminectomy; Lumbar Vertebrae; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Placebos; Pregabalin | 2011 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Catheterization, Peripheral; Cyclohexanecarboxylic Acids; Drug Combinations; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intraoperative Care; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Nerve Block; Pain Measurement; Pain, Postoperative; Pilot Projects; Pneumonectomy; Prospective Studies; Thoracic Surgery, Video-Assisted; Treatment Outcome | 2012 |
Impact of concomitant antacid administration on gabapentin plasma exposure and oral bioavailability in healthy adult subjects.
Topics: Administration, Oral; Adult; Amines; Antacids; Biological Availability; Cross-Over Studies; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Intestinal Absorption; Magnesium Oxide; Male; Young Adult | 2012 |
Analgesic effects of preoperative gabapentin after tongue reconstruction with the anterolateral thigh flap.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Amines; Analgesia, Patient-Controlled; Analgesics; Antiemetics; Cohort Studies; Cyclohexanecarboxylic Acids; Female; Free Tissue Flaps; Gabapentin; gamma-Aminobutyric Acid; Hong Kong; Humans; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Plastic Surgery Procedures; Postoperative Nausea and Vomiting; Preoperative Care; Retrospective Studies; Thigh; Tongue Neoplasms | 2012 |
Efficacy of gabapentin for prevention of postoperative catheter-related bladder discomfort in patients undergoing transurethral resection of bladder tumor.
Topics: Adult; Amines; Anticonvulsants; Catheters, Indwelling; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain, Postoperative; Preoperative Period; Urinary Bladder; Urinary Bladder Neoplasms; Urinary Catheterization; Young Adult | 2012 |
Comparison of substance use milestones in cannabis- and cocaine-dependent patients.
Topics: Adult; Age of Onset; Amines; Antidepressive Agents, Second-Generation; Bupropion; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Combinations; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Marijuana Abuse; Piperazines; Triazoles; Young Adult | 2012 |
A proof-of-concept randomized controlled study of gabapentin: effects on cannabis use, withdrawal and executive function deficits in cannabis-dependent adults.
Topics: Adolescent; Adult; Amines; Calcium Channel Blockers; Cannabis; Counseling; Cyclohexanecarboxylic Acids; Double-Blind Method; Executive Function; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Marijuana Abuse; Middle Aged; Substance Withdrawal Syndrome; Treatment Outcome | 2012 |
Prognostic factors for time to treatment failure and time to 12 months of remission for patients with focal epilepsy: post-hoc, subgroup analyses of data from the SANAD trial.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Disease-Free Survival; Epilepsies, Partial; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Oxcarbazepine; Prognosis; Time Factors; Topiramate; Treatment Failure; Triazines; Young Adult | 2012 |
Chronic postthoracotomy pain and health-related quality of life.
Topics: Aged; Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Humans; Male; Middle Aged; Pain, Postoperative; Prospective Studies; Quality of Life; Surveys and Questionnaires; Thoracotomy | 2012 |
Perioperative administration of gabapentin for shoulder arthroscopy: a prospective, randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesics; Arthroscopy; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Morphine; Nerve Block; Pain, Postoperative; Prospective Studies; Shoulder Joint | 2011 |
A gastroretentive gabapentin formulation for the treatment of painful diabetic peripheral neuropathy: efficacy and tolerability in a double-blind, randomized, controlled clinical trial.
Topics: Aged; Algorithms; Amines; Analgesics; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; Gabapentin; gamma-Aminobutyric Acid; Gastric Emptying; Humans; Male; Middle Aged; Placebos; Treatment Outcome | 2012 |
Analysis of exposure-response of CI-945 in patients with epilepsy: application of novel mixed hidden Markov modeling methodology.
Topics: Adolescent; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Markov Chains; Middle Aged; Young Adult | 2012 |
Pregabalin and gabapentin for post-photorefractive keratectomy pain: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Adult; Amines; Analgesics; Codeine; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Eye Pain; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain Measurement; Pain, Postoperative; Photorefractive Keratectomy; Pregabalin; Prospective Studies; Treatment Outcome; Young Adult | 2012 |
Pharmacokinetic of gabapentin 600 mg tablet in Thai healthy subjects.
Topics: Administration, Oral; Adult; Amines; Anticonvulsants; Area Under Curve; Biological Availability; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Reference Values; Tablets; Young Adult | 2012 |
Gabapentin versus pregabalin in improving sleep quality and depression in hemodialysis patients with peripheral neuropathy: a randomized prospective crossover trial.
Topics: Amines; Anti-Anxiety Agents; Calcium Channel Blockers; Cross-Over Studies; Cyclohexanecarboxylic Acids; Depression; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Male; Middle Aged; Peripheral Nervous System Diseases; Pregabalin; Prospective Studies; Quality of Life; Renal Dialysis; Sleep; Sleep Wake Disorders; Surveys and Questionnaires; Treatment Outcome | 2013 |
Four treatment strategies for complex regional pain syndrome type 1.
Topics: Administration, Oral; Adult; Aged; Amines; Analgesics; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Dexamethasone; Diclofenac; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mannitol; Middle Aged; Pain Measurement; Reflex Sympathetic Dystrophy; Treatment Outcome | 2012 |
Sensory and affective pain descriptors respond differentially to pharmacological interventions in neuropathic conditions.
Topics: Amines; Analgesics; Case-Control Studies; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Linear Models; Male; Morphine; Neuralgia; Pain Measurement; Pain Perception; Predictive Value of Tests; Treatment Outcome | 2013 |
Early pain reduction can predict treatment response: results of integrated efficacy analyses of a once-daily gastroretentive formulation of gabapentin in patients with postherpetic neuralgia.
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain Measurement; Predictive Value of Tests; Time Factors; Treatment Outcome | 2012 |
Effects of a single 1200-mg preoperative dose of gabapentin on anxiety and memory.
Topics: Adult; Aged; Amines; Analgesics; Anesthesia, General; Anti-Anxiety Agents; Anxiety; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Male; Memory; Middle Aged; Neuropsychological Tests; Postoperative Complications; Preoperative Care; Prospective Studies; Psychiatric Status Rating Scales; Surgical Procedures, Operative; Treatment Outcome | 2012 |
Steady-state pharmacokinetics of gabapentin after administration of a novel gastroretentive extended-release formulation in postmenopausal women with vasomotor symptoms.
Topics: Amines; Area Under Curve; Biological Availability; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Middle Aged; Placebos; Postmenopause | 2012 |
Gastroretentive gabapentin (G-GR) formulation reduces intensity of pain associated with postherpetic neuralgia (PHN).
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain Measurement; Severity of Illness Index; Treatment Outcome | 2013 |
Uremic pruritus in hemodialysis patients: treatment with desloratidine versus gabapentin.
Topics: Amines; Cross-Over Studies; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Middle Aged; Prospective Studies; Pruritus; Renal Dialysis; Uremia | 2012 |
Assessment of the effects of adjunctive gabapentin on postoperative pain after intervertebral disc surgery in dogs.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dog Diseases; Dogs; Female; Gabapentin; gamma-Aminobutyric Acid; Intervertebral Disc Degeneration; Male; Pain, Postoperative | 2012 |
Pregabalin versus gabapentin in the treatment of neuropathic pruritus in maintenance haemodialysis patients: a prospective, crossover study.
Topics: Adult; Aged; Amines; Analgesics; Antipruritics; Chi-Square Distribution; Cross-Over Studies; Cyclohexanecarboxylic Acids; Electromyography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Pregabalin; Prospective Studies; Pruritus; Renal Dialysis; Surveys and Questionnaires; Time Factors; Treatment Outcome; Turkey | 2012 |
Study of haemodynamic and endocrine stress responses following carbon dioxide pneumoperitonium.
Topics: Adult; Amines; Anti-Anxiety Agents; Blood Glucose; Carbon Dioxide; Cholecystectomy, Laparoscopic; Clonidine; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Hemodynamics; Humans; Hydrocortisone; Male; Middle Aged; Nepal; Pneumoperitoneum, Artificial; Premedication; Prospective Studies; Sympatholytics; Treatment Outcome | 2012 |
The efficacy of gabapentin versus stabilization splint in management of sleep bruxism.
Topics: Adolescent; Adult; Amines; Centric Relation; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Masseter Muscle; Middle Aged; Muscle Contraction; Occlusal Splints; Orthodontic Appliance Design; Polysomnography; Single-Blind Method; Sleep; Sleep Bruxism; Sleep Stages; Treatment Outcome; Young Adult | 2013 |
Gabapentin for refractory chronic cough: a randomised, double-blind, placebo-controlled trial.
Topics: Adolescent; Adult; Amines; Anticonvulsants; Central Nervous System; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurotransmitter Agents; Quality of Life; Reflex; Young Adult | 2012 |
Adjunctive treatment with gabapentin in bipolar patients during acute mania.
Topics: Acute Disease; Age Distribution; Amines; Analysis of Variance; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Iran; Lithium Compounds; Male; Psychiatric Status Rating Scales; Sex Distribution; Treatment Outcome | 2012 |
A single preoperative dose of gabapentin does not improve postcesarean delivery pain management: a randomized, double-blind, placebo-controlled dose-finding trial.
Topics: Adult; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesia, Spinal; Apgar Score; Cesarean Section; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Endpoint Determination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Pregnancy; Pregnancy Outcome; Sample Size | 2012 |
A randomized, controlled, double-blinded clinical trial of gabapentin 300 versus 900 mg versus placebo for anxiety symptoms in breast cancer survivors.
Topics: Amines; Anti-Anxiety Agents; Anxiety; Breast Neoplasms; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Survivors; Treatment Outcome | 2012 |
Once-daily gastroretentive gabapentin for postherpetic neuralgia: integrated efficacy, time to onset of pain relief and safety analyses of data from two phase 3, multicenter, randomized, double-blind, placebo-controlled studies.
Topics: Amines; Analgesics; Causality; Comorbidity; Cyclohexanecarboxylic Acids; Disorders of Excessive Somnolence; Dizziness; Dosage Forms; Dose-Response Relationship, Drug; Double-Blind Method; Drug Compounding; Drug-Related Side Effects and Adverse Reactions; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia, Postherpetic; Pain Measurement; Placebo Effect; Prevalence; Risk Factors; Treatment Outcome; United States | 2013 |
Effect of gabapentin on postoperative pain and operation complications: a randomized placebo controlled trial.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Middle Aged; Pain, Postoperative; Postoperative Complications; Postoperative Nausea and Vomiting | 2012 |
Effects of preoperative gabapentin on postoperative pain after radical retropubic prostatectomy.
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesia, Patient-Controlled; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Narcotics; Pain Measurement; Pain, Postoperative; Prospective Studies; Prostatectomy; Tramadol | 2012 |
Long-term safety of gastroretentive gabapentin in postherpetic neuralgia patients.
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Longitudinal Studies; Male; Middle Aged; Neuralgia, Postherpetic; Pain Measurement; Treatment Outcome | 2013 |
[Neuropathy pain: tactic of treatment].
Topics: Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Thiamine; Treatment Outcome; Ukraine | 2012 |
Gabapentin reduces preoperative anxiety and pain catastrophizing in highly anxious patients prior to major surgery: a blinded randomized placebo-controlled trial.
Topics: Adult; Amines; Analysis of Variance; Anti-Anxiety Agents; Anxiety; Catastrophization; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Hospitals, General; Humans; Middle Aged; Pain; Preoperative Care; Treatment Outcome | 2013 |
Effects of a GABA-ergic medication combination and initial alcohol withdrawal severity on cue-elicited brain activation among treatment-seeking alcoholics.
Topics: Adult; Alcohol Drinking; Alcoholism; Amines; Brain; Cues; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Flumazenil; Follow-Up Studies; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Secondary Prevention; Severity of Illness Index; Substance Withdrawal Syndrome; Treatment Outcome | 2013 |
Population pharmacokinetics and pharmacodynamics of gabapentin after administration of gabapentin enacarbil.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Carbamates; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Models, Biological; Prodrugs; Restless Legs Syndrome; Sleep Initiation and Maintenance Disorders; Young Adult | 2013 |
The pharmacokinetics and effects of meloxicam, gabapentin, and flunixin in postweaning dairy calves following dehorning with local anesthesia.
Topics: Amines; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Clonixin; Cyclohexanecarboxylic Acids; Dairying; Gabapentin; gamma-Aminobutyric Acid; Horns; Male; Meloxicam; Pain Measurement; Pain, Postoperative; Thiazines; Thiazoles | 2013 |
Gabapentin does not improve multimodal analgesia outcomes for total knee arthroplasty: a randomized controlled trial.
Topics: Acetaminophen; Aged; Amines; Analgesia, Patient-Controlled; Analgesics; Arthroplasty, Replacement, Knee; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketorolac; Length of Stay; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Time Factors; Treatment Outcome | 2013 |
Uraemic pruritus: relief of itching by gabapentin and pregabalin.
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Comorbidity; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pregabalin; Prevalence; Pruritus; Renal Insufficiency, Chronic; Risk Factors; Treatment Outcome; United Kingdom; Uremia | 2012 |
Pregnancy outcomes following gabapentin use: results of a prospective comparative cohort study.
Topics: Abnormalities, Drug-Induced; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregnancy; Pregnancy Outcome; Prospective Studies | 2013 |
Effect of a preoperative gabapentin on postoperative analgesia in patients with inflammatory bowel disease following major bowel surgery: a randomized, placebo-controlled trial.
Topics: Abdomen; Adult; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Inflammatory Bowel Diseases; Length of Stay; Lower Gastrointestinal Tract; Male; Movement; Pain Measurement; Pain, Postoperative; Recovery of Function; Rest; Treatment Outcome | 2014 |
Cross-over, open-label trial of the effects of gabapentin versus pregabalin on painful peripheral neuropathy and health-related quality of life in haemodialysis patients.
Topics: Adult; Aged; Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Peripheral Nervous System Diseases; Pregabalin; Prospective Studies; Quality of Life; Renal Dialysis; Surveys and Questionnaires; Treatment Outcome | 2013 |
The effect of gabapentin premedication on postoperative nausea, vomiting, and pain in patients on preoperative dexamethasone undergoing craniotomy for intracranial tumors.
Topics: Adult; Amines; Anesthesia; Anti-Inflammatory Agents; Brain Neoplasms; Craniotomy; Cyclohexanecarboxylic Acids; Dexamethasone; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Odds Ratio; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Preanesthetic Medication | 2013 |
Oral gabapentin premedication for elderly patients undergoing intraocular surgery.
Topics: Administration, Oral; Amines; Analgesics; Anesthesia, Conduction; Anti-Anxiety Agents; Blood Pressure; Cyclohexanecarboxylic Acids; Diazepam; Double-Blind Method; Eye Pain; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Humans; Intraocular Pressure; Male; Midazolam; Middle Aged; Pain, Postoperative; Phacoemulsification; Premedication | 2013 |
The efficacy of gabapentin in children of partial seizures and the blood levels.
Topics: Adolescent; Age Factors; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Prospective Studies; Seizures; Sex Factors; Time Factors; Treatment Outcome | 2014 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Case-Control Studies; Cyclohexanecarboxylic Acids; Dexamethasone; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain, Postoperative; Postoperative Nausea and Vomiting; Spinal Diseases; Spinal Fusion; Young Adult | 2013 |
Interchangeability of gabapentin generic formulations in the Netherlands: a comparative bioavailability study.
Topics: Adult; Amines; Anticonvulsants; Biological Availability; Chemistry, Pharmaceutical; Cross-Over Studies; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Tablets; Therapeutic Equivalency | 2013 |
Effect of gabapentin pretreatment on propofol consumption, hemodynamic variables, and postoperative pain relief in breast cancer surgery.
Topics: Adult; Amines; Analgesics; Anesthetics, Intravenous; Breast Neoplasms; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Hemodynamics; Humans; Middle Aged; Morphine; Pain, Postoperative; Propofol; Prospective Studies | 2013 |
The importance of communication in the management of postoperative pain.
Topics: Acetaminophen; Adult; Amines; Analgesics; Analgesics, Opioid; Celecoxib; Communication; Cyclohexanecarboxylic Acids; Drug Prescriptions; Endorphins; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocodone; Middle Aged; Pain Management; Pain Measurement; Pain, Postoperative; Patient Education as Topic; Patient Preference; Preoperative Care; Pyrazoles; Sulfonamides; Young Adult | 2013 |
Rationale and design of a multicenter randomized clinical trial of extended release gabapentin in provoked vestibulodynia and biological correlates of response.
Topics: Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Dyspareunia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Research Design; Vulvodynia | 2013 |
Intrathecal gabapentin to treat chronic intractable noncancer pain.
Topics: Adult; Aged; Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Male; Middle Aged; Pain, Intractable | 2013 |
Randomized, placebo-controlled pilot trial of gabapentin during an outpatient, buprenorphine-assisted detoxification procedure.
Topics: Adult; Amines; Buprenorphine; Cyclohexanecarboxylic Acids; Diagnostic and Statistical Manual of Mental Disorders; Directly Observed Therapy; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Induction Chemotherapy; Maintenance Chemotherapy; Male; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Patient Dropouts; Pilot Projects; Secondary Prevention; Severity of Illness Index; Substance Withdrawal Syndrome | 2013 |
Comparison of efficacy and safety of topiramate with gabapentin in migraine prophylaxis: randomized open label control trial.
Topics: Adult; Amines; Analgesics; Cohort Studies; Cyclohexanecarboxylic Acids; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Migraine Disorders; Neuroprotective Agents; Topiramate; Treatment Outcome; Young Adult | 2013 |
The effects of gabapentin on methadone based addiction treatment: a randomized controlled trial.
Topics: Adult; Amines; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Iran; Male; Methadone; Middle Aged; Opiate Substitution Treatment; Opioid-Related Disorders; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome; Young Adult | 2013 |
Low single dose gabapentin does not affect prefrontal and occipital gamma-aminobutyric acid concentrations.
Topics: Adult; Amines; Analysis of Variance; Anticonvulsants; Aspartic Acid; Choline; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Occipital Lobe; Prefrontal Cortex; Young Adult | 2013 |
Phase 3 randomized controlled study of gastroretentive gabapentin for the treatment of moderate-to-severe hot flashes in menopause.
Topics: Adult; Aged; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Disorders of Excessive Somnolence; Dizziness; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Middle Aged; Prospective Studies; Severity of Illness Index | 2014 |
Duloxetine Compared with Pregabalin for Diabetic Peripheral Neuropathic Pain Management in Patients with Suboptimal Pain Response to Gabapentin and Treated with or without Antidepressants: A Post Hoc Analysis.
Topics: Adult; Aged; Amines; Analgesics; Antidepressive Agents; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Management; Pain Measurement; Pregabalin; Treatment Outcome | 2014 |
Safety and efficacy of once-daily gastroretentive gabapentin in patients with postherpetic neuralgia aged 75 years and over.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Gastric Mucosa; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Tissue Distribution; Treatment Outcome; Young Adult | 2013 |
Effect of mushroom diet on pharmacokinetics of gabapentin in healthy Chinese subjects.
Topics: Administration, Oral; Adult; Agaricales; Amines; Anticonvulsants; Asian People; China; Cyclohexanecarboxylic Acids; Diet; Ergothioneine; Gabapentin; gamma-Aminobutyric Acid; Genotype; Healthy Volunteers; Herb-Drug Interactions; Humans; Male; Middle Aged; Organic Cation Transport Proteins; Symporters | 2014 |
The effect of gabapentin on intensity and duration of hot flashes in postmenopausal women: a randomized controlled trial.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Middle Aged; Postmenopause | 2013 |
Gabapentin treatment for alcohol dependence: a randomized clinical trial.
Topics: Adult; Alcohol Abstinence; Alcoholism; Amines; Central Nervous System Depressants; Cyclohexanecarboxylic Acids; Double-Blind Method; Ethanol; Female; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Substance Withdrawal Syndrome; Treatment Outcome | 2014 |
A randomized double-blinded placebo controlled study of four interventions for the prevention of postoperative nausea and vomiting in maxillofacial trauma surgery.
Topics: Adolescent; Adult; Aged, 80 and over; Amines; Antiemetics; Child; Chlorpromazine; Cyclohexanecarboxylic Acids; Dexamethasone; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Follow-Up Studies; Fracture Fixation, Internal; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Humans; Male; Maxillofacial Injuries; Metoclopramide; Middle Aged; Placebos; Postoperative Nausea and Vomiting; Premedication; Prospective Studies; Treatment Outcome; Young Adult | 2013 |
Donepezil provides positive effects to patients treated with gabapentin for neuropathic pain: an exploratory study.
Topics: Adult; Aged; Algorithms; Amines; Analgesics; Cyclohexanecarboxylic Acids; Cyclohexanols; Donepezil; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Male; Middle Aged; Neuralgia; Neuroprotective Agents; Pain Measurement; Piperidines; Quality of Life; Sample Size; Venlafaxine Hydrochloride | 2014 |
Gabapentin premedication for postoperative analgesia and emergence agitation after sevoflurane anesthesia in pediatric patients.
Topics: Amines; Anesthesia, General; Anesthetics, Inhalation; Anti-Anxiety Agents; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Delirium; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Methyl Ethers; Postoperative Complications; Premedication; Sevoflurane; Treatment Outcome | 2013 |
Postoperative pain and long-term functional outcome after administration of gabapentin and pregabalin in patients undergoing spinal surgery.
Topics: Adolescent; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Disability Evaluation; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; India; Male; Middle Aged; Orthopedic Procedures; Pain Measurement; Pain, Postoperative; Pregabalin; Prospective Studies; Quality of Life; Recovery of Function; Spine; Surveys and Questionnaires; Time Factors; Young Adult | 2014 |
The effect of gabapentin versus intrathecal fentanyl on postoperative pain and morphine consumption in cesarean delivery: a prospective, randomized, double-blind study.
Topics: Adult; Amines; Analgesics; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Cesarean Section; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Morphine; Outcome Assessment, Health Care; Pain, Postoperative; Pregnancy; Prospective Studies | 2014 |
Clinical efficacy of sertraline alone and augmented with gabapentin in recently abstinent cocaine-dependent patients with depressive symptoms.
Topics: Adult; Amines; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Depression; Diagnosis, Dual (Psychiatry); Double-Blind Method; Drug Therapy, Combination; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medication Adherence; Patient Compliance; Recurrence; Selective Serotonin Reuptake Inhibitors; Sertraline; Young Adult | 2014 |
Comparison between the combination of gabapentin, ketamine, lornoxicam, and local ropivacaine and each of these drugs alone for pain after laparoscopic cholecystectomy: a randomized trial.
Topics: Adult; Amides; Amines; Cholecystectomy, Laparoscopic; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Middle Aged; Pain Management; Pain Measurement; Pain, Postoperative; Piroxicam; Ropivacaine | 2015 |
Perioperative gabapentin for the prevention of persistent pain after thoracotomy: a randomized controlled trial.
Topics: Adult; Aged; Amines; Analgesics; Analgesics, Opioid; Anesthetics, Local; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lung Neoplasms; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Perioperative Care; Thoracotomy; Young Adult | 2014 |
[Diagnosis and treatment of polyneuropathy].
Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Extremities; Gabapentin; gamma-Aminobutyric Acid; Hand-Arm Vibration Syndrome; Humans; Male; Middle Aged; Polyneuropathies; Vibration | 2014 |
Multimodal analgesia versus traditional opiate based analgesia after cardiac surgery, a randomized controlled trial.
Topics: Acetaminophen; Aged; Amines; Analgesia; Analgesics; Analgesics, Opioid; Cardiac Surgical Procedures; Cyclohexanecarboxylic Acids; Dexamethasone; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ibuprofen; Male; Middle Aged; Pain Management; Pain, Postoperative; Prospective Studies | 2014 |
Clinical study evaluating pregabalin efficacy and tolerability for pain management in patients undergoing laparoscopic cholecystectomy.
Topics: Adult; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, Laparoscopic; Cyclohexanecarboxylic Acids; Diclofenac; Dizziness; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Meperidine; Middle Aged; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Postoperative Nausea and Vomiting; Pregabalin; Prospective Studies; Young Adult | 2014 |
Comparative safety and tolerability of duloxetine vs. pregabalin vs. duloxetine plus gabapentin in patients with diabetic peripheral neuropathic pain.
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Peripheral Nervous System Diseases; Pregabalin; Treatment Outcome | 2014 |
Gabapentin versus pregabalin in relieving early post-surgical neuropathic pain in patients after lumbar disc herniation surgery: a prospective clinical trial.
Topics: Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diskectomy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Neuralgia; Pain Measurement; Pregabalin; Prospective Studies; Treatment Outcome | 2014 |
[Preemptive analgesic efficacy of gabapentin and nimesulide in the functional endoscopic sinus surgery].
Topics: Adolescent; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Endoscopy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Paranasal Sinus Diseases; Sulfonamides; Treatment Outcome; Young Adult | 2014 |
Perioperative gabapentin reduces 24 h opioid consumption and improves in-hospital rehabilitation but not post-discharge outcomes after total knee arthroplasty with peripheral nerve block.
Topics: Adolescent; Adult; Aged; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nerve Block; Pain Measurement; Pain, Postoperative; Perioperative Care; Postoperative Care; Range of Motion, Articular; Treatment Outcome; Young Adult | 2014 |
Gabapentin versus naproxen in the management of failed back surgery syndrome; a randomized controlled trial.
Topics: Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Failed Back Surgery Syndrome; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Iran; Male; Middle Aged; Naproxen; Pain Measurement; Treatment Outcome | 2014 |
Phase III double-blind, placebo-controlled study of gabapentin for the prevention of delayed chemotherapy-induced nausea and vomiting in patients receiving highly emetogenic chemotherapy, NCCTG N08C3 (Alliance).
Topics: Adult; Aged; Amines; Antineoplastic Agents; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nausea; Neoplasms; Patient Satisfaction; Time Factors; Vomiting | 2014 |
Analgesic efficacy of prophylactic gabapentin and lornoxicam in preventing postendodontic pain.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain; Pain Management; Pain Measurement; Piroxicam; Prospective Studies; Root Canal Therapy | 2014 |
The effects of gabapentin on severity of post spinal anesthesia headache.
Topics: Adult; Amines; Analgesics; Anesthesia, Spinal; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Morphine; Pain, Postoperative; Post-Dural Puncture Headache | 2014 |
Single dose pharmacokinetic equivalence study of two gabapentin preparations in healthy subjects.
Topics: Adult; Amines; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Healthy Volunteers; Humans; Male; Middle Aged; Single-Blind Method; Therapeutic Equivalency; Young Adult | 2014 |
Perioperative gabapentin and delirium following total knee arthroplasty: a post-hoc analysis of a double-blind randomized placebo-controlled trial.
Topics: Aged; Amines; Analgesics; Arthroplasty, Replacement, Knee; Cyclohexanecarboxylic Acids; Delirium; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain, Postoperative; Postoperative Complications | 2014 |
The effect of a combination of gabapentin and donepezil in an experimental pain model in healthy volunteers: Results of a randomized controlled trial.
Topics: Adolescent; Adult; Amines; Analgesics, Non-Narcotic; Cross-Over Studies; Cyclohexanecarboxylic Acids; Donepezil; Double-Blind Method; Drug Therapy, Combination; Electric Stimulation; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Healthy Volunteers; Humans; Indans; Male; Middle Aged; Nootropic Agents; Pain; Pain Measurement; Piperidines; Skin; Sural Nerve; Young Adult | 2014 |
Analgesic effects of gabapentin after scoliosis surgery in children: a randomized controlled trial.
Topics: Adolescent; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Morphine; Orthopedic Procedures; Pain Measurement; Pain, Postoperative; Postoperative Complications; Postoperative Nausea and Vomiting; Scoliosis; Treatment Outcome | 2014 |
Oral gabapentin and intradermal injection of lidocaine: is there any role in the treatment of moderate/severe tinnitus?
Topics: Administration, Oral; Adult; Amines; Anesthetics, Local; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intradermal; Lidocaine; Male; Middle Aged; Prospective Studies; Severity of Illness Index; Tinnitus; Treatment Outcome; Young Adult | 2015 |
Comparison of the effectiveness between generic and original form of gabapentin for pain relief in suspected neuropathic component of low back pain.
Topics: Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drugs, Generic; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Lumbar Vertebrae; Male; Middle Aged; Pain Measurement; Single-Blind Method | 2014 |
Gabapentin significantly decreases posthemorrhoidectomy pain: a prospective study.
Topics: Adult; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hemorrhoidectomy; Humans; Male; Middle Aged; Pain, Postoperative; Prospective Studies | 2014 |
Nabilone as an adjunctive to gabapentin for multiple sclerosis-induced neuropathic pain: a randomized controlled trial.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Dronabinol; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Neuralgia; Pain Measurement | 2015 |
A randomized, double-blind, single-dose, placebo-controlled, multicenter, polysomnographic study of gabapentin in transient insomnia induced by sleep phase advance.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Polysomnography; Sleep Initiation and Maintenance Disorders; Sleep Stages; Treatment Outcome; Young Adult | 2014 |
A randomized, double-blind, placebo-controlled, multicenter, 28-day, polysomnographic study of gabapentin in transient insomnia induced by sleep phase advance.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Polysomnography; Sleep Initiation and Maintenance Disorders; Sleep Stages; Treatment Outcome; Young Adult | 2014 |
Epidural steroid injections, conservative treatment, or combination treatment for cervical radicular pain: a multicenter, randomized, comparative-effectiveness study.
Topics: Adult; Amines; Analgesics; Antidepressive Agents, Tricyclic; Cervical Vertebrae; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Epidural; Male; Middle Aged; Neck Pain; Nortriptyline; Pain Measurement; Physical Therapy Modalities; Prospective Studies; Steroids; Treatment Outcome | 2014 |
Gabapentin-induced changes of plasma cortisol level and immune status in hysterectomized women.
Topics: Amines; Antigens, CD; B-Lymphocytes; Catecholamines; Cyclohexanecarboxylic Acids; Female; Flow Cytometry; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocortisone; Hysterectomy; Immunomodulation; Killer Cells, Natural; Lymphocyte Count; Pain Measurement; Pain, Postoperative; Predictive Value of Tests; Regression Analysis; Stress, Psychological | 2014 |
Gabapentin enacarbil and morphine administered in combination versus alone: a double-blind, randomized, pharmacokinetic, and tolerability comparison.
Topics: Adult; Amines; Analgesics, Opioid; Carbamates; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dizziness; Double-Blind Method; Dyssomnias; Electrocardiography; Gabapentin; gamma-Aminobutyric Acid; Healthy Volunteers; Humans; Male; Middle Aged; Morphine; Nausea; Prodrugs; Young Adult | 2015 |
The effect of triple vs. double nonopioid therapy on postoperative pain and functional outcome after abdominal hysterectomy: a randomised double-blind control trial.
Topics: Acetaminophen; Adult; Amines; Analgesia, Patient-Controlled; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Early Termination of Clinical Trials; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Meloxicam; Middle Aged; Morphine; Ontario; Pain Measurement; Pain, Postoperative; Recovery of Function; Thiazines; Thiazoles; Time Factors; Treatment Outcome | 2015 |
Acceptable effect of multimodal analgesic treatment after a Bascom cleft lift operation.
Topics: Acetaminophen; Adolescent; Adult; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Cyclohexanecarboxylic Acids; Dexamethasone; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Pilonidal Sinus; Postoperative Nausea and Vomiting; Prospective Studies; Young Adult | 2015 |
Pharmacokinetic effects of simultaneous administration of single-dose gabapentin 500 mg and zolpidem tartrate 10 mg in healthy volunteers: a randomized, open-label, crossover trial.
Topics: Adolescent; Adult; Amines; Area Under Curve; Cross-Over Studies; Cyclohexanecarboxylic Acids; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pyridines; Therapeutic Equivalency; Young Adult; Zolpidem | 2015 |
Gabapentin versus levodopa-c for the treatment of restless legs syndrome in hemodialysis patients: a randomized clinical trial.
Topics: Adult; Aged; Amines; Carbidopa; Cyclohexanecarboxylic Acids; Drug Combinations; Gabapentin; gamma-Aminobutyric Acid; Humans; Iran; Levodopa; Male; Middle Aged; Motor Activity; Renal Dialysis; Restless Legs Syndrome; Sleep; Surveys and Questionnaires; Time Factors; Treatment Outcome | 2015 |
Randomized controlled trial of gabapentin as an adjunct to perioperative analgesia in total hip arthroplasty patients.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketorolac; Length of Stay; Male; Middle Aged; Morphine; Pain, Postoperative; Young Adult | 2015 |
Relationships Among Adverse Events, Disease Characteristics, and Demographics in Treatment of Postherpetic Neuralgia With Gastroretentive Gabapentin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neuralgia, Postherpetic; Pain Measurement; Risk Factors; Severity of Illness Index; Sex Factors; Treatment Outcome; Young Adult | 2015 |
Epidural steroid injections compared with gabapentin for lumbosacral radicular pain: multicenter randomized double blind comparative efficacy study.
Topics: Adult; Amines; Analgesics; Analysis of Variance; Anti-Inflammatory Agents; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Epidural; Low Back Pain; Male; Methylprednisolone; Middle Aged; Pain Measurement; Radiculopathy | 2015 |
Myofascial pain: an open study on the pharmacotherapeutic response to stepped treatment with tricyclic antidepressants and gabapentin.
Topics: Adult; Age Factors; Amines; Amitriptyline; Antidepressive Agents, Tricyclic; Comorbidity; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Masticatory Muscles; Medical Records; Middle Aged; Myalgia; Neck Muscles; Nortriptyline; Pain Measurement; Palpation; Prospective Studies; Temporomandibular Joint Dysfunction Syndrome; Treatment Outcome; Young Adult | 2015 |
Relationships Among Pain Quality, Pain Impact, and Overall Improvement in Patients with Postherpetic Neuralgia Treated with Gastroretentive Gabapentin.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain Measurement; Quality of Life; Treatment Outcome | 2015 |
Comparing Gabapentin with Clonazepam for Residual Sleeping Problems following Antidepressant Therapy in Patients with Major Depressive Disorder: A Randomized Clinical Trial.
Topics: Adult; Amines; Antidepressive Agents; Clonazepam; Cyclohexanecarboxylic Acids; Depressive Disorder, Major; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Sleep Wake Disorders | 2015 |
Can pregabalin prevent paclitaxel-associated neuropathy?--An ACCRU pilot trial.
Topics: Acute Pain; Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypesthesia; Male; Middle Aged; Neoplasms; Paclitaxel; Paresthesia; Peripheral Nervous System Diseases; Pilot Projects; Placebos; Pregabalin; Quality of Life; Surveys and Questionnaires | 2016 |
A crossover study comparing gabapentin and fluoxetine for the treatment of vasomotor symptoms among postmenopausal women.
Topics: Amines; Cross-Over Studies; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Iran; Middle Aged; Postmenopause; Selective Serotonin Reuptake Inhibitors; Surveys and Questionnaires; Sweating; Treatment Outcome | 2015 |
A Perioperative Course of Gabapentin Does Not Produce a Clinically Meaningful Improvement in Analgesia after Cesarean Delivery: A Randomized Controlled Trial.
Topics: Adult; Amines; Analgesics; Cesarean Section; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Pain, Postoperative; Perioperative Care; Pregnancy; Treatment Outcome | 2015 |
Analgesic and sedative effects of perioperative gabapentin in total knee arthroplasty: a randomized, double-blind, placebo-controlled dose-finding study.
Topics: Aged; Aged, 80 and over; Amines; Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Cyclohexanecarboxylic Acids; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Male; Middle Aged; Morphine; Nausea; Pain Measurement; Pain, Postoperative; Sleep; Treatment Outcome; Vomiting | 2015 |
Comparison of gabapentin versus topiramate on clinically affected dogs with Chiari-like malformation and syringomyelia.
Topics: Amines; Analgesics; Animals; Arnold-Chiari Malformation; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dog Diseases; Dogs; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Male; Neuralgia; Prospective Studies; Quality of Life; Syringomyelia; Topiramate; Treatment Outcome | 2015 |
Electroacupuncture Versus Gabapentin for Hot Flashes Among Breast Cancer Survivors: A Randomized Placebo-Controlled Trial.
Topics: Adult; Aged; Amines; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Electroacupuncture; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Middle Aged; Needles; Survivors; Treatment Outcome | 2015 |
Effect of gabapentin pretreatment on the hemodynamic response to laryngoscopy and tracheal intubation in treated hypertensive patients.
Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Hemodynamics; Humans; Hypertension; Intubation, Intratracheal; Laryngoscopy; Male; Middle Aged | 2015 |
Treatment of Postherpetic Neuralgia With Gastroretentive Gabapentin: Interaction of Patient Demographics, Disease Characteristics, and Efficacy Outcomes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain Measurement; Sleep; Treatment Outcome; Young Adult | 2015 |
Randomized and controlled prospective trials of Ultrasound-guided spinal nerve posterior ramus pulsed radiofrequency treatment for lower back post-herpetic neuralgia.
Topics: Administration, Oral; Adult; Aged; Amines; Amitriptyline; Analgesics; Celecoxib; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Male; Middle Aged; Morphine; Neuralgia, Postherpetic; Pain Measurement; Prospective Studies; Pulsed Radiofrequency Treatment; Sleep; Spinal Nerves | 2015 |
The effect of gabapentin on muscle cramps during hemodialysis: A double-blind clinical trial.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Male; Middle Aged; Muscle Cramp; Renal Dialysis | 2015 |
Disambiguating Pharmacodynamic Efficacy from Behavior with Neuroimaging: Implications for Analgesic Drug Development.
Topics: Adult; Amines; Analgesics; Analgesics, Non-Narcotic; Brain; Capsaicin; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Ibuprofen; Magnetic Resonance Imaging; Male; Neuroimaging; Reproducibility of Results; Treatment Outcome; Young Adult | 2016 |
Attenuation of Hemodynamic Responses to Intubation by Gabapentin in Coronary Artery Bypass Surgery: a Randomized Clinical Trial.
Topics: Aged; Amines; Anesthesia, General; Blood Pressure; Coronary Artery Bypass; Cyclohexanecarboxylic Acids; Double-Blind Method; Elective Surgical Procedures; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Humans; Intubation, Intratracheal; Laryngoscopy; Middle Aged | 2015 |
Chemotherapy-induced nausea and vomiting: incidence and characteristics of persistent symptoms and future directions NCCTG N08C3 (Alliance).
Topics: Adult; Aged; Amines; Antiemetics; Antineoplastic Agents; Cisplatin; Cyclohexanecarboxylic Acids; Drug-Related Side Effects and Adverse Reactions; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Male; Middle Aged; Nausea; Neoplasms; Vomiting | 2016 |
The effect of tramadol and tramadol + gabapentin combination in patients with lumbar disc herniation after epidural steroid injection.
Topics: Administration, Oral; Adult; Amines; Analgesics; Anesthetics, Local; Bupivacaine; Cyclohexanecarboxylic Acids; Disability Evaluation; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Humans; Injections, Epidural; Intervertebral Disc Displacement; Low Back Pain; Lumbar Vertebrae; Male; Middle Aged; Prospective Studies; Single-Blind Method; Tramadol; Triamcinolone Acetonide; Visual Analog Scale | 2015 |
Efficacy of low dose gabapentin in acute herpes zoster for preventing postherpetic neuralgia: a prospective controlled study.
Topics: Acetaminophen; Acyclovir; Aged; Aged, 80 and over; Amines; Analgesics; Analgesics, Non-Narcotic; Antiviral Agents; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain Measurement; Prospective Studies; Quality of Life; Republic of Korea; Time Factors; Treatment Outcome; Valacyclovir; Valine | 2016 |
Clinical Trial Assessing the Efficacy of Gabapentin Plus B Complex (B1/B12) versus Pregabalin for Treating Painful Diabetic Neuropathy.
Topics: Adolescent; Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Combinations; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Pregabalin; Thiamine; Visual Analog Scale; Vitamin B 12 | 2016 |
Pilot trial of gabapentin for the treatment of benzodiazepine abuse or dependence in methadone maintenance patients.
Topics: Adolescent; Adult; Aged; Amines; Benzodiazepines; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Methadone; Middle Aged; Opiate Substitution Treatment; Pilot Projects; Psychotherapy; Substance Withdrawal Syndrome; Substance-Related Disorders; Young Adult | 2016 |
A randomized controlled trial of gabapentin for chronic low back pain with and without a radiating component.
Topics: Adult; Aged; Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Disability Evaluation; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Male; Middle Aged; Pain Measurement; Treatment Outcome | 2016 |
Randomized trial of standard pain control with or without gabapentin for pain related to radiation-induced mucositis in head and neck cancer.
Topics: Acetaminophen; Adult; Aged; Amines; Analgesics; Analgesics, Opioid; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Head and Neck Neoplasms; Humans; Male; Middle Aged; Pain; Pain Management; Radiation Injuries; Radiotherapy; Squamous Cell Carcinoma of Head and Neck; Stomatitis | 2016 |
Addressing challenges of clinical trials in acute pain: The Pain Management of Vaso-occlusive Crisis in Children and Young Adults with Sickle Cell Disease Study.
Topics: Acute Disease; Acute Pain; Adolescent; Adult; Amines; Analgesics; Anemia, Sickle Cell; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Male; Pain Management; Pain Measurement; Research Design; Young Adult | 2016 |
Next-day residual effects of gabapentin, diphenhydramine, and triazolam on simulated driving performance in healthy volunteers: a phase 3, randomized, double-blind, placebo-controlled, crossover trial.
Topics: Adult; Amines; Analgesics; Anti-Anxiety Agents; Automobile Driving; Cognition; Cross-Over Studies; Cyclohexanecarboxylic Acids; Diphenhydramine; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Male; Middle Aged; Sleep Stages; Time Factors; Triazolam | 2016 |
Relationship between pain relief, reduction in pain-associated sleep interference, and overall impression of improvement in patients with postherpetic neuralgia treated with extended-release gabapentin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain Management; Pain Measurement; Prevalence; Quality of Life; Sleep; Treatment Outcome; Young Adult | 2016 |
Gabapentin Superadded to a Pre-Existent Regime Containing Amytriptyline for Chronic Sciatica.
Topics: Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Chronic Disease; Cohort Studies; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Prospective Studies; Sciatica; Young Adult | 2016 |
Gabapentin: A promising therapy for uremic pruritus in hemodialysis patients: A randomized-controlled trial and review of literature.
Topics: Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pruritus; Renal Dialysis; Uremia | 2016 |
Gabapentin for the Management of Chronic Pelvic Pain in Women (GaPP1): A Pilot Randomised Controlled Trial.
Topics: Adolescent; Adult; Amines; Analgesics; Chronic Pain; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Statistical; Outcome Assessment, Health Care; Pain Management; Pelvic Pain; Pilot Projects; Prospective Studies; Young Adult | 2016 |
Arthroscopic bankart surgery: Does gabapentin reduce postoperative pain and opioid consumption? A triple-blinded randomized clinical trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amines; Analgesics; Analgesics, Opioid; Arthroscopy; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Preoperative Care; Shoulder Joint; Young Adult | 2016 |
A Validated Fluorometric Method for the Rapid Determination of Pregabalin in Human Plasma Applied to Patients With Pain.
Topics: Amines; Analgesics; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Data Accuracy; Fluorometry; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Pain; Pregabalin; Reference Standards | 2016 |
Comparative pre-emptive analgesic efficacy study of novel antiepileptic agents gabapentin, lamotrigine and topiramate in patients undergoing major surgeries at a tertiary care hospital: a randomized double blind clinical trial.
Topics: Adolescent; Adult; Aged; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Pain, Postoperative; Preoperative Care; Tertiary Care Centers; Topiramate; Treatment Outcome; Triazines; Young Adult | 2017 |
Adjunctive pregabalin vs gabapentin for focal seizures: Interpretation of comparative outcomes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pregabalin; Seizures; Treatment Outcome; Young Adult | 2016 |
The Effectiveness of Oral Corticosteroids for Management of Lumbar Radiating Pain: Randomized, Controlled Trial Study.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Lumbosacral Region; Male; Middle Aged; Patient Satisfaction; Pregabalin; Quality of Life; Radiculopathy; Surveys and Questionnaires; Young Adult | 2016 |
Role of gabapentin and anticholinergics in management of neurogenic bladder after repair of spina bifida - a randomized controlled study.
Topics: Adolescent; Amines; Child; Child, Preschool; Cholinergic Antagonists; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mandelic Acids; Prospective Studies; Spinal Dysraphism; Urinary Bladder, Neurogenic; Urological Agents; Young Adult | 2016 |
The research on long-term clinical effects and patients' satisfaction of gabapentin combined with oxycontin in treatment of severe cancer pain.
Topics: Adult; Amines; Analgesics; Cancer Pain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Narcotics; Oxycodone; Pain Measurement; Patient Satisfaction; Prospective Studies; Severity of Illness Index; Treatment Outcome | 2016 |
Comparative effectiveness of electro-acupuncture versus gabapentin for sleep disturbances in breast cancer survivors with hot flashes: a randomized trial.
Topics: Acupuncture Therapy; Adult; Aged; Amines; Anti-Anxiety Agents; Breast Neoplasms; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Middle Aged; Postmenopause; Sleep Wake Disorders; Treatment Outcome | 2017 |
Phantom motor execution facilitated by machine learning and augmented reality as treatment for phantom limb pain: a single group, clinical trial in patients with chronic intractable phantom limb pain.
Topics: Adult; Aged; Amines; Amputation, Surgical; Chronic Pain; Cyclohexanecarboxylic Acids; Exercise Therapy; Gabapentin; Games, Recreational; gamma-Aminobutyric Acid; Humans; Machine Learning; Middle Aged; Pain Measurement; Phantom Limb; Slovenia; Sweden; Treatment Outcome; Upper Extremity; Virtual Reality Exposure Therapy | 2016 |
Efficacy of gabapentin for prevention of postherpetic neuralgia: study protocol for a randomized controlled clinical trial.
Topics: Acyclovir; Amines; Analgesics; Antiviral Agents; Clinical Protocols; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain Measurement; Quality of Life; Research Design; Sleep; Spain; Surveys and Questionnaires; Time Factors; Treatment Outcome; Valacyclovir; Valine | 2017 |
Gabapentin acutely increases the apnea-hypopnea index in older men: data from a randomized, double-blind, placebo-controlled study.
Topics: Adult; Aged; Amines; Anticonvulsants; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pilot Projects; Polysomnography; Respiration; Sleep | 2017 |
Efficacy and Safety of Gabapentin in Comparison to Solifenacin Succinate in Adult Overactive Bladder Treatment.
Topics: Adolescent; Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Muscarinic Antagonists; Prospective Studies; Quality of Life; Solifenacin Succinate; Treatment Outcome; Urinary Bladder, Overactive; Urological Agents; Young Adult | 2018 |
Botulinum Toxin Treatment for Nocturnal Calf Cramps in Patients With Lumbar Spinal Stenosis: A Randomized Clinical Trial.
Topics: Aged; Amines; Analgesics; Botulinum Toxins, Type A; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lumbar Vertebrae; Male; Middle Aged; Neuromuscular Agents; Pain Management; Patient Acuity; Prospective Studies; Sleep-Wake Transition Disorders; Spinal Stenosis | 2017 |
Gabapentin Does Not Appear to Improve Postoperative Pain and Sleep Patterns in Patients Who Concomitantly Receive Regional Anesthesia for Lower Extremity Orthopedic Surgery: A Randomized Control Trial.
Topics: Adolescent; Adult; Aged; Amines; Analgesics; Arthroplasty, Replacement; Celecoxib; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lower Extremity; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Sleep Wake Disorders; Statistics, Nonparametric; Surveys and Questionnaires; Treatment Outcome; Young Adult | 2017 |
The comparative preemptive analgesic efficacy of addition of vitamin B complex to gabapentin versus gabapentin alone in women undergoing cesarean section under spinal anesthesia: A prospective randomized double-blind study.
Topics: Administration, Oral; Adult; Amines; Analgesics; Anesthesia, Spinal; Cesarean Section; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Pregnancy; Preoperative Care; Prospective Studies; Treatment Outcome; Vitamin B Complex | 2017 |
Combination of gabapentin and ramosetron for the prevention of postoperative nausea and vomiting after gynecologic laparoscopic surgery: a prospective randomized comparative study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, General; Antiemetics; Benzimidazoles; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Gynecologic Surgical Procedures; Humans; Laparoscopy; Middle Aged; Postoperative Nausea and Vomiting; Prospective Studies; Young Adult | 2017 |
Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Celecoxib; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Utilization; Female; Gabapentin; gamma-Aminobutyric Acid; Gynecologic Surgical Procedures; Humans; Ibuprofen; Intraoperative Care; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Care; Premedication | 2017 |
Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial.
Topics: Aged; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Delirium; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Length of Stay; Male; Perioperative Care; Postoperative Complications | 2017 |
Gabapentin in the Management of Pain following Tonsillectomy: A Randomized Double-Blind Placebo-Controlled Trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; New Zealand; Pain Management; Pain Measurement; Pain, Postoperative; Prospective Studies; Tonsillectomy; Treatment Outcome | 2017 |
Multi-kinetics and site-specific release of gabapentin and flurbiprofen from oral fixed-dose combination: in vitro release and in vivo food effect.
Topics: Administration, Oral; Adolescent; Adult; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Drug Combinations; Drug Liberation; Female; Flurbiprofen; Food-Drug Interactions; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Middle Aged; Polymers; Tablets; Young Adult | 2017 |
A randomized controlled trial of amitriptyline versus gabapentin for complex regional pain syndrome type I and neuropathic pain in children.
Topics: Adolescent; Amines; Amitriptyline; Analgesics; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Reflex Sympathetic Dystrophy | 2016 |
Study protocol for a multi-institutional, randomised, double-blinded, placebo-controlled phase III trial investigating additive efficacy of duloxetine for neuropathic cancer pain refractory to opioids and gabapentinoids: the DIRECT study.
Topics: Adult; Aged; Amines; Analgesics; Analgesics, Opioid; Cancer Pain; Cyclohexanecarboxylic Acids; Double-Blind Method; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Neoplasms; Neuralgia; Research Design; Young Adult | 2017 |
Effects of premedication with oral gabapentin on intraocular pressure changes following tracheal intubation in clinically normal dogs.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dogs; Gabapentin; gamma-Aminobutyric Acid; Intraocular Pressure; Intubation, Intratracheal; Premedication | 2017 |
Evaluation of Acupuncture in the Treatment of Restless Legs Syndrome: A Randomized Controlled Trial.
Topics: Acupuncture Therapy; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Restless Legs Syndrome; Treatment Outcome | 2017 |
Perioperative Gabapentin Improves Patient-Centered Outcomes After Inguinal Hernia Repair.
Topics: Adjuvants, Anesthesia; Adult; Amines; Androstanols; Anesthetics, Local; Antiemetics; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Hernia, Inguinal; Humans; Hypnotics and Sedatives; Lidocaine; Male; Midazolam; Middle Aged; Neuromuscular Depolarizing Agents; Ondansetron; Placebos; Plastic Surgery Procedures; Propofol; Quality of Life; Rocuronium; Succinylcholine; Treatment Outcome | 2017 |
Effects of a single preappointment dose of gabapentin on signs of stress in cats during transportation and veterinary examination.
Topics: Amines; Animal Welfare; Animals; Anxiety; Behavior, Animal; Cats; Cross-Over Studies; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Physical Examination; Stress, Physiological; Transportation | 2017 |
Fibromyalgia with Gabapentin and Osteopathic Manipulative Medicine: A Pilot Study.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Manipulation, Osteopathic; Middle Aged; Pilot Projects | 2018 |
Optimizing the dose of local infiltration analgesia and gabapentin for total knee arthroplasty, a randomized single blind trial in 128 patients.
Topics: Aged; Aged, 80 and over; Amides; Amines; Analgesics; Anesthetics, Local; Arthroplasty, Replacement, Knee; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Length of Stay; Male; Middle Aged; Pain, Postoperative; Prospective Studies; Ropivacaine; Single-Blind Method | 2018 |
GaPP2, a multicentre randomised controlled trial of the efficacy of gabapentin for the management of chronic pelvic pain in women: study protocol.
Topics: Adolescent; Adult; Amines; Analgesics; Chronic Disease; Chronic Pain; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain Management; Pain Measurement; Pelvic Pain; Pilot Projects; Research Design; Surveys and Questionnaires; Treatment Outcome; Young Adult | 2018 |
Gabapentin pretreatment for propofol and rocuronium injection pain: A randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesics; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Male; Middle Aged; Neuromuscular Nondepolarizing Agents; Pain Measurement; Pain, Procedural; Propofol; Prospective Studies; Rocuronium; Young Adult | 2018 |
Gabapentine 300 mg vs. 450 mg as anesthetic premedication for reactive hypertension, anxiety and analgesia
Topics: Amines; Analgesia; Analgesics; Anti-Anxiety Agents; Anxiety; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Premedication; White Coat Hypertension | 2018 |
Gabapentin dose and the 30-day risk of altered mental status in older adults: A retrospective population-based study.
Topics: Aged; Aged, 80 and over; Amines; Confusion; Cyclohexanecarboxylic Acids; Disease-Free Survival; Dizziness; Female; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Male; Neuralgia; Retrospective Studies; Risk Factors; Sleep Stages; Survival Rate; Tomography, X-Ray Computed | 2018 |
Pharmacokinetics of immediate release, extended release, and gastric retentive gabapentin formulations in healthy adults
.
Topics: Administration, Oral; Adult; Amines; Analgesics; Biological Availability; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Drug Compounding; Drug Monitoring; Female; Gabapentin; gamma-Aminobutyric Acid; Healthy Volunteers; Humans; Male; Middle Aged; Models, Biological; Therapeutic Equivalency | 2018 |
Effects of gabapentin, pregabalin and gastroretentive gabapentin on simulated driving, daytime sedation and cognition.
Topics: Adult; Amines; Analgesics; Attention; Automobile Driving; Cognition; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Healthy Volunteers; Humans; Learning; Male; Pregabalin; Psychomotor Performance; Tremor; Wakefulness | 2018 |
Preemptive Analgesia Decreases Pain Following Anorectal Surgery: A Prospective, Randomized, Double-Blinded, Placebo-Controlled Trial.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Amines; Anal Canal; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Anus Diseases; Condylomata Acuminata; Cyclohexanecarboxylic Acids; Dexamethasone; Digestive System Surgical Procedures; Double-Blind Method; Female; Fissure in Ano; Gabapentin; gamma-Aminobutyric Acid; Hemorrhoidectomy; Hemorrhoids; Humans; Hydromorphone; Ibuprofen; Ketamine; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Rectal Fistula; Rectum | 2018 |
Effects of Gabapentinoids Premedication on Shoulder Pain and Rehabilitation Quality after Laparoscopic Cholecystectomy: Pregabalin versus Gabapentin.
Topics: Adult; Analgesics; Cholecystectomy; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain, Postoperative; Pregabalin; Shoulder Pain; Treatment Outcome | 2018 |
Perioperative Gabapentin in Pediatric Thoracic Surgery Patients-Randomized, Placebo-Controlled, Phase 4 Trial.
Topics: Adolescent; Amines; Analgesics; Analgesics, Opioid; Child; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Pain, Postoperative; Thoracic Surgery | 2020 |
The Clinical Difference between Gabapentin and Pregabalin: Data from a Pilot Comparative Trial.
Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pilot Projects; Pregabalin | 2021 |
Effects of Gabapentin on Dorsal Anterior Cingulate Cortex GABA and Glutamate Levels and Their Associations With Abstinence in Alcohol Use Disorder: A Randomized Clinical Trial.
Topics: Adult; Alcoholism; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Substance Withdrawal Syndrome | 2021 |
Results from a randomized, double-blind, placebo-controlled, crossover, multimodal-MRI pilot study of gabapentin for co-occurring bipolar and cannabis use disorders.
Topics: Adolescent; Adult; Bipolar Disorder; Cigarette Smoking; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Marijuana Abuse; Middle Aged; Pilot Projects; Proton Magnetic Resonance Spectroscopy; Young Adult | 2022 |
Comparison the effect of valerian and gabapentin on RLS and sleep quality in hemodialysis patients: A randomized clinical trial.
Topics: Gabapentin; gamma-Aminobutyric Acid; Humans; Renal Dialysis; Restless Legs Syndrome; Sleep Quality; Valerian | 2023 |
Effectiveness of oral clonidine and gabapentin on peripheral neuropathy in diabetic patients in southwestern Iran: a randomized clinical trial.
Topics: Amines; Analgesics; Clonidine; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Humans; Iran; Neuralgia | 2023 |
1943 other study(ies) available for gabapentin and gamma-aminobutyric acid
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Stability studies of gabapentin in aqueous solutions.
Topics: Acetates; Amines; Anticonvulsants; Buffers; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Osmolar Concentration; Solutions; Temperature; Water | 1992 |
Alpha 2u-globulin nephropathy without nephrocarcinogenesis in male Wistar rats administered 1-(aminomethyl)cyclohexaneacetic acid.
Topics: Acetates; Alpha-Globulins; Amines; Animals; Chromatography, Gel; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Glomerulonephritis; Immunohistochemistry; Kidney Diseases; Kidney Neoplasms; Kidney Tubules, Proximal; Male; Organ Size; Rats; Rats, Inbred Strains | 1991 |
Comparison of gabapentin with other antiepileptic and GABAergic drugs.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Carbamazepine; Cats; Cyclohexanecarboxylic Acids; Electric Stimulation; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Injections, Intravenous; Maxillary Nerve; Phenytoin; Reaction Time; Trigeminal Nuclei | 1991 |
Gabapentin increases aminooxyacetic acid-induced GABA accumulation in several regions of rat brain.
Topics: Acetates; Amines; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain Chemistry; Cyclohexanecarboxylic Acids; Electroshock; Female; Gabapentin; gamma-Aminobutyric Acid; Rats; Rats, Inbred Strains; Seizures | 1991 |
Intestinal absorption of gabapentin in rats.
Topics: Acetates; Amines; Animals; Biological Transport, Active; Cyclohexanecarboxylic Acids; Diffusion; Female; Gabapentin; gamma-Aminobutyric Acid; Intestinal Absorption; Rats | 1991 |
Lack of a pharmacokinetic interaction between phenobarbitone and gabapentin.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Phenobarbital | 1991 |
Determination of gabapentin in plasma and urine by capillary column gas chromatography.
Topics: Acetates; Amines; Chromatography, Gas; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans | 1990 |
Mechanisms of action of new antiepileptic drugs.
Topics: Acetamides; Acetates; Amines; Aminocaproates; Aminopyridines; Anti-Anxiety Agents; Anticonvulsants; Aspartic Acid; Benzodiazepines; Benzodiazepinones; Clobazam; Cyclohexanecarboxylic Acids; Dibenzocycloheptenes; Dizocilpine Maleate; Epilepsy; Felbamate; Flumazenil; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Imidazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Receptors, GABA-A; Triazines; Vigabatrin | 1989 |
Gabapentin augments whole blood serotonin in healthy young men.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Melatonin; Reference Values; Serotonin; Sleep; Sleep, REM | 1988 |
Pharmacokinetics and metabolism of gabapentin in rat, dog and man.
Topics: Acetates; Adult; Amines; Animals; Biotransformation; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dogs; Erythrocytes; Feces; Female; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Kinetics; Male; Protein Binding; Rats; Rats, Inbred Strains; Species Specificity; Tissue Distribution | 1986 |
Determination of gabapentin in plasma and urine by high-performance liquid chromatography and pre-column labelling for ultraviolet detection.
Topics: Acetates; Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Kinetics; Microchemistry; Spectrophotometry, Ultraviolet; Trinitrobenzenesulfonic Acid | 1985 |
Gabapentin decreases monoamine release without affecting acetylcholine release in the brain.
Topics: Acetates; Acetylcholine; Amines; Animals; Caudate Nucleus; Cerebral Cortex; Cyclohexanecarboxylic Acids; Electric Stimulation; Female; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Norepinephrine; Rabbits; Rats; Rats, Inbred Strains; Serotonin | 1985 |
Inhibition by GABA, baclofen and gabapentin of dopamine release from rabbit caudate nucleus: are there common or different sites of action?
Topics: Acetates; Amines; Animals; Baclofen; Bicuculline; Binding Sites; Caudate Nucleus; Cyclohexanecarboxylic Acids; Dopamine; Female; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Nipecotic Acids; Rabbits | 1983 |
Gabapentin actions on ligand- and voltage-gated responses in cultured rodent neurons.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Calcium Channels; Cells, Cultured; Cerebral Cortex; Cyclohexanecarboxylic Acids; Fetus; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ion Channel Gating; Ion Channels; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Neurons, Afferent; Nodose Ganglion; Rats; Sodium Channels; Spinal Cord; Synapses | 1993 |
Determination of gabapentin in serum by capillary electrophoresis.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Electrophoresis, Capillary; Gabapentin; gamma-Aminobutyric Acid; Humans; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1995 |
Disposition of gabapentin (neurontin) in mice, rats, dogs, and monkeys.
Topics: Acetates; Administration, Oral; Amines; Animals; Anticonvulsants; Autoradiography; Biological Availability; Biotransformation; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dogs; Female; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Injections, Intravenous; Macaca fascicularis; Male; Mice; Protein Binding; Rats; Rats, Sprague-Dawley; Species Specificity; Tissue Distribution | 1995 |
Gabapentin in the management of reflex sympathetic dystrophy.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Reflex Sympathetic Dystrophy | 1995 |
The role of newer anticonvulsants in the management of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Australia; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Vigabatrin | 1995 |
New drugs for the treatment of epilepsy.
Topics: Acetates; Amines; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines | 1995 |
Hypomania induced by gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy, Complex Partial; Epilepsy, Tonic-Clonic; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 1995 |
Optimized method for determination of gabapentin in serum by high-performance liquid chromatography.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration | 1995 |
Gabapentin--a new antiepileptic drug.
Topics: Acetates; Aged; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Seizures | 1994 |
Gabapentin for behavioral dyscontrol.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mental Disorders | 1995 |
Disposition of gabapentin in anuric subjects on hemodialysis.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Aged; Amines; Anticonvulsants; Anuria; Cyclohexanecarboxylic Acids; Dialysis Solutions; Female; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Renal Dialysis | 1995 |
Transport of gabapentin, a gamma-amino acid drug, by system l alpha-amino acid transporters: a comparative study in astrocytes, synaptosomes, and CHO cells.
Topics: Acetates; Amines; Amino Acid Transport Systems; Amino Acids; Animals; Arginine; Astrocytes; Binding, Competitive; Biological Transport; Carrier Proteins; CHO Cells; Cricetinae; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Kinetics; Leucine; Male; Rats; Rats, Sprague-Dawley; Synaptosomes | 1995 |
Gabapentin (NEURONTIN)--a novel anticonvulsant.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1994 |
Pancreatic acinar cell neoplasia in male Wistar rats following 2 years of gabapentin exposure.
Topics: Acetates; Adenoma; Amines; Animals; Anticonvulsants; Carcinoma, Acinar Cell; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Pancreatic Neoplasms; Rats; Rats, Wistar; Sex Factors; Time Factors | 1995 |
Gabapentin treatment of seizures in acute intermittent porphyria.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Porphyria, Acute Intermittent | 1995 |
Neurontin--1 year on. London October 1994.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Product Surveillance, Postmarketing; Treatment Outcome; United Kingdom; United States | 1995 |
Gabapentin potentiates the conductance increase induced by nipecotic acid in CA1 pyramidal neurons in vitro.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Synergism; Electric Conductivity; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Nipecotic Acids; Patch-Clamp Techniques; Proline; Pyramidal Cells; Rats; Rats, Wistar | 1995 |
Successful treatment of reflex sympathetic dystrophy with gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Reflex Sympathetic Dystrophy; Treatment Outcome | 1995 |
New antiepileptic medications.
Topics: 4-Aminobutyrate Transaminase; Acetamides; Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Tiagabine; Triazines; Vigabatrin | 1995 |
Developmental toxicity studies in mice, rats, and rabbits with the anticonvulsant gabapentin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Embryonic and Fetal Development; Female; Gabapentin; gamma-Aminobutyric Acid; Intubation, Gastrointestinal; Litter Size; Male; Mice; Mice, Inbred Strains; Rabbits; Rats; Rats, Inbred Strains | 1994 |
Absence of Ki-ras mutations in exocrine pancreatic tumors from male rats chronically exposed to gabapentin.
Topics: Acetates; Adenocarcinoma; Adenoma; Amines; Animals; Base Sequence; Codon; Cyclohexanecarboxylic Acids; DNA, Neoplasm; Gabapentin; gamma-Aminobutyric Acid; Genes, ras; Hyperplasia; Male; Molecular Sequence Data; Pancreas; Pancreatic Neoplasms; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins p21(ras); Rats; Rats, Wistar | 1995 |
Successful treatment of seizures and porphyria with gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Porphyria Cutanea Tarda; Seizures | 1995 |
Interaction of gabapentin with other antiepileptics.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Phenytoin | 1994 |
Gabapentin as add-on therapy for refractory partial epilepsy: results of five placebo-controlled trials.
Topics: Acetates; Amines; Anticonvulsants; Clinical Trials as Topic; Confidence Intervals; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Drugs, Investigational; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Multicenter Studies as Topic; Placebos | 1994 |
Gabapentin increases GABA-induced depolarization in rat neonatal optic nerve.
Topics: Acetates; Action Potentials; Amines; Animals; Animals, Newborn; Anticonvulsants; Bicuculline; Cyclohexanecarboxylic Acids; GABA-A Receptor Antagonists; Gabapentin; gamma-Aminobutyric Acid; Membrane Potentials; Neuromuscular Depolarizing Agents; Nipecotic Acids; Optic Nerve; Proline; Rats; Rats, Wistar; Receptors, GABA-A | 1994 |
FDA approved new drug bulletin. Gabapentin (neurontin).
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Patient Education as Topic; Pregnancy; United States; United States Food and Drug Administration | 1994 |
Pharmacokinetics of gabapentin in subjects with various degrees of renal function.
Topics: Acetates; Administration, Oral; Adolescent; Adult; Aged; Amines; Creatinine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Diseases; Male; Middle Aged; Renal Insufficiency | 1994 |
Novel antiepileptic drugs: nursing implications.
Topics: Acetates; Amines; Aminocaproates; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Approval; Drug Interactions; Drug Monitoring; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Patient Care Planning; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin | 1993 |
Gabapentin anticonvulsant action in rats: disequilibrium with peak drug concentrations in plasma and brain microdialysate.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Microdialysis; Rats; Rats, Sprague-Dawley | 1993 |
Gabapentin--a new anticonvulsant.
Topics: Acetates; Amines; Animals; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 1994 |
Limitation by gabapentin of high frequency action potential firing by mouse central neurons in cell culture.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Cells, Cultured; Cerebral Cortex; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Membrane Potentials; Mice; Neurons; Refractory Period, Electrophysiological; Spinal Cord | 1994 |
Lack of serious toxicity following gabapentin overdose.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Overdose; Female; Gabapentin; gamma-Aminobutyric Acid; Humans | 1994 |
Science reporters hear wide range of recent data at 12th annual conference.
Topics: Acetates; Aged; AIDS Vaccines; American Medical Association; Amines; Animals; Anticonvulsants; beta-Cyclodextrins; Cells, Cultured; Clinical Trials as Topic; Cochlear Implants; Complementary Therapies; Constriction, Pathologic; Coronary Artery Bypass; Cyclodextrins; Cyclohexanecarboxylic Acids; Depressive Disorder; Drug Therapy, Combination; Epilepsy; Extracorporeal Membrane Oxygenation; Felbamate; Fetus; Gabapentin; gamma-Aminobutyric Acid; Genetic Therapy; Health Care Costs; HIV Infections; Humans; Hyperlipoproteinemia Type II; Lamotrigine; Muscle, Smooth; National Institutes of Health (U.S.); Oxygen; Phenylcarbamates; Propylene Glycols; Respiration, Artificial; Respiratory Distress Syndrome; Triazines; United States; Vascular Surgical Procedures | 1993 |
[3H]gabapentin may label a system-L-like neutral amino acid carrier in brain.
Topics: Acetates; Amines; Amino Acids; Animals; Binding, Competitive; Brain Chemistry; Carrier Proteins; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Protein Binding; Swine; Synaptic Membranes | 1993 |
Potent and stereospecific anticonvulsant activity of 3-isobutyl GABA relates to in vitro binding at a novel site labeled by tritiated gabapentin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Binding, Competitive; Cerebral Cortex; Cyclohexanecarboxylic Acids; Electroshock; Gabapentin; gamma-Aminobutyric Acid; Injections, Intravenous; Male; Mice; Pregabalin; Receptors, GABA-A; Stereoisomerism; Synaptic Membranes | 1993 |
Characterisation of [3H]gabapentin binding to a novel site in rat brain: homogenate binding studies.
Topics: Acetates; Amines; Amino Acids; Animals; Anticonvulsants; Baclofen; Binding Sites; Cell Membrane; Cerebral Cortex; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Rats; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine | 1993 |
Localization of [3H]gabapentin to a novel site in rat brain: autoradiographic studies.
Topics: Acetates; Amines; Animals; Anticonvulsants; Autoradiography; Binding Sites; Brain; Cerebral Cortex; Corpus Striatum; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; Quinolinic Acid; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1993 |
Effects of gabapentin on release of gamma-aminobutyric acid from slices of rat neostriatum.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Neostriatum; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A | 1993 |
A saturable transport mechanism in the intestinal absorption of gabapentin is the underlying cause of the lack of proportionality between increasing dose and drug levels in plasma.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glycine; Humans; In Vitro Techniques; Intestinal Absorption; Leucine; Male; Perfusion; Permeability; Phenylalanine; Rats; Rats, Wistar | 1993 |
New antiepileptic medications.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroencephalography; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines | 1995 |
The anticonvulsant gabapentin enhances promoted release of GABA in hippocampus: a field potential analysis.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Electrophysiology; Extracellular Space; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Microinjections; Nipecotic Acids; Proline; Pyramidal Cells; Rats; Rats, Wistar | 1995 |
Costing of antiepileptic drugs.
Topics: Acetates; Amines; Anticonvulsants; Argentina; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Costs; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin | 1996 |
Effects of anticonvulsant drug gabapentin on the enzymes in metabolic pathways of glutamate and GABA.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Cytosol; Gabapentin; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; In Vitro Techniques; Kinetics; Male; Mitochondria; Rats; Rats, Sprague-Dawley; Synaptosomes; Transaminases | 1995 |
Potential treatment of amyotrophic lateral sclerosis with gabapentin: a hypothesis.
Topics: Acetates; Amines; Amino Acids, Branched-Chain; Amyotrophic Lateral Sclerosis; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Humans | 1995 |
[Gabapentin--a new add-on antiepileptic drug].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1996 |
[Current role of novel antiepileptics in the treatment of epilepsies].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Resistance; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin | 1996 |
[Recommendations on clinical epilepsy treatment using gabapentin].
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Child; Contraindications; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1996 |
Behavioral side effects of gabapentin in children.
Topics: Acetates; Aggression; Akathisia, Drug-Induced; Amines; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Child, Preschool; Comorbidity; Cyclohexanecarboxylic Acids; Developmental Disabilities; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 1996 |
Restless legs syndrome.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Restless Legs Syndrome | 1996 |
Gabapentin associated with aggressive behavior in pediatric patients with seizures.
Topics: Acetates; Adolescent; Age Factors; Aggression; Amines; Anticonvulsants; Child; Child Behavior Disorders; Cyclohexanecarboxylic Acids; Epilepsy, Complex Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Male; Seizures | 1996 |
Choreoathetotic movements: A possible side effect of gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Athetosis; Chorea; Cyclohexanecarboxylic Acids; Dyskinesia, Drug-Induced; Epilepsies, Partial; Facial Muscles; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Movement | 1996 |
Exacerbation of seizures in Lennox-Gastaut syndrome by gabapentin.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Male; Syndrome | 1996 |
The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel.
Topics: Acetates; Amines; Animals; Anticonvulsants; Calcium Channels; Cell Line; Cell Membrane; Cerebral Cortex; Chlorocebus aethiops; Chromatography; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Cyclohexanecarboxylic Acids; DNA, Complementary; Durapatite; Electrophoresis, Polyacrylamide Gel; Gabapentin; gamma-Aminobutyric Acid; Kinetics; Macromolecular Substances; Molecular Weight; Muscle, Skeletal; Rabbits; Recombinant Proteins; Swine; Transfection; Tritium | 1996 |
Epilepsy in porphyria.
Topics: 5-Aminolevulinate Synthetase; Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease-Free Survival; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Heme; Humans; Liver; Male; Porphyrias; Porphyrias, Hepatic | 1996 |
Postpoliomyelitis pain treated with gabapentin.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain; Postpoliomyelitis Syndrome | 1996 |
Efficacy of gabapentin therapy in children with refractory partial seizures.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Child; Child Behavior; Child, Preschool; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Male; Treatment Outcome | 1996 |
Antimyoclonic effect of gabapentin in a posthypoxic animal model of myoclonus.
Topics: Acetates; Acoustic Stimulation; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; DDT; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hypoxia; Male; Myoclonus; Rats; Rats, Sprague-Dawley; Seizures | 1996 |
[New medical treatment of epilepsy].
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Costs; Epilepsy; France; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Middle Aged; Triazines; Vigabatrin | 1996 |
The simultaneous estimation of the influx and efflux blood-brain barrier permeabilities of gabapentin using a microdialysis-pharmacokinetic approach.
Topics: Acetates; Amines; Animals; Anticonvulsants; Blood-Brain Barrier; Brain; Brain Chemistry; Cyclohexanecarboxylic Acids; Dialysis; Gabapentin; gamma-Aminobutyric Acid; Male; Permeability; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 1996 |
Gabapentin, valproic acid, and ethanol intoxication: elevated blood levels with mild clinical effects.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Overdose; Ethanol; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Seizures; Suicide, Attempted; Valproic Acid | 1996 |
Management of restless legs syndrome with gabapentin (Neurontin)
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Restless Legs Syndrome; Treatment Outcome | 1996 |
Add-on gabapentin for refractory seizures in patients with brain tumours.
Topics: Acetates; Amines; Anticonvulsants; Brain Neoplasms; Cyclohexanecarboxylic Acids; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Seizures | 1996 |
Reduction of fasciculations in patients with amyotrophic lateral sclerosis with the use of gabapentin.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Anticonvulsants; Cyclohexanecarboxylic Acids; Fasciculation; Gabapentin; gamma-Aminobutyric Acid; Humans | 1996 |
Comparison of the uptake of [3H]-gabapentin with the uptake of L-[3H]-leucine into rat brain synaptosomes.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Leucine; Rats; Synaptosomes; Temperature; Time Factors | 1996 |
Comparison of the autoradiographic binding distribution of [3H]-gabapentin with excitatory amino acid receptor and amino acid uptake site distributions in rat brain.
Topics: Acetates; Amines; Amino Acids; Animals; Anticonvulsants; Autoradiography; Binding, Competitive; Brain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Rats; Receptors, Amino Acid; Tissue Distribution | 1996 |
Gabapentin for the treatment of hemifacial spasm.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Facial Nerve Diseases; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Spasm | 1996 |
Gabapentin as a novel treatment for postherpetic neuralgia.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia | 1996 |
An audit of the new antiepileptic drugs in clinical neurological practice.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Treatment Outcome; Triazines; Vigabatrin | 1996 |
Effects of antiepileptic drugs on motor cortex excitability in humans: a transcranial magnetic stimulation study.
Topics: 4-Aminobutyrate Transaminase; Acetates; Adult; Amines; Anticonvulsants; Baclofen; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Differential Threshold; Enzyme Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Motor Cortex; Physical Stimulation; Transcranial Magnetic Stimulation; Vigabatrin | 1996 |
Determination of gabapentin in plasma by high-performance liquid chromatography.
Topics: Acetates; Amines; Amino Acids; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Quality Control; Sensitivity and Specificity | 1996 |
Movement disorders associated with the use of gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Benzodiazepines; Cyclohexanecarboxylic Acids; Dyskinesia, Drug-Induced; Dystonia; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lorazepam; Male; Myoclonus; Ocular Motility Disorders | 1996 |
Hypomania induced by gabapentin.
Topics: Acetates; Affect; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Electroencephalography; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Learning Disabilities | 1995 |
Weight gain and gabapentin therapy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Weight Gain | 1995 |
Gabapentin interaction with felbamate.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Phenylcarbamates; Propylene Glycols | 1996 |
The antiepileptic agent gabapentin (Neurontin) possesses anxiolytic-like and antinociceptive actions that are reversed by D-serine.
Topics: Acetates; Amines; Analgesics; Animals; Anti-Anxiety Agents; Callithrix; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Pain Measurement; Rats; Rats, Wistar; Serine | 1996 |
Determination of gabapentin in serum using solid-phase extraction and gas-liquid chromatography.
Topics: Acetamides; Acetates; Amines; Anticonvulsants; Calibration; Chromatography, Gas; Cycloheptanes; Cyclohexanecarboxylic Acids; Flame Ionization; Fluoroacetates; Gabapentin; gamma-Aminobutyric Acid; Humans; Organosilicon Compounds; Reference Standards; Reproducibility of Results; Silanes; Trifluoroacetic Acid | 1996 |
Long-term consequences of subtle stimuli during the first twenty-four hours of seizure-induced brain injury.
Topics: Acetates; Amines; Animals; Anticonvulsants; Appetitive Behavior; Brain Damage, Chronic; Cholinergic Fibers; Cyclohexanecarboxylic Acids; Dominance, Cerebral; Electromagnetic Fields; Gabapentin; gamma-Aminobutyric Acid; Limbic System; Lithium; Male; Maze Learning; Mental Recall; Pilocarpine; Prednisolone; Rats; Seizures | 1996 |
If comparisons can be odious, so can assumptions.
Topics: Acetates; Amines; Anticonvulsants; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Quality of Life; Treatment Outcome; Triazines; Vigabatrin | 1996 |
Hemodialysis and hemoperfusion for treatment of valproic acid and gabapentin poisoning.
Topics: Acetates; Adult; Amines; Anticonvulsants; Biomarkers; Blood Chemical Analysis; Chromatography, Thin Layer; Coma; Cyclohexanecarboxylic Acids; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Hemoperfusion; Humans; Hypotension; Intensive Care Units; Male; Renal Dialysis; Shock; Valproic Acid | 1996 |
Gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1996 |
Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain; Cyclohexanecarboxylic Acids; Diet; Disease Progression; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Mice, Transgenic; Oxidative Stress; Riluzole; Spinal Cord; Superoxide Dismutase; Survival Analysis; Thiazoles; Vitamin E | 1996 |
The anticonvulsant gabapentin decreases firing rates of substantia nigra pars reticulata neurons.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Rats; Rats, Wistar; Substantia Nigra | 1996 |
Gabapentin for behavioral agitation in Alzheimer's disease.
Topics: Acetates; Aged; Alzheimer Disease; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Haloperidol; Humans; Psychomotor Agitation; Treatment Outcome | 1997 |
Reflex sympathetic dystrophy treated with gabapentin.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain Measurement; Reflex Sympathetic Dystrophy | 1997 |
Treatment of acute mania with gabapentin.
Topics: Acetates; Acute Disease; Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Psychiatric Status Rating Scales | 1997 |
Colonic absorption of antiepileptic agents.
Topics: Acetates; Amines; Animals; Anticonvulsants; Biological Transport; Chromatography, High Pressure Liquid; Colon; Cyclohexanecarboxylic Acids; Dogs; Drug Overdose; Gabapentin; gamma-Aminobutyric Acid; Instillation, Drug; Intestinal Absorption; Intestine, Small; Phenytoin | 1997 |
Stuttering caused by gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Seizures; Stuttering | 1997 |
New treatment options for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines | 1997 |
New antiepileptic drugs: case studies.
Topics: Acetates; Amines; Anticonvulsants; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Resistance; Electroencephalography; Epilepsies, Partial; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Male; Topiramate; Triazines | 1997 |
Erythromelalgia pain managed with gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Child; Cyclohexanecarboxylic Acids; Erythromelalgia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain | 1997 |
Gabapentin, ineffective in normal rats, markedly reduces C-fibre evoked responses after inflammation.
Topics: Acetates; Afferent Pathways; Amines; Analgesics; Animals; Carrageenan; Cyclohexanecarboxylic Acids; Electric Stimulation; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Inflammation; Male; Nerve Fibers; Rats; Rats, Sprague-Dawley; Reference Values; Spinal Cord | 1997 |
Utility of the lethargic (lh/lh) mouse model of absence seizures in predicting the effects of lamotrigine, vigabatrin, tiagabine, gabapentin, and topiramate against human absence seizures.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Absence; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Mice; Nipecotic Acids; Tiagabine; Topiramate; Triazines; Vigabatrin | 1997 |
Spinal gabapentin is antinociceptive in the rat formalin test.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley | 1997 |
Spermine modulation of specific [3H]-gabapentin binding to the detergent-solubilized porcine cerebral cortex alpha 2 delta calcium channel subunit.
Topics: Acetates; Amines; Animals; Anticonvulsants; Calcium Channels; Cations, Divalent; Cerebral Cortex; Chromatography, Gel; Cyclohexanecarboxylic Acids; Detergents; Dialysis; Gabapentin; gamma-Aminobutyric Acid; Membrane Proteins; Polysorbates; Protein Binding; Radioligand Assay; Spermine; Swine; Tritium | 1997 |
Gabapentin in bipolar disorder.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Retrospective Studies | 1997 |
The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic pain.
Topics: Acetates; Acute Disease; Amines; Analgesics; Animals; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electroshock; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Lamotrigine; Male; Pain; Phenylcarbamates; Propylene Glycols; Rats; Rats, Sprague-Dawley; Triazines | 1997 |
Gabapentin for idiopathic trigeminal neuralgia: report of two cases.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Retreatment; Trigeminal Neuralgia | 1997 |
Incontinence during treatment with gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy; Fecal Incontinence; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Urinary Incontinence | 1997 |
A naturalistic study of the use of vigabatrin, lamotrigine and gabapentin in adults with learning disabilities.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Comorbidity; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Lamotrigine; Learning Disabilities; Male; Middle Aged; Retrospective Studies; Seizures; Social Behavior Disorders; Substance-Related Disorders; Treatment Outcome; Triazines; Vigabatrin | 1997 |
[Gabapentine--advances in the management of epilepsy].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1994 |
Psychomotor agitation following gabapentin use in brain injury.
Topics: Acetates; Adult; Akathisia, Drug-Induced; Amines; Analgesics; Brain Injuries; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Phantom Limb | 1997 |
[Gabapentin--a new anti-epileptic agent].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1994 |
Amelioration of refractory dysesthetic limb pain in multiple sclerosis by gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Multiple Sclerosis; Pain | 1997 |
Choreoathetosis as a side effect of gabapentin therapy in severely neurologically impaired patients.
Topics: Acetates; Adult; Amines; Anticonvulsants; Athetosis; Chorea; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Male | 1997 |
Neurochemical actions of gabapentin in mouse brain.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Mice, Inbred ICR | 1997 |
Effects of felbamate, gabapentin and lamotrigine on seizure parameters and excitability in the rat hippocampus.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Evoked Potentials; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Lamotrigine; Male; Phenylcarbamates; Propylene Glycols; Rats; Rats, Sprague-Dawley; Seizures; Triazines | 1997 |
Comparison of the preclinical anticonvulsant profiles of tiagabine, lamotrigine, gabapentin and vigabatrin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Lamotrigine; Male; Mice; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Tiagabine; Triazines; Vigabatrin | 1997 |
Changes in body weight with chronic, high-dose gabapentin therapy.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Body Weight; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Time Factors; Weight Gain; Weight Loss | 1997 |
Contrasting nutrient effects on the plasma levels of an amino acid-like antiepileptic agent from jejunal administration in dogs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Area Under Curve; Cyclohexanecarboxylic Acids; Diet; Dogs; Female; Food-Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Intestinal Absorption; Jejunum; Male; Rats; Rats, Sprague-Dawley | 1997 |
Gabapentin (neurontin) and S-(+)-3-isobutylgaba represent a novel class of selective antihyperalgesic agents.
Topics: Acetates; Amines; Analgesics; Animals; Calcium Channel Blockers; Calcium Channels; Cyclohexanecarboxylic Acids; Discrimination Learning; Drug Tolerance; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Motility; Hyperalgesia; Male; Morphine; Naloxone; Pregabalin; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1997 |
Gabapentin enhances the antinociceptive effects of spinal morphine in the rat tail-flick test.
Topics: Acetates; Amines; Analgesics; Animals; Bicuculline; Cyclohexanecarboxylic Acids; Drug Combinations; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Morphine; Movement; Naloxone; Narcotic Antagonists; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Tail | 1997 |
Gabapentin abuse in a cocaine user: implications for treatment?
Topics: Acetates; Adult; Amines; Anticonvulsants; Crack Cocaine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Self Medication; Stress Disorders, Post-Traumatic; Substance Withdrawal Syndrome; Substance-Related Disorders | 1997 |
Evaluation of gabapentin and S-(+)-3-isobutylgaba in a rat model of postoperative pain.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Morphine; Pain, Postoperative; Pregabalin; Rats; Rats, Sprague-Dawley | 1997 |
Alopecia associated with gabapentin: first case.
Topics: Acetates; Adolescent; Alopecia; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans | 1997 |
alpha2u-Globulin nephropathy and ravens: do ravens of a different feather flock together?
Topics: Acetates; Alpha-Globulins; Amines; Animals; Anticonvulsants; Carcinogenicity Tests; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney; Kidney Neoplasms; Rats; Reproducibility of Results | 1997 |
Acute treatment of bipolar depression with gabapentin.
Topics: Acetates; Acute Disease; Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 1997 |
Gabapentin for familial paroxysmal dystonic choreoathetosis.
Topics: Acetates; Amines; Antiparkinson Agents; Athetosis; Child, Preschool; Chorea; Cyclohexanecarboxylic Acids; Dystonia; Electroencephalography; Family Health; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Videotape Recording | 1997 |
Pain in Guillain-Barré syndrome.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Polyradiculoneuropathy | 1997 |
[Trials with gabapentin monotherapy in patients with complex partial or secondary generalized seizures].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electroencephalography; Epilepsies, Partial; Epilepsy, Complex Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Randomized Controlled Trials as Topic; Research Design; Treatment Outcome | 1997 |
Use of gabapentin in a case of facial neuritis.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Facial Neuralgia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Neuritis | 1997 |
Modulation of excitatory amino acids pathway: a possible therapeutic approach to chronic daily headache associated with analgesic drugs abuse.
Topics: Acetates; Adult; Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Lamotrigine; Male; Middle Aged; Migraine Disorders; Opioid-Related Disorders; Substance Withdrawal Syndrome; Triazines | 1997 |
The novel anticonvulsant, gabapentin, protects against both convulsant and anxiogenic aspects of the ethanol withdrawal syndrome.
Topics: Acetates; Amines; Animals; Anticonvulsants; Ataxia; Behavior, Animal; Cyclohexanecarboxylic Acids; Ethanol; Gabapentin; gamma-Aminobutyric Acid; Male; Maze Learning; Mice; Motor Activity; Seizures; Substance Withdrawal Syndrome | 1997 |
Gabapentin reverses the allodynia produced by the administration of anti-GD2 ganglioside, an immunotherapeutic drug.
Topics: Acetates; Amines; Analgesics; Animals; Antibodies, Monoclonal; Blood Pressure; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Gangliosides; Male; Pain; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine | 1998 |
[GabapentinE++--improved treatment possibility for epilepsy].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans | 1994 |
Characterization of the effects of gabapentin and 3-isobutyl-gamma-aminobutyric acid on substance P-induced thermal hyperalgesia.
Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Glutamate; Serine; Stereoisomerism; Substance P | 1998 |
Isolation of the [3H]gabapentin-binding protein/alpha 2 delta Ca2+ channel subunit from porcine brain: development of a radioligand binding assay for alpha 2 delta subunits using [3H]leucine.
Topics: Acetates; Amines; Animals; Calcium Channels; Cerebral Cortex; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Kinetics; Leucine; Macromolecular Substances; Neurons; Protein Binding; Radioligand Assay; Swine; Tritium | 1998 |
The effect of intrathecal gabapentin and 3-isobutyl gamma-aminobutyric acid on the hyperalgesia observed after thermal injury in the rat.
Topics: Acetates; Amines; Animals; Anticonvulsants; Burns; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Spinal; Male; Pain; Pregabalin; Rats; Rats, Sprague-Dawley; Reflex; Serine; Stereoisomerism; Structure-Activity Relationship | 1998 |
HIV neuropathy treated with gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; HIV Infections; Humans; Male; Middle Aged; Peripheral Nervous System Diseases | 1998 |
Overdose with gabapentin and lamotrigine.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Overdose; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines | 1997 |
Comparison of the effects of drugs on hyperexcitability induced in hippocampal slices by withdrawal from chronic ethanol consumption.
Topics: Acetates; Alcoholism; Amines; Animals; Behavior, Animal; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Diltiazem; Ethanol; Felodipine; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Isradipine; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Substance Withdrawal Syndrome | 1998 |
Sensitive high-performance liquid chromatographic method with fluorometric detection for the simultaneous determination of gabapentin and vigabatrin in serum and urine.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Sensitivity and Specificity; Spectrometry, Fluorescence; Vigabatrin | 1998 |
Gabapentin induced polyneuropathy.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Polyneuropathies | 1998 |
Isolated ataxia as an idiosyncratic side-effect under gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cerebellar Ataxia; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electroencephalography; Epilepsies, Partial; Epilepsy, Complex Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neurologic Examination | 1997 |
Rebound psychiatric and physical symptoms after gabapentin discontinuation.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Obsessive-Compulsive Disorder; Recurrence; Substance Withdrawal Syndrome | 1998 |
[Gabapentin--a new antiepileptic agent].
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Retrospective Studies | 1998 |
Gabapentin add-on therapy with adaptable dosages in 610 patients with partial epilepsy: an open, observational study. The French Gabapentin Collaborative Group.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome; Vigabatrin | 1998 |
Gabapentin for lancinating neuropathic pain.
Topics: Acetates; Acquired Immunodeficiency Syndrome; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neoplasms; Pain; Peripheral Nervous System Diseases; Reflex Sympathetic Dystrophy | 1998 |
Alternative uses of lamotrigine and gabapentin in the treatment of trigeminal neuralgia.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Triazines; Trigeminal Neuralgia | 1998 |
Effects of phenytoin, carbamazepine, and gabapentin on calcium channels in hippocampal granule cells from patients with temporal lobe epilepsy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Calcium Channels; Carbamazepine; Cyclohexanecarboxylic Acids; Dentate Gyrus; Epilepsy, Temporal Lobe; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Humans; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phenytoin; Pyramidal Cells | 1998 |
Anticonvulsant action of gabapentin during postnatal development in rats.
Topics: Acetates; Amines; Animals; Anticonvulsants; Behavior, Animal; Brain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Gabapentin; gamma-Aminobutyric Acid; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 1997 |
Failure of absorption of gabapentin after rectal administration.
Topics: Acetates; Administration, Oral; Administration, Rectal; Adolescent; Amines; Anticonvulsants; Biological Availability; Child; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Hospitalization; Humans; Intestinal Absorption; Intestinal Mucosa; Male; Rectum | 1997 |
Effects of systemic carbamazepine and gabapentin on spinal neuronal responses in spinal nerve ligated rats.
Topics: Acetates; Amines; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Cyclohexanecarboxylic Acids; Electric Stimulation; Electrophysiology; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligation; Male; Neurons; Rats; Rats, Sprague-Dawley; Spinal Nerves | 1998 |
New approaches to therapy of amyotrophic lateral sclerosis.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Animals; Brain-Derived Neurotrophic Factor; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Insulin-Like Growth Factor I; Mice; Riluzole | 1998 |
Gabapentin in geriatric psychiatry patients.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Dementia; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 1998 |
Activation of two types of brain glutamate dehydrogenase isoproteins by gabapentin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Cattle; Cyclohexanecarboxylic Acids; Enzyme Activation; Gabapentin; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Guanosine Triphosphate; Isoenzymes; Kinetics; Oxidation-Reduction | 1998 |
Identification of novel ligands for the gabapentin binding site on the alpha2delta subunit of a calcium channel and their evaluation as anticonvulsant agents.
Topics: Acetates; Amines; Animals; Anticonvulsants; Binding Sites; Calcium Channels; Cyclohexanecarboxylic Acids; Cyclohexanes; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Ligands; Male; Mice; Semicarbazides; Stereoisomerism; Structure-Activity Relationship | 1998 |
Increased seizure frequency associated with felbamate withdrawal in adults.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Phenylcarbamates; Propylene Glycols; Retrospective Studies; Seizures; Substance Withdrawal Syndrome; Treatment Outcome | 1998 |
Clinical experience using gabapentin adjunctively in patients with a history of mania or hypomania.
Topics: Acetates; Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome | 1998 |
Reduction of 3,4-diaminopyridine-induced biogenic amine synthesis and release in rat brain by gabapentin.
Topics: 4-Aminopyridine; 5-Hydroxytryptophan; Acetates; Amifampridine; Amines; Animals; Anticonvulsants; Biogenic Monoamines; Brain; Cyclohexanecarboxylic Acids; Dihydroxyphenylalanine; Dopamine; Gabapentin; gamma-Aminobutyric Acid; Male; Rats; Rats, Sprague-Dawley | 1998 |
[Prophylactic treatment with gabapentin in chronic daily headache resistant to other drugs].
Topics: Acetates; Adult; Aged; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Resistance; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Male; Middle Aged | 1998 |
Gabapentin in the treatment of adolescent mania: a case report.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Psychiatric Status Rating Scales | 1998 |
Gabapentin potentiation of the antiepileptic efficacy of vigabatrin in an in vitro model of epilepsy.
Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Animals; Anticonvulsants; Bicuculline; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Epilepsy; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium Deficiency; Polypharmacy; Seizures; Vigabatrin | 1998 |
Gabapentin as a potential treatment for anxiety disorders.
Topics: Acetates; Adult; Alprazolam; Amines; Anticonvulsants; Anxiety Disorders; Cyclohexanecarboxylic Acids; Diazepam; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Panic Disorder; Phobic Disorders | 1998 |
Gabapentin potentiates the antiseizure activity of certain anticonvulsants in DBA/2 mice.
Topics: Acetates; Acoustic Stimulation; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Synergism; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred DBA; Seizures | 1998 |
Negative modultors of excitatory amino acids in episodic and chronic migraine: preventing and reverting chronic migraine. Special lecture 7th INWIN Congress.
Topics: Acetates; Adult; Amines; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Humans; Ketamine; Male; Middle Aged; Migraine Disorders; Receptors, N-Methyl-D-Aspartate; Transaminases | 1998 |
Gabapentin inhibits calcium currents in isolated rat brain neurons.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Globus Pallidus; Male; Neocortex; Neostriatum; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar | 1998 |
Role of branched-chain aminotransferase isoenzymes and gabapentin in neurotransmitter metabolism.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Acetates; Amines; Animals; Animals, Newborn; Anticonvulsants; Astrocytes; Carbon Radioisotopes; Cells, Cultured; Cerebral Cortex; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Isoenzymes; Ketone Oxidoreductases; Mitochondria; Multienzyme Complexes; Neurons; Neurotransmitter Agents; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Transaminases | 1998 |
Advances in mood stabilizing medications.
Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium Carbonate; Thyrotropin-Releasing Hormone; Triazines | 1998 |
Attenuation of formalin-induced nociceptive behaviors following local peripheral injection of gabapentin.
Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Injections, Subcutaneous; Male; Nociceptors; Pain; Pain Measurement; Pregabalin; Rats; Rats, Sprague-Dawley; Serine | 1998 |
An open-label trial of gabapentin treatment of paroxysmal symptoms in multiple sclerosis patients.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Multiple Sclerosis; Pain Measurement; Spasm | 1998 |
Gabapentin relieves trigeminal neuralgia in multiple sclerosis patients.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclerosis; Trigeminal Neuralgia | 1998 |
A high-performance liquid chromatography micromethod for the simultaneous determination of vigabatrin and gabapentin in serum.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Microchemistry; Sensitivity and Specificity; Vigabatrin | 1998 |
Gabapentin treatment of mood disorders: a preliminary study.
Topics: Acetates; Adolescent; Adult; Aged; Ambulatory Care; Amines; Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Depressive Disorder; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Mood Disorders; Pilot Projects; Psychiatric Status Rating Scales; Retrospective Studies; Treatment Outcome | 1998 |
Cost-efficient use of gas chromatography-mass spectrometry: a "piggyback" method for analysis of gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans | 1998 |
[ETICS Study: Empirical therapy of idiopathic chronic singultus].
Topics: Acetates; Aged; Aged, 80 and over; Amines; Baclofen; Chronic Disease; Cisapride; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Agents; Hiccup; Humans; Male; Middle Aged; Omeprazole; Treatment Outcome | 1998 |
Gabapentin for disruptive behaviour in an elderly demented patient.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dementia; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; New York; Nursing Homes; Psychomotor Agitation | 1998 |
Effective treatment of orthostatic tremor with gabapentin.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Electromyography; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Isometric Contraction; Male; Middle Aged; Postural Balance; Posture; Tremor; Weight-Bearing | 1998 |
Renal impairment as a possible side effect of gabapentin. A single case report.
Topics: Acetates; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Diseases; Male | 1998 |
[Treatment of neuropathic pain with gabapentin ++].
Topics: Acetates; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia | 1998 |
The outcome of prescribing novel anticonvulsants in an outpatient setting: factors affecting response to medication.
Topics: Acetates; Adolescent; Adult; Ambulatory Care; Amines; Anticonvulsants; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Drug Prescriptions; Epilepsy; Female; Follow-Up Studies; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Patient Compliance; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Wales | 1998 |
Treatment of seizures in acute intermittent porphyria: safety and efficacy of gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Porphyria, Acute Intermittent; Treatment Outcome | 1998 |
Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats.
Topics: Acetates; Amines; Animals; Anticonvulsants; Biogenic Amines; Blood Platelets; Brain; Carbamazepine; Cyclohexanecarboxylic Acids; Dopamine; Dopamine Uptake Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium; Male; Norepinephrine; p-Chloroamphetamine; Phenytoin; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Syndrome; Synaptosomes; Tetrodotoxin; Triazines; Valproic Acid; Zonisamide | 1998 |
Systemic gabapentin and S(+)-3-isobutyl-gamma-aminobutyric acid block secondary hyperalgesia.
Topics: Acetates; Amines; Animals; Anticonvulsants; Burns; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Intraperitoneal; Male; Pain Threshold; Pregabalin; Rats; Rats, Sprague-Dawley | 1998 |
Stevens-Johnson syndrome associated with gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Stevens-Johnson Syndrome | 1998 |
A case of spinal cord injury-related pain with baseline rCBF brain SPECT imaging and beneficial response to gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Brain; Cerebrovascular Circulation; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain; Spinal Cord Injuries; Tomography, Emission-Computed, Single-Photon | 1998 |
The anti-allodynic effects of amitriptyline, gabapentin, and lidocaine in a rat model of neuropathic pain.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Infusions, Intravenous; Infusions, Parenteral; Lidocaine; Male; Neuralgia; Pain Threshold; Rats; Rats, Sprague-Dawley | 1998 |
Symptomatic treatment of painful neuropathy.
Topics: Acetates; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Pain | 1998 |
In vivo monitoring of gabapentin in rats: a microdialysis study coupled to capillary electrophoresis and laser-induced fluorescence detection.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Electrophoresis, Capillary; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gabapentin; gamma-Aminobutyric Acid; Hemofiltration; Male; Microdialysis; Rats; Rats, Wistar | 1998 |
Comments on Gould, PAIN, 74 (1998) 341-343.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocephalus, Normal Pressure; Male; Peripheral Nervous System Diseases | 1998 |
Gabapentin for treatment of neuropathic pain in a 12-year-old girl.
Topics: Acetates; Amines; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Nervous System Diseases; Pain; Postoperative Complications; Thoracotomy | 1998 |
A case of myokymia-cramp syndrome successfully treated with gabapentin.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Extremities; Fasciculation; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Muscle Cramp; Syndrome; Treatment Outcome | 1998 |
Pharmacological and neuroanatomical studies of the antinociceptive effects of intrathecally administered gabapentin.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Rats; Rats, Sprague-Dawley; Spinal Cord; Synaptic Transmission | 1998 |
Possible gabapentin-induced thyroiditis.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Thyroiditis | 1999 |
Gabapentin suppresses ectopic nerve discharges and reverses allodynia in neuropathic rats.
Topics: Acetates; Afferent Pathways; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electrophysiology; Exploratory Behavior; Gabapentin; gamma-Aminobutyric Acid; Male; Pain; Peripheral Nerve Injuries; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 1999 |
Skin eruption with gabapentin in a patient with repeated AED-induced Stevens-Johnson's syndrome.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Hypersensitivity; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Skin Diseases; Stevens-Johnson Syndrome | 1999 |
Gabapentin for painful diabetic neuropathy.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Randomized Controlled Trials as Topic; Reproducibility of Results | 1999 |
The reduction in paired-pulse inhibition in the rat hippocampus by gabapentin is independent of GABA(B) receptor receptor activation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Dentate Gyrus; Electric Stimulation; GABA Agonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Neural Inhibition; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 1999 |
Neuropathic pain after anti-HIV gene therapy successfully treated with gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Genetic Therapy; HIV Infections; Humans; Male; Pain Management; Peripheral Nervous System Diseases | 1999 |
An in vitro electrophysiological study on the effects of phenytoin, lamotrigine and gabapentin on striatal neurons.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Cerebral Cortex; Corpus Striatum; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Lamotrigine; Male; Membrane Potentials; Neurons; Phenytoin; Rats; Rats, Wistar; Triazines | 1999 |
Gabapentin prevents hyperalgesia during the formalin test in diabetic rats.
Topics: Acetates; Amines; Analgesics; Animals; Blood Glucose; Body Weight; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Female; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Pain Measurement; Rats; Rats, Sprague-Dawley | 1999 |
Gabapentin and pregabalin, but not morphine and amitriptyline, block both static and dynamic components of mechanical allodynia induced by streptozocin in the rat.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Animals; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperglycemia; Injections; Injections, Spinal; Male; Morphine; Pain; Physical Stimulation; Pregabalin; Rats; Rats, Sprague-Dawley; Skin; Streptozocin; Touch | 1999 |
Development of two stable oral suspensions for gabapentin.
Topics: Acetates; Administration, Oral; Amines; Anticonvulsants; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Compounding; Drug Stability; Drug Storage; Gabapentin; gamma-Aminobutyric Acid; Reproducibility of Results; Suspensions | 1999 |
Gabapentin as monotherapy in the treatment of acute mania.
Topics: Acetates; Acute Disease; Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 1999 |
Catatonia following gabapentin withdrawal.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Substance Withdrawal Syndrome | 1999 |
[Use of gabapentin in glossopharyngeal neuralgia].
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Glossopharyngeal Nerve; Humans; Male; Middle Aged; Neuralgia; Treatment Outcome | 1999 |
Gabapentin decreases the severity of dystonia at low doses in a genetic animal model of paroxysmal dystonic choreoathetosis.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cricetinae; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid | 1999 |
Transport of pregabalin in rat intestine and Caco-2 monolayers.
Topics: Acetates; Amines; Amino Acids; Animals; Anticonvulsants; Biological Transport; Caco-2 Cells; Colon; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ileum; In Vitro Techniques; Intestinal Mucosa; Male; Mannitol; Phenylalanine; Pregabalin; Rats; Rats, Sprague-Dawley | 1999 |
Gabapentin modifies extracellular opioid peptide content in amygdala: a microdialysis study.
Topics: Acetates; Amines; Amygdala; Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Extracellular Space; Gabapentin; gamma-Aminobutyric Acid; Male; Microdialysis; Opioid Peptides; Radioimmunoassay; Rats; Rats, Wistar; Synaptic Transmission | 1999 |
Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Lamotrigine; Male; Motor Activity; Pain Measurement; Phenols; Piperidines; Pyrrolidinones; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Triazines | 1999 |
The management of epilepsy in a hospital for people with a learning disability.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Utilization; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Hospitals, Psychiatric; Humans; Lamotrigine; Learning Disabilities; Male; Middle Aged; Phenobarbital; Triazines; United Kingdom; Vigabatrin | 1999 |
Successful treatment with gabapentin in the presence of hypersensitivity syndrome to phenytoin and carbamazepine: a report of three cases.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Hypersensitivity; Drug Interactions; Epilepsy, Complex Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1999 |
Gabapentin-induced ejaculatory failure and anorgasmia.
Topics: Acetates; Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Ejaculation; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Orgasm; Sexual Dysfunction, Physiological; Sexual Dysfunctions, Psychological | 1999 |
Mood stabilizer combinations for bipolar disorder.
Topics: Acetates; Adolescent; Age Factors; Amines; Antimanic Agents; Bipolar Disorder; Child; Cyclohexanecarboxylic Acids; Drug Eruptions; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Triazines; Valproic Acid | 1999 |
Rapid high-performance liquid chromatographic determination of serum gabapentin.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Child; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 1999 |
Automated microanalysis of gabapentin in human serum by high-performance liquid chromatography with fluorometric detection.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 1999 |
A patient with multiple sclerosis and Down's syndrome with a rare paroxysmal symptom at onset.
Topics: Acetates; Amines; Brain; Cyclohexanecarboxylic Acids; Down Syndrome; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Pelvic Pain; Triazines | 1999 |
Gabapentin for self-injurious behavior in Lesch-Nyhan syndrome.
Topics: Acetates; Amines; Child, Preschool; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Lesch-Nyhan Syndrome; Male; Self-Injurious Behavior; Treatment Outcome | 1999 |
Gabapentin attenuates nociceptive behaviors in an acute arthritis model in rats.
Topics: Acetates; Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Behavior, Animal; Carrageenan; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hot Temperature; Hyperalgesia; Injections, Spinal; Injections, Subcutaneous; Joints; Kaolin; Pain Measurement; Rats; Rats, Sprague-Dawley | 1999 |
Gabapentin as treatment for hemifacial spasm.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Hemifacial Spasm; Humans; Male; Middle Aged; Time Factors; Treatment Outcome | 1999 |
An in vitro investigation into conformational aspects of gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Calcium Channels; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Isomerism; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation; Temperature | 1999 |
Gabapentin for painful diabetic neuropathy.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain | 1999 |
Gabapentin for painful diabetic neuropathy.
Topics: Acetates; Amines; Analgesics; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain | 1999 |
Gabapentin for postherpetic neuralgia.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia | 1999 |
Behavioral effects of RS-45041-190, a selective I2 imidazoline ligand, in rats.
Topics: Acetates; Amines; Analgesics; Animals; Carrageenan; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Imidazoles; Imidazoline Receptors; Indoles; Injections, Intraperitoneal; Injections, Spinal; Isoindoles; Ligands; Male; Motor Activity; Pain; Rats; Rats, Sprague-Dawley; Receptors, Drug | 1999 |
The effect of intrathecal gabapentin on pain behavior and hemodynamics on the formalin test in the rat.
Topics: Acetates; Amines; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hemodynamics; Hindlimb; Injections, Spinal; Male; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley | 1999 |
Structural requirement of the calcium-channel subunit alpha2delta for gabapentin binding.
Topics: Acetates; Amines; Amino Acid Sequence; Animals; Anticonvulsants; Base Sequence; Binding Sites; Calcium Channels; COS Cells; Cyclohexanecarboxylic Acids; Disulfides; DNA Primers; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Point Mutation; Protein Structure, Quaternary; Recombinant Proteins; Sequence Deletion; Swine; Transfection | 1999 |
Use of gabapentin to treat taxane-induced myalgias.
Topics: Acetates; Amines; Analgesics; Antineoplastic Agents, Phytogenic; Cyclohexanecarboxylic Acids; Docetaxel; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Muscular Diseases; Paclitaxel; Pain; Taxoids | 1999 |
The race to control pain: more participants, more targets.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Nicotinic Agonists; Pain; Receptors, Drug; Sodium Channels | 1999 |
Gabapentin as a promising treatment for antipsychotic-induced movement disorders in schizoaffective and bipolar patients.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Antipsychotic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Dyskinesia, Drug-Induced; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychotic Disorders; Treatment Outcome | 1999 |
Gabapentin for the treatment of dysesthetic pain after reconstructive surgery.
Topics: Acetates; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Paresthesia; Plastic Surgery Procedures | 1999 |
Synthesis and biological evaluation of conformationally restricted Gabapentin analogues.
Topics: Acetates; Amines; Analgesics, Non-Narcotic; Animals; Convulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Molecular Structure; Rats | 1999 |
Neuropathic pain.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Antiviral Agents; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia | 1999 |
Lesson of the month: Systemic vasculitis or not? That is the question.
Topics: Acetates; Amines; Anticoagulants; Anticonvulsants; Brain; Carbamazepine; Central Nervous System Diseases; Clotrimazole; Cyclohexanecarboxylic Acids; Cyclophosphamide; Drug Hypersensitivity; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunosuppressive Agents; Liver; Magnetic Resonance Imaging; Male; Middle Aged; Vasculitis; Vasculitis, Leukocytoclastic, Cutaneous; Warfarin | 1999 |
Saturable transport of gabapentin at the blood-brain barrier.
Topics: Acetates; Amines; Animals; Anticonvulsants; Blood-Brain Barrier; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Plasma Exchange; Rats; Rats, Sprague-Dawley | 1999 |
Inhibition of uptake, steady-state currents, and transient charge movements generated by the neuronal GABA transporter by various anticonvulsant drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Binding Sites; Biological Transport; Carrier Proteins; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Conductivity; Female; GABA Plasma Membrane Transport Proteins; Gabapentin; gamma-Aminobutyric Acid; Kinetics; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Mice; Nipecotic Acids; Oocytes; Organic Anion Transporters; Patch-Clamp Techniques; Tiagabine; Valproic Acid; Vigabatrin; Xenopus laevis | 1999 |
Gabapentin for the management of agitation.
Topics: Acetates; Aggression; Amines; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychomotor Agitation | 1999 |
Using gabapentin to treat neuropathic pain.
Topics: Acetates; Adult; Amines; Analgesics; Anticonvulsants; Costs and Cost Analysis; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain, Postoperative; Time Factors | 1999 |
Gabapentin as an adjunctive treatment in bipolar disorder.
Topics: Acetates; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales | 1999 |
Evaluation of interaction between gabapentin and ibuprofen on the formalin test in rats.
Topics: Acetates; Amines; Analgesics; Analgesics, Non-Narcotic; Animals; Blood Pressure; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Ibuprofen; Injections, Intraperitoneal; Male; Pain Measurement; Rats; Rats, Sprague-Dawley | 1999 |
A case report of reduction in alcohol craving and protection against alcohol withdrawal by gabapentin.
Topics: Acetates; Adult; Alcohol Drinking; Alcoholism; Amines; Animals; Anticonvulsants; Comorbidity; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Ethanol; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mice; Obsessive-Compulsive Disorder; Substance Withdrawal Syndrome | 1999 |
An 8-year-old girl with unilateral facial and ear pain and isolated frontal headaches.
Topics: Acetates; Amines; Child; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Earache; Face; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Melkersson-Rosenthal Syndrome; Physician-Patient Relations; Professional Competence; Severity of Illness Index; Temporomandibular Joint Disorders; Tongue, Fissured | 1999 |
The long-term use of gabapentin, lamotrigine, and vigabatrin in patients with chronic epilepsy.
Topics: Acetates; Ambulatory Care; Amines; Anticonvulsants; Chronic Disease; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Longitudinal Studies; Medical Records; Multicenter Studies as Topic; Patient Dropouts; Pharmacoepidemiology; Proportional Hazards Models; Retrospective Studies; Survival Analysis; Treatment Outcome; Triazines; United Kingdom; Vigabatrin | 1999 |
Antinociceptive effect of gabapentin in the formalin test.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Nociceptors; Pain Measurement; Rats; Rats, Wistar | 1999 |
Anticonvulsant activity of PNU-151774E in the amygdala kindled model of complex partial seizures.
Topics: Acetates; Alanine; Amines; Amygdala; Animals; Anticonvulsants; Behavior, Animal; Benzylamines; Carbamazepine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Gabapentin; gamma-Aminobutyric Acid; Kindling, Neurologic; Lamotrigine; Male; Phenytoin; Rats; Rats, Wistar; Severity of Illness Index; Triazines | 1999 |
Antidepressant-induced bruxism successfully treated with gabapentin.
Topics: Acetates; Amines; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Bipolar Disorder; Bruxism; Cyclohexanecarboxylic Acids; Cyclohexanols; Depression; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Venlafaxine Hydrochloride | 1999 |
Neurontin: expanding the clinical experience. Proceedings of a symposium. Cannes, France, June 5, 1998.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans | 1999 |
Gabapentin therapy for vulvodynia.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pelvic Pain; Vulvar Diseases | 1999 |
On call. I am a 49-year-old man with diabetes. I take Glucophage and I'm careful with my diet. I also walk three miles almost every day. My blood sugar is always below 150, usually in the 130s. My problem is tingling in my fingers and pain in my feet, whi
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2000 |
Gabapentin-induced anorgasmia.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Orgasm; Pain, Postoperative; Thoracotomy | 1999 |
Gabapentin leads to remission of somatoform pain disorder with major depression.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Depressive Disorder; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Inguinal Canal; Middle Aged; Pain; Somatoform Disorders; Time Factors | 1999 |
A case of sustained massive gabapentin overdose without serious side effects.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cognition; Cyclohexanecarboxylic Acids; Drug Overdose; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Renal Insufficiency; Time Factors; Tremor; Valproic Acid | 1999 |
Open maintenance treatment of bipolar disorder spectrum patients who responded to gabapentin augmentation in the acute phase of treatment.
Topics: Acetates; Acute Disease; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Recurrence; Treatment Outcome | 1999 |
Cognitive effects of topiramate, gabapentin, and lamotrigine in healthy young adults.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cognition; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Topiramate; Triazines | 2000 |
Cognitive effects of topiramate, gabapentin, and lamotrigine in healthy young adults.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cognition; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Topiramate; Triazines | 2000 |
Intrathecally administered gabapentin inhibits formalin-evoked nociception and the expression of Fos-like immunoreactivity in the spinal cord of the rat.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Foot; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Immunohistochemistry; Injections, Spinal; Male; Neurons; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors | 2000 |
Gabapentin treatment for brachioradial pruritus.
Topics: Acetates; Administration, Oral; Amines; Arm; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Female; Forearm; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pruritus | 1999 |
Manic episode due to gabapentin treatment.
Topics: Acetates; Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans | 1999 |
Refractory epilepsy: treatment with new antiepileptic drugs.
Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Nipecotic Acids; Patient Dropouts; Retrospective Studies; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin | 2000 |
Gabapentin treatment in a child with delayed-onset hemichorea/hemiballismus.
Topics: Acetates; Adolescent; Age of Onset; Amines; Antiparkinson Agents; Basal Ganglia; Chorea; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dyskinesias; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Neural Pathways; Stroke; Treatment Outcome | 2000 |
Repeated administration of systemic gabapentin alleviates allodynia-like behaviors in spinally injured rats.
Topics: Acetates; Amines; Analgesics; Animals; Cold Temperature; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Pain; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Time Factors | 2000 |
Treatment of dementia-associated agitation with gabapentin.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dementia, Multi-Infarct; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mental Status Schedule; Neurologic Examination; Psychomotor Agitation | 2000 |
Gabapentin as add-on therapy in focal epilepsy: a computerized EEG study.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Brain; Brain Mapping; Cyclohexanecarboxylic Acids; Electroencephalography; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2000 |
Gabapentin-lactam, a close analogue of the anticonvulsant gabapentin, exerts convulsant activity in amygdala kindled rats.
Topics: Acetates; Amines; Amygdala; Animals; Anticonvulsants; Aza Compounds; Convulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Kindling, Neurologic; Rats; Rats, Wistar; Spiro Compounds | 2000 |
Inhibition of K(+)-evoked glutamate release from rat neocortical and hippocampal slices by gabapentin.
Topics: Acetates; Agatoxins; Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Neocortex; omega-Conotoxins; Potassium; Pregabalin; Rats; Rats, Sprague-Dawley; Spider Venoms | 2000 |
Gabapentin, an antiepileptic drug, improves memory storage in mice.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Male; Memory; Mice; Mice, Inbred Strains | 2000 |
Synergistic effect between intrathecal non-NMDA antagonist and gabapentin on allodynia induced by spinal nerve ligation in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Ligation; Male; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Spinal Nerves | 2000 |
Combination of donepezil and gabapentin for behavioral disorders in Alzheimer's disease.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Donepezil; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Male; Mental Disorders; Piperidines; Psychiatric Status Rating Scales; Treatment Outcome | 2000 |
Gabapentin prophylaxis of clozapine-induced seizures.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Antipsychotic Agents; Clozapine; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Schizophrenia; Secondary Prevention; Treatment Outcome | 2000 |
Improved sexual function in three men taking lamotrigine for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Erectile Dysfunction; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sexual Dysfunctions, Psychological; Triazines; Valproic Acid | 2000 |
Use of gabapentin in the treatment of childhood reflex sympathetic dystrophy.
Topics: Acetates; Amines; Child; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Leg; Recurrence; Reflex Sympathetic Dystrophy; Treatment Outcome | 2000 |
Antiallodynic effect of intrathecal gabapentin and its interaction with clonidine in a rat model of postoperative pain.
Topics: Acetates; Adrenergic alpha-Agonists; Amines; Amino Acids; Amino Acids, Cyclic; Analgesics; Animals; Behavior, Animal; Clonidine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Leucine; Male; Pain Threshold; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Reflex | 2000 |
Myoclonus associated with the use of gabapentin.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Myoclonus; Severity of Illness Index | 2000 |
Allosteric modulation of [(3)H]gabapentin binding by ruthenium red.
Topics: Acetates; Amines; Animals; Anticonvulsants; Binding Sites; Binding, Competitive; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Ligands; Magnesium Chloride; Membranes; Mice; Ruthenium Red; Spermine; Temperature | 2000 |
Gabapentin vs amitriptyline for the treatment of peripheral neuropathy.
Topics: Acetates; Amines; Amitriptyline; Analgesics, Non-Narcotic; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia | 2000 |
Gabapentin. CI 945, GOE 3450, Neurontin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Area Under Curve; Biological Availability; Child; Child, Preschool; Clinical Trials as Topic; Cross-Over Studies; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Leukemia, Myeloid, Acute; Migraine Disorders; Phobic Disorders | 1999 |
Dystonia in a patient treated with propranolol and gabapentin.
Topics: Acetates; Adrenergic beta-Antagonists; Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Drug Synergism; Dystonia; Essential Tremor; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Propranolol | 2000 |
Anticonvulsant efficacy of gabapentin and levetiracetam in phenytoin-resistant kindled rats.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Evaluation; Drug Resistance; Female; Gabapentin; gamma-Aminobutyric Acid; Kindling, Neurologic; Levetiracetam; Phenytoin; Piracetam; Rats; Rats, Wistar; Seizures | 2000 |
Complex regional pain syndrome (CRPS) with resistance to local anesthetic block: a case report.
Topics: Acetates; Amines; Amitriptyline; Analgesia, Epidural; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child; Cyclohexanecarboxylic Acids; Drug Resistance; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocodone; Lidocaine; Nerve Block; Physical Therapy Modalities; Posterior Horn Cells; Receptors, N-Methyl-D-Aspartate; Reflex Sympathetic Dystrophy; Sympathetic Nervous System | 2000 |
Gabapentin "add-on therapy" for idiopathic chronic hiccup (ICH).
Topics: Acetates; Aged; Amines; Baclofen; Chronic Disease; Cisapride; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Agents; Hiccup; Humans; Male; Middle Aged; Muscle Relaxants, Central; Omeprazole; Treatment Outcome | 2000 |
Gabapentin affects glutamatergic excitatory neurotransmission in the rat dorsal horn.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Neurons, Afferent; Neurotransmitter Agents; Nociceptors; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic; Synaptic Transmission | 2000 |
Changes in use of valproate and other mood stabilizers for patients with schizophrenia from 1994 to 1998.
Topics: Acetates; Adult; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Utilization; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium Carbonate; Male; Middle Aged; New York; Retrospective Studies; Schizophrenia; Schizophrenic Psychology; Valproic Acid | 2000 |
Gabapentin-induced mitogenic activity in rat pancreatic acinar cells.
Topics: Acetates; Amines; Animals; Binding, Competitive; Calcium; Cell Division; Cell Line; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation, Neoplastic; Genes, Immediate-Early; Mitogens; Organ Size; Pancreas; Rats; Rats, Wistar; Receptors, Cholecystokinin | 2000 |
Paroxysmal dystonia induced by exercise and acetazolamide.
Topics: Acetates; Acetazolamide; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dystonia; Exercise; Female; Gabapentin; gamma-Aminobutyric Acid; Humans | 2000 |
Gabapentin for treatment of thalamic pain syndrome.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain; Palliative Care; Thalamic Diseases | 2000 |
Anorgasmia in a patient with bipolar disorder type 1 treated with gabapentin.
Topics: Acetates; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Orgasm; Sexual Dysfunction, Physiological | 2000 |
Effects of gabapentin on brain GABA, homocarnosine, and pyrrolidinone in epilepsy patients.
Topics: Acetates; Adult; Amines; Anticonvulsants; Brain Chemistry; Carnosine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Occipital Lobe; Pyrrolidinones | 2000 |
Antinociceptive effect of gabapentin in rats.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Male; Pain Measurement; Rats; Rats, Wistar | 2000 |
Gabapentin's effects on hot flashes and hypothermia.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Hypothermia; Male; Middle Aged; Migraine Disorders | 2000 |
A microdialysis study on the mechanism of action of gabapentin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Nipecotic Acids; Potassium; Proline; Rats; Rats, Wistar; Substantia Nigra | 2000 |
Inhibition of neuronal Ca(2+) influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices.
Topics: 2-Amino-5-phosphonovalerate; Acetates; Amines; Animals; Aspartic Acid; Calcium; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Male; Neostriatum; Neurons; Neurotransmitter Agents; Norepinephrine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Potassium; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Synaptosomes; Tritium | 2000 |
The anticonvulsant compound gabapentin possesses anxiolytic but not amnesic effects in rats.
Topics: Acetates; Amines; Amnesia; Animals; Anti-Anxiety Agents; Anticonvulsants; Avoidance Learning; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Memory; Rats; Rats, Wistar | 2000 |
Gabapentin in seizures due to acute intermittent porphyria.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Porphyria, Acute Intermittent; Seizures | 2000 |
A comparison of four new antiepileptic medications.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Medical Records; Middle Aged; Retrospective Studies; Survival Analysis; Topiramate; Treatment Outcome; Triazines; Vigabatrin | 2000 |
Gabapentin in acute painful diabetic neuropathy.
Topics: Acetates; Acute Disease; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Palliative Care | 2000 |
Low-dose gabapentin combined with either lamotrigine or carbamazepine can be useful therapies for trigeminal neuralgia in multiple sclerosis.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Pain Measurement; Triazines; Trigeminal Neuralgia | 2000 |
A retrospective chart review of gabapentin for the treatment of aggressive and agitated behavior in patients with dementias.
Topics: Acetates; Aged; Aged, 80 and over; Aggression; Amines; Antimanic Agents; California; Cyclohexanecarboxylic Acids; Dementia; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Inpatients; Male; Medical Records; Middle Aged; Nursing Homes; Retrospective Studies; Social Behavior Disorders; Treatment Outcome | 2000 |
Gabapentin may be hazardous in myasthenia gravis.
Topics: Acetates; Action Potentials; Aged; Amines; Animals; Anticonvulsants; Autoantibodies; Cholinesterase Inhibitors; Contraindications; Cyclohexanecarboxylic Acids; Electric Stimulation; Electrophysiology; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Myasthenia Gravis; Pyridostigmine Bromide; Rats; Rats, Inbred Lew; Receptors, Cholinergic | 2000 |
Reversible acute renal allograft dysfunction due to gabapentin.
Topics: Acetates; Acute Disease; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney; Kidney Transplantation | 2000 |
Treating hot flashes with drugs.
Topics: Acetates; Adrenergic alpha-Antagonists; Amines; Anticonvulsants; Clonidine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hormone Replacement Therapy; Hot Flashes; Humans; Selective Serotonin Reuptake Inhibitors | 2000 |
Herpes zoster.
Topics: Acetates; Acute Disease; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia | 2000 |
Morphine and gabapentin decrease mechanical hyperalgesia and escape/avoidance behavior in a rat model of neuropathic pain.
Topics: Acetates; Amines; Analgesics; Animals; Avoidance Learning; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Morphine; Nerve Crush; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley | 2000 |
The effects of gabapentin in the rat hippocampus are mimicked by two structural analogs, but not by nimodipine.
Topics: Acetates; Amines; Animals; Anticonvulsants; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Cyclohexanes; Dentate Gyrus; Diazepam; Dose-Response Relationship, Drug; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Male; Neural Inhibition; Nimodipine; Pregabalin; Rats; Rats, Sprague-Dawley; Reaction Time; Seizures | 2000 |
Gabapentin for treatment of bipolar and schizoaffective disorders.
Topics: Acetates; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Psychotic Disorders | 1997 |
Gabapentin inhibits excitatory synaptic transmission in the hyperalgesic spinal cord.
Topics: Acetates; Amines; Animals; Antimanic Agents; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Excitatory Postsynaptic Potentials; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Membrane Potentials; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord; Streptozocin; Synaptic Transmission; Tetrodotoxin | 2000 |
Antinociception and (R,S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid antagonism by gabapentin in the rat spinal cord in vivo.
Topics: Acetates; Amines; Analgesics; Anesthesia; Animals; Bicuculline; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Iontophoresis; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2000 |
Gabapentin-induced modulation of interictal epileptiform activity related to different vigilance levels.
Topics: Acetates; Adult; Amines; Arousal; Cyclohexanecarboxylic Acids; Electroencephalography; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Sleep | 2000 |
Modulation of K(+)-induced synaptosomal calcium influx by gabapentin.
Topics: Acetates; Amines; Animals; Calcium; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Male; Osmolar Concentration; Potassium; Rats; Rats, Sprague-Dawley; Synaptosomes | 2000 |
Opsoclonus-myoclonus syndrome: gabapentin as a new therapeutic proposal.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Paraneoplastic Syndromes, Nervous System | 2000 |
Effect of riluzole and gabapentin on cocaine- and methamphetamine-induced behavioral sensitization in mice.
Topics: Acetates; Amines; Animals; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Cyclohexanecarboxylic Acids; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Methamphetamine; Mice; Motor Activity; Riluzole; Time Factors | 2000 |
Further evidence for the role of the alpha(2)delta subunit of voltage dependent calcium channels in models of neuropathic pain.
Topics: Acetates; Amines; Analgesics; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Male; Neuralgia; Rats; Rats, Sprague-Dawley; Streptozocin | 2000 |
Chronic cluster headache responding to gabapentin: a case report.
Topics: Acetates; Adult; Amines; Analgesics; Cluster Headache; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 2000 |
Pharmacological and immunohistochemical characterization of a mouse model of acute herpetic pain.
Topics: Acetates; Amines; Amitriptyline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Diclofenac; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Herpes Simplex; Herpesvirus 1, Human; Hyperalgesia; Mice; Mice, Inbred BALB C; Morphine; Neuralgia; Neurons, Afferent; Pain | 2000 |
Painful gynecomastia: an unusual toxicity of gabapentin?
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gynecomastia; Humans; Male; Middle Aged; Pain | 2000 |
Gabapentin for chronic pain in spinal cord injury: a case report.
Topics: Acetates; Adult; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Leg; Pain; Spinal Cord Injuries | 2000 |
Gabapentin, an adjuvant treatment for neuropathic pain in a cancer hospital.
Topics: Acetates; Amines; Analgesics; Cancer Care Facilities; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neoplasms; Pain | 2000 |
Gabapentin-induced mood changes with hypomanic features in adults.
Topics: Acetates; Adult; Affect; Amines; Anticonvulsants; Chlamydia Infections; Cyclohexanecarboxylic Acids; Encephalomyelitis; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Paresthesia; Social Behavior Disorders; Treatment Outcome | 2000 |
SUNCT syndrome responsive to gabapentin (Neurontin).
Topics: Acetates; Amines; Analgesics; Conjunctival Diseases; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Lacrimal Apparatus Diseases; Male; Middle Aged; Neuralgia; Nose Diseases; Retreatment; Sweating; Syndrome | 2000 |
[Treatment of chronic and neuropathic pain. Established amitriptyline and the new gabapentin].
Topics: Acetates; Amines; Amitriptyline; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Treatment Outcome | 2000 |
Effect of vigabatrin and gabapentin on phenytoin pharmacokinetics in the dog.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dogs; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Male; Phenytoin; Vigabatrin | 2000 |
Different effects of GABAergic anticonvulsants on 4-aminopyridine-induced spontaneous GABAergic hyperpolarizations of hippocampal pyramidal cells--implication for their potency in migraine therapy.
Topics: 4-Aminopyridine; Acetates; Amines; Analgesics; Animals; Anticonvulsants; Convulsants; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Humans; Membrane Potentials; Migraine Disorders; Nipecotic Acids; Pyramidal Cells; Tiagabine; Time Factors; Valproic Acid; Vigabatrin | 2000 |
Fast isocratic high-performance liquid chromatographic assay method for the simultaneous determination of gabapentin and vigabatrin in human serum.
Topics: Acetates; Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Vigabatrin | 2000 |
Anticonvulsant action and long-term effects of gabapentin in the immature brain.
Topics: Acetates; Amines; Animals; Anticonvulsants; Behavior, Animal; Brain; Convulsants; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Flurothyl; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Kainic Acid; Male; Maze Learning; Memory; Rats; Rats, Sprague-Dawley; Seizures; Space Perception | 2001 |
Stimulus-dependent modulation of [(3)H]norepinephrine release from rat neocortical slices by gabapentin and pregabalin.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Male; Neocortex; Norepinephrine; Potassium; Pregabalin; Rats; Rats, Sprague-Dawley | 2000 |
[Clinical utilization of new anti-epileptic agents].
Topics: Acetates; Amines; Anemia, Aplastic; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Visual Fields | 2000 |
Gabapentin therapy for cocaine cravings.
Topics: Acetates; Adult; Amines; Anticonvulsants; Behavior, Addictive; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Treatment Outcome | 2000 |
Antinociceptive effect of systemic gabapentin in mononeuropathic rats, depends on stimulus characteristics and level of test integration.
Topics: Acetates; Amines; Analgesics; Animals; Cold Temperature; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Male; Motor Activity; Nervous System Diseases; Nociceptors; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Vocalization, Animal | 2000 |
Long-term retention rates of lamotrigine, gabapentin, and topiramate in chronic epilepsy.
Topics: Acetates; Adolescent; Adult; Age of Onset; Aged; Amines; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Patient Compliance; Patient Dropouts; Proportional Hazards Models; Survival Analysis; Topiramate; Triazines | 2000 |
Valproate and other anticonvulsants for psychiatric disorders.
Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cognition Disorders; Cyclohexanecarboxylic Acids; Dizziness; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fructose; Gabapentin; gamma-Aminobutyric Acid; Heart Defects, Congenital; Humans; Lamotrigine; Nausea; Obesity; Stevens-Johnson Syndrome; Topiramate; Triazines; Valproic Acid | 2000 |
Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action.
Topics: Acetates; Amines; Amino Acid Sequence; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dimerization; Excitatory Postsynaptic Potentials; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Molecular Sequence Data; Neurons; Oocytes; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Sequence Homology, Amino Acid; Xenopus laevis | 2001 |
Malignant appearing cachexia in an older patient with Bruns-Garland syndrome.
Topics: Acetates; Aged; Amines; Analgesics; Cachexia; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diagnosis, Differential; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Muscular Atrophy; Pain; Syndrome | 2000 |
Gabapentin or amitriptyline for painful diabetic neuropathy?
Topics: Acetates; Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Family Practice; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Outcome | 2000 |
Gabapentin antinociception in mice with acute herpetic pain induced by herpes simplex virus infection.
Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Drug Tolerance; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Simplex; Herpesvirus 1, Human; Hyperalgesia; Mice; Mice, Inbred BALB C; Motor Activity; Naltrexone; Narcotic Antagonists; Pain | 2001 |
Rodent model of chronic central pain after spinal cord contusion injury and effects of gabapentin.
Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Chronic Disease; Contusions; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Male; Motor Activity; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reaction Time; Spinal Cord Injuries; Time Factors | 2000 |
Benzodiazepines and anticonvulsants for social phobia (social anxiety disorder).
Topics: Acetates; Alprazolam; Amines; Anticonvulsants; Benzodiazepines; Clinical Trials as Topic; Clonazepam; Cyclohexanecarboxylic Acids; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Phobic Disorders; Placebos; Pregabalin; Treatment Outcome; Valproic Acid | 2001 |
Evaluating the tolerability of the newer mood stabilizers.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Central Nervous System Diseases; Cyclohexanecarboxylic Acids; Drug Information Services; Fructose; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Humans; Incidence; Lamotrigine; Mental Disorders; Neurotoxicity Syndromes; Topiramate; Triazines; Valproic Acid | 2001 |
The effects of GABA(B) agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat.
Topics: Acetates; Amines; Analgesics; Animals; Baclofen; Cyclohexanecarboxylic Acids; Electric Stimulation; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; In Vitro Techniques; Inflammation; Neuralgia; Rats; Rats, Wistar; Spinal Nerve Roots | 2001 |
Effect of glibenclamide in gabapentin antinociception.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glyburide; Hypoglycemic Agents; Male; Morphine; Pain Measurement; Potassium Channels; Rats; Rats, Wistar | 2001 |
Gabapentin in phantom limb pain management in children and young adults: report of seven cases.
Topics: Acetates; Adult; Amines; Analgesics; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Palliative Care; Phantom Limb | 2001 |
Treatment of ciguatera poisoning with gabapentin.
Topics: Acetates; Adult; Amines; Animals; Anticonvulsants; Ciguatera Poisoning; Cyclohexanecarboxylic Acids; Female; Fishes, Poisonous; Gabapentin; gamma-Aminobutyric Acid; Humans; Poisoning | 2001 |
Gabapentin for misuse of homemade nicotine nasal spray.
Topics: Acetates; Administration, Intranasal; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Internet; Male; Middle Aged; Nebulizers and Vaporizers; Nicotine; Prescription Fees; Smoking Cessation; Tobacco Use Disorder | 2001 |
Gabapentin for the treatment of tinnitus: a case report.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Tinnitus | 2001 |
Function of leucine in excitatory neurotransmitter metabolism in the central nervous system.
Topics: Acetates; Amines; Animals; Astrocytes; Brain; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Isoenzymes; Ketoglutaric Acids; Leucine; Male; Mitochondria; Neurotransmitter Agents; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Transaminases | 2001 |
Adverse event monitoring in lamotrigine patients: a pharmacoepidemiologic study in the United Kingdom.
Topics: Acetates; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Death, Sudden; Drug Eruptions; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Lamotrigine; Male; Middle Aged; Neurotoxicity Syndromes; Pharmacoepidemiology; Product Surveillance, Postmarketing; Triazines; United Kingdom; Vigabatrin | 2001 |
Adjunctive gabapentin in treatment-resistant depression: a retrospective chart review.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Depressive Disorder; Dose-Response Relationship, Drug; Drug Resistance; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Recurrence; Retrospective Studies; Treatment Outcome | 2001 |
The effects of gabapentin on different ligand- and voltage-gated currents in isolated cortical neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetates; Amines; Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channels; Cerebral Cortex; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neurons; Potassium Channels; Pyramidal Cells; Rats; Rats, Wistar; Sodium Channels | 2001 |
Gabapentin-induced anorgasmia as a cause of noncompliance in a bipolar patient.
Topics: Acetates; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Male; Sexual Dysfunctions, Psychological | 2001 |
[Progressive encephalomyelitis with rigidity. Clinical and electrophysiological aspects].
Topics: Acetates; Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Electrophysiology; Encephalomyelitis; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Muscle Rigidity | 2001 |
Determination of the antiepileptics vigabatrin and gabapentin in dosage forms and biological fluids using Hantzsch reaction.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fluorescent Dyes; Gabapentin; gamma-Aminobutyric Acid; Humans; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tablets; Vigabatrin | 2001 |
Postherpetic pain control with concomitant illness?
Topics: Acetates; Aged; Aged, 80 and over; Amines; Analgesics; Analgesics, Opioid; Biological Availability; Comorbidity; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Heart Failure; Herpes Zoster Oticus; Humans; Kidney Failure, Chronic; Male; Meperidine; Metabolic Clearance Rate; Patient Selection | 2001 |
Gabapentin quantification in human plasma by high-performance liquid chromatography coupled to electrospray tandem mass spectrometry. Application to bioequivalence study.
Topics: Acetates; Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Spectrometry, Mass, Electrospray Ionization | 2001 |
ALS defeats gabapentin: reflections on another failed treatment.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Failure | 2001 |
Adjunctive gabapentin in patients with intellectual disability and bipolar spectrum disorders.
Topics: Acetates; Adult; Amines; Antimanic Agents; Bipolar Disorder; Comorbidity; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Male; Psychiatric Status Rating Scales; Psychotropic Drugs | 2001 |
Differences in gabapentin efficacy for cancer pain more apparent than real?
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neoplasms; Palliative Care | 2001 |
Gabapentin for treatment of behavioral and psychological symptoms of dementia.
Topics: Acetates; Aggression; Amines; Behavior; Cyclohexanecarboxylic Acids; Dementia, Vascular; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2001 |
Differential effect of gabapentin on neuronal and muscle calcium currents.
Topics: Acetates; Amines; Animals; Calcium Channels; Cells, Cultured; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Heart; Membrane Potentials; Mice; Muscle, Skeletal; Myocardium; Neurons; Reverse Transcriptase Polymerase Chain Reaction | 2001 |
Calcium channel alpha(2)delta subunits-structure and Gabapentin binding.
Topics: Acetates; Amines; Amino Acid Sequence; Animals; Binding Sites; Calcium Channels; COS Cells; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Protein Conformation; Sequence Homology, Amino Acid; Transfection | 2001 |
Gabapentin use in benzodiazepine dependence and detoxification.
Topics: Acetates; Alprazolam; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Substance-Related Disorders; Treatment Outcome | 2001 |
[The effect of gabapentin and gabapentin-lactam on retinal ganglion cell survival. Situation after acute retinal ischemia in animal models].
Topics: Acetates; Amines; Animals; Anticonvulsants; Aza Compounds; Cell Survival; Convulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Ischemia; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Retinal Diseases; Retinal Ganglion Cells; Retinal Vessels; Spiro Compounds; Time Factors | 2001 |
Using gabapentin to treat failed back surgery syndrome caused by epidural fibrosis: A report of 2 cases.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Diskectomy; Epidural Space; Female; Fibrosis; Gabapentin; gamma-Aminobutyric Acid; Humans; Laminectomy; Low Back Pain; Lumbar Vertebrae; Magnetic Resonance Imaging; Pain Measurement; Postoperative Complications; Recovery of Function | 2001 |
Recurrent hypoventilation and respiratory failure during gabapentin therapy.
Topics: Acetates; Aged; Amines; Analgesics; Anti-Anxiety Agents; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoventilation; Lung Diseases, Obstructive; Male; Peripheral Nervous System Diseases; Respiratory Insufficiency | 2001 |
Gabapentin and gabapentin monohydrate.
Topics: Acetates; Amines; Anticonvulsants; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen Bonding; Molecular Structure; Water | 2001 |
Gabapentin treatment of the non-refractory bipolar spectrum: an open case series.
Topics: Acetates; Adult; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Depressive Disorder; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome | 2001 |
Behavioral effects of agents active at the gamma-aminobutyric acid receptor complex in the staircase paradigm.
Topics: Acetates; Adjuvants, Immunologic; Amines; Animals; Anti-Anxiety Agents; Anxiety; Azabicyclo Compounds; Behavior, Animal; Brain; Clonazepam; Cyclohexanecarboxylic Acids; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Exploratory Behavior; Flumazenil; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Motor Activity; Neurons; Piperazines; Receptors, GABA-A | 2001 |
Modulation of K+-evoked [3H]-noradrenaline release from rat and human brain slices by gabapentin: involvement of KATP channels.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Glyburide; Hippocampus; Humans; Hypoglycemic Agents; In Vitro Techniques; Male; Neocortex; Norepinephrine; Pinacidil; Potassium Channels; Potassium Chloride; Rats; Rats, Wistar; Retrospective Studies; Vasodilator Agents | 2001 |
Gabapentin for behavioral dyscontrol with mental retardation.
Topics: Acetates; Adult; Amines; Anticonvulsants; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intellectual Disability; Mental Disorders; Psychomotor Agitation; Treatment Outcome | 2001 |
Three-month follow-up of shoulder-hand syndrome induced by phenobarbital and treated with gabapentin.
Topics: Acetaminophen; Acetates; Amines; Analgesics; Anticonvulsants; Arthralgia; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Metacarpophalangeal Joint; Middle Aged; Neuralgia; Pain; Phenobarbital; Reflex Sympathetic Dystrophy; Shoulder Pain; Treatment Outcome; Ulnar Nerve; Wrist Joint | 2001 |
Gabapentin for opiod-related myoclonus in cancer patients.
Topics: Acetates; Amines; Analgesics, Opioid; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Myoclonus; Neoplasms; Pain | 2001 |
Vincristine-induced allodynia in the rat.
Topics: Acetates; Amines; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Body Weight; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Ion Channel Gating; Male; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Vincristine | 2001 |
Gabapentin actions on N-methyl-D-aspartate receptor channels are protein kinase C-dependent.
Topics: Acetates; Amines; Animals; Cell Separation; Cyclohexanecarboxylic Acids; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glycine; Immunohistochemistry; Male; N-Methylaspartate; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate | 2001 |
The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain gamma-aminobutyric acid type B receptors negatively coupled to voltage-dependent calcium channels.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Baclofen; Calcium Channels; Calcium Signaling; Cyclohexanecarboxylic Acids; GABA Agonists; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; Mice; Mice, Transgenic; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2001 |
Effects of Gabapentin and Topiramate in primary rat astrocyte cultures.
Topics: Acetates; Amines; Animals; Anticonvulsants; Astrocytes; Cell Survival; Cells, Cultured; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; L-Lactate Dehydrogenase; Lipopolysaccharides; Nitric Oxide; Osmolar Concentration; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Topiramate | 2001 |
Oxcarbazepine in focal epilepsy and hepatic porphyria: a case report.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Comorbidity; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Enzyme Induction; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Germany; Humans; Liver; Male; Oxcarbazepine; Porphyria Cutanea Tarda; Porphyrias, Hepatic; Transaminases; Treatment Outcome | 2001 |
Effects of antiepileptic drugs on cognition.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; Triazoles; Vigabatrin | 2001 |
The putative OP(4) antagonist, [Nphe(1)]nociceptin(1-13)NH(2), prevents the effects of nociceptin in neuropathic rats.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Morphine; Narcotic Antagonists; Narcotics; Neuralgia; Nociceptin; Nociceptin Receptor; Opioid Peptides; Pain Threshold; Peptide Fragments; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Sciatic Nerve; Spinal Cord | 2001 |
Effect of gabapentin and lamotrigine on mechanical allodynia-like behaviour in a rat model of trigeminal neuropathic pain.
Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Lamotrigine; Ligation; Male; Nociceptors; Rats; Rats, Sprague-Dawley; Triazines; Trigeminal Neuralgia | 2001 |
Gabapentin inhibits the substance P-facilitated K(+)-evoked release of [(3)H]glutamate from rat caudial trigeminal nucleus slices.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neurokinin-1 Receptor Antagonists; Organ Culture Techniques; Piperidines; Potassium; Pregabalin; Rats; Rats, Inbred Strains; Stereoisomerism; Substance P; Trigeminal Nucleus, Spinal; Tritium | 2001 |
Charles Bonnet's syndrome: complete remission of complex visual hallucinations treated by gabapentin.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hallucinations; Humans; Syndrome; Visual Acuity | 2001 |
Anticonvulsant efficacy of gabapentin on kindling in the immature brain.
Topics: Acetates; Age Factors; Amines; Amygdala; Animals; Anticonvulsants; Behavior, Animal; Brain; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Female; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Kindling, Neurologic; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Seizures | 2001 |
Gabapentin as prophylaxis against steroid-induced mania.
Topics: Acetates; Amines; Anti-Inflammatory Agents; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Steroids | 2001 |
Gabapentin for the treatment of spasticity in patients with amyotrophic lateral sclerosis.
Topics: Acetates; Aged; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Motor Neuron Disease; Muscle Spasticity; Neurologic Examination; Treatment Outcome | 2001 |
Late-onset GM2 gangliosidosis presenting as burning dysesthesias.
Topics: Acetates; Adolescent; Amines; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Evoked Potentials, Somatosensory; Foot; Gabapentin; gamma-Aminobutyric Acid; Gangliosidoses, GM2; Humans; Male; Paresthesia; Sandhoff Disease; Treatment Outcome | 2001 |
Treatment of pain with gabapentin in a neonate.
Topics: Acetates; Amines; Analgesics; Arthrogryposis; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Male; Pain; Pain Measurement; Treatment Outcome | 2001 |
Gabapentin interference with urine histidine as measured by the Beckman amino acid analyser.
Topics: Acetates; Adolescent; Adult; Amines; Amino Acid Metabolism, Inborn Errors; Anticonvulsants; Cyclohexanecarboxylic Acids; False Positive Reactions; Female; Gabapentin; gamma-Aminobutyric Acid; Histidine; Humans; Male | 2001 |
[Pharmacotherapy for neuropathic pain caused by injury to the afferent nerve fibers].
Topics: Acetates; Amines; Analgesics, Non-Narcotic; Cyclohexanecarboxylic Acids; Drug Approval; Gabapentin; gamma-Aminobutyric Acid; Humans; Netherlands; Neuralgia; Neurons, Afferent; Pain, Intractable | 2001 |
Gabapentin in painful HIV-related neuropathy: a report of 19 patients, preliminary observations.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; HIV Infections; Humans; Male; Middle Aged; Nervous System Diseases; Pain; Pain Measurement; Palliative Care; Sleep | 2001 |
Gabapentin-associated aggression.
Topics: Acetates; Adult; Aggression; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2001 |
Gabapentin for pain control in cancer patients' wound dressing care.
Topics: Acetates; Amines; Analgesics; Bandages; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Mycosis Fungoides; Pain; Skin Neoplasms | 2001 |
Management strategies for refractory localization-related seizures.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Practice Patterns, Physicians'; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin | 2001 |
A pilot study of gabapentin as treatment for acquired nystagmus.
Topics: Acetates; Adult; Amines; Anticonvulsants; Brain Stem; Cerebrovascular Disorders; Cyclohexanecarboxylic Acids; Eye Movements; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Multiple Sclerosis; Nystagmus, Pathologic; Pilot Projects; Reflex, Vestibulo-Ocular; Vision Disorders; Visual Acuity | 1996 |
Assessing tinnitus and prospective tinnitus therapeutics using a psychophysical animal model.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Deafness; Diagnosis, Differential; Disease Models, Animal; Ear; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Male; Nipecotic Acids; Noise; Pitch Perception; Psychophysics; Rats; Rats, Long-Evans; Tiagabine; Tinnitus; Wounds and Injuries | 2001 |
Block by gabapentin of the facilitation of glutamate release from rat trigeminal nucleus following activation of protein kinase C or adenylyl cyclase.
Topics: Acetates; Adenylyl Cyclases; Amines; Analgesics; Animals; Colforsin; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Enzyme Activation; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Potassium; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Trigeminal Nuclei; Tritium | 2001 |
Gabapentin neurotoxicity in a chronic haemodialysis patient.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Epilepsy, Absence; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Nervous System; Renal Dialysis | 2001 |
Memory improving actions of gabapentin in mice: possible involvement of central muscarinic cholinergic mechanism.
Topics: Acetates; Acetylcholine; Amines; Animals; Avoidance Learning; Brain; Cholinergic Antagonists; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Memory; Mice; Neural Inhibition; Receptors, Muscarinic | 2001 |
Quetiapine-related tardive dyskinesia.
Topics: Acetates; Adult; Amines; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium; Quetiapine Fumarate; Topiramate | 2001 |
Mucosal uptake of gabapentin (neurontin) vs. pregabalin in the small intestine.
Topics: Acetates; Alkaline Phosphatase; Amines; Amino Acids; Animals; Anticonvulsants; Biological Transport, Active; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Microvilli; Pregabalin; Rabbits; Rats; Sodium; Temperature | 2001 |
[Constrictive arachnoiditis after pantopaque myelography causing syringomyelia and paraparesis: case report].
Topics: Acetates; Amines; Analgesics; Arachnoid Cysts; Arachnoiditis; Constriction, Pathologic; Contrast Media; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Iophendylate; Male; Middle Aged; Myelography; Paraparesis; Syringomyelia; Time Factors | 2001 |
Effect of gabapentin-like compounds on development and maintenance of morphine-induced conditioned place preference.
Topics: Acetates; Amines; Analgesics, Opioid; Animals; Conditioning, Operant; Cyclohexanecarboxylic Acids; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Microdialysis; Morphine; Nucleus Accumbens; Pregabalin; Rats | 2001 |
Gabapentin and methylphenidate treatment of a preadolescent with attention deficit hyperactivity disorder and bipolar disorder.
Topics: Acetates; Amines; Antimanic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Central Nervous System Stimulants; Child; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Methylphenidate | 2001 |
ALS defeats gabapentin: reflections on another failed treatment.
Topics: Acetates; Amines; Amyotrophic Lateral Sclerosis; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Failure | 2001 |
Spectrofluorimetric determination of vigabatrin and gabapentin in urine and dosage forms through derivatization with fluorescamine.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dosage Forms; Fluorescamine; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Molecular Structure; Reproducibility of Results; Spectrometry, Fluorescence; Vigabatrin | 2002 |
Changes in exploratory behavior as a measure of chronic central pain following spinal cord injury.
Topics: Acetates; Amines; Analgesics; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Exploratory Behavior; Gabapentin; gamma-Aminobutyric Acid; Habituation, Psychophysiologic; Male; Motor Activity; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2001 |
Tissue-specific expression and gabapentin-binding properties of calcium channel alpha2delta subunit subtypes.
Topics: Acetates; Amines; Amino Acids; Animals; Anticonvulsants; Binding Sites; Calcium Channels; Cell Line; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Protein Binding; Protein Isoforms; Protein Structure, Secondary; Protein Subunits; Radioligand Assay; Tissue Distribution | 2001 |
Treating painful diabetic neuropathy with gabapentin.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Costs; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Pain Measurement; Patient Selection; Treatment Outcome | 2001 |
Gabapentin for clozapine-related seizures.
Topics: Acetates; Aged; Amines; Antimanic Agents; Antipsychotic Agents; Clozapine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Schizophrenia, Paranoid; Seizures | 2001 |
Gabapentin use in geriatric patients with depression and bipolar illness.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Antidepressive Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Depressive Disorder; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 2001 |
Gabapentin therapy for genitofemoral and ilioinguinal neuralgia.
Topics: Acetates; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Femoral Neuropathy; Gabapentin; gamma-Aminobutyric Acid; Hernia, Inguinal; Humans; Male; Middle Aged; Nerve Compression Syndromes; Neuralgia; Pain, Postoperative | 2001 |
Antinociceptive effect of the novel compound OT-7100 in a diabetic neuropathy model.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hyperalgesia; Insulin; Male; Motor Neurons; Neural Conduction; Pain Threshold; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Time Factors | 2001 |
A 28-year-old man addicted to cocaine.
Topics: Acetates; Adult; Amines; Brain; Cocaine-Related Disorders; Cost of Illness; Crack Cocaine; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Risk Factors | 2001 |
AUStralian study of titration to effect profile of safety (AUS-STEPS): high-dose gabapentin (neurontin) in partial seizures.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Australia; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electroencephalography; Epilepsies, Partial; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Prospective Studies; Quality of Life; Treatment Outcome | 2001 |
Role of specific aminotransferases in de novo glutamate synthesis and redox shuttling in the retina.
Topics: Acetates; Alanine Transaminase; Amines; Amino Acids, Branched-Chain; Animals; Antimetabolites; Aspartate Aminotransferases; Cyclohexanecarboxylic Acids; Cycloserine; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Mitochondria; Neuroglia; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Retina; Subcellular Fractions; Transaminases | 2001 |
Metabolic approach of absence seizures in a genetic model of absence epilepsy, the GAERS: study of the leucine-glutamate cycle.
Topics: Acetates; Amines; Amino Acids, Branched-Chain; Animals; Brain; Carbon Monoxide; Cells, Cultured; Cerebral Cortex; Cyclohexanecarboxylic Acids; Disease Models, Animal; Energy Metabolism; Epilepsy, Absence; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Keto Acids; L-Lactate Dehydrogenase; Leucine; Male; Neurons; Rats; Rats, Mutant Strains; Synaptic Transmission; Synaptic Vesicles; Transaminases | 2001 |
Tremor associated with benign IgM paraproteinaemic neuropathy successfully treated with gabapentin.
Topics: Acetates; Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hand; Humans; Immunoglobulin M; Paraproteinemias; Severity of Illness Index; Treatment Outcome; Tremor | 2001 |
Gabapentin is not a GABAB receptor agonist.
Topics: Acetates; Amines; Amino Acid Sequence; Animals; Anticonvulsants; Binding, Competitive; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Rats; Receptors, GABA-B | 2001 |
Gabapentin-related dyskinesia.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Cyclohexanecarboxylic Acids; Dyskinesia, Drug-Induced; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2001 |
Gabapentin-associated hepatotoxicity.
Topics: Acetates; Amines; Analgesics; Chemical and Drug Induced Liver Injury; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2001 |
Gabapentin as add-on therapy in refractory partial epilepsy: a double-blind, placebo-controlled, parallel-group study. 1993.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Double-Blind Method; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; History, 20th Century; Humans; Placebos | 2001 |
Gabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neurones.
Topics: Acetates; Amines; Animals; Anticonvulsants; Calcium; Calcium Channels; Cells, Cultured; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Membrane Potentials; Neurons, Afferent; Patch-Clamp Techniques; Rats; Rats, Wistar | 2002 |
[Diabetic neuropathies].
Topics: Acetates; Amines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Electrophysiology; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperglycemia; Immunoglobulins, Intravenous; Linoleic Acid; Pain; Prognosis | 2001 |
Gabapentin-induced worsening of neuropsychiatric symptoms in dementia with lewy bodies: case reports.
Topics: Acetates; Aged; Amines; Cyclohexanecarboxylic Acids; Dementia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lewy Bodies; Male; Mental Health; Nervous System | 2002 |
Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex.
Topics: Acetates; Adolescent; Adult; Amines; Anticonvulsants; Calcium; Calcium Channel Blockers; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunoblotting; Male; Middle Aged; Neocortex; Neurons; Norepinephrine; omega-Agatoxin IVA; Potassium; Pregabalin; Quinoxalines; Receptors, AMPA; Synaptosomes | 2002 |
Gabapentin treatment of multiple piloleiomyoma-related pain.
Topics: Acetates; Administration, Oral; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Leiomyomatosis; Middle Aged; Pain; Skin Neoplasms | 2002 |
[Gabapentin in the treatment of chronic intractable pain].
Topics: Acetates; Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Pain, Intractable; Placebos; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Time Factors; Triazines | 2002 |
Treatment of alcohol withdrawal with gabapentin.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Ethanol; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Mood Disorders; Substance Withdrawal Syndrome | 2002 |
Vulvodynia--new and more effective approaches to therapy.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Outcome; Vulvar Diseases | 2002 |
Hyperhidrosis in pediatric spinal cord injury: a case report and gabapentin therapy.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hematoma, Epidural, Cranial; Humans; Hyperhidrosis; Spinal Cord Injuries | 2002 |
A combination of gabapentin and morphine mediates enhanced inhibitory effects on dorsal horn neuronal responses in a rat model of neuropathy.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Electrophysiology; Gabapentin; gamma-Aminobutyric Acid; Ligation; Male; Morphine; Nerve Fibers; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Cord Diseases; Spinal Nerves | 2002 |
Pregnancy registries in epilepsy.
Topics: Abnormalities, Drug-Induced; Acetates; Amines; Anticonvulsants; Australia; Cross-Cultural Comparison; Cyclohexanecarboxylic Acids; Data Collection; Databases as Topic; Epilepsy; Europe; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; India; Infant, Newborn; International Cooperation; Lamotrigine; Pregnancy; Pregnancy Complications; Product Surveillance, Postmarketing; Registries; Severity of Illness Index; Triazines; United Kingdom; Vigabatrin | 2001 |
Gabapentin for hot flashes in prostate cancer.
Topics: Acetates; Aged; Amines; Androgen Antagonists; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hot Flashes; Humans; Male; Prostatic Neoplasms | 2002 |
Gabapentin-mediated inhibition of voltage-activated Ca2+ channel currents in cultured sensory neurones is dependent on culture conditions and channel subunit expression.
Topics: Acetates; Amines; Animals; Anticonvulsants; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Coculture Techniques; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ion Channel Gating; Membrane Potentials; Neural Inhibition; Neurons, Afferent; Patch-Clamp Techniques; Rats; Rats, Wistar | 2002 |
Gabapentin in migraine prophylaxis: is it effective and well tolerated?
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders | 2002 |
The interaction between gabapentin and amitriptyline in the rat formalin test after systemic administration.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley | 2002 |
[Gabapentin treatment of glossopharyngeal neuralgia with cardiac syncope].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glossopharyngeal Nerve Diseases; Humans; Male; Middle Aged; Syncope | 2002 |
[Adult GM2 gangliosidosis: improvement of ataxia with GABAergic drugs].
Topics: Acetates; Adult; Amines; Ataxia; beta-N-Acetylhexosaminidases; Cerebellum; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Gangliosidoses, GM2; Humans; Male; Myokymia; Nipecotic Acids; Tiagabine; Tomography, X-Ray Computed | 2002 |
The effect of intrathecal gabapentin on mechanical and thermal hyperalgesia in neuropathic rats induced by spinal nerve ligation.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Ligation; Male; Rats; Rats, Sprague-Dawley; Spinal Nerves; Time Factors | 2002 |
Case reports - reversal of sensory deficit associated with pain relief after treatment with gabapentin.
Topics: Acetates; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Somatosensory Disorders | 2002 |
Comment on Rice ASC, Maton S, the Postherpetic Neuralgia Study Group (UK), gabapentin in postherpetic neuralgia: a randomized, double blind, placebo-controlled study.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Randomized Controlled Trials as Topic | 2002 |
Comment on Rice ASC, Maton S, the Postherpetic Neuralgia Study Group (UK), gabapentin in postherpetic neuralgia: a randomized, double blind, placebo-controlled study.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Randomized Controlled Trials as Topic | 2002 |
[Toxocara canis meningoradiculitis].
Topics: Acetates; Adrenal Cortex Hormones; Aged; Amines; Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Antibodies, Helminth; Anticonvulsants; Cerebrospinal Fluid Proteins; Chest Pain; Cyclohexanecarboxylic Acids; Eosinophilia; Gabapentin; gamma-Aminobutyric Acid; Glucose; Humans; Hyperesthesia; Immunoglobulin E; Magnetic Resonance Imaging; Male; Meningitis; Radiculopathy; Steroids; Toxocara canis; Toxocariasis; Tramadol | 2002 |
Effects of analgesics on delayed postherpetic pain in mice.
Topics: Acetates; Acute Disease; Acyclovir; Amines; Analgesics; Analgesics, Opioid; Animals; Antiviral Agents; Behavior, Animal; Cyclohexanecarboxylic Acids; DNA, Viral; Female; Gabapentin; gamma-Aminobutyric Acid; Herpesviridae Infections; Herpesvirus 1, Human; Mexiletine; Mice; Mice, Inbred BALB C; Morphine; Pain; Pain Measurement; Physical Stimulation | 2002 |
Gabapentin potentiates N-methyl-D-aspartate receptor mediated currents in rat GABAergic dorsal horn neurons.
Topics: Acetates; Afferent Pathways; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Fluorescent Dyes; Gabapentin; gamma-Aminobutyric Acid; Immunohistochemistry; Inflammation; Ion Channels; Isoquinolines; Lysine; Membrane Potentials; Nociceptors; Pain; Patch-Clamp Techniques; Posterior Horn Cells; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2002 |
Effect of some antiepileptic drugs on brain histaminergic systems in the rat.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain Chemistry; Cyclohexanecarboxylic Acids; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Histamine; Methylhistamines; Phenytoin; Rats; Rats, Wistar | 2002 |
The anticonvulsant gabapentin (neurontin) does not act through gamma-aminobutyric acid-B receptors.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cells, Cultured; Cyclohexanecarboxylic Acids; Dogs; Esophagogastric Junction; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Animal; Oocytes; Rats; Receptors, GABA-B; Recombinant Proteins; Synaptic Membranes; Xenopus laevis | 2002 |
Doctor sues company over unethical marketing.
Topics: Acetates; Advertising; Amines; Anticonvulsants; Conflict of Interest; Cyclohexanecarboxylic Acids; Drug Industry; Ethics, Professional; Gabapentin; gamma-Aminobutyric Acid; Humans; United States | 2002 |
Treatment of spasticity.
Topics: Acetates; Amines; Aminopyridines; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Clonidine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Muscle Spasticity; Paralysis; Rhizotomy | 2002 |
Gabapentin for neuropathic pain following spinal cord injury.
Topics: Acetates; Acute Disease; Adolescent; Adult; Aged; Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Paraplegia; Quadriplegia; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity; Spinal Cord Injuries; Withholding Treatment | 2002 |
Gabapentin (neuronetin) in the treatment of SUNCT syndrome.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders; Humans; Middle Aged; Pain | 2002 |
Gabapentin in complicated school refusal.
Topics: Acetates; Adolescent; Amines; Comorbidity; Cyclohexanecarboxylic Acids; Cyclohexanols; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydroxyzine; Male; Mental Disorders; Phobic Disorders; Treatment Outcome; Venlafaxine Hydrochloride | 2002 |
Gabapentin: resistant neuropathic pain and malignancy.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Resistance; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Rhabdomyosarcoma | 2001 |
Experimental conditions for the continuous subcutaneous infusion of four central analgesics in rats.
Topics: Acetates; Amines; Analgesics; Anesthetics, Dissociative; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Chronic Disease; Convulsants; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Hypothermia; Imipramine; Infusion Pumps, Implantable; Ketamine; Male; Morphine; Pain; Pain Measurement; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Solubility; Tetrabenazine | 2002 |
Block of L-type Ca2+ current by beauvericin, a toxic cyclopeptide, in the NG108-15 neuronal cell line.
Topics: Acetates; Action Potentials; Amines; Animals; Anti-Bacterial Agents; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cyclohexanecarboxylic Acids; Depsipeptides; Electrophysiology; Gabapentin; gamma-Aminobutyric Acid; Glioma; Kinetics; Mice; Neuroblastoma; Neurons; omega-Conotoxin GVIA; Peptides; Potassium; Rats; Tumor Cells, Cultured | 2002 |
Facial pain following sinonasal surgery or facial trauma.
Topics: Acetates; Adult; Aged; Amines; Amitriptyline; Analgesics, Non-Narcotic; Carbamazepine; Cyclohexanecarboxylic Acids; Endoscopy; Facial Injuries; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Paranasal Sinuses; Retrospective Studies | 2002 |
Gabapentin and vigabatrin increase GABA in the human neocortical slice.
Topics: Acetates; Adolescent; Adult; Amines; Animals; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Male; Middle Aged; Neocortex; Rats; Rats, Sprague-Dawley; Vigabatrin | 2002 |
Gabapentin treatment of impulsive-aggressive behaviour.
Topics: Acetates; Adult; Aggression; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Impulsive Behavior; Male; Psychiatric Status Rating Scales | 2002 |
Gabapentin-induced anorgasmia in women.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Libido; Sexual Dysfunctions, Psychological | 2002 |
Gabapentin toxicity requiring intubation in a patient receiving long-term hemodialysis.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Overdose; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoxia; Intubation; Kidney Failure, Chronic; Middle Aged; Renal Dialysis | 2002 |
Recurrent complex partial status epilepticus associated with tiagabine rechallenge.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Humans; Lorazepam; Male; Meningoencephalitis; Nipecotic Acids; Status Epilepticus; Tiagabine; Treatment Outcome | 2002 |
Strictly unilateral headache reminiscent of hemicrania continua resistant to indomethacin but responsive to gabapentin.
Topics: Acetates; Adult; Amines; Anti-Inflammatory Agents, Non-Steroidal; Blepharoptosis; Cyclohexanecarboxylic Acids; Diagnostic Imaging; Drug Resistance; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Male; Migraine Disorders; Neurologic Examination; Vomiting | 2002 |
Preferential action of gabapentin and pregabalin at P/Q-type voltage-sensitive calcium channels: inhibition of K+-evoked [3H]-norepinephrine release from rat neocortical slices.
Topics: Acetates; Amines; Animals; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neocortex; Norepinephrine; Potassium; Pregabalin; Rats; Rats, Sprague-Dawley; Tritium | 2002 |
[Psychomotor slowness of a mentally retarded woman].
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Clobazam; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypothyroidism; Persons with Mental Disabilities; Psychomotor Disorders; Thyrotropin; Thyroxine | 2001 |
Neurotransmitter mechanisms in gabapentin antinociception.
Topics: Acetates; Amines; Analgesics; Analysis of Variance; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Injections, Subcutaneous; Male; Neurotransmitter Agents; Pain Measurement; Rats; Rats, Wistar; Receptors, Neurotransmitter | 2002 |
Gabapentin suppresses cutaneous hyperalgesia following heat-capsaicin sensitization.
Topics: Acetates; Adult; Amines; Analgesics; Capsaicin; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Humans; Hyperalgesia; Male | 2002 |
Changes in expression of voltage-dependent ion channel subunits in dorsal root ganglia of rats with radicular injury and pain.
Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Expression Regulation; Male; Pain; Pain Measurement; Protein Subunits; Radiculopathy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Channels | 2002 |
Gabapentin for coeliac plexus pain.
Topics: Acetates; Aged; Amines; Analgesics; Celiac Plexus; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasm Invasiveness; Nervous System Neoplasms; Pain; Pancreatic Neoplasms | 2002 |
Massive gabapentin and presumptive quetiapine overdose.
Topics: Acetates; Amines; Anti-Anxiety Agents; Antipsychotic Agents; Coma; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Drug Overdose; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypotension; Middle Aged; Quetiapine Fumarate; Respiration, Artificial; Respiratory Insufficiency; Suicide, Attempted | 2002 |
Gabapentin treatment of glossopharyngeal neuralgia: a follow-up of four years of a single case.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Glossopharyngeal Nerve; Glossopharyngeal Nerve Diseases; Humans; Middle Aged; Tramadol; Treatment Outcome | 2002 |
Gabapentin and pregabalin suppress tactile allodynia and potentiate spinal cord stimulation in a model of neuropathy.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electric Stimulation; Electrophysiology; Gabapentin; gamma-Aminobutyric Acid; Injections; Ischemia; Male; Mononeuropathies; Pain; Pain Management; Posterior Horn Cells; Pregabalin; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Touch | 2002 |
Gabapentin in the treatment of SUNCT syndrome.
Topics: Acetates; Amines; Analgesics; Conjunctiva; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders; Humans; Middle Aged; Neuralgia; Syndrome; Tears | 2002 |
SUNCT responsive to gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Conjunctiva; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Orbit; Pain; Syndrome; Tears | 2002 |
Gabapentin inhibits presynaptic Ca(2+) influx and synaptic transmission in rat hippocampus and neocortex.
Topics: Acetates; Amines; Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Electrophysiology; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Ion Channel Gating; Male; Neocortex; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Presynaptic; Synaptic Transmission; Synaptosomes | 2002 |
Central post-stroke pain syndrome: yet another use for gabapentin?
Topics: Acetates; Activities of Daily Living; Administration, Oral; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Stroke; Syndrome; Time Factors; Treatment Outcome | 2002 |
Dissociation of charge movement from calcium release and calcium current in skeletal myotubes by gabapentin.
Topics: Acetates; Amines; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cells, Cultured; Cyclohexanecarboxylic Acids; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Ion Transport; Membrane Potentials; Mice; Muscle, Skeletal; Nifedipine; Patch-Clamp Techniques; Protein Subunits | 2002 |
Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit.
Topics: Acetates; Alternative Splicing; Amines; Amino Acid Sequence; Base Sequence; Biological Transport; Blotting, Northern; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Chromosome Mapping; Chromosomes, Human, Pair 12; Cloning, Molecular; Cyclohexanecarboxylic Acids; Exons; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunohistochemistry; Molecular Sequence Data; Protein Subunits; Sequence Homology, Amino Acid; Tissue Distribution | 2002 |
[A relief from neural pain--gabapentin helped against hip ache in a girl with cerebral palsy].
Topics: Acetates; Adolescent; Amines; Analgesics; Arthralgia; Cerebral Palsy; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hip Joint; Humans; Muscle Spasticity; Treatment Outcome | 2001 |
Comparison of antiepileptic drugs tiagabine, lamotrigine, and gabapentin in mouse models of acute, prolonged, and chronic nociception.
Topics: Acetates; Acute Disease; Adrenergic alpha-Agonists; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Dynorphins; Formaldehyde; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Injections, Intraperitoneal; Injections, Spinal; Lamotrigine; Male; Mice; Mice, Inbred ICR; Nipecotic Acids; Pain; Pain Measurement; Reaction Time; Tiagabine; Triazines | 2002 |
The 'number needed to treat' with levetiracetam (LEV): comparison with the other new antiepileptic drugs (AEDs).
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2002 |
Re: Lasso-de-la-Vega et al. gabapentin as a probable cause of hepatotoxicity and eosinophilia.
Topics: Acetates; Amines; Analgesics; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Ciprofloxacin; Cyclohexanecarboxylic Acids; Eosinophilia; Gabapentin; gamma-Aminobutyric Acid; Humans; Liver Function Tests; Male; Middle Aged | 2002 |
Gabapentin and PTSD.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Stress Disorders, Post-Traumatic; Topiramate | 2002 |
Effect of gabapentin on the anticonvulsant activity of antiepileptic drugs against electroconvulsions in mice: an isobolographic analysis.
Topics: Acetates; Amines; Animals; Anticonvulsants; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Electroshock; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Kindling, Neurologic; Male; Memory; Mice; Motor Activity; Random Allocation; Seizures | 2002 |
A postmarketing surveillance study of gabapentin as add-on therapy for 3,100 patients in England.
Topics: Acetates; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; Amines; Anticonvulsants; Cause of Death; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Therapy, Combination; England; Epilepsy; Exanthema; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Male; Middle Aged; Product Surveillance, Postmarketing; Sleep Stages; Weight Gain | 2002 |
Is gabapentin a "Broad-spectrum" analgesic?
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Neuronal Plasticity; Pain | 2002 |
Gabapentin induced cholestasis.
Topics: Acetates; Amines; Anticonvulsants; Cholestasis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Humans; Liver Function Tests; Male; Middle Aged | 2002 |
Long-term regulation of voltage-gated Ca(2+) channels by gabapentin.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Oocytes; Protein Conformation; Rabbits; Rats; Recombinant Proteins; Seizures; Xenopus laevis | 2002 |
High-performance liquid chromatographic method for the determination of gabapentin in human plasma.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Therapeutic Equivalency | 2002 |
Down-regulation of N-type voltage-activated Ca2+ channels by gabapentin.
Topics: Acetates; Action Potentials; Amines; Amino Acid Transport System L; Animals; Anticonvulsants; Brain; Calcium; Calcium Channels, N-Type; Calcium Signaling; Cell Membrane; Cyclohexanecarboxylic Acids; Down-Regulation; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Neural Inhibition; Neurons; omega-Conotoxins; Rats; Tumor Cells, Cultured | 2002 |
Treating hot flashes with drugs: an update.
Topics: Acetates; Amines; Anticonvulsants; Antidepressive Agents, Second-Generation; Antihypertensive Agents; Clonidine; Cyclohexanecarboxylic Acids; Cyclohexanols; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Venlafaxine Hydrochloride | 2002 |
Gabapentin -- a promising treatment in glossodynia.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Glossalgia; Humans; Middle Aged; Psychophysiologic Disorders | 2002 |
Gabapentin and the neurokinin(1) receptor antagonist CI-1021 act synergistically in two rat models of neuropathic pain.
Topics: Acetates; Amines; Animals; Benzofurans; Carbamates; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Peripheral Nervous System Diseases; Piperidines; Rats; Rats, Sprague-Dawley | 2002 |
Anti-allodynic action of the tormentic acid, a triterpene isolated from plant, against neuropathic and inflammatory persistent pain in mice.
Topics: Acetates; Amines; Analgesics; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Inflammation; Ligation; Male; Mice; Motor Activity; Pain; Peripheral Nervous System Diseases; Phytotherapy; Plant Bark; Plant Extracts; Sciatic Nerve; Time Factors; Touch; Triterpenes | 2002 |
Gabapentin and pregabalin can interact synergistically with naproxen to produce antihyperalgesia.
Topics: Acetates; Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Calcium Channels; Cyclohexanecarboxylic Acids; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Naproxen; Pregabalin; Rats; Rats, Sprague-Dawley | 2002 |
Gabapentin for the treatment of familial erythromelalgia pain.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Erythromelalgia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged | 2002 |
Cavernous angioma in the brachium pontis presenting with trigeminal neuralgia: a case report.
Topics: Acetates; Amines; Analgesics; Central Nervous System Vascular Malformations; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hemangioma, Cavernous; Humans; Magnetic Resonance Imaging; Male; Mesencephalon; Middle Aged; Pain; Radiography; Trigeminal Neuralgia | 2002 |
[Edematous syndrome and alithiasic cholecystitis induced by gabapentin].
Topics: Acetates; Adult; Amines; Anticonvulsants; Cholecystitis; Cyclohexanecarboxylic Acids; Edema; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Syndrome | 2002 |
Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia.
Topics: Acetates; Adrenergic Uptake Inhibitors; Amines; Aminopyridines; Analgesia; Analgesics; Animals; Cells, Cultured; CHO Cells; Cricetinae; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Synergism; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Imipramine; Ketamine; Male; Morphine; Pain; Pain Measurement; Pain Threshold; Piperidines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Time Factors; Transfection | 2002 |
Combined pharmacologic and surgical approach to acquired nystagmus due to multiple sclerosis.
Topics: Acetates; Adult; Amines; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Diplopia; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Head Movements; Humans; Male; Multiple Sclerosis; Nystagmus, Pathologic; Oculomotor Muscles; Ophthalmologic Surgical Procedures; Posture; Visual Acuity | 2002 |
Gabapentin-induced bullous pemphigoid.
Topics: Acetates; Amines; Anticonvulsants; Azathioprine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pemphigoid, Bullous; Prednisolone; Treatment Outcome | 2002 |
Injury type-specific calcium channel alpha 2 delta-1 subunit up-regulation in rat neuropathic pain models correlates with antiallodynic effects of gabapentin.
Topics: Acetates; Amines; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Humans; Ligation; Male; Pain; Pain Measurement; Protein Subunits; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Spinal Cord; Up-Regulation | 2002 |
Determination of gabapentin in plasma by liquid chromatography with fluorescence detection after solid-phase extraction with a C18 column.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Spectrometry, Fluorescence | 2002 |
Effectiveness of adjunctive gabapentin in resistant bipolar disorder: is it due to anxious-alcohol abuse comorbidity?
Topics: Acetates; Adult; Aged; Alcoholism; Amines; Anticonvulsants; Antimanic Agents; Anxiety Disorders; Bipolar Disorder; Comorbidity; Cyclohexanecarboxylic Acids; Drug Resistance; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Sampling Studies; Treatment Outcome | 2002 |
Improvement of acquired pendular nystagmus by gabapentin: case report.
Topics: Acetates; Administration, Oral; Amines; Baclofen; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Multiple Sclerosis; Nystagmus, Pathologic; Treatment Outcome | 2001 |
Modulation of the in vivo effects of gabapentin by vigabatrin and SKF89976A.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dentate Gyrus; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Male; Neural Inhibition; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Reaction Time; Vigabatrin | 2002 |
Gabapentin in painful ophthalmoplegia.
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Tolosa-Hunt Syndrome | 2002 |
Gabapentin increases slow-wave sleep in normal adults.
Topics: Acetates; Adult; Amines; Anticonvulsants; Arousal; Cyclohexanecarboxylic Acids; Dizziness; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Polysomnography; Reaction Time; Sleep Stages; Sleep, REM; Wakefulness | 2002 |
Lumbar spinal cord stimulation for cervical-originated central pain: a case report.
Topics: Acetates; Amines; Antidepressive Agents, Tricyclic; Cervical Vertebrae; Cyclohexanecarboxylic Acids; Electric Stimulation Therapy; Electrodes, Implanted; Female; Foramen Magnum; Gabapentin; gamma-Aminobutyric Acid; Humans; Laminectomy; Lidocaine; Lumbosacral Region; Meningeal Neoplasms; Meningioma; Middle Aged; Pain; Pain Management; Pain, Intractable; Pain, Postoperative | 2002 |
Self-injurious behavior in children and adolescents with spinal cord injuries.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Occupational Therapy; Paresthesia; Self Mutilation; Spinal Cord Injuries | 2002 |
Nifedipine potentiates gabapentin antinociception in rats.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Male; Nifedipine; Pain Measurement; Rats; Rats, Wistar | 2002 |
Hyperhidrosis in social anxiety disorder.
Topics: Acetates; Adult; Amines; Calcium Channel Blockers; Clinical Trials as Topic; Clonazepam; Cognitive Behavioral Therapy; Cyclohexanecarboxylic Acids; Female; Fluoxetine; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperhidrosis; Male; Phobic Disorders; Prognosis; Retrospective Studies; Selective Serotonin Reuptake Inhibitors | 2002 |
Flumazenil and dialysis for gabapentin-induced coma.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Analgesics; Antidotes; Coma; Cyclohexanecarboxylic Acids; Flumazenil; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Phantom Limb; Renal Dialysis | 2003 |
Gabapentin-- actions on adult superficial dorsal horn neurons.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Excitatory Postsynaptic Potentials; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; N-Methylaspartate; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2002 |
Gabapentin withdrawal presenting as status epilepticus.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Male; Spine; Status Epilepticus; Substance Withdrawal Syndrome | 2002 |
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid | 2003 |
[Neuropathic pain. Often mishandled for years].
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Treatment Outcome | 2002 |
Coadministration of gabapentin or MK-801 with lamotrigine slows tolerance to its anticonvulsant effects on kindled seizures.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Drug Therapy, Combination; Drug Tolerance; Gabapentin; gamma-Aminobutyric Acid; Kindling, Neurologic; Lamotrigine; Male; Rats; Rats, Sprague-Dawley; Seizures; Triazines | 2003 |
Plasma gabapentin concentrations in children with epilepsy: influence of age, relationship with dosage, and preliminary observations on correlation with clinical response.
Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Analysis of Variance; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Statistics, Nonparametric | 2003 |
Gabapentin-induced paradoxical exacerbation of psychosis in a patient with schizophrenia.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Psychoses, Substance-Induced; Schizophrenia; Severity of Illness Index | 2002 |
Gabapentin increases the hyperpolarization-activated cation current Ih in rat CA1 pyramidal cells.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cations; Cyclic AMP; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Ion Channels; Male; Membrane Potentials; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Wistar | 2003 |
Colorimetric determination of gabapentin in pharmaceutical formulation.
Topics: Acetates; Amines; Anticonvulsants; Benzoquinones; Buffers; Capsules; Colorimetry; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Indicators and Reagents; Ninhydrin; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet | 2003 |
Gabapentin markedly reduces acetic acid-induced visceral nociception.
Topics: Acetates; Amines; Analgesics; Animals; Calcium; Cyclohexanecarboxylic Acids; Excitatory Amino Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Pain; Rats; Rats, Sprague-Dawley; Viscera | 2003 |
[Recognizing the "neck-tongue" syndrome].
Topics: Acetates; Amines; Analgesics; Analgesics, Non-Narcotic; Arthritis; Cervical Vertebrae; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypesthesia; Hypoglossal Nerve; Ibuprofen; Lingual Nerve; Middle Aged; Neck Pain; Pain; Spinal Diseases; Syndrome; Tongue; Tongue Diseases | 2003 |
Gabapentin therapy for amyotrophic lateral sclerosis: lack of improvement in neuronal integrity shown by MR spectroscopy.
Topics: Acetates; Aged; Amines; Amyotrophic Lateral Sclerosis; Aspartic Acid; Cell Survival; Creatine; Cyclohexanecarboxylic Acids; Energy Metabolism; Excitatory Amino Acid Antagonists; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Motor Cortex; Parietal Lobe; Reference Values; Treatment Outcome | 2003 |
The importance of the complete history in the discovery of a potential suicide: a case report.
Topics: Acetates; Amines; Analgesics, Opioid; Anti-Anxiety Agents; Anti-Bacterial Agents; Cyclohexanecarboxylic Acids; Depression; Diabetes Complications; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Leg Ulcer; Lower Extremity; Middle Aged; Morphine; Pain, Intractable; Peripheral Vascular Diseases; Sepsis; Suicide, Attempted | 2003 |
Anorgasmia and withdrawal syndrome in a woman taking gabapentin.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mood Disorders; Sexual Dysfunctions, Psychological; Substance Withdrawal Syndrome | 2003 |
Hot flashes. A closer look at causes and remedies.
Topics: Acetates; Amines; Antidepressive Agents; Body Temperature Regulation; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Hypothalamus; Norpregnenes | 2003 |
[Diagnose Sudeck's disease in good time and save your patient from martyrdom].
Topics: Acetates; Adrenergic Agents; Amines; Analgesics; Analgesics, Opioid; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Guanethidine; Humans; Physical Therapy Modalities; Reflex Sympathetic Dystrophy; Sympatholytics; Time Factors; World Health Organization | 2003 |
Suppression by gabapentin of pain-related mechano-responses in mice given orthotopic tumor inoculation.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Mechanoreceptors; Mechanotransduction, Cellular; Melanoma; Mice; Mice, Inbred C57BL; Pain; Pain Measurement; Physical Stimulation; Xenograft Model Antitumor Assays | 2003 |
Gabbing about gabapentin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Approval; Gabapentin; gamma-Aminobutyric Acid; Humans; Legislation, Drug; Neuralgia; United States; United States Food and Drug Administration | 2003 |
Spinal gabapentin and antinociception: mechanisms of action.
Topics: Acetates; Adrenergic alpha-Antagonists; Adrenergic Antagonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amines; Analgesics; Animals; Atropine; Cyclohexanecarboxylic Acids; Dihydroergocristine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Leucine; Male; Mecamylamine; Muscarinic Antagonists; N-Methylaspartate; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Pain Measurement; Quinazolines; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord; Thapsigargin; Triazoles | 2003 |
[Case report on a patient with SUNCT-syndrome].
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Middle Aged; Neuralgia; Pain; Syndrome; Treatment Outcome | 2003 |
Gabapentin and posttraumatic stress disorder.
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Cyclohexanecarboxylic Acids; Cyclohexanols; Depressive Disorder, Major; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Stress Disorders, Post-Traumatic; Venlafaxine Hydrochloride | 2003 |
Complete vasomotor collapse: an unusual manifestation of the carotid sinus reflex.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Morphine; Narcotic Antagonists; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley | 2003 |
Gabapentin blocks and reverses antinociceptive morphine tolerance in the rat paw-pressure and tail-flick tests.
Topics: Acetates; Amines; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Tolerance; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Morphine; Narcotic Antagonists; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Tail | 2003 |
Treatment of restless legs syndrome with gabapentin: a double-blind, cross-over study.
Topics: Acetates; Amines; Cross-Over Studies; Cyclohexanecarboxylic Acids; Dizziness; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Research Design; Restless Legs Syndrome; Sample Size | 2003 |
Comment on: Serpell et al., gabapentin in neuropathic pain syndromes: a randomised double-blind, placebo controlled trial (Pain 2002; 99: 557-66).
Topics: Acetates; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain Measurement; Randomized Controlled Trials as Topic; Research Design | 2003 |
A case of cutaneous leukocytoclastic vasculitis associated with gabapentin.
Topics: Acetates; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Foot; Gabapentin; gamma-Aminobutyric Acid; Humans; Vasculitis, Leukocytoclastic, Cutaneous | 2003 |
An East-West approach to the management of central post-stroke pain.
Topics: Acetates; Acupuncture; Aged; Amines; Amitriptyline; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Pain; Pain Management; Physical Therapy Modalities; Stroke; Tramadol; Triazines | 2003 |
Gabapentin for the treatment of ethanol withdrawal.
Topics: Acetates; Adult; Alcohol Withdrawal Seizures; Amines; Anticonvulsants; Benzodiazepines; Central Nervous System Depressants; Cyclohexanecarboxylic Acids; Ethanol; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Retrospective Studies; Substance Withdrawal Syndrome; Substance-Related Disorders | 2003 |
Simultaneous isocratic HPLC determination of vigabatrin and gabapentin in human plasma by dansyl derivatization.
Topics: Acetates; Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dansyl Compounds; Gabapentin; gamma-Aminobutyric Acid; Humans; Vigabatrin | 2003 |
Magnesium chloride and ruthenium red attenuate the antiallodynic effect of intrathecal gabapentin in a rat model of postoperative pain.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Spinal; Magnesium Chloride; Male; Morphine; Pain Measurement; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Ruthenium Red; Spermine | 2003 |
Gabapentin: the first preemptive anti-hyperalgesic for opioid withdrawal hyperalgesia?
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Mastectomy, Radical; Morphine; Pain, Postoperative; Substance Withdrawal Syndrome | 2003 |
ATP-sensitive potassium channels in rat primary afferent neurons: the effect of neuropathic injury and gabapentin.
Topics: Acetates; Amines; Animals; ATP-Binding Cassette Transporters; Basal Ganglia; Cyclohexanecarboxylic Acids; Diazoxide; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Glyburide; KATP Channels; Male; Neurons, Afferent; Neuroprotective Agents; Pain; Peripheral Nervous System Diseases; Pinacidil; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley | 2003 |
A comparison of Ca2+ channel blocking mode between gabapentin and verapamil: implication for protection against hypoxic injury in rat cerebrocortical slices.
Topics: Acetates; Amines; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cells, Cultured; Cerebral Cortex; Cyclohexanecarboxylic Acids; Fetus; Gabapentin; gamma-Aminobutyric Acid; Hypoxia, Brain; Nitric Oxide; omega-Agatoxin IVA; omega-Conotoxin GVIA; Potassium Chloride; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Verapamil | 2003 |
Gabapentin exposure in human pregnancy: results from the Gabapentin Pregnancy Registry.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Registries; Retrospective Studies; Surveys and Questionnaires | 2003 |
Gabapentin in geriatric mania.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Valproic Acid | 2003 |
Acute effects of gabapentin and pregabalin on rat forebrain cellular GABA, glutamate, and glutamine concentrations.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Injections, Intraperitoneal; Magnetic Resonance Spectroscopy; Male; Neurons; Pregabalin; Prosencephalon; Rats; Rats, Long-Evans; Vigabatrin | 2003 |
Doctor explains why he blew the whistle.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Drug Approval; Drug Industry; Drug Labeling; Fraud; Gabapentin; gamma-Aminobutyric Acid; Government Regulation; Humans; Marketing; Physicians; United States; United States Food and Drug Administration; Whistleblowing | 2003 |
Court papers suggest scale of drug's use: lawsuit says doctors were paid endorsers.
Topics: Acetates; Amines; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Approval; Drug Industry; Drug Labeling; Gabapentin; gamma-Aminobutyric Acid; Humans; Marketing; Physicians; Professional Misconduct; United States; Whistleblowing | 2003 |
Procedure for the monitoring of gabapentin with 2,4,6-trinitrobenzene sulfonic acid derivatization followed by HPLC with ultraviolet detection.
Topics: Acetates; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Reference Standards; Spectrophotometry, Ultraviolet; Trinitrobenzenesulfonic Acid | 2003 |
Gabapentin blocks L-type and P/Q-type Ca2+ channels involved in depolarization-stimulated nitric oxide synthase activity in primary cultures of neurons from mouse cerebral cortex.
Topics: Acetates; Amines; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Mice; Molecular Sequence Data; Neurons; Nifedipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; omega-Conotoxin GVIA; Potassium Chloride; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2003 |
Incomplete Brown-Séquard syndrome after methamphetamine injection into the neck.
Topics: Acetates; Adult; Amines; Brown-Sequard Syndrome; Causalgia; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Infarction; Injections; Lorazepam; Male; Methamphetamine; Morphine; Neck; Sclerosing Solutions; Spinal Cord; Spinal Cord Injuries; Spinal Cord Ischemia; Substance Abuse, Intravenous; Vasoconstrictor Agents | 2003 |
Vigabatrin, but not gabapentin or topiramate, produces concentration-related effects on enzymes and intermediates of the GABA shunt in rat brain and retina.
Topics: 4-Aminobutyrate Transaminase; Acetates; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Fructose; Gabapentin; gamma-Aminobutyric Acid; Male; Rats; Rats, Sprague-Dawley; Retina; Topiramate; Vigabatrin; Visual Fields | 2003 |
Different actions of gabapentin and baclofen in hippocampus from weaver mice.
Topics: Acetates; Amines; Animals; Baclofen; Cyclohexanecarboxylic Acids; Down-Regulation; Excitatory Amino Acid Antagonists; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Neural Inhibition; Organ Culture Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyramidal Cells; Receptors, GABA-B; Species Specificity; Synaptic Transmission | 2003 |
The truth is out there.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Drug Industry; Gabapentin; gamma-Aminobutyric Acid; Legislation, Drug; United States; United States Food and Drug Administration | 2003 |
Parke-Davis whistle-blower speaks at last.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Drug Industry; Gabapentin; gamma-Aminobutyric Acid; Humans; United States; United States Food and Drug Administration | 2003 |
The trend to move palliative care upstream.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Meningoencephalitis; Methadone; Pain; Pain Management; Palliative Care; Treatment Outcome; United States; West Nile Fever | 2003 |
Gabapentin reduces the mechanosensitivity of fine afferent nerve fibres in normal and inflamed rat knee joints.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Inflammation; Knee Joint; Male; Mechanotransduction, Cellular; Neurons, Afferent; Rats; Rats, Wistar | 2003 |
Treatment of post-herpetic pain in myasthenia gravis: exacerbation of weakness due to gabapentin.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Middle Aged; Myasthenia Gravis; Pain | 2003 |
Tiagabine synergistically interacts with gabapentin in the electroconvulsive threshold test in mice.
Topics: Acetates; Amines; Animals; Avoidance Learning; Behavior, Animal; Brain Chemistry; Cyclohexanecarboxylic Acids; Differential Threshold; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Excitatory Amino Acid Antagonists; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Memory; Mice; Motor Activity; Nipecotic Acids; Pain Threshold; Psychomotor Performance; Reaction Time; Tiagabine | 2003 |
Three drug reviews: one reformulated and one new antifungal agent and optimal dosing of the anticonvulsant gabapentin.
Topics: Acetates; Amines; Amphotericin B; Anticonvulsants; Antifungal Agents; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Pyrimidines; Triazoles; Voriconazole | 2003 |
Inflammation unmasks gabapentin's effect on A delta-fiber evoked excitatory postsynaptic currents in substantia gelatinosa neurons of rat spinal cord.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Nerve Fibers, Myelinated; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Substantia Gelatinosa; Synaptic Transmission; Tetrodotoxin | 2003 |
Helicobacter pylori hiccup.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Helicobacter Infections; Helicobacter pylori; Hiccup; Humans | 2003 |
Gabapentin reverses mechanical allodynia induced by sciatic nerve ischemia and formalin-induced nociception in mice.
Topics: Acetates; Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Erythrosine; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Lasers; Light; Male; Mice; Mice, Inbred Strains; Motor Activity; Pain Measurement; Photochemistry; Sciatic Nerve; Sciatic Neuropathy | 2003 |
[Effect of anticonvulsant gabapentin on visceral nociception and its relationship with amino acid neurotransmitters released from spinal cord].
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Male; Neurotransmitter Agents; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord; Viscera | 2003 |
Hemodynamic effects of gabapentin in rats.
Topics: Acetates; Amines; Analgesics; Animals; Blood Pressure; Catheterization; Cyclohexanecarboxylic Acids; Diastole; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Male; Rats; Rats, Sprague-Dawley; Systole; Time Factors | 2003 |
Gabapentin actions on Kir3 currents and N-type Ca2+ channels via GABAB receptors in hippocampal pyramidal cells.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Baclofen; Barium; Calcium Channel Blockers; Calcium Channels, N-Type; Cell Membrane; Cesium; Cyclohexanecarboxylic Acids; Epilepsy; Ethylmaleimide; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Gabapentin; gamma-Aminobutyric Acid; GTP-Binding Proteins; Hippocampus; Male; omega-Conotoxin GVIA; Organ Culture Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2003 |
Treatment of chronic neuropathic pain after traumatic central cervical cord lesion with gabapentin.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Arm; Carbamazepine; Central Cord Syndrome; Cervical Vertebrae; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Magnetic Resonance Imaging; Male; Middle Aged; Muscle Weakness; Pain, Intractable; Spinal Cord; Treatment Outcome | 2003 |
Reinforcing versus anticonvulsant drugs: effects on intracranial self-stimulation rate-frequency M50 indices.
Topics: Acetates; Amines; Amphetamine; Animals; Anticonvulsants; Central Nervous System Stimulants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Male; Medial Forebrain Bundle; Pentobarbital; Rats; Rats, Long-Evans; Reinforcement, Psychology; Self Stimulation | 2003 |
Potent analgesic effects of anticonvulsants on peripheral thermal nociception in rats.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Female; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Neurons, Afferent; Pain Measurement; Peripheral Nervous System Diseases; Phenytoin; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers | 2003 |
Acute effects of gabapentin on laboratory measures of aggressive and escape responses of adult parolees with and without a history of conduct disorder.
Topics: Acetates; Adult; Aggression; Amines; Conduct Disorder; Cyclohexanecarboxylic Acids; Escape Reaction; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Prisoners; Research Design | 2004 |
Pregabalin and gabapentin reduce release of substance P and CGRP from rat spinal tissues only after inflammation or activation of protein kinase C.
Topics: Acetates; Amines; Analgesics; Animals; Calcitonin Gene-Related Peptide; Cyclohexanecarboxylic Acids; Enzyme Activation; Foot; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Inflammation; Male; Phorbol 12,13-Dibutyrate; Pregabalin; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 2003 |
Comparative activity of the anti-convulsants oxcarbazepine, carbamazepine, lamotrigine and gabapentin in a model of neuropathic pain in the rat and guinea-pig.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hyperalgesia; Lamotrigine; Male; Neuralgia; Oxcarbazepine; Pain Threshold; Pressure; Rats; Rats, Wistar; Sciatic Nerve; Touch; Triazines; Wounds and Injuries | 2003 |
Great auricular neuralgia: a case report.
Topics: Acetates; Aged; Amines; Analgesics; Cervical Vertebrae; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Spinal Osteophytosis | 2003 |
Chronic pain syndrome after laparoscopic radical nephrectomy.
Topics: Acetates; Aged; Amines; Analgesics; Analgesics, Opioid; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Fentanyl; Flank Pain; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Neoplasms; Laparoscopy; Male; Middle Aged; Neoplasm Staging; Nephrectomy; Pain, Postoperative; Syndrome | 2003 |
Alpha-gamma hybrid peptides that contain the conformationally constrained gabapentin residue: characterization of mimetics of chain reversals.
Topics: Acetates; Amines; Biomimetic Materials; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Dipeptides; Gabapentin; gamma-Aminobutyric Acid; Hydrogen Bonding; Models, Molecular; Molecular Structure; Protein Structure, Secondary; Stereoisomerism | 2003 |
Anti-allodynic and anti-oedematogenic properties of the extract and lignans from Phyllanthus amarus in models of persistent inflammatory and neuropathic pain.
Topics: Acetates; Amines; Analgesics; Animals; Anti-Inflammatory Agents; Cyclohexanecarboxylic Acids; Edema; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Hexanes; Inflammation; Ligation; Lignans; Male; Mice; Motor Activity; Neutrophil Infiltration; Pain; Peripheral Nervous System Diseases; Peroxidase; Phyllanthus; Physical Stimulation; Plant Extracts; Psychomotor Performance; Sciatica; Solvents | 2003 |
[Unclear chronic aches. Often depression plays a part therein].
Topics: Acetates; Amines; Analgesics, Opioid; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Back Pain; Chronic Disease; Cyclohexanecarboxylic Acids; Depression; Diagnosis, Differential; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypochondriasis; Mianserin; Mirtazapine; Pain; Somatoform Disorders | 2003 |
Hiccup in patients with advanced cancer successfully treated with gabapentin: report of three cases.
Topics: Acetates; Adult; Amines; Anticonvulsants; Brain Neoplasms; Carcinoma, Small Cell; Colonic Neoplasms; Cyclohexanecarboxylic Acids; Fatal Outcome; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Pancreatic Neoplasms | 2003 |
[Gabapentin in the treatment of neuropathic pain in patients with type 2 diabetes mellitus].
Topics: Acetates; Aged; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Surveys and Questionnaires | 2003 |
Pharmacological characterisation of a rat model of incisional pain.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Celecoxib; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Evaluation, Preclinical; Etoricoxib; Foot; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Indomethacin; Male; Morphine; Muscle, Skeletal; Naproxen; Nociceptors; Pain Threshold; Pain, Postoperative; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sulfonamides; Sulfones; Time Factors; Weight-Bearing | 2004 |
The pattern of gabapentin use in a tertiary palliative care unit.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasms; Pain; Palliative Care; Retrospective Studies | 2003 |
[Clinical and neurochemical aspects of diaphragmatic myoclonus].
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diaphragm; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Myoclonus; Nipecotic Acids; Tiagabine | 2003 |
Postoperative pain and analgesic responses are similar in male and female Sprague-Dawley rats.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Cholinesterase Inhibitors; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Foot; Gabapentin; gamma-Aminobutyric Acid; Male; Morphine; Neostigmine; Pain Measurement; Pain Threshold; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Sex Factors | 2003 |
Limited efficacy of gabapentin in severe therapy-resistant epilepsies of learning-disabled patients.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Learning Disabilities; Long-Term Care; Residential Facilities; Retrospective Studies | 2003 |
Treatment of neuropathic orbital pain with gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Eye Diseases; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain | 2003 |
Gabapentin-induced hypoglycemia in a long-term peritoneal dialysis patient.
Topics: Acetates; Amines; C-Peptide; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Gluconeogenesis; Humans; Hypoglycemia; Hypotension; Insulin; Kidney Cortex; Kidney Failure, Chronic; Liver; Middle Aged; Pancreas; Parathyroidectomy; Peritoneal Dialysis; Postoperative Complications | 2003 |
[Efficacy and tolerability of gabapentin in the treatment of patients with neuropathic pain. Results of an observational study involving 5620 patients].
Topics: Acetates; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Pain Measurement; Patient Satisfaction; Time Factors | 2003 |
Genotype-dependence of gabapentin and pregabalin sensitivity: the pharmacogenetic mediation of analgesia is specific to the type of pain being inhibited.
Topics: Acetates; Amines; Analgesia; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Genotype; Male; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Pain; Pain Measurement; Pharmacogenetics; Pregabalin; Species Specificity | 2003 |
entla, a novel epileptic and ataxic Cacna2d2 mutant of the mouse.
Topics: Acetates; Alleles; Amines; Animals; Ataxia; Base Sequence; Blotting, Southern; Blotting, Western; Calcium; Calcium Channels; Cell Membrane; Chromosome Mapping; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Electrophysiology; Epilepsy; Exons; Female; Gabapentin; gamma-Aminobutyric Acid; Genetic Vectors; Genotype; Hippocampus; Homozygote; Immunohistochemistry; Ligands; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Models, Genetic; Molecular Sequence Data; Mutation; Phenotype; Protein Binding; Protein Structure, Tertiary; Time Factors | 2004 |
The use of clinical trial simulation to support dose selection: application to development of a new treatment for chronic neuropathic pain.
Topics: Acetates; Amines; Analgesics; Chronic Disease; Clinical Trials, Phase II as Topic; Computer Simulation; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Models, Chemical; Models, Statistical; Pain; Pain Measurement | 2003 |
A nitric oxide (NO)-releasing derivative of gabapentin, NCX 8001, alleviates neuropathic pain-like behavior after spinal cord and peripheral nerve injury.
Topics: Acetates; Amines; Animals; Aorta, Thoracic; Behavior, Animal; Cyclic GMP; Cyclohexanecarboxylic Acids; Cyclohexanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intraperitoneal; Lipopolysaccharides; Macrophages; Male; Mice; Muscle, Smooth; Nitrates; Nitric Oxide; Pain; Pain Measurement; PC12 Cells; Peripheral Nerve Injuries; Peripheral Nerves; Rabbits; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Spinal Cord Injuries; Tumor Necrosis Factor-alpha; Vasodilation | 2004 |
Determination of gabapentin in human plasma by capillary electrophoresis with laser-induced fluorescence detection and acetonitrile stacking technique.
Topics: Acetates; Acetonitriles; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Electrophoresis, Capillary; Gabapentin; gamma-Aminobutyric Acid; Humans; Lasers; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2004 |
Migraine-tic syndrome: a case report of a new headache type.
Topics: Acetates; Adult; Amines; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders; Humans; Migraine Disorders; Treatment Outcome; Trigeminal Neuralgia | 2004 |
Asterixis and toxic encephalopathy induced by gabapentin.
Topics: Acetates; Aged; Amines; Anticonvulsants; Brain; Brain Diseases; Carbamazepine; Cyclohexanecarboxylic Acids; Dyskinesia, Drug-Induced; Electromyography; Essential Tremor; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Motor Cortex; Oxcarbazepine | 2004 |
Change in opioid use after the initiation of gabapentin therapy in patients with postherpetic neuralgia.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Middle Aged; Neuralgia; Retrospective Studies | 2003 |
Myoclonic jerks associated with gabapentin.
Topics: Acetates; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Myoclonus; Pain | 2003 |
Synergistic interaction between spinal gabapentin and oral B vitamins in a neuropathic pain model.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Female; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Ligation; Pain; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Wistar; Spinal Nerves; Vitamin B Complex | 2003 |
Effect of K+ channel modulators on the antiallodynic effect of gabapentin.
Topics: Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar | 2004 |
Reduction by gabapentin of K+-evoked release of [3H]-glutamate from the caudal trigeminal nucleus of the streptozotocin-treated rat.
Topics: Acetates; Amines; Animals; Blood Glucose; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Pain; Pain Measurement; Physical Stimulation; Potassium; Rats; Trigeminal Nuclei | 2004 |
GABAA-benzodiazepine-chloride receptor-targeted therapy for tinnitus control: preliminary report.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Amines; Benzodiazepines; Chloride Channels; Clonazepam; Cyclohexanecarboxylic Acids; Female; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Humans; Instillation, Drug; Magnetic Resonance Imaging; Male; Middle Aged; Receptors, GABA; Receptors, GABA-A; Surveys and Questionnaires; Tinnitus; Tomography, Emission-Computed, Single-Photon | 2002 |
[Gabapentine-induced acute hepatitis].
Topics: Acetates; Acute Disease; Amines; Anticonvulsants; Chemical and Drug Induced Liver Injury; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2003 |
Potentially inappropriate antiepileptic drugs for elderly patients with epilepsy.
Topics: Acetates; Aged; Amines; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Phenytoin; Retrospective Studies; Triazines | 2004 |
Endogenous GABA does not mediate the inhibitory effects of gabapentin on spinal reflexes in rats.
Topics: Acetates; Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Neural Inhibition; Rats; Rats, Wistar; Reflex, Monosynaptic; Semicarbazides; Spinal Cord | 2004 |
Treatment with the antiepileptic drugs phenytoin and gabapentin ameliorates seizure and paralysis of Drosophila bang-sensitive mutants.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drosophila; Drosophila Proteins; Gabapentin; gamma-Aminobutyric Acid; Mutation; Paralysis; Phenytoin; Seizures | 2004 |
Isobolographic profile of interactions between tiagabine and gabapentin: a preclinical study.
Topics: Amines; Animals; Anticonvulsants; Convulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Seizures; Tiagabine | 2004 |
Gabapentin may inhibit synaptic transmission in the mouse spinal cord dorsal horn through a preferential block of P/Q-type Ca2+ channels.
Topics: Acetates; Amines; Animals; Calcium Channels, N-Type; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred BALB C; Neural Inhibition; Posterior Horn Cells; Spinal Cord; Synaptic Transmission | 2004 |
Chronic idiopathic singultus: is there life after cisapride?
Topics: Acetates; Amines; Anticonvulsants; Cisapride; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Agents; Hiccup; Humans; Indoles; Phosphodiesterase Inhibitors; Serotonin Receptor Agonists | 2004 |
The anti-hyperalgesic activity of retigabine is mediated by KCNQ potassium channel activation.
Topics: Acute Disease; Amines; Analgesics, Opioid; Animals; Carbamates; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Indoles; Ion Channel Gating; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Male; Mice; Peripheral Nervous System Diseases; Phenylenediamines; Physical Stimulation; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Pyridines; Rats; Rats, Wistar; Spinal Nerves; Touch; Tramadol | 2004 |
Interaction between anticonvulsants and human placental carnitine transporter.
Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techniques; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Models, Biological; Nipecotic Acids; Organic Cation Transport Proteins; Phenytoin; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Proteins; Solute Carrier Family 22 Member 5; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2004 |
Sample preparation and determination of gabapentin in venous and capillary blood using liquid chromatography-tandem mass spectrometry.
Topics: Acetates; Amines; Capillaries; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Mass Spectrometry; Pilot Projects; Veins | 2004 |
Autonomous stump movements responsive to gabapentin.
Topics: Acetates; Aged; Amines; Amputation Stumps; Cyclohexanecarboxylic Acids; Dyskinesias; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 2004 |
A study of gabapentin in the treatment of tonic-clonic seizures of alcohol withdrawal syndrome.
Topics: Acetates; Alcohol Withdrawal Seizures; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2004 |
Painful neuropathy alters the effect of gabapentin on sensory neuron excitability in rats.
Topics: Acetates; Action Potentials; Amines; Analgesics; Analysis of Variance; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electrophysiology; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Male; Microelectrodes; Nerve Fibers, Myelinated; Neurons, Afferent; Pain; Rats; Sciatic Nerve | 2004 |
Hot flashes refractory to HRT and SSRI therapy but responsive to gabapentin therapy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hormone Replacement Therapy; Hot Flashes; Humans; Selective Serotonin Reuptake Inhibitors; Treatment Failure | 2004 |
Effects of the suppression of acute herpetic pain by gabapentin and amitriptyline on the incidence of delayed postherpetic pain in mice.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Simplex; Herpesvirus 1, Human; Mice; Mice, Inbred BALB C; Pain; Physical Stimulation; Time Factors | 2004 |
N-Acridin-9-yl-butane-1,4-diamine derivatives: high-affinity ligands of the alpha2delta subunit of voltage gated calcium channels.
Topics: Acetates; Amines; Binding, Competitive; Calcium Channels; Cyclohexanecarboxylic Acids; Diamines; Gabapentin; gamma-Aminobutyric Acid; Ligands; Molecular Structure; Protein Binding; Protein Subunits; Structure-Activity Relationship | 2004 |
Vulvodynia.
Topics: Acetates; Amines; Anticonvulsants; Antidepressive Agents, Tricyclic; Biofeedback, Psychology; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Pain Management; Paresthesia; Vulvar Diseases | 2004 |
Can gabapentin be a safe alternative to hormonal therapy in the treatment of inappropriate sexual behavior in demented patients?
Topics: Acetates; Aged; Alzheimer Disease; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hormones; Humans; Male; Sexual Behavior; Sexual Dysfunctions, Psychological | 2003 |
Gabapentin (Neurontin) for chronic pain.
Topics: Acetates; Amines; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Costs; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain | 2004 |
Brachioradial pruritus: response to treatment with gabapentin.
Topics: Acetates; Aged; Amines; Arm; Cyclohexanecarboxylic Acids; Dermatologic Agents; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pruritus; Treatment Outcome | 2004 |
The use of gabapentin in a 12-year-old boy with cancer pain.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Child; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Morphine; Pain; Sarcoma, Ewing; Spinal Neoplasms; Treatment Outcome | 2004 |
Characteristic of interactions between intrathecal gabapentin and either clonidine or neostigmine in the formalin test.
Topics: Acetates; Adrenergic alpha-Agonists; Amines; Analgesics; Animals; Cholinesterase Inhibitors; Clonidine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Neostigmine; Pain Measurement; Rats; Rats, Sprague-Dawley | 2004 |
Identification and synthesis of [1,2,4]triazolo[3,4-a]phthalazine derivatives as high-affinity ligands to the alpha 2 delta-1 subunit of voltage gated calcium channel.
Topics: Amines; Analgesics; Binding Sites; Calcium Channel Blockers; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Inhibitory Concentration 50; Ligands; Phthalazines; Radioligand Assay; Structure-Activity Relationship | 2004 |
Effect of gabapentin derivates on mechanical allodynia-like behaviour in a rat model of chronic sciatic constriction injury.
Topics: Amines; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Cyclohexanols; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Memantine; Pain; Pain Threshold; Pregabalin; Prodrugs; Rats; Sciatic Neuropathy; Structure-Activity Relationship; Venlafaxine Hydrochloride | 2004 |
Determination of gabapentin-lactam in serum of patients under gabapentin therapy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Aza Compounds; Chromatography, Ion Exchange; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Spiro Compounds | 2004 |
Input resistance is voltage dependent due to activation of Ih channels in rat CA1 pyramidal cells.
Topics: 4-Aminopyridine; Acetates; Amines; Animals; Animals, Newborn; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Radiation; Electric Impedance; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Ion Channel Gating; Ion Channels; Membrane Potentials; Nickel; Patch-Clamp Techniques; Potassium Channel Blockers; Pyramidal Cells; Pyrimidines; Rats; Rats, Wistar; Tetrodotoxin | 2004 |
Use of gabapentin in the prevention of taxane-induced arthralgias and myalgias.
Topics: Acetates; Amines; Analgesics; Antineoplastic Agents, Phytogenic; Arthralgia; Cyclohexanecarboxylic Acids; Docetaxel; Gabapentin; gamma-Aminobutyric Acid; Humans; Muscle, Skeletal; Muscular Diseases; Paclitaxel; Retrospective Studies; Taxoids | 2004 |
Anticonvulsants as anxiolytics, part 2: Pregabalin and gabapentin as alpha(2)delta ligands at voltage-gated calcium channels.
Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Calcium Channels; Cyclohexanecarboxylic Acids; Fear; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Ligands; Pregabalin; Synaptic Transmission | 2004 |
Out with the old and in with the new...epilepsy drugs.
Topics: Acetates; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Drug Therapy; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Health Planning Guidelines; Humans | 2004 |
Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia.
Topics: Amines; Animals; Anticonvulsants; Brain Infarction; Brain Injuries; Brain Ischemia; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electroencephalography; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Male; Rats; Rats, Sprague-Dawley; Seizures | 2004 |
XP13512 [(+/-)-1-([(alpha-isobutanoyloxyethoxy)carbonyl] aminomethyl)-1-cyclohexane acetic acid], a novel gabapentin prodrug: I. Design, synthesis, enzymatic conversion to gabapentin, and transport by intestinal solute transporters.
Topics: Amines; Animals; Biological Transport; Caco-2 Cells; Carbamates; CHO Cells; Cricetinae; Cyclohexanecarboxylic Acids; Cytochrome P-450 Enzyme System; Dogs; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intestinal Mucosa; Large Neutral Amino Acid-Transporter 1; Membranes, Artificial; Monocarboxylic Acid Transporters; Prodrugs; Protein Binding; Rats; Symporters | 2004 |
XP13512 [(+/-)-1-([(alpha-isobutanoyloxyethoxy)carbonyl] aminomethyl)-1-cyclohexane acetic acid], a novel gabapentin prodrug: II. Improved oral bioavailability, dose proportionality, and colonic absorption compared with gabapentin in rats and monkeys.
Topics: Administration, Oral; Amines; Animals; Biological Availability; Carbamates; Colon; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Haplorhini; Injections, Intravenous; Intestinal Absorption; Prodrugs; Rats; Rats, Sprague-Dawley; Species Specificity; Tissue Distribution | 2004 |
Pfizer pleads guilty, but drug sales continue to soar.
Topics: Acetates; Amines; Cyclohexanecarboxylic Acids; Drug Industry; Drug Labeling; Gabapentin; gamma-Aminobutyric Acid; Humans; Marketing; United States | 2004 |
Anticonvulsants and the relief of chronic pain: pregabalin and gabapentin as alpha(2)delta ligands at voltage-gated calcium channels.
Topics: Acetates; Amines; Anticonvulsants; Calcium Channels; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Pain; Pain Measurement; Pregabalin; Somatoform Disorders; Synaptic Transmission | 2004 |
Dose-dependent severe arthralgia induced by gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Arthralgia; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Reflex Sympathetic Dystrophy | 2004 |
Conquering peripheral neuropathic pain.
Topics: Acetates; Amines; Analgesics; Anesthetics, Local; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Neuralgia | 2004 |
Superior oblique myokymia improved with gabapentin.
Topics: Acetates; Administration, Oral; Aged; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Trochlear Nerve Diseases | 2004 |
Effectiveness of gabapentin for treatment of burning mouth syndrome.
Topics: Acetates; Aged; Amines; Burning Mouth Syndrome; Cyclohexanecarboxylic Acids; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans | 2004 |
Warner-Lambert found guilty of promoting neurontin off label.
Topics: Acetates; Advertising; Amines; Cyclohexanecarboxylic Acids; Drug Industry; Gabapentin; gamma-Aminobutyric Acid; Humans; Product Labeling | 2004 |
Profiles in patient safety: when an error occurs.
Topics: Acetates; Aged; Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Administration Schedule; Emergency Medicine; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypotension; Hypoxia; Medication Errors; Pain; Phenytoin; Treatment Outcome | 2004 |
Gabapentin and behavioral disorders in severe Alzheimer disease.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 2004 |
Failed intrathecal analgesia following severe, terminal cancer pain.
Topics: Amines; Analgesics; Anesthetics, Local; Back Pain; Bupivacaine; Catheterization; Clonidine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Melanoma; Middle Aged; Morphine; Severity of Illness Index; Skin Neoplasms; Spinal Cord Neoplasms; Terminal Care; Tomography, X-Ray Computed; Treatment Failure | 2004 |
Gabapentin activates presynaptic GABAB heteroreceptors in rat cortical slices.
Topics: Amines; Animals; Baclofen; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Morpholines; Neocortex; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Presynaptic; Tritium | 2004 |
Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats.
Topics: Acute Disease; Amines; Amitriptyline; Animals; Conscious Sedation; Cyclohexanecarboxylic Acids; Cyclohexanols; Cyclopropanes; Disease Models, Animal; Drug Therapy, Combination; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Methyltyrosines; Milnacipran; Neuromuscular Junction; Norepinephrine; p-Chloroamphetamine; Pain; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Thiophenes; Venlafaxine Hydrochloride | 2004 |
Future Pain Drugs - Europe 2003. 15-16 September 2003, London, UK.
Topics: Acetaminophen; Acetates; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Delivery Systems; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Levetiracetam; Nitrates; Pain; Peripheral Nervous System Diseases; Piracetam; Pregabalin; Topiramate | 2003 |
Differential analgesic sensitivity of two distinct neuropathic pain models.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Animals; Cold Temperature; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dizocilpine Maleate; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Male; Morphine; Nerve Crush; Neuroprotective Agents; Pain; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy | 2004 |
Pharmacological characterisation of the rat brachial plexus avulsion model of neuropathic pain.
Topics: Acetates; Amines; Analgesics; Analysis of Variance; Animals; Brachial Plexus; Brachial Plexus Neuropathies; Celecoxib; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ketamine; Lidocaine; Male; Morphine; Neuralgia; Nociceptors; Pain Measurement; Pain Threshold; Pyrazoles; Radiculopathy; Rats; Rats, Wistar; Sulfonamides | 2004 |
Phantom breast pain as a source of functional loss.
Topics: Acetates; Activities of Daily Living; Amines; Anti-Anxiety Agents; Breast Neoplasms; Carcinoma in Situ; Comorbidity; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mastectomy, Modified Radical; Middle Aged; Multiple Sclerosis; Pain Measurement; Perceptual Disorders | 2004 |
A study comparing the actions of gabapentin and pregabalin on the electrophysiological properties of cultured DRG neurones from neonatal rats.
Topics: Amines; Animals; Animals, Newborn; Calcium; Calcium Channels; Cells, Cultured; Cyclohexanecarboxylic Acids; Electrophysiology; Fluorescent Dyes; Fura-2; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; GTP-Binding Proteins; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Pregabalin; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, GABA | 2004 |
Interaction between intrathecal gabapentin and adenosine in the formalin test of rats.
Topics: Adenosine; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Motor Activity; Pain Measurement; Rats; Rats, Sprague-Dawley | 2004 |
Whole-brain glutamate metabolism evaluated by steady-state kinetics using a double-isotope procedure: effects of gabapentin.
Topics: Acetates; Amines; Animals; Astrocytes; Bicarbonates; Brain; Brain Chemistry; Carbon Isotopes; Chromatography; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Male; Models, Neurological; Neurons; Rats; Rats, Sprague-Dawley; Regression Analysis; Retina; Time Factors | 2004 |
The biology and pharmacology of calcium channel alpha2-delta proteins Pfizer Satellite Symposium to the 2003 Society for Neuroscience Meeting. Sheraton New Orleans Hotel, New Orleans, LA November 10, 2003.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Binding Sites; Calcium Channels; Calcium Channels, L-Type; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Pregabalin; Rats; Societies, Scientific | 2004 |
Gabapentin-lactam, but not gabapentin, reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntington's disease.
Topics: Amines; Animals; Anticonvulsants; Aza Compounds; Corpus Striatum; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Huntington Disease; Injections, Subcutaneous; Male; Mice; Mice, Transgenic; Motor Activity; Neuroprotective Agents; Spiro Compounds; Survival Rate | 2004 |
Mechanism of action of alpha2delta ligands: voltage sensitive calcium channel (VSCC) modulators.
Topics: Acetates; Amines; Analgesics; Anti-Anxiety Agents; Anticonvulsants; Calcium Channel Blockers; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Models, Neurological; Pregabalin; Protein Structure, Quaternary; Sodium Channels; Structure-Activity Relationship | 2004 |
Treatment of bath PUVA-induced skin pain with gabapentin.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; PUVA Therapy; Treatment Outcome | 2004 |
Intrathecal gabapentin enhances the analgesic effects of subtherapeutic dose morphine in a rat experimental pancreatitis model.
Topics: Acetates; Acute Disease; Amines; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Bradykinin; Catheterization; Cholestasis; Cyclohexanecarboxylic Acids; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Morphine; Pain; Pain Measurement; Pancreatitis; Rats; Rats, Sprague-Dawley | 2004 |
Quantitation of poloxamers in pharmaceutical formulations using size exclusion chromatography and colorimetric methods.
Topics: Amines; Biphenyl Compounds; Chromatography, Gel; Colorimetry; Cyclohexanecarboxylic Acids; Ephedrine; Gabapentin; gamma-Aminobutyric Acid; Irbesartan; Molecular Structure; Poloxamer; Reproducibility of Results; Sensitivity and Specificity; Tablets; Tetrazoles | 2004 |
Restless legs syndrome: clinical experience with long-term treatment.
Topics: Adult; Aged; Amines; Clonazepam; Cyclohexanecarboxylic Acids; Dopamine Agonists; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Levodopa; Long-Term Care; Male; Middle Aged; Narcotics; Prospective Studies; Restless Legs Syndrome; Treatment Outcome | 2004 |
The effect of Vigabatrin, Lamotrigine and Gabapentin on the fertility, weights, sex hormones and biochemical profiles of male rats.
Topics: Amines; Analgesics; Animals; Antimanic Agents; Body Weight; Cyclohexanecarboxylic Acids; Female; Fertility; Follicle Stimulating Hormone; Gabapentin; gamma-Aminobutyric Acid; Lamotrigine; Male; Organ Size; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Testosterone; Triazines; Vigabatrin | 2004 |
Posttraining administration of pentylenetetrazol dissociates gabapentin effects on memory consolidation from that on memory retrieval process in mice.
Topics: Amines; Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Convulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Male; Memory; Mice; Mice, Inbred Strains; Naltrexone; Narcotic Antagonists; Pentylenetetrazole; Reaction Time; Retention, Psychology; Time Factors | 2004 |
Estradiol-induced changes in the activity of hippocampal neurons in network culture are suppressed by co-incubation with gabapentin.
Topics: 2-Amino-5-phosphonovalerate; Amines; Analysis of Variance; Animals; Calcium; Cyclohexanecarboxylic Acids; Diagnostic Imaging; Drug Interactions; Estradiol; Excitatory Amino Acid Antagonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Nerve Net; Neurons; Patch-Clamp Techniques; Picrotoxin; Potassium Chloride; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Reaction Time; Synaptic Transmission; Time Factors | 2004 |
Dual effects of gabapentin and pregabalin on glutamate release at rat entorhinal synapses in vitro.
Topics: Amines; Analysis of Variance; Animals; Anticonvulsants; Bicuculline; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Entorhinal Cortex; Excitatory Postsynaptic Potentials; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Isoleucine; Male; Neurons; omega-Conotoxin GVIA; Patch-Clamp Techniques; Pregabalin; Rats; Rats, Wistar; Spider Venoms; Statistics, Nonparametric; Tetrodotoxin | 2004 |
Gabapentin relieves mechanical, warm and cold allodynia in a rat model of peripheral neuropathy.
Topics: Amines; Animals; Cold Temperature; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Male; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley | 2004 |
Simultaneous high-performance liquid chromatographic analysis of pregabalin, gabapentin and vigabatrin in human serum by precolumn derivatization with o-phtaldialdehyde and fluorescence detection.
Topics: Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Gabapentin; gamma-Aminobutyric Acid; Humans; Indicators and Reagents; o-Phthalaldehyde; Pregabalin; Reference Standards; Reproducibility of Results; Solutions; Specimen Handling; Spectrometry, Fluorescence; Vigabatrin | 2004 |
[Anticonvulsant hypersensitivity syndrome].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Hypersensitivity; Ethosuximide; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lymphatic Diseases; Phenobarbital; Phenytoin; Syndrome; Triazines; Valproic Acid | 2004 |
The effects of intrathecal gabapentin on spinal morphine tolerance in the rat tail-flick and paw pressure tests.
Topics: Acetates; Amines; Analgesics; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Tolerance; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Morphine; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reaction Time | 2004 |
[Progressive encephalomyelitis with rigidity responsive to gabapentin: a pharmacological update].
Topics: Amines; Antiparkinson Agents; Clonidine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Encephalomyelitis; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunoglobulins, Intravenous; Muscle Rigidity; Nipecotic Acids; Tiagabine | 2004 |
Gas chromatography-tandem mass spectrometry analysis of gabapentin in serum.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Male; Mice; Sensitivity and Specificity | 2005 |
Essential tremor in the older adult: coping with primary symptoms.
Topics: Acetates; Adaptation, Psychological; Adrenergic beta-Antagonists; Aged; Alprazolam; Amines; Anticonvulsants; Antiparkinson Agents; Botulinum Toxins, Type A; Cyclohexanecarboxylic Acids; Essential Tremor; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuromuscular Agents; Primidone; Propranolol; Severity of Illness Index | 2004 |
Gabapentin-responsive idiopathic stabbing headache.
Topics: Adolescent; Adult; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans | 2004 |
Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents.
Topics: Adrenergic Uptake Inhibitors; Amines; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Ibuprofen; Inflammation; Male; Mice; Morphine; Norepinephrine; Pain; Pain Measurement; Postural Balance; Rats; Rats, Sprague-Dawley; Reaction Time; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2005 |
[Neuritis of the maxillary nerve. A 55-year-old housewife].
Topics: Amines; Analgesics; Anti-Inflammatory Agents; Cluster Headache; Cranial Nerve Diseases; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Facial Pain; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Maxillary Nerve; Middle Aged; Neuritis; Prednisone; Time Factors; Trigeminal Nerve; Trigeminal Neuralgia | 2004 |
Spastic paretic hemifacial contracture (SPHC) in a patient with multiple sclerosis. A clinical, EMG and neuroimaging study.
Topics: Adult; Amines; Baclofen; Blinking; Brain; Clonazepam; Cyclohexanecarboxylic Acids; Electromyography; Evoked Potentials; Excitatory Amino Acid Antagonists; Facial Muscles; Female; GABA Agonists; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Hemifacial Spasm; Humans; Magnetic Resonance Imaging; Multiple Sclerosis; Neurons; Pons | 2004 |
Gabapentin treatment for premature ejaculation.
Topics: Adult; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Ejaculation; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Sexual Dysfunction, Physiological | 2004 |
Western ALS Study Group.
Topics: Amines; Amyotrophic Lateral Sclerosis; Calcium Channel Blockers; Ciliary Neurotrophic Factor; Clinical Trials as Topic; Cooperative Behavior; Cyclohexanecarboxylic Acids; Cyclophosphamide; Gabapentin; gamma-Aminobutyric Acid; Humans; Minocycline; Societies, Medical; Treatment Outcome | 2004 |
[Use of gabapentin in group B -- DSM-IV personality disorders].
Topics: Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Diagnostic and Statistical Manual of Mental Disorders; Gabapentin; gamma-Aminobutyric Acid; Humans; Personality Disorders | 2004 |
Indirect photometric assay determination of gabapentin in bulk drug and capsules by capillary electrophoresis.
Topics: Amines; Capsules; Cyclohexanecarboxylic Acids; Electrophoresis, Capillary; Gabapentin; gamma-Aminobutyric Acid; Pharmaceutical Preparations; Photometry | 2004 |
[Evidence-based management of diabetic polyneuropathy. "Burning feet" alarm signal].
Topics: Amines; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Diabetic Foot; Diabetic Neuropathies; Disease Progression; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Glycated Hemoglobin; Humans; Pain Measurement; Paresthesia; Thioctic Acid | 2004 |
From the editor--drug companies under investigation.
Topics: Amines; Anticonvulsants; Antidepressive Agents, Second-Generation; Cyclohexanecarboxylic Acids; Drug Industry; Drug Information Services; Fraud; Gabapentin; gamma-Aminobutyric Acid; Humans; Nurse's Role; Paroxetine; Patient Advocacy; Psychiatric Nursing; Suicide; United States | 2004 |
Treatment of postherpetic neuralgia.
Topics: 2-Aminopurine; Acyclovir; Age Factors; Aged; Amines; Analgesics; Analgesics, Opioid; Antidepressive Agents, Tricyclic; Antiviral Agents; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Famciclovir; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Middle Aged; Neuralgia; Prodrugs; Risk Factors; Time Factors; Valacyclovir; Valine | 2004 |
Gabapentin for the treatment of itching produced by burns and wound healing in children: a pilot study.
Topics: Adolescent; Amines; Antipruritics; Burns; Child; Child Behavior Disorders; Child, Preschool; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Male; Pruritus; Wound Healing | 2004 |
Discriminative stimulus effects of the structurally novel cannabinoid CB1/CB2 receptor partial agonist BAY 59-3074 in the rat.
Topics: Alkanesulfonates; Amines; Amitriptyline; Animals; Baclofen; Behavior, Animal; Benzoxazines; Carbamazepine; Cyclohexanecarboxylic Acids; Cyclohexanols; Discrimination Learning; Dose-Response Relationship, Drug; Dronabinol; Gabapentin; gamma-Aminobutyric Acid; Indans; Male; Molecular Structure; Morphine; Morpholines; Naphthalenes; Nitriles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Sulfonic Acids | 2004 |
Interferon for hepatitis C patients with psychiatric disorders.
Topics: Amines; Antimanic Agents; Antiviral Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Risk Assessment; Treatment Outcome | 2004 |
Association between patient age and gabapentin serum concentration-to-dose ratio: a preliminary multivariate analysis.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Amines; Analysis of Variance; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multivariate Analysis; Retrospective Studies | 2004 |
[Gabapentin (Neurontin) and cancer pain: a pilot study].
Topics: Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasms; Pain; Pilot Projects; Prospective Studies | 2004 |
Oxcarbazepine (Trileptal) monotherapy dramatically improves quality of life in two patients with postherpetic neuralgia refractory to carbamazepine and gabapentin.
Topics: Aged; Amines; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Neuralgia; Oxcarbazepine; Quality of Life; Treatment Failure; Treatment Outcome | 2004 |
GABAB receptors do not mediate the inhibitory actions of gabapentin on the spinal reflex in rats.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microinjections; Neural Inhibition; Rats; Rats, Wistar; Receptors, GABA-B; Reflex; Spinal Cord | 2004 |
Monotherapy treatment of paruresis with gabapentin.
Topics: Amines; Anti-Anxiety Agents; Anxiety Disorders; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Patient Compliance; Treatment Outcome; Urination Disorders | 2005 |
Gabapentin normalizes spinal neuronal responses that correlate with behavior in a rat model of cancer-induced bone pain.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Bone Neoplasms; Cell Line, Tumor; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Male; Neoplasm Transplantation; Neurons; Osteotomy; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Spinal Cord; Temperature | 2005 |
Analysis of interactions between serotonin and gabapentin or adenosine in the spinal cord of rats.
Topics: Adenosine; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord | 2005 |
Neutropenia occurring after starting gabapentin for neuropathic pain.
Topics: Adenocarcinoma; Amines; Analgesics; Carcinoma, Non-Small-Cell Lung; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Pain; Peripheral Nervous System Diseases; Sepsis | 2004 |
Oral administration of B vitamins increases the antiallodynic effect of gabapentin in the rat.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Female; Gabapentin; gamma-Aminobutyric Acid; Ligation; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Wistar; Spinal Nerves; Vitamin B Complex | 2004 |
Synergistic interaction between gabapentin and metamizol in the rat formalin test.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Dipyrone; Dose-Response Relationship, Drug; Drug Synergism; Female; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Pain Measurement; Rats; Rats, Wistar | 2004 |
Dystonia induced by gabapentin.
Topics: Aged; Amines; Cyclohexanecarboxylic Acids; Dystonia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans | 2005 |
Presynaptic NMDA autoreceptors facilitate axon excitability: a new molecular target for the anticonvulsant gabapentin.
Topics: Amines; Analysis of Variance; Animals; Anticonvulsants; Axons; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neural Inhibition; Phosphinic Acids; Picrotoxin; Potassium Chloride; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic | 2005 |
Gabapentin-induced myoclonus in end-stage renal disease.
Topics: Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Male; Middle Aged; Myoclonus; Pain; Paresthesia; Spasm | 2005 |
Asterixis related to gabapentin as a cause of falls.
Topics: Accidental Falls; Aged; Amines; Analgesics; Breast Neoplasms; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dyskinesia, Drug-Induced; Fatal Outcome; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Neoplasm Metastasis; Risk Factors | 2005 |
Gabapentin fails to alter P/Q-type Ca2+ channel-mediated synaptic transmission in the hippocampus in vitro.
Topics: Amines; Animals; Calcium Channel Blockers; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; Neural Inhibition; Neural Pathways; omega-Conotoxin GVIA; omega-Conotoxins; Organ Culture Techniques; Presynaptic Terminals; Protein Subunits; Rats; Rats, Inbred Strains; Spinal Cord; Synaptic Transmission | 2005 |
Role of descending noradrenergic system and spinal alpha2-adrenergic receptors in the effects of gabapentin on thermal and mechanical nociception after partial nerve injury in the mouse.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Foot; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hot Temperature; Hyperalgesia; Male; Mice; Mice, Inbred Strains; Motor Activity; Pain Measurement; Prazosin; Receptors, Adrenergic, alpha-2; Sciatic Nerve; Touch; Yohimbine | 2005 |
Oral treatment with PD-0200347, an alpha2delta ligand, reduces the development of experimental osteoarthritis by inhibiting metalloproteinases and inducible nitric oxide synthase gene expression and synthesis in cartilage chondrocytes.
Topics: Administration, Oral; Amines; Animals; Cartilage, Articular; Chondrocytes; Cyclohexanecarboxylic Acids; Disease Models, Animal; Disease Progression; Dogs; Gabapentin; gamma-Aminobutyric Acid; Gene Expression; Immunohistochemistry; Metalloproteases; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Osteoarthritis; Pregabalin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
The use of lamotrigine, vigabatrin and gabapentin as add-on therapy in intractable epilepsy of childhood.
Topics: Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Tolerance; Epilepsies, Partial; Epilepsy, Generalized; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Infant, Newborn; Lamotrigine; Male; Retrospective Studies; Triazines; Vigabatrin | 2005 |
Complex regional pain syndrome involving the lower extremity: a report of 2 cases of sphenopalatine block as a treatment option.
Topics: Adult; Amines; Anticonvulsants; Autonomic Nerve Block; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Facial Neuralgia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Measurement; Physical Therapy Modalities | 2005 |
Effects of the antiepileptic drugs lamotrigine, topiramate and gabapentin on hERG potassium currents.
Topics: Amines; Anticonvulsants; Cell Line; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Stimulation; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Inhibitory Concentration 50; Lamotrigine; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Topiramate; Triazines | 2005 |
Antiepileptic medications in multiple sclerosis: adverse effects in a three-year follow-up study.
Topics: Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Middle Aged; Multiple Sclerosis; Triazines | 2005 |
Comparison of the antinociceptive profiles of gabapentin and 3-methylgabapentin in rat models of acute and persistent pain: implications for mechanism of action.
Topics: Acetates; Acute Disease; Amines; Analgesics; Animals; Benzylamines; Chronic Disease; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Pain; Phosphinic Acids; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2005 |
Effect of calcium channel modulators on temperature regulation in ovariectomized rats.
Topics: Amines; Animals; Body Temperature Regulation; Calcium Channel Blockers; Calcium Channels; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Morphine Dependence; Nifedipine; Norethynodrel; Ovariectomy; Rats; Substance Withdrawal Syndrome; Verapamil | 2005 |
Quantitative determination of vigabatrin and gabapentin in human serum by gas chromatography-mass spectrometry.
Topics: Amines; Calibration; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Sensitivity and Specificity; Vigabatrin | 2005 |
A fatality involving metaxalone.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Liver; Middle Aged; Muscle Relaxants, Central; Oxazolidinones; Suicide | 2005 |
[Brachioradial pruritus: a rare, localized, neuropathic form of itching].
Topics: Amines; Anticonvulsants; Cervical Vertebrae; Cyclohexanecarboxylic Acids; Female; Forearm; Gabapentin; gamma-Aminobutyric Acid; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Middle Aged; Myelography; Nerve Compression Syndromes; Pruritus; Skin Diseases, Papulosquamous; Spinal Nerve Roots; Spinal Osteophytosis | 2006 |
Novel role for gabapentin in neuroprotection of central nervous system in streptozotocine-induced diabetic rats.
Topics: Amines; Animals; Brain; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Gabapentin; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Nerve Growth Factors; Neuroprotective Agents; Phosphopyruvate Hydratase; Random Allocation; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; S100 Proteins | 2005 |
The novel GABA adamantane derivative (AdGABA): design, synthesis, and activity relationship with gabapentin.
Topics: Acetates; Adamantane; Amines; Analgesics; Animals; Anticonvulsants; Calcium Channels; Cell Line; Cell Membrane; Cyclohexanecarboxylic Acids; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Models, Animal; Molecular Structure; Pentylenetetrazole; Rats; Semicarbazides; Structure-Activity Relationship | 2005 |
Responsiveness of life-threatening refractory emesis to gabapentin-scopolamine therapy following posterior fossa surgery. Case report.
Topics: Amines; Antiemetics; Cholesteatoma; Cranial Fossa, Posterior; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Postoperative Complications; Scopolamine; Vomiting | 2005 |
Combination therapy for neuropathic pain--which drugs, which combination, which patients?
Topics: Amines; Analgesia; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia | 2005 |
Isaacs' syndrome (autoimmune neuromyotonia) in a patient with systemic lupus erythematosus.
Topics: Amines; Anticonvulsants; Autoantibodies; Azathioprine; Clonazepam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Isaacs Syndrome; Lupus Erythematosus, Systemic; Lupus Nephritis; Middle Aged; Potassium Channels, Voltage-Gated; Prednisone | 2005 |
Structure-activity relationships of pregabalin and analogues that target the alpha(2)-delta protein.
Topics: Amines; Amino Acid Transport System L; Analgesics; Animals; Anti-Anxiety Agents; Anticonvulsants; Brain; Calcium Channels; CHO Cells; Cricetinae; Cricetulus; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Leucine; Male; Mice; Mice, Inbred DBA; Pregabalin; Protein Binding; Protein Subunits; Rats; Structure-Activity Relationship; Swine | 2005 |
[Glossopharyngeal neuralgia. A propos of one clinical case].
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Glossopharyngeal Nerve; Glossopharyngeal Nerve Diseases; Humans | 2005 |
Gabapentin in the treatment of antipsychotic-induced akathisia in schizophrenia.
Topics: Adult; Akathisia, Drug-Induced; Amines; Antipsychotic Agents; Cholinergic Antagonists; Cyclohexanecarboxylic Acids; Diazepam; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Muscle Relaxants, Central; Schizophrenia, Paranoid | 2005 |
Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Ataxia; Behavior, Animal; Benzoxazines; Binding, Competitive; Catalepsy; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Cyclohexanecarboxylic Acids; Cyclohexanols; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunosuppressive Agents; Indoles; Indomethacin; Inflammation; Male; Mice; Mice, Knockout; Morpholines; Naphthalenes; Pain; Pain Measurement; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Cannabinoid, CB2; Time Factors | 2005 |
Effect of systemic and intrathecal gabapentin on allodynia in a new rat model of postherpetic neuralgia.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Diterpenes; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Injections, Intravenous; Injections, Spinal; Male; Mechanoreceptors; Neuralgia; Nociceptors; Pain Threshold; Rats; Rats, Sprague-Dawley; Touch | 2005 |
Novel cyclopropyl beta-amino acid analogues of pregabalin and gabapentin that target the alpha2-delta protein.
Topics: Administration, Oral; Amines; Amino Acid Transport System L; Amino Acids; Animals; Anticonvulsants; Biological Transport, Active; Blood-Brain Barrier; Calcium Channels; CHO Cells; Cricetinae; Cricetulus; Cyclization; Cyclohexanecarboxylic Acids; Cyclopropanes; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Injections, Intraventricular; Ion Channel Gating; Male; Mice; Mice, Inbred DBA; Nitriles; Pregabalin; Protein Subunits; Rats; Rats, Sprague-Dawley; Swine | 2005 |
Neuropathic pain following multilevel surgery in children with cerebral palsy: a case series and review.
Topics: Adolescent; Amines; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Cerebral Palsy; Child; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Male; Orthopedic Procedures; Pain Measurement; Pain, Postoperative; Patient Care Team; Peripheral Nervous System Diseases; Physical Therapy Modalities; Psychotherapy; Quadriplegia; Transcutaneous Electric Nerve Stimulation | 2005 |
Antinociceptive interactions between intrathecal gabapentin and MK801 or NBQX in rat formalin test.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Spinal; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate | 2005 |
Effects of amitriptyline and gabapentin on bilateral hyperalgesia observed in an animal model of unilateral axotomy.
Topics: Amines; Amitriptyline; Animals; Anticonvulsants; Antidepressive Agents; Axotomy; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Mice; Morphine; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Species Specificity; Treatment Outcome | 2005 |
Comment on: Gilron I, Orr E, Tu D, O'Neill JP, Zamora JE, Bell AC. A placebo-controlled randomized clinical trial of perioperative administration of gabapentin, rofecoxib and their combination for spontaneous and movement-evoked pain after abdominal hyste
Topics: Adult; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Cyclooxygenase Inhibitors; Data Interpretation, Statistical; Double-Blind Method; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Lactones; Male; Middle Aged; Movement; Pain Measurement; Pain, Postoperative; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity; Sulfones; Surveys and Questionnaires; Treatment Outcome | 2005 |
Gabapentin for uraemic pruritus.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pruritus; Uremia | 2005 |
Behavioral, pharmacological and molecular characterization of the saphenous nerve partial ligation: a new model of neuropathic pain.
Topics: Amines; Amitriptyline; Analgesics; Animals; Behavior, Animal; Benzoxazines; Blotting, Western; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Ligation; Lumbosacral Region; Male; Morpholines; Naphthalenes; Neuralgia; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Opioid, mu; Sciatic Nerve; Skin | 2005 |
Effect of L-type calcium channel antagonists on spermine-induced CNS excitation in vivo.
Topics: Amines; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Central Nervous System; Convulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Mice; Neurodegenerative Diseases; Neurons; Nisoldipine; Nitrendipine; Spermine; Synapses; Synaptic Transmission; Verapamil | 2005 |
Use of gabapentin for rest pain in chronic critical limb ischemia.
Topics: Amines; Analgesics; Bed Rest; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ischemia; Leg; Low Back Pain; Male; Middle Aged | 2005 |
Synergic antinociceptive interaction between tramadol and gabapentin after local, spinal and systemic administration.
Topics: Administration, Oral; Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Female; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Rats; Rats, Wistar; Time Factors; Tramadol | 2005 |
Behavioral and pharmacological characterization of a distal peripheral nerve injury in the rat.
Topics: Amines; Analgesics; Animals; Cold Temperature; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Pain Measurement; Peripheral Nerve Injuries; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Reaction Time; Sciatic Neuropathy; Tibial Nerve; Touch | 2005 |
Synergistic interaction of gabapentin and oxcarbazepine in the mouse maximal electroshock seizure model--an isobolographic analysis.
Topics: Amines; Animals; Anticonvulsants; Brain; Carbamazepine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Electroshock; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Oxcarbazepine; Psychomotor Performance; Seizures | 2005 |
Chronic cough as a sign of laryngeal sensory neuropathy: diagnosis and treatment.
Topics: Adolescent; Adult; Aged; Amines; Analgesics; Cough; Cyclohexanecarboxylic Acids; Deglutition Disorders; Electromyography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Laryngeal Nerve Injuries; Laryngeal Nerves; Laryngismus; Male; Middle Aged; Prospective Studies; Stroboscopy; Video Recording; Vocal Cord Paralysis | 2005 |
Gabapentin withdrawal syndrome in the presence of a taper.
Topics: Aged; Aged, 80 and over; Amines; Antimanic Agents; Bipolar Disorder; Chest Pain; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypertension; Substance Withdrawal Syndrome; Time Factors | 2005 |
Postoperative opioid sparing to hasten recovery: what are the issues?
Topics: Amines; Analgesics, Opioid; Anesthesia Recovery Period; Cyclohexanecarboxylic Acids; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative | 2005 |
Effects of gabapentin on spontaneous discharges and subthreshold membrane potential oscillation of type A neurons in injured DRG.
Topics: Amines; Analgesics; Animals; Animals, Newborn; Cyclohexanecarboxylic Acids; Differential Threshold; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Female; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Male; Membrane Potentials; Nerve Crush; Nerve Fibers; Neural Inhibition; Neurons; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Carboxylate bioisosteres of gabapentin.
Topics: Amines; Animals; Anticonvulsants; Carboxylic Acids; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Mice, Inbred DBA; Molecular Structure; Rats; Stereoisomerism; Structure-Activity Relationship; Tetrazoles | 2006 |
Post cardiac surgery diaphragmatic spasm successfully treated with gabapentin.
Topics: Aged, 80 and over; Amines; Anti-Anxiety Agents; Aortic Valve Stenosis; Cyclohexanecarboxylic Acids; Diaphragm; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Valve Prosthesis Implantation; Humans; Spasm | 2006 |
Antiepileptic drugs for the elderly: using the old to focus on the new.
Topics: Age Factors; Aged; Aged, 80 and over; Amines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Patient Compliance; Randomized Controlled Trials as Topic; Treatment Outcome; Triazines | 2005 |
Gabapentin-induced myopathy in 2 patients on short daily hemodialysis.
Topics: Adult; Amines; Anticonvulsants; Atorvastatin; Calcium Channels; Comorbidity; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glomerulonephritis; Glomerulonephritis, Membranoproliferative; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Neuromuscular Diseases; Peritoneal Dialysis; Physical Exertion; Postoperative Complications; Pyrroles; Recurrence; Renal Dialysis; Restless Legs Syndrome | 2005 |
[Medication, steel or radiation? The appropriate strategy to treat facial neuralgia].
Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Decompression, Surgical; Diagnosis, Differential; Drug Therapy, Combination; Facial Neuralgia; Gabapentin; gamma-Aminobutyric Acid; Glossopharyngeal Nerve Diseases; Humans; Nerve Compression Syndromes; Outcome and Process Assessment, Health Care; Oxcarbazepine; Radiosurgery; Trigeminal Neuralgia | 2005 |
Evaluation of health status in epilepsy using the EQ-5D questionnaire: a prospective, observational, 6-month study of adjunctive therapy with anti-epileptic drugs.
Topics: Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Prospective Studies; Secondary Prevention; Sickness Impact Profile; Surveys and Questionnaires; Topiramate; Triazines; Vigabatrin | 2005 |
Morphine, gabapentin, or their combination for neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; Motivation; Neuralgia; Patient Compliance | 2005 |
The effect of antinociceptive drugs tested at different times after nerve injury in rats.
Topics: Amines; Analgesics; Animals; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Imipramine; Male; Pain; Pain Measurement; Peripheral Nerve Injuries; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Computed tomography guided lumbar sympathetic block for complex regional pain syndrome in a child: a case report and review.
Topics: Amines; Amitriptyline; Analgesics; Anesthetics, Local; Antidepressive Agents, Tricyclic; Autonomic Nerve Block; Back; Cerebral Palsy; Child; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Guanethidine; Humans; Infant, Newborn; Infant, Premature; Pain; Retroperitoneal Space; Sympatholytics; Tomography, X-Ray Computed; Transcutaneous Electric Nerve Stimulation | 2006 |
Morphine, gabapentin, or their combination for neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Nephropathies; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; Neuralgia; Neurologic Examination | 2005 |
C9 helices and ribbons in gamma-peptides: crystal structures of gabapentin oligomers.
Topics: Amines; Amino Acids; Crystallization; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen Bonding; Models, Molecular; Molecular Structure; Peptides; Protein Conformation; Protein Structure, Secondary | 2005 |
Does preemptive use of gabapentin have no effect on postoperative pain and morphine consumption following lumbar laminectomy and discectomy?
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diskectomy; Gabapentin; gamma-Aminobutyric Acid; Humans; Laminectomy; Morphine; Pain, Postoperative | 2005 |
Design, synthesis, and preliminary evaluation of gabapentin-pregabalin mutual prodrugs in relieving neuropathic pain.
Topics: Amines; Analgesics, Non-Narcotic; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Male; Molecular Structure; Pregabalin; Prodrugs; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy; Structure-Activity Relationship | 2005 |
Gonadotrophin-releasing hormone agonist treatment of aggression in Alzheimer's disease: a case report.
Topics: Aged; Aggression; Alzheimer Disease; Amines; Antipsychotic Agents; Benzodiazepines; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Gabapentin; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Goserelin; Humans; Male; Olanzapine; Propranolol; Quetiapine Fumarate; Risperidone; Testosterone; Trazodone; Treatment Outcome; Valproic Acid | 2005 |
Attenuation of morphine tolerance by intrathecal gabapentin is associated with suppression of morphine-evoked excitatory amino acid release in the rat spinal cord.
Topics: Amines; Analgesics; Analysis of Variance; Animals; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Tolerance; Excitatory Amino Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Microdialysis; Morphine; Morphine Dependence; Pain Measurement; Rats; Rats, Wistar; Spinal Cord; Time Factors | 2005 |
Effects of anticonvulsants on soman-induced epileptiform activity in the guinea-pig in vitro hippocampus.
Topics: Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Chlormethiazole; Clozapine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Levetiracetam; Male; Phenylcarbamates; Phenylenediamines; Piracetam; Propylene Glycols; Soman; Topiramate | 2005 |
Herpes zoster and the prevention of postherpetic neuralgia: beyond antiviral therapy.
Topics: Amines; Analgesics, Opioid; Anticonvulsants; Antiviral Agents; Calcium Channels; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Resistance, Viral; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia, Postherpetic; Secondary Prevention; Treatment Outcome | 2005 |
Gabapentin in dermatology.
Topics: Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lyme Neuroborreliosis; Male; Neuralgia; Pain Measurement; Pilot Projects; Risk Assessment; Treatment Outcome | 2005 |
Evidence that gabapentin reduces neuropathic pain by inhibiting the spinal release of glutamate.
Topics: Amines; Analgesics; Animals; Aspartic Acid; Chronic Disease; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Foot; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Injections, Intraperitoneal; Injections, Spinal; Male; Neuralgia; Rats; Rats, Long-Evans; Spinal Cord; Spinal Cord Compression | 2005 |
Characterization of pain and pharmacologic responses in an animal model of lumbar adhesive arachnoiditis.
Topics: Amines; Analgesics; Analgesics, Opioid; Animals; Arachnoiditis; Behavior, Animal; Cauda Equina; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Lumbosacral Region; Male; Morphine; Pain; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Tissue Adhesions; Vocalization, Animal | 2005 |
Occipital neuralgia secondary to respiratory tract infection.
Topics: Amines; Amitriptyline; Analgesics, Non-Narcotic; Carbamazepine; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Middle Aged; Neuralgia; Respiratory Tract Infections | 2005 |
Rapid quantification of gabapentin in human plasma by liquid chromatography/tandem mass spectrometry.
Topics: Amines; Anticonvulsants; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Humans; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Temperature; Time Factors | 2006 |
Carbamazepine encephalopathy masquerading as Creutzfeldt-Jakob disease.
Topics: Aged; Amines; Analgesics, Non-Narcotic; Atrophy; Basal Ganglia; Brain; Brain Damage, Chronic; Carbamazepine; Cognition Disorders; Creutzfeldt-Jakob Syndrome; Cyclohexanecarboxylic Acids; Dementia; Diagnosis, Differential; Diagnostic Errors; Disease Progression; Dyskinesia, Drug-Induced; Electroencephalography; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Male; Recovery of Function; Trigeminal Neuralgia | 2005 |
CHF3381, a novel antinociceptive agent, attenuates capsaicin-induced pain in rats.
Topics: Administration, Oral; Amines; Analgesics; Animals; Behavior, Animal; Capsaicin; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glycine; Hindlimb; Hyperalgesia; Indans; Male; Pain; Rats; Rats, Sprague-Dawley | 2005 |
Anti-nociception is selectively enhanced by parallel inhibition of multiple subtypes of monoamine transporters in rat models of persistent and neuropathic pain.
Topics: Amines; Analgesics; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Bupropion; Constriction; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Male; Morpholines; Motor Activity; Neurotransmitter Uptake Inhibitors; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reboxetine; Rotarod Performance Test; Spinal Cord Injuries; Vesicular Monoamine Transport Proteins | 2005 |
Isobolographic characterisation of interactions among selected newer antiepileptic drugs in the mouse pentylenetetrazole-induced seizure model.
Topics: Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Nipecotic Acids; Oxcarbazepine; Pentylenetetrazole; Seizures; Tiagabine | 2005 |
Gabapentin-induced severe myoclonus in a patient with impaired renal function.
Topics: Aged; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Diseases; Male; Myoclonus | 2006 |
Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin.
Topics: Amines; Amino Acid Sequence; Anticonvulsants; Binding Sites; Crystallization; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Cytosol; Dithiothreitol; Gabapentin; gamma-Aminobutyric Acid; Isoenzymes; Isoleucine; Lysine; Mitochondria; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Conformation; Sequence Homology, Amino Acid; Substrate Specificity; Transaminases; Valine | 2005 |
Unbiased membrane permeability parameters for gabapentin using boundary layer approach.
Topics: Algorithms; Amines; Animals; Anticonvulsants; Biological Transport; Cell Membrane Permeability; Cyclohexanecarboxylic Acids; Diffusion; Gabapentin; gamma-Aminobutyric Acid; Humans; Intestinal Absorption; Jejunum; Male; Phenolsulfonphthalein; Rats; Rats, Sprague-Dawley; Water | 2005 |
Spinal-supraspinal serotonergic circuits regulating neuropathic pain and its treatment with gabapentin.
Topics: Action Potentials; Amines; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Cell Count; Cell Death; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation; Hot Temperature; Immunohistochemistry; Male; Neurons; Ondansetron; Pain; Pain Measurement; Pain Threshold; Pokeweed Mitogens; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-1; Ribosome Inactivating Proteins, Type 1; Saporins; Serotonin; Serotonin Antagonists; Spinal Cord; Substance P; Time Factors | 2005 |
Neuropathies in the rheumatoid patient: a case of the heavy hand.
Topics: Amines; Arthritis, Rheumatoid; Cyclohexanecarboxylic Acids; Electromyography; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Humans; Middle Aged; Peripheral Nervous System Diseases; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2005 |
Development and expression of neuropathic pain in CB1 knockout mice.
Topics: Amines; Animals; Anticonvulsants; Behavior, Animal; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Head; Hyperalgesia; Male; Mice; Mice, Knockout; Pain; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Receptor, Cannabinoid, CB1; Sciatic Neuropathy | 2006 |
Cognitive deficits predict low treatment retention in cocaine dependent patients.
Topics: Adult; Amines; Cocaine-Related Disorders; Cognition Disorders; Cognitive Behavioral Therapy; Cyclohexanecarboxylic Acids; Demography; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuropsychological Tests; Patient Dropouts; Retention, Psychology; Secondary Prevention; Severity of Illness Index; Treatment Outcome | 2006 |
[Vestibular paroxysmia: clinical study and treatment of eight patients].
Topics: Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hearing Loss, Sensorineural; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Compression Syndromes; Retrospective Studies; Tinnitus; Vertigo; Vestibulocochlear Nerve | 2005 |
Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain.
Topics: Ambroxol; Amines; Analgesics; Animals; Behavior, Animal; Constriction, Pathologic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Inflammation; Ligation; Male; NAV1.8 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Pain; Pain Measurement; Rats; Rats, Wistar; Sciatic Neuropathy; Sodium Channel Blockers; Sodium Channels | 2005 |
Pharmacokinetics of gabapentin during delivery, in the neonatal period, and lactation: does a fetal accumulation occur during pregnancy?
Topics: Amines; Anticonvulsants; Breast Feeding; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fetal Blood; Fetus; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Infant, Newborn; Lactation; Large Neutral Amino Acid-Transporter 1; Maternal-Fetal Exchange; Milk, Human; Parturition; Placenta; Postpartum Period; Pregnancy; Pregnancy Complications | 2005 |
Use of oxcarbazepine to treat a pediatric patient with resistant complex regional pain syndrome.
Topics: Amines; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hip Joint; Humans; Male; Neuritis; Osteomyelitis; Oxcarbazepine; Pain, Intractable; Reflex Sympathetic Dystrophy; Sodium Channels; Staphylococcal Infections; Staphylococcus aureus; Tibia; Treatment Outcome | 2005 |
Varicella zoster virus induces neuropathic changes in rat dorsal root ganglia and behavioral reflex sensitisation that is attenuated by gabapentin or sodium channel blocking drugs.
Topics: Amines; Animals; Anticonvulsants; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Fluorescent Antibody Technique; Gabapentin; Galanin; gamma-Aminobutyric Acid; Ganglia, Spinal; Herpes Zoster; Herpesvirus 3, Human; Immediate-Early Proteins; Immunohistochemistry; Lamotrigine; Mexiletine; Neuralgia; Neuralgia, Postherpetic; Neurons, Afferent; Neuropeptide Y; Rats; Receptors, N-Methyl-D-Aspartate; Reflex; Sodium Channels; Trans-Activators; Triazines; Viral Envelope Proteins; Virus Latency | 2005 |
Epilepsy in children: the evidence for new antiepileptic drugs.
Topics: Amines; Anticonvulsants; Carbamazepine; Child; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Topiramate; Treatment Outcome; Triazines; United States | 2005 |
New antiepileptic drugs in practice--how do they perform in the real world?
Topics: Amines; Anticonvulsants; Controlled Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Long-Term Care; Patient Dropouts; Piracetam; Topiramate; Treatment Outcome; Triazines | 2005 |
The neurological safety of epidural gabapentin in rats: a light microscopic examination.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Injections, Epidural; Male; Rats; Rats, Sprague-Dawley; Spinal Cord | 2005 |
Improving seizure control in dogs with refractory epilepsy using gabapentin as an adjunctive agent.
Topics: Amines; Animals; Anticonvulsants; Bromides; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Dog Diseases; Dogs; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Phenobarbital; Potassium Compounds; Prospective Studies; Seizures; Treatment Outcome | 2005 |
The effects of diacerhein on mechanical allodynia in inflammatory and neuropathic models of nociception in mice.
Topics: Amines; Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Inflammation; Mice; Pain; Sciatic Neuropathy | 2005 |
Gabapentin-induced neurologic toxicities.
Topics: Acute Kidney Injury; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Nervous System Diseases; Neuralgia, Postherpetic | 2005 |
Differential pharmacological modulation of the spontaneous stimulus-independent activity in the rat spinal cord following peripheral nerve injury.
Topics: Action Potentials; Amines; Analgesics; Animals; Anticonvulsants; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Male; Morphine; Neurons; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors | 2006 |
A case of recurrent and migratory complex regional pain syndrome type I: Prevention by gabapentin.
Topics: Amines; Cyclohexanecarboxylic Acids; Edema; Foot Diseases; Gabapentin; gamma-Aminobutyric Acid; Humans; Knee; Male; Middle Aged; Reflex Sympathetic Dystrophy | 2006 |
Efficacy of gabapentin in the management of pruritus of unknown origin.
Topics: Aged; Aged, 80 and over; Amines; Antipruritics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pruritus; Treatment Outcome | 2005 |
The antiallodynic action target of intrathecal gabapentin: Ca2+ channels, KATP channels or N-methyl-d-aspartic acid receptors?
Topics: Adenosine Triphosphate; Amines; Animals; Calcium Channel Blockers; Calcium Channels; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Delivery Systems; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Pain Measurement; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2006 |
Oral gabapentin treatment for symptomatic Heimann-Bielschowsky phenomenon.
Topics: Administration, Oral; Amines; Cyclohexanecarboxylic Acids; Electronystagmography; Excitatory Amino Acid Antagonists; Eye Movements; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nystagmus, Pathologic; Visual Acuity | 2006 |
Gabapentin in the treatment of severe sweating experienced by advanced cancer patients.
Topics: Adult; Aged; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Italy; Male; Middle Aged; Neoplasms; Sweating | 2006 |
Centrally active nonhormonal hot flash therapies.
Topics: Amines; Antidepressive Agents; Antihypertensive Agents; Belladonna Alkaloids; Clonidine; Cyclohexanecarboxylic Acids; Drug Combinations; Ergotamines; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Methyldopa; Methysergide; Phenobarbital | 2005 |
Gabapentin: a new drug for postoperative pain?
Topics: Amines; Analgesia, Epidural; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative | 2006 |
[Unique children -- unique headaches. Case reports of pediatric headache patients from an outpatient children's pain department].
Topics: Amines; Analgesics; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Developing Countries; Female; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Male | 2006 |
Simple and sensitive liquid chromatographic method with fluorimetric detection for the analysis of gabapentin in human plasma.
Topics: Adult; Aged; Aged, 80 and over; Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Stability; Fluorometry; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Reproducibility of Results; Sensitivity and Specificity | 2006 |
Prevention and treatment of postherpetic neuralgia.
Topics: Adult; Amines; Anesthetics, Local; Antiviral Agents; Calcium Channel Blockers; Child, Preschool; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Lidocaine; Methylprednisolone; Neuralgia, Postherpetic | 2006 |
The nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway participates in the antiallodynic effect of spinal gabapentin.
Topics: Amines; Analgesics; Animals; Apamin; Carbazoles; Charybdotoxin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclohexanecarboxylic Acids; Diazoxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gabapentin; gamma-Aminobutyric Acid; Glyburide; Indazoles; Indoles; Injections, Spinal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Okadaic Acid; Oxadiazoles; Pain; Pinacidil; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Spinal Nerves; Stereoisomerism; Time Factors; Vasodilator Agents | 2006 |
Objective evidence for the reversibility of nerve injury in diabetic neuropathic cachexia.
Topics: Adult; Amines; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Cachexia; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoglycemic Agents; Insulin; Neural Conduction | 2006 |
[Polyarteritis nodosa - a "classical" case].
Topics: Amines; Biopsy; Cyclohexanecarboxylic Acids; Cyclophosphamide; Diagnosis, Differential; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lymphocytes; Methylprednisolone; Middle Aged; Polyarteritis Nodosa; Referral and Consultation; Sural Nerve | 2006 |
Economic evaluation of oral treatments for neuropathic pain.
Topics: Administration, Oral; Amines; Amitriptyline; Analgesics; Carbamazepine; Cohort Studies; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Decision Trees; Drug Costs; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Tramadol; Treatment Outcome | 2006 |
Nummular headache: first Italian case and therapeutic proposal.
Topics: Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Indomethacin; Italy; Middle Aged; Post-Traumatic Headache | 2006 |
The aetiology of chronic cough: a review of current theories for the otorhinolaryngologists.
Topics: Amines; Anticonvulsants; Chronic Disease; Cough; Cranial Nerve Diseases; Cyclohexanecarboxylic Acids; Electromyography; Gabapentin; gamma-Aminobutyric Acid; Humans; Laryngeal Nerves; Stroboscopy | 2006 |
Experience with gabapentin for neuropathic pain in adolescents: report of five cases.
Topics: Adolescent; Amines; Analgesics; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neoplasms; Neuralgia; Pain Measurement; Pain, Intractable | 2006 |
Adverse effects of gabapentin and lack of anti-allodynic efficacy of amitriptyline in the streptozotocin model of painful diabetic neuropathy.
Topics: Amines; Amitriptyline; Animals; Cognition Disorders; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Male; Maze Learning; Rats; Rats, Sprague-Dawley; Reaction Time; Streptozocin | 2006 |
Brain homocarnosine and seizure control of patients taking gabapentin or topiramate.
Topics: Adult; Amines; Anticonvulsants; Brain Chemistry; Carnosine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy, Complex Partial; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neocortex; Topiramate; Treatment Outcome; Visual Cortex | 2006 |
The effects of gabapentin and memantine in acquired and congenital nystagmus: a retrospective study.
Topics: Adolescent; Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Middle Aged; Multiple Sclerosis; Nystagmus, Congenital; Nystagmus, Pathologic; Retrospective Studies; Treatment Outcome; Vision Tests | 2006 |
Sensitive high-performance liquid chromatographic quantitation of gabapentin in human serum using liquid-liquid extraction and pre-column derivatization with 9-fluorenylmethyl chloroformate.
Topics: Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Stability; Fluorenes; Gabapentin; gamma-Aminobutyric Acid; Humans; Reproducibility of Results; Sensitivity and Specificity | 2006 |
Spinal alpha(2)-adrenergic and muscarinic receptors and the NO release cascade mediate supraspinally produced effectiveness of gabapentin at decreasing mechanical hypersensitivity in mice after partial nerve injury.
Topics: Adrenergic alpha-2 Receptor Antagonists; Amines; Analgesics; Animals; Atropine; Cholinesterases; Cyclohexanecarboxylic Acids; Enzyme Activation; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Idazoxan; Injections, Intraventricular; Male; Mice; Muscarinic Antagonists; Narcotic Antagonists; Neostigmine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Sciatic Nerve; Spinal Cord; Touch; Yohimbine | 2006 |
[Muscle cramp--what is at the bottom of it? Only a little strained or seriously sick?].
Topics: Age Factors; Aged; Amines; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Citric Acid; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Exercise; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Muscle Cramp; Muscle Relaxants, Central; Organometallic Compounds; Physical Therapy Modalities; Pregnancy; Quinine | 2006 |
Motor cortex stimulation for central pain following a traumatic brain injury.
Topics: Accidental Falls; Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Aphasia, Broca; Brain Injuries; Chronic Disease; Coma; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Electric Stimulation Therapy; Gabapentin; gamma-Aminobutyric Acid; Hemiplegia; Humans; Hyperalgesia; Male; Motor Cortex; Pain; Pain Management; Postoperative Complications; Pyramidal Tracts; Spinothalamic Tracts | 2006 |
Inhibition of the rat brain sodium channel Nav1.2 after prolonged exposure to gabapentin.
Topics: Action Potentials; Amines; Animals; Anticonvulsants; Brain; Cell Line; Cricetinae; Cricetulus; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; NAV1.2 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Patch-Clamp Techniques; Rats; Sodium Channels | 2006 |
Carboxylate bioisosteres of pregabalin.
Topics: Amines; Animals; Anticonvulsants; Binding Sites; Carboxylic Acids; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsy, Reflex; Gabapentin; gamma-Aminobutyric Acid; Mice; Mice, Inbred DBA; Molecular Structure; Pregabalin; Protein Subunits; Stereoisomerism; Structure-Activity Relationship | 2006 |
Gabapentin-induced coma in a patient with renal failure.
Topics: Administration, Oral; Amines; Coma; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Middle Aged; Risk Assessment; Sciatica | 2006 |
Possible activation of the NO-cyclic GMP-protein kinase G-K+ channels pathway by gabapentin on the formalin test.
Topics: 4-Aminopyridine; Amines; Analgesics; Animals; Apamin; Carbazoles; Charybdotoxin; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Glyburide; Indoles; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Tolbutamide | 2006 |
Use of antiepileptics and tricyclic antidepressants in cancer patients with neuropathic pain.
Topics: Aged; Amines; Amitriptyline; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neoplasms; Neuralgia | 2006 |
Sensitive microanalysis of gabapentin by high-performance liquid chromatography in human serum using pre-column derivatization with 4-chloro-7-nitrobenzofurazan: Application to a bioequivalence study.
Topics: 4-Chloro-7-nitrobenzofurazan; Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Therapeutic Equivalency | 2006 |
K(+)-evoked [(3)H]-norepinephrine release in human brain slices from epileptic and non-epileptic patients is differentially modulated by gabapentin and pinacidil.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Amines; Anticonvulsants; Brimonidine Tartrate; Calcium Channel Blockers; Child; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Humans; Idazoxan; In Vitro Techniques; Male; Middle Aged; Norepinephrine; omega-Conotoxins; Pinacidil; Potassium; Quinoxalines; Time Factors; Tritium | 2006 |
Gabapentin in the treatment of intractable idiopathic chronic cough: case reports.
Topics: Adult; Aged; Amines; Calcium Channel Blockers; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Treatment Outcome | 2006 |
Measuring the effects of antiepileptic medications on balance in older people.
Topics: Aged; Amines; Anticonvulsants; Ataxia; Carbamazepine; Cyclohexanecarboxylic Acids; Dizziness; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Postural Balance; Prospective Studies; Triazines; Vestibular Function Tests | 2006 |
Off-label prescribing among office-based physicians.
Topics: Adult; Amines; Amitriptyline; Anticonvulsants; Cardiovascular Agents; Cyclohexanecarboxylic Acids; Drug Labeling; Drug Prescriptions; Drug Utilization Review; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multivariate Analysis; Practice Patterns, Physicians'; United States; United States Food and Drug Administration | 2006 |
Inhibition of paclitaxel-induced A-fiber hypersensitization by gabapentin.
Topics: Amines; Animals; Antineoplastic Agents, Phytogenic; Behavior, Animal; Blotting, Western; Calcium Channels; Cyclohexanecarboxylic Acids; Electric Stimulation; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Immunohistochemistry; Ion Channel Gating; Male; Mice; Myelin Sheath; Nerve Fibers, Myelinated; Paclitaxel; Pain; Pain Measurement; Peripheral Nervous System Diseases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
Gabapentin may cause reversible visual field constriction.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Leg; Middle Aged; Pain; Scotoma | 2006 |
Evaluation of gabapentin and ethosuximide for treatment of acute nonconvulsive seizures following ischemic brain injury in rats.
Topics: Acute Disease; Amines; Animals; Brain Ischemia; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electroencephalography; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Seizures | 2006 |
Survey of management of acquired nystagmus in the United Kingdom.
Topics: Amines; Baclofen; Cyclohexanecarboxylic Acids; Drug Utilization; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Health Care Surveys; Humans; Multiple Sclerosis; Neoplasms; Neurology; Nystagmus, Pathologic; Ophthalmology; Professional Practice; Referral and Consultation; Stroke; Treatment Outcome; United Kingdom; Vestibular Diseases | 2007 |
Clinical presentation, quantitative sensory testing, and therapy of 2 patients with fourth thoracic syndrome.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Manipulation, Orthopedic; Middle Aged; Paresthesia; Thoracic Outlet Syndrome | 2006 |
Surgically induced osteoarthritis in the rat results in the development of both osteoarthritis-like joint pain and secondary hyperalgesia.
Topics: Amines; Analgesics; Animals; Arthralgia; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Lactones; Male; Osteoarthritis, Knee; Rats; Sulfones; Weight-Bearing | 2006 |
Pharmacologic treatment of congenital nystagmus.
Topics: Administration, Oral; Adult; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Eye Movements; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Nystagmus, Congenital; Visual Acuity | 2006 |
Isaacs' syndrome: clinical and electrophysiological response to gabapentin.
Topics: Action Potentials; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Electromyography; Gabapentin; gamma-Aminobutyric Acid; Humans; Isaacs Syndrome; Male; Middle Aged; Motor Neurons; Muscle Contraction; Muscle, Skeletal; Neuromuscular Junction; Spasm; Treatment Outcome | 2006 |
Determination of gabapentin in human plasma using hydrophilic interaction liquid chromatography with tandem mass spectrometry.
Topics: Amines; Anticonvulsants; Area Under Curve; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Therapeutic Equivalency; Water | 2006 |
Abnormal blink reflex studies in a patient with supraorbital neuralgia.
Topics: Adult; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Blinking; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Naproxen; Neuralgia; Orbit; Reflex, Abnormal; Treatment Outcome | 2006 |
Various GABA-mimetic drugs differently affect cocaine-evoked hyperlocomotion and sensitization.
Topics: Amines; Animals; Behavior, Animal; Brain; Cocaine; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agents; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Male; Motor Activity; Nipecotic Acids; Rats; Rats, Wistar; Tiagabine; Vigabatrin | 2006 |
Venlafaxine compromises the antinociceptive actions of gabapentin in rat models of neuropathic and persistent pain.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Cyclohexanols; Dose-Response Relationship, Drug; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Kidney; Male; Neuralgia; Pain; Pain Measurement; Rats; Rats, Inbred BN; Venlafaxine Hydrochloride | 2006 |
Gabapentin for the treatment of refractory dysesthetic pain after open cholecystectomy.
Topics: Amines; Analgesics; Cholecystectomy; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain, Intractable; Paresthesia | 2006 |
Gabapentin may cause reversible visual field constriction: GABA transaminase inhibitors may cause irreversible visual field loss.
Topics: 4-Aminobutyrate Transaminase; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Scotoma | 2006 |
Gabapentin may cause reversible visual field constriction: learning or inattention artefact a more likely explanation.
Topics: Amines; Analgesics; Attention; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Scotoma; Vision Tests | 2006 |
Evolving approaches in the treatment of menopausal symptoms.
Topics: Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Estrogen Replacement Therapy; Estrogens; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Practice Patterns, Physicians'; United States | 2006 |
Determination of gabapentin in human plasma and urine by high-performance liquid chromatography with UV-vis detection.
Topics: Amines; Anticonvulsants; Calibration; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Molecular Structure; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2006 |
Gabapentin has little or no effect in the treatment of burning mouth syndrome - results of an open-label pilot study.
Topics: Aged; Amines; Burning Mouth Syndrome; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pilot Projects; Treatment Failure | 2006 |
Gabapentin depresses C-fiber-evoked field potentials in rat spinal dorsal horn only after induction of long-term potentiation.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Long-Term Potentiation; Male; Morphine; Narcotics; Nerve Fibers; Neural Inhibition; Posterior Horn Cells; Rats; Rats, Wistar; Spinal Cord | 2006 |
Perioperative analgesia to prevent chronic postmastectomy pain.
Topics: Amines; Anesthetics, Local; Breast Neoplasms; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mastectomy; Pain, Postoperative | 2006 |
Gabapentin increases a tonic inhibitory conductance in hippocampal pyramidal neurons.
Topics: 4-Aminobutyrate Transaminase; Amines; Analgesics; Animals; Blotting, Western; Cyclohexanecarboxylic Acids; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Mice; Neural Conduction; Patch-Clamp Techniques; Pregnancy; Pyramidal Cells; Receptors, GABA-A; Receptors, GABA-B; Somatosensory Cortex; Synapses; Vigabatrin | 2006 |
Pulsed radiofrequency of the dorsal root ganglia is superior to pharmacotherapy or pulsed radiofrequency of the intercostal nerves in the treatment of chronic postsurgical thoracic pain.
Topics: Adult; Amines; Analgesics; Anticonvulsants; Carbamazepine; Catheter Ablation; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Fluoroscopy; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Humans; Male; Mastectomy; Middle Aged; Nortriptyline; Oxcarbazepine; Pain, Postoperative; Retrospective Studies; Thoracotomy; Treatment Outcome | 2006 |
The P/Q-type voltage-dependent calcium channel as pharmacological target in spinocerebellar ataxia type 6: gabapentin and pregabalin may be of therapeutic benefit.
Topics: Amines; Calcium Channel Blockers; Calcium Channels, P-Type; Calcium Channels, Q-Type; Cyclohexanecarboxylic Acids; Drug Delivery Systems; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Spinal Cord; Spinocerebellar Ataxias | 2007 |
Mirtazapine and gabapentin for reducing pruritus in cutaneous T-cell lymphoma.
Topics: Amines; Anticonvulsants; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lymphoma, T-Cell, Cutaneous; Mianserin; Mirtazapine; Mycosis Fungoides; Pruritus; Sezary Syndrome; Skin Neoplasms | 2006 |
Safeguarding patient welfare: who's in charge?
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Industry; Gabapentin; gamma-Aminobutyric Acid; Humans; Legislation, Drug; Marketing; United States; United States Food and Drug Administration | 2006 |
Gabapentin for postoperative pain relief.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative | 2006 |
Examination of the interaction between peripheral diclofenac and gabapentin on the 5% formalin test in rats.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Female; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Pain Measurement; Rats; Rats, Wistar | 2006 |
The calcium channel alpha2delta-2 subunit partitions with CaV2.1 into lipid rafts in cerebellum: implications for localization and function.
Topics: Alanine; Amines; Animals; Arginine; Calcium Channel Blockers; Calcium Channels; Calcium Channels, N-Type; Cell Line; Cerebellum; Cholesterol; Cyclohexanecarboxylic Acids; Electric Conductivity; Gabapentin; gamma-Aminobutyric Acid; Immunoprecipitation; Membrane Microdomains; Mice; Mutation; Nerve Tissue Proteins; Purkinje Cells; Tissue Distribution | 2006 |
Does acute pain associated with herpes zoster respond to treatment with gabapentin?
Topics: Acute Disease; Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Neuralgia; Pain; Randomized Controlled Trials as Topic; Treatment Outcome | 2006 |
Addition of gabapentin to a modified FOLFOX regimen does not reduce oxaliplatin-induced neurotoxicity.
Topics: Amines; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Cyclohexanecarboxylic Acids; Female; Fluorouracil; Gabapentin; gamma-Aminobutyric Acid; Humans; Leucovorin; Male; Neurons, Afferent; Organoplatinum Compounds; Oxaliplatin | 2006 |
Evaluation of clinically relevant glutamate pathway inhibitors in in vitro model of Huntington's disease.
Topics: Amines; Animals; Apoptosis; Cells, Cultured; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Folic Acid; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Huntington Disease; Lamotrigine; Male; Memantine; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Riluzole; Triazines | 2006 |
Bronchial involvement in the cramp-fasciculation syndrome.
Topics: Administration, Inhalation; Adolescent; Adult; Amines; Anti-Asthmatic Agents; Asthma, Exercise-Induced; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Motor Neurons; Muscle, Skeletal; Muscle, Smooth; Neuromuscular Diseases | 2006 |
Neurontin for Charles Bonnet Syndrome.
Topics: Amines; Central Nervous System Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hallucinations; Humans; Marketing of Health Services; Syndrome; United States; Vision, Low | 2006 |
Abdominal pain related to mitochondrial neurogastrointestinal encephalomyopathy syndrome may benefit from splanchnic nerve blockade.
Topics: Abdominal Pain; Adolescent; Amines; Analgesics; Anesthetics, Local; Cyclohexanecarboxylic Acids; Electromyography; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Humans; Magnetic Resonance Imaging; Male; Mitochondrial Encephalomyopathies; Nerve Block; Neurologic Examination; Paresthesia; Prilocaine; Radiography; Splanchnic Nerves | 2006 |
Gabapentin enhances the analgesic response to morphine in acute model of pain in male rats.
Topics: Amines; Analgesics, Opioid; Animals; Area Under Curve; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Male; Morphine; Pain; Rats; Rats, Wistar | 2006 |
Opposite effects of a single versus repeated doses of gabapentin on retention performance of an inhibitory avoidance response in mice.
Topics: Amines; Animals; Avoidance Learning; Behavior, Animal; Choline; Conditioning, Classical; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electroshock; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Inhibition, Psychological; Male; Mice; Muscarinic Agonists; Oxotremorine; Reaction Time; Tritium | 2007 |
Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus.
Topics: Amines; Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Muscarinic Agonists; N-Methylaspartate; Pilocarpine; Pimozide; Rats; Seizures; Status Epilepticus | 2006 |
Primary orthostatic tremor in a Scottish deerhound.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Dog Diseases; Dogs; Electromyography; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Muscles; Phenobarbital; Treatment Outcome; Tremor | 2006 |
Gabapentin in the operating room: clear for discharge?
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neurosurgical Procedures; Operating Rooms; Pain, Postoperative; Randomized Controlled Trials as Topic; Treatment Outcome | 2006 |
Effect of the administration of tiagabine and gabapentin on rabbit electroencephalogram activity.
Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electroencephalography; Female; Frontal Lobe; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; Metencephalon; Nipecotic Acids; Rabbits; Tiagabine | 2006 |
Gabapentin and breastfeeding: a case report.
Topics: Adult; Amines; Analgesics; Back Pain; Breast Feeding; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lactation; Male; Milk, Human | 2006 |
Off-label marketing stirs a legal hornet's nest.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Prescriptions; Gabapentin; gamma-Aminobutyric Acid; Humans; Liability, Legal; Marketing; Practice Patterns, Physicians'; Product Labeling; United States | 2006 |
Effects of gabapentin on morphine consumption and pain in severely burned patients.
Topics: Administration, Oral; Amines; Analgesics; Burns; Case-Control Studies; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Morphine; Pain; Pain Measurement; Treatment Outcome | 2007 |
Comparative effects of some hydrophilic excipients on the rate of gabapentin and baclofen lactamization in lyophilized formulations.
Topics: Amines; Anticonvulsants; Baclofen; beta-Cyclodextrins; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Drug Stability; Excipients; Freeze Drying; Gabapentin; gamma-Aminobutyric Acid; Humidity; Kinetics; Lactams; Lactose; Mannitol; Models, Chemical; Molecular Structure; Parasympatholytics; Povidone; Raffinose; Technology, Pharmaceutical; Temperature; Thermogravimetry; Trehalose; Water | 2007 |
Inhibitory effect of gabapentin on N-methyl-D-aspartate receptors expressed in Xenopus oocytes.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA-A Receptor Antagonists; Gabapentin; gamma-Aminobutyric Acid; Oocytes; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Xenopus laevis | 2007 |
The effect of combined administration of ethanol and gabapentin on rabbit electroencephalographic activity.
Topics: Amines; Animals; Anticonvulsants; Brain; Central Nervous System Depressants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Ethanol; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; Rabbits | 2006 |
Bilateral hemifacial spasm and trigeminal neuralgia: a unique form of painful tic convulsif.
Topics: Aged; Amines; Amitriptyline; Analgesics; Arachnoid Cysts; Botulinum Toxins, Type A; Cyclohexanecarboxylic Acids; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Hemifacial Spasm; Humans; Magnetic Resonance Imaging; Male; Neuromuscular Agents; Pain; Tic Disorders; Trigeminal Neuralgia | 2007 |
Chemotherapy-evoked painful peripheral neuropathy: analgesic effects of gabapentin and effects on expression of the alpha-2-delta type-1 calcium channel subunit.
Topics: Amines; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation; Male; Motor Activity; Neuralgia; Paclitaxel; Pain Measurement; Protein Subunits; Rats; Rats, Sprague-Dawley; Time Factors; Vincristine | 2007 |
Dyskinesia induced by gabapentin in idiopathic Parkinson's disease.
Topics: Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Dyskinesia, Drug-Induced; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Parkinson Disease | 2007 |
[This is the anaesthetist's fault! (About the post-anaesthetic consultation)].
Topics: Accidental Falls; Acromioclavicular Joint; Adult; Amines; Analgesia; Anesthesia, Local; Anesthesiology; Benzodiazepines; Brachial Plexus Neuropathies; Catheterization; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Gabapentin; gamma-Aminobutyric Acid; Humans; Joint Dislocations; Male; Muscle Weakness; Off-Road Motor Vehicles; Pain, Postoperative; Postoperative Care; Postoperative Complications; Somatoform Disorders | 2007 |
Focal myelomalacia and syrinx formation after accidental intramedullary lidocaine injection during lumbar anesthesia: a report of 3 cases.
Topics: Adult; Amines; Anesthesia, Spinal; Anesthetics, Local; Carbamazepine; Cesarean Section; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Lidocaine; Lumbosacral Region; Magnetic Resonance Imaging; Spinal Cord Diseases | 2006 |
Cardiac conduction disturbances after an overdose of nefazodone and gabapentin.
Topics: Adult; Amines; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Cyclohexanecarboxylic Acids; Drug Overdose; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Piperazines; Tachycardia, Sinus; Triazoles | 2006 |
[Gabapentin treatment in a female patient with panic disorder and adverse effects under carbamazepine during benzodiazepine withdrawal].
Topics: Aged; Alprazolam; Amines; Antimanic Agents; Benzodiazepines; Carbamazepine; Chemical and Drug Induced Liver Injury; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Liver Function Tests; Panic Disorder; Substance Withdrawal Syndrome | 2007 |
Neurochemical evidence that supraspinally administered gabapentin activates the descending noradrenergic system after peripheral nerve injury.
Topics: Amines; Analgesics; Animals; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Injections, Intraventricular; Injections, Spinal; Male; Methoxyhydroxyphenylglycol; Mice; Norepinephrine; Pain; Pain Measurement; Sciatic Nerve; Sciatic Neuropathy; Serotonin; Spinal Cord | 2007 |
Persistent primary thunderclap headache responsive to gabapentin.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders, Primary; Humans; Middle Aged | 2006 |
[Post-operative pain therapy of a chronic pain patient].
Topics: Adult; Amines; Analgesics; Analgesics, Opioid; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Combinations; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Male; Muscle Relaxants, Central; Oxycodone; Pain, Postoperative; Tolperisone; Treatment Outcome | 2006 |
Anticonvulsant hypersensitivity syndrome: cross-reactivity with tricyclic antidepressant agents.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Benzodiazepines; Carbamazepine; Cross Reactions; Cyclohexanecarboxylic Acids; Doxepin; Drug Hypersensitivity; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Molecular Structure; Phenytoin; Skin Tests; Syndrome; Valproic Acid | 2006 |
Chronic cough as a sign of laryngeal sensory neuropathy: diagnosis and treatment.
Topics: Amines; Chronic Disease; Cough; Cranial Nerve Diseases; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Electromyography; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Laryngeal Nerves; Treatment Outcome | 2006 |
Painful pemphigus vulgaris.
Topics: Administration, Cutaneous; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain; Pemphigus; Treatment Outcome | 2007 |
PEPT1 enhances the uptake of gabapentin via trans-stimulation of b0,+ exchange.
Topics: Amines; Amino Acid Transport Systems; Amino Acids; Animals; Arginine; Biological Transport, Active; Cyclohexanecarboxylic Acids; Dipeptides; Gabapentin; gamma-Aminobutyric Acid; Glucose; Glutamate-Ammonia Ligase; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines; Lysine; Male; Peptide Transporter 1; Rats; Rats, Sprague-Dawley; Sodium; Symporters; Water | 2007 |
Cognitive function impairment in patients with neuropathic pain under standard conditions of care.
Topics: Adult; Aged; Amines; Analgesics; Cognition Disorders; Cohort Studies; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Prevalence; Psychological Tests; Somatosensory Disorders | 2007 |
Further characterization of a rat model of varicella zoster virus-associated pain: Relationship between mechanical hypersensitivity and anxiety-related behavior, and the influence of analgesic drugs.
Topics: Amines; Analgesics; Animals; Anti-Anxiety Agents; Anxiety Disorders; Cells, Cultured; Cyclohexanecarboxylic Acids; Disease Models, Animal; Fibroblasts; Gabapentin; gamma-Aminobutyric Acid; Herpesvirus 3, Human; Hyperalgesia; Male; Motor Activity; Neuralgia, Postherpetic; Nociceptors; Pain Measurement; Pain Threshold; Peripheral Nerves; Physical Stimulation; Rats; Rats, Wistar; Viral Load | 2007 |
Use of gabapentin during pregnancy to reduce brain damage in new-born infants that are premature or at risk of perinatal asphyxia.
Topics: Amines; Asphyxia Neonatorum; Brain Damage, Chronic; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Infant, Premature; Models, Biological; Pregnancy; Risk Factors | 2007 |
Uremic pruritus.
Topics: Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Capsaicin; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Nutrition Assessment; Pruritus; Renal Dialysis; Serotonin Antagonists | 2006 |
Cost-effectiveness of pregabalin for the management of neuropathic pain associated with diabetic peripheral neuropathy and postherpetic neuralgia: a Canadian perspective.
Topics: Amines; Analgesics; Canada; Clinical Trials as Topic; Costs and Cost Analysis; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Data Collection; Diabetic Neuropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Models, Theoretical; Neuralgia, Postherpetic; Predictive Value of Tests; Pregabalin; Time Factors | 2006 |
Gabapentin-related changes in renal function: two case reports.
Topics: Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Diabetes Insipidus, Nephrogenic; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nephritis, Interstitial | 2007 |
A comparison of the glutamate release inhibition and anti-allodynic effects of gabapentin, lamotrigine, and riluzole in a model of neuropathic pain.
Topics: Amines; Analgesics; Animals; Anticonvulsants; Cold Temperature; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Hyperalgesia; Lamotrigine; Male; Microdialysis; Pain; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Long-Evans; Riluzole; Spinal Cord; Touch; Triazines | 2007 |
Diverse effects of GABA-mimetic drugs on cocaine-evoked self-administration and discriminative stimulus effects in rats.
Topics: Amines; Animals; Behavior, Animal; Cocaine; Cyclohexanecarboxylic Acids; Discrimination Learning; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Nipecotic Acids; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Tiagabine; Vigabatrin | 2007 |
Primary and secondary red ear syndrome: implications for treatment.
Topics: Aged; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Ear Diseases; Erythema; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ibuprofen; Indomethacin; Middle Aged; Temporomandibular Joint Disorders; Trigeminal Autonomic Cephalalgias | 2007 |
New device to control combined lingual and palatal myoclonus.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Clonazepam; Cyclohexanecarboxylic Acids; Eye Movements; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Male; Myoclonus; Technology, Dental; Tongue; Valproic Acid | 2007 |
Dynamics of neuronal assemblies are modulated by anaesthetics but not analgesics.
Topics: Amines; Analgesics; Anesthetics, Intravenous; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Microscopy, Fluorescence; Morphine; Nerve Net; Propofol; Pyridinium Compounds; Rats; Rats, Wistar; Synaptic Transmission; Thiopental; Time Factors | 2007 |
Gabapentin successfully manages chronic unexplained irritability in children with severe neurologic impairment.
Topics: Adolescent; Adult; Amines; Analgesics; Child; Child, Preschool; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Irritable Mood; Male; Nervous System Diseases; Remission Induction; Retrospective Studies; Severity of Illness Index | 2007 |
Development and application of a validated HPLC method for the determination of gabapentin and its major degradation impurity in drug products.
Topics: Amines; Analgesics; Anticonvulsants; Capsules; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Contamination; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets; Technology, Pharmaceutical | 2007 |
Laryngeal neuropathy as a cause of chronic intractable cough.
Topics: Amines; Cough; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Laryngeal Nerves; Peripheral Nervous System Diseases | 2007 |
[Intensified insulin therapy plus antineuritic medication is more effective than antineuritics alone in painful diabetic neuropathy].
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Amines; Analgesics; Clomipramine; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Longitudinal Studies; Male; Middle Aged; Neuralgia; Nortriptyline; Retrospective Studies | 2006 |
Nociception: Taking the Pain out of Drug Discovery. 28 November 2006, London, UK.
Topics: Amidohydrolases; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; NAV1.9 Voltage-Gated Sodium Channel; Neuropeptides; Nociceptors; Pain; Peripheral Nervous System Diseases; Receptor, Cannabinoid, CB2; Receptors, Metabotropic Glutamate; Sodium Channels; TRPV Cation Channels | 2007 |
The promotion of gabapentin.
Topics: Amines; Cyclohexanecarboxylic Acids; Drug Industry; Gabapentin; gamma-Aminobutyric Acid; Marketing; Publishing; Research | 2007 |
The promotion of gabapentin.
Topics: Amines; Cyclohexanecarboxylic Acids; Drug Industry; Gabapentin; gamma-Aminobutyric Acid; Marketing; Publishing; Research | 2007 |
The promotion of gabapentin.
Topics: Amines; Cyclohexanecarboxylic Acids; Drug Industry; Gabapentin; gamma-Aminobutyric Acid; Marketing; Publishing; Research | 2007 |
Abuse, dependency and withdrawal with gabapentin: a first case report.
Topics: Aged; Alcoholism; Amines; Antimanic Agents; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mood Disorders; Substance Withdrawal Syndrome; Substance-Related Disorders | 2007 |
Gabapentin use in chronic uraemic itch is in line with emerging pathogenetic hypothesis.
Topics: Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pruritus; Uremia | 2007 |
Isobolographic analysis of interaction between drugs with nonparallel dose-response relationship curves: a practical application.
Topics: Amines; Animals; Anticonvulsants; Behavior, Animal; Brain; Brain Chemistry; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Electroshock; Fructose; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Mice; Models, Biological; Motor Skills Disorders; Neuroprotective Agents; Regression Analysis; Seizures; Time Factors; Topiramate | 2007 |
Hybrid peptide design. Hydrogen bonded conformations in peptides containing the stereochemically constrained gamma-amino acid residue, gabapentin.
Topics: Amines; Amino Acids; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Cyclohexanes; Gabapentin; gamma-Aminobutyric Acid; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Peptides; Stereoisomerism | 2007 |
Antihyperalgesic efficacy of lacosamide in a rat model for muscle pain induced by TNF.
Topics: Acetamides; Amines; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Hyperalgesia; Lacosamide; Male; Muscular Diseases; Pain; Pregabalin; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factors | 2007 |
Alpha-2-delta ligands for singultus (hiccup) treatment: three case reports.
Topics: Aged; Amines; Anticonvulsants; Calcium Channels; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Ligands; Male; Middle Aged; Pregabalin | 2007 |
Intraventricular administration of gabapentin in the rat increases flurothyl seizure threshold.
Topics: Amines; Animals; Anticonvulsants; Brain; Brain Chemistry; Cerebral Cortex; Convulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Epilepsy; Flurothyl; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraventricular; Methylene Blue; Nerve Fibers, Myelinated; Rats; Rats, Sprague-Dawley; Seizures; Staining and Labeling; Time Factors; Treatment Outcome | 2007 |
In vivo effects of glycyl-glutamate and glycyl-sarcosine on gabapentin oral absorption in rat.
Topics: Administration, Oral; Amines; Amino Acid Transport Systems; Analgesics; Analysis of Variance; Animals; Area Under Curve; Biological Availability; Cyclohexanecarboxylic Acids; Dipeptides; Gabapentin; gamma-Aminobutyric Acid; Intestinal Absorption; Male; Rats; Rats, Sprague-Dawley | 2007 |
The importance of genetic background on pain behaviours and pharmacological sensitivity in the rat spared serve injury model of peripheral neuropathic pain.
Topics: Amines; Analgesics; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Isoxazoles; Male; Morphine; Neuralgia; Pain Measurement; Pain Threshold; Peripheral Nerve Injuries; Pharmacogenetics; Rats; Rats, Inbred BN; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; Reproducibility of Results; Species Specificity | 2007 |
Gabapentin abuse, and delirium tremens upon gabapentin withdrawal.
Topics: Adult; Alcohol Withdrawal Delirium; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2007 |
Isobolographic analyses of the gabapentin-metamizol combination after local peripheral, intrathecal and oral administration in the rat.
Topics: Administration, Cutaneous; Administration, Oral; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dipyrone; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Pain; Rats; Rats, Wistar | 2007 |
Evaluation of gabapentin in the treatment of generalized vulvodynia, unprovoked.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain; Retrospective Studies; Treatment Outcome; Vulvar Diseases | 2007 |
Postoperative pain management--is there a role for gabapentin or pregabalin?
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Pregabalin | 2007 |
Antinociceptive efficacy of lacosamide in rat models for tumor- and chemotherapy-induced cancer pain.
Topics: Acetamides; Amines; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Lacosamide; Neuralgia; Pain, Intractable; Rats; Rats, Sprague-Dawley; Vincristine | 2007 |
Effects of phenytoin and carbamazepine on calcium transport in Caco-2 cells.
Topics: Amines; Anticonvulsants; Biological Transport, Active; Bone Diseases; Caco-2 Cells; Calcium; Carbamazepine; Cell Membrane Permeability; Cyclohexanecarboxylic Acids; Epithelial Cells; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenytoin; Topiramate; Vitamin D | 2007 |
[Gabapentin-induced central hypoventilation].
Topics: Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoventilation | 2007 |
Gabapentin relieves post-dural puncture headache--a report of two cases.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Post-Dural Puncture Headache | 2007 |
Treatment of cervical myelopathy in patients with the fibromyalgia syndrome: outcomes and implications.
Topics: Adult; Amines; Analgesics; Case-Control Studies; Cervical Vertebrae; Cyclohexanecarboxylic Acids; Decompression, Surgical; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Humans; Male; Middle Aged; Physical Therapy Modalities; Prospective Studies; Quality of Life; Spinal Cord Diseases; Treatment Outcome | 2007 |
Pregabalin and duloxetine for the treatment of neuropathic pain disorders.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain; Pregabalin; Randomized Controlled Trials as Topic; Thiophenes | 2007 |
Gabapentin in the management of dysautonomia following severe traumatic brain injury: a case series.
Topics: Adolescent; Adult; Amines; Anticonvulsants; Autonomic Nervous System Diseases; Brain Injuries; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Treatment Outcome | 2007 |
Role of spinal voltage-dependent calcium channel alpha 2 delta-1 subunit in the expression of a neuropathic pain-like state in mice.
Topics: Amines; Analgesics; Animals; Calcium Channels; Cells, Cultured; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Gene Expression; Injections, Spinal; Male; Mice; Pain Measurement; Pain Threshold; Protein Subunits; RNA, Messenger; Sciatica; Up-Regulation | 2007 |
Characteristics and impact of drug detailing for gabapentin.
Topics: Amines; Cyclohexanecarboxylic Acids; Drug Industry; Gabapentin; gamma-Aminobutyric Acid; Humans; Marketing; Physicians | 2007 |
Novel inhibitors of fatty acid amide hydrolase.
Topics: Amidohydrolases; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Imidazoles; Mice; Mice, Knockout; Morphine; Pain Measurement; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Rimonabant | 2007 |
Nummular headache: another case treated with gabapentin.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans | 2007 |
Study pharmacologic of the GABAergic and glutamatergic drugs on seizures and status epilepticus induced by pilocarpine in adult Wistar rats.
Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Ketamine; Male; Muscarinic Agonists; N-Methylaspartate; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Receptors, GABA; Receptors, Neurotransmitter; Seizures; Status Epilepticus; Vigabatrin | 2007 |
Prolonged myotonia and dystonia after general anaesthesia in a patient taking gabapentin.
Topics: Amines; Analgesics; Anesthetics, General; Cyclohexanecarboxylic Acids; Drug Interactions; Dystonia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Myotonia; Postoperative Complications | 2007 |
Validated HPLC method for the determination of gabapentin in human plasma using pre-column derivatization with 1-fluoro-2,4-dinitrobenzene and its application to a pharmacokinetic study.
Topics: Adult; Amines; Calibration; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dinitrofluorobenzene; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2007 |
Oral gabapentin activates spinal cholinergic circuits to reduce hypersensitivity after peripheral nerve injury and interacts synergistically with oral donepezil.
Topics: Administration, Oral; Amines; Analgesics; Animals; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Donepezil; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Indans; Injections, Spinal; Male; Pain; Peripheral Nerve Injuries; Piperidines; Rats; Rats, Sprague-Dawley; Spinal Cord | 2007 |
The antinociceptive effect of systemic gabapentin is related to the type of sensitization-induced hyperalgesia.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Pain Measurement; Rats; Rats, Wistar; Spinal Cord | 2007 |
The effect of the palmitoylethanolamide analogue, palmitoylallylamide (L-29) on pain behaviour in rodent models of neuropathy.
Topics: Amides; Amines; Animals; Behavior, Animal; Camphanes; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Endocannabinoids; Ethanolamines; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Indoles; Injections, Intraperitoneal; Male; Pain; Pain Measurement; Pain Threshold; Palmitic Acids; Physical Stimulation; Piperidines; PPAR alpha; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Sciatic Neuropathy; Temperature; Zalcitabine | 2007 |
Combination therapy reduces self-injurious behavior in a chimpanzee (Pan Troglodytes Troglodytes): a case report.
Topics: Amines; Animals; Anti-Anxiety Agents; Ape Diseases; Behavior Therapy; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Pan troglodytes; Self-Injurious Behavior | 2007 |
Gabapentin-induced severe myopathy.
Topics: Aged, 80 and over; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Muscular Diseases; Rhabdomyolysis | 2007 |
Single-dose gabapentin does not augment postoperative analgesia in ambulatory arthroscopic shoulder surgery.
Topics: Adjuvants, Anesthesia; Ambulatory Surgical Procedures; Amines; Arthroscopy; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Shoulder | 2007 |
Sciatic neuropathy after lower-extremity trauma: successful treatment of an uncommon pain and disability syndrome in an adolescent.
Topics: Accidents, Traffic; Adolescent; Amines; Analgesics; Bicycling; Causalgia; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain Measurement; Physical Therapy Modalities; Range of Motion, Articular; Sciatic Nerve; Sciatic Neuropathy | 2007 |
Clinical update: new treatments for hot flushes.
Topics: Amines; Cyclohexanecarboxylic Acids; Estradiol; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Isoflavones; Male; Middle Aged; Progestins; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors | 2007 |
Defensive-like behaviors induced by ultrasound: further pharmacological characterization in Lister-hooded rats.
Topics: Amines; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Bridged Bicyclo Compounds; Buspirone; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Diazepam; Dose-Response Relationship, Drug; Escape Reaction; Fear; Freezing Reaction, Cataleptic; Gabapentin; gamma-Aminobutyric Acid; Haloperidol; Imidazoles; Male; Morphine; Motor Activity; Nociceptin Receptor; Pregabalin; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, Opioid; Spiro Compounds; Thiazoles; Ultrasonics | 2007 |
Effects of genetic variation in the novel organic cation transporter, OCTN1, on the renal clearance of gabapentin.
Topics: Adolescent; Adult; Amines; Cell Line; Cohort Studies; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Genetic Variation; Glomerular Filtration Rate; Humans; Kidney Tubules; Leucine; Male; Metabolic Clearance Rate; Organic Cation Transporter 1; Phenylalanine; Polymorphism, Genetic; Reference Values | 2008 |
Transverse myelitis caused by varicella zoster: case reports.
Topics: Acute Disease; Amines; Amitriptyline; Analgesics, Non-Narcotic; Chickenpox; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Herpesvirus 3, Human; Humans; Methylprednisolone; Middle Aged; Myelitis, Transverse | 2007 |
Paroxysmal autonomic instability with dystonia.
Topics: Adult; Amines; Autonomic Nervous System Diseases; Benzodiazepines; Brain Injuries; Cyclohexanecarboxylic Acids; Dystonia; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Syndrome | 2007 |
Career lifetime advances and key developments: diabetes.
Topics: Amines; Amitriptyline; Analgesics; Antidepressive Agents; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Thiophenes | 2007 |
Life-threatening status epilepticus following gabapentin administration in a patient with benign adult familial myoclonic epilepsy.
Topics: Acute Disease; Amines; Anticonvulsants; Benzodiazepines; Cyclohexanecarboxylic Acids; Drug Resistance; Electroencephalography; Epilepsies, Myoclonic; Gabapentin; gamma-Aminobutyric Acid; Haplotypes; Humans; Male; Middle Aged; Pedigree; Severity of Illness Index; Status Epilepticus; Thiopental; Tremor | 2007 |
Chronic orchialgia: consider gabapentin or nortriptyline before considering surgery.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Amines; Calcium Channel Blockers; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nortriptyline; Pain; Testicular Diseases | 2007 |
[Gabapentin in the treatment of SUNCT syndrome].
Topics: Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; SUNCT Syndrome; Treatment Outcome | 2007 |
[The 10-minute-consultation: chronic singultus].
Topics: Aged; Amines; Anti-Ulcer Agents; Anticonvulsants; Chronic Disease; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Male; Omeprazole; Pregabalin; Recurrence | 2007 |
[Gabapentin mitigates neuropathic pain in cancer patients--a case report].
Topics: Adenocarcinoma; Amines; Analgesics; Bone Neoplasms; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neuralgia; Pain, Intractable; Rectal Neoplasms; Sacrum | 2007 |
Migraine secondary to superior oblique myokymia.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Migraine Disorders; Trochlear Nerve Diseases | 2007 |
Gabapentin action and interaction on the antinociceptive effect of morphine on visceral pain in mice.
Topics: Acetic Acid; Amines; Analgesics; Analgesics, Opioid; Analysis of Variance; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Sodium Chloride | 2008 |
Transient allodynia pain models in mice for early assessment of analgesic activity.
Topics: Adrenergic alpha-Antagonists; Amines; Amitriptyline; Analgesics; Animals; Clonidine; Cyclohexanecarboxylic Acids; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Memantine; Mice; Mice, Inbred C57BL; Morphine; N-Methylaspartate; Pain; Peripheral Nervous System; Phenylephrine; Piperazines; Prostaglandin Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, N-Methyl-D-Aspartate; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Reproducibility of Results; Spinal Cord; Spinal Nerves; Time Factors | 2008 |
Divalproex, lithium and suicide among Medicaid patients with bipolar disorder.
Topics: Adult; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Emergency Services, Psychiatric; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lithium Compounds; Male; Medicaid; Oregon; Proportional Hazards Models; Psychotropic Drugs; Risk Factors; Suicide; Suicide Prevention; Suicide, Attempted; United States; Valproic Acid | 2008 |
Influence of aminophylline on the anticonvulsive action of gabapentin in the mouse maximal electroshock seizure threshold model.
Topics: Amines; Aminophylline; Animals; Anticonvulsants; Brain; Brain Chemistry; Bronchodilator Agents; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Interactions; Electroshock; Gabapentin; gamma-Aminobutyric Acid; Immunoassay; Male; Mice; Psychomotor Performance; Seizures; Time | 2007 |
Gabapentin for the treatment of neuropathic pain in a pregnant horse.
Topics: Amines; Analgesics; Animals; Colic; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Horses; Neuralgia; Pain Measurement; Postoperative Complications; Pregnancy; Safety; Treatment Outcome | 2007 |
Cost-effectiveness of a lidocaine 5% medicated plaster relative to gabapentin for postherpetic neuralgia in the United Kingdom.
Topics: Administration, Cutaneous; Aged; Amines; Analgesics; Anesthetics, Local; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Markov Chains; Models, Econometric; Neuralgia, Postherpetic; Quality-Adjusted Life Years | 2007 |
Whole-body tremulousness: isolated generalized polymyoclonus.
Topics: Adult; Aged; Amines; Anticonvulsants; Autoimmunity; Breast Neoplasms; Clonazepam; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Electromyography; Excitatory Amino Acid Antagonists; Female; Gabapentin; Gait Disorders, Neurologic; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Myoclonus; Selective Serotonin Reuptake Inhibitors; Tremor | 2007 |
Long-term effect of gabapentin in stiff limb syndrome: a case report.
Topics: Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Stiff-Person Syndrome; Time | 2007 |
Gabapentin completely attenuated the acute morphine induced c-Fos expression in the rat striatum.
Topics: Amines; Analgesics; Analgesics, Opioid; Animals; Corpus Striatum; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Morphine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 2007 |
Effect of gabapentin on c-Fos expression in the CNS after paw surgery in rats.
Topics: Amines; Analgesics; Animals; Brain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation; Genes, fos; Hindlimb; Kinetics; Male; Neurons; Pain, Postoperative; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 2007 |
Status epilepticus secondary to hypertensive encephalopathy as the presenting manifestation of Guillain-Barré syndrome.
Topics: Adolescent; Amines; Anticonvulsants; Antihypertensive Agents; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Electroencephalography; Female; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Humans; Hypertensive Encephalopathy; Immunoglobulins; Labetalol; Phenytoin; Spinal Puncture; Status Epilepticus; Tomography, X-Ray Computed | 2007 |
Inhibitory mechanisms of gabapentin, an antiseizure drug, on platelet aggregation.
Topics: Amines; Anticonvulsants; Calcium; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Flow Cytometry; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunoblotting; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositols; Phosphorylation; Platelet Aggregation; Thromboxane A2; Type C Phospholipases | 2007 |
Prescribing patterns of antiepileptic drugs in Italy: a nationwide population-based study in the years 2000-2005.
Topics: Adolescent; Adult; Age Distribution; Aged; Amines; Anticonvulsants; Carbamazepine; Catchment Area, Health; Cohort Studies; Cyclohexanecarboxylic Acids; Drug Prescriptions; Drug Utilization; Epilepsy; Family Practice; Female; Gabapentin; gamma-Aminobutyric Acid; Geography; Humans; Italy; Longitudinal Studies; Male; Middle Aged; Mood Disorders; Pain; Pharmacoepidemiology; Phenobarbital; Practice Patterns, Physicians'; Prevalence; Valproic Acid | 2007 |
Piezoelectric pumping in flow analysis: Application to the spectrophotometric determination of gabapentin.
Topics: Amines; Cyclohexanecarboxylic Acids; Electronics; Flow Injection Analysis; Gabapentin; gamma-Aminobutyric Acid; Pharmaceutical Preparations; Spectrophotometry | 2007 |
Acupuncture, ketamine and piriformis syndrome--a case report from palliative care.
Topics: Acupuncture Therapy; Amines; Analgesics; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hodgkin Disease; Humans; Ketamine; Male; Middle Aged; Muscular Diseases; Pain; Pain Management; Palliative Care; Spinal Stenosis; Syndrome; Treatment Outcome | 2007 |
Open-label study of a proprietary treatment program targeting type A gamma-aminobutyric acid receptor dysregulation in methamphetamine dependence.
Topics: Adolescent; Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Female; Flumazenil; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydroxyzine; Male; Methamphetamine; Middle Aged; Patient Dropouts; Prospective Studies; Receptors, GABA; Substance-Related Disorders | 2007 |
Optimization of an HPLC method for determination of gabapentin in dosage forms through derivatization with 1-fluoro-2,4-dinitrobenzene.
Topics: Amines; Anticonvulsants; Calibration; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dinitrofluorobenzene; Dosage Forms; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2007 |
A retrospective evaluation of the use of gabapentin and pregabalin in patients with postherpetic neuralgia in usual-care settings.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Amines; Analgesics; Analgesics, Opioid; Anticonvulsants; Cyclohexanecarboxylic Acids; Databases as Topic; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Male; Middle Aged; Neuralgia, Postherpetic; Pain Measurement; Practice Patterns, Physicians'; Pregabalin; Retrospective Studies; Tramadol; Treatment Outcome; United States | 2007 |
Comparison of the stability of split and intact gabapentin tablets.
Topics: Amines; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Solubility; Tablets | 2008 |
Development and application of a validated HPLC method for the analysis of dissolution samples of gabapentin drug products.
Topics: Acetonitriles; Amines; Anticonvulsants; Calibration; Capsules; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Contamination; Drug Stability; Furans; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Lactams; Linear Models; Methanol; Molecular Structure; Reproducibility of Results; Solubility; Spectrophotometry, Ultraviolet; Spiro Compounds; Tablets; Technology, Pharmaceutical; Time Factors | 2008 |
Chorea as a side effect of gabapentin (Neurontin) in a patient with complex regional pain syndrome Type 1.
Topics: Amines; Analgesics; Chorea; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged | 2008 |
Case reports: zoster pain in haematological malignancies: effective pain relief with oxycodone in patients unresponsive to other analgesic measures.
Topics: Acute Disease; Aged; Aged, 80 and over; Amines; Analgesics; Antiviral Agents; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Hematologic Neoplasms; Herpes Zoster; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Oxycodone; Pain; Treatment Outcome | 2007 |
Case reports: red scrotal syndrome: a localized phenotypical expression of erythromelalgia.
Topics: Administration, Oral; Amines; Analgesics; Cyclohexanecarboxylic Acids; Erythromelalgia; Gabapentin; gamma-Aminobutyric Acid; Genital Diseases, Male; Humans; Male; Middle Aged; Scrotum; Syndrome; Treatment Outcome | 2007 |
Gabapentin treatment for notalgia paresthetica, a common isolated peripheral sensory neuropathy.
Topics: Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Paresthesia; Peripheral Nervous System Diseases; Pruritus; Sensation Disorders | 2007 |
Gabapentin suppresses spasticity in the spinal cord-injured rat.
Topics: Amines; Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Cross-Over Studies; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electromyography; Female; Gabapentin; gamma-Aminobutyric Acid; Muscle Spasticity; Rats; Rats, Sprague-Dawley; Reflex, Abnormal; Spinal Cord Injuries; Time Factors | 2007 |
[Should we care about pregabalin for elderly patients with a history of cardiac dysrhythmia?].
Topics: Aged, 80 and over; Amines; Analgesics; Atrial Fibrillation; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Failure; Herpes Zoster; Humans; Neuritis; Pregabalin; Tachycardia, Paroxysmal | 2008 |
Felbamate but not phenytoin or gabapentin reduces glutamate release by blocking presynaptic NMDA receptors in the entorhinal cortex.
Topics: 2-Amino-5-phosphonovalerate; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Patch-Clamp Techniques; Phenylcarbamates; Phenytoin; Propylene Glycols; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic | 2007 |
Gestational trophoblastic disease with painful skin metastases.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Fatal Outcome; Female; Gabapentin; gamma-Aminobutyric Acid; Gestational Trophoblastic Disease; Humans; Pain; Pregnancy; Skin Neoplasms | 2008 |
Evaluation of ketamine, nimodipine, gabapentin and imipramine in partial sciatic nerve transection model of neuropathic pain in rat: an experimental study.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Imipramine; Ketamine; Male; Nimodipine; Rats; Rats, Wistar; Sciatic Nerve; Sciatic Neuropathy | 2007 |
Possible involvement of GABAergic modulation in the protective effect of gabapentin against immobilization stress-induced behavior alterations and oxidative damage in mice.
Topics: Amines; Animals; Behavior, Animal; Catalase; Cyclohexanecarboxylic Acids; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Glutathione; Immobilization; Mice; Motor Activity; Muscimol; Oxidation-Reduction; Picrotoxin; Stress, Psychological | 2007 |
The effects of medical treatment and rehabilitation in a patient with adult tethered cord syndrome in the late postoperative period.
Topics: Adult; Amines; Analgesics; Clonidine; Cyclohexanecarboxylic Acids; Exercise Therapy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Neural Tube Defects; Postoperative Period | 2007 |
Gabapentin for painful legs and moving toes syndrome.
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Leg; Pain; Syndrome; Toes | 2007 |
The effect of gabapentin and phenytoin on sperm-morphology in Wistar rats.
Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Cyclophosphamide; Gabapentin; gamma-Aminobutyric Acid; Male; Mutagens; Phenytoin; Rats; Rats, Wistar; Spermatozoa | 2007 |
Effects of gabapentin on cocaine self-administration, cocaine-triggered relapse and cocaine-enhanced nucleus accumbens dopamine in rats.
Topics: Amines; Animals; Anti-Anxiety Agents; Cocaine; Cocaine-Related Disorders; Cyclohexanecarboxylic Acids; Disruptive, Impulse Control, and Conduct Disorders; Dopamine; Gabapentin; gamma-Aminobutyric Acid; Male; Nucleus Accumbens; Rats; Rats, Long-Evans; Recurrence; Self Administration; Vasoconstrictor Agents | 2008 |
Erythromelalgia in a diabetic patient managed with gabapentin.
Topics: Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetes Complications; Diabetes Mellitus; Drug Therapy, Combination; Erythromelalgia; Female; Gabapentin; gamma-Aminobutyric Acid; Gliclazide; Humans; Hypoglycemic Agents; Metformin | 2008 |
Role of Stellate ganglion block in post CABG sympathetically mediated chest pain.
Topics: Acute Disease; Amines; Antidepressive Agents, Tricyclic; Chest Pain; Coronary Artery Bypass; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Morphine; Nerve Block; Stellate Ganglion; Sympathetic Nervous System; Time Factors | 2007 |
Differential modulation of K(+)-evoked (3)H-neurotransmitter release from human neocortex by gabapentin and pregabalin.
Topics: Acetylcholine; Adolescent; Adult; Aged; Amines; Analgesics; Anticonvulsants; Calcium Channels; Child; Cyclohexanecarboxylic Acids; Dopamine; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Isoleucine; Ligands; Male; Middle Aged; Neocortex; Norepinephrine; Potassium; Pregabalin; Serotonin; Stereoisomerism | 2008 |
A case report on idiopathic recurrent priapism.
Topics: Adult; Amines; Androgen Antagonists; Baclofen; Cyclohexanecarboxylic Acids; Cyproterone Acetate; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Muscle Relaxants, Central; Priapism; Secondary Prevention | 2007 |
Gabapentin for decerebrate rigidity: a case report.
Topics: Amines; Anticonvulsants; Cerebral Hemorrhage; Cyclohexanecarboxylic Acids; Decerebrate State; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intubation, Gastrointestinal; Middle Aged; Pons; Time Factors; Transcranial Magnetic Stimulation; Treatment Outcome; Unconsciousness | 2008 |
Benign fasciculations responsive to gabapentin.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fasciculation; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged | 2007 |
Cost effectiveness of duloxetine in the treatment of diabetic peripheral neuropathic pain in the UK.
Topics: Amines; Amitriptyline; Antidepressive Agents; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Econometric; Paclitaxel; Pain Measurement; Prospective Studies; Quality-Adjusted Life Years; Sickness Impact Profile; Thiophenes; Treatment Outcome; United Kingdom | 2008 |
Mechanisms of potassium- and capsaicin-induced axonal calcitonin gene-related peptide release: involvement of L- and T-type calcium channels and TRPV1 but not sodium channels.
Topics: Amines; Animals; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Capsaicin; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Extracellular Fluid; Gabapentin; gamma-Aminobutyric Acid; Immunoenzyme Techniques; In Vitro Techniques; Male; Potassium; Rats; Sciatic Nerve; Sodium Channel Blockers; Sodium Channels; Statistics, Nonparametric; TRPV Cation Channels | 2008 |
Gabapentin produces PKA-dependent pre-synaptic inhibition of GABAergic synaptic transmission in LC neurons following partial nerve injury in mice.
Topics: Amines; Animals; Cyclic AMP-Dependent Protein Kinases; Cyclohexanecarboxylic Acids; Efferent Pathways; Enzyme Activation; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Ligation; Locus Coeruleus; Male; Mice; Neural Inhibition; Nociceptors; Organ Culture Techniques; Pain; Patch-Clamp Techniques; Peripheral Nervous System Diseases; Posterior Horn Cells; Presynaptic Terminals; Receptors, GABA-A; Sciatic Neuropathy; Synaptic Transmission | 2008 |
Gabapentin and sexual dysfunction: report of two cases.
Topics: Adolescent; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Libido; Male; Middle Aged; Neuralgia; Nitric Oxide; Peripheral Nerves; Peripheral Nervous System Diseases; Sexual Dysfunction, Physiological; Sexual Dysfunctions, Psychological; Up-Regulation; Vasoactive Intestinal Peptide; Weight Gain; Withholding Treatment | 2008 |
Teratogenic effects of the anticonvulsant gabapentin in mice.
Topics: Abnormalities, Drug-Induced; Amines; Animals; Anticonvulsants; Body Weight; Congenital Abnormalities; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Mice; Mice, Inbred ICR; Models, Chemical; Pregnancy; Pregnancy, Animal; Teratogens | 2008 |
Hemichorea associated with gabapentin therapy with hypoperfusion in contralateral basal ganglion - a case of a paraplegic patient with neuropathic pain.
Topics: Adult; Amines; Analgesics; Basal Ganglia; Cerebrovascular Circulation; Chorea; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Paraplegia; Tomography, Emission-Computed, Single-Photon | 2008 |
Regions of interest analysis in pharmacological fMRI: how do the definition criteria influence the inferred result?
Topics: Adult; Amines; Analgesics; Brain; Capsaicin; Cyclohexanecarboxylic Acids; Echo-Planar Imaging; Gabapentin; gamma-Aminobutyric Acid; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Models, Statistical; Oxygen; Pain | 2008 |
Gabapentin as a therapeutic option in uremic pruritus.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pruritus; Uremia | 2008 |
Gabapentin for ultra resistant schizophrenia with aggressive behavior.
Topics: Adult; Aggression; Amines; Anticonvulsants; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Haloperidol; Humans; Male; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; Violence | 2008 |
Gabapentin evoked changes in functional activity in nociceptive regions in the brain of the anaesthetized rat: an fMRI study.
Topics: Administration, Oral; Amines; Analgesics; Animals; Blood Pressure; Brain; Brain Mapping; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Infusions, Intravenous; Magnetic Resonance Imaging; Oxygen; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley | 2008 |
Discriminative stimulus effects of tiagabine and related GABAergic drugs in rats.
Topics: Administration, Oral; Amines; Animals; Anticonvulsants; Azabicyclo Compounds; Baclofen; Benzodiazepines; Bicuculline; Brain; Cyclohexanecarboxylic Acids; Discrimination Learning; Dose-Response Relationship, Drug; GABA Agents; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; Gabapentin; gamma-Aminobutyric Acid; Generalization, Stimulus; Hypnotics and Sedatives; Injections, Intraperitoneal; Isoxazoles; Male; Nipecotic Acids; Piperazines; Pyridines; Rats; Thiophenes; Tiagabine; Zolpidem | 2008 |
Nociceptin-receptor deficiency prevents postherpetic pain without effects on acute herpetic pain in mice.
Topics: Acute Disease; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation; Herpes Simplex; Herpesvirus 1, Human; Hyperalgesia; Mice; Mice, Inbred C57BL; Mice, Knockout; Nociceptin Receptor; Pain Measurement; Protein Precursors; Receptors, Opioid; RNA, Messenger; Spinal Cord; Time Factors | 2008 |
Experimental autoimmune prostatitis induces chronic pelvic pain.
Topics: Amines; Analgesics; Anesthetics, Local; Animals; Autoimmune Diseases; Chronic Disease; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Lidocaine; Male; Mice; Mice, Inbred NOD; Nerve Fibers; Pain Measurement; Pelvic Pain; Prostate; Prostatitis; Rats; Rats, Inbred BB; Syndrome; Time Factors; Tissue Extracts | 2008 |
Gabapentin prevents delayed and long-lasting hyperalgesia induced by fentanyl in rats.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Time | 2008 |
Gabapentin as a potential option for treatment of sciatica.
Topics: Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Sciatica | 2008 |
Recurrent postoperative CRPS I in patients with abnormal preoperative sympathetic function.
Topics: Adult; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nerve Block; Carpal Tunnel Syndrome; Celecoxib; Clonidine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hand; Humans; Laser-Doppler Flowmetry; Male; Occupational Therapy; Postoperative Complications; Preoperative Care; Prospective Studies; Pyrazoles; Recurrence; Reflex; Reflex Sympathetic Dystrophy; Regional Blood Flow; Reoperation; Sulfonamides; Sympathetic Nervous System; Vasoconstriction | 2008 |
Gabapentin toxicity: an important cause of altered consciousness in patients with uraemia.
Topics: Amines; Anticonvulsants; Consciousness Disorders; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Renal Dialysis; Uremia | 2008 |
Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin.
Topics: Amines; Animals; Biological Transport; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ligands; Mice; Protein Subunits; Rabbits; Rats | 2008 |
Cerebellar cognitive affective syndrome associated with topiramate.
Topics: Amines; Anticonvulsants; Carbamazepine; Cerebellar Diseases; Cerebellum; Cognition Disorders; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Mood Disorders; Neuropsychological Tests; Oxcarbazepine; Syndrome; Topiramate; Treatment Outcome | 2008 |
Pharmacokinetics of gabapentin in horses.
Topics: Administration, Oral; Amines; Animals; Anticonvulsants; Area Under Curve; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Horses | 2008 |
Gabapentin activates ROMK1 channels by a protein kinase A (PKA)-dependent mechanism.
Topics: Amines; Animals; Cyclic AMP-Dependent Protein Kinases; Cyclohexanecarboxylic Acids; Data Interpretation, Statistical; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Oocytes; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Potassium Channels, Inwardly Rectifying; Protein Conformation; Xenopus laevis | 2008 |
Mercury intoxication and neuropathic pain.
Topics: Adolescent; Amines; Analgesics, Opioid; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mercury Poisoning, Nervous System; Pain; Tramadol | 2008 |
Standard error of measurement as a valid alternative to minimally important difference for evaluating the magnitude of changes in patient-reported outcomes measures.
Topics: Amines; Analgesics; Cohort Studies; Cyclohexanecarboxylic Acids; Data Interpretation, Statistical; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Patient Satisfaction; Treatment Outcome | 2008 |
Occipital neuralgia with cervical myelitis.
Topics: Amines; Analgesics; Anesthetics, Local; Cervical Vertebrae; Cyclohexanecarboxylic Acids; Facial Neuralgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Male; Middle Aged; Myelitis; Occipital Lobe; Rare Diseases; Treatment Outcome | 2008 |
Polymorphs of gabapentin.
Topics: Amines; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Dimerization; Gabapentin; gamma-Aminobutyric Acid; Hydrogen Bonding; Models, Molecular; Molecular Structure; Stereoisomerism | 2008 |
New antiepileptic drugs in pediatric epilepsy.
Topics: Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Pediatrics; Phenylcarbamates; Piracetam; Practice Guidelines as Topic; Propylene Glycols; Topiramate; Triazines; Vigabatrin | 2008 |
Chronic, but not acute, tricyclic antidepressant treatment alleviates neuropathic allodynia after sciatic nerve cuffing in mice.
Topics: Amines; Amitriptyline; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain; Chronic Disease; Cyclohexanecarboxylic Acids; Denervation; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Ligation; Male; Mice; Mice, Inbred C57BL; Narcotic Antagonists; Nortriptyline; Opioid Peptides; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Receptors, Opioid; Sciatic Neuropathy | 2008 |
Successful use of gabapentin in acute pain management following burn injury: a case series.
Topics: Adult; Amines; Analgesics; Burns; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain | 2008 |
Gabapentin therapy for painful, blind glaucomatous eye: case report.
Topics: Aged; Amines; Analgesics; Blindness; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glaucoma; Humans; Male; Pain; Pain Measurement | 2008 |
[Drug-induced hypersensitivity syndrome due to gabapentin].
Topics: Amines; Aneurysm, Ruptured; Anticonvulsants; Biopsy; Cerebral Hemorrhage; Cyclohexanecarboxylic Acids; Drug Hypersensitivity; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged | 2008 |
[Efficacy of gabapentin in the treatment of carpal tunnel syndrome].
Topics: Amines; Analgesics; Carpal Tunnel Syndrome; Cyclohexanecarboxylic Acids; Electromyography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Prospective Studies | 2008 |
Gabapentin neuroprotection and seizure suppression in immature mouse brain ischemia.
Topics: Amines; Animals; Animals, Newborn; Anticonvulsants; Atrophy; Behavior, Animal; Body Temperature; Brain; Brain Ischemia; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Mice; Neuroprotective Agents; Seizures; Sex Factors | 2008 |
Chorea due to gabapentin monotherapy in a not encephalopatic patient.
Topics: Aged; Amines; Analgesics; Chorea; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging | 2008 |
Heat stress disorders and headache: a case of new daily persistent headache secondary to heat stroke.
Topics: Amines; Amitriptyline; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders; Headache Disorders, Secondary; Heat Stroke; Humans; Middle Aged | 2008 |
Fibromyalgia: understanding a mysterious ailment.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Nociceptors; Pregabalin | 2007 |
Gabapentin attenuates acute hypoxic stress-induced behavioral alterations and oxidative damage in mice: possible involvement of GABAergic mechanism.
Topics: Amines; Analysis of Variance; Animals; Brain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hypoxia; Lipid Peroxidation; Mice; Motor Activity; Muscimol; Oxidative Stress; Picrotoxin; Spectrophotometry | 2008 |
Patient compliance with neuropathic pain treatment.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Patient Compliance; Treatment Outcome | 2008 |
Gender differences in the antinociceptive effect of tramadol, alone or in combination with gabapentin, in mice.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Drug Synergism; Drug Therapy, Combination; Drug Tolerance; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Pain Measurement; Sex Characteristics; Sex Factors; Tramadol; Treatment Outcome | 2008 |
Use of propofol anesthesia and adjunctive treatment with levetiracetam and gabapentin in managing status epilepticus in a patient of acute intermittent porphyria.
Topics: Amines; Anesthetics, Intravenous; Anticonvulsants; Child; Comorbidity; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Levetiracetam; Male; Piracetam; Porphyria, Acute Intermittent; Propofol; Status Epilepticus | 2008 |
The use of gabapentin for recurrent painful attacks with multiple piloleiomyomas.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Leiomyomatosis; Male; Middle Aged; Pain; Recurrence; Skin Neoplasms | 2008 |
Pharmacological treatment of neuropathic pain in older persons.
Topics: Aged; Amines; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Osteoarthritis; Pain; Peripheral Nervous System Diseases; Practice Guidelines as Topic; Selective Serotonin Reuptake Inhibitors; Tramadol | 2008 |
Urinary and rectal incontinence during gabapentin therapy.
Topics: Aged; Amines; Anticonvulsants; Carcinoma, Non-Small-Cell Lung; Cyclohexanecarboxylic Acids; Fecal Incontinence; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lung Neoplasms; Pain; Urinary Incontinence | 2008 |
Role of gabapentin in the treatment of uremic pruritus.
Topics: Amines; Antipruritics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Diseases; Pruritus; Renal Dialysis; Uremia | 2008 |
Antinociceptive activity of the S1P-receptor agonist FTY720.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Fingolimod Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Injections, Spinal; Pain; Pain Measurement; Propylene Glycols; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sphingosine | 2008 |
The antinociceptive effects of anticonvulsants in a mouse visceral pain model.
Topics: Acetic Acid; Amines; Analgesics; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Fructose; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Pain; Pain Measurement; Rotarod Performance Test; Time Factors; Topiramate; Viscera | 2008 |
The experience of phantom limb pain in patients with combat-related traumatic amputations.
Topics: Adolescent; Adult; Amines; Amputation, Traumatic; Amputees; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Military Personnel; Outpatient Clinics, Hospital; Pain Measurement; Phantom Limb; Relaxation Therapy; Retrospective Studies; Surveys and Questionnaires; United States | 2008 |
Cellular and behavioral interactions of gabapentin with alcohol dependence.
Topics: Alcoholism; Amines; Amygdala; Animals; Behavior, Animal; Central Nervous System Depressants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Ethanol; Excitatory Amino Acid Antagonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Maze Learning; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Rats; Rats, Wistar; Self Administration; Synaptic Transmission | 2008 |
Post-traumatic short-lasting unilateral headache with cranial autonomic symptoms (SUNA).
Topics: Accidents, Traffic; Adult; Amines; Carbamazepine; Conjunctiva; Cyclohexanecarboxylic Acids; Facial Pain; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypesthesia; Male; Mandibular Fractures; Neuralgia; Post-Traumatic Headache; Postoperative Complications; Tears; Trigeminal Nerve; Whiplash Injuries | 2008 |
[Postoperative inconveniences after breast cancer surgery].
Topics: Acetaminophen; Amines; Analgesics; Antiemetics; Antitussive Agents; Breast Neoplasms; Celecoxib; Cyclohexanecarboxylic Acids; Cyclooxygenase Inhibitors; Dexamethasone; Dextromethorphan; Droperidol; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ondansetron; Pain, Postoperative; Postoperative Nausea and Vomiting; Pyrazoles; Sulfonamides | 2008 |
[Multimodal treatment of pain and nausea in breast cancer surgery].
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Antiemetics; Antitussive Agents; Breast Neoplasms; Celecoxib; Cyclohexanecarboxylic Acids; Cyclooxygenase Inhibitors; Dexamethasone; Dextromethorphan; Droperidol; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Ondansetron; Pain, Postoperative; Postoperative Nausea and Vomiting; Prospective Studies; Pyrazoles; Sulfonamides | 2008 |
Gabapentin for breakthrough pain due to bone metastases.
Topics: Amines; Analgesics; Bone Neoplasms; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Pain Measurement; Treatment Outcome | 2008 |
The trigeminal trophic syndrome: an unusual cause of face pain, dysaesthesias, anaesthesia and skin/soft tissue lesions.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Child; Cyclohexanecarboxylic Acids; Erythema; Face; Facial Dermatoses; Facial Pain; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypesthesia; Iatrogenic Disease; Male; Massage; Middle Aged; Paresthesia; Postoperative Complications; Skin Ulcer; Syndrome; Trigeminal Nerve Injuries; Trigeminal Neuralgia; Trigeminal Nuclei | 2008 |
Anxiety-like behaviour in rats with mononeuropathy is reduced by the analgesic drugs morphine and gabapentin.
Topics: Amines; Analgesics; Animals; Anxiety; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mononeuropathies; Morphine; Neuralgia; Pain Measurement; Rats; Rats, Wistar | 2008 |
Post-thoracotomy shoulder pain and gabapentin: a tale of two enigmas.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Shoulder Pain; Thoracic Surgery, Video-Assisted; Thoracotomy | 2008 |
Defining neuralgiform headache with ipsilateral autonomic symptoms: case report in a headache center.
Topics: Aged; Amines; Analgesics, Opioid; Anticonvulsants; Autonomic Nervous System; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Ketorolac; Male; Pregabalin; Tramadol; Trigeminal Neuralgia | 2008 |
Antinociceptive action of GLYX-13: an N-methyl-D-aspartate receptor glycine site partial agonist.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Time Factors | 2008 |
Alternative splicing of the Ca2+ channel beta4 subunit confers specificity for gabapentin inhibition of Cav2.1 trafficking.
Topics: Alanine; Alternative Splicing; Amines; Animals; Arginine; Calcium Channels; Calcium Channels, N-Type; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Models, Biological; Mutation; Protein Isoforms; Protein Subunits; Protein Transport; Rabbits; Xenopus | 2008 |
In vitro/in vivo characterization of melt-molded gabapentin-loaded poly(epsilon-caprolactone) implants for sustained release in animal studies.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Polyesters; Solubility; Technology, Pharmaceutical | 2008 |
Pregabalin and gabapentin inhibit substance P-induced NF-kappaB activation in neuroblastoma and glioma cells.
Topics: Amines; Animals; Cell Line, Tumor; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Glioma; Humans; Inflammation; Neuroblastoma; NF-kappa B; Pregabalin; Rats; Rats, Sprague-Dawley; Signal Transduction; Substance P | 2008 |
Gabapentin and tinnitus relief.
Topics: Amines; Anticonvulsants; Brain; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Receptors, GABA-A; Selection Bias; Tinnitus; Treatment Outcome | 2008 |
Retention rates of new antiepileptic drugs in localization-related epilepsy: a single-center study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy; Female; Finland; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Levetiracetam; Licensure, Pharmacy; Male; Middle Aged; Nipecotic Acids; Piracetam; Retrospective Studies; Tiagabine; Topiramate; Treatment Outcome; Triazines; Young Adult | 2009 |
Intrathecal clonidine suppresses phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit in spinal dorsal horn neurons of rats with neuropathic pain.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amines; Analgesics; Animals; Anticonvulsants; Clonidine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Gabapentin; gamma-Aminobutyric Acid; Idazoxan; Neuralgia; Phosphorylation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Spinal Cord | 2008 |
Gabapentin for the treatment of glossodynia due to an unusual cause.
Topics: Adult; Amines; Analgesics; Areca; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glossalgia; Habits; Humans; Male | 2008 |
One from column A and one from column B: may I take your order?
Topics: Amines; Analgesics, Opioid; Anti-Arrhythmia Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Mexiletine; Morphine; Pain, Postoperative; Phantom Limb; Randomized Controlled Trials as Topic | 2008 |
Cost-effectiveness analysis of a lidocaine 5% medicated plaster compared with gabapentin and pregabalin for treating postherpetic neuralgia: a german perspective.
Topics: Administration, Cutaneous; Amines; Analgesics; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Delphi Technique; Drug Costs; Endpoint Determination; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Germany; Lidocaine; Markov Chains; Models, Economic; Models, Statistical; National Health Programs; Neuralgia, Postherpetic; Pain Measurement; Pregabalin; Quality-Adjusted Life Years | 2008 |
Challenges of fragmented care in long-term management of pelvic pain.
Topics: Acetaminophen; Adult; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Anxiety Agents; Chronic Disease; Continuity of Patient Care; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Drug Therapy, Combination; Endometriosis; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocodone; Hypoglycemic Agents; Interdisciplinary Communication; Pelvic Pain; Risk Factors; Rosiglitazone; Substance-Related Disorders; Thiazolidinediones; Trazodone; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms | 2007 |
Tramadol-induced seizurogenic effect: a possible role of opioid-dependent gamma-aminobutyric acid inhibitory pathway.
Topics: Amines; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Mice; Mice, Inbred Strains; Naloxone; Narcotic Antagonists; Pentylenetetrazole; Receptors, GABA; Receptors, Opioid; Seizures; Tramadol | 2008 |
Inhibition of osteosarcoma-induced thermal hyperalgesia in mice by the orally active dual enkephalinase inhibitor PL37. Potentiation by gabapentin.
Topics: Administration, Oral; Amines; Analgesics; Animals; Bone Neoplasms; Cyclohexanecarboxylic Acids; Disulfides; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Mice; Naloxone; Neprilysin; Osteosarcoma; Propylamines; Quaternary Ammonium Compounds; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2008 |
Gabapentin-Induced myoclonus: case report.
Topics: Aged, 80 and over; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Myoclonus; Parkinson Disease | 2008 |
In Vitro/in vivo relationship of gabapentin from a sustained-release tablet formulation: a pharmacokinetic study in the beagle dog.
Topics: Amines; Animals; Anticonvulsants; Area Under Curve; Calibration; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Dogs; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Male; Quality Control; Reproducibility of Results; Solubility | 2008 |
Gabapentin for refractory idiopathic trigeminal neuralgia.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain Measurement; Trigeminal Neuralgia | 2008 |
Isobolographic and behavioral characterizations of interactions between vigabatrin and gabapentin in two experimental models of epilepsy.
Topics: Amines; Animals; Anticonvulsants; Behavior, Animal; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Muscle Strength; Pentylenetetrazole; Psychomotor Performance; Seizures; Vigabatrin | 2008 |
Combined preoperative use of celecoxib and gabapentin in the management of postoperative pain.
Topics: Administration, Oral; Adult; Amines; Analgesics, Opioid; Breast Implantation; Celecoxib; Cohort Studies; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Preoperative Care; Pyrazoles; Retrospective Studies; Sulfonamides; Treatment Outcome; Young Adult | 2009 |
Treatment of neuropathic pain due to sciatic nerve injury following intramuscular injection with gabapentin in a child.
Topics: Amines; Child; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intramuscular; Male; Sciatic Nerve; Sciatic Neuropathy; Treatment Outcome; Wounds, Stab | 2008 |
Gabapentin toxicity in renal failure: the importance of dose adjustment.
Topics: Acute Kidney Injury; Aged; Amines; Animals; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Iatrogenic Disease; Pain | 2009 |
The interaction of gabapentin and N6-(2-phenylisopropyl)-adenosine R-(-)isomer (R-PIA) on mechanical allodynia in rats with a spinal nerve ligation.
Topics: Adenosine; Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Ligation; Male; Pain; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Spinal Nerves; Xanthines | 2008 |
FK1706, a novel non-immunosuppressive immunophilin ligand, modifies the course of painful diabetic neuropathy.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Immunohistochemistry; Immunophilins; Ligands; Male; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Tacrolimus | 2008 |
Retention of new AEDs in institutionalized intellectually disabled patients with epilepsy.
Topics: Adolescent; Adult; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Utilization Review; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Institutionalization; Intellectual Disability; Lamotrigine; Levetiracetam; Middle Aged; Piracetam; Retrospective Studies; Topiramate; Triazines | 2009 |
[Pain therapy after spinal surgery].
Topics: Adrenal Cortex Hormones; Amines; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bone Transplantation; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Preoperative Care; Spinal Cord Compression; Spinal Fusion | 2008 |
Synergistic interaction of gabapentin with tiagabine in the formalin test in mice: an isobolographic analysis.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Formaldehyde; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Nipecotic Acids; Pain Measurement; Psychomotor Performance; Tiagabine | 2009 |
The effect of amitriptyline, gabapentin, and carbamazepine on morphine-induced hypercarbia in rabbits.
Topics: Amines; Amitriptyline; Analgesics, Opioid; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Hypercapnia; Male; Morphine; Rabbits; Respiratory Insufficiency | 2008 |
Successful treatment of hallucinations associated with sensory impairment using gabapentin.
Topics: Aged, 80 and over; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hallucinations; Humans; Middle Aged; Sensation Disorders | 2008 |
Miller-Fisher syndrome in a patient with rheumatoid arthritis treated with adalimumab.
Topics: Adalimumab; Aged; Amines; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Humans; Miller Fisher Syndrome; Treatment Outcome; Tumor Necrosis Factor-alpha | 2009 |
Multiplicative interactions to enhance gabapentin to treat neuropathic pain.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Donepezil; Dose-Response Relationship, Drug; Drug Interactions; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Indans; Injections, Spinal; Ligation; Male; Neurotransmitter Uptake Inhibitors; Nootropic Agents; Pain; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Piperidines; Postural Balance; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Spinal Nerves; Thiophenes | 2008 |
Is there a role for anticonvulsants in the management of rheumatic pain?
Topics: Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Nervous System Diseases; Pain; Pregabalin; Rheumatic Diseases; Rheumatology | 2008 |
A probable case of gabapentin-related reversible hearing loss in a patient with acute renal failure.
Topics: Acute Kidney Injury; Amines; Anticonvulsants; Anuria; Comorbidity; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Hearing Loss; Humans; Middle Aged; Myoclonus; Renal Dialysis | 2008 |
Deep venous thrombosis and inferior vena cava agenesis causing double crush sciatic neuropathy in Behçet's disease.
Topics: Adolescent; Amines; Behcet Syndrome; Colchicine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Heparin; Humans; Injections, Intravenous; Interferons; Male; Nerve Compression Syndromes; Physical Therapy Modalities; Sciatic Nerve; Sciatica; Vena Cava, Inferior; Venous Thrombosis; Warfarin | 2008 |
[Paroxysmal kinesigenic dyskinesia: a channelopathy? Study of 19 cases].
Topics: Adolescent; Adult; Age of Onset; Amines; Anticonvulsants; Channelopathies; Child; Child, Preschool; Chorea; Chromosome Mapping; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Male; Movement Disorders; Seizures; Sex Ratio; Young Adult | 2009 |
Anxiety-like behaviour is attenuated by gabapentin, morphine and diazepam in a rodent model of HIV anti-retroviral-associated neuropathic pain.
Topics: Amines; Analgesics; Animal Diseases; Animals; Anxiety; Behavior, Animal; Cyclohexanecarboxylic Acids; Diazepam; Exploratory Behavior; Gabapentin; gamma-Aminobutyric Acid; HIV Infections; Locomotion; Male; Morphine; Neuralgia; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Reaction Time; Time Factors | 2008 |
Drug use in porphyria: a therapeutic dilemma.
Topics: Abdominal Pain; Adult; Amines; Anticonvulsants; Antiemetics; Antihypertensive Agents; Chest Pain; Cyclohexanecarboxylic Acids; Diazepam; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenytoin; Porphyria, Acute Intermittent; Promethazine; Propranolol; Vomiting | 2008 |
Differential analgesic effects of morphine and gabapentin on behavioural measures of pain and disability in a model of osteoarthritis pain in rats.
Topics: Amines; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Cold Temperature; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Iodoacetates; Locomotion; Male; Morphine; Movement; Osteoarthritis; Pain; Pain Measurement; Physical Stimulation; Postural Balance; Rats; Rats, Sprague-Dawley; Sleep | 2009 |
Improvement in psoriasis following treatment with gabapentin and pregabalin.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pregabalin; Psoriasis; Treatment Outcome | 2008 |
Gabapentin reverses microglial activation in the spinal cord of streptozotocin-induced diabetic rats.
Topics: Amines; Analgesics; Animals; Astrocytes; Cell Count; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Immunohistochemistry; Male; Microglia; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Wistar; Spinal Cord | 2009 |
Prolonged gabapentin analgesia in an experimental mouse model of fibromyalgia.
Topics: Amines; Analgesia; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Administration Routes; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Mice; Sex Factors; Time Factors | 2008 |
Effects of gabapentin and pregabalin on K+-evoked 3H-GABA and 3H-glutamate release from human neocortical synaptosomes.
Topics: Adolescent; Adult; Aged; Amines; Amino Acids, Cyclic; Anticonvulsants; Aspartic Acid; Calcium Channel Blockers; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Exocytosis; Female; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Infant; Isoleucine; Male; Middle Aged; Neocortex; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Oximes; Potassium; Pregabalin; Synaptosomes; Tacrolimus; Young Adult | 2009 |
Oxadiazolone bioisosteres of pregabalin and gabapentin.
Topics: Amines; Animals; Brain; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Octamer Transcription Factors; Organic Anion Transporters; Osteoarthritis; Oxadiazoles; Pregabalin; Rats | 2009 |
A cost-utility comparison of four first-line medications in painful diabetic neuropathy.
Topics: Amines; Analgesics; Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Desipramine; Diabetic Neuropathies; Duloxetine Hydrochloride; Economics, Pharmaceutical; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pregabalin; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Thiophenes | 2008 |
Crystal structures of a new polymorphic form of gabapentin monohydrate and the e and z isomers of 4-tertiarybutylgabapentin.
Topics: Amines; Anticonvulsants; Crystallization; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen Bonding; Isomerism; Models, Molecular; Molecular Structure | 2009 |
[Gabapentin for neurophatic pain in children: a case report].
Topics: Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Mercury Poisoning; Neuralgia | 2008 |
Gabapentin acts within the locus coeruleus to alleviate neuropathic pain.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Locus Coeruleus; Male; Neuralgia; Norepinephrine; Rats; Rats, Sprague-Dawley | 2008 |
Patterns of prescribing antiepileptic drugs for bipolar disorder.
Topics: Adult; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Drug-Related Side Effects and Adverse Reactions; Evidence-Based Medicine; Female; Gabapentin; gamma-Aminobutyric Acid; Health Knowledge, Attitudes, Practice; Humans; Information Dissemination; Male; Middle Aged; Practice Patterns, Physicians'; Psychiatry; Teaching Materials; United States | 2008 |
Disseminating findings from a drug class review: using best practices to inform prescription of antiepileptic drugs for bipolar disorder.
Topics: Advertising; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Information Dissemination; Models, Organizational; Review Literature as Topic; Social Marketing; United States | 2008 |
Gabapentin and post-thoracotomy shoulder pain.
Topics: Amines; Analgesics; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Pregabalin; Shoulder Pain; Thoracotomy | 2008 |
[Restless legs syndrome in the elderly: an unrecognized disorder].
Topics: Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Benzodiazepines; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dopamine Agents; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Narcotics; Quality of Life; Restless Legs Syndrome; Sleep Wake Disorders; Tranquilizing Agents | 2008 |
Gabapentin monotherapy for the treatment of chemotherapy-induced neuropathic pain: a pilot study.
Topics: Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug-Related Side Effects and Adverse Reactions; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Treatment Outcome; Young Adult | 2008 |
Simultaneous determination of three anticonvulsants using hydrophilic interaction LC-MS.
Topics: Amines; Anticonvulsants; Calibration; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Pregabalin; Solutions; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Temperature; Vigabatrin; Water | 2009 |
Neuropathic pain in children after exposure to mercury.
Topics: Amines; Analgesics, Non-Narcotic; Burning Mouth Syndrome; Child; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Mercury Poisoning, Nervous System; Pain; Peripheral Nervous System Diseases | 2008 |
A population pharmacokinetic model of gabapentin developed in nonparametric adaptive grid and nonlinear mixed effects modeling.
Topics: Adult; Aged; Algorithms; Amines; Area Under Curve; Bayes Theorem; Biological Availability; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Monitoring; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nonlinear Dynamics; Pain; Peripheral Nervous System Diseases; Population; Software; Statistics, Nonparametric; Young Adult | 2009 |
Beta2-adrenoceptors are essential for desipramine, venlafaxine or reboxetine action in neuropathic pain.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amines; Animals; Anticonvulsants; Antidepressive Agents; Cyclohexanecarboxylic Acids; Cyclohexanols; Desipramine; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Mice, Transgenic; Morpholines; Pain; Pain Threshold; Propanolamines; Reboxetine; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-2; Sciatic Nerve; Venlafaxine Hydrochloride; Yohimbine | 2009 |
Dixon and massey's method: the starting dose.
Topics: Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Lumbar Vertebrae; Morphine; Pain Measurement; Pain, Postoperative; Spinal Fusion | 2009 |
Peripheral neuropathy in an adolescent treated with linezolid.
Topics: Acetamides; Amines; Analgesics; Anti-Bacterial Agents; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Linezolid; Osteomyelitis; Oxazolidinones; Peripheral Nervous System Diseases | 2009 |
Bilateral ballism induced by gabapentin in idiopatic Parkinson's disease.
Topics: Aged, 80 and over; Amines; Anticonvulsants; Back Pain; Comorbidity; Cyclohexanecarboxylic Acids; Dyskinesias; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Parkinson Disease | 2009 |
The Neurontin legacy--marketing through misinformation and manipulation.
Topics: Amines; Cyclohexanecarboxylic Acids; Drug Industry; Drug Labeling; Gabapentin; gamma-Aminobutyric Acid; History, 20th Century; History, 21st Century; Humans; Marketing; United States; United States Food and Drug Administration | 2009 |
Protective effect of gabapentin on N-methyl-D-aspartate-induced excitotoxicity in rat hippocampal CA1 neurons.
Topics: Amines; Animals; Animals, Newborn; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Ion Channels; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2009 |
Pharmacodynamic and pharmacokinetic interaction profiles of levetiracetam in combination with gabapentin, tiagabine and vigabatrin in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis.
Topics: Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Interactions; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Levetiracetam; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Piracetam; Seizures; Tiagabine; Tissue Distribution; Vigabatrin | 2009 |
Topical analgesic combinations for bortezomib neuropathy.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Amines; Analgesics; Boronic Acids; Bortezomib; Clonidine; Cyclohexanecarboxylic Acids; Drug Combinations; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Gels; Humans; Ketamine; Male; Middle Aged; Pain Measurement; Paraproteinemias; Peripheral Nervous System Diseases; Protease Inhibitors; Pyrazines; Walking | 2009 |
Branched-chain 2-oxoacid transamination increases GABA-shunt metabolism and insulin secretion in isolated islets.
Topics: 4-Aminobutyrate Transaminase; Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Insulin; Insulin Secretion; Islets of Langerhans; Male; Models, Biological; Potassium Chloride; Rats; Rats, Wistar | 2009 |
A multi-drug intoxication fatality involving Xyrem (GHB).
Topics: Amines; Benzhydryl Compounds; Carisoprodol; Central Nervous System Depressants; Cetirizine; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Female; Forensic Toxicology; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Contents; Humans; Middle Aged; Modafinil; Narcolepsy; Sleep Apnea Syndromes; Snoring; Sodium Oxybate; Tramadol; Vitreous Body | 2009 |
Diagnosis of osteochondroma of the mandibular condyle in atypical facial pain: a case report.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mandibular Condyle; Mandibular Neoplasms; Middle Aged; Osteochondroma; Treatment Outcome | 2008 |
Probability of rash related to gabapentin therapy in a child.
Topics: Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Epilepsy; Exanthema; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Urticaria | 2009 |
[New antiepileptic drugs].
Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Oxcarbazepine; Piracetam; Pregabalin; Triazines; Zonisamide | 2009 |
Combination therapy in treatment of peripheral diabetic neuropathy with severe pain in an adolescent patient.
Topics: Administration, Cutaneous; Adolescent; Amines; Analgesics; Carbamazepine; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Therapy, Combination; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Hand; Humans; Male; Treatment Outcome | 2009 |
Oral fixed drug eruption caused by gabapentin.
Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 2009 |
Alopecia associated with gabapentin in the treatment of neuropathic pain.
Topics: Alopecia; Amines; Analgesics, Non-Narcotic; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hair; Humans; Middle Aged; Peripheral Nervous System Diseases; Shoulder Injuries; Shoulder Pain | 2009 |
Gabapentin selectively reduces persistent sodium current in injured type-A dorsal root ganglion neurons.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channel Gating; Male; Membrane Potentials; Nerve Compression Syndromes; Neurons; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channels | 2009 |
Protective effects of gabapentin on allodynia and alpha 2 delta 1-subunit of voltage-dependent calcium channel in spinal nerve-ligated rats.
Topics: Amines; Analgesics; Animals; Calcium Channels; Calcium Channels, L-Type; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Ligation; Male; Neuralgia; Pain Measurement; Protein Subunits; Rats; Rats, Sprague-Dawley; Spinal Nerves; Up-Regulation | 2009 |
Effect of gabapentin on cognitive processes in rats not exposed and exposed to tobacco smoke during fetal life.
Topics: Amines; Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Cognition; Cyclohexanecarboxylic Acids; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Inhalation Exposure; Injections, Intraperitoneal; Memory; Motor Skills; Nicotiana; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Seizures; Smoke; Time Factors | 2008 |
Gabapentin and pregabalin ameliorate mechanical hypersensitivity after spinal cord injury in mice.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hypersensitivity; Mice; Mice, Inbred Strains; Motor Activity; Pregabalin; Recovery of Function; Spinal Cord Injuries; Time Factors | 2009 |
Severe protracted alcohol withdrawal syndrome: prevalence and pharmacological treatment at an inpatient detoxification unit--a naturalistic study.
Topics: Adult; Aged; Alcoholism; Amines; Anticonvulsants; Chlormethiazole; Clonazepam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Humans; Inpatients; Male; Middle Aged; Prevalence; Severity of Illness Index; Substance Withdrawal Syndrome; Treatment Outcome | 2009 |
Intrathecal gabapentin does not act as a hyperpolarization-activated cyclic nucleotide-gated channel activator in the rat formalin test.
Topics: Amines; Analgesics; Animals; Cardiotonic Agents; Cyclic Nucleotide-Gated Cation Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Injections, Spinal; Male; Pain; Potassium Channels; Pyrimidines; Rats; Rats, Sprague-Dawley | 2009 |
Newer antidepressants and gabapentin for hot flashes: an individual patient pooled analysis.
Topics: Amines; Antidepressive Agents; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Placebos; Treatment Outcome | 2009 |
Mechanical allodynia induced by paclitaxel, oxaliplatin and vincristine: different effectiveness of gabapentin and different expression of voltage-dependent calcium channel alpha(2)delta-1 subunit.
Topics: Administration, Oral; Amines; Analgesics, Non-Narcotic; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Behavior, Animal; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Expression; Injections, Spinal; Male; Mice; Mice, Inbred C57BL; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Pain; Peripheral Nervous System Diseases; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; Vincristine | 2009 |
Expanding the peptide beta-turn in alphagamma hybrid sequences: 12 atom hydrogen bonded helical and hairpin turns.
Topics: Amines; Computer Simulation; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen Bonding; Models, Molecular; Peptides; Protein Conformation; Protein Structure, Secondary; Stereoisomerism | 2009 |
Gabapentin responsive audiovestibular paroxysmia.
Topics: Aged, 80 and over; Amines; Central Nervous System Agents; Cranial Nerve Diseases; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Nerve Compression Syndromes; Tinnitus; Vertigo | 2009 |
A mouse model of sural nerve injury-induced neuropathy: gabapentin inhibits pain-related behaviors and the hyperactivity of wide-dynamic range neurons in the dorsal horn.
Topics: Amines; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Cold Temperature; Cyclohexanecarboxylic Acids; Data Interpretation, Statistical; Electrophysiology; Gabapentin; gamma-Aminobutyric Acid; Ligation; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Peripheral Nervous System Diseases; Physical Stimulation; Posterior Horn Cells; Sciatic Nerve; Sciatic Neuropathy; Sural Nerve | 2009 |
Gabapentin versus tricyclics for neuropathic pain.
Topics: Amines; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain Measurement; Randomized Controlled Trials as Topic | 2009 |
Blood serum profiling of the rat spinal nerve ligation model using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry.
Topics: Amines; Analgesics; Animals; Biomarkers; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Ligation; Male; Metabolomics; Multivariate Analysis; Norepinephrine; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Serum; Spinal Nerves; Tandem Mass Spectrometry | 2009 |
[Gabapentin abuse].
Topics: Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Substance-Related Disorders | 2010 |
Antihyperalgesic effect of systemic dexmedetomidine and gabapentin in a rat model of monoarthritis.
Topics: Adjuvants, Immunologic; Amines; Analgesics; Analysis of Variance; Animals; Ankle Joint; Arthritis, Experimental; Cyclohexanecarboxylic Acids; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Inflammation; Injections, Intra-Articular; Male; Motor Activity; Pain Measurement; Pain Threshold; Random Allocation; Rats; Rats, Sprague-Dawley | 2009 |
Conformational choices for the stereochemically constrained gamma-amino acid residue gabapentin: theoretical studies and correlation with experimental results.
Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen Bonding; Models, Theoretical; Molecular Conformation; Molecular Structure | 2009 |
[Obturator nerve lesion after a vaginal delivery without instrumentation under epidural analgesia].
Topics: Adult; Amines; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics; Cyclohexanecarboxylic Acids; Delivery, Obstetric; Drug Therapy, Combination; Female; Gabapentin; Gait Disorders, Neurologic; gamma-Aminobutyric Acid; Humans; Obturator Nerve; Peripheral Nervous System Diseases; Puerperal Disorders; Remission, Spontaneous | 2009 |
Antinociceptive effects of chronic administration of uncompetitive NMDA receptor antagonists in a rat model of diabetic neuropathic pain.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Cyclopentanes; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Memantine; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Streptozocin; Time Factors | 2009 |
Targeted disruption of the voltage-dependent calcium channel alpha2/delta-1-subunit.
Topics: Amines; Animals; Binding Sites; Blotting, Western; Calcium Channels; Calcium Channels, L-Type; Cyclohexanecarboxylic Acids; Electrophysiology; Exons; Gabapentin; gamma-Aminobutyric Acid; Genotype; Heart; Mice; Mice, Knockout; Muscle, Skeletal; Myocardial Contraction; Myocytes, Cardiac; Patch-Clamp Techniques; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Simulations of the nonlinear dose dependence for substrates of influx and efflux transporters in the human intestine.
Topics: Acyclovir; Adrenergic beta-Antagonists; Amines; Animals; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Carrier Proteins; Computer Simulation; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Intestinal Mucosa; Nonlinear Dynamics; Organic Anion Transporters; Permeability; Propanolamines; Rats; Solubility; Valacyclovir; Valine | 2009 |
Is gabapentin an effective treatment choice for hemicrania continua?
Topics: Adult; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Pathways; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Male; Middle Aged; Migraine Disorders; Retrospective Studies; Treatment Outcome; Trigeminal Nerve | 2009 |
Restless legs syndrome.
Topics: Algorithms; Amines; Analgesics, Opioid; Benzodiazepines; Carbidopa; Causality; Cyclohexanecarboxylic Acids; Dopamine Agents; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Levodopa; Middle Aged; Oxycodone; Practice Guidelines as Topic; Restless Legs Syndrome; Treatment Outcome | 2009 |
Anti-nociceptive synergism of morphine and gabapentin in neuropathic pain induced by chronic constriction injury.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Male; Morphine; Neuralgia; Pain; Rats; Rats, Wistar; Sciatic Nerve | 2009 |
Gabapentin therapy for chronic proctalgia following stapled haemorrhoidopexy.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hemorrhoids; Humans; Male; Middle Aged; Pain; Surgical Stapling | 2009 |
Protein kinase A-dependence of the supraspinally mediated analgesic effects of gabapentin on thermal and mechanical hypersensitivity.
Topics: Amines; Analgesics; Animals; Cyclic AMP-Dependent Protein Kinases; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraventricular; Isoquinolines; Locus Coeruleus; Male; Mice; Pain; Pain Measurement; Protein Kinase Inhibitors; Sulfonamides | 2009 |
Gabapentin-induced rhabdomyolysis in a patient with diabetic neuropathy.
Topics: Amines; Anticonvulsants; Creatinine; Cyclohexanecarboxylic Acids; Diabetic Nephropathies; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Muscle, Skeletal; Potassium; Rhabdomyolysis | 2009 |
How does gabapentin relieve neuropathic pain?
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain; Peripheral Nervous System Diseases | 2009 |
Moving from tube to oral feeding in medically fragile nonverbal toddlers.
Topics: Amines; Analgesics; Antidepressive Agents, Tricyclic; Appetite Regulation; Appetite Stimulants; Child Behavior; Child Development; Child, Preschool; Clinical Protocols; Critical Care; Cyclohexanecarboxylic Acids; Eating; Enteral Nutrition; Feeding and Eating Disorders of Childhood; Feeding Behavior; Female; Gabapentin; gamma-Aminobutyric Acid; Gastrostomy; Humans; Infant; Infant Behavior; Male; Megestrol; Motor Skills; Pain | 2009 |
Treatment with carbamazepine and gabapentin of a patient with primary erythermalgia (erythromelalgia) identified to have a mutation in the SCN9A gene, encoding a voltage-gated sodium channel.
Topics: Adolescent; Adult; Amines; Calcium Channel Blockers; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Erythromelalgia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mutation; NAV1.7 Voltage-Gated Sodium Channel; Pain; Pedigree; Sodium Channels | 2009 |
Gabapentin for Kleine-Levin syndrome.
Topics: Adolescent; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Electroencephalography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kleine-Levin Syndrome; Magnetic Resonance Imaging; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 2009 |
Gabapentin for the treatment of pain related to radiation-induced mucositis in patients with head and neck tumors treated with intensity-modulated radiation therapy.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Deglutition Disorders; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Head and Neck Neoplasms; Humans; Male; Mucositis; Pain; Radiotherapy, Intensity-Modulated; Retrospective Studies | 2010 |
Neuropathic pain after stapled hemorrhoidopexy.
Topics: Adult; Amines; Amitriptyline; Anal Canal; Analgesics; Cyclohexanecarboxylic Acids; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Hemorrhoids; Humans; Ligation; Male; Minimally Invasive Surgical Procedures; Pain Measurement; Pain, Postoperative; Proctoscopy; Risk Assessment; Severity of Illness Index; Surgical Stapling; Tomography, X-Ray Computed | 2009 |
[Development or worsening of myoclonus associated with gabapentin therapy].
Topics: Adult; Amines; Anticonvulsants; Contraindications; Cyclohexanecarboxylic Acids; Epilepsy, Tonic-Clonic; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Myoclonus; Practice Guidelines as Topic; Prognosis; Retrospective Studies; Young Adult | 2009 |
Gabapentin-induced delirium and dependence.
Topics: Adult; Amines; Analgesics, Non-Narcotic; Cyclohexanecarboxylic Acids; Delirium; Gabapentin; gamma-Aminobutyric Acid; Herpes Simplex; Humans; Male; Neuralgia; Substance-Related Disorders | 2009 |
Femoral neck stress fracture complicated by deep venous thrombosis and complex regional pain syndrome: a case report.
Topics: Adrenergic Uptake Inhibitors; Adult; Amines; Autonomic Nerve Block; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Female Athlete Triad Syndrome; Femoral Neck Fractures; Fractures, Stress; Gabapentin; gamma-Aminobutyric Acid; Humans; Nortriptyline; Venous Thrombosis | 2009 |
Stability of gabapentin 300-mg capsules repackaged in unit dose containers.
Topics: Amines; Anticonvulsants; Capsules; Cyclohexanecarboxylic Acids; Dosage Forms; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Humans; United States; United States Food and Drug Administration | 2009 |
Gabapentin therapy for pain and irritability in a neurologically impaired infant.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Irritable Mood; Male; Nervous System Diseases; Pain | 2009 |
Pregabalin- and gabapentin-associated myoclonus in a patient with chronic renal failure.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Male; Middle Aged; Myoclonus; Pregabalin | 2009 |
Antinociceptive effects of NCX-701 (nitro-paracetamol) in neuropathic rats: enhancement of antinociception by co-administration with gabapentin.
Topics: Acetaminophen; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Injections, Intravenous; Injections, Spinal; Male; Neuralgia; Nitrates; Pain Measurement; Rats; Rats, Wistar; Spinal Cord | 2009 |
Abnormal gait, due to inflammation but not nerve injury, reflects enhanced nociception in preclinical pain models.
Topics: Amines; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Axotomy; Carrageenan; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Edema; Freund's Adjuvant; Gabapentin; Gait; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Indomethacin; Inflammation; Male; Morphine; Neuralgia; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Thiophenes | 2009 |
A case of perineal pain related to interstitial cystitis which was supposed to be relieved with gabapentin.
Topics: Amines; Analgesics; Anesthetics, Local; Cyclohexanecarboxylic Acids; Cystitis, Interstitial; Cystoscopy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Nerve Block; Pain; Pain Measurement; Perineum | 2009 |
U.S. physician knowledge of the FDA-approved indications and evidence base for commonly prescribed drugs: results of a national survey.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Data Collection; Diabetic Nephropathies; Drug Approval; Drug Labeling; Drug Prescriptions; Drug Utilization Review; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Health Knowledge, Attitudes, Practice; Humans; Off-Label Use; Practice Patterns, Physicians'; United States; United States Food and Drug Administration | 2009 |
Fibromyalgia: poorly understood; treatments are disappointing.
Topics: Acetaminophen; Acupuncture Therapy; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents; Antidepressive Agents, Tricyclic; Chronic Disease; Cognitive Behavioral Therapy; Complementary Therapies; Cyclohexanecarboxylic Acids; Depression; Diagnosis, Differential; Double-Blind Method; Exercise; Fatigue; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Randomized Controlled Trials as Topic; Sleep Wake Disorders; Tramadol; Treatment Outcome | 2009 |
Gabapentin treatment improves motor coordination in a mice model of progressive ataxia.
Topics: Age Factors; Amines; Analysis of Variance; Animals; Ataxia; Atrophy; Cell Count; Cerebellum; Chromatography, High Pressure Liquid; Cyclic Nucleotide-Gated Cation Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Mice; Mice, Knockout; Motor Skills; Potassium Channels; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rotarod Performance Test; Staining and Labeling | 2009 |
SUNCT syndrome or first division trigeminal neuralgia associated with cerebellar hypoplasia.
Topics: Amines; Arnold-Chiari Malformation; Carbamazepine; Cerebellum; Cranial Fossa, Posterior; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Fractures, Bone; Gabapentin; gamma-Aminobutyric Acid; Growth Disorders; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nervous System Malformations; Ophthalmic Nerve; Osteogenesis Imperfecta; SUNCT Syndrome; Treatment Outcome; Trigeminal Neuralgia | 2009 |
An analysis of disease severity based on SMN2 copy number in adults with spinal muscular atrophy.
Topics: Activities of Daily Living; Adult; Amines; Cohort Studies; Cyclohexanecarboxylic Acids; Disability Evaluation; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Gene Dosage; Humans; Male; Middle Aged; Muscle Strength; Muscular Atrophy, Spinal; Phenotype; Respiratory Function Tests; Survival of Motor Neuron 2 Protein | 2009 |
Chorea associated with gabapentin use in an elderly man.
Topics: Aged; Amines; Analgesics; Anti-Dyskinesia Agents; Anxiety; Chorea; Cognition Disorders; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Haloperidol; Humans; Magnetic Resonance Imaging; Male; Memory Disorders; Neuropsychological Tests | 2009 |
Subdiaphragmatic vagotomy promotes nociceptive sensitivity of deep tissue in rats.
Topics: Amines; Amitriptyline; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Diaphragm; Disease Models, Animal; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Morphine; Muscle, Skeletal; Neuronal Plasticity; Nociceptors; Pain Measurement; Pain Threshold; Posterior Horn Cells; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Spinal Cord; Vagotomy; Vagus Nerve; Vagus Nerve Diseases; Visceral Afferents | 2009 |
Neuropathic pain treatment: a further step forward.
Topics: Amines; Analgesics; Antidepressive Agents, Tricyclic; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Discovery; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Nortriptyline; Research Design; Treatment Outcome | 2009 |
The alpha(2)delta subunit augments functional expression and modifies the pharmacology of Ca(V)1.3 L-type channels.
Topics: Acetates; Amines; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Patch-Clamp Techniques; Rabbits; Rats; Recombinant Fusion Proteins | 2009 |
Suppression of formalin-induced nociception by cilnidipine, a voltage-dependent calcium channel blocker.
Topics: Administration, Oral; Amines; Analgesics; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Cyclohexanecarboxylic Acids; Dihydropyridines; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Models, Animal; Nifedipine; omega-Conotoxins; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord | 2009 |
Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis.
Topics: Amines; Animals; Calcium Channels; Calcium Channels, L-Type; CD36 Antigens; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Mice; Neurogenesis; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Synapses | 2009 |
GABA and valproate modulate trigeminovascular nociceptive transmission in the thalamus.
Topics: Amines; Animals; Anticonvulsants; Cerebral Arteries; Cyclohexanecarboxylic Acids; Disease Models, Animal; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Migraine Disorders; Neural Inhibition; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Sensory Receptor Cells; Synaptic Transmission; Trigeminal Nerve; Valproic Acid; Ventral Thalamic Nuclei | 2010 |
Craniotomy pain: trying to do better.
Topics: Administration, Oral; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anticonvulsants; Craniotomy; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; Pain Measurement; Pain, Postoperative; Phenytoin; Preanesthetic Medication; Supratentorial Neoplasms; Time Factors; Treatment Outcome | 2009 |
Pharmacokinetics of oral gabapentin in greyhound dogs.
Topics: Administration, Oral; Amines; Analgesics; Animals; Area Under Curve; Biological Availability; Cyclohexanecarboxylic Acids; Dogs; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Male; Metabolic Clearance Rate | 2011 |
Antiepileptic drugs combined with high-frequency electrical stimulation in the ventral hippocampus modify pilocarpine-induced status epilepticus in rats.
Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electric Stimulation; Electrodes, Implanted; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Lithium Chloride; Male; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Synaptic Transmission | 2010 |
SUNCT syndrome successfully treated with the combination of oxcarbazepine and gabapentin.
Topics: Aged; Amines; Analgesics; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Orbit; SUNCT Syndrome; Thalamus; Treatment Outcome; Trigeminal Nerve; Trigeminal Neuralgia | 2009 |
Prevalence of gabapentin in impaired driving cases in Washington State in 2003-2007.
Topics: Accidents, Traffic; Adult; Aged; Amines; Anticonvulsants; Automobile Driving; Central Nervous System Diseases; Cyclohexanecarboxylic Acids; Female; Forensic Toxicology; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Substance Abuse Detection; Washington; Young Adult | 2009 |
71-year-old man with chronic kidney failure and sudden change of mental status.
Topics: Academic Medical Centers; Aged; Amines; Analgesics; Confusion; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Kidney Function Tests; Male; Mental Disorders; Minnesota; Renal Dialysis; Risk Assessment; Withholding Treatment | 2009 |
Drug-induced encephalopathy secondary to non renal dosing of common medications in Two dialysis patients.
Topics: Acyclovir; Aged; Amines; Analgesics; Antiviral Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Male; Middle Aged; Neurotoxicity Syndromes; Renal Dialysis | 2009 |
Synthesis and in vivo evaluation of 3-substituted gababutins.
Topics: Amines; Amino Acids; Animals; Anti-Anxiety Agents; Calcium Channels; Carrageenan; Cyclohexanecarboxylic Acids; Cyclopentanes; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Rats; Stereoisomerism | 2010 |
Outcome reporting in industry-sponsored trials of gabapentin for off-label use.
Topics: Amines; Bipolar Disorder; Clinical Protocols; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders; Off-Label Use; Outcome Assessment, Health Care; Pain; Publication Bias; Randomized Controlled Trials as Topic; Treatment Outcome | 2009 |
Synthesis and in vivo evaluation of 3,4-disubstituted gababutins.
Topics: Amines; Amino Acids; Animals; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Cyclopentanes; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Rats | 2010 |
Analysis of the antinociceptive interactions in two-drug combinations of gabapentin, oxcarbazepine and amitriptyline in streptozotocin-induced diabetic mice.
Topics: Administration, Oral; Amines; Amitriptyline; Analgesics; Animals; Behavior, Animal; Carbamazepine; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Drug Combinations; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Oxcarbazepine | 2010 |
Gabapentin therapy for ocular opsoclonus-myoclonus restores eye movement communication in a patient with a locked-in syndrome.
Topics: Adult; Amines; Anticonvulsants; Cerebral Infarction; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Ocular Motility Disorders; Opsoclonus-Myoclonus Syndrome; Pons; Quadriplegia | 2010 |
Synthesis and in vivo evaluation of bicyclic gababutins.
Topics: Amines; Amino Acids; Animals; Blood-Brain Barrier; Bridged Bicyclo Compounds; CHO Cells; Cricetinae; Cricetulus; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Neuralgia; Pain Measurement; Rats; Stereoisomerism; Structure-Activity Relationship | 2010 |
Single dose of preoperative analgesia with gabapentin (600 mg) is safe and effective in monitored anesthesia care for nasal surgery.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Monitoring; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Male; Middle Aged; Otorhinolaryngologic Surgical Procedures; Preoperative Care; Young Adult | 2010 |
Renewing relationships. Treating sexual pain in women.
Topics: Amines; Analgesics; Antidepressive Agents, Tricyclic; Biofeedback, Psychology; Botulinum Toxins, Type A; Capsaicin; Causality; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuromuscular Agents; Nurse Practitioners; Nurse's Role; Nursing Assessment; Patient Education as Topic; Physical Examination; Physical Therapy Modalities; Referral and Consultation; Vulvar Vestibulitis | 2007 |
Gabapentin use in hyperemesis gravidarum: a pilot study.
Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperemesis Gravidarum; Pilot Projects; Pregnancy; Treatment Outcome | 2010 |
[Efficacy of gabapentin in patients with discogenic lumbosacral radiculopathy].
Topics: Administration, Oral; Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Lumbosacral Region; Male; Middle Aged; Pain Measurement; Radiculopathy; Sacrum; Treatment Outcome | 2009 |
[Neurological symptoms following lightening strike].
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Lightning Injuries; Male; Middle Aged; Polyneuropathies; Treatment Outcome | 2009 |
Comparative placebo-controlled polysomnographic and psychometric studies on the acute effects of gabapentin versus ropinirole in restless legs syndrome.
Topics: Amines; Anti-Dyskinesia Agents; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Male; Mental Processes; Middle Aged; Placebos; Polysomnography; Psychometrics; Respiration; Restless Legs Syndrome; Single-Blind Method; Sleep; Sleep Stages; Sleep, REM; Time Factors; Treatment Outcome | 2010 |
Neuronal hyperactivity at the spinal cord and periaqueductal grey during painful diabetic neuropathy: effects of gabapentin.
Topics: Amines; Analgesics; Analysis of Variance; Animals; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Neurons; Periaqueductal Gray; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spinal Cord | 2010 |
Gabapentin (Neurontin) improves pain scores of patients with critical limb ischaemia: an observational study.
Topics: Aged; Amines; Analgesics; Analgesics, Opioid; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ischemia; Leg; Male; Pain; Pain Measurement | 2010 |
[Treatment of neuropathies].
Topics: Adjuvants, Immunologic; Adrenergic Uptake Inhibitors; Amines; Analgesics; Antioxidants; Capsaicin; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Polyneuropathies; Pregabalin; Sensory System Agents; Thiamine; Thioctic Acid; Thiophenes | 2010 |
Novel long-term anticonvulsant treatment with gabapentin without causing memory impairment in mice.
Topics: Amines; Animals; Anticonvulsants; Cognition Disorders; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Memory Disorders; Mice | 2010 |
Tri-partite complex for axonal transport drug delivery achieves pharmacological effect.
Topics: Amines; Analgesics; Animals; Axonal Transport; Cell Line; Cells, Cultured; Cricetinae; Cyclohexanecarboxylic Acids; Dextrans; Dose-Response Relationship, Drug; Drug Delivery Systems; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Macaca fascicularis; Models, Neurological; Nanoparticles; Nerve Growth Factor; Neurons; Pain; Polymers; Rabbits; Rats; Rats, Sprague-Dawley; Wheat Germ Agglutinins | 2010 |
Treatments for neuropathic pain differentially affect delayed matching accuracy by macaques: effects of amitriptyline and gabapentin.
Topics: Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Macaca nemestrina; Male; Memory, Short-Term; Neuralgia; Neuropsychological Tests; Psychomotor Performance; Reaction Time | 2010 |
Therapy: nonhormonal treatment of hot flashes-a viable alternative?
Topics: Adrenergic Uptake Inhibitors; Amines; Antidepressive Agents; Breast Neoplasms; Contraindications; Cyclohexanecarboxylic Acids; Estrogen Replacement Therapy; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Tamoxifen | 2010 |
Epicrania fugax: ten new cases and therapeutic results.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Cluster Headache; Cyclohexanecarboxylic Acids; Diagnostic Imaging; Female; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders; Humans; Lamotrigine; Male; Middle Aged; Nerve Block; Pain Measurement; Treatment Outcome; Triazines; Young Adult | 2010 |
Cardiopulmonary bypass does not affect plasma concentration of preoperatively administered gabapentin.
Topics: Aged; Amines; Analgesics; Cardiopulmonary Bypass; Cohort Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Monitoring; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Preoperative Care; Time Factors; Treatment Outcome | 2010 |
Substitution of gabapentin therapy with pregabalin therapy in neuropathic pain due to peripheral neuropathy.
Topics: Aged; Amines; Analgesics; Cohort Studies; Cyclohexanecarboxylic Acids; Data Interpretation, Statistical; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Peripheral Nervous System Diseases; Pregabalin; Quality of Life; Treatment Outcome | 2010 |
Expression of COUP-TFII nuclear receptor in restricted GABAergic neuronal populations in the adult rat hippocampus.
Topics: Amines; Animals; Axons; Cell Adhesion Molecules, Neuronal; Cell Lineage; COUP Transcription Factor II; Cyclohexanecarboxylic Acids; Extracellular Matrix Proteins; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Male; Nerve Net; Nerve Tissue Proteins; Neuroglia; Neurons; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA; Reelin Protein; Serine Endopeptidases | 2010 |
Chemical composition and evaluation of the anti-hypernociceptive effect of the essential oil extracted from the leaves of Ugni myricoides on inflammatory and neuropathic models of pain in mice.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Bicyclic Monoterpenes; Carrageenan; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Indomethacin; Inflammation; Mice; Monoterpenes; Myrtaceae; Neuralgia; Oils, Volatile; Phytotherapy; Plant Extracts; Plant Leaves; Sciatic Neuropathy | 2010 |
Cost effectiveness of pregabalin in the treatment of fibromyalgia from a UK perspective.
Topics: Adult; Amines; Amitriptyline; Analgesics; Antidepressive Agents; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Drug Costs; Duloxetine Hydrochloride; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Markov Chains; Models, Econometric; Pregabalin; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Thiophenes; Tramadol; United Kingdom | 2010 |
The rise and fall of gabapentin for bipolar disorder: a case study on off-label pharmaceutical diffusion.
Topics: Adolescent; Adult; Amines; Anti-Anxiety Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Evidence-Based Medicine; Female; Florida; Gabapentin; gamma-Aminobutyric Acid; Humans; Information Dissemination; Logistic Models; Male; Marketing of Health Services; Medicaid; Middle Aged; Observation; Off-Label Use; United States; Young Adult | 2010 |
Temporal response to bupivacaine bilateral great occipital block in a patient with SUNCT syndrome.
Topics: Aged, 80 and over; Amines; Anesthetics, Local; Anticonvulsants; Bupivacaine; Cyclohexanecarboxylic Acids; Facial Pain; Female; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nerve Block; Occipital Bone; Spinal Nerves; SUNCT Syndrome; Time Factors; Treatment Outcome; Triazines | 2010 |
[Interaction between gabapentin and D-serin in the formalin orofacial test].
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Drug Interactions; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Male; Pain Measurement; Rats; Rats, Wistar; Serine | 2009 |
Methamphetamine-induced up-regulation of α2/δ subunit of voltage-gated calcium channels is regulated by DA receptors.
Topics: Amines; Analysis of Variance; Animals; Benzazepines; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Central Nervous System Stimulants; Cerebral Cortex; Conditioning, Operant; Cyclohexanecarboxylic Acids; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Male; Methamphetamine; Mice; Mice, Inbred Strains; Neurons; Protein Subunits; Receptors, Dopamine; Sulpiride; Up-Regulation | 2010 |
Syringomyelia in the Cavalier King Charles spaniel (CKCS) dog.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents; Arnold-Chiari Malformation; Breeding; Cyclohexanecarboxylic Acids; Disease Progression; Dog Diseases; Dogs; Female; Gabapentin; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Male; Pain; Prednisone; Prognosis; Quality of Life; Severity of Illness Index; Syringomyelia | 2010 |
In vitro effects of antiepileptic drugs on acetylcholinesterase and ectonucleotidase activities in zebrafish (Danio rerio) brain.
Topics: 5'-Nucleotidase; Acetylcholinesterase; Amines; Animals; Anticonvulsants; Brain; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Phenytoin; Zebrafish | 2010 |
Gabapentin toxicity in patients with chronic kidney disease: a preventable cause of morbidity.
Topics: Adult; Age Distribution; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Glomerular Filtration Rate; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Retrospective Studies | 2010 |
Simultaneous HPLC-F analysis of three recent antiepileptic drugs in human plasma.
Topics: Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dansyl Compounds; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Spectrometry, Fluorescence; Topiramate; Vigabatrin | 2010 |
Brain perfusion in fibromyalgia patients and its differences between responders and poor responders to gabapentin.
Topics: Adult; Aged; Amines; Analgesics; Brain; Cerebrovascular Circulation; Cyclohexanecarboxylic Acids; Cysteine; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Organotechnetium Compounds; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon; Treatment Failure; Young Adult | 2010 |
Comparison of perioperative oral multimodal analgesia versus IV PCA for spine surgery.
Topics: Acetaminophen; Administration, Oral; Amines; Analgesia; Analgesia, Patient-Controlled; Analgesics; Arthroplasty; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Injections, Intravenous; Male; Oxycodone; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Preoperative Care; Prospective Studies; Quinolizines; Spine; Treatment Outcome | 2010 |
Spectrophotometric determination of gabapentin in pharmaceutical formulations using ninhydrin and pi-acceptors.
Topics: Amines; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrocarbons, Aromatic; Indicators and Reagents; Kinetics; Limit of Detection; Linear Models; Magnetic Resonance Spectroscopy; Ninhydrin; Pharmaceutical Preparations; Spectrophotometry; Thermodynamics | 2010 |
Comparative effectiveness of 10 antiepileptic drugs in older adults with epilepsy.
Topics: Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Resistance; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Treatment Outcome; Triazines | 2010 |
Management of recurrent laryngeal sensory neuropathic symptoms.
Topics: Adrenergic Uptake Inhibitors; Aged; Amines; Amitriptyline; Cough; Cranial Nerve Diseases; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Laryngoscopy; Male; Middle Aged; Neurotransmitter Agents; Recurrent Laryngeal Nerve; Retrospective Studies; Treatment Outcome | 2010 |
Gabapentin in the treatment of hiccups in patients with advanced cancer: a 5-year experience.
Topics: Adult; Aged; Aged, 80 and over; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Male; Middle Aged; Neoplasms; Retrospective Studies; Time Factors | 2010 |
Hollow fiber-based liquid phase microextraction combined with high-performance liquid chromatography for the analysis of gabapentin in biological samples.
Topics: Amines; Analgesics; Chemical Fractionation; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Filtration; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Spectrophotometry, Ultraviolet | 2010 |
Analgesic effects of gabapentin on mechanical hypersensitivity in a rat model of chronic pancreatitis.
Topics: Amines; Analgesics; Animals; Calcium Channels; Calcium Channels, L-Type; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Immunosuppressive Agents; Male; Organotin Compounds; Pain; Pain Measurement; Pancreatitis, Chronic; Rats; Rats, Inbred WF | 2010 |
Effect of analgesic standards on persistent postoperative pain evoked by skin/muscle incision and retraction (SMIR).
Topics: Amines; Analgesics; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Dermatologic Surgical Procedures; Disease Models, Animal; Dizocilpine Maleate; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Male; Morphine; Muscle, Skeletal; Pain Measurement; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Touch | 2010 |
Reporting of trials of gabapentin.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Off-Label Use; Randomized Controlled Trials as Topic; Trauma, Nervous System; Treatment Outcome | 2010 |
Meningioma causing gabapentin-responsive secondary SUNCT syndrome.
Topics: Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Meningeal Neoplasms; Meningioma; SUNCT Syndrome | 2010 |
Studies of synergy between morphine and a novel sodium channel blocker, CNSB002, in rat models of inflammatory and neuropathic pain.
Topics: Amines; Analgesics, Opioid; Animals; Carrageenan; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dose-Response Relationship, Drug; Drug Synergism; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Inflammation; Male; Morphine; Motor Activity; Pain; Pain Measurement; Peripheral Nervous System Diseases; Piperazines; Rats; Rats, Wistar; Sodium Channel Blockers | 2010 |
Teaching case: menopausal migraine.
Topics: Amines; Cyclohexanecarboxylic Acids; Cyclohexanols; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Herbal Medicine; Hot Flashes; Humans; Menstrual Cycle; Menstruation Disturbances; Middle Aged; Migraine Disorders; Postmenopause; Topiramate; Venlafaxine Hydrochloride | 2010 |
Progressive steps of polymorphic transformation of gabapentin polymorphs studied by hot-stage FTIR microspectroscopy.
Topics: Amines; Anticonvulsants; Calorimetry, Differential Scanning; Crystallization; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Spectroscopy, Fourier Transform Infrared; Thermogravimetry; X-Ray Diffraction | 2010 |
Pharmacological prophylaxis of chronic migraine: a review of double-blind placebo-controlled trials.
Topics: Amines; Analgesics; Chronic Disease; Clonidine; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Double-Blind Method; Fructose; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders; Randomized Controlled Trials as Topic; Topiramate; Valproic Acid | 2010 |
A case of erythromelalgia: good response to treatment with gabapentin.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Erythromelalgia; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Treatment Outcome; Young Adult | 2010 |
Withdrawal symptoms after gabapentin discontinuation.
Topics: Amines; Anticonvulsants; Benzodiazepines; Cyclohexanecarboxylic Acids; Ethanol; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Substance Withdrawal Syndrome | 2010 |
Advancing the scheduled time of hemodialysis is benificial for maintenance hemodialysis patients with gabapentin intolerance.
Topics: Aged; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Muscle Weakness; Renal Dialysis; Speech Disorders; Uremia | 2010 |
New uses for older drugs: the tales of aspirin, thalidomide, and gabapentin.
Topics: Amines; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Aspirin; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neoplasms; Peripheral Nervous System Diseases; Thalidomide | 2010 |
Opsoclonus-myoclonus syndrome in patients with locked-in syndrome: a therapeutic porthole with gabapentin.
Topics: Aged; Amines; Cyclohexanecarboxylic Acids; Eye Movements; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nonverbal Communication; Opsoclonus-Myoclonus Syndrome; Quadriplegia | 2010 |
The multidisciplinary management of menopausal symptoms after breast cancer: a unique model of care.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care Facilities; Amines; Anti-Anxiety Agents; Breast Neoplasms; Clonidine; Cyclohexanecarboxylic Acids; Cyclohexanols; Fatigue; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Libido; Menopause; Middle Aged; Patient Care Team; Patient Education as Topic; Patient Satisfaction; Patient-Centered Care; Practice Guidelines as Topic; Referral and Consultation; Selective Serotonin Reuptake Inhibitors; Sleep Wake Disorders; Sweating; Sympatholytics; Venlafaxine Hydrochloride; Vitamin E; Vitamins | 2010 |
Gabapentin for spasticity and autonomic dysreflexia after severe spinal cord injury.
Topics: Amines; Animals; Autonomic Dysreflexia; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Muscle Spasticity; Rats; Rats, Wistar; Severity of Illness Index; Spinal Cord Injuries | 2011 |
Gabapentin-induced delusions of parasitosis.
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Delusions; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia, Postherpetic; Skin Diseases, Parasitic | 2010 |
The effects of intravenous gabapentin administration on the minimum alveolar concentration of isoflurane in cats.
Topics: Amines; Analgesics; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Blood Pressure; Body Temperature; Cats; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Injections, Intravenous; Isoflurane; Pulmonary Alveoli; Tandem Mass Spectrometry | 2010 |
Solid-state transformation of different gabapentin polymorphs upon milling and co-milling.
Topics: Amines; Analgesics; Anticonvulsants; Chemistry, Pharmaceutical; Crystallization; Cyclohexanecarboxylic Acids; Drug Stability; Excipients; Gabapentin; gamma-Aminobutyric Acid; Microspectrophotometry; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; Time Factors; Water | 2010 |
Selective potentiation of gabapentin-mediated antinociception in the rat formalin test by the nicotinic acetylcholine receptor agonist ABT-594.
Topics: Amines; Analgesics; Animals; Azetidines; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Duloxetine Hydrochloride; Exploratory Behavior; Gabapentin; gamma-Aminobutyric Acid; Male; Mecamylamine; Morphine; Nicotinic Agonists; Nicotinic Antagonists; Pain; Pain Measurement; Pyridines; Rats; Rats, Sprague-Dawley; Thiophenes | 2010 |
Hybrid polypeptides: gabapentin as a stereochemically constrained γ-amino acid residue.
Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen Bonding; Peptides; Protein Folding; Protein Structure, Secondary | 2010 |
Gabapentin for the treatment of pain syndrome related to radiation-induced mucositis in patients with head and neck cancer treated with concurrent chemoradiotherapy.
Topics: Amines; Analgesics; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Head and Neck Neoplasms; Humans; Male; Mucositis; Pain; Radiotherapy, Intensity-Modulated | 2010 |
Non-length-dependent small fibre neuropathy. Confocal microscopy study of the corneal innervation.
Topics: Adult; Amines; Amitriptyline; Analgesics; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Biopsy; Cornea; Crohn Disease; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Electrophysiology; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Microscopy, Confocal; Middle Aged; Nerve Endings; Nerve Fibers; Peripheral Nervous System Diseases; Sensation Disorders; Sjogren's Syndrome; Skin; Thiophenes; Trigeminal Nerve | 2010 |
Gabapentin-induced exacerbation of myasthenia gravis.
Topics: Aged; Amines; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Gastroesophageal Reflux; Herpes Zoster; Humans; Magnetic Resonance Imaging; Male; Myasthenia Gravis; Pyridostigmine Bromide; Tomography, X-Ray Computed | 2010 |
Gabapentin suppresses cortical spreading depression susceptibility.
Topics: Amines; Anesthesia; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Cortical Spreading Depression; Cyclohexanecarboxylic Acids; Electroencephalography; Electrophysiology; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Injections, Intravenous; Male; Potassium Chloride; Rats; Rats, Sprague-Dawley | 2010 |
Pharmacokinetics of gabapentin in cats.
Topics: Administration, Oral; Amines; Anesthesia; Animals; Anticonvulsants; Cats; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Injections, Intravenous; Kinetics; Ovariectomy | 2010 |
Genotoxic evaluation of antiepileptic drugs by Drosophila somatic mutation and recombination test.
Topics: Abnormalities, Drug-Induced; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drosophila melanogaster; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Mutagenicity Tests; Mutagens; Phenytoin; Pregabalin; Recombination, Genetic; Survival; Wings, Animal | 2010 |
Effective and cost-effective clinical trial recruitment strategies for postmenopausal women in a community-based, primary care setting.
Topics: Advertising; Aged; Amines; Calcium Channel Blockers; Clinical Trials as Topic; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Middle Aged; Newspapers as Topic; Ontario; Patient Selection; Physicians, Family; Postmenopause; Primary Health Care; Program Evaluation; Retrospective Studies | 2010 |
Brachioradial pruritus successfully treated with gabapentin.
Topics: Amines; Cyclohexanecarboxylic Acids; Dermatologic Agents; Forearm; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pruritus; Radiography; Spinal Stenosis | 2010 |
Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Indoles; Injections, Spinal; Ligation; Ondansetron; Pain; Quinolizines; Rats; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Spinal Nerves | 2010 |
A tropomyosine receptor kinase inhibitor blocks spinal neuroplasticity essential for the anti-hypersensitivity effects of gabapentin and clonidine in rats with peripheral nerve injury.
Topics: Acetylcholine; Amines; Analgesics; Animals; Carbazoles; Choline O-Acetyltransferase; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dopamine beta-Hydroxylase; Enzyme Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Indole Alkaloids; Male; Neuralgia; Neuronal Plasticity; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Spinal Nerves; Synaptosomes; Time Factors | 2011 |
[Neuropathic pain in children].
Topics: Adolescent; Amines; Amitriptyline; Analgesics; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Child; Child, Preschool; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Neuralgia; Pain Measurement; Patient Care Team; Risk Factors | 2010 |
Above-level mechanical hyperalgesia in rats develops after incomplete spinal cord injury but not after cord transection, and is reversed by amitriptyline, morphine and gabapentin.
Topics: Amines; Amitriptyline; Analgesics; Animals; Cell Count; Cross-Over Studies; Cyclohexanecarboxylic Acids; Disease Models, Animal; Double-Blind Method; Early Growth Response Protein 1; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation; Hyperalgesia; Male; Morphine; Pain Threshold; Phosphopyruvate Hydratase; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 2010 |
Pregabalin and gabapentin in matched patients with peripheral neuropathic pain in routine medical practice in a primary care setting: Findings from a cost-consequences analysis in a nested case-control study.
Topics: Aged; Amines; Analgesics; Case-Control Studies; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Costs; Efficiency; Female; Gabapentin; gamma-Aminobutyric Acid; Health Care Costs; Humans; Male; Middle Aged; Pain Measurement; Peripheral Nervous System Diseases; Pregabalin; Primary Health Care | 2010 |
Signal transduction, plasma membrane calcium movements, and pigment translocation in freshwater shrimp chromatophores.
Topics: Amines; Animals; Cadmium Chloride; Calcium; Calcium Channels; Cell Membrane; Chromatophores; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Lanthanum; Membrane Potentials; Oligopeptides; omega-Conotoxins; Ouabain; Palaemonidae; Pyrrolidonecarboxylic Acid; Signal Transduction | 2010 |
Comparing healthcare costs of Medicaid patients with postherpetic neuralgia (PHN) treated with lidocaine patch 5% versus gabapentin or pregabalin.
Topics: Amines; Analgesics; Costs and Cost Analysis; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Health Care Costs; Health Services; Humans; Insurance Claim Review; Lidocaine; Male; Medicaid; Middle Aged; Neuralgia, Postherpetic; Pregabalin; Retrospective Studies; Transdermal Patch; United States | 2010 |
Dried plasma spots as an alternative sample collection technique for the quantitative LC-MS/MS determination of gabapentin.
Topics: Amines; Calibration; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Reproducibility of Results; Tandem Mass Spectrometry | 2010 |
Behavioral signs of chronic back pain in the SPARC-null mouse.
Topics: Age Factors; Amines; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Chronic Disease; Cold Temperature; Cyclohexanecarboxylic Acids; Dexamethasone; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Humans; Hyperalgesia; Intervertebral Disc Degeneration; Low Back Pain; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Morphine; Motor Activity; Osteonectin; Stress, Mechanical | 2011 |
Gabapentin reduces neurovisceral pain of porphyria.
Topics: Abdomen, Acute; Amines; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; Porphyria, Acute Intermittent; Young Adult | 2010 |
Gabapentin withdrawal syndrome in a post-liver transplant patient.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Liver Transplantation; Male; Peripheral Nervous System Diseases; Substance Withdrawal Syndrome | 2010 |
Gabapentin completely attenuated the acute morphine-induced c-Fos expression in the rat nucleus accumbens.
Topics: Amines; Analgesics, Opioid; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Morphine; Neurons; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 2011 |
Characterization of the acute and persistent pain state present in K/BxN serum transfer arthritis.
Topics: Activating Transcription Factor 3; Amines; Analgesics; Analysis of Variance; Animals; Arthritis, Rheumatoid; Astrocytes; Autoantibodies; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Glucose-6-Phosphate Isomerase; Knee Joint; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Transgenic; Microglia; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Receptors, Antigen, T-Cell; Serum; Spinal Cord; Time Factors | 2010 |
Thermal antinociceptive effect of orally administered gabapentin in healthy cats.
Topics: Administration, Oral; Amines; Analgesics; Animals; Body Temperature; Cats; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Kinetics; Ovariectomy; Placebos; Skin Temperature | 2010 |
Treatment choice, duration, and cost in patients with interstitial cystitis and painful bladder syndrome.
Topics: Administration, Intravesical; Administration, Oral; Adrenergic Uptake Inhibitors; Adult; Aged; Amines; Amitriptyline; Anticoagulants; Cyclohexanecarboxylic Acids; Cystitis, Interstitial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Muscarinic Antagonists; Narcotics; Pentosan Sulfuric Polyester; Practice Patterns, Physicians'; Treatment Outcome; Young Adult | 2011 |
Synthesis and in vitro evaluation of gabapentin prodrugs that target the human apical sodium-dependent bile acid transporter (hASBT).
Topics: Amines; Animals; Anticonvulsants; Bile Acids and Salts; Biological Transport; Caco-2 Cells; Cell Line; Chenodeoxycholic Acid; Cyclohexanecarboxylic Acids; Dogs; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Kidney; Microsomes, Liver; Organic Anion Transporters, Sodium-Dependent; Prodrugs; Rats; Symporters; Transfection | 2011 |
Gabapentin as part of multimodal analgesia in a newborn with epidermolysis bullosa.
Topics: Amines; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epidermolysis Bullosa; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Pain Measurement; Skin | 2010 |
The alpha2delta ligand gabapentin inhibits the Rab11-dependent recycling of the calcium channel subunit alpha2delta-2.
Topics: Amines; Animals; Calcium Channels; Cell Line; Cell Membrane; Cyclohexanecarboxylic Acids; Electrophysiology; Gabapentin; gamma-Aminobutyric Acid; GTP-Binding Proteins; Humans; Immunohistochemistry; Neurons; Protein Transport; Rats; Rats, Sprague-Dawley | 2010 |
Pharmacokinetics of oral gabapentin alone or co-administered with meloxicam in ruminant beef calves.
Topics: Administration, Oral; Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Cattle; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Kinetics; Male; Meloxicam; Thiazines; Thiazoles | 2011 |
Intrathecal gabapentin and clonidine synergistically inhibit allodynia in spinal nerve-ligated rats.
Topics: Amines; Animals; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Ligation; Male; Neuralgia; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Nerves | 2010 |
Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Child; China; Clonazepam; Cyclohexanecarboxylic Acids; Exanthema; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Medicine, Chinese Traditional; Middle Aged; Phenobarbital; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Triazines; Valproic Acid; Young Adult | 2010 |
Low dose of donepezil improves gabapentin analgesia in the rat spared nerve injury model of neuropathic pain: single and multiple dosing studies.
Topics: Amines; Analgesics; Animals; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Disease Models, Animal; Donepezil; Drug Administration Schedule; Drug Combinations; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Indans; Male; Neuralgia; Peripheral Nervous System Diseases; Piperidines; Rats; Rats, Sprague-Dawley | 2010 |
Gabapentin and suicide attempts.
Topics: Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Databases, Factual; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Logistic Models; Male; Mental Disorders; Middle Aged; Pharmacoepidemiology; Suicide, Attempted; United States; United States Food and Drug Administration; Young Adult | 2010 |
Neuroprotective effects of gabapentin in experimental spinal cord injury.
Topics: Amines; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cyclohexanecarboxylic Acids; Disease Models, Animal; Excitatory Amino Acid Antagonists; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Male; Neuroprotective Agents; Random Allocation; Rats; Rats, Wistar; Spinal Cord Injuries; Treatment Outcome | 2010 |
A novel rat forelimb model of neuropathic pain produced by partial injury of the median and ulnar nerves.
Topics: Amines; Analgesics; Animals; Behavior, Animal; CD11b Antigen; Cold Temperature; Cyclohexanecarboxylic Acids; Disease Models, Animal; Forelimb; Gabapentin; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Hot Temperature; Humans; Hyperalgesia; Male; Median Nerve; Neuralgia; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Ulnar Nerve | 2011 |
The importance of early diagnosis of herpes zoster myelitis.
Topics: Acyclovir; Aged; Amines; Analgesics; Anti-Inflammatory Agents; Antiviral Agents; Cyclohexanecarboxylic Acids; Early Diagnosis; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Magnetic Resonance Imaging; Methylprednisolone; Myelitis, Transverse; Neuralgia, Postherpetic; Paresthesia; Urinary Retention | 2010 |
Treatment of neuropathic itch possibly due to trigeminal trophic syndrome with 0.1% topical tacrolimus and gabapentin.
Topics: Administration, Cutaneous; Amines; Analgesics; Antipruritics; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunosuppressive Agents; Middle Aged; Pruritus; Tacrolimus; Treatment Outcome; Trigeminal Neuralgia | 2010 |
Molecular basis for the dosing time-dependency of anti-allodynic effects of gabapentin in a mouse model of neuropathic pain.
Topics: Amines; Animals; Calcium Channels; Circadian Rhythm; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Mice; Neuralgia; Protein Subunits; Time Factors | 2010 |
Rhinologic evaluation in patients with primary headache.
Topics: Adolescent; Adult; Amines; Antidepressive Agents, Tricyclic; Cyclohexanecarboxylic Acids; Endoscopy; Excitatory Amino Acid Antagonists; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders, Primary; Humans; Male; Middle Aged; Migraine Disorders; Nasal Cavity; Nasal Mucosa; Nasal Septum; Neurologic Examination; Nose Diseases; Pain Measurement; Physical Examination; Prospective Studies; Tension-Type Headache; Tomography, X-Ray Computed; Tryptamines; Turbinates; Young Adult | 2010 |
Gabapentin and pregabalin inhibit the itch-associated response induced by the repeated application of oxazolone in mice.
Topics: Amines; Animals; Calcium Channels; Chronic Disease; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Eruptions; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Injections, Spinal; Male; Mice; Mice, Inbred BALB C; Oxazolone; Pregabalin; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Time Factors; Up-Regulation; Urticaria | 2011 |
Effects of gabapentin on brain hyperactivity related to pain and sleep disturbance under a neuropathic pain-like state using fMRI and brain wave analysis.
Topics: Amines; Analgesics; Animals; Axotomy; Brain; Brain Mapping; Brain Waves; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Magnetic Resonance Imaging; Magnetoencephalography; Male; Mice; Mice, Inbred C57BL; Neuralgia; Pain Measurement; Sciatic Nerve; Sleep Wake Disorders | 2011 |
Amisulpride-induced seizurogenic effect: a potential role of opioid receptor-linked transduction systems.
Topics: Amines; Amisulpride; Analysis of Variance; Animals; Anti-Asthmatic Agents; Cromolyn Sodium; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Naloxone; Receptors, GABA; Receptors, Histamine H1; Receptors, Opioid; Seizures; Sulpiride | 2011 |
Endogenous enkephalin does not contribute to the cerebral anti-hyperalgesic action of gabapentin.
Topics: Amines; Animals; Cerebral Cortex; Cyclohexanecarboxylic Acids; Enkephalins; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Mice; Mice, Inbred BALB C; Pain Measurement | 2010 |
Solubilization of gabapentin into HII mesophases.
Topics: Amines; Calorimetry, Differential Scanning; Caprylates; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glycerides; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Conformation; Scattering, Small Angle; Solubility; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Triglycerides; Water | 2011 |
Gabapentin blocks methamphetamine-induced sensitization and conditioned place preference via inhibition of α₂/δ-1 subunits of the voltage-gated calcium channels.
Topics: Amines; Animals; Blotting, Western; Brain; Calcium Channels; Central Nervous System Stimulants; Conditioning, Psychological; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Methamphetamine; Mice; Motor Activity; Protein Subunits; Protein Transport; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substance-Related Disorders | 2011 |
A case of post-herpetic itch resolved with gabapentin.
Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Pruritus | 2011 |
Acquired neuromyotonia as a paraneoplastic manifestation of ovarian cancer.
Topics: Amines; Anticonvulsants; Antineoplastic Agents, Hormonal; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Isaacs Syndrome; Middle Aged; Ovarian Neoplasms; Paraneoplastic Polyneuropathy; Prednisone | 2011 |
Hip pain as initial presentation for varicella-zoster infection in an adolescent male.
Topics: Acyclovir; Adolescent; Amines; Analgesics; Antiviral Agents; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Hip; Hip Joint; Humans; Low Back Pain; Male; Treatment Outcome | 2011 |
Is there a recreational misuse potential for pregabalin? Analysis of anecdotal online reports in comparison with related gabapentin and clonazepam data.
Topics: Amines; Anticonvulsants; Clonazepam; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Routes; Drug and Narcotic Control; Drug Interactions; Europe; Gabapentin; gamma-Aminobutyric Acid; Humans; Illicit Drugs; Pregabalin; Substance Withdrawal Syndrome; Substance-Related Disorders | 2011 |
Calcium channel alpha-2-delta-1 protein upregulation in dorsal spinal cord mediates spinal cord injury-induced neuropathic pain states.
Topics: Amines; Analgesics; Animals; Calcium Channels; Calcium Channels, L-Type; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Motor Activity; Neuralgia; Oligodeoxyribonucleotides, Antisense; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Statistics as Topic; Time Factors; Up-Regulation | 2011 |
[Pharmacological treatment of nystagmus].
Topics: 4-Aminopyridine; Amines; Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Dopamine Agents; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Muscle Relaxants, Central; Nystagmus, Pathologic; Potassium Channel Blockers | 2011 |
Gabapentin, A GABA analogue, enhances cognitive performance in mice.
Topics: Amines; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Cognition; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Mice; Neuropsychological Tests; Reaction Time | 2011 |
Oscillatory eye movements resembling pendular nystagmus in normal juvenile macaques.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Macaca; Nystagmus, Pathologic; Pursuit, Smooth; Saccades | 2011 |
Simultaneous quantification of levetiracetam and gabapentin in plasma by ultra-pressure liquid chromatography coupled with tandem mass spectrometry detection.
Topics: Amines; Anticonvulsants; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Gabapentin; gamma-Aminobutyric Acid; Humans; Levetiracetam; Piracetam; Reproducibility of Results; Tandem Mass Spectrometry | 2011 |
Neuropathic pain during treatment for childhood acute lymphoblastic leukemia.
Topics: Adolescent; Amines; Analgesics; Analgesics, Opioid; Antineoplastic Agents; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; History, Ancient; Humans; Incidence; Male; Neuralgia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retrospective Studies; Risk Factors; Vincristine | 2011 |
Paroxysmal arousals and myoclonic movements associated with interictal epileptiform discharges in NREM and REM sleep.
Topics: Adolescent; Amines; Antiparkinson Agents; Arousal; Chromosome Disorders; Chromosome Inversion; Chromosomes, Human, Pair 9; Chromosomes, Human, X; Cyclohexanecarboxylic Acids; Diphenhydramine; Electroencephalography; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Intellectual Disability; Myoclonus; Polysomnography; Sleep; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders; Sleep, REM | 2011 |
Sensitive and selective spectrophotometric assay of gabapentin in capsules using sodium 1, 2-naphthoquinone-4-sulfonate.
Topics: Amines; Anticonvulsants; Buffers; Capsules; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Naphthoquinones; Pharmaceutical Preparations; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry | 2011 |
Effect of combined treatment of thioperamide with some antiepileptic drugs on methionine-sulfoximine induced convulsions in mice.
Topics: Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Drug Combinations; Gabapentin; gamma-Aminobutyric Acid; Male; Methionine Sulfoximine; Mice; Piperidines; Seizures; Valproic Acid | 2010 |
[The crystalline polymorph control and selection of gabapentin with polymer heteronuclei].
Topics: Amines; Anticonvulsants; Calorimetry, Differential Scanning; Crystallization; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Molecular Structure; Polymers; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2010 |
Gabapentin promotes inhibition by enhancing hyperpolarization-activated cation currents and spontaneous firing in hippocampal CA1 interneurons.
Topics: Amines; Analysis of Variance; Animals; CA1 Region, Hippocampal; Cyclohexanecarboxylic Acids; Electrophysiology; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Interneurons; Male; Membrane Potentials; Rats; Rats, Long-Evans; Synaptic Transmission | 2011 |
[Pitfalls in the treatment of neuropathic pain in patients with cancer].
Topics: Aged; Amines; Amitriptyline; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neoplasms; Neuralgia; Postural Balance; Sensation Disorders | 2011 |
The effects of intrathecal and systemic gabapentin on spinal substance P release.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Injections, Spinal; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P | 2011 |
Analysis of gabapentin in equine plasma with measurement uncertainty estimation by liquid chromatography-tandem mass spectrometry.
Topics: Amines; Animals; Anticonvulsants; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Horses; Particle Size; Tandem Mass Spectrometry | 2011 |
A 10-year-old boy with severe pain in the toes. Diagnosis: erythromelalgia.
Topics: Amines; Analgesics; Child; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Erythromelalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Toes | 2011 |
[Myoclonias secondary to gabapentin in a patient with chronic renal failure].
Topics: Aged; Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Male; Myoclonus | 2011 |
[Determination of gabapentin using capillary electrophoresis with laser-induced fluorescence detection].
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Electrophoresis, Capillary; Gabapentin; gamma-Aminobutyric Acid; Lasers; Spectrometry, Fluorescence | 2010 |
Analgesic effects of tramadol, tramadol-gabapentin, and buprenorphine in an incisional model of pain in rats (Rattus norvegicus).
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Buprenorphine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Models, Animal; Pain, Postoperative; Postoperative Period; Rats; Rats, Sprague-Dawley; Tramadol; Weight-Bearing | 2011 |
Chronic intrathecal infusion of gabapentin prevents nerve ligation-induced pain in rats.
Topics: Amines; Analgesics, Non-Narcotic; Animals; Cauda Equina; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Infusions, Parenteral; Ligation; Male; Pain Measurement; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerves; Weight Gain | 2011 |
Amperometric measurement of glutamate release modulation by gabapentin and pregabalin in rat neocortical slices: role of voltage-sensitive Ca2+ α2δ-1 subunit.
Topics: Amines; Animals; Calcium Channels; Calcium Channels, L-Type; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Mice; Mice, Mutant Strains; Mice, Transgenic; Microelectrodes; Neocortex; Point Mutation; Pregabalin; Rats; Rats, Sprague-Dawley | 2011 |
Incidence of postherpetic neuralgia after combination treatment with gabapentin and valacyclovir in patients with acute herpes zoster: open-label study.
Topics: Acute Disease; Acyclovir; Aged; Amines; Analgesics; Antiviral Agents; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Incidence; Male; Middle Aged; Neuralgia, Postherpetic; Valacyclovir; Valine | 2011 |
[Disease with generalized pain. Guillain-Barré syndrome].
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Humans; Immunization, Passive; Neurologic Examination; Pain; Spasm | 2011 |
Stellate ganglion blockade (SGB) for refractory index finger pain - a case report.
Topics: Abdominal Pain; Accidental Falls; Acetaminophen; Adult; Amines; Autonomic Nerve Block; Chronic Disease; Codeine; Cyclohexanecarboxylic Acids; Dyspareunia; Edema; Electric Stimulation Therapy; Electrodes, Implanted; Female; Finger Injuries; Fingers; Gabapentin; gamma-Aminobutyric Acid; Humans; Immobilization; Morphine; Reflex Sympathetic Dystrophy; Spinal Cord Injuries; Stellate Ganglion; Thoracic Vertebrae; Urinary Retention | 2011 |
Interchangeability of generic anti-epileptic drugs: a quantitative analysis of topiramate and gabapentin.
Topics: Amines; Anticonvulsants; Area Under Curve; Confidence Intervals; Cyclohexanecarboxylic Acids; Drug Interactions; Drugs, Generic; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Risk Factors; Safety; Therapeutic Equivalency; Topiramate | 2011 |
Gabapentin reduces infarct volume but does not suppress peri-infarct depolarizations.
Topics: Amines; Animals; Anticonvulsants; Brain; Brain Infarction; Brain Ischemia; Cortical Spreading Depression; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ischemic Attack, Transient; Male; Mice; Mice, Inbred C57BL | 2011 |
Painful traumatic neuroma of the tongue treated with serial alcohol injections.
Topics: Aged; Amines; Analgesics; Anesthetics, Local; Central Nervous System Depressants; Cyclohexanecarboxylic Acids; Ethanol; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intralesional; Lidocaine; Neoplasm Recurrence, Local; Neuroma; Pain; Tongue Neoplasms | 2011 |
A priori performance prediction in pharmaceutical wet granulation: testing the applicability of the nucleation regime map to a formulation with a broad size distribution and dry binder addition.
Topics: Amines; Anticonvulsants; Cellulose; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Drug Compounding; Drug Design; Excipients; Gabapentin; gamma-Aminobutyric Acid; Molecular Structure; Molecular Weight | 2011 |
Effects of antiepileptic drugs on GABA release from rat and human neocortical synaptosomes.
Topics: Adolescent; Adult; Aged; Amines; Animals; Anticonvulsants; Calcium; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Neocortex; Nipecotic Acids; Oximes; Phenytoin; Piracetam; Potassium; Pregabalin; Rats; Rats, Wistar; Synaptosomes; Tetanus Toxin; Tetrodotoxin; Triazines; Valproic Acid; Veratridine; Young Adult | 2011 |
[An algorithm for postoperative pain management in visceral and thoracic surgery: an observational study].
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Algorithms; Amines; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Digestive System Surgical Procedures; Dipyrone; Etoricoxib; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Hernia, Inguinal; Humans; Inservice Training; Ketamine; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Pirinitramide; Pyridines; Quality Assurance, Health Care; Sulfones; Thoracic Surgery, Video-Assisted; Thoracic Surgical Procedures; Treatment Outcome; Young Adult | 2013 |
FDA approves gabapentin prodrug as restless legs treatment.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Approval; Gabapentin; gamma-Aminobutyric Acid; Humans; United States; United States Food and Drug Administration | 2011 |
Part 2: Design, synthesis and evaluation of hydroxyproline-derived α2δ ligands.
Topics: Amines; Animals; Cells, Cultured; Cyclohexanecarboxylic Acids; Dogs; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydroxyproline; Ligands; Molecular Structure; Protein Subunits; Rats | 2011 |
Suicide by gabapentin overdose.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Depressive Disorder, Major; Drug Overdose; Female; Forensic Toxicology; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Suicide | 2011 |
Characteristic structural parameters for the γ-peptide 14-helix: importance of subunit preorganization.
Topics: Amines; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen Bonding; Peptides; Protein Structure, Secondary | 2011 |
Dose-dependent opposite effects of gabapentin on the depressive action of morphine on a C-fibre reflex in the rat.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Electric Stimulation; Gabapentin; gamma-Aminobutyric Acid; Long-Term Synaptic Depression; Male; Morphine; Nerve Fibers, Unmyelinated; Rats; Rats, Sprague-Dawley; Reflex | 2011 |
Neuroprotective effects of gabapentin on spinal cord ischemia-reperfusion injury in rabbits.
Topics: Amines; Animals; Caspase 3; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Glutathione; Immunohistochemistry; Injections, Intraperitoneal; Male; Malondialdehyde; Nerve Tissue Proteins; Nervous System; Neuroprotective Agents; Nitric Oxide; Oxidation-Reduction; Rabbits; Reperfusion Injury; Spinal Cord; Superoxide Dismutase; Treatment Outcome | 2011 |
Anorgasmia with gabapentin may be common in older patients.
Topics: Age Factors; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Orgasm; Sexual Dysfunction, Physiological | 2011 |
Gabapentin-induced sexual dysfunction.
Topics: Adult; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Depression; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Sexual Dysfunction, Physiological | 2011 |
Resident and fellow section. Teaching case: symptomatic SUNCT.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Education, Medical, Continuing; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Middle Aged; SUNCT Syndrome | 2011 |
The median effective dose of ketamine and gabapentin in opioid-induced hyperalgesia in rats: an isobolographic analysis of their interaction.
Topics: Amines; Analgesics; Analgesics, Opioid; Analysis of Variance; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Intraperitoneal; Injections, Subcutaneous; Ketamine; Male; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Time Factors | 2011 |
Possible heart failure associated with pregabalin use: case report.
Topics: Amines; Analgesics; Back Pain; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Edema; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Failure; Humans; Middle Aged; Neuralgia; Pregabalin; Tramadol | 2011 |
The effects of gabapentin in two animal models of co-morbid anxiety and visceral hypersensitivity.
Topics: Amines; Animals; Anxiety; Comorbidity; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Intestine, Large; Male; Rats; Visceral Pain | 2011 |
Akathisia induced by gabapentin withdrawal.
Topics: Aged; Akathisia, Drug-Induced; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Substance Withdrawal Syndrome | 2011 |
Performance characteristics of the ARK diagnostics gabapentin immunoassay.
Topics: Amines; Anticonvulsants; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunoassay; Seizures; Tandem Mass Spectrometry | 2011 |
Highly sensitive determination and validation of gabapentin in pharmaceutical preparations by HPLC with 4-fluoro-7-nitrobenzofurazan derivatization and fluorescence detection.
Topics: 4-Chloro-7-nitrobenzofurazan; Amines; Capsules; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Linear Models; Mexiletine; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence | 2011 |
Replacement of gabapentin with pregabalin in postherpetic neuralgia therapy.
Topics: Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain Measurement; Pregabalin; Treatment Outcome | 2011 |
Off-label prescribing explained. Why your doctor may recommend meds that aren't FDA-approved for your condition.
Topics: Amines; Bipolar Disorder; Clinical Protocols; Cyclohexanecarboxylic Acids; Drug Approval; Drug Labeling; Gabapentin; gamma-Aminobutyric Acid; Humans; Migraine Disorders; Off-Label Use; Pain; Practice Patterns, Physicians'; Prescription Drugs; Restless Legs Syndrome; United States; United States Food and Drug Administration | 2011 |
Neuritis ossificans of the tibial, common peroneal and lateral sural cutaneous nerves.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Neuritis; Ossification, Heterotopic; Oxycodone; Peripheral Nervous System Diseases; Peroneal Nerve; Sural Nerve; Tibial Nerve; Young Adult | 2011 |
Study of neurontin: titrate to effect, profile of safety (STEPS) trial: a narrative account of a gabapentin seeding trial.
Topics: Amines; Clinical Trials as Topic; Conflict of Interest; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Marketing | 2011 |
Seeding trials and the subordination of science.
Topics: Amines; Anticonvulsants; Clinical Trials as Topic; Conflict of Interest; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans | 2011 |
An in vitro model for testing drugs to treat tinnitus.
Topics: Amines; Animals; Antioxidants; Calcium Channel Blockers; Carnitine; Convulsants; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; Indoles; Mice; Neurons; Pentylenetetrazole; Potassium Channel Blockers; Pregabalin; Pyridines; Tinnitus | 2011 |
Adapting treatment to patient problems.
Topics: Alcoholism; Amines; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Naltrexone; Research Design; Sertraline | 2011 |
Beneficial response to gabapentin portraying with interval change of brain SPECT imaging in a case with failed back surgery syndrome.
Topics: Adult; Amines; Analgesics; Cerebral Cortex; Cerebrovascular Circulation; Cyclohexanecarboxylic Acids; Failed Back Surgery Syndrome; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Regional Blood Flow; Spondylolysis; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2011 |
Urine drug testing of chronic pain patients. IV. prevalence of gabapentin and pregabalin.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Patient Compliance; Pregabalin | 2011 |
Pulsed radiofrequency modulation for lingual neuralgia.
Topics: Amines; Carbamazepine; Cranial Nerve Diseases; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lingual Nerve; Middle Aged; Neuralgia; Oxcarbazepine; Pain Measurement; Pulsed Radiofrequency Treatment; Tongue | 2012 |
The stabilizing effect of moisture on the solid-state degradation of gabapentin.
Topics: Amines; Anticonvulsants; Aza Compounds; Chromatography, Reverse-Phase; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Humidity; Particle Size; Powders; Spectroscopy, Fourier Transform Infrared; Spiro Compounds; Surface Properties; Technology, Pharmaceutical; Water; X-Ray Diffraction | 2011 |
Stiff person syndrome and pregnancy.
Topics: Adult; Amines; Baclofen; Cesarean Section; Cyclohexanecarboxylic Acids; Diazepam; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Muscle Relaxants, Central; Prednisone; Pregnancy; Spasm; Stiff-Person Syndrome; Treatment Outcome | 2011 |
Treatment of Harlequin syndrome by costotransversectomy and sympathectomy: case report.
Topics: Adult; Amines; Analgesics; Autonomic Nervous System Diseases; Cyclohexanecarboxylic Acids; Female; Flushing; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypohidrosis; Magnetic Resonance Imaging; Pain, Postoperative; Sympathectomy; Thoracotomy | 2011 |
Chronic Lyme disease: the controversies and the science.
Topics: Amines; Analgesics; Anti-Bacterial Agents; Arthritis, Rheumatoid; Borrelia burgdorferi; Chronic Disease; Contraindications; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Gabapentin; gamma-Aminobutyric Acid; Humans; Lyme Disease; Neurodegenerative Diseases; Pain; Pain Management; Practice Guidelines as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Syndrome | 2011 |
Gabapentin as part of multi-modal analgesia in two cats suffering multiple injuries.
Topics: Amines; Analgesia; Analgesics; Animals; Buprenorphine; Cat Diseases; Cats; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Injections, Intravenous; Male; Methadone; Multiple Trauma; Pain; Pain Measurement | 2011 |
Manual acupuncture inhibits mechanical hypersensitivity induced by spinal nerve ligation in rats.
Topics: Acupuncture Points; Acupuncture Therapy; Amines; Analgesics; Analysis of Variance; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Ligation; Male; Musculoskeletal Manipulations; Naloxone; Narcotic Antagonists; Neuralgia; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Spinal Nerves; Time Factors | 2011 |
Prevent rather than treat postherpetic neuralgia by prescribing gabapentin earlier in patients with herpes zoster: comment on "incidence of postherpetic neuralgia after combination treatment with gabapentin and valacyclovir in patients with acute herpes z
Topics: Acyclovir; Amines; Analgesics; Antiviral Agents; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Male; Neuralgia, Postherpetic; Valacyclovir; Valine | 2011 |
Cost analysis of adding pregabalin or gabapentin to the management of community-treated patients with peripheral neuropathic pain.
Topics: Aged; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Comorbidity; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Health Services; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Pregabalin; Retrospective Studies; Socioeconomic Factors | 2012 |
Astrocytes promote peripheral nerve injury-induced reactive synaptogenesis in the neonatal CNS.
Topics: Age Factors; Aldehyde Dehydrogenase 1 Family; Amines; Animals; Animals, Newborn; Astrocytes; Biophysics; Cell Differentiation; Chondroitin Sulfate Proteoglycans; Critical Period, Psychological; Cyclohexanecarboxylic Acids; Denervation; Disease Models, Animal; Electron Transport Complex IV; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluoroacetates; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Retinal Dehydrogenase; Synapses; Synaptophysin; Time Factors; Trigeminal Nerve Injuries; Trigeminal Nuclei; Vibrissae | 2011 |
Successful amelioration of tinnitus in a stroke patient by low-dose gabapentin.
Topics: Amines; Audiometry, Pure-Tone; Basal Ganglia Hemorrhage; Cerebral Angiography; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hearing Loss, Mixed Conductive-Sensorineural; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Stroke; Tinnitus; Tomography, X-Ray Computed; Treatment Outcome | 2012 |
Accounting for perception, placebo and unmasking effects in estimating treatment effects in randomised clinical trials.
Topics: Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain; Placebo Effect; Placebos; Randomized Controlled Trials as Topic; Research Design | 2014 |
Pharmacological and behavioral characterization of the saphenous chronic constriction injury model of neuropathic pain in rats.
Topics: Amines; Amitriptyline; Analgesics; Animals; Benzoxazines; Chronic Disease; Constriction; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Ligation; Male; Morphine; Morpholines; Naphthalenes; Neuralgia; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Wistar; Time Factors | 2011 |
[Effects of gabapentin on high-voltage-activated calcium current in dorsal root ganglion neurons in rats].
Topics: Amines; Animals; Calcium Channels, N-Type; Cells, Cultured; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 2011 |
[Clinical characteristics and treatment for new onset epilepsy in the elderly].
Topics: Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diagnostic Imaging; Electroencephalography; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Patient Education as Topic; Piracetam; Social Support; Triazines | 2010 |
Interactions of pregabalin with gabapentin, levetiracetam, tiagabine and vigabatrin in the mouse maximal electroshock-induced seizure model: a type II isobolographic analysis.
Topics: Amines; Animals; Anticonvulsants; Avoidance Learning; Confidence Intervals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Levetiracetam; Male; Mice; Motor Activity; Piracetam; Pregabalin; Seizures; Vigabatrin | 2012 |
Quiz Page October 2011: An under-recognized cause of CKD.
Topics: Acidosis; Amines; Anorexia Nervosa; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Creatinine; Cyclohexanecarboxylic Acids; False Negative Reactions; Female; Fluid Therapy; Gabapentin; gamma-Aminobutyric Acid; Glomerulosclerosis, Focal Segmental; Humans; Hypokalemia; Kidney Cortex; Middle Aged; Naproxen; Nephritis, Interstitial; Potassium; Vacuoles | 2011 |
Off-label gabapentin masking ictal triphasic waves: case analysis of neuropsychiatric and electrographic correlates.
Topics: Administration, Oral; Aged; Amines; Anticonvulsants; Brain Waves; Cyclohexanecarboxylic Acids; Electroencephalography; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Levetiracetam; Piracetam; Psychotic Disorders | 2011 |
Rewarding electrical brain stimulation in rats after peripheral nerve injury: decreased facilitation by commonly abused prescription opioids.
Topics: Adenosine; Amines; Analgesics; Analgesics, Opioid; Animals; Brain; Clonidine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electric Stimulation; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Hydromorphone; Injections, Spinal; Male; Methadone; Oxycodone; Peripheral Nerve Injuries; Rats; Rats, Inbred F344; Reward | 2011 |
Pharmacological tests of hypotheses for acquired pendular nystagmus.
Topics: Amines; Baclofen; Cerebellar Cortex; Cyclohexanecarboxylic Acids; Eye Movements; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Models, Neurological; Multiple Sclerosis; Myoclonus; Nystagmus, Pathologic; Olivary Nucleus | 2011 |
Successful treatment of tabetic lightning pain and visceral crisis with gabapentin.
Topics: Amines; Cyclohexanecarboxylic Acids; Extremities; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Management; Tabes Dorsalis | 2011 |
Comparison of two aerosol-based detectors for the analysis of gabapentin in pharmaceutical formulations by hydrophilic interaction chromatography.
Topics: Aerosols; Amines; Analgesics; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Limit of Detection; Pharmaceutical Preparations; Reproducibility of Results | 2011 |
Retention rate of Gabapentin in children with intractable epilepsies at 1 year.
Topics: Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Male | 2012 |
[Efficacy and tolerability of dose-escalation with generic gabapentin--a multicenter, non-interventional study].
Topics: Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Disorders of Excessive Somnolence; Dizziness; Dose-Response Relationship, Drug; Drugs, Generic; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome | 2011 |
Role of gabapentin in preventing fentanyl- and morphine-withdrawal-induced hyperalgesia in rats.
Topics: Amines; Analgesics, Opioid; Animals; Chronic Pain; Cyclohexanecarboxylic Acids; Drug Tolerance; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Morphine; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2012 |
Prescription pattern of oral healthcare professionals in the use of anticonvulsants for trigeminal neuralgia.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Combinations; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Practice Patterns, Dentists'; Topiramate; Trigeminal Neuralgia | 2008 |
Economic evaluation of duloxetine as a first-line treatment for painful diabetic peripheral neuropathy in Mexico.
Topics: Amines; Analgesics; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Dopamine Uptake Inhibitors; Drug Costs; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Humans; Mexico; Pregabalin; Thiophenes | 2012 |
Persistent hiccup after surgical resection of a brainstem arteriovenous malformation: a case successfully treated with gabapentin during rehabilitation. Case report.
Topics: Administration, Oral; Amines; Arteriovenous Fistula; Brain Stem; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Intracranial Arteriovenous Malformations; Male; Neurosurgical Procedures; Young Adult | 2012 |
Once-daily gabapentin (Gralise) for postherpetic neuralgia.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia, Postherpetic | 2011 |
Pathophysiology of freezing of gait and some possible treatments for it.
Topics: Amines; Cyclohexanecarboxylic Acids; Dopamine; Excitatory Amino Acid Antagonists; Gabapentin; Gait; Gait Disorders, Neurologic; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Models, Theoretical; Neural Networks, Computer; Parkinson Disease | 2012 |
Pharmacological interaction between gabapentin and glibenclamide in the formalin test in the diabetic rat.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Glyburide; KATP Channels; Male; Pain Measurement; Rats; Rats, Wistar | 2010 |
Gabapentin in the treatment of dementia-associated nocturnal agitation.
Topics: Aged; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Darkness; Dementia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Psychomotor Agitation | 2011 |
Risk of cancer in patients exposed to gabapentin in two electronic medical record systems.
Topics: Aged; Aged, 80 and over; Amines; Anticonvulsants; California; Case-Control Studies; Cohort Studies; Cyclohexanecarboxylic Acids; Databases, Factual; Electronic Health Records; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Logistic Models; Male; Middle Aged; Neoplasms; Risk; United Kingdom; United States | 2012 |
False Claims Act prosecution did not deter off-label drug use in the case of neurontin.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Industry; Gabapentin; gamma-Aminobutyric Acid; Humans; Liability, Legal; Marketing; Off-Label Use; United States; United States Food and Drug Administration | 2011 |
Possible GABAergic mechanism in the neuroprotective effect of gabapentin and lamotrigine against 3-nitropropionic acid induced neurotoxicity.
Topics: Amines; Animals; Body Weight; Brain; Catalase; Cyclohexanecarboxylic Acids; GABAergic Neurons; Gabapentin; gamma-Aminobutyric Acid; Huntington Disease; Lamotrigine; Lipid Peroxidation; Locomotion; Male; Mitochondria; Neuroprotective Agents; Neurotoxins; Nitrites; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Wistar; Rotarod Performance Test; Superoxide Dismutase; Triazines; Tumor Necrosis Factor-alpha | 2012 |
Primary erythromelalgia in a 12-year-old boy: positive response to sodium channel blockers despite negative SCN9A mutations.
Topics: Administration, Oral; Amines; Analgesics; Child; Cyclohexanecarboxylic Acids; Diagnosis, Differential; DNA Mutational Analysis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythromelalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusions, Intravenous; Lidocaine; Male; Mexiletine; NAV1.7 Voltage-Gated Sodium Channel; Nitroprusside; Sodium Channel Blockers; Treatment Outcome; Vasodilator Agents | 2012 |
Use of single- and multi-drug regimens in the management of classic (idiopathic) trigeminal neuralgia: an 11-year experience at a single Sri Lankan institution.
Topics: Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Pain Measurement; Phenytoin; Retrospective Studies; Sri Lanka; Treatment Outcome; Trigeminal Neuralgia; Valproic Acid | 2012 |
Costs of pregabalin or gabapentin for painful diabetic peripheral neuropathy.
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Databases, Factual; Diabetic Nephropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Health Resources; Humans; Male; Middle Aged; Pain; Pregabalin; Prescription Fees; Retrospective Studies; United States | 2012 |
Impact of ventralis caudalis deep brain stimulation combined with stereotactic bilateral cingulotomy for treatment of post-stroke pain.
Topics: Amines; Analgesics; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Deep Brain Stimulation; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Pain, Intractable; Radiosurgery; Retrospective Studies; Stroke; Treatment Outcome | 2012 |
Riluzole and gabapentinoids activate glutamate transporters to facilitate glutamate-induced glutamate release from cultured astrocytes.
Topics: Amines; Amino Acid Transport System X-AG; Animals; Astrocytes; Biological Transport; Calcium; Cells, Cultured; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Intracellular Space; Ligands; Protein Subunits; Rats; Riluzole; Sodium | 2012 |
Biphasic effects of chronic intrathecal gabapentin administration on the expression of protein kinase C gamma in the spinal cord of neuropathic pain rats.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Neuralgia; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spinal Cord | 2011 |
[Multiple mononeuritis and eosinophilic fasciitis in a patient with idiopathic hypereosinophilic syndrome].
Topics: Adrenal Cortex Hormones; Adult; Amines; Cyclohexanecarboxylic Acids; Eosinophilia; Excitatory Amino Acid Antagonists; Fasciitis; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypereosinophilic Syndrome; Mononeuropathies | 2012 |
Effects of intraperitoneal administration of gabapentin on the minimum alveolar concentration of isoflurane in adult male rats.
Topics: Amines; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Isoflurane; Male; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley | 2012 |
[LC-MS/MS method for quantification and pharmacokinetic study of gabapentin in human plasma].
Topics: Administration, Oral; Amines; Anticonvulsants; Area Under Curve; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2011 |
Therapy-resistant opsoclonus-myoclonus syndrome secondary to HIV-1 infection.
Topics: Adult; Amines; Anti-HIV Agents; Anti-Inflammatory Agents; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; HIV Infections; HIV-1; Humans; Immunoglobulins, Intravenous; Opsoclonus-Myoclonus Syndrome; Prednisolone; RNA, Viral; Treatment Failure | 2012 |
Unusual case of a swollen painful toe in a young man.
Topics: Acne Vulgaris; Adult; Amines; Analgesics, Opioid; Anti-Bacterial Agents; Arthritis; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Doxycycline; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Gonorrhea; Hallux; Humans; Lidocaine; Lyme Disease; Magnetic Resonance Imaging; Male; Neuritis; Syphilis; Tramadol; Treatment Outcome | 2012 |
Peripheral neuropathy response to erythropoietin in type 2 diabetic patients with mild to moderate renal failure.
Topics: Aged; Aged, 80 and over; Amines; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Drug Therapy, Combination; Erythropoietin; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neural Conduction; Neurologic Examination; Peripheral Nervous System Diseases; Peroneal Nerve; Recombinant Proteins; Renal Insufficiency; Sural Nerve; Surveys and Questionnaires; Tibial Nerve | 2012 |
Subdural hematoma after an epidural blood patch.
Topics: Acetaminophen; Adult; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents; Blood Patch, Epidural; Cauda Equina; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Hematoma, Subdural, Spinal; Humans; Hydrocodone; Magnetic Resonance Imaging; Methylprednisolone; Post-Dural Puncture Headache; Prednisone; Pregnancy; Puerperal Disorders; Spinal Stenosis; Treatment Outcome | 2012 |
Evaluation of anxiolytic effect and withdrawal anxiety in chronic intermittent diazepam treatment in rats.
Topics: Amines; Animals; Anti-Anxiety Agents; Anxiety; Cyclohexanecarboxylic Acids; Diazepam; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Grooming; Male; Maze Learning; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 2012 |
Reversible delirium in an advanced cancer patient.
Topics: Amines; Analgesics; Analgesics, Opioid; Bone Neoplasms; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Lobular; Cyclohexanecarboxylic Acids; Delirium; Disease Progression; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lorazepam; Midazolam; Middle Aged; Neoplasm Staging; Neoplasms, Multiple Primary; Palliative Care; Spinal Neoplasms | 2012 |
Peripheral nerve toxic effects of nitrofurantoin.
Topics: Amines; Analgesics; Anti-Infective Agents, Urinary; Biopsy; Cyclohexanecarboxylic Acids; Cystitis, Interstitial; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Nerve Fibers; Neurologic Examination; Nitrofurantoin; Paresthesia; Perineum; Peripheral Nervous System Diseases; Psoriasis; Skin; Thiophenes; Treatment Outcome; Urinary Tract Infections | 2012 |
Assessing carrageenan-induced locomotor activity impairment in rats: comparison with evoked endpoint of acute inflammatory pain.
Topics: Acute Pain; Adrenergic Uptake Inhibitors; Amines; Amphetamine; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Carrageenan; Central Nervous System Stimulants; Cyclohexanecarboxylic Acids; Diclofenac; Disease Models, Animal; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Ibuprofen; Lameness, Animal; Male; Morphine; Motor Activity; Neuritis; Rats; Rats, Sprague-Dawley; Thiophenes | 2012 |
Pharmacological characterization of lysophosphatidic acid-induced pain with clinically relevant neuropathic pain drugs.
Topics: Amines; Analgesics; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Indomethacin; Lysophospholipids; Male; Mice; Morphine; Motor Activity; Neuralgia; Neurons; Pregabalin; Spinal Cord | 2012 |
Analgesic effect of gabapentin in a rat model for chronic constrictive injury.
Topics: Amines; Analgesics; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Neuralgia; Rats; Rats, Sprague-Dawley | 2011 |
Pemetrexed-induced cellulitis: a rare toxicity in non-small cell lung cancer treatment.
Topics: Adrenal Cortex Hormones; Aged; Amines; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Cellulitis; Cyclohexanecarboxylic Acids; Drug Monitoring; Drug Resistance, Neoplasm; Excitatory Amino Acid Antagonists; Female; Folic Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamates; Guanine; Humans; Lower Extremity; Lung Neoplasms; Neurotoxicity Syndromes; Pemetrexed; Peripheral Nervous System Diseases; Treatment Outcome | 2013 |
The combined predictive capacity of rat models of algogen-induced and neuropathic hypersensitivity to clinically used analgesics varies with nociceptive endpoint and consideration of locomotor function.
Topics: Amines; Analgesics; Animals; Capsaicin; Cyclohexanecarboxylic Acids; Disease Models, Animal; Duloxetine Hydrochloride; Exploratory Behavior; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Locomotion; Male; Morphine; Neuralgia; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Thiophenes | 2012 |
Influence of carvedilol on anticonvulsant effect of gabapentin.
Topics: Amines; Analysis of Variance; Animals; Anticonvulsants; Brain; Carbazoles; Carvedilol; Convulsants; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electroshock; Exploratory Behavior; Gabapentin; gamma-Aminobutyric Acid; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Memory; Mice; Motor Activity; Pentylenetetrazole; Propanolamines; Rotarod Performance Test; Seizures; Vasodilator Agents | 2011 |
Pharmacokinetics and milk secretion of gabapentin and meloxicam co-administered orally in Holstein-Friesian cows.
Topics: Administration, Oral; Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Meloxicam; Milk; Thiazines; Thiazoles | 2013 |
What does the future hold for patients with epilepsy?
Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Oxcarbazepine; Topiramate; Triazines | 2012 |
Animal behavior case of the month. Motivation for the tail-chasing behavior was considered to most likely be multifactorial.
Topics: Acepromazine; Amines; Animals; Anticonvulsants; Behavior, Animal; Compulsive Behavior; Cyclohexanecarboxylic Acids; Displacement, Psychological; Dog Diseases; Dogs; Dopamine Antagonists; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Selective Serotonin Reuptake Inhibitors | 2012 |
Spontaneous burrowing behaviour in the rat is reduced by peripheral nerve injury or inflammation associated pain.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cyclohexanecarboxylic Acids; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Ibuprofen; Inflammation; Pain; Pain Measurement; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Social Environment; Spinal Nerves; Tibial Nerve | 2012 |
Protective effects of combined therapy of gliclazide with curcumin in experimental diabetic neuropathy in rats.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; C-Peptide; Curcumin; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Gliclazide; Hyperalgesia; Hypoglycemic Agents; Lipid Peroxides; Male; Pain Threshold; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2012 |
The efficacy of morphine, pregabalin, gabapentin, and duloxetine on mechanical allodynia is different from that on neuroma pain in the rat neuropathic pain model.
Topics: Administration, Oral; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Morphine; Neuralgia; Neuroma; Pain Measurement; Pain Threshold; Pregabalin; Rats; Rats, Sprague-Dawley; Thiophenes; Time Factors | 2012 |
Do carbamazepine, gabapentin, or other anticonvulsants exert sufficient radioprotective effects to alter responses from trigeminal neuralgia radiosurgery?
Topics: Adult; Aged; Aged, 80 and over; Amines; Analysis of Variance; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Radiation-Protective Agents; Radiosurgery; Radiotherapy Dosage; Retrospective Studies; Trigeminal Neuralgia | 2012 |
Gabapentin inhibits catecholamine release from adrenal chromaffin cells.
Topics: Adrenal Glands; Amines; Animals; Calcium; Calcium Channels; Calcium Signaling; Catecholamines; Cattle; Cholinergic Agonists; Chromaffin Cells; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hemodynamics; In Vitro Techniques; Patch-Clamp Techniques; Potassium Chloride; Secretory Vesicles | 2012 |
Kinetic model for solid-state degradation of gabapentin.
Topics: Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrolysis; Kinetics; Models, Theoretical; Powder Diffraction | 2012 |
Statement of the AGNP in the Context of the Planned Formation of a Fixed Reference Price Group "GABA-Analogues", November 21, 2011.
Topics: Amines; Anti-Anxiety Agents; Anxiety Disorders; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Germany; Humans; Insurance Coverage; Insurance, Health, Reimbursement; Pregabalin; Societies, Scientific | 2012 |
Plexiform neurofibroma in an 8 year-old patient.
Topics: Amines; Analgesics; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Neurofibroma, Plexiform; Neurofibromatosis 1; Neuropsychological Tests; Peripheral Nervous System Neoplasms; Sciatic Neuropathy | 2013 |
Spinal mechanism underlying the antiallodynic effect of gabapentin studied in the mouse spinal nerve ligation model.
Topics: Amines; Analgesics; Animals; Calcium Channels; CD11b Antigen; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Spinal; Ligation; Male; Mice; Mice, Inbred C57BL; Neuralgia; Spinal Nerves; Treatment Outcome | 2012 |
Need for improved treatment of postoperative pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Denmark; Female; Gabapentin; gamma-Aminobutyric Acid; Health Services Needs and Demand; Humans; Internationality; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Quality of Health Care; Young Adult | 2012 |
Gabapentin augments the antihyperalgesic effects of diclofenac sodium through spinal action in a rat postoperative pain model.
Topics: Amines; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Diclofenac; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Spinal; Neural Pathways; Pain Measurement; Pain Threshold; Pain, Postoperative; Rats; Spinal Cord; Time Factors | 2012 |
Endpoints of drug discovery for menopausal vasomotor symptoms: interpretation of data from a proxy of disease.
Topics: Acetamides; Amines; Animals; Body Temperature Regulation; Cyclohexanecarboxylic Acids; Cyclohexanols; Disease Models, Animal; Diurnal Enuresis; Drug Discovery; Estradiol; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Hypnotics and Sedatives; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Skin Temperature; Venlafaxine Hydrochloride | 2012 |
Pain alleviation and patient-reported health outcomes following switching to pregabalin in individuals with gabapentin-refractory neuropathic pain in routine medical practice.
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pregabalin; Quality of Life; Surveys and Questionnaires; Treatment Outcome | 2012 |
Evaluation of aqueous and ethanolic extracts of saffron, Crocus sativus L., and its constituents, safranal and crocin in allodynia and hyperalgesia induced by chronic constriction injury model of neuropathic pain in rats.
Topics: Acetone; Amines; Analgesics; Animals; Behavior, Animal; Carotenoids; Constriction; Crocus; Cyclohexanecarboxylic Acids; Cyclohexenes; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Male; Neuralgia; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Terpenes; Walking | 2012 |
Gabapentin inhibits γ-amino butyric acid release in the locus coeruleus but not in the spinal dorsal horn after peripheral nerve injury in rats.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Extracellular Space; Gabapentin; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunohistochemistry; Ligation; Locus Coeruleus; Male; Microdialysis; Peripheral Nerve Injuries; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Spinal Nerves; Synaptosomes | 2012 |
Nighttime awakenings responding to gabapentin therapy in late premenopausal women: a case series.
Topics: Adult; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Estradiol; Female; Follicle Stimulating Hormone; Gabapentin; gamma-Aminobutyric Acid; Humans; Luteinizing Hormone; Middle Aged; Premenopause; Sleep Initiation and Maintenance Disorders; Sweating | 2012 |
The effects of gabapentin on acute opioid tolerance to remifentanil under sevoflurane anesthesia in rats.
Topics: Adjuvants, Anesthesia; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, Inhalation; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Methyl Ethers; Pain Threshold; Piperidines; Rats; Rats, Wistar; Remifentanil; Sevoflurane; Time Factors | 2012 |
Does Pregabalin (Lyrica(®) ) help patients reduce their use of benzodiazepines? A comparison with gabapentin using the Norwegian Prescription Database.
Topics: Adolescent; Adult; Amines; Anti-Anxiety Agents; Benzodiazepines; Cyclohexanecarboxylic Acids; Databases, Factual; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization Review; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Norway; Pregabalin; Young Adult | 2010 |
Low-dose gabapentin for intractable hiccups in a heart transplant recipient.
Topics: Adult; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Heart Transplantation; Hiccup; Humans; Male | 2011 |
α2δ ligands act as positive modulators of adult hippocampal neurogenesis and prevent depression-like behavior induced by chronic restraint stress.
Topics: Amines; Animals; Calcium Channels; Cell Differentiation; Cyclohexanecarboxylic Acids; Depression; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Ligands; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Pregabalin; Random Allocation; Restraint, Physical; Stress, Psychological | 2012 |
Temperature-dependent enhancement of the antinociceptive effects of opioids in combination with gabapentin in mice.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Male; Mice; Morphine; Oxycodone; Pain; Pain Measurement | 2012 |
Costs, work absence, and adherence in patients with partial onset seizures prescribed gabapentin or pregabalin.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Cohort Studies; Cyclohexanecarboxylic Acids; Databases, Factual; Drug Costs; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Health Expenditures; Humans; Male; Middle Aged; Patient Compliance; Pregabalin; Sick Leave; Workers' Compensation; Young Adult | 2012 |
Gabapentin reduces CX3CL1 signaling and blocks spinal microglial activation in monoarthritic rats.
Topics: Amines; Animals; Arthritis; Calcium Channels, L-Type; Chemokine CX3CL1; CX3C Chemokine Receptor 1; Cyclohexanecarboxylic Acids; Disease Models, Animal; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Intra-Articular; Injections, Intraperitoneal; Lumbar Vertebrae; Male; Microglia; Models, Biological; Pain; Posterior Horn Cells; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, Chemokine; Signal Transduction; Spinal Cord; Time Factors | 2012 |
Study of emotional and cognitive impairments in mononeuropathic rats: effect of duloxetine and gabapentin.
Topics: Affective Symptoms; Amines; Analgesics; Animals; Antidepressive Agents; Cognition; Cognition Disorders; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Duloxetine Hydrochloride; Emotions; Gabapentin; gamma-Aminobutyric Acid; Male; Neuralgia; Rats; Rats, Sprague-Dawley; Thiophenes; Treatment Outcome | 2012 |
[Efficacy of convalis in the treatment of pain diabetic polyneuropathy and it's influence on biological age].
Topics: Adult; Age Factors; Aging; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Treatment Outcome | 2012 |
Sildenafil influences the anticonvulsant activity of vigabatrin and gabapentin in the timed pentylenetetrazole infusion test in mice.
Topics: Amines; Animals; Anticonvulsants; Avoidance Learning; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hand Strength; Male; Mice; Motor Skills; Pentylenetetrazole; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Seizures; Sildenafil Citrate; Sulfones; Vigabatrin | 2012 |
Lack of behavioral and cognitive effects of chronic ethosuximide and gabapentin treatment in the Ts65Dn mouse model of Down syndrome.
Topics: Amines; Animals; Anticonvulsants; Behavior, Animal; Cognition; Cyclohexanecarboxylic Acids; Disease Models, Animal; Down Syndrome; Ethosuximide; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Gabapentin; gamma-Aminobutyric Acid; Male; Mice | 2012 |
Newer anticonvulsants: lamotrigine, topiramate and gabapentin.
Topics: Abnormalities, Drug-Induced; Adult; Amines; Anticonvulsants; Case-Control Studies; Child; Child, Preschool; Cleft Palate; Cognition; Cohort Studies; Cyclohexanecarboxylic Acids; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Gestational Age; Humans; Infant; Infant, Newborn; Lamotrigine; Learning; Maternal Exposure; Pregnancy; Registries; Risk; Topiramate; Triazines | 2012 |
Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of type I diabetes.
Topics: Amines; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Drug Design; Fatty Acids; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hyperalgesia; Insulin; Lipids; Male; Models, Chemical; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord | 2012 |
[Brachioradial pruritus effectively treated with gabapentin].
Topics: Amines; Antipruritics; Arm; Brachial Plexus Neuropathies; Cervical Vertebrae; Cyclohexanecarboxylic Acids; Female; Forearm; Gabapentin; gamma-Aminobutyric Acid; Humans; Ice; Middle Aged; Polyradiculopathy; Pruritus; Seasons; Sunlight | 2012 |
Electrochemical and spectroscopic studies of the interaction between the neuroleptic drug, gabapentin, and DNA.
Topics: Amines; Antipsychotic Agents; Circular Dichroism; Cyclohexanecarboxylic Acids; DNA; Electrochemical Techniques; Gabapentin; gamma-Aminobutyric Acid; Intercalating Agents; Oxidation-Reduction; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Static Electricity | 2012 |
Non-surgical therapy for bilateral glossopharyngeal neuralgia caused by Eagle's syndrome, diagnosed by three-dimensional computed tomography: a case report.
Topics: Aged; Amines; Analgesics; Anesthetics, Local; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ganglionic Blockers; Glossopharyngeal Nerve Diseases; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Lidocaine; Male; Ossification, Heterotopic; Pain; Pain Measurement; Stellate Ganglion; Temporal Bone; Tomography, X-Ray Computed | 2012 |
Gabapentin decreases epileptiform discharges in a chronic model of neocortical trauma.
Topics: Amines; Animals; Anticonvulsants; Blotting, Western; Brain Injuries; Cyclohexanecarboxylic Acids; Disease Models, Animal; Epilepsy, Post-Traumatic; Gabapentin; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Neocortex; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 2012 |
Orofacial pain due to trigeminal autonomic cephalgia with features of short-lasting neuralgiform headache attacks with conjunctival injection and tearing: a case report.
Topics: Amines; Analgesics; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Diagnostic Imaging; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Sphenoid Sinus; SUNCT Syndrome | 2012 |
Antinociceptive effects of gabapentin & its mechanism of action in experimental animal studies.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dinoprostone; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Humans; Male; Mice; Nitric Oxide Synthase Type I; Pain; Rats; Rats, Sprague-Dawley | 2012 |
Kinetic considerations on the development of binding assays in single-addition mode: application to the search for α2δ1 modulators.
Topics: Amines; Binding, Competitive; Calcium Channels, N-Type; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; HEK293 Cells; High-Throughput Screening Assays; Humans; Kinetics; Ligands; Models, Chemical; Protein Binding; Radioligand Assay; Scintillation Counting | 2012 |
Effect of catalytic alkali metal bromide on Hofmann-type rearrangement of imides.
Topics: Amines; Bromides; Catalysis; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Imides; Metals, Alkali; Oxidation-Reduction | 2012 |
Gabapentin in the treatment of post-dural puncture headache: a case series.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Post-Dural Puncture Headache | 2012 |
Neuropathic truncal pain--a case series.
Topics: Abdominal Pain; Adolescent; Adult; Amines; Analgesics; Anesthetics, Local; Antidepressive Agents; Chest Pain; Cyclohexanecarboxylic Acids; Denervation; Diabetic Neuropathies; Diagnosis, Differential; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Peripheral Nervous System; Torso; Treatment Outcome | 2012 |
Gabapentin and pregabalin: abuse and addiction.
Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Substance Withdrawal Syndrome; Substance-Related Disorders | 2012 |
Chronic postsurgical pain: are we closer to understanding the puzzle?
Topics: Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain, Postoperative; Pregabalin | 2012 |
The amygdala to periaqueductal gray pathway: plastic changes induced by audiogenic kindling and reversal by gabapentin.
Topics: Acoustic Stimulation; Action Potentials; Amines; Amygdala; Animals; Cyclohexanecarboxylic Acids; Electric Stimulation; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Kindling, Neurologic; Neural Pathways; Neuronal Plasticity; Periaqueductal Gray; Rats | 2012 |
Gabapentin for treating acquired neurogenic stuttering.
Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Humans; Stuttering | 2012 |
The antinociceptive effects of systemic administration of tramadol, gabapentin and their combination on mice model of acute pain.
Topics: Acute Pain; Amines; Analgesics; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Nociception; Pain Measurement; Random Allocation; Tramadol | 2012 |
Substance misuse of gabapentin.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Prescription Drug Misuse | 2012 |
Treatment with gabapentin associated with resolution of apnea in two infants with neurologic impairment.
Topics: Amines; Analgesics; Apnea; Central Nervous System; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Muscle Hypertonia; Pain; Treatment Outcome | 2013 |
The impact of gabapentin administration on brain GABA and glutamate concentrations: a 7T ¹H-MRS study.
Topics: Administration, Oral; Adult; Amines; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Young Adult | 2012 |
Implementation of a publication strategy in the context of reporting biases. A case study based on new documents from Neurontin litigation.
Topics: Access to Information; Amines; Analgesics; Antimanic Agents; Authorship; Bipolar Disorder; Clinical Trials as Topic; Conflict of Interest; Correspondence as Topic; Cyclohexanecarboxylic Acids; Documentation; Drug Costs; Drug Industry; Electronic Mail; Evidence-Based Medicine; Fraud; Gabapentin; gamma-Aminobutyric Acid; Humans; Marketing of Health Services; Migraine Disorders; Neuralgia; Nociceptive Pain; Off-Label Use; Periodicals as Topic; Publication Bias | 2012 |
Characterization of nerve growth factor-induced mechanical and thermal hypersensitivity in rats.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Celecoxib; Cyclohexanecarboxylic Acids; Diclofenac; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Nerve Growth Factor; Pain Threshold; Physical Stimulation; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Sulfonamides; Sulfones; Thiophenes; TRPV Cation Channels | 2013 |
Epidural lipomatosis causing new debilitating back pain in a patient with human immunodeficiency virus on highly active antiretroviral therapy.
Topics: Adult; Amines; Analgesics; Analgesics, Opioid; Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Antiretroviral Therapy, Highly Active; Back Pain; Cyclohexanecarboxylic Acids; Delivery, Obstetric; Epidural Space; Female; Fentanyl; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; HIV; HIV Infections; Humans; Lipomatosis; Magnetic Resonance Imaging; Pregnancy; Pregnancy Complications, Infectious; Spinal Diseases | 2012 |
Collagen antibody-induced arthritis evokes persistent pain with spinal glial involvement and transient prostaglandin dependency.
Topics: Amines; Analgesics; Animals; Arthralgia; Arthritis, Experimental; Buprenorphine; Cyclohexanecarboxylic Acids; Diclofenac; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Neuroglia; Prostaglandins; Spine; Time Factors; Treatment Outcome | 2012 |
Gabapentin: a suppressant for refractory chronic cough.
Topics: Amines; Cough; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neurotransmitter Agents | 2012 |
"From safe source to safe sink" development of colorimetric assay for gabapentin in bulk drug and capsules using naturally derived genipin.
Topics: Amines; Biological Products; Capsules; Color; Colorimetry; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hydrogen-Ion Concentration; Indicators and Reagents; Iridoids; Laboratories; Reproducibility of Results; Safety; Time Factors; Waste Management | 2012 |
Patterns of nerve injury and neuropathic pain in ischemic neuropathy after ligation-reperfusion of femoral artery in mice.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Femoral Artery; Gabapentin; gamma-Aminobutyric Acid; Ligation; Male; Mice; Mice, Inbred ICR; Nerve Degeneration; Neural Conduction; Neuralgia; Pain Measurement; Reperfusion Injury | 2012 |
Varicella-zoster virus infection and nummular headache: a possible association with epicranial neuralgia.
Topics: 2-Aminopurine; Amines; Analgesics; Antiviral Agents; Comorbidity; Cyclohexanecarboxylic Acids; Famciclovir; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Herpes Zoster; Herpesvirus 3, Human; Humans; Middle Aged; Neuralgia; Treatment Outcome | 2012 |
The effect of intrathecal gabapentin on neuropathic pain is independent of the integrity of the dorsolateral funiculus in rats.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Neuralgia; Pain Threshold; Rats; Rats, Wistar; Spinal Cord; Spinal Nerves | 2012 |
Positive allosteric modulation of GABA-A receptors reduces capsaicin-induced primary and secondary hypersensitivity in rats.
Topics: Amines; Analgesics, Opioid; Animals; Behavior, Animal; Benzimidazoles; Capsaicin; Cyclohexanecarboxylic Acids; Diazepam; Endpoint Determination; GABA Antagonists; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Pain; Physical Stimulation; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Triazoles | 2012 |
Astrocyte-derived thrombospondins mediate the development of hippocampal presynaptic plasticity in vitro.
Topics: Adenosine; Amines; Animals; Animals, Newborn; Astrocytes; Biophysics; Coculture Techniques; CREB-Binding Protein; Culture Media, Conditioned; Cyclic AMP; Cyclohexanecarboxylic Acids; Dynamin I; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; N-Methylaspartate; Nerve Tissue Proteins; Neuronal Plasticity; Organ Culture Techniques; Patch-Clamp Techniques; Phosphorylation; Potassium Chloride; Presynaptic Terminals; Protein Kinase Inhibitors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Statistics, Nonparametric; Synapses; Thionucleotides; Thrombospondins; Valine; Vesicular Glutamate Transport Protein 1 | 2012 |
Postherpetic neuralgia: treatment strategies for pain control.
Topics: Amines; Analgesics; Antiviral Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster Vaccine; Humans; Middle Aged; Neuralgia, Postherpetic; Physician Assistants | 2012 |
Gabapentin to pregabalin therapy transition: a pharmacokinetic simulation.
Topics: Amines; Anticonvulsants; Computer Simulation; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Substitution; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Biological; Pregabalin | 2013 |
A man in his seventies with prolonged myasthenic crisis.
Topics: Aged; Amines; Anti-Bacterial Agents; Antibodies, Monoclonal, Murine-Derived; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Male; Methylprednisolone; Myasthenia Gravis; Pneumonia; Respiration, Artificial; Respiratory Insufficiency; Rituximab; Treatment Outcome | 2012 |
The effect of gabapentin on oxidative stress in a model of toxic demyelination in rat brain.
Topics: Amines; Animals; Antioxidants; Cerebral Cortex; Cyclohexanecarboxylic Acids; Demyelinating Diseases; Disease Models, Animal; Dose-Response Relationship, Drug; Ethidium; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2012 |
Long-term outcome of Cavalier King Charles spaniel dogs with clinical signs associated with Chiari-like malformation and syringomyelia.
Topics: Amines; Analgesics; Animals; Arnold-Chiari Malformation; Breeding; Carbazoles; Cohort Studies; Cyclohexanecarboxylic Acids; Dog Diseases; Dogs; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Neuralgia; Pregabalin; Prospective Studies; Quality of Life; Severity of Illness Index; Syringomyelia | 2012 |
Gabapentin shows promise in treating refractory insomnia in children.
Topics: Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Male; Polysomnography; Retrospective Studies; Sleep Initiation and Maintenance Disorders | 2013 |
Relative potency of pregabalin, gabapentin, and morphine in a mouse model of visceral pain.
Topics: Acetic Acid; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Morphine; Pain Measurement; Pregabalin; Visceral Pain | 2013 |
Intended and unintended consequences of the gabapentin off-label marketing lawsuit among patients with bipolar disorder.
Topics: Amines; Anticonvulsants; Bipolar Disorder; Compensation and Redress; Cyclohexanecarboxylic Acids; Drug Approval; Drug Costs; Drug Industry; Drug Information Services; Drug Substitution; Drug Utilization; Gabapentin; gamma-Aminobutyric Acid; Humans; Insurance, Pharmaceutical Services; Marketing; Mass Media; Medicaid; Medicare; Off-Label Use; Practice Patterns, Physicians'; Treatment Outcome; United States | 2012 |
Real-world treatment of post-herpetic neuralgia with gabapentin or pregabalin.
Topics: Adolescent; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Delivery of Health Care; Drug Costs; Drug Substitution; Drug Therapy, Combination; Drug Utilization; Drug Utilization Review; Female; Gabapentin; gamma-Aminobutyric Acid; Guideline Adherence; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Practice Guidelines as Topic; Practice Patterns, Physicians'; Pregabalin; Retrospective Studies; Time Factors; Treatment Outcome; United States; Young Adult | 2013 |
Investigating gabapentin polymorphism using solid-state NMR spectroscopy.
Topics: Amines; Cellulose; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Magnetic Resonance Spectroscopy; Polymorphism, Genetic; Powder Diffraction; Spectrophotometry, Ultraviolet | 2013 |
Gabapentin reduces allodynia and hyperalgesia in painful diabetic neuropathy rats by decreasing expression level of Nav1.7 and p-ERK1/2 in DRG neurons.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NAV1.7 Voltage-Gated Sodium Channel; Nociceptors; Rats; Rats, Sprague-Dawley | 2013 |
Rapid quantification of gabapentin, pregabalin, and vigabatrin in human serum by ultraperformance liquid chromatography with mass-spectrometric detection.
Topics: Amines; Anticonvulsants; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Tandem Mass Spectrometry; Vigabatrin | 2013 |
Rhabdomyolysis in a multiple myeloma patient secondary to concurrent treatment with lenalidomide and pravastatin and to lenalidomide alone.
Topics: Amines; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Boronic Acids; Bortezomib; Combined Modality Therapy; Creatine Kinase, MM Form; Cyclohexanecarboxylic Acids; Dexamethasone; Drug Synergism; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Immunologic Factors; Kidney Diseases; Lenalidomide; Melphalan; Middle Aged; Multiple Myeloma; Peripheral Blood Stem Cell Transplantation; Polyneuropathies; Pravastatin; Pyrazines; Rhabdomyolysis; Thalidomide | 2012 |
[Clinical application of newer anti-epileptic drugs].
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Piracetam; Pregnancy; Pregnancy Complications; Topiramate; Triazines; Zonisamide | 2012 |
Optimised protocol design for the screening of analgesic compounds in neuropathic pain.
Topics: Amines; Analgesics; Animals; Cohort Studies; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; Logistic Models; Models, Biological; Neuralgia; Pregabalin; Random Allocation; Rats; Rats, Sprague-Dawley | 2012 |
Application of ED-optimality to screening experiments for analgesic compounds in an experimental model of neuropathic pain.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Evaluation, Preclinical; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Logistic Models; Models, Biological; Neuralgia; Random Allocation; Rats; Rats, Sprague-Dawley | 2012 |
Persistent hyperalgesia in the cisplatin-treated mouse as defined by threshold measures, the conditioned place preference paradigm, and changes in dorsal root ganglia activated transcription factor 3: the effects of gabapentin, ketorolac, and etanercept.
Topics: Amines; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Behavior, Animal; Cisplatin; Conditioning, Operant; Cyclohexanecarboxylic Acids; Etanercept; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Immunoglobulin G; Immunohistochemistry; Ketorolac Tromethamine; Male; Mice; Mice, Inbred C57BL; Morphine; Pain Threshold; Receptors, Tumor Necrosis Factor; Transcription Factor 3 | 2013 |
Calcitonin for phantom limb pain in a pregnant woman.
Topics: Adult; Amines; Amputation, Surgical; Analgesics, Opioid; Calcitonin; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Phantom Limb; Pregnancy | 2012 |
Long-term use of gabapentin for musculoskeletal disease and trauma in three cats.
Topics: Amines; Analgesics; Animals; Cat Diseases; Cats; Chronic Pain; Craniocerebral Trauma; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Musculoskeletal Diseases | 2013 |
Antioxidants and gabapentin prevent heat hypersensitivity in a neuropathic pain model.
Topics: Amines; Animals; Antioxidants; Calcium Channels; Catalase; Cyclohexanecarboxylic Acids; Drug Combinations; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Ligation; Male; Neuralgia; Pain; Peripheral Nervous System Diseases; Physical Stimulation; Prospective Studies; Rats; Rats, Wistar; Sciatic Nerve; Superoxide Dismutase | 2013 |
Gabapentin and (S)-pregabalin decrease intracellular D-serine concentrations in PC-12 cells.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Intracellular Space; PC12 Cells; Pregabalin; Racemases and Epimerases; Rats; Serine; Stereoisomerism | 2013 |
Mandatory palliative care education for surgical residents: initial focus on teaching pain management.
Topics: Adult; Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Curriculum; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Internship and Residency; Japan; Male; Narcotics; Pain; Pain Management; Palliative Care; Retrospective Studies; Specialties, Surgical; Surveys and Questionnaires; Teaching | 2013 |
Antiepileptic drugs prevent changes in adenosine deamination during acute seizure episodes in adult zebrafish.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Gene Expression; Male; Pentylenetetrazole; Phenytoin; Seizures; Valproic Acid; Zebrafish | 2013 |
Gabapentin in somatoform and panic disorder.
Topics: Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Panic Disorder; Somatoform Disorders; Treatment Outcome | 2013 |
Antiepileptic drugs (AEDs) during pregnancy and risk of congenital jaw and oral malformation.
Topics: Abnormalities, Drug-Induced; Adverse Drug Reaction Reporting Systems; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Data Mining; Datasets as Topic; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Jaw Abnormalities; Lamotrigine; Mouth Abnormalities; Pregnancy; Risk Factors; Topiramate; Triazines; Valproic Acid | 2013 |
Adverse drug reactions to gabapentin and pregabalin: a review of the French pharmacovigilance database.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Databases, Factual; France; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pregabalin | 2013 |
Hot flashes in palliative care. Part 2 #262.
Topics: Amines; Analgesics; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clonidine; Cyclohexanecarboxylic Acids; Drug Interactions; Female; Gabapentin; gamma-Aminobutyric Acid; Hormone Replacement Therapy; Hot Flashes; Humans; Male; Nerve Block; Palliative Care; Prostatic Neoplasms; Selective Serotonin Reuptake Inhibitors; Stellate Ganglion; Tamoxifen | 2013 |
Adjusting for perception and unmasking effects in longitudinal clinical trials.
Topics: Amines; Analgesics; Confounding Factors, Epidemiologic; Cyclohexanecarboxylic Acids; Data Interpretation, Statistical; Diabetic Neuropathies; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Likelihood Functions; Longitudinal Studies; Randomized Controlled Trials as Topic; Regression Analysis; Time Factors | 2012 |
CD30+ lymphomatoid drug reactions.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Amines; Amlodipine; Anti-Bacterial Agents; Anticonvulsants; Biomarkers; Biopsy; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Drug Eruptions; Erythema; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunohistochemistry; Ki-1 Antigen; Levofloxacin; Lymphocytes; Lymphoproliferative Disorders; Male; Metoprolol; Middle Aged; Ofloxacin; Predictive Value of Tests; Pseudolymphoma; Selective Serotonin Reuptake Inhibitors; Sertraline; Skin | 2013 |
Development and validation of sensitive spectrophotometric method for determination of two antiepileptics in pharmaceutical formulations.
Topics: Amines; Anthraquinones; Anticonvulsants; Coloring Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Limit of Detection; Pharmaceutical Preparations; Pregabalin; Spectrophotometry | 2013 |
Chronobiological characteristics of neuropathic pain: clinical predictors of diurnal pain rhythmicity.
Topics: Amines; Analgesics; Analysis of Variance; Circadian Rhythm; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Disease Progression; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Morphine; Neuralgia, Postherpetic; Nortriptyline; Pain Measurement; Periodicity; Predictive Value of Tests; Randomized Controlled Trials as Topic; Sex Factors | 2013 |
Differences in reporting of analyses in internal company documents versus published trial reports: comparisons in industry-sponsored trials in off-label uses of gabapentin.
Topics: Amines; Cyclohexanecarboxylic Acids; Documentation; Drug Industry; Gabapentin; gamma-Aminobutyric Acid; Humans; Off-Label Use; Publishing; Randomized Controlled Trials as Topic; Research Report; Treatment Outcome; Truth Disclosure | 2013 |
Intrathecal gabapentin increases interleukin-10 expression and inhibits pro-inflammatory cytokine in a rat model of neuropathic pain.
Topics: Amines; Analgesics; Animals; Antibodies; Behavior, Animal; Cyclohexanecarboxylic Acids; Cytokines; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Interleukin-10; Male; Neuralgia; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Spinal Cord; Up-Regulation | 2013 |
Managing disruptive and compulsive behaviors in adult with autistic disorder with gabapentin.
Topics: Adult; Amines; Attention Deficit and Disruptive Behavior Disorders; Autistic Disorder; Compulsive Behavior; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Treatment Outcome | 2013 |
Delirium after gabapentin withdrawal. Case report.
Topics: Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Delirium; Electroencephalography; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Neurologic Examination | 2013 |
A study to compare circulating flunixin, meloxicam and gabapentin concentrations with prostaglandin E₂ levels in calves undergoing dehorning.
Topics: Amines; Analgesics; Animals; Area Under Curve; Cattle; Clonixin; Cyclohexanecarboxylic Acids; Dinoprostone; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Horns; Male; Meloxicam; Pain; Random Allocation; Statistics, Nonparametric; Thiazines; Thiazoles | 2013 |
An observational descriptive study of the epidemiology and treatment of neuropathic pain in a UK general population.
Topics: Acetaminophen; Adolescent; Adult; Aged; Amines; Amitriptyline; Analgesics, Non-Narcotic; Analgesics, Opioid; Anticonvulsants; Capsaicin; Child; Child, Preschool; Codeine; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Drug Combinations; Drug Prescriptions; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocodone; Incidence; Infant; Male; Middle Aged; Neuralgia, Postherpetic; Phantom Limb; Practice Patterns, Physicians'; Primary Health Care; Sensory System Agents; United Kingdom; Young Adult | 2013 |
Oral gabapentin suppresses pentylenetetrazole-induced seizure-like behavior and cephalic field potential in adult zebrafish.
Topics: Action Potentials; Administration, Oral; Amines; Analysis of Variance; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Locomotion; Male; Pentylenetetrazole; Seizures; Time Factors; Zebrafish | 2013 |
Combined treatment with gabapentin and drugs affecting the renin-angiotensin system against electroconvulsions in mice.
Topics: Amines; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Anticonvulsants; Avoidance Learning; Benzimidazoles; Benzoates; Brain; Captopril; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electroshock; Enalapril; Gabapentin; gamma-Aminobutyric Acid; Losartan; Male; Mice; Motor Skills; Seizures; Telmisartan | 2013 |
Structure-based ligand discovery for the Large-neutral Amino Acid Transporter 1, LAT-1.
Topics: Amines; Analysis of Variance; Blood-Brain Barrier; Cell Line, Tumor; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Drug Delivery Systems; Flow Cytometry; Gabapentin; gamma-Aminobutyric Acid; Glioblastoma; HEK293 Cells; Humans; Isoxazoles; Large Neutral Amino Acid-Transporter 1; Leucine; Ligands; Models, Molecular; Tritium | 2013 |
Pharmacodynamic effects of a D-amino acid oxidase inhibitor indicate a spinal site of action in rat models of neuropathic pain.
Topics: Amines; Analgesics; Anesthesia; Animals; Behavior, Animal; Constriction, Pathologic; Cyclohexanecarboxylic Acids; D-Amino-Acid Oxidase; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Freund's Adjuvant; Furans; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Ligation; Male; Neuralgia; Physical Stimulation; Pyrroles; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord; Spinal Nerves | 2013 |
Neurological picture. Trigeminal neuralgia after pontine infarction affecting the ipsilateral trigeminal nerve.
Topics: Amines; Analgesics, Non-Narcotic; Carbamazepine; Cerebral Infarction; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Pons; Trigeminal Nerve; Trigeminal Neuralgia | 2013 |
Molecular structure, electronic properties, NLO, NBO analysis and spectroscopic characterization of Gabapentin with experimental (FT-IR and FT-Raman) techniques and quantum chemical calculations.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Models, Molecular; Quantum Theory; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 2013 |
Validation of a novel approach for dose individualization in pharmacotherapy using gabapentin in a proof of principles study.
Topics: Amines; Analgesics; Bayes Theorem; Cyclohexanecarboxylic Acids; Decision Support Techniques; Dose-Response Relationship, Drug; Drug Monitoring; Gabapentin; gamma-Aminobutyric Acid; Humans; Point-of-Care Systems; Precision Medicine; Retrospective Studies; Sensitivity and Specificity; Time Factors | 2013 |
Scalp dysesthesia related to cervical spine disease.
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cervical Vertebrae; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Paresthesia; Retrospective Studies; Scalp; Spinal Diseases; Treatment Outcome | 2013 |
Transport of gabapentin by LAT1 (SLC7A5).
Topics: Amines; Biological Transport; Blood-Brain Barrier; Blotting, Western; Brain; Cell Line; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Large Neutral Amino Acid-Transporter 1; Reverse Transcriptase Polymerase Chain Reaction | 2013 |
Restless legs syndrome as the presenting symptom of multiple myeloma.
Topics: Aged; Amines; Anemia, Iron-Deficiency; Antiparkinson Agents; Benzothiazoles; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Multiple Myeloma; Polysomnography; Pramipexole; Restless Legs Syndrome | 2013 |
Antihyperalgesic activity of a novel synthesized analogue of lidocaine in diabetic rats.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Diabetes Complications; Diabetes Mellitus, Experimental; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Lidocaine; Molecular Structure; Nociceptive Pain; Pain; Pain Measurement; Rats; Reference Values | 2013 |
Temporohyoid osteoarthropathy in two young horses.
Topics: Amines; Animals; Anticonvulsants; Bone Diseases; Cyclohexanecarboxylic Acids; Facial Nerve; Female; Gabapentin; gamma-Aminobutyric Acid; Horse Diseases; Horses; Paralysis; Temporal Bone; Treatment Outcome | 2013 |
Chronic unilateral eruption of painful, erythematous papules and nodules. Piloleiomyoma.
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Leiomyoma; Pain; Skin Neoplasms | 2013 |
Use of low-dose gabapentin for aggressive behavior in vascular and Mixed Vascular/Alzheimer Dementia.
Topics: Aged; Aged, 80 and over; Aggression; Alzheimer Disease; Amines; Cyclohexanecarboxylic Acids; Dementia, Vascular; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; International Classification of Diseases; Male; Retrospective Studies | 2013 |
[Comparison of neuroprotective effects of anticonvulsant drugs in brain injury therapy].
Topics: Amines; Animals; Animals, Outbred Strains; Anticonvulsants; Brain; Brain Injuries; Brain Ischemia; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Stimulation; Fructose; Gabapentin; gamma-Aminobutyric Acid; Lamotrigine; Magnesium Sulfate; Mice; Rats; Seizures; Topiramate; Triazines; Valproic Acid | 2012 |
Topical medications for the effective management of neuropathic orofacial pain.
Topics: Administration, Topical; Amines; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Cranial Nerve Diseases; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Facial Pain; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperesthesia; Iatrogenic Disease; Ketoprofen; Lidocaine; Maxillary Nerve; Middle Aged; Neuralgia; Radicular Cyst | 2013 |
Pregabalin versus gabapentin in the management of peripheral neuropathic pain associated with post-herpetic neuralgia and diabetic neuropathy: a cost effectiveness analysis for the Greek healthcare setting.
Topics: Amines; Analgesics; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Greece; Health Care Costs; Humans; Male; Middle Aged; Neuralgia; Neuralgia, Postherpetic; Pain Measurement; Pregabalin | 2013 |
Treatment of neuropathic pain in acute intermittent porphyria with gabapentin.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pain Threshold; Porphyria, Acute Intermittent | 2013 |
Pfizer versus Kaiser: insurers want their day in court.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Industry; Gabapentin; gamma-Aminobutyric Acid; Humans; Insurance, Health, Reimbursement; Marketing; Off-Label Use; Practice Patterns, Physicians'; United States | 2013 |
Development and optimization of gastroretentive mucoadhesive microspheres of gabapentin by Box-Behnken design.
Topics: Adhesiveness; Amines; Animals; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Drug Liberation; Gabapentin; gamma-Aminobutyric Acid; Gastric Absorption; Gastric Mucosa; Mice; Microspheres; Particle Size | 2014 |
Gabapentin overdose in a military beneficiary.
Topics: Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Drug Overdose; Electrocardiography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Military Personnel | 2013 |
Gabapentin for Postoperative Vomiting in Children Requiring Posterior Fossa Tumor Resection.
Topics: Amines; Cerebellar Neoplasms; Child; Child, Preschool; Craniotomy; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medulloblastoma; Postoperative Nausea and Vomiting | 2015 |
Sickle cell disease with recurrent priapism.
Topics: Adolescent; Amines; Anemia, Sickle Cell; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Priapism; Recurrence | 2012 |
Epilepsy and brain injury: a case report of a dramatic neuropsychiatric vicious circle.
Topics: Accidents, Traffic; Aggression; Amines; Anterior Temporal Lobectomy; Anticonvulsants; Brain Injuries; Carbamazepine; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Disease Progression; Early Diagnosis; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Italy; Male; Middle Aged; Personality Disorders; Quetiapine Fumarate; Time Factors; Topiramate; Treatment Outcome; Valproic Acid | 2013 |
A simple high-throughput method for determination of antiepileptic analogues of γ-aminobutyric acid in pharmaceutical dosage forms using microplate fluorescence reader.
Topics: Amines; Anticonvulsants; Capsules; Cyclohexanecarboxylic Acids; Fluorescamine; Gabapentin; gamma-Aminobutyric Acid; High-Throughput Screening Assays; Pharmaceutical Preparations; Pregabalin; Spectrometry, Fluorescence; Tablets; Temperature; Vigabatrin | 2013 |
Gabapentin-induced pharmacodynamic effects in the spinal nerve ligation model of neuropathic pain.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Male; Neuralgia; Rats; Rats, Sprague-Dawley; Spinal Nerves | 2014 |
Clinical characteristics and medication uses among fibromyalgia patients newly prescribed amitriptyline, duloxetine, gabapentin, or pregabalin.
Topics: Amines; Amitriptyline; Analgesics; Anti-Anxiety Agents; Antidepressive Agents; Cyclohexanecarboxylic Acids; Disease Progression; Duloxetine Hydrochloride; Female; Fibromyalgia; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Measurement; Pregabalin; Prescription Drugs; Retrospective Studies; Thiophenes; Treatment Outcome | 2013 |
Self-inflicted trans-oral intracranial stab wound.
Topics: Amines; Analgesics; Antidepressive Agents; Brain Injuries; Cerebellum; Citalopram; Cyclohexanecarboxylic Acids; Depression; Gabapentin; gamma-Aminobutyric Acid; Head Injuries, Penetrating; Humans; Magnetic Resonance Imaging; Male; Medulla Oblongata; Middle Aged; Self-Injurious Behavior; Treatment Outcome; Wounds, Stab | 2013 |
Effects of gabapentin on thermal sensitivity following spinal nerve ligation or spinal cord compression.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Conditioning, Operant; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Escape Reaction; Gabapentin; gamma-Aminobutyric Acid; Male; Neuralgia; Rats; Rats, Long-Evans; Spinal Cord Compression; Spinal Nerves; Temperature | 2013 |
[Occipital neuralgia: clinical and therapeutic characteristics of a series of 14 patients].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Headache Disorders, Primary; Humans; Male; Middle Aged; Nerve Block; Neuralgia; Pain Management; Pain Measurement; Recurrence; Trigeminal Autonomic Cephalalgias; Young Adult | 2013 |
Neuropathic pain following sagittal split ramus osteotomy of the mandible: prevalence, risk factors, and clinical course.
Topics: Adult; Age Factors; Amines; Anticonvulsants; Antidepressive Agents, Tricyclic; Cohort Studies; Cyclohexanecarboxylic Acids; Depression; Facial Pain; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mandibular Fractures; Middle Aged; Neuralgia; Osteotomy, Sagittal Split Ramus; Pain, Postoperative; Prevalence; Retrospective Studies; Risk Factors; Sensation Disorders; Sex Factors; Young Adult | 2013 |
Macroglossia associated with brainstem injury.
Topics: Adolescent; Adrenergic beta-Antagonists; Aged; Amines; Anti-Inflammatory Agents; Brain Injuries; Brain Stem; Calcium Channel Blockers; Cranial Fossa, Posterior; Cyclohexanecarboxylic Acids; Dexamethasone; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Macroglossia; Male; Middle Aged; Primary Dysautonomias; Tracheostomy; Treatment Outcome | 2014 |
Globus pharyngeus: effectiveness of treatment with proton pump inhibitors and gabapentin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Deglutition Disorders; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pharyngitis; Proton Pump Inhibitors; Retrospective Studies; Sensation Disorders; Treatment Outcome; Young Adult | 2013 |
Evaluation of two modified quick, easy, cheap, effective, rugged and safe (QuEChERS) sample preparation methods for the analysis of baclofen and gabapentin in feeds by liquid chromatography tandem mass spectrometry.
Topics: Acetonitriles; Amines; Animal Feed; Baclofen; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Formates; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Mass Spectrometry; Methanol; Reproducibility of Results; Time Factors; Water | 2014 |
[Lacosamide as an alternative in the treatment of post-surgery neuropathic pain in an allergic patient].
Topics: Acetamides; Adult; Amines; Analgesics; Anticonvulsants; Brachial Plexus Neuropathies; Contraindications; Cyclohexanecarboxylic Acids; Drug Hypersensitivity; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lacosamide; Magnetic Resonance Imaging; Neuralgia; Neurofibroma; Pain, Postoperative; Peripheral Nervous System Neoplasms; Pregabalin | 2013 |
Episodic itch in a case of spinal glioma.
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Evoked Potentials, Somatosensory; Female; Gabapentin; gamma-Aminobutyric Acid; Glioma; Humans; Magnetic Resonance Imaging; Pruritus; Reaction Time; Spinal Cord Neoplasms | 2013 |
Acute dystonic reaction caused by gabapentin.
Topics: Acute Disease; Adult; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Dystonia; Gabapentin; gamma-Aminobutyric Acid; Humans; Illicit Drugs; Male; Substance-Related Disorders | 2014 |
Cardiac surgery and C1-inhibitor deficiency.
Topics: Aged, 80 and over; Amines; Analgesics; Anesthesia; Angioedemas, Hereditary; Antifibrinolytic Agents; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Complement C1 Inhibitor Protein; Complement Inactivating Agents; Cyclohexanecarboxylic Acids; Danazol; Estrogen Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Histamine H1 Antagonists; Humans; Hydroxyzine; Preoperative Care; Tranexamic Acid | 2014 |
siRNA screen for genes that affect Junín virus entry uncovers voltage-gated calcium channels as a therapeutic target.
Topics: Amines; Animals; Calcium Channel Blockers; Calcium Channels; Cell Fusion; Cell Line, Tumor; Cell Membrane; Chlorocebus aethiops; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gene Knockdown Techniques; High-Throughput Screening Assays; Host-Pathogen Interactions; Humans; Junin virus; Mice; Molecular Targeted Therapy; Protein Binding; Protein Subunits; Receptors, Transferrin; RNA Interference; RNA, Small Interfering; Vero Cells; Virus Internalization | 2013 |
31-year-old woman with alopecia.
Topics: Adult; Alopecia; Amines; Analgesics; Anemia, Iron-Deficiency; Ascorbic Acid; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Drug Combinations; Female; Ferrous Compounds; Gabapentin; gamma-Aminobutyric Acid; Humans; Menorrhagia; Thyroid Diseases; Thyroid Function Tests | 2013 |
Adding pregabalin or gabapentin for the management of community-treated patients with painful diabetic peripheral neuropathy: a comparative cost analysis.
Topics: Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Diabetic Nephropathies; Drug Costs; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Longitudinal Studies; Male; Medical Audit; Middle Aged; Pregabalin; Retrospective Studies | 2013 |
Gabapentin alleviates facet-mediated pain in the rat through reduced neuronal hyperexcitability and astrocytic activation in the spinal cord.
Topics: Amines; Analgesics; Animals; Arthralgia; Astrocytes; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Neurons; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord; Zygapophyseal Joint | 2013 |
C5 and C7 intramolecular hydrogen bonds stabilize the structure of N-pyrazinoyl-gabapentin (Pyr-Gpn-OH).
Topics: Amines; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Cyclohexanes; Gabapentin; gamma-Aminobutyric Acid; Hydrogen Bonding; Molecular Conformation; Molecular Structure; Pyrazines | 2013 |
Semi-mechanistic modelling of the analgesic effect of gabapentin in the formalin-induced rat model of experimental pain.
Topics: Amines; Analgesics; Animals; Computer Simulation; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Models, Biological; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley | 2014 |
Oral gabapentin treatment accentuates nerve and peripheral inflammatory responses following experimental nerve constriction in Wistar rats.
Topics: Administration, Oral; Amines; Analgesics; Animals; Cell Movement; Constriction, Pathologic; Cyclohexanecarboxylic Acids; Cytokines; Edema; Gabapentin; gamma-Aminobutyric Acid; Inflammation; Male; Motor Activity; Neuralgia; Peritoneal Cavity; Rats; Rats, Wistar; Sciatic Nerve | 2013 |
Assessment of paclitaxel induced sensory polyneuropathy with "Catwalk" automated gait analysis in mice.
Topics: Amines; Animals; Antineoplastic Agents; Automation; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; Gait; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Paclitaxel; Peripheral Nervous System; Polyneuropathies | 2013 |
Effects of derivatization reagents consisting of n-alkyl chloroformate/n-alcohol combinations in LC-ESI-MS/MS analysis of zwitterionic antiepileptic drugs.
Topics: 1-Propanol; Amines; Anticonvulsants; Butanols; Cyclohexanecarboxylic Acids; Esters; Ethanol; Formates; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Methanol; Pregabalin; Solutions; Spectrometry, Mass, Electrospray Ionization; Vigabatrin | 2013 |
Isobolographic analysis in mice of the interaction of gabapentin and nortriptyline in relieving orofacial pain.
Topics: Amines; Animals; Anticonvulsants; Antidepressive Agents; Cyclohexanecarboxylic Acids; Drug Synergism; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Linear Models; Male; Mice; Mice, Inbred Strains; Nortriptyline | 2013 |
The role of keratinocyte-derived chemokine (KC) on hyperalgesia caused by peripheral nerve injury in mice.
Topics: Amines; Analgesics; Animals; Antibodies; Chemokines; Cyclohexanecarboxylic Acids; Cyclooxygenase Inhibitors; Cytokines; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Immunologic Factors; Indomethacin; Male; Mice; Neuralgia; Peripheral Nerve Injuries; Phenylurea Compounds; Receptors, Interleukin-8B; Sciatic Nerve; Spinal Cord; Touch; Vinblastine | 2014 |
Gabapentin: a new addition to the armamentarium for alcohol dependence?
Topics: Alcoholism; Amines; Cyclohexanecarboxylic Acids; Female; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Male | 2014 |
Gabapentinoid abuse in order to potentiate the effect of methadone: a survey among substance misusers.
Topics: Amines; Behavior, Addictive; Cyclohexanecarboxylic Acids; Data Collection; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Humans; Methadone; Opioid-Related Disorders; Pregabalin; Scotland; Substance-Related Disorders | 2014 |
Compounded ointment results in severe toxicity in a pediatric patient.
Topics: Administration, Cutaneous; Amines; Analgesics; Body Surface Area; Bradycardia; Clonidine; Combined Modality Therapy; Consciousness Disorders; Cyclohexanecarboxylic Acids; Diaper Rash; Drug Combinations; Drug Compounding; Drug Overdose; Emergencies; Gabapentin; gamma-Aminobutyric Acid; Humans; Imipramine; Infant; Intensive Care Units, Pediatric; Intubation, Intratracheal; Ketamine; Lidocaine; Male; Mefenamic Acid; Ointments; Reflex, Abnormal; Respiration Disorders; Skin Absorption | 2013 |
Treatment of pediatric restless legs syndrome.
Topics: Adolescent; Amines; Analgesics; Anticonvulsants; Antioxidants; Benzothiazoles; Child; Child, Preschool; Clonidine; Cyclohexanecarboxylic Acids; Dopamine Agonists; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Iron; Male; Melatonin; Mental Disorders; Pediatrics; Polysomnography; Pramipexole; Restless Legs Syndrome; Retrospective Studies; Sleep Wake Disorders; Treatment Outcome | 2014 |
Bad medicine: gabapentin and pregabalin.
Topics: Amines; Analgesics; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Drug Overdose; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Iatrogenic Disease; Male; Practice Patterns, Physicians'; Pregabalin; Prescription Drug Misuse; Prescription Drugs; United States | 2013 |
Low back pain radiating to the leg: an atypical cause.
Topics: Amines; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Cyclophosphamide; Delayed Diagnosis; Diagnosis, Differential; Doxorubicin; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intervertebral Disc Displacement; Low Back Pain; Lumbar Vertebrae; Lymphoma, B-Cell; Manipulation, Chiropractic; Middle Aged; Osteolysis; Prednisone; Radiography; Remission Induction; Sciatica; Vincristine | 2013 |
Gabapentin attenuates morphine tolerance through interleukin-10.
Topics: Amines; Analgesics; Analysis of Variance; Animals; Antibodies; Cyclohexanecarboxylic Acids; Cytokines; Dose-Response Relationship, Drug; Drug Tolerance; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Spinal; Interleukin-10; Male; Morphine; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors | 2014 |
Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus.
Topics: Amines; Animals; Astrocytes; Cyclohexanecarboxylic Acids; Electroencephalography; Gabapentin; gamma-Aminobutyric Acid; Gliosis; Glutamic Acid; Hippocampus; Humans; Male; Nestin; Neuroglia; Neurons; Pilocarpine; Rats; Seizures; Status Epilepticus | 2013 |
[Therapeuetic aspects of cluster headache in the practical clinical site].
Topics: Adult; Amines; Amitriptyline; Cluster Headache; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Subcutaneous; Male; Middle Aged; Self Care; Sumatriptan; Valproic Acid; Young Adult | 2013 |
Effectiveness of duloxetine compared with pregabalin and gabapentin in diabetic peripheral neuropathic pain: results from a German observational study.
Topics: Aged; Amines; Analgesics; Chi-Square Distribution; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Health Surveys; Humans; Male; Middle Aged; Pain Measurement; Pregabalin; Prospective Studies; Thiophenes; Treatment Outcome | 2014 |
Glia and epilepsy: experimental investigation of antiepileptic drugs in an astroglia/microglia co-culture model of inflammation.
Topics: Amines; Animals; Anticonvulsants; Astrocytes; Blotting, Western; Carbamazepine; Cells, Cultured; Coculture Techniques; Connexin 43; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Gap Junctions; Inflammation; Microglia; Neuroglia; Phenytoin; Rats; Rats, Wistar; Transforming Growth Factor beta1; Valproic Acid | 2014 |
Differential upregulation in DRG neurons of an α2δ-1 splice variant with a lower affinity for gabapentin after peripheral sensory nerve injury.
Topics: Amines; Animals; Calcium Channels; Calcium Channels, L-Type; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Male; Peripheral Nerve Injuries; Protein Binding; Protein Isoforms; Rabbits; Rats; Rats, Sprague-Dawley; Up-Regulation | 2014 |
Drugs for neuropathic pain.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Therapy, Combination; Duloxetine Hydrochloride; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pregabalin; Thiophenes; Treatment Outcome | 2013 |
Differential pharmacological alleviation of oxaliplatin-induced hyperalgesia/allodynia at cephalic versus extra-cephalic level in rodents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amines; Analgesics; Animals; Cold Temperature; Cyclohexanecarboxylic Acids; Dipeptides; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Morphine; Organoplatinum Compounds; Oxaliplatin; Piperazines; Piperidines; Quinazolines; Rats; Rats, Sprague-Dawley; Spinal Cord; Touch; TRPA1 Cation Channel; TRPC Cation Channels; Tryptamines | 2014 |
Spinal morphine but not ziconotide or gabapentin analgesia is affected by alternative splicing of voltage-gated calcium channel CaV2.2 pre-mRNA.
Topics: Alternative Splicing; Amines; Analgesia; Animals; Calcium Channels, N-Type; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Morphine; Neuralgia; omega-Conotoxins; RNA Precursors | 2013 |
Memory-related gene expression profile of the male rat hippocampus induced by teeth extraction and occlusal support recovery.
Topics: Amines; Animals; Calgranulin B; Cyclohexanecarboxylic Acids; Dental Occlusion; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Profiling; Hippocampus; Male; Maze Learning; Memory; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Tenascin; Thyrotropin-Releasing Hormone; Tooth Extraction | 2014 |
The anticonvulsant enaminone E139 attenuates paclitaxel-induced neuropathic pain in rodents.
Topics: Amines; Amitriptyline; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Cyclohexanes; Female; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Mice; Mice, Inbred BALB C; Neuralgia; Paclitaxel; Rats; Rats, Sprague-Dawley | 2013 |
Increasing glutamate promotes ischemia-reperfusion-induced ventricular arrhythmias in rats in vivo.
Topics: Amines; Animals; Arrhythmias, Cardiac; Calcium; Cells, Cultured; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Heart Ventricles; Kainic Acid; Male; Mitochondria, Heart; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2014 |
Should anaesthetists routinely use a gabapentinoid perioperatively?
Topics: Amines; Analgesics; Anesthesiology; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain, Postoperative; Perioperative Care; Pregabalin | 2014 |
Chronic effect of gabapentin on liver function in adult male rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Amines; Animals; Aspartate Aminotransferases; Bilirubin; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; L-Lactate Dehydrogenase; Liver; Liver Function Tests; Male; Rats; Rats, Wistar | 2013 |
Gabapentin hybrid peptides and bioconjugates.
Topics: Acylation; Amines; Analgesics; Animals; Behavior, Animal; Crystallography, X-Ray; Cyclization; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Mice; Molecular Conformation; Pain; Peptides | 2014 |
Severe respiratory depression associated with perioperative opioid-sparing gabapentin use.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Respiratory Insufficiency | 2014 |
Painful traumatic trigeminal neuropathy: an open study on the pharmacotherapeutic response to stepped treatment.
Topics: Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Baclofen; Carbamazepine; Clinical Protocols; Cohort Studies; Cyclohexanecarboxylic Acids; Drug Combinations; Duloxetine Hydrochloride; Female; Follow-Up Studies; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medical Records; Middle Aged; Nortriptyline; Pain; Pain Measurement; Pregabalin; Prognosis; Prospective Studies; Thiophenes; Treatment Outcome; Trigeminal Nerve Injuries; Trigeminal Neuralgia | 2014 |
Antinociceptive effects of mirtazapine, pregabalin, and gabapentin after chronic constriction injury of the infraorbital nerve in rats.
Topics: Adrenergic alpha-Antagonists; Amines; Analgesics; Animals; Cranial Nerve Injuries; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Injections, Spinal; Male; Mianserin; Mirtazapine; Neuralgia; Nociceptive Pain; Orbit; Pain Threshold; Pregabalin; Rats; Rats, Sprague-Dawley; Time Factors; Touch | 2014 |
Gabapentin increases extracellular glutamatergic level in the locus coeruleus via astroglial glutamate transporter-dependent mechanisms.
Topics: Amines; Amino Acid Transport System X-AG; Animals; Astrocytes; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Locus Coeruleus; Male; Neuralgia; Norepinephrine; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Spinal Nerves; Time Factors | 2014 |
Gabapentin can improve dystonia in confirmed Wilson disease.
Topics: Adult; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Dystonia; Female; Gabapentin; gamma-Aminobutyric Acid; Hepatolenticular Degeneration; Humans; Treatment Outcome | 2014 |
Gabapentin for Substance Use Disorders: Is it Safe and Appropriate?
Topics: Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Drug Prescriptions; Gabapentin; gamma-Aminobutyric Acid; Humans; Prescription Drug Misuse; Safety; Substance Withdrawal Syndrome; United States; United States Food and Drug Administration | 2014 |
Chronic postsurgical pain: prevention and management.
Topics: Amines; Chronic Pain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Management; Pain, Postoperative; Pregabalin; Risk Factors | 2014 |
Gabapentin enhances the morphine anti-nociceptive effect in neuropathic pain via the interleukin-10-heme oxygenase-1 signalling pathway in rats.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Heme Oxygenase-1; Interleukin-10; Interleukin-1beta; Interleukin-6; Male; Morphine; Neuralgia; Nociception; Protoporphyrins; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Necrosis Factor-alpha | 2014 |
Gabapentin: can it be misused?
Topics: Amines; Controlled Substances; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Male; Norway; Prescription Drug Misuse; Risk Assessment; Scotland; Substance Withdrawal Syndrome; Substance-Related Disorders; United Kingdom | 2014 |
Polymorphism control of an active pharmaceutical ingredient beneath calixarene-based Langmuir monolayers.
Topics: Amines; Calixarenes; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Models, Molecular; Molecular Structure; Pharmaceutical Preparations | 2014 |
Investigation on gabapentin residues in eggs from free-range hens exposed to saline slags from pharmaceutical industry.
Topics: Amines; Analgesics; Animals; Chickens; Cyclohexanecarboxylic Acids; Drug Industry; Eggs; Female; Gabapentin; gamma-Aminobutyric Acid; Herbivory; Industrial Waste; Soil Pollutants | 2014 |
Effect of gabapentin on swallowing during and after chemoradiation for oropharyngeal squamous cell cancer.
Topics: Amines; Analgesics; Carcinoma, Squamous Cell; Chemoradiotherapy; Cyclohexanecarboxylic Acids; Deglutition; Eating; Enteral Nutrition; Female; Gabapentin; gamma-Aminobutyric Acid; Gastrostomy; Humans; Male; Middle Aged; Mucositis; Oropharyngeal Neoplasms; Pain; Retrospective Studies | 2014 |
Patient demographics and health plan paid costs in chronic inflammatory demyelinating polyneuropathy.
Topics: Adolescent; Adult; Aged; Algorithms; Amines; Analgesics; Anti-Inflammatory Agents; Comorbidity; Costs and Cost Analysis; Cyclohexanecarboxylic Acids; Drug Costs; Electromyography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunoglobulins, Intravenous; Insurance, Health; International Classification of Diseases; Male; Middle Aged; Neural Conduction; Neurologic Examination; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Prednisolone; Socioeconomic Factors; United States; Young Adult | 2014 |
Impact of oral meloxicam administered alone or in combination with gabapentin on experimentally induced lameness in beef calves.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cattle Diseases; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Lameness, Animal; Male; Meloxicam; Thiazines; Thiazoles | 2014 |
Pharmacological characterization of standard analgesics on oxaliplatin-induced acute cold hypersensitivity in mice.
Topics: Acute Disease; Amines; Analgesics; Animals; Antineoplastic Agents; Calcium Gluconate; Cryopyrin-Associated Periodic Syndromes; Cyclohexanecarboxylic Acids; Cyclopropanes; Gabapentin; gamma-Aminobutyric Acid; Male; Mexiletine; Mice; Mice, Inbred C57BL; Milnacipran; Morphine; Organoplatinum Compounds; Oxaliplatin; Tramadol | 2014 |
Phantom organ pain syndrome, a ghostly visitor to the ED.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Emergency Service, Hospital; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Nephrectomy; Phantom Limb; Pyelonephritis; Syndrome | 2014 |
Gabapentin inhibits bortezomib-induced mechanical allodynia through supraspinal action in mice.
Topics: Adrenergic Neurons; Amines; Animals; Antineoplastic Agents; Boronic Acids; Bortezomib; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Mice; Mice, Inbred C57BL; Norepinephrine; Pyrazines; Spinal Cord | 2014 |
[Pulsed radiofrequency in the treatment of abdominal cutaneous nerve entrapament syndrome].
Topics: Abdomen; Adult; Amines; Amitriptyline; Anesthetics, Local; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Emergencies; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Nerve Block; Nerve Compression Syndromes; Pain Management; Pulsed Radiofrequency Treatment; Skin; Triamcinolone Acetonide | 2015 |
Hot flashes: is a hot flash just a hot flash?
Topics: Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans | 2014 |
Ligation of mouse L4 and L5 spinal nerves produces robust allodynia without major motor function deficit.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Ligation; Male; Mice; Motor Skills; Nerve Degeneration; Neuralgia; Paraplegia; Spinal Nerves | 2015 |
Anti-allodynic and neuroprotective effects of koumine, a Benth alkaloid, in a rat model of diabetic neuropathy.
Topics: Amines; Animals; Blood Glucose; Body Weight; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Indole Alkaloids; Male; Nerve Degeneration; Neural Conduction; Neuralgia; Neuroprotective Agents; Pain Measurement; Rats; Sciatic Nerve; Sensory Receptor Cells | 2014 |
Modulation of voltage-gated Ca2+ channels in rat retinal ganglion cells by gabapentin.
Topics: Amines; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Membrane Potentials; Patch-Clamp Techniques; Rats, Long-Evans; Retinal Ganglion Cells | 2014 |
Gabapentin, a synthetic analogue of gamma aminobutyric acid, reverses systemic acute inflammation and oxidative stress in mice.
Topics: Acute Disease; Amines; Animals; Anti-Inflammatory Agents; Cyclohexanecarboxylic Acids; Edema; Gabapentin; gamma-Aminobutyric Acid; Inflammation; Male; Mice; Oxidative Stress; Random Allocation | 2014 |
Successful treatment of antipsychotic-induced restless legs syndrome with gabapentin.
Topics: Amines; Antipsychotic Agents; Benzodiazepines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Olanzapine; Restless Legs Syndrome; Schizophrenia, Paranoid; Treatment Outcome | 2014 |
Nummular headache in a patient with ipsilateral occipital neuralgia--a case report.
Topics: Amines; Analgesics; Anesthetics, Local; Bupivacaine; Comorbidity; Cyclohexanecarboxylic Acids; Female; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Magnetic Resonance Imaging; Mianserin; Middle Aged; Neuralgia; Occipital Bone; Serotonin Antagonists; Treatment Outcome | 2014 |
Effect of variability in the 7-day baseline pain diary on the assay sensitivity of neuropathic pain randomized clinical trials: an ACTTION study.
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Neuralgia, Postherpetic; Pain Measurement; Pregabalin; Randomized Controlled Trials as Topic; Self Report; Treatment Outcome; United States | 2014 |
Profiles of pregabalin and gabapentin abuse by postmortem toxicology.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Female; Finland; Forensic Toxicology; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Male; Mass Spectrometry; Middle Aged; Narcotics; Postmortem Changes; Pregabalin; Substance-Related Disorders; Young Adult | 2014 |
Peripheral nerve injury and gabapentin, but not their combination, impair attentional behavior via direct effects on noradrenergic signaling in the brain.
Topics: Adrenergic Neurons; Amines; Analgesics; Animals; Attention; Behavior, Animal; Chronic Pain; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Microdialysis; Norepinephrine; Peripheral Nerve Injuries; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Signal Transduction; Synaptosomes | 2014 |
Treatment of climacteric symptoms in breast cancer patients: a retrospective study from a medication databank.
Topics: Aged; Amines; Antidepressive Agents; Antineoplastic Agents; Aromatase Inhibitors; Belgium; Breast Neoplasms; Climacteric; Clonidine; Cyclohexanecarboxylic Acids; Databases, Factual; Drug Interactions; Estrogen Replacement Therapy; Estrogens; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Menopause, Premature; Middle Aged; Retrospective Studies; Self Medication; Survivors; Tamoxifen; Vaginal Creams, Foams, and Jellies | 2014 |
Activation of mesocorticolimbic reward circuits for assessment of relief of ongoing pain: a potential biomarker of efficacy.
Topics: Amines; Analgesics; Animals; Biomarkers; Cyclohexanecarboxylic Acids; Dopamine; Gabapentin; gamma-Aminobutyric Acid; Male; Microdialysis; Neuralgia; Nucleus Accumbens; Pain; Rats; Rats, Sprague-Dawley; Reward; Treatment Outcome | 2014 |
Potentiation of the effect of buprenorphine/naloxone with gabapentin or quetiapine.
Topics: Adult; Amines; Analgesics; Buprenorphine; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Naloxone; Narcotic Antagonists; Opiate Substitution Treatment; Prescription Drug Misuse; Quetiapine Fumarate | 2014 |
Functional exofacially tagged N-type calcium channels elucidate the interaction with auxiliary α2δ-1 subunits.
Topics: Amines; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Cell Line, Tumor; Cell Membrane; Cyclohexanecarboxylic Acids; Electrophysiology; Epitopes; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Ligands; Mice; Neuroblastoma; Neurons; Protein Structure, Tertiary; Rabbits; Rats; Rats, Sprague-Dawley | 2014 |
Gas chromatography-electron ionization-mass spectrometry quantitation of valproic acid and gabapentin, using dried plasma spots, for therapeutic drug monitoring in in-home medical care.
Topics: Acetamides; Amines; Cyclohexanecarboxylic Acids; Dried Blood Spot Testing; Fluoroacetates; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Trimethylsilyl Compounds; Valproic Acid | 2014 |
Uremic pruritus is improved by gabapentin.
Topics: Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pruritus; Renal Dialysis; Uremia | 2014 |
Deep renal ectopia causing sciatic mononeuropathy.
Topics: Adolescent; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Diseases; Magnetic Resonance Imaging; Sciatic Neuropathy | 2014 |
Simultaneous determination of gabapentin, pregabalin, vigabatrin, and topiramate in plasma by HPLC with fluorescence detection.
Topics: Amines; Anticonvulsants; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Fluorescence; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Limit of Detection; Pregabalin; Solid Phase Extraction; Topiramate; Vigabatrin | 2014 |
Soluble epoxide hydrolase inhibition is antinociceptive in a mouse model of diabetic neuropathy.
Topics: Amines; Analgesics; Animals; Benzoates; Chronic Pain; Conditioning, Psychological; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epoxide Hydrolases; Gabapentin; gamma-Aminobutyric Acid; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neuralgia; Nociceptive Pain; Pain Threshold; Phenylurea Compounds; Space Perception | 2014 |
A method to enhance the magnitude of tactile hypersensitivity following spinal nerve ligation in rats.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Ligation; Lumbar Vertebrae; Male; Pain Measurement; Pain Threshold; Physical Stimulation; Random Allocation; Rats, Sprague-Dawley; Sensitivity and Specificity; Spinal Nerves; Touch | 2014 |
Effects of NB001 and gabapentin on irritable bowel syndrome-induced behavioral anxiety and spontaneous pain.
Topics: Adenosine Triphosphate; Amines; Animals; Anxiety; Behavior, Animal; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Irritable Bowel Syndrome; Male; Mice; Mice, Inbred C57BL; Pain; Proto-Oncogene Proteins c-fos; Up-Regulation; Visceral Pain; Zymosan | 2014 |
Transient hypothyroidism induced by anticonvulsant agents.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypothyroidism; Thyroxine; Trigeminal Neuralgia; Valproic Acid | 2014 |
Validation and additional support for an experimental animal model of fibromyalgia.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Dinoprostone; Disease Models, Animal; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Interleukin-1beta; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Nitric Oxide | 2015 |
Evidence, regulation and 'rational' prescribing: the case of gabapentin for neuropathic pain.
Topics: Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Off-Label Use; Practice Patterns, Physicians' | 2015 |
Gabapentin prevents oxaliplatin-induced mechanical hyperalgesia in mice.
Topics: Actin Depolymerizing Factors; Amines; Animals; Antineoplastic Agents; Cold Temperature; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Intraperitoneal; Male; Mice, Inbred Strains; Organoplatinum Compounds; Oxaliplatin; Phosphorylation; Spinal Cord | 2014 |
Albumin nanoparticles for the delivery of gabapentin: preparation, characterization and pharmacodynamic studies.
Topics: Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Carriers; Drug Compounding; Electroshock; Gabapentin; gamma-Aminobutyric Acid; Male; Nanoparticles; Pentylenetetrazole; Polysorbates; Rats, Wistar; Seizures; Serum Albumin, Bovine | 2014 |
Effects of single and combined gabapentin use in elevated plus maze and forced swimming tests.
Topics: Amines; Amitriptyline; Animals; Anticonvulsants; Anxiety; Cyclohexanecarboxylic Acids; Depression; Diazepam; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Ketamine; Maze Learning; Rats; Rats, Sprague-Dawley; Sertraline; Swimming; Treatment Outcome | 2014 |
Gabapentin Enhances Neurogenesis in E14 Rat Embryonic Neocortex Stem Cells.
Topics: Amines; Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Mood Disorders; Neocortex; Neurogenesis; Neurons; Rats; Rats, Sprague-Dawley; Stem Cells | 2015 |
Real-world experience with once-daily gabapentin for the treatment of postherpetic neuralgia (PHN).
Topics: Administration, Inhalation; Adolescent; Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia, Postherpetic; Pain Measurement; Pragmatic Clinical Trials as Topic; Treatment Outcome; Young Adult | 2015 |
Suppression of network activity in dorsal horn by gabapentin permeation of TRPV1 channels: implications for drug access to cytoplasmic targets.
Topics: Amines; Analgesics; Animals; Calcium; Capsaicin; Cells, Cultured; Cyclohexanecarboxylic Acids; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Male; Neurons; Patch-Clamp Techniques; Permeability; Rats, Sprague-Dawley; Spinal Cord Dorsal Horn; TRPV Cation Channels | 2015 |
Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy.
Topics: Administration, Oral; Amines; Analgesics; Animals; Biological Availability; Chemistry Techniques, Synthetic; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Drug Design; Enzyme Inhibitors; Epoxide Hydrolases; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mice; Molecular Targeted Therapy; Neuralgia; Rats, Sprague-Dawley; Solubility; Structure-Activity Relationship; Time Factors | 2014 |
Augmentation in restless legs syndrome patients in Korea.
Topics: Aged; Aged, 80 and over; Amines; Benzothiazoles; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Disease Progression; Dopamine Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Indoles; Korea; Long-Term Care; Male; Middle Aged; Pramipexole; Pregabalin; Restless Legs Syndrome; Risk Factors | 2015 |
Misuse of the γ-aminobutyric acid analogues baclofen, gabapentin and pregabalin in the UK.
Topics: Adolescent; Adult; Amines; Baclofen; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Humans; Illicit Drugs; Male; Middle Aged; Pregabalin; Prescription Drug Misuse; United Kingdom; Young Adult | 2014 |
Effect of histone deacetylase inhibitor JNJ-26481585 in pain.
Topics: Amines; Animals; Antineoplastic Agents; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Histone Deacetylase Inhibitors; Hydroxamic Acids; Hyperalgesia; Interleukin-1beta; Macrophages; Male; Mice; Mice, Inbred C57BL; Neuralgia; NF-kappa B; Spinal Cord | 2015 |
An unusual conformation of gabapentin (Gpn) in Pyr-Gpn-NH-NH-Pyr stabilized by weak interactions.
Topics: Amines; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrazines; Hydrogen Bonding; Molecular Conformation; Molecular Structure; Pyrazines; Stereoisomerism | 2014 |
Neuro-Behçet disease presenting with oculopalatal tremor.
Topics: Adult; Amines; Anticonvulsants; Behcet Syndrome; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Neurologic Examination; Nystagmus, Pathologic; Olivary Nucleus; Tremor; Vestibular Diseases | 2015 |
Gabapentin-induced myoclonus in an elderly with end-stage renal failure.
Topics: Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Myoclonus | 2014 |
Permeability analysis of neuroactive drugs through a dynamic microfluidic in vitro blood-brain barrier model.
Topics: Amines; Animals; Benzazepines; Biological Transport; Blood-Brain Barrier; Cell Survival; Cells, Cultured; Coculture Techniques; Cyclohexanecarboxylic Acids; Endothelial Cells; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Indoles; L-Lactate Dehydrogenase; Mice; Microfluidic Analytical Techniques; Neuroglia; Permeability; Piperidines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Sertraline; Sunitinib; Tetrahydronaphthalenes; Valine; Varenicline | 2014 |
Analysis of the long-term actions of gabapentin and pregabalin in dorsal root ganglia and substantia gelatinosa.
Topics: Amines; Analgesics; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cyclohexanecarboxylic Acids; Excitatory Postsynaptic Potentials; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Immunohistochemistry; Inhibitory Postsynaptic Potentials; Male; Microscopy, Confocal; Neurons; Patch-Clamp Techniques; Pregabalin; Rats, Sprague-Dawley; Substantia Gelatinosa; Tissue Culture Techniques | 2014 |
Gabapentin attenuates hyperexcitability in the freeze-lesion model of developmental cortical malformation.
Topics: Age Factors; Amines; Animals; Animals, Newborn; Anticonvulsants; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electric Stimulation; Epilepsy; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Freezing; Gabapentin; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamic Acid; In Vitro Techniques; Kainic Acid; Malformations of Cortical Development; Mice; Mice, Inbred C57BL; Neuroimaging; Patch-Clamp Techniques; Somatosensory Cortex; Thrombospondins | 2014 |
Gabapentin as a potential treatment for cough syncope.
Topics: Amines; Antitussive Agents; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Syncope | 2015 |
Use of non-opioid analgesics as adjuvants to opioid analgesia for cancer pain management in an inpatient palliative unit: does this improve pain control and reduce opioid requirements?
Topics: Aged; Amines; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Morphine; Neoplasms; Pain; Pain Management; Pain Measurement; Palliative Care; Prospective Studies; Retrospective Studies; Treatment Outcome | 2015 |
Effects of intravenous human umbilical cord blood mesenchymal stem cell therapy versus gabapentin in pentylenetetrazole-induced chronic epilepsy in rats.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intraperitoneal; Injections, Intravenous; Mesenchymal Stem Cell Transplantation; Oxidative Stress; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Umbilical Cord | 2014 |
In vivo and in vitro evaluations of intestinal gabapentin absorption: effect of dose and inhibitors on carrier-mediated transport.
Topics: Administration, Oral; Amines; Amino Acids, Cyclic; Animals; Caco-2 Cells; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Intestinal Absorption; Intestinal Mucosa; Male; Membrane Transport Modulators; Membrane Transport Proteins; Models, Biological; Rats, Sprague-Dawley | 2015 |
Development and pharmacological characterization of a model of sleep disruption-induced hypersensitivity in the rat.
Topics: Amines; Animals; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Hypersensitivity; Male; Pain; Pain Threshold; Rats, Wistar; Sleep | 2015 |
Gabapentin-induced encephalopathy.
Topics: Aged, 80 and over; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Electroencephalography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Neurotoxicity Syndromes | 2015 |
Second generation anti-epileptic drugs adversely affect reproductive functions in young non-epileptic female rats.
Topics: Amines; Animals; Anticonvulsants; Astrocytes; Blotting, Western; Body Weight; Cyclohexanecarboxylic Acids; Enzyme-Linked Immunosorbent Assay; Estradiol; Estrous Cycle; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Insulin; Leptin; Luteinizing Hormone; Ovary; Rats, Wistar; Reproduction; Reverse Transcriptase Polymerase Chain Reaction; Topiramate | 2014 |
Simultaneous analysis of 22 antiepileptic drugs in postmortem blood, serum and plasma using LC-MS-MS with a focus on their role in forensic cases.
Topics: Amines; Anticonvulsants; Carbamazepine; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Limit of Detection; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tiagabine; Topiramate; Triazines; Valproic Acid | 2014 |
Efficacy and safety of gabapentin for uremic pruritus and restless legs syndrome in conservatively managed patients with chronic kidney disease.
Topics: Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pruritus; Renal Insufficiency, Chronic; Restless Legs Syndrome; Retrospective Studies | 2015 |
Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methods.
Topics: Amines; Amitriptyline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cyclohexanecarboxylic Acids; Demyelinating Diseases; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Female; Gabapentin; Gait; gamma-Aminobutyric Acid; Gliosis; Hyperalgesia; Mice; Morphine; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Neuralgia; Peptide Fragments; Pertussis Toxin; Quillaja Saponins | 2014 |
The distinctive significance of analgesic drugs and olfactory stimulants on learned pain in mice.
Topics: Acetaminophen; Amines; Analgesics; Animals; Conditioning, Psychological; Cyclohexanecarboxylic Acids; Fentanyl; Fluvoxamine; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Muscarinic Antagonists; Nociceptive Pain; Odorants; Olfactory Perception; Pain Perception; Physical Stimulation; Scopolamine; Selective Serotonin Reuptake Inhibitors | 2014 |
Gabapentin reverses central hypersensitivity and suppresses medial prefrontal cortical glucose metabolism in rats with neuropathic pain.
Topics: Amines; Animals; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Fluorodeoxyglucose F18; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hyperalgesia; Male; Neuralgia; Pain Measurement; Positron-Emission Tomography; Prefrontal Cortex; Radiography; Rats; Rats, Sprague-Dawley; Tomography Scanners, X-Ray Computed | 2014 |
Anesthesia influences neuronal activity and drug effectiveness in neuropathic rats.
Topics: Action Potentials; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Morphine; Neurons; Pain Measurement; Rats; Rats, Wistar; Sciatica; Spinal Cord | 2014 |
Adenylyl cyclase subtype 1 is essential for late-phase long term potentiation and spatial propagation of synaptic responses in the anterior cingulate cortex of adult mice.
Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amines; Animals; Benzofurans; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; In Vitro Techniques; Long-Term Potentiation; Male; Mice; N-Methylaspartate; Nerve Net; Quinolines; Synaptic Transmission; Time Factors | 2014 |
Noninvasive sampling of gabapentin by reverse iontophoresis.
Topics: Amines; Animals; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Electroosmosis; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Injections, Intravenous; Iontophoresis; Models, Biological; Rats; Rats, Sprague-Dawley; Rats, Wistar; Skin | 2015 |
Pharmacovigilance in hospice/palliative care: net effect of gabapentin for neuropathic pain.
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hospice Care; Humans; Male; Middle Aged; Neuralgia; Palliative Care; Pharmacovigilance; Prospective Studies | 2015 |
Determination of a selection of anti-epileptic drugs and two active metabolites in whole blood by reversed phase UPLC-MS/MS and some examples of application of the method in forensic toxicology cases.
Topics: Amines; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Forensic Toxicology; Gabapentin; gamma-Aminobutyric Acid; Humans; Levetiracetam; Oxcarbazepine; Piracetam; Tandem Mass Spectrometry | 2015 |
Comparison of the effects of gabapentin and pregabalin on wound healing in rats.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain; Pregabalin; Rats; Rats, Wistar; Treatment Outcome; Wound Healing | 2016 |
Determination of Gabapentin in Human Plasma and Urine by Capillary Electrophoresis with Laser-Induced Fluorescence Detection.
Topics: Amines; Cyclohexanecarboxylic Acids; Electrophoresis, Capillary; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence | 2015 |
Presumptive human herpesvirus 6 myelopathy in an immunocompetent patient.
Topics: Adult; Amines; Anticonvulsants; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Herpesvirus 6, Human; Humans; Immunocompetence; Radiography; Roseolovirus Infections; Spinal Cord; Spinal Cord Diseases; Verapamil | 2015 |
Post-stroke pain hypersensitivity induced by experimental thalamic hemorrhage in rats is region-specific and demonstrates limited efficacy of gabapentin.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Intracranial Hemorrhages; Male; Pain Threshold; Rats; Rats, Sprague-Dawley; Stroke; Thalamus | 2014 |
Six cases of (severe) hypoglycaemia associated with gabapentin use in both diabetic and non-diabetic patients.
Topics: Amines; Analgesics; Blood Glucose; Cyclohexanecarboxylic Acids; Diabetes Mellitus; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoglycemia; Pain | 2015 |
Safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (sah) headache and meningismus.
Topics: Adult; Aged; Amines; Analgesics; Aneurysm, Ruptured; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Intracranial Aneurysm; Male; Meningism; Middle Aged; Retrospective Studies; Subarachnoid Hemorrhage; Treatment Outcome | 2015 |
Multimodal pain control is associated with reduced hospital stay following open abdominal hysterectomy.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Bupivacaine; Cohort Studies; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Endometrial Neoplasms; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hysterectomy; Length of Stay; Middle Aged; Morphine; Pain Management; Pain, Postoperative; Prospective Studies; Retrospective Studies; Treatment Outcome; Young Adult | 2014 |
Thrombospondin-4 and excitatory synaptogenesis promote spinal sensitization after painful mechanical joint injury.
Topics: Action Potentials; Amines; Analgesics; Animals; Arthralgia; Cyclohexanecarboxylic Acids; Excitatory Postsynaptic Potentials; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hyperalgesia; Joint Capsule; Male; Neurons; Pain Measurement; Rats; Spinal Cord; Synapses; Thrombospondins; Time Factors; Tubulin; Zygapophyseal Joint | 2015 |
Attenuation of persistent pain-related behavior by fatty acid amide hydrolase (FAAH) inhibitors in a rat model of HIV sensory neuropathy.
Topics: Amidohydrolases; Amines; Analgesics; Animals; Benzamides; Carbamates; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gabapentin; gamma-Aminobutyric Acid; HIV Envelope Protein gp120; HIV Infections; Hyperalgesia; Male; Nociception; Piperidines; Pyridines; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Recombinant Proteins; Sciatic Neuropathy | 2015 |
Decarbonylative radical coupling of α-aminoacyl tellurides: single-step preparation of γ-amino and α,β-diamino acids and rapid synthesis of gabapentin and manzacidin A.
Topics: Amines; Amino Acids; Cyclohexanecarboxylic Acids; Decarboxylation; Ethers; Free Radicals; Gabapentin; gamma-Aminobutyric Acid; Glyoxylates; Pyrimidines; Pyrroles; Stereoisomerism; Tellurium | 2015 |
Seeing the unseen: Charles Bonnet syndrome revisited.
Topics: Aged; Amines; Awareness; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hallucinations; Humans; Lorazepam; Macular Degeneration; Magnetic Resonance Imaging; Male; Syndrome; Treatment Outcome; Vision Disorders | 2015 |
Severe postherpetic neuralgia and other neuropathic pain syndromes alleviated by topical gabapentin.
Topics: Aged; Aged, 80 and over; Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Neuralgia, Postherpetic; Pain Measurement; Retrospective Studies | 2015 |
Investigation of the pruritus-induced functional activity in the rat brain using manganese-enhanced MRI.
Topics: Amines; Animals; Animals, Newborn; Brain; Brain Mapping; Capsaicin; Contrast Media; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gyrus Cinguli; Limbic System; Magnetic Resonance Imaging; Male; Manganese; Pruritus; Rats; Rats, Sprague-Dawley; Thalamus | 2015 |
[Complex regional pain syndrome type 1 after fracture of distal phalanx: case report].
Topics: Amines; Analgesics; Combined Modality Therapy; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Finger Injuries; Fractures, Bone; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain Measurement | 2014 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, Replacement, Knee; Celecoxib; Cohort Studies; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Edema; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Knee Joint; Male; Methylprednisolone; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Pain, Postoperative; Postoperative Complications; Postoperative Period; Preoperative Care; Prospective Studies; Range of Motion, Articular; Treatment Outcome; Walking | 2017 |
Treating recurrent postmenopausal vasomotor symptoms in a patient with a positive family history for breast cancer.
Topics: Aged; Amines; Breast Neoplasms; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hormone Replacement Therapy; Hot Flashes; Humans; Postmenopause; Recurrence; Treatment Failure | 2015 |
Antinociceptive synergism of gabapentin and nortriptyline in mice with partial sciatic nerve ligation.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Male; Mice; Neuralgia; Nortriptyline; Peripheral Nerve Injuries; Sciatic Nerve | 2015 |
Diabetes-induced impairments of the exocytosis process and the effect of gabapentin: the link with cholesterol level in neuronal plasma membranes.
Topics: Amines; Animals; Brain; Cell Membrane; Cholesterol; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Exocytosis; Gabapentin; gamma-Aminobutyric Acid; Male; Neurons; Rats; Rats, Wistar; Serotonin | 2015 |
Patterns of health care utilization related to initiation of amitriptyline, duloxetine, gabapentin, or pregabalin in fibromyalgia.
Topics: Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Cohort Studies; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Health Services; Humans; Male; Medication Adherence; Middle Aged; Patient Acceptance of Health Care; Pregabalin | 2015 |
In vivo two-photon imaging of structural dynamics in the spinal dorsal horn in an inflammatory pain model.
Topics: Acute Disease; Amines; Animals; Calcium Channel Blockers; Calcium Channels; Cyclohexanecarboxylic Acids; Dendrites; Disease Models, Animal; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Immunohistochemistry; Inflammation; Male; Mice, Transgenic; Microscopy, Fluorescence; Pain; Patch-Clamp Techniques; Posterior Horn Cells; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Time Factors; Time-Lapse Imaging | 2015 |
Gabapentin for management of recurrent pain in 22 nonverbal children with severe neurological impairment: a retrospective analysis.
Topics: Adolescent; Adult; Amines; Analgesics; Central Nervous System Diseases; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Long-Term Care; Male; Nonverbal Communication; Pain; Pain Measurement; Retrospective Studies; Young Adult | 2015 |
Compression of lateral antebrachial cutaneous nerve in waitresses.
Topics: Adult; Amines; Analgesics; Arthrogryposis; Cyclohexanecarboxylic Acids; Electrophysiology; Female; Follow-Up Studies; Forearm; Gabapentin; gamma-Aminobutyric Acid; Hereditary Sensory and Motor Neuropathy; Humans; Musculocutaneous Nerve; Nortriptyline; Retrospective Studies | 2015 |
Injury of primary afferent neurons may contribute to osteoarthritis induced pain: an experimental study using the collagenase model in rats.
Topics: Amines; Analgesics; Animals; Arthritis, Experimental; Calcium Channels; Calcium Channels, L-Type; Collagenases; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Male; Motor Activity; Neurons, Afferent; Nociception; Nociceptive Pain; Osteoarthritis; Rats; Rats, Wistar | 2015 |
Involvement of nitridergic and opioidergic pathways in the antinociception of gabapentin in the orofacial formalin test in mice.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pain Measurement; Signal Transduction | 2015 |
A comparison of pregabalin and gabapentin in palliative care #289.
Topics: Amines; Analgesics; Biological Availability; Costs and Cost Analysis; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Palliative Care; Pregabalin | 2015 |
Differences in cisplatin-induced mechanical allodynia in male and female mice.
Topics: Amines; Analgesics; Animals; Antineoplastic Agents; Cisplatin; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Mononeuropathies; Neuralgia; Pain Threshold; Polyneuropathies; Sex Factors; Signal Transduction; Toll-Like Receptors | 2015 |
Gabapentin dependence in a patient with opioid dependence syndrome.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Opioid-Related Disorders | 2015 |
Complete Freund's adjuvant-induced reduction of exploratory activity in a novel environment as an objective nociceptive endpoint for sub-acute inflammatory pain model in rats.
Topics: Adjuvants, Immunologic; Amines; Analgesics; Animals; Behavior, Animal; Celecoxib; Cyclohexanecarboxylic Acids; Diclofenac; Disease Models, Animal; Duloxetine Hydrochloride; Exploratory Behavior; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Ibuprofen; Male; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley | 2015 |
Multiple painful nodules and uterine leiomyomas.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Leiomyomatosis; Middle Aged; Neoplastic Syndromes, Hereditary; Skin Neoplasms; Uterine Neoplasms | 2015 |
The excitatory synaptic transmission of the nucleus of solitary tract was potentiated by chronic myocardial infarction in rats.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Excitatory Postsynaptic Potentials; Gabapentin; gamma-Aminobutyric Acid; Male; Myocardial Infarction; Neurons; Oncogene Proteins v-fos; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Spermine; Synaptophysin; Visceral Pain | 2015 |
Experience from therapeutic drug monitoring and gender aspects of gabapentin and pregabalin in clinical practice.
Topics: Adult; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Monitoring; Drug Prescriptions; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Longitudinal Studies; Male; Middle Aged; Neuralgia; Norway; Pregabalin; Retrospective Studies; Sex Characteristics | 2015 |
Peripheral neuropathies: new recommendations for neuropathic pain pharmacotherapy.
Topics: Amines; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Randomized Controlled Trials as Topic; Tramadol | 2015 |
Increased expression of HCN2 channel protein in L4 dorsal root ganglion neurons following axotomy of L5- and inflammation of L4-spinal nerves in rats.
Topics: Amines; Animals; Axotomy; Cyclohexanecarboxylic Acids; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Lectins; Neuralgia; Pain Threshold; Pyrimidines; Radiculopathy; Rats; Rats, Wistar; Reaction Time; Spinal Nerves | 2015 |
Gabapentin as an adjuvant for postoperative pain management in dogs undergoing mastectomy.
Topics: Adjuvants, Anesthesia; Amines; Analgesics; Analgesics, Opioid; Anesthesia; Animals; Cyclohexanecarboxylic Acids; Dogs; Female; Gabapentin; gamma-Aminobutyric Acid; Mastectomy; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Time Factors | 2015 |
Animal behavior case of the month. Tail chasing in a dog diagnosed as compulsive disorder.
Topics: Amines; Animals; Anticonvulsants; Behavior, Animal; Bites and Stings; Cyclohexanecarboxylic Acids; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Tail | 2015 |
An acute gabapentin fatality: a case report with postmortem concentrations.
Topics: Amines; Analgesics; Cardiovascular Diseases; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Gastrointestinal Contents; Humans; Liver; Middle Aged; Obesity; Vitreous Body | 2015 |
Pressure pain sensitivity map of multifocal nummular headache: a case report.
Topics: Adolescent; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Hyperalgesia; Neurologic Examination; Pain Threshold; Pressure; Treatment Outcome | 2015 |
Abuse and diversion of gabapentin among nonmedical prescription opioid users in Appalachian Kentucky.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kentucky; Male; Opioid-Related Disorders; Prescription Drug Diversion; Substance-Related Disorders | 2015 |
Upregulation of α₂δ-1 Calcium Channel Subunit in the Spinal Cord Contributes to Pelvic Organ Cross-Sensitization in a Rat Model of Experimentally-Induced Endometriosis.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Calcium Channels; Calcium Channels, L-Type; Chronic Pain; Cyclohexanecarboxylic Acids; Endometriosis; Female; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Immunization; Injections, Spinal; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Spinal Cord; Up-Regulation | 2015 |
Gabapentin and pregabalin: hepatic and haematological toxicity.
Topics: Amines; Analgesics; Chemical and Drug Induced Liver Injury; Cyclohexanecarboxylic Acids; France; Gabapentin; gamma-Aminobutyric Acid; Hematologic Diseases; Humans; Pharmacovigilance; Pregabalin; Severity of Illness Index | 2014 |
Clinical trials supported by the Tinnitus Research Consortium: Lessons learned, the Southern Illinois University experience.
Topics: Amines; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Illinois; Loudness Perception; Psychometrics; Research Support as Topic; Surveys and Questionnaires; Tinnitus; Universities | 2016 |
Antinociceptive and hypnotic activities of pregabalin in a neuropathic pain-like model in mice.
Topics: Amines; Analgesics; Animals; Cerebral Cortex; Cyclohexanecarboxylic Acids; Electroencephalography; Gabapentin; gamma-Aminobutyric Acid; Genes, fos; Hot Temperature; Hyperalgesia; Hypnotics and Sedatives; Male; Mice; Mice, Inbred C57BL; Neuralgia; Pain Measurement; Physical Stimulation; Postural Balance; Pregabalin; Sciatic Neuropathy; Sleep Wake Disorders; Sleep, REM | 2015 |
Gabapentin inhibits the activity of the rat excitatory glutamate transporter 3 expressed in Xenopus oocytes.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Transporter 3; Female; Gabapentin; gamma-Aminobutyric Acid; Gene Expression; Oocytes; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Rats; Xenopus laevis | 2015 |
Nanosponge-based pediatric-controlled release dry suspension of Gabapentin for reconstitution.
Topics: Administration, Oral; Adult; Amines; Animals; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Nanoparticles; Rats; Rats, Wistar; Suspensions; Taste; X-Ray Diffraction; Young Adult | 2015 |
Gabapentin alleviates affective pain after traumatic nerve injury.
Topics: Affect; Amines; Analgesics; Animals; Conditioning, Psychological; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Neuralgia; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2015 |
Chronic progressive polyarthritis in a domestic shorthair cat.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Buprenorphine; Cat Diseases; Cats; Chronic Disease; Cyclohexanecarboxylic Acids; Cyclosporine; Gabapentin; gamma-Aminobutyric Acid; Immunosuppressive Agents; Male; Pain; Prednisolone; Retroviridae Infections; Spumavirus | 2015 |
Gabapentin Treatment in Bruxism Associated With Fluoxetine.
Topics: Adult; Amines; Bruxism; Cyclohexanecarboxylic Acids; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Humans; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 2015 |
The Effect of a Novel form of Extended-Release Gabapentin on Pain and Sleep in Fibromyalgia Subjects: An Open-Label Pilot Study.
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Endpoint Determination; Female; Fibromyalgia; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain; Pain Measurement; Pilot Projects; Prospective Studies; Quality of Life; Sleep Wake Disorders; Surveys and Questionnaires | 2016 |
Psychotic and depressive symptoms after gabapentin treatment.
Topics: Amines; Cyclohexanecarboxylic Acids; Depression; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Psychoses, Substance-Induced | 2015 |
Spontaneous Chronic Pain After Experimental Thoracotomy Revealed by Conditioned Place Preference: Morphine Differentiates Tactile Evoked Pain From Spontaneous Pain.
Topics: Amines; Analgesics; Analysis of Variance; Animals; Conditioning, Operant; Cyclohexanecarboxylic Acids; Disease Models, Animal; Evoked Potentials; Gabapentin; gamma-Aminobutyric Acid; Male; Morphine; Pain Threshold; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Ribs; Statistics as Topic; Thoracotomy; Time Factors; Touch | 2015 |
Suboptimal Treatment of Diabetic Peripheral Neuropathic Pain in the United States.
Topics: Adult; Aged; Amines; Antidepressive Agents; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pregabalin; Quality of Life; Retrospective Studies; Treatment Outcome; United States | 2015 |
A streptozotocin-induced diabetic neuropathic pain model for static or dynamic mechanical allodynia and vulvodynia: validation using topical and systemic gabapentin.
Topics: Administration, Topical; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections; Neuralgia; Rats, Sprague-Dawley; Vulvodynia | 2015 |
Development of a cell-based screening method for compounds that inhibit or are transported by large neutral amino acid transporter 1, a key transporter at the blood-brain barrier.
Topics: Amines; Biological Transport; Blood-Brain Barrier; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; HT29 Cells; Humans; Large Neutral Amino Acid-Transporter 1; Mass Spectrometry | 2015 |
Routine prescribing of gabapentin or pregabalin in supportive and palliative care: what are the comparative performances of the medications in a palliative care population?
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug Prescriptions; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Neuralgia; Pain Measurement; Palliative Care; Pregabalin | 2015 |
Effect of carbamazepine and gabapentin on excitability in the trigeminal subnucleus caudalis of neonatal rats using a voltage-sensitive dye imaging technique.
Topics: Action Potentials; Afferent Pathways; Amines; Animals; Animals, Newborn; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Rats; Rats, Wistar; Trigeminal Neuralgia; Trigeminal Nucleus, Spinal; Voltage-Sensitive Dye Imaging | 2015 |
[Shingles symptoms are gone but not the pain].
Topics: Administration, Cutaneous; Administration, Oral; Aged; Amines; Amitriptyline; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cyclohexanecarboxylic Acids; Dipyrone; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Guideline Adherence; Humans; Ibuprofen; Lidocaine; Neuralgia, Postherpetic; Phenols; Pregabalin; Tapentadol; Treatment Failure | 2015 |
Spontaneous reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Databases, Factual; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Male; Middle Aged; Oxcarbazepine; Pharmacovigilance; Phenobarbital; Spain; Stevens-Johnson Syndrome; Triazines; Valproic Acid; Young Adult | 2015 |
R-phenibut binds to the α2-δ subunit of voltage-dependent calcium channels and exerts gabapentin-like anti-nociceptive effects.
Topics: Amines; Analgesics; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Male; Mice, Inbred ICR; Pain Measurement; Protein Binding; Rats; Rats, Wistar | 2015 |
Effect of a Novel, Orally Active Matrix Metalloproteinase-2 and -9 Inhibitor in Spinal and Trigeminal Rat Models of Neuropathic Pain.
Topics: Administration, Oral; Amines; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Indoles; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Neuralgia; Propionates; Rats; Rats, Sprague-Dawley; Spinal Nerves; Thiophenes; Trigeminal Nerve | 2015 |
Neonatal Gabapentin Withdrawal Syndrome.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Neonatal Abstinence Syndrome; Treatment Outcome | 2015 |
Identification of phototransformation products of the antiepileptic drug gabapentin: Biodegradability and initial assessment of toxicity.
Topics: Amines; Anticonvulsants; Bacteria; Biodegradation, Environmental; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Luminescence; Mutagenicity Tests; Photolysis; Toxicity Tests, Acute; Ultraviolet Rays; Water Pollutants, Chemical | 2015 |
Separate and combined effects of gabapentin and [INCREMENT]9-tetrahydrocannabinol in humans discriminating [INCREMENT]9-tetrahydrocannabinol.
Topics: Amines; Analysis of Variance; Blood Pressure; Body Temperature; Cyclohexanecarboxylic Acids; Discrimination Learning; Dronabinol; Drug Combinations; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Humans; Male; Marijuana Abuse; Outcome Assessment, Health Care; Psychomotor Performance; Surveys and Questionnaires; Visual Analog Scale | 2016 |
Pharmacological characteristics of the hind paw weight bearing difference induced by chronic constriction injury of the sciatic nerve in rats.
Topics: Amines; Analgesics; Animals; Chronic Disease; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Male; Nerve Compression Syndromes; Rats; Sciatic Nerve; Sciatic Neuropathy; Weight-Bearing | 2009 |
Gabapentin, an Analgesic Used Against Cancer-Associated Neuropathic Pain: Effects on Prostate Cancer Progression in an In Vivo Rat Model.
Topics: Amines; Analgesics; Animals; Carcinogenesis; Cells, Cultured; Cyclohexanecarboxylic Acids; Disease Models, Animal; Disease Progression; Gabapentin; gamma-Aminobutyric Acid; Lung Neoplasms; Male; Neuralgia; Prostatic Neoplasms; Rats | 2016 |
Evaluation of the Percutaneous Absorption of Ketamine HCl, Gabapentin, Clonidine HCl, and Baclofen, in Compounded Transdermal Pain Formulations, Using the Franz Finite Dose Model.
Topics: Administration, Cutaneous; Aged; Amines; Baclofen; Clonidine; Cyclohexanecarboxylic Acids; Drug Compounding; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Middle Aged; Organ Culture Techniques; Pain; Skin Absorption | 2016 |
PHARMACOKINETIC PROPERTIES OF A SINGLE ADMINISTRATION OF ORAL GABAPENTIN IN THE GREAT HORNED OWL (BUBO VIRGINIANUS).
Topics: Amines; Analgesics; Animals; Area Under Curve; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Strigiformes | 2015 |
[The principles of pharmacotherapy of poststroke shoulder pain].
Topics: Amines; Amitriptyline; Anti-Inflammatory Agents; Clonidine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Male; Pregabalin; Shoulder Pain; Stroke | 2015 |
Enigmatic Fever and Delirium in a Critically Ill Patient.
Topics: Adult; Amines; Critical Illness; Cyclohexanecarboxylic Acids; Delirium; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Intensive Care Units; Male; Substance Withdrawal Syndrome | 2015 |
Pharmacokinetics of Compounded Intravenous and Oral Gabapentin in Hispaniolan Amazon Parrots ( Amazona ventralis ).
Topics: Administration, Oral; Amazona; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Injections, Intravenous | 2015 |
THROMBOCYTOPENIA WITH GABAPENTIN USAGE.
Topics: Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsies, Partial; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Thrombocytopenia | 2015 |
Gabapentin attenuates neuropathic pain and improves nerve myelination after chronic sciatic constriction in rats.
Topics: Amines; Animals; Anticonvulsants; Constriction, Pathologic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Male; Myelin Basic Protein; Nerve Regeneration; Neuralgia; Rats, Wistar; Sciatic Nerve | 2015 |
Long-term cost-effectiveness of initiating treatment for painful diabetic neuropathy with pregabalin, duloxetine, gabapentin, or desipramine.
Topics: Amines; Analgesics; Cost-Benefit Analysis; Cyclohexanecarboxylic Acids; Desipramine; Diabetic Neuropathies; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Health Care Costs; Humans; Models, Economic; Pregabalin; Quality-Adjusted Life Years | 2016 |
5-HT6 receptor antagonist attenuates the memory deficits associated with neuropathic pain and improves the efficacy of gabapentinoids.
Topics: Amines; Animals; Cognition; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Memory Disorders; Neuralgia; Pregabalin; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists | 2015 |
Quantitative target and systematic non-target analysis of polar organic micro-pollutants along the river Rhine using high-resolution mass-spectrometry--Identification of unknown sources and compounds.
Topics: Amines; Clonidine; Cyclohexanecarboxylic Acids; Europe; Gabapentin; gamma-Aminobutyric Acid; Imidazoles; Mass Spectrometry; Metformin; Pesticides; Pharmaceutical Preparations; Rivers; Seasons; Solid Phase Extraction; Thiazines; Wastewater; Water Pollutants, Chemical; Water Pollution, Chemical | 2015 |
A Medication Combination for the Treatment of Central Poststroke Pain via the Adjuvant Use of Prednisone With Gabapentin: A Case Report.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Humans; Magnetic Resonance Imaging; Neuralgia; Pain Management; Prednisone; Stroke | 2016 |
Gabapentin potentiates sensitivity to the interoceptive effects of alcohol and increases alcohol self-administration in rats.
Topics: Alcohol Drinking; Alcohols; Amines; Analgesics; Analysis of Variance; Animals; Central Nervous System Depressants; Conditioning, Operant; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Male; Motor Activity; Rats; Rats, Long-Evans; Reinforcement, Psychology; Self Administration; Sucrose | 2016 |
Predicting Neuroinflammation in Morphine Tolerance for Tolerance Therapy from Immunostaining Images of Rat Spinal Cord.
Topics: Amines; Analgesics, Opioid; Animals; Astrocytes; Cyclohexanecarboxylic Acids; Drug Tolerance; Gabapentin; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Microglia; Morphine; Neurons; Pain Measurement; Rats; Rats, Wistar; Spinal Cord; Support Vector Machine | 2015 |
Gabapentin can significantly improve dystonia severity and quality of life in children.
Topics: Activities of Daily Living; Adolescent; Amines; Child; Cyclohexanecarboxylic Acids; Disability Evaluation; Dystonia; Dystonic Disorders; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Quality of Life; Retrospective Studies | 2016 |
Peripheral Neuritis Trauma in Pigs: A Neuropathic Pain Model.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Calcitonin Gene-Related Peptide; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Morphine; Motor Activity; Neuralgia; Pain Measurement; Physical Stimulation; Swine | 2016 |
Caffeine prevents antihyperalgesic effect of gabapentin in an animal model of CRPS-I: evidence for the involvement of spinal adenosine A1 receptor.
Topics: Amines; Analgesics; Animals; Caffeine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Mice; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A1; Reflex Sympathetic Dystrophy; Spinal Cord | 2015 |
Leg kicking and rubbing as a highly suggestive sign of pediatric restless legs syndrome.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Restless Legs Syndrome | 2015 |
Gabapentin Effects on PKC-ERK1/2 Signaling in the Spinal Cord of Rats with Formalin-Induced Visceral Inflammatory Pain.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amines; Animals; Behavior, Animal; Cell Membrane; Cyclohexanecarboxylic Acids; Disease Models, Animal; Electrophysiological Phenomena; Flavonoids; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; MAP Kinase Signaling System; Neurons; Pain Management; Phosphorylation; Protein Kinase C; Protein Transport; Rats; Spinal Cord; Visceral Pain | 2015 |
The effect of gabapentin and ketorolac on allodynia and conditioned place preference in antibody-induced inflammation.
Topics: Amines; Analgesics; Animals; Arthritis; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Glucose-6-Phosphate Isomerase; Hyperalgesia; Ketorolac; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL | 2016 |
Trigeminal neuropathic pain as a complication of anterior temporal lobectomy: report of 2 cases.
Topics: Amines; Analgesics; Anterior Temporal Lobectomy; Cyclohexanecarboxylic Acids; Drug Resistant Epilepsy; Electroencephalography; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain, Postoperative; Treatment Outcome; Trigeminal Neuralgia | 2016 |
First Bite Syndrome After Bilateral Temporomandibular Joint Replacement: Case Report.
Topics: Adult; Amines; Analgesics; Arthroplasty, Replacement; Cyclohexanecarboxylic Acids; Facial Pain; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Joint Prosthesis; Mastication; Pain, Postoperative; Parotid Region; Surgical Flaps; Temporal Muscle; Temporomandibular Joint; Temporomandibular Joint Disc; Temporomandibular Joint Disorders | 2016 |
Prediction of quality of life improvements in patients with lumbar stenosis following use of membrane stabilizing agents.
Topics: Aged; Aged, 80 and over; Amines; Calcium Channel Blockers; Comorbidity; Cyclohexanecarboxylic Acids; Decision Support Techniques; Decompression, Surgical; Depression; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Income; Lumbar Vertebrae; Male; Marital Status; Middle Aged; Nomograms; Pregabalin; Proportional Hazards Models; Quality of Life; Retrospective Studies; Risk Factors; Spinal Stenosis | 2015 |
Integrating multiple data sources (MUDS) for meta-analysis to improve patient-centered outcomes research: a protocol.
Topics: Amines; Analgesics; Antipsychotic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; Data Interpretation, Statistical; Gabapentin; gamma-Aminobutyric Acid; Humans; Meta-Analysis as Topic; Neuralgia; Outcome Assessment, Health Care; Patient-Centered Care; Quetiapine Fumarate; Research Design; Selection Bias; Systematic Reviews as Topic | 2015 |
A cause for craniocervical pain.
Topics: Aged, 80 and over; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Imaging, Three-Dimensional; Neck Pain; Ossification, Heterotopic; Temporal Bone; Tomography, X-Ray Computed | 2016 |
[Clinical effects of gabapentin on the treatment of pruritus of scar resulting from deep partial-thickness burn].
Topics: Amines; Analgesics; Ascorbic Acid; Burns; Cetirizine; Cicatrix; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pruritus; Skin Transplantation; Treatment Outcome; Visual Analog Scale; Wound Healing | 2015 |
Gabapentin Use in the Neonatal Intensive Care Unit.
Topics: Amines; Analgesics; Benzodiazepines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Infant, Newborn; Intensive Care Units, Neonatal; Male; Retrospective Studies | 2016 |
[On the Differential Diagnosis of Intractable Psychogenic Chronic Cough: Neuropathic Larynx Irritable - Gabapentin's Antitussive Action].
Topics: Aged; Amines; Avitaminosis; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Depressive Disorder, Major; Diagnosis, Differential; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Glucose Intolerance; Goiter; Humans; Larynx; Peripheral Nervous System Diseases; Pharynx; Psychophysiologic Disorders | 2015 |
Topical ambroxol for the treatment of neuropathic pain. An initial clinical observation.
Topics: Administration, Topical; Adult; Aged; Ambroxol; Amines; Anesthetics, Local; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Retrospective Studies | 2015 |
Antinociceptive Grayanoids from the Roots of Rhododendron molle.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Diterpenes; Drugs, Chinese Herbal; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Molecular Structure; Morphine; Nuclear Magnetic Resonance, Biomolecular; Pain; Plant Roots; Rhododendron | 2015 |
Co-administration of morphine and gabapentin leads to dose dependent synergistic effects in a rat model of postoperative pain.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Morphine; Pain, Postoperative; Physical Stimulation; Rats, Sprague-Dawley | 2016 |
Homology modelling and molecular docking studies of human placental cadherin protein for its role in teratogenic effects of anti-epileptic drugs.
Topics: Acetamides; Amines; Animals; Anticonvulsants; Binding Sites; Cadherins; Calcium; Cations, Divalent; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Pregabalin; Pregnancy; Sequence Homology; Teratogens; Vigabatrin | 2016 |
Pharmacological characterization of intraplantar Complete Freund's Adjuvant-induced burrowing deficits.
Topics: Amines; Analgesics; Animals; Antibodies; Behavior, Animal; Celecoxib; Cyclohexanecarboxylic Acids; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Ibuprofen; Indomethacin; Inflammation; Male; Morphine; Motor Activity; Nerve Growth Factor; Pain; Rats, Wistar; Tramadol | 2016 |
Effect of levetiracetam versus gabapentin on peripheral neuropathy and sciatic degeneration in streptozotocin-diabetic mice: Influence on spinal microglia and astrocytes.
Topics: Amines; Animals; Astrocytes; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Levetiracetam; Male; Mice; Microglia; Nerve Degeneration; Nootropic Agents; Pain Measurement; Piracetam; Sciatic Neuropathy; Spinal Cord | 2016 |
Utilization of a Preemptive, Multimodal Analgesic Regimen in Adult Ambulatory Septoplasty Patients: A Quality Improvement Project.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Amines; Analgesics; Celecoxib; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hospitals, Community; Humans; Nasal Septum; Pain, Postoperative; Postoperative Nausea and Vomiting; Preoperative Care; Quality Improvement | 2015 |
Involvement of NO/cGMP pathway in the antidepressant-like effect of gabapentin in mouse forced swimming test.
Topics: Amines; Animals; Antidepressive Agents; Behavior, Animal; Cyclic GMP; Cyclohexanecarboxylic Acids; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Guanylate Cyclase; Hippocampus; Male; Motor Activity; Nitric Oxide; Nitric Oxide Synthase Type I; Phosphodiesterase 5 Inhibitors; Signal Transduction; Swimming | 2016 |
Predictive Factors for Prophylactic Percutaneous Endoscopic Gastrostomy (PEG) Tube Placement and Use in Head and Neck Patients Following Intensity-Modulated Radiation Therapy (IMRT) Treatment: Concordance, Discrepancies, and the Role of Gabapentin.
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Deglutition Disorders; Enteral Nutrition; Female; Gabapentin; gamma-Aminobutyric Acid; Gastroscopy; Gastrostomy; Head and Neck Neoplasms; Humans; Intubation, Gastrointestinal; Logistic Models; Male; Middle Aged; Multivariate Analysis; Prophylactic Surgical Procedures; Radiotherapy, Intensity-Modulated; Retrospective Studies; Sex Factors | 2016 |
Chronic refractory myofascial pain and denervation supersensitivity as global public health disease.
Topics: Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Denervation; Electric Stimulation Therapy; Gabapentin; gamma-Aminobutyric Acid; Humans; Low Back Pain; Male; Middle Aged; Myofascial Pain Syndromes; Pain Measurement; Public Health; Radiculopathy | 2016 |
Pharmacokinetic/Pharmacodynamic Relationship of Gabapentin in a CFA-induced Inflammatory Hyperalgesia Rat Model.
Topics: Amines; Analgesics; Animals; Biological Availability; Brain; Computer Simulation; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Models, Biological; Rats; Rats, Sprague-Dawley | 2016 |
Gabapentinoid Insensitivity after Repeated Administration is Associated with Down-Regulation of the α(2)δ-1 Subunit in Rats with Central Post-Stroke Pain Hypersensitivity.
Topics: Amines; Analgesics; Animals; Blotting, Western; Calcium Channels; Cyclohexanecarboxylic Acids; Disease Models, Animal; Down-Regulation; Drug Tolerance; Fluorescent Antibody Technique; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Neuralgia; Neurons; Rats; Rats, Sprague-Dawley; Stroke; Thalamus | 2016 |
Analysis of the behavioral, cellular and molecular characteristics of pain in severe rodent spinal cord injury.
Topics: Amines; Animals; Calcitonin Gene-Related Peptide; Calcium-Binding Proteins; Carbenoxolone; Connexin 43; Cyclohexanecarboxylic Acids; Disease Models, Animal; Escape Reaction; Female; Forelimb; Gabapentin; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Hyperalgesia; Lectins; Microfilament Proteins; Motor Activity; Pain; Pain Measurement; Rats; Rats, Inbred F344; Spinal Cord; Spinal Cord Injuries; Tubulin | 2016 |
Calcium Imaging of Neuronal Activity in Drosophila Can Identify Anticonvulsive Compounds.
Topics: 4-Aminopyridine; Adult; Amines; Animals; Anticonvulsants; Antipain; Calcium; Calmodulin; Central Nervous System; Convulsants; Cyclohexanecarboxylic Acids; Dipyridamole; Drosophila melanogaster; Drosophila Proteins; Female; Gabapentin; gamma-Aminobutyric Acid; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Larva; Male; Molecular Imaging; Motor Neurons; Phenytoin; Picrotoxin; Primary Cell Culture; Sodium Channels | 2016 |
Antinociceptive Interaction of Tramadol with Gabapentin in Experimental Mononeuropathic Pain.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Interleukin-1beta; Linear Models; Male; Mice; Mononeuropathies; Neuralgia; Tramadol | 2016 |
Abuse of Gabapentin is Associated with Opioid Addiction.
Topics: Adult; Amines; Attention Deficit Disorder with Hyperactivity; Comorbidity; Criminals; Cyclohexanecarboxylic Acids; Depressive Disorder; Diagnosis, Dual (Psychiatry); Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Mental Disorders; Middle Aged; Opioid-Related Disorders; Prescription Drug Misuse; Substance-Related Disorders; Surveys and Questionnaires; United States | 2016 |
Optical isomers of phenibut inhibit [H(3)]-Gabapentin binding in vitro and show activity in animal models of chronic pain.
Topics: Amines; Animals; Chronic Pain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Hypersensitivity; Male; Pain Measurement; Radioligand Assay; Rats; Stereoisomerism | 2016 |
THC:CBD Observational Study Data: Evolution of Resistant MS Spasticity and Associated Symptoms.
Topics: Adult; Amines; Baclofen; Calcium Channel Blockers; Cannabidiol; Cohort Studies; Cyclohexanecarboxylic Acids; Dronabinol; Drug Combinations; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Humans; Italy; Male; Medical Marijuana; Middle Aged; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Observational Studies as Topic; Oral Sprays; Plant Extracts; Pregabalin; Prospective Studies; Treatment Outcome | 2016 |
Auriculotemporal Neuralgia: Eight New Cases Report.
Topics: Adult; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Facial Pain; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nerve Block; Neuralgia | 2016 |
Amitriptyline and carbamazepine utilize voltage-gated ion channel suppression to impair excitability of sensory dorsal horn neurons in thin tissue slice: An in vitro study.
Topics: Amines; Amitriptyline; Analgesics; Animals; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Posterior Horn Cells; Potassium Channels, Voltage-Gated; Protein Isoforms; Rats; Sensory Receptor Cells; Voltage-Gated Sodium Channels | 2016 |
Painless legs and moving toes syndrome associated with a sacral Tarlov cyst: a case report.
Topics: Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Dyskinesias; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Leg; Magnetic Resonance Imaging; Middle Aged; Pain; Radiculopathy; Sacrum; Syndrome; Toes; Treatment Outcome | 2016 |
[Postmastectomy pain syndrome in our region: characteristics, treatment, and experience with gabapentin].
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mastectomy; Middle Aged; Neuralgia; Pain, Postoperative; Retrospective Studies | 2016 |
Spinal activity of interleukin 6 mediates myelin basic protein-induced allodynia.
Topics: Amines; Animals; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Cyclooxygenase Inhibitors; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Genomics; Hyperalgesia; Interleukin-6; Ketorolac; Lidocaine; Myelin Basic Protein; Peptide Fragments; Rats; Rats, Nude; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Voltage-Gated Sodium Channel Blockers | 2016 |
IV and V cranial nerves dysfunction as initial manifestations of superficial siderosis of the central nervous system.
Topics: Aged; Amines; Angiography, Digital Subtraction; Atrophy; Central Nervous System Diseases; Cerebellum; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hearing Loss, Sensorineural; Hemosiderosis; Humans; Magnetic Resonance Imaging; Male; Subarachnoid Hemorrhage; Tomography, X-Ray Computed; Trigeminal Nerve Diseases; Trochlear Nerve Diseases | 2016 |
Effect of topical neuromodulatory medications on oral and skin keratinocytes.
Topics: Administration, Topical; Amines; Amitriptyline; Analgesics; Carbamazepine; Cell Line; Cell Survival; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Keratinocytes; Mouth; Skin; Toxicity Tests | 2017 |
Management of Peripheral Entrapment Neuropathy Following Abdominoplasty: A Case Report.
Topics: Abdominal Pain; Abdominoplasty; Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Nerve Compression Syndromes; Postoperative Complications | 2016 |
Development and validation of a stability-indicating RP-HPL C-CAD method for gabapentin and its related impurities in presence of degradation products.
Topics: Amines; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Spectrometry, Mass, Electrospray Ionization | 2016 |
Thinking Outside the Box.
Topics: Abdominal Pain; Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Magnetic Resonance Imaging; Male; Nerve Compression Syndromes; Pain Measurement; Thoracic Vertebrae; Treatment Outcome | 2016 |
Gabapentin concentrations and postmortem distribution.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Liver; Male; Middle Aged; Postmortem Changes; Tissue Distribution | 2016 |
Antinociceptive Interactions Between Meloxicam and Gabapentin in Neuropathic Pain Depend on the Ratio used in Combination in Rats.
Topics: Amines; Analgesics; Animals; Area Under Curve; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Male; Meloxicam; Neuralgia; Rats; Thiazines; Thiazoles; Treatment Outcome | 2016 |
Macular Edema after Gabapentin.
Topics: Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Fluorescein Angiography; Gabapentin; gamma-Aminobutyric Acid; Humans; Macular Edema; Male; Neuralgia; Tomography, Optical Coherence; Vision Disorders; Visual Acuity | 2016 |
Continuous chest wall ropivacaine infusion for analgesia in children undergoing Nuss procedure: a comparison with thoracic epidural.
Topics: Adolescent; Amides; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, Epidural; Anesthetics, Local; Clonidine; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Female; Funnel Chest; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusions, Parenteral; Male; Morphine; Pain, Postoperative; Retrospective Studies; Ropivacaine; Thoracic Wall | 2016 |
Structural and morphological diversity of self-assembled synthetic γ-amino acid containing peptides.
Topics: Amines; Amino Acids; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen Bonding; Models, Molecular; Molecular Structure; Oligopeptides; Particle Size; Surface Properties | 2016 |
Analgesic drugs and the gut - a reciprocal relationship.
Topics: Acetaminophen; Administration, Oral; Amines; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Cyclohexanecarboxylic Acids; Digestive System Diseases; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Selective Serotonin Reuptake Inhibitors | 2015 |
Thrombospondin-4 reduces binding affinity of [(3)H]-gabapentin to calcium-channel α2δ-1-subunit but does not interact with α2δ-1 on the cell-surface when co-expressed.
Topics: Amines; Analgesics; Calcium Channels; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Immunoprecipitation; Protein Binding; Thrombospondins | 2016 |
Influence of caffeine on the protective activity of gabapentin and topiramate in a mouse model of generalized tonic-clonic seizures.
Topics: Amines; Animals; Anticonvulsants; Caffeine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Fructose; Gabapentin; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Memory, Long-Term; Mice; Motor Skills; Seizures; Topiramate | 2016 |
Newborn with severe epidermolysis bullosa: to treat or not to treat?
Topics: Amines; Blister; Chronic Pain; Cyclohexanecarboxylic Acids; Epidermolysis Bullosa; Epidermolysis Bullosa, Junctional; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Male; Nutritional Support; Pain Management; Severity of Illness Index; Skin | 2016 |
Visual hallucinations associated with gabapentin use.
Topics: Aged; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hallucinations; Humans | 2016 |
Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia.
Topics: Amines; Analgesics; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain Ischemia; Carbamazepine; Chemotherapy, Adjuvant; Cyclohexanecarboxylic Acids; Cyclopropanes; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Imipramine; Indomethacin; Male; Mexiletine; Mice; Milnacipran; Morphine; Neuralgia; Paroxetine; Selective Serotonin Reuptake Inhibitors | 2016 |
Gabapentin prevents behavioral changes on the amphetamine-induced animal model of schizophrenia.
Topics: Amines; Amphetamine; Animals; Behavior, Animal; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Humans; Models, Animal; Rats, Sprague-Dawley; Schizophrenia | 2016 |
[A case of painful legs and moving toes syndrome treated with gabapentin].
Topics: Administration, Oral; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain, Intractable; Restless Legs Syndrome; Toes | 2016 |
Medial plantar nerve ligation as a novel model of neuropathic pain in mice: pharmacological and molecular characterization.
Topics: Activating Transcription Factor 3; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation; Humans; Hyperalgesia; Interleukin-6; Ligation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neuralgia; Neuroglia; Sensory Receptor Cells; Spinal Cord; Tibial Nerve; Tumor Necrosis Factor-alpha | 2016 |
Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test.
Topics: Amines; Analgesics; Animals; Calcium Channels; Casein Kinase I; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Male; Mechanotransduction, Cellular; Mice; Pyrimidines; Quantitative Trait Loci; rab GTP-Binding Proteins; Sensory Thresholds; Touch | 2016 |
Vitamin C enhances the analgesic effect of gabapentin on rats with neuropathic pain.
Topics: Amines; Analgesics; Animals; Ascorbic Acid; Cyclohexanecarboxylic Acids; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Male; Neuralgia; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2016 |
Therapeutic Implications of Peripheral Nerve Hyperexcitability in Muscle Cramping: A Retrospective Review.
Topics: Amines; Analgesics, Non-Narcotic; Antibodies; Carbamazepine; Cyclohexanecarboxylic Acids; Electric Stimulation Therapy; Electrodiagnosis; Electromyography; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Muscle Cramp; Peripheral Nervous System Diseases; Potassium Channels, Voltage-Gated; Retrospective Studies | 2016 |
Commentary on Smith et al. (2016): Gabapentin-looks like a drug that can be misused…, probably is a drug that can be misused.
Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans | 2016 |
Comment: Gabapentin: Abuse, Dependence, and Withdrawal.
Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Substance Withdrawal Syndrome | 2016 |
Clinical Inquiry: Which nonhormonal treatments are effective for hot flashes?
Topics: Amines; Antidepressive Agents; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Isoflavones; Menopause; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors | 2016 |
The Antinociceptive Effects of Tramadol and/or Gabapentin on Rat Neuropathic Pain Induced by a Chronic Constriction Injury.
Topics: Amines; Analgesics; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Lethal Dose 50; Male; Mice; Neuralgia; Rats; Rats, Wistar; Tramadol | 2016 |
A Decade of Gabapentinoid Misuse: An Analysis of the European Medicines Agency's 'Suspected Adverse Drug Reactions' Database.
Topics: Adult; Amines; Analgesics, Opioid; Behavior, Addictive; Cyclohexanecarboxylic Acids; Databases, Factual; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pregabalin; Prescription Drug Misuse; Substance-Related Disorders | 2016 |
Gabapentin loses efficacy over time after nerve injury in rats: role of glutamate transporter-1 in the locus coeruleus.
Topics: Amines; Analgesics; Animals; Antihypertensive Agents; Atropine; Bronchodilator Agents; Clonidine; CREB-Binding Protein; Cyclohexanecarboxylic Acids; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Gabapentin; gamma-Aminobutyric Acid; Locus Coeruleus; Male; Norepinephrine; Pain Threshold; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Spinal Cord Dorsal Horn; Time Factors | 2016 |
Clinical and economic consequences of treating patients with peripheral neuropathic pain with brand name or generic drugs in routine clinical practice: The effects of age and sex.
Topics: Aged; Amines; Analgesics; Cyclohexanecarboxylic Acids; Drugs, Generic; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Retrospective Studies | 2018 |
Reply: Gabapentin: Abuse, Dependence, and Withdrawal.
Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Substance Withdrawal Syndrome | 2016 |
A novel Schiff base derived from the gabapentin drug and copper (II) complex: Synthesis, characterization, interaction with DNA/protein and cytotoxic activity.
Topics: Amines; Antineoplastic Agents; Cell Line, Tumor; Copper; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; DNA; Drug Screening Assays, Antitumor; Gabapentin; gamma-Aminobutyric Acid; Humans; Ligands; Mass Spectrometry; Proteins; Schiff Bases; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 2016 |
Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain.
Topics: Amines; Animals; Behavior, Animal; Cathepsins; Cyclohexanecarboxylic Acids; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Male; Mice; Neuralgia; Pregabalin; Protease Inhibitors | 2016 |
L503F variant of carnitine/organic cation transporter 1 efficiently transports metformin and other biguanides.
Topics: Amines; Asian People; Biguanides; Biological Transport, Active; Buformin; Carnitine; Cyclohexanecarboxylic Acids; Ergothioneine; Gabapentin; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Intestinal Absorption; Metformin; Organic Cation Transporter 1; Polymorphism, Single Nucleotide; White People | 2016 |
Population Pharmacokinetic Modelling of Morphine, Gabapentin and their Combination in the Rat.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Drug Interactions; Enterohepatic Circulation; Gabapentin; gamma-Aminobutyric Acid; Glucuronides; Models, Biological; Morphine; Nonlinear Dynamics; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2016 |
A case of gabapentin-induced rhabdomyolysis requiring renal replacement therapy.
Topics: Adult; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Renal Dialysis; Renal Replacement Therapy; Rhabdomyolysis | 2017 |
FUS-linked essential tremor associated with motor dysfunction in Drosophila.
Topics: Amines; Animals; Animals, Genetically Modified; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dopaminergic Neurons; Drosophila melanogaster; Essential Tremor; GABAergic Neurons; Gabapentin; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; Humans; Longevity; Motor Disorders; Mutation; Organ Specificity; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; RNA-Binding Protein FUS; Serotonergic Neurons | 2016 |
Immediate and delayed treatment with gabapentin, carbamazepine and CNQX have almost similar impact on cognitive functions and behavior in the lithium-pilocarpine model in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amines; Animals; Behavior, Animal; Carbamazepine; Cognition; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Lithium; Male; Maze Learning; Motor Activity; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2016 |
Multilevel symmetric neuropathic pruritus (MSNP) presenting as recalcitrant "generalized" pruritus.
Topics: Age Distribution; Aged; Amines; Chronic Disease; Cohort Studies; Cyclohexanecarboxylic Acids; Disease Progression; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Incidence; Male; Middle Aged; Peripheral Nervous System Diseases; Prognosis; Pruritus; Quality of Life; Retrospective Studies; Risk Assessment; Severity of Illness Index; Sex Distribution | 2016 |
Recruitment methods in a clinical trial of provoked vulvodynia: Predictors of enrollment.
Topics: Adult; Age Factors; Amines; Analgesics; Black or African American; Clinical Trials as Topic; Community-Institutional Relations; Cyclohexanecarboxylic Acids; Educational Status; Ethnicity; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Income; Marital Status; Mass Media; Middle Aged; Patient Selection; Postal Service; Racial Groups; Socioeconomic Factors; Vulvodynia; White People | 2017 |
Identification, synthesis, isolation and characterization of formulation related impurity of Gabapentin.
Topics: Amines; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Drug Contamination; Excipients; Gabapentin; gamma-Aminobutyric Acid; Lactose; Maillard Reaction | 2016 |
Potential Contribution of Antioxidant Mechanism in the Defensive Effect of Lycopene Against Partial Sciatic Nerve Ligation Induced Behavioral, Biochemical and Histopathological Modification in Wistar Rats.
Topics: Amines; Animals; Antioxidants; Carotenoids; Catalase; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutathione; Hyperalgesia; Ligation; Lipid Peroxidation; Lycopene; Male; Neuralgia; Oxidative Stress; Pain Measurement; Rats; Rats, Wistar; Sciatic Nerve; Superoxide Dismutase | 2016 |
Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target.
Topics: Amines; Amitriptyline; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; Gait Disorders, Neurologic; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Male; Metacarpus; Mice; Mice, Inbred C57BL; Motor Activity; Oxycodone; Pain; Pain Threshold; Proglumide; Receptor, Cholecystokinin B; Sensory Receptor Cells; Transcriptome; Weight-Bearing | 2016 |
Microwave-assisted on-spot derivatization for gas chromatography-mass spectrometry based determination of polar low molecular weight compounds in dried blood spots.
Topics: 3-Hydroxybutyric Acid; Amines; Butylene Glycols; Calibration; Cyclohexanecarboxylic Acids; Dried Blood Spot Testing; Forensic Toxicology; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Hydroxybutyrates; Microwaves; Molecular Weight; Specimen Handling | 2016 |
Comparative persistence of antiepileptic drugs in patients with epilepsy: A STROBE-compliant retrospective cohort study.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Lamotrigine; Male; Medication Adherence; Middle Aged; Oxcarbazepine; Phenytoin; Proportional Hazards Models; Retrospective Studies; Risk Factors; Taiwan; Topiramate; Triazines; Valproic Acid; Young Adult | 2016 |
Gabapentin, Pregabalin and Vigabatrin Quantification in Human Serum by GC-MS After Hexyl Chloroformate Derivatization.
Topics: Amines; Anticonvulsants; Calibration; Computer-Aided Design; Cyclohexanecarboxylic Acids; Formates; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Pregabalin; Vigabatrin | 2016 |
Palmitoylethanolamide Reverses Paclitaxel-Induced Allodynia in Mice.
Topics: Amides; Amines; Animals; Cyclohexanecarboxylic Acids; Drug Synergism; Ethanolamines; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Mice; Paclitaxel; Palmitic Acids; PPAR alpha | 2016 |
Comparative effects of α2δ-1 ligands in mouse models of colonic hypersensitivity.
Topics: Amines; Animals; Calcium Channels; Cyclohexanecarboxylic Acids; Dextran Sulfate; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Inflammatory Bowel Diseases; Ligands; Male; Mice; Mice, Inbred C57BL; Pregabalin | 2016 |
Small Fiber Neuropathy in Children: Two Case Reports Illustrating the Importance of Recognition.
Topics: Adolescent; Amines; Analgesics; Biopsy; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Erythromelalgia; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Paresthesia; Pruritus; Skin; Small Fiber Neuropathy | 2016 |
Cost of treatment of peripheral neuropathic pain with pregabalin or gabapentin in routine clinical practice: impact of their loss of exclusivity.
Topics: Adult; Aged; Amines; Analgesics; Comoros; Cyclohexanecarboxylic Acids; Electronic Health Records; Female; Gabapentin; gamma-Aminobutyric Acid; Health Expenditures; Health Services; Humans; Male; Middle Aged; Neuralgia; Pregabalin; Primary Health Care; Retrospective Studies; Severity of Illness Index; Socioeconomic Factors; Spain | 2017 |
A rodent model of HIV protease inhibitor indinavir induced peripheral neuropathy.
Topics: Amines; Analgesics; Animals; Calcitonin Gene-Related Peptide; Calcium-Binding Proteins; Cyclohexanecarboxylic Acids; Disease Models, Animal; Exploratory Behavior; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; HIV Infections; HIV Protease Inhibitors; Hyperalgesia; Indinavir; Male; Metacarpus; Microfilament Proteins; Microglia; Neuralgia; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Wistar; Spinal Cord; Statistics, Nonparametric | 2017 |
Dried blood spot analysis of gabapentin as a valid alternative for serum: a bridging study.
Topics: Adolescent; Adult; Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Dried Blood Spot Testing; Drug Monitoring; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Healthy Volunteers; Humans; Middle Aged; Reference Values; Regression Analysis; Reproducibility of Results; Specimen Handling; Tandem Mass Spectrometry; Time Factors; Young Adult | 2017 |
Neuroprotective Effect of Genistein in Peripheral Nerve Injury.
Topics: Amines; Animals; Anti-Inflammatory Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; GAP-43 Protein; Genistein; Interleukin-1beta; Male; Myelin Basic Protein; Nerve Crush; Neuralgia; Neuroprotective Agents; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Recovery of Function; Sciatic Nerve; Sciatic Neuropathy; Treatment Outcome; Tumor Necrosis Factor-alpha | 2017 |
6-Methoxyflavanone attenuates mechanical allodynia and vulvodynia in the streptozotocin-induced diabetic neuropathic pain.
Topics: Amines; Animals; Computer Simulation; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Female; Flavanones; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Models, Molecular; Naloxone; Neuralgia; Nociception; Pentylenetetrazole; Rats, Sprague-Dawley; Receptors, GABA; Streptozocin; Toxicity Tests, Acute; Vulvodynia | 2016 |
[Mirogabalin: The next pregabalin?]
Topics: Amines; Analgesics; Bridged Bicyclo Compounds; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin | 2017 |
Vendor-derived differences in injury-induced pain phenotype and pharmacology of Sprague-Dawley rats: Does it matter?
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Inflammation; Male; Morphine; Neuralgia; Pain Measurement; Phenotype; Rats; Rats, Sprague-Dawley; Species Specificity; Treatment Outcome | 2017 |
Involvement of l-type amino acid transporter 1 in the transport of gabapentin into human placental choriocarcinoma cells.
Topics: Amines; Anticonvulsants; Biological Transport; Blotting, Western; Cell Culture Techniques; Cell Line, Tumor; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Gene Knockdown Techniques; Humans; Large Neutral Amino Acid-Transporter 1; Placenta; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction | 2017 |
Using a graphical risk tool to examine willingness to take migraine prophylactic medications.
Topics: Amines; Analgesics; Antidepressive Agents; Antihypertensive Agents; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Longitudinal Studies; Male; Migraine Disorders; Pain Measurement; Pre-Exposure Prophylaxis; Propranolol; Retrospective Studies; Surveys and Questionnaires; Valproic Acid; Venlafaxine Hydrochloride | 2016 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents; Arthroplasty, Replacement, Shoulder; Bupivacaine; Cyclohexanecarboxylic Acids; Dexamethasone; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Length of Stay; Liposomes; Male; Middle Aged; Narcotics; Nerve Block; Pain Management; Pain Measurement; Pain, Postoperative; Perioperative Care; Retrospective Studies | 2017 |
Topical gabapentin gel alleviates allodynia and hyperalgesia in the chronic sciatic nerve constriction injury neuropathic pain model.
Topics: Administration, Topical; Amines; Analgesics; Animals; Constriction, Pathologic; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Motor Activity; Neuralgia; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy | 2017 |
Psychoactive medications and disengagement from office based opioid treatment (obot) with buprenorphine.
Topics: Adult; Amines; Analgesics, Opioid; Buprenorphine; Clonidine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Opiate Substitution Treatment; Opioid-Related Disorders; Prevalence; Retrospective Studies | 2017 |
A thrombotic storm.
Topics: Aged; Alprazolam; Amines; Amputation, Surgical; Atorvastatin; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Methicillin-Resistant Staphylococcus aureus; Thrombophilia; Ticlopidine; Venous Insufficiency; Venous Thrombosis | 2017 |
An Atypical Withdrawal Syndrome in Neonates Prenatally Exposed to Gabapentin and Opioids.
Topics: Amines; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Infant, Newborn; Methadone; Neonatal Abstinence Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Retrospective Studies | 2017 |
sec-Butylpropylacetamide (SPD), a new amide derivative of valproic acid for the treatment of neuropathic and inflammatory pain.
Topics: Amides; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Inflammation; Male; Mice; Neuralgia; Pain; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Valproic Acid | 2017 |
Paradoxical vestibular syndrome in a dog from western Newfoundland infected with French heartworm
Topics: Amines; Analgesics; Angiostrongylus; Animals; Anthelmintics; Cyclohexanecarboxylic Acids; Dexamethasone; Diphenhydramine; Dog Diseases; Dogs; Gabapentin; gamma-Aminobutyric Acid; Histamine Antagonists; Immunosuppressive Agents; Macrolides; Male; Newfoundland and Labrador; Strongylida Infections; Vestibular Diseases | 2016 |
A codon-optimized Mecp2 transgene corrects breathing deficits and improves survival in a mouse model of Rett syndrome.
Topics: Amines; Animals; Apnea; Codon; Cyclohexanecarboxylic Acids; Dependovirus; Disease Models, Animal; Disease Progression; Gabapentin; gamma-Aminobutyric Acid; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Male; Mesencephalon; Methyl-CpG-Binding Protein 2; Mice, Inbred C57BL; Mice, Knockout; Respiration; Rett Syndrome; Survival Analysis; Tyrosine 3-Monooxygenase; Weight Gain | 2017 |
Multimodal Analgesic Therapy With Gabapentin and Its Association With Postoperative Respiratory Depression.
Topics: Adult; Aged; Amines; Analgesia; Analgesics; Analgesics, Opioid; Combined Modality Therapy; Critical Care; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Pain Management; Pain Measurement; Pain, Postoperative; Postoperative Complications; Postoperative Period; Respiratory Insufficiency; Retrospective Studies | 2017 |
Agomelatine: a new opportunity to reduce neuropathic pain-preclinical evidence.
Topics: Acetamides; Adrenergic alpha-2 Receptor Antagonists; Amines; Animals; Antineoplastic Agents; Constriction, Pathologic; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Disease Models, Animal; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Hypnotics and Sedatives; Idazoxan; Male; Motor Activity; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Pain Measurement; Rats; Rats, Sprague-Dawley; Thiophenes | 2017 |
Antiepileptic drugs: Impacts on human serum paraoxonase-1.
Topics: Amines; Anticonvulsants; Aryldialkylphosphatase; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Kinetics; Levetiracetam; Phenytoin; Piracetam; Primidone; Turkey; Valproic Acid | 2017 |
Pharmacokinetics and Saturable Absorption of Gabapentin in Nursing Home Elderly Patients.
Topics: Aged; Aged, 80 and over; Amines; Analgesics; Anticonvulsants; Biological Availability; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Female; Gabapentin; gamma-Aminobutyric Acid; Glomerular Filtration Rate; Homes for the Aged; Humans; Male; Middle Aged; Models, Biological; Nonlinear Dynamics; Nursing Homes; Prospective Studies; Tissue Distribution | 2017 |
Formalin injection produces long-lasting hypersensitivity with characteristics of neuropathic pain.
Topics: Activating Transcription Factor 3; Amines; Animals; Cyclohexanecarboxylic Acids; Female; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Expression Regulation; Indomethacin; Injections; Ligation; Morphine; Neuralgia; Rats; Time Factors | 2017 |
Protective effects of gabapentin against the seizure susceptibility and comorbid behavioral abnormalities in the early socially isolated mice.
Topics: Aggression; Amines; Animals; Anticonvulsants; Anxiety; Behavior, Animal; Comorbidity; Cyclohexanecarboxylic Acids; Disease Susceptibility; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Housing; Locomotion; Maze Learning; Mice; Seizures; Social Isolation; Stress, Psychological | 2017 |
Antinociceptive interaction of gabapentin with minocycline in murine diabetic neuropathy.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Male; Mice; Minocycline; Pain Measurement | 2017 |
Changing general medical practices in the management of neuropathic pain
Topics: Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Female; Gabapentin; gamma-Aminobutyric Acid; General Practitioners; Humans; Male; Middle Aged; Neuralgia; Pain Management; Practice Patterns, Physicians'; Pregabalin; Surveys and Questionnaires | 2016 |
Gabapentin decreases microglial cells and reverses bilateral hyperalgesia and allodynia in rats with chronic myositis.
Topics: Amines; Animals; Astrocytes; Behavior, Animal; Cell Count; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Microglia; Myalgia; Myositis; Rats; Rats, Wistar; Spinal Cord Dorsal Horn | 2017 |
MechanoAPI-ILs: Pharmaceutical Ionic Liquids Obtained through Mechanochemical Synthesis.
Topics: Amines; Chemistry Techniques, Synthetic; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; Green Chemistry Technology; Ionic Liquids; Mechanical Phenomena | 2017 |
One-Year Swallowing Outcomes in Patients Treated with Prophylactic Gabapentin During Radiation-Based Treatment for Oropharyngeal Cancer.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Deglutition; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Oropharyngeal Neoplasms; Outcome and Process Assessment, Health Care; Pain Management; Prospective Studies | 2017 |
Angiography in Complex Regional Pain Syndrome.
Topics: Amines; Analgesics; Anesthetics, Local; Angiography; Complex Regional Pain Syndromes; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Finger Injuries; Gabapentin; gamma-Aminobutyric Acid; Humans; Lidocaine; Middle Aged | 2017 |
An Improved Rodent Model of Trigeminal Neuropathic Pain by Unilateral Chronic Constriction Injury of Distal Infraorbital Nerve.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Grooming; Hyperalgesia; Male; Neuralgia; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Time Factors; Trigeminal Neuralgia | 2017 |
Gabapentin-Induced Bullous Pemphigoid.
Topics: Aged, 80 and over; Amines; Biopsy, Needle; Cyclohexanecarboxylic Acids; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Immunohistochemistry; Male; Pemphigoid, Bullous; Rare Diseases; Risk Assessment; Seizures; Severity of Illness Index; Withholding Treatment | 2017 |
Donepezil, an Acetylcholinesterase Inhibitor, Can Attenuate Gabapentinoid-Induced Somnolence in Patients with Neuropathic Pain: A Retrospective Chart Review.
Topics: Adult; Aged; Aged, 80 and over; Amines; Cholinesterase Inhibitors; Cyclohexanecarboxylic Acids; Disorders of Excessive Somnolence; Donepezil; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Male; Middle Aged; Neuralgia; Pain Measurement; Piperidines; Pregabalin; Retrospective Studies | 2017 |
Neutrophils Infiltrate the Spinal Cord Parenchyma of Rats with Experimental Diabetic Neuropathy.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Male; Neuralgia; Neutrophil Infiltration; Pain Threshold; Rats; Rats, Sprague-Dawley; Spinal Cord | 2017 |
Gabapentin Inhibits Protein Kinase C Epsilon Translocation in Cultured Sensory Neurons with Additive Effects When Coapplied with Paracetamol (Acetaminophen).
Topics: Acetaminophen; Amines; Analgesics; Animals; Cells, Cultured; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Humans; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells | 2017 |
A case of infant delirium in the neonatal intensive care unit.
Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acids; Delirium; Deprescriptions; Dexmedetomidine; Diazepam; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Methadone; Midazolam; Phenobarbital; Postoperative Complications; Pregnancy; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Risperidone | 2017 |
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Topics: Amines; Animals; Autoradiography; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Functional Laterality; Gabapentin; gamma-Aminobutyric Acid; Haplorhini; Hyperalgesia; Inhibitory Concentration 50; Male; Mice; Mice, Knockout; Naphthyridines; Neuralgia; Protein Binding; Protein Serine-Threonine Kinases; Radioligand Assay; Rats; Spinal Cord Injuries; Tritium | 2017 |
Topical ketamine-amitriptyline-lidocaine for chronic pruritus: A retrospective study assessing efficacy and tolerability.
Topics: Aged; Amines; Amitriptyline; Analgesics; Chronic Disease; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Lidocaine; Male; Mianserin; Mirtazapine; Pain Measurement; Pruritus; Retrospective Studies | 2017 |
Neuropathic pain-induced enhancement of spontaneous and pain-evoked neuronal activity in the periaqueductal gray that is attenuated by gabapentin.
Topics: Action Potentials; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Male; Neuralgia; Neuronal Plasticity; Neurons; Paclitaxel; Periaqueductal Gray; Rats; Rats, Sprague-Dawley | 2017 |
Gabapentin-induced aquagenic wrinkling of the palms.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hand Dermatoses; Humans; Male; Neuralgia; Skin; Water | 2017 |
Levetiracetam synergizes with gabapentin, pregabalin, duloxetine and selected antioxidants in a mouse diabetic painful neuropathy model.
Topics: Amines; Analgesics; Animals; Anticonvulsants; Antioxidants; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Duloxetine Hydrochloride; Gabapentin; gamma-Aminobutyric Acid; Levetiracetam; Male; Mice; Mice, Inbred C57BL; Piracetam; Pregabalin | 2017 |
Restless legs syndrome/Willis-Ekbom disease in type 2 diabetes as the initial manifestation of Parkinson's disease and major cardiovascular disease.
Topics: Aged; Amines; Analgesics; Anticonvulsants; Antihypertensive Agents; Antiparkinson Agents; Aspirin; Biphenyl Compounds; Carotid Stenosis; Clonazepam; Coronary Artery Disease; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypertension; Irbesartan; Male; Parkinson Disease; Quality of Life; Restless Legs Syndrome; Sleep; Tetrazoles; Treatment Outcome | 2017 |
Bilateral Breast Reduction Without Opioid Analgesics: A Comparative Study.
Topics: Adult; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthesia, Local; Anesthetics, Local; Celecoxib; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Mammaplasty; Middle Aged; Nerve Block; Pain Management; Pain Measurement; Pain, Postoperative; Postoperative Complications; Preoperative Care; Prospective Studies; Retrospective Studies; Time Factors; Treatment Outcome; Young Adult | 2017 |
Validated Method for the Screening and Quantification of Baclofen, Gabapentin and Pregabalin in Human Post-Mortem Whole Blood Using Protein Precipitation and Liquid Chromatography-Tandem Mass Spectrometry.
Topics: Amines; Autopsy; Baclofen; Chemical Precipitation; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Reproducibility of Results; Tandem Mass Spectrometry | 2017 |
Urinary Concentrations of Topically Administered Pain Medications.
Topics: Administration, Oral; Administration, Topical; Amines; Amitriptyline; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Drug Monitoring; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Limit of Detection; Skin Absorption; Substance Abuse Detection | 2017 |
Cocrystal solubility product analysis - Dual concentration-pH mass action model not dependent on explicit solubility equations.
Topics: Amines; Carbamazepine; Chemistry, Pharmaceutical; Crystallization; Cyclohexanecarboxylic Acids; Drug Stability; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrogen-Ion Concentration; Indomethacin; Models, Molecular; Molecular Conformation; Nevirapine; Osmolar Concentration; Solubility; Thermodynamics | 2017 |
Stability of gabapentin in extemporaneously compounded oral suspensions.
Topics: Administration, Oral; Amines; Anticonvulsants; Capsules; Chromatography, High Pressure Liquid; Cold Temperature; Cyclohexanecarboxylic Acids; Drug Compounding; Drug Stability; Drug Storage; Gabapentin; gamma-Aminobutyric Acid; Humans; Powders; Suspensions | 2017 |
Spinal Arachnoid Diverticula: Outcome in 96 Medically or Surgically Treated Dogs.
Topics: Amines; Animals; Arachnoid Cysts; Carbazoles; Cyclohexanecarboxylic Acids; Dog Diseases; Dogs; Female; Gabapentin; gamma-Aminobutyric Acid; Male; Prednisone; Retrospective Studies; Surveys and Questionnaires; Treatment Outcome | 2017 |
Characterization of the Effects of L-4-Chlorokynurenine on Nociception in Rodents.
Topics: Amines; Analgesics; Animals; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Kynurenic Acid; Kynurenine; Male; Prodrugs; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2017 |
Opioid free general anesthesia: A paradigm shift?
Topics: Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, General; Bariatric Surgery; Contraindications, Procedure; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hemodynamics; Humans; Hydrocortisone; Hypnosis, Anesthetic; Intraoperative Awareness; Neuromuscular Blockade; Pain, Postoperative; Postoperative Complications; Retrospective Studies | 2017 |
Use of gabapentin in the treatment of chronic pain in an adolescent with sickle cell disease.
Topics: Administration, Oral; Adolescent; Amines; Analgesics; Anemia, Sickle Cell; Chronic Pain; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Patient Admission; Treatment Outcome | 2017 |
Prevalence of Gabapentin Abuse: Comparison with Agents with Known Abuse Potential in a Commercially Insured US Population.
Topics: Adolescent; Adult; Amines; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Prevalence; Substance-Related Disorders; Young Adult | 2017 |
Combination therapy of levetiracetam and gabapentin against nonconvulsive seizures induced by penetrating traumatic brain injury.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Gabapentin; gamma-Aminobutyric Acid; Head Injuries, Penetrating; Levetiracetam; Male; Piracetam; Rats; Rats, Sprague-Dawley; Seizures | 2017 |
Murine model and mechanisms of treatment-induced painful diabetic neuropathy.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Disease Models, Animal; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; GTPase-Activating Proteins; Guanine Nucleotide Exchange Factors; Hyperalgesia; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Conduction; Neuralgia; Pain Threshold; Reaction Time; Receptor, Insulin; Receptors, Leptin | 2017 |
ANTI-NOCICEPTIVE EFFECT OF AGRIMONIA EUPATORIA EXTRACT ON A CISPLATIN-INDUCED NEUROPATHIC MODEL.
Topics: Agrimonia; Amines; Analgesics; Animals; Cisplatin; Cyclohexanecarboxylic Acids; Foot; Gabapentin; gamma-Aminobutyric Acid; Male; Neuralgia; Pain Threshold; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley | 2016 |
Risk to heroin users of polydrug use of pregabalin or gabapentin.
Topics: Adult; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Interactions; Drug Overdose; Drug Users; England; Female; Gabapentin; gamma-Aminobutyric Acid; Heroin Dependence; Humans; Male; Mice; Middle Aged; Pregabalin; Risk; Wales; Young Adult | 2017 |
Law enforcement-derived data on gabapentin diversion and misuse, 2002-2015: diversion rates and qualitative research findings.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Data Collection; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Law Enforcement; Male; Prescription Drug Diversion; Qualitative Research; Substance-Related Disorders; Surveys and Questionnaires | 2017 |
Characteristics, resource utilization and safety profile of patients prescribed with neuropathic pain treatments: a real-world evidence study on general practices in Europe - the role of the lidocaine 5% medicated plaster.
Topics: Aged; Aged, 80 and over; Amines; Anesthetics, Local; Cyclohexanecarboxylic Acids; Duloxetine Hydrochloride; Europe; Female; Gabapentin; gamma-Aminobutyric Acid; General Practice; Humans; Lidocaine; Male; Middle Aged; Neuralgia; Pregabalin; Retrospective Studies; Treatment Outcome | 2017 |
More Treatments on Deck for Alcohol Use Disorder.
Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Amines; Baclofen; Cyclohexanecarboxylic Acids; Cytidine Diphosphate Choline; Disulfiram; Drug Repositioning; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Mifepristone; Naltrexone; National Institute on Alcohol Abuse and Alcoholism (U.S.); Off-Label Use; Patient Acceptance of Health Care; Taurine; Topiramate; United States; Varenicline | 2017 |
Radiologic Findings in Gabapentin-Induced Myositis.
Topics: Adult; Amines; Analgesics; Biomarkers; Computed Tomography Angiography; Contrast Media; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Leg; Magnetic Resonance Imaging; Myositis; Neuralgia; Ultrasonography, Doppler | 2017 |
Remarkable Modulation of Self-Assembly in Short γ-Peptides by Neighboring Ions and Orthogonal H-Bonding.
Topics: Amines; Amino Acid Sequence; Anticonvulsants; Arginine; Binding Sites; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrogen Bonding; Kinetics; Lysine; Protein Conformation; Protein Multimerization; Static Electricity | 2017 |
The Effect of Gabapentin and Tramadol in Cancer Pain Induced by Glioma Cell in Rat Femur.
Topics: Amines; Analgesics; Animals; Bone Neoplasms; Brain Neoplasms; Cancer Pain; Cell Line, Tumor; Cell Survival; Cyclohexanecarboxylic Acids; Femur; Gabapentin; gamma-Aminobutyric Acid; Glioblastoma; Hyperalgesia; Neoplasm Transplantation; Pain Measurement; Rats; Tramadol; Treatment Outcome | 2017 |
Very-Low-Dose Methadone To Treat Refractory Neuropathic Pain in Children with Cancer.
Topics: Amines; Analgesics; Analgesics, Opioid; Cancer Pain; Child; Child, Preschool; Chronic Pain; Cyclohexanecarboxylic Acids; Drug Dosage Calculations; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Methadone; Neuralgia; Treatment Outcome | 2017 |
Dento-corneal aberrant regeneration as evidence of V2 innervation of the inferior human cornea.
Topics: Amines; Brain; Cornea; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Nerve Regeneration; Tooth; Young Adult | 2017 |
Pregabalin and heart failure: A population-based study.
Topics: Aged; Aged, 80 and over; Amines; Anticonvulsants; Calcium Channel Blockers; Cohort Studies; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Heart Failure; Humans; Male; Ontario; Population Surveillance; Pregabalin; Retrospective Studies; Seizures | 2017 |
Effect of Gabapentin/Memantine on the Infantile Nystagmus Syndrome in the Zebrafish Model: Implications for the Therapy of Ocular Motor Diseases.
Topics: Amines; Animals; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Disease Models, Animal; Excitatory Amino Acid Antagonists; Eye Movements; Gabapentin; gamma-Aminobutyric Acid; Memantine; Nystagmus, Congenital; Syndrome; Zebrafish | 2017 |
Consensus statement for non-hormonal-based treatments for menopausal symptoms.
Topics: Amines; Anticonvulsants; Antihypertensive Agents; Behavior Therapy; Breast Neoplasms; Clonidine; Consensus; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Isoflavones; Menopause; Plant Preparations; Selective Serotonin Reuptake Inhibitors; Sweating | 2017 |
Sigma 2 Receptor/Tmem97 Agonists Produce Long Lasting Antineuropathic Pain Effects in Mice.
Topics: Amines; Analgesics, Opioid; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Humans; Hyperalgesia; Male; Membrane Proteins; Mice, Inbred C57BL; Molecular Structure; Motor Activity; Neuralgia; Receptors, sigma; RNA, Messenger; Sigma-1 Receptor; Touch | 2017 |
Persistence with antiepileptic drugs in epilepsy patients treated in neurological practices in Germany.
Topics: Adult; Age Factors; Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Humans; Lamotrigine; Male; Medication Adherence; Middle Aged; Patient Dropouts; Risk Factors; Time Factors; Triazines | 2017 |
Haloperidol Decreases Hyperalgesia and Allodynia Induced by Chronic Constriction Injury.
Topics: Amines; Analgesics; Animals; Antipsychotic Agents; Chronic Disease; Constriction, Pathologic; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Haloperidol; Hyperalgesia; Injections, Spinal; Male; Neuralgia; Pain Measurement; Piperazines; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Sulpiride | 2017 |
Treatment of Gabapentin Toxicity With Peritoneal Dialysis: Assessment of Gabapentin Clearance.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Nephropathies; Diabetic Neuropathies; Female; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Kidney Failure, Chronic; Middle Aged; Myoclonus; Peritoneal Dialysis; Poisoning | 2017 |
AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY POSITION STATEMENT ON MENOPAUSE-2017 UPDATE.
Topics: Administration, Cutaneous; Administration, Oral; Aged; Amines; Breast Neoplasms; Cardiovascular Diseases; Cimicifuga; Cognition; Cyclohexanecarboxylic Acids; Diabetes Mellitus; Endocrinology; Estradiol; Estrogen Replacement Therapy; Estrogens; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Middle Aged; Osteoporosis; Phytoestrogens; Phytotherapy; Progesterone; Progestins; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Societies, Medical; Thrombosis; Vasomotor System | 2017 |
Intervertebral Foramen Injection of Ozone Relieves Mechanical Allodynia and Enhances Analgesic Effect of Gabapentin in Animal Model of Neuropathic Pain.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Injections, Spinal; Male; Neuralgia; Ozone; Rats; Rats, Sprague-Dawley | 2017 |
Burning pain attacks and red skin in a young woman.
Topics: Amines; Aspirin; Cyclohexanecarboxylic Acids; Erythromelalgia; Female; Foot Dermatoses; Gabapentin; gamma-Aminobutyric Acid; Humans; Young Adult | 2017 |
Investigation of spinal nerve ligation-mediated functional activation of the rat brain using manganese-enhanced MRI.
Topics: Amines; Animals; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Gyrus Cinguli; Hyperalgesia; Image Enhancement; Ligation; Limbic System; Magnetic Resonance Imaging; Male; Manganese; Neuralgia; Parietal Lobe; Rats, Sprague-Dawley; Somatosensory Cortex; Spinal Nerves; Superior Colliculi | 2018 |
Gabapentin and Pregabalin for Pain - Is Increased Prescribing a Cause for Concern?
Topics: Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Drug Approval; Drug Utilization; Gabapentin; gamma-Aminobutyric Acid; Humans; Inappropriate Prescribing; Neuralgia; Off-Label Use; Pregabalin; United States; United States Food and Drug Administration | 2017 |
A novel non-opioid protocol for medically supervised opioid withdrawal and transition to antagonist treatment.
Topics: Adult; Amines; Analgesics, Opioid; Buprenorphine; Clonidine; Counseling; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydroxyzine; Male; Naltrexone; Narcotic Antagonists; Opiate Substitution Treatment; Opioid-Related Disorders; Retrospective Studies; Substance Withdrawal Syndrome; Treatment Outcome; Young Adult | 2018 |
Factors in Variability of Serial Gabapentin Concentrations in Elderly Patients with Epilepsy.
Topics: Aged; Amines; Anticonvulsants; Biological Availability; Biological Variation, Individual; Cyclohexanecarboxylic Acids; Drug Monitoring; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Intestinal Absorption; Male; Multivariate Analysis; Prospective Studies | 2017 |
Gabapentin prevents cortical spreading depolarization-induced disinhibition.
Topics: Action Potentials; Amines; Animals; Cortical Spreading Depression; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Long-Term Potentiation; Male; Neocortex; Neurons; Rats, Wistar | 2017 |
You Abused What? Getting High with Unique Medications.
Topics: Amines; Anticonvulsants; Antidiarrheals; Antipsychotic Agents; Antitussive Agents; Cyclohexanecarboxylic Acids; Dextromethorphan; Drug Misuse; Gabapentin; gamma-Aminobutyric Acid; Humans; Loperamide; Pregabalin; Quetiapine Fumarate; Substance Withdrawal Syndrome; Substance-Related Disorders | 2017 |
Multiple sites and actions of gabapentin-induced relief of ongoing experimental neuropathic pain.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Gyrus Cinguli; Male; Neuralgia; Nucleus Accumbens; Pain Threshold; Posterior Horn Cells; Rats, Sprague-Dawley; Spinal Nerves | 2017 |
Anti‑inflammatory actions of gabapentin and pregabalin on the substance P‑induced mitogen‑activated protein kinase activation in U373 MG human glioblastoma astrocytoma cells.
Topics: Amines; Anti-Inflammatory Agents; Astrocytoma; Cell Line, Tumor; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Glioblastoma; Humans; Interleukin-6; Interleukin-8; MAP Kinase Signaling System; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pregabalin; Receptors, Neurokinin-1; Substance P | 2017 |
Quantification of the Pharmacodynamic Interaction of Morphine and Gabapentin Using a Response Surface Approach.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Gabapentin; gamma-Aminobutyric Acid; Morphine; Pain, Postoperative; Rats; Rats, Sprague-Dawley | 2017 |
Comparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Ataxia; Benzodiazepines; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Databases, Factual; Diplopia; Dizziness; Epilepsy, Temporal Lobe; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Humans; Lamotrigine; Lethargy; Male; Middle Aged; Oxcarbazepine; Pregabalin; Retrospective Studies; Sclerosis; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Vertigo; Vigabatrin; Vision Disorders; Young Adult | 2017 |
Gabapentin and its salicylaldehyde derivative alleviate allodynia and hypoalgesia in a cisplatin-induced neuropathic pain model.
Topics: Aldehydes; Amines; Animals; Cisplatin; Cyclohexanecarboxylic Acids; Drug Interactions; Female; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Neuralgia; Nociception; Quality of Life; Rats; Rats, Sprague-Dawley; Rotarod Performance Test | 2017 |
Increase in the circulating endocannabinoid 2-arachidonoylglycerol is associated with gabapentin use in septic ICU patients.
Topics: Aged; Aged, 80 and over; Amines; Analgesics; APACHE; Arachidonic Acids; Critical Care; Critical Illness; Cyclohexanecarboxylic Acids; Endocannabinoids; Female; Gabapentin; gamma-Aminobutyric Acid; Glycerides; Humans; Intensive Care Units; Male; Middle Aged; Sepsis | 2017 |
Effects of S 38093, an antagonist/inverse agonist of histamine H3 receptors, in models of neuropathic pain in rats.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Histamine Antagonists; Hyperalgesia; Male; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Pain Threshold; Pregabalin; Rats; Rats, Sprague-Dawley | 2018 |
Gabapentin regulates expression of FGF2 and FGFR1 in dorsal root ganglia via microRNA-15a in the arthritis rat model.
Topics: Amines; Animals; Arthritis, Experimental; Cyclohexanecarboxylic Acids; Disease Models, Animal; Fibroblast Growth Factor 2; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Gene Expression Regulation; Male; MicroRNAs; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptor, Fibroblast Growth Factor, Type 1; Reference Values; Sensitivity and Specificity; Treatment Outcome | 2017 |
A neuropathic pain syndrome associated with hantavirus infection.
Topics: Adult; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hantavirus Pulmonary Syndrome; Humans; Male; Naproxen; Neuralgia; Orthohantavirus; Peripheral Nervous System; Small Fiber Neuropathy; Syndrome | 2017 |
Unilateral Laryngoscopic Findings Associated With Response to Gabapentin in Patients With Chronic Cough.
Topics: Amines; Calcium Channel Blockers; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Laryngoscopy; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Vocal Cords | 2017 |
International Comparisons of Prevalence, Awareness, and Treatment of Pruritus in People on Hemodialysis.
Topics: Aged; Aged, 80 and over; Amines; Antipruritics; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Health Knowledge, Attitudes, Practice; Histamine Antagonists; Humans; Hyperphosphatemia; Internationality; Male; Middle Aged; Morphinans; Nephrology; Practice Patterns, Physicians'; Prevalence; Pruritus; Renal Dialysis; Risk Factors; Spiro Compounds; Surveys and Questionnaires; Uremia | 2017 |
Is gabapentin effective for women with unexplained chronic pelvic pain?
Topics: Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Pelvic Pain; Randomized Controlled Trials as Topic | 2017 |
UK government to reclassify pregabalin and gabapentin after rise in deaths.
Topics: Adverse Drug Reaction Reporting Systems; Amines; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Databases, Factual; Gabapentin; gamma-Aminobutyric Acid; Humans; Practice Patterns, Physicians'; Pregabalin; State Medicine; United Kingdom | 2017 |
Effectiveness of levodopa treatment for diabetic chorea with reduced striatal accumulation in dopamine transporter SPECT: a case report.
Topics: Aged; Amines; Chorea; Corpus Striatum; Cyclohexanecarboxylic Acids; Diabetes Complications; Dopamine Plasma Membrane Transport Proteins; Drug Therapy, Combination; Dyskinesias; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperglycemic Hyperosmolar Nonketotic Coma; Levodopa; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 2017 |
All-Cause and Drug-Related Medical Events Associated with Overuse of Gabapentin and/or Opioid Medications: A Retrospective Cohort Analysis of a Commercially Insured US Population.
Topics: Adult; Amines; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Utilization; Emergency Service, Hospital; Female; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Male; Middle Aged; Retrospective Studies; United States | 2018 |
The flavonoid 6-methoxyflavone allays cisplatin-induced neuropathic allodynia and hypoalgesia.
Topics: Amines; Analgesics; Animals; Antineoplastic Agents; Behavior, Animal; Cisplatin; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Flavones; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Mice; Mice, Inbred BALB C; Neuralgia; Rats; Rats, Sprague-Dawley | 2017 |
Short hybrid peptides incorporating β- and γ-amino acids as antimicrobial agents.
Topics: A549 Cells; Amines; Amino Acids; Anti-Infective Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; HCT116 Cells; Humans; Lysine; Microbial Sensitivity Tests; Oligopeptides; Protein Stability; Pseudomonas aeruginosa; Staphylococcus aureus; Time Factors | 2017 |
The monoacylglycerol lipase inhibitor KML29 with gabapentin synergistically produces analgesia in mice.
Topics: Amines; Analgesics; Animals; Benzodioxoles; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Enzyme Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Monoacylglycerol Lipases; Neuralgia; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Signal Transduction | 2017 |
Gabapentin, opioids, and the risk of opioid-related death: A population-based nested case-control study.
Topics: Adult; Aged; Amines; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cause of Death; Cyclohexanecarboxylic Acids; Drug Overdose; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Ontario; Pain; Respiratory Insufficiency; Risk | 2017 |
Policies to mitigate nonmedical use of prescription medications: how should emerging evidence of gabapentin misuse be addressed?
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Drug and Narcotic Control; Gabapentin; gamma-Aminobutyric Acid; Health Policy; Humans; Physicians; Practice Patterns, Physicians'; Prescription Drug Misuse; Substance-Related Disorders; United States | 2018 |
Population pharmacokinetics of gabapentin in healthy Korean subjects with influence of genetic polymorphisms of ABCB1.
Topics: Adult; Amines; Analgesics; Asian People; ATP Binding Cassette Transporter, Subfamily B; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pharmacogenomic Variants; Polymorphism, Genetic; Republic of Korea; Young Adult | 2017 |
Practical guidance for using multiple data sources in systematic reviews and meta-analyses (with examples from the MUDS study).
Topics: Amines; Bipolar Disorder; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Data Collection; Gabapentin; gamma-Aminobutyric Acid; Humans; Information Storage and Retrieval; Meta-Analysis as Topic; Neuralgia; Quetiapine Fumarate; Research Report; Review Literature as Topic; Treatment Outcome | 2018 |
Effects of the Antiepileptic Drugs Phenytoin, Gabapentin, and Levetiracetam on Bone Strength, Bone Mass, and Bone Turnover in Rats.
Topics: Administration, Oral; Amines; Animals; Anticonvulsants; Bone Density; Bone Remodeling; Bone Resorption; Cancellous Bone; Cyclohexanecarboxylic Acids; Epilepsy; Femur; Fractures, Bone; Gabapentin; gamma-Aminobutyric Acid; Humans; Levetiracetam; Male; Osteoclasts; Phenytoin; Piracetam; Rats; Rats, Sprague-Dawley; Tibia; Tomography, X-Ray Computed | 2017 |
Development of a high-performance, enterprise-level, multimode LC-MS/MS autosampler for drug discovery.
Topics: Amines; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Drug Discovery; Gabapentin; gamma-Aminobutyric Acid; Humans; Microsomes, Liver; Pharmaceutical Preparations; Tandem Mass Spectrometry | 2017 |
Multiple adverse drug reactions and genetic polymorphism testing: A case report with negative result.
Topics: Amines; Amitriptyline; Analgesics; Cyclohexanecarboxylic Acids; Drug Hypersensitivity; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Myelitis, Transverse; Polymorphism, Genetic; Syndrome; Thoracic Vertebrae; Tramadol | 2017 |
Misuse of gabapentin and pregabalin may be underestimated.
Topics: Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Government; Pregabalin; United Kingdom | 2017 |
Targeting hypersensitive corticostriatal terminals in restless legs syndrome.
Topics: Amines; Animals; Cerebral Cortex; Corpus Striatum; Cyclohexanecarboxylic Acids; Dopamine Agonists; Gabapentin; gamma-Aminobutyric Acid; Male; Microdialysis; Optogenetics; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Restless Legs Syndrome | 2017 |
Call for increased pharmacovigilance of gabapentin.
Topics: Adverse Drug Reaction Reporting Systems; Amines; Cyclohexanecarboxylic Acids; Drug-Related Side Effects and Adverse Reactions; Gabapentin; gamma-Aminobutyric Acid; Humans; Pharmacovigilance | 2017 |
Generalized unprovoked vulvodynia; A retrospective study on the efficacy of treatment with amitriptyline, gabapentin or pregabalin.
Topics: Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pain Measurement; Pregabalin; Retrospective Studies; Treatment Outcome; Vulvodynia | 2018 |
Intentional Drug Overdose Involving Pregabalin and Gabapentin: Findings from the National Self-Harm Registry Ireland, 2007-2015.
Topics: Adult; Alcohol Drinking; Amines; Cyclohexanecarboxylic Acids; Drug Overdose; Emergency Service, Hospital; Female; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Ireland; Male; Middle Aged; Pregabalin; Registries; Young Adult | 2018 |
Vulvodynia and depression - a case study.
Topics: Amines; Analgesics; Cyclohexanecarboxylic Acids; Depression; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pelvic Pain; Vulvodynia | 2017 |
Importance of Regular and Maintenance Therapy Adherence in Neuromyelitis Optica (NMO): Lessons from a Repeating Relapse Case.
Topics: Amines; Analgesics; Autoantibodies; Biomarkers; Chronic Disease; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Glucocorticoids; Humans; Immunologic Factors; Immunosuppressive Agents; Middle Aged; Neuromyelitis Optica; Plasma Exchange; Prognosis; Recurrence; Rituximab; Treatment Adherence and Compliance; Treatment Outcome | 2018 |
Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain.
Topics: Amines; Analgesics; Animals; Antineoplastic Agents; Blood Pressure; Cyclohexanecarboxylic Acids; Disease Models, Animal; Fluorobenzenes; Gabapentin; gamma-Aminobutyric Acid; Heart Rate; Locomotion; Male; Neuralgia; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Peripheral Nervous System; Rats; Rats, Sprague-Dawley | 2018 |
Efficacy and safety of combined low doses of either diclofenac or celecoxib with gabapentin versus their single high dose in treatment of neuropathic pain in rats.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Celecoxib; Cyclohexanecarboxylic Acids; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Male; Neuralgia; Oxidative Stress; Pain Measurement; Pain Threshold; Rats, Wistar; Treatment Outcome | 2018 |
Evaluation of the neonatal streptozotocin model of diabetes in rats: Evidence for a model of neuropathic pain.
Topics: Activating Transcription Factor 3; Amines; Animals; Animals, Newborn; Astrocytes; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Male; Metformin; Microglia; Neuralgia; Neuroglia; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Spinal Cord; Streptozocin | 2018 |
Gabapentin Approvals, Off-Label Use, and Lessons for Postmarketing Evaluation Efforts.
Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Off-Label Use; Product Surveillance, Postmarketing | 2018 |
Gabapentin for Chronic Neuropathic Pain.
Topics: Administration, Oral; Amines; Analgesics; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Humans; Meta-Analysis as Topic; Neuralgia, Postherpetic; Off-Label Use | 2018 |
Efficiencies of Low-Level Laser Therapy (LLLT) and Gabapentin in the Management of Peripheral Neuropathy: Diabetic Neuropathy.
Topics: Amines; Animals; Combined Modality Therapy; Creatinine; Cyclohexanecarboxylic Acids; Cytokines; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dinoprostone; Gabapentin; gamma-Aminobutyric Acid; Low-Level Light Therapy; Male; Maze Learning; Peripheral Nervous System Diseases; Rats; S100 Calcium Binding Protein beta Subunit; Streptozocin; Urea | 2018 |
Letter to Editor "Optimizing the dose of local infiltration analgesia and gabapentin for total knee arthroplasty, a randomized single blind trial in 128 patients".
Topics: Amides; Amines; Analgesia; Anesthetics, Local; Arthroplasty, Replacement, Knee; Cyclohexanecarboxylic Acids; Double-Blind Method; Gabapentin; gamma-Aminobutyric Acid; Humans; Nerve Block; Pain, Postoperative; Single-Blind Method; Treatment Outcome | 2018 |
The role of organic cation transporter 2 inhibitor cimetidine, experimental diabetes mellitus and metformin on gabapentin pharmacokinetics in rats.
Topics: Amines; Animals; Cimetidine; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Gabapentin; gamma-Aminobutyric Acid; Male; Metformin; Organic Cation Transporter 2; Rats; Rats, Wistar | 2018 |
Prevalence of gabapentin in drug overdose postmortem toxicology testing results.
Topics: Adult; Amines; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Overdose; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Prevalence; Sex Characteristics; United States | 2018 |
Comment on: "All-Cause and Drug-Related Medical Events Associated with Overuse of Gabapentin and/or Opioid Medications: A Retrospective Cohort Analysis of a Commercially Insured US Population".
Topics: Amines; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Retrospective Studies | 2018 |
Authors' Reply to: Tomoyuki Kawada's Comment on: "All-Cause and Drug-Related Medical Events Associated with Overuse of Gabapentin and/or Opioid Medications: A Retrospective Cohort Analysis of a Commercially Insured US Population''.
Topics: Amines; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Retrospective Studies | 2018 |
Effectiveness of gabapentin as a postoperative analgesic in children undergoing appendectomy.
Topics: Adolescent; Amines; Analgesics, Non-Narcotic; Appendectomy; Appendicitis; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Pain, Postoperative; Retrospective Studies | 2018 |
Differences in associations of antiepileptic drugs and hospitalization due to hyponatremia: A population-based case-control study.
Topics: Aged; Amines; Anticonvulsants; Carbamazepine; Case-Control Studies; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Hyponatremia; Lamotrigine; Levetiracetam; Logistic Models; Male; Multivariate Analysis; Odds Ratio; Oxcarbazepine; Piracetam; Registries; Retrospective Studies; Time Factors; Triazines | 2018 |
Reverse Iontophoretic Extraction of Gabapentin: A Mechanistic Study.
Topics: Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Monitoring; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Iontophoresis; Skin; Skin Absorption; Swine | 2018 |
Effectiveness of gabapentin pharmacotherapy in chemotherapy-induced peripheral neuropathy.
Topics: Adult; Amines; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Ovarian Neoplasms; Paclitaxel; Peripheral Nervous System Diseases | 2018 |
Gastroretentive raft liquid delivery system as a new approach to release extension for carrier-mediated drug.
Topics: Administration, Oral; Amines; Animals; Biological Availability; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Excipients; Gabapentin; gamma-Aminobutyric Acid; Gastric Mucosa; Gels; Half-Life; Male; Pectins; Polysaccharides, Bacterial; Rats | 2018 |
Peripheral gabapentin regulates mosquito allergy-induced itch in mice.
Topics: Amines; Animals; Antipruritics; Calcium Channels; Culicidae; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hypersensitivity; Male; Mice, Inbred ICR; Neurons; Peripheral Nerves; Pruritus; Receptors, Histamine H1; Saliva; TRPV Cation Channels | 2018 |
The FDA and the Next Wave of Drug Abuse - Proactive Pharmacovigilance.
Topics: Amines; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Drug Utilization; Gabapentin; gamma-Aminobutyric Acid; Humans; Loperamide; Opioid-Related Disorders; Pharmacovigilance; Practice Patterns, Physicians'; Prescription Drugs; Secologanin Tryptamine Alkaloids; Substance-Related Disorders; United States; United States Food and Drug Administration | 2018 |
[Effects of HCN2 in the development of peripheral neuropathic pain in rats].
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Neuralgia; Potassium Channels; Pyrimidines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Nerves | 2017 |
Paroxysmal Sympathetic Hyperactivity after Surgery for Cerebral Hemorrhagic Arteriovenous Malformation: A Case Report.
Topics: Adolescent; Adrenergic beta-Antagonists; Amines; Autonomic Nervous System Diseases; Brain Injuries; Cerebral Angiography; Cerebral Hemorrhage; Computed Tomography Angiography; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Intracranial Arteriovenous Malformations; Male; Neurosurgical Procedures; Propranolol; Sympathetic Nervous System; Treatment Outcome | 2018 |
The Management of Menopausal Symptoms in Women Following Breast Cancer: An Overview.
Topics: Amines; Breast Neoplasms; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Life Style; Menopause; Quality of Life | 2018 |
The Association of Gabapentin Use and Dose With Substance Use Disorders Prior to Inpatient Mental Health Treatment: A Cross-Sectional Study.
Topics: Adult; Amines; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Linear Models; Logistic Models; Male; Multivariate Analysis; Substance-Related Disorders | 2018 |
Athetoid Movements as Initial Manifestation of Primary Sjögren Syndrome.
Topics: Aged; Amines; Anticonvulsants; Athetosis; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydroxychloroquine; Movement Disorders; Muscarinic Agonists; Pilocarpine; Sjogren's Syndrome | 2018 |
Managing chronic pain: are gabapentinoids being misused?
Topics: Amines; Analgesics; Chronic Pain; Cyclohexanecarboxylic Acids; Drug Misuse; GABA Agents; Gabapentin; gamma-Aminobutyric Acid; Humans; Pain Management | 2018 |
Hypothyroidism induced by phenytoin and gabapentin: A Case Report.
Topics: Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypothyroidism; Male; Phenytoin; Thyroxine | 2018 |
Need for international classification of gabapentin as a controlled substance.
Topics: Controlled Substances; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Pregabalin | 2018 |
Using time series analysis approaches for improved prediction of pain outcomes in subgroups of patients with painful diabetic peripheral neuropathy.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Biomarkers; Cluster Analysis; Computer Simulation; Diabetic Neuropathies; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Interrupted Time Series Analysis; Male; Middle Aged; Neuralgia; Pain; Pain Measurement; Predictive Value of Tests; Pregabalin; Treatment Outcome | 2018 |
An enigmatic role of tonic inhibition in gabapentin therapy.
Topics: Anticonvulsants; Gabapentin; gamma-Aminobutyric Acid | 2019 |
A rare case of a gabapentin-induced cardiomyopathy.
Topics: Adult; Cardiomyopathies; Female; Gabapentin; gamma-Aminobutyric Acid; Humans | 2019 |
Commentary on "A Call for Caution in Prescribing Gabapentin to Individuals with Concurrent Polysubstance Abuse: A Case Report".
Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin | 2019 |
Gabapentin: Change is in the Wind.
Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; United Kingdom; United States | 2019 |
Parkinsonism associated with gabapentinoid drugs: A pharmacoepidemiologic study.
Topics: Aged; Bayes Theorem; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Parkinsonian Disorders; Pharmaceutical Preparations; Pregabalin | 2020 |
Drug Repositioning: Antimalarial Activities of GABA Analogs in Mice Infected with
Topics: Animals; Antimalarials; Drug Repositioning; Female; Gabapentin; gamma-Aminobutyric Acid; Malaria; Male; Mice; Plasmodium berghei; Pregabalin | 2020 |
Gabapentin reduced drinking in patients with alcohol use disorder and alcohol withdrawal symptoms.
Topics: Alcohol Drinking; Alcoholism; Gabapentin; gamma-Aminobutyric Acid; Humans; Substance Withdrawal Syndrome | 2020 |
Patient Case Report: Gabapentin-Induced Hypoglycemia.
Topics: Amines; Calcium Channels; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoglycemia; Middle Aged | 2022 |
Comment on "Abuse and Misuse of Pregabalin and Gabapentin: A Systematic Review Update".
Topics: Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin | 2021 |
Rab11-dependent recycling of calcium channels is mediated by auxiliary subunit α
Topics: Animals; Brain; Calcium; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Cell Line; Cell Membrane; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Neurites; Neurons; Presynaptic Terminals; Primary Cell Culture; Protein Transport; rab GTP-Binding Proteins; Rats | 2021 |
Restoring invisible and abandoned trials of gabapentin for neuropathic pain: a clinical and methodological investigation.
Topics: Amines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia | 2021 |
[Hepatotoxicity probably associated with gabapentin].
Topics: Amines; Analgesics; Chemical and Drug Induced Liver Injury; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged | 2021 |
Interindividual Variability in the Bioavailability of Gabapentin Enacarbil Extended Release in Healthy Adults: An Analysis of Data From 6 Phase I Studies.
Topics: Administration, Oral; Adult; Area Under Curve; Biological Availability; Carbamates; Cross-Over Studies; Gabapentin; gamma-Aminobutyric Acid; Humans | 2022 |
Misuse of gabapentinoids (pregabalin and gabapentin) in patients with neuropathic pain related to spinal cord injury.
Topics: Amines; Analgesics; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Pregabalin; Spinal Cord Injuries | 2023 |
Cardiovascular risk of gabapentin and pregabalin in patients with diabetic neuropathy.
Topics: Amines; Analgesics; Cardiovascular Diseases; Cyclohexanecarboxylic Acids; Diabetic Neuropathies; Gabapentin; gamma-Aminobutyric Acid; Heart Disease Risk Factors; Heart Failure; Humans; Myocardial Infarction; Pain; Peripheral Vascular Diseases; Pregabalin; Pulmonary Embolism; Retrospective Studies; Risk Factors; Stroke | 2022 |
A simple and easy non-derivatization gas chromatography-mass spectrometry method for simultaneous quantification of valproic acid, gabapentin, pregabalin, and vigabatrin in human plasma.
Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Pregabalin; Valproic Acid; Vigabatrin | 2023 |
The risk of fragility fractures following initiation of gabapentin and pregabalin-A Danish, nationwide, high-dimensional propensity score-matched cohort study.
Topics: Adult; Amines; Analgesics; Cohort Studies; Cyclohexanecarboxylic Acids; Denmark; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Pregabalin; Propensity Score | 2023 |
Abuse and addiction in gabapentinoid drug users for neuropathic pain.
Topics: Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Drug Users; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pregabalin | 2023 |
Comparative Descriptive Analysis of Physician Versus Patient-Directed Gabapentin Usage In Chronic Pain - A Preliminary Report.
Topics: Amines; Analgesics; Chronic Pain; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Physicians; Pilot Projects | 2023 |